Gene PTPN18
PTPN18
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTPN18.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PTPN18.AA | Family.DSP.PD | 24-280 | 16 | 3.3e-07 | 21.1 | In-house | 77-235 (387) | Show / Hide |
Range on Protein: 24-280
Range on HMM: 77-235/387
Sequence Identity: 16% (29 aa)
AVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYkdvLPYDQTRVILSLLQEEGHSDYINGNfirgvdgslayiatqgplphtlldfwrlvwefg
| | . |. .. . |... | ..... | |.. .. | |.| |... .| .. . ... |.. ...| ..|
akqaelngfidvhtfdldtydhfervengkpseilphly---lgsllaaknlewlkelgvtkivnlt---------------------------------
vkvilmacreiengrkrcerywaqeqeplqtglfcitlikekwlnedimlrT------LkvtfqkeSRSVYQLQYmSWPDRGVPSSPDHmlaMVEEARRL
. .... . .. | . ||| || ||.|.|. . . ...| . . .|..|| .. ...
---------------------------------------------------ddkpqftk-------elgikylri-pidDhnapplenl---fekaidfi
QG---SgPEPLCVHCSAGCGRTGVLCTVDYVRQllltqmipPDFSLFDVVLKMRKQRPAAVQTEEQ
eegnds-kgvVlVHCkaGkgRsgtliiaYlmks--------egltleealdwvrskRpgvitpnqg
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| Phosphatase | PTPN18.AA | Subfamily.N12.PD | 26-292 | 55 | 2.1e-127 | 415.0 | In-house | 2-269 (270) | Show / Hide |
Range on Protein: 26-292 Range on HMM: 2-269/270 Sequence Identity: 55% (148 aa) LAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVK .| ||......|...||. |.|| ||...|||.||||||.||||..||.|| .|| .|||||.|||.||.|.|.|||.|||||.|| ||||..||. |. fakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknve VILMACREIENGRKRCERYWAQE-QEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEP ...|||||.|.|.|.|||||..| .|.|..| |..||..||....|...|||||..|||||.|||..|..|||.|||||....|...|..|.||.| .| ivvmaCrevelgkkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaP LCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMF |.||||||.||||.....||||.|| ...||.....||.||..||||.|.|||.|||...|..||... lvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv |
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| Phosphatase | PTPN18.AA | PTPc | 25-293 | 35 | 2.8e-121 | 410.12 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 25-293 Range on HMM: 1-308/308 Sequence Identity: 35% (113 aa) VLAGEFSDIQACSAAWKA---DGVCSTVAGSRPENV--RKNRYK-DVLPYDQTRVILSLLQEE----GHSDYINGNFIRGVDGSLAYIATQGPLPHTLLD .. ||...|. . |..||. . .|||. .||||| |...||.|||.|. ...| ..||||| |.|.| ... .||.||||||||. | GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED FWRLVWEFGVKVILMACREIEN--------GRKRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQK----------ESRSVYQLQYMSWP ||| ||. ....| | |...|. ||. |..|| .| |.. | ...|...|. ...|. .||..||... |.|.|....|..|| FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP DRGVPSSPDHMLAMVEEARRLQGSGPE-------------------PLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQT |.|||.|||..|..... | | . |. | .|||||||||||..|..|.. |.. . ...|..| .||.||| .||| DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN------VDIFQIVKMMRNQRPGMVQT EEQYRFLYHTVAQMFC ||||.|.|. ... . EEQYIFCYRCILEYIK |
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| Phosphatase | PTPN18.AA | Y_phosphatase | 56-290 | 41 | 6.5e-113 | 386.22 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 56-290 Range on HMM: 1-243/243 Sequence Identity: 41% (104 aa) NVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRG-VDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGR-KR-CERYWAQ--EQE | .||||||...||.|||.|. ......||||| |.|.| . |||.||||.|||. |||| ||. ....| | |...|.|| . |..|| . |.. NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ PLQTGLFCITLIKEKWLNEDIMLRTLKVTFQK----ESRSVYQLQYMSWPDRGVPSS-PDHMLAMVEEARRLQG-SGPE--PLCVHCSAGCGRTGVLCTV |.. | |..|...|.. ..|...||..||. . |.|.|....|..|||.|||.| |..|| .... | |. ... | .|||||||||||..|.. PMTYGDFQVTCVSEEH-CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAI DYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ |.. |.. .. .. ..|..| .||.||| .|||||||.|.|..... DIMCQQMEHEGTV---DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | PTPN18.AA | Subfamily.R_Anemone_2.PD | 50-290 | 41 | 7.4e-73 | 236.5 | In-house | 21-259 (262) | Show / Hide |
Range on Protein: 50-290 Range on HMM: 21-259/262 Sequence Identity: 41% (102 aa) AGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQ . .| | .|||| ..|.||.||| |. |..| ||||| |.| | . ||||||.|||.|. ||||.||| . .||.| .||.|.....||| ... salepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWPskg ePLQTGLFCITLIKEKWLnEDIMLRTLKVTFQ--KESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQ-GSGPEPLCVHCSAGCGRTGVLCTVDYVR . . | ..| .|. | .| .||..||. . .|.| | | .| ||||.|||.|. ..|..| ....| || .|. |||||| ||||| ..|| . . -srsygklvvelkeevel-sdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiavdill QLLLT-QMIppdfSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ . ... .|..| ..|.||.. |||..|| |.|... . erikaealv----dvfqtvkqlreqrnlmvqtkdqyefiydvlle |
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| Phosphatase | PTPN18.AA | Subfamily.N3.PD | 48-291 | 39 | 8.8e-71 | 229.3 | In-house | 18-259 (261) | Show / Hide |
Range on Protein: 48-291 Range on HMM: 18-259/261 Sequence Identity: 39% (98 aa) TVAGSRPENVRKNRYKDVLPYDQTRVILsllqEEGHSDYINGNFIR----GVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCER . | .|||. ||||.|.||||.|||.| .|...|||| |.. . . . ||||||||..| |||..||| ...|.| .|.||..| . isaarkpenlaknryrdilpydatrvkl----kesetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChq YWAQEQEPLQTGLFCITLIKEkWLNEDIMLRTLKVTFQK--ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCT || .... |. | | ... || .. ..|| | .. .. |.|...||||..||| |||......| .||. |.|. . ||. |||||| |||||| . yWPetedelefgefsvrceke-detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlil VDYVRQllLTQMIpPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQM .. . |... .. |.| .|| || . |||..||.|. ... .. letala--lieaa-epvypldivrtmrdqramlvqtvsqykfvCeailka |
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| Phosphatase | PTPN18.AA | Subfamily.RB.PD | 48-292 | 38 | 1e-70 | 229.3 | In-house | 18-260 (261) | Show / Hide |
Range on Protein: 48-292 Range on HMM: 18-260/261 Sequence Identity: 38% (96 aa) TVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQ ..| ....| |||.. .||||..|| |. |..| ..|||| |.| | |||||||||.| ||||.||| ...|.| . .|.|...||.|| . vkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYWPa EQEPLQTGLFCITLIKEKWlNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSG--PEPLCVHCSAGCGRTGVLCTVDYV ..|| . | .||..|| ... ..|..|.. .||.|.| |....|||| |||.... .|..|.. |. . .|. ||||||||||. ..| . deepvlyGdikvtllaeke-ldewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrl RQLLLTqmipPD-FSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMF | . . | .| || ..|..| ||||.|| |......... lqaiee----ndyvdvfgvvaelReeRnllvqtekqyifiheclldll |
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| Phosphatase | PTPN18.AA | Subfamily.N_Choan_1.PD | 47-291 | 37 | 3e-70 | 227.8 | In-house | 17-260 (262) | Show / Hide |
Range on Protein: 47-291 Range on HMM: 17-260/262 Sequence Identity: 37% (92 aa) STVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWA ...| ..||| ||||... ||.||| .. .|. ..|||| ||. |..| .|||||||.|..| .||..||| |..| | ||||.|. .| ||| tataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWP QEQEPLQTGLFCITLIKEKWlNEDIMLRTLKV-TFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGP-EPLCVHCSAGCGRTGVLCTVDY .|.. |. | . .. ..|. .. . |..|. . . |.|.| ||.|..|||.|||... ..| .. ..... ||..||||| ||||. ..| . denselklgdvtvkslseee-kktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyialDr VRQLLLTQMIPpdFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQM . . ... . .. .|| ..||.| ||| ||.|.|..| .. lvkaveekaea--ldvkavvaelrkernlmvqtlvqyefvykavlda |
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| Phosphatase | PTPN18.AA | Subfamily.N6.PD | 42-290 | 38 | 1.1e-68 | 222.9 | In-house | 26-292 (295) | Show / Hide |
Range on Protein: 42-290 Range on HMM: 26-292/295 Sequence Identity: 38% (102 aa) ADGVCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLL-QEEGHSDYINGNFIR--------GVDG-S----LAYIATQGPLPHTLLDFWRLVWEFGVKVI . | |...|| .|||||..||.|.|||||. .. |||||.|.|| | | ||||||.|..|. ||||.||..||.|. seklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqensrvi LMACREIENGRKRCERYWAQEQEPLQTGLFCITLIKEKwLNEDIMLRTLKVT---FQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQG--SGP .|.| |...| ||| .|.. .|| .| |.|| ..| .||...|. ..||.|...|... .||| |||..| ..| ..|. .. | . . |. vmttkevergknkCarYWPdeetkketGvitvtsisEk-stadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeeleka EPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ .||||||.|||| . .| | ... .... | . .. ..|.|| ||||.||.|.|..|.. gpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqf |
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| Phosphatase | PTPN18.AA | Subfamily.N13.PD | 48-290 | 40 | 2.1e-66 | 215.2 | In-house | 18-256 (259) | Show / Hide |
Range on Protein: 48-290 Range on HMM: 18-256/259 Sequence Identity: 40% (101 aa) TVAGSRPENVRKNRYKDVLPYDQTRVILSllqEEGHsdYINGNFIRGV--DGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYW . | . || .||||..|||||.|||.|. .|| ||| ..|. . |||.|||||.| |||..||| ..|| | | |.|..|.||| cevgkkkenkdknryrnvlPydetrvklg---degg--yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchryw AQEQ-EPLQTGL-FCITLIKEKWLnEDIMLRTLKVTF--QKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGsGPEPLCVHCSAGCGRTGVLCT ... ..|. . ..|.| . | .. .|.|.|. .||| | .|....||| |||||..... .| | |.|| |. |||||| ||.||| |. Perknkklkvsnrlevellkvqkl-dgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPivvhcsaGiGrsGvlit VDYVRQLLLTQMippDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ | | .|. . .| . ..| |.|.|| . |||..|| | |... . idvvlglierdk---efdvkeivrklreqrqgvvqtkdqyifvykaile |
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| Phosphatase | PTPN18.AA | Subfamily.N9.PD | 52-289 | 43 | 2.4e-65 | 211.9 | In-house | 22-271 (275) | Show / Hide |
Range on Protein: 52-289
Range on HMM: 22-271/275
Sequence Identity: 43% (101 aa)
SRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQ-E
. |..||||.||| ||.||| |. |.|. .||||| ||. | |.|||||||..| ||||.||| | ||.|. | .|.|| .| .||.|. . .
klranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywpleees
PLQTGLFCITLIKEKwLNEDIMLRTLKVT--FQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSG-------------PEPLCVHCSAGCGR
| . .. .. . .|| . |.|... ..|||.| |..|||| ||||| .| ..|..|. |..|. |||||| |||| ..|.|. . | ..
saefgdlsvsnveve-veedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGr
TGVLCTVDYVRQLLLTQMippDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVA
....| ..|.|| ..||.||| | | .|
tGtfitldiclarleevg---tvdvvetvkllrtqrafsiqtpeqyefcylavl
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| Phosphatase | PTPN18.AA | Subfamily.R_Sponge_2.PD | 47-290 | 37 | 6.1e-65 | 210.5 | In-house | 16-259 (262) | Show / Hide |
Range on Protein: 47-290 Range on HMM: 16-259/262 Sequence Identity: 37% (91 aa) STVAGSRPENVRKNRYKDVLPYDQTRVILSLlQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWA |. .. .||| |||.|..||||..|| |. ... ||||| .|. | |||||||||..|. ||||.|||. |. |.| .|||...|..|| .. slsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWP QE-QEPLQTGLFCITLIKEKWLnEDIMLRTLKVTFQK---ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQ-GSGPEPLCVHCSAGCGRTGVLCT .| . | | .|| .|. | .| ..|.||.. .| ... | | ....||. .||.. .|......| | ||.... |.||.| |||| ...| | ekvdeeveygkfkvtlkeeekl-adyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfia VDYVRQLLLTQmipPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ . | . . .|.|. ..| .|. ||...|| |... ... ldsvlerlkae---eeidvfevlktlrtkriglvqdaaqYvfihdalle |
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| Phosphatase | PTPN18.AA | Subfamily.N_Choan_2.PD | 56-290 | 39 | 9.3e-65 | 209.6 | In-house | 21-263 (266) | Show / Hide |
Range on Protein: 56-290
Range on HMM: 21-263/266
Sequence Identity: 39% (96 aa)
NVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGS-LAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQT
| | |||.|.|| .|||.|. |.|. .. ||| |..||.||. .|||..|||| || .|||..|| |. |.|. |.|||.|||||..|.. .
nkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk
G-LFCITLI-KEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPD------HMLAMVEEARRLQG--SGPEPLCVHCSAGCGRTGVLCTVDY
|. . .. .| .|. |... ..|.|.. .| .|||.|||...| ..|.|... || .. ||| |||||| ||||.| ..|.. .
ladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDi
VRQLLLTQMippDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ
|| ... . .. ..||.|.| ||. |||..||..|..
avrlLeetk---kvdvlaiieelRkdRmalvqhpeqyellykavve
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| Phosphatase | PTPN18.AA | Subfamily.R_Anemone_1.PD | 49-290 | 36 | 4e-64 | 207.9 | In-house | 18-255 (258) | Show / Hide |
Range on Protein: 49-290 Range on HMM: 18-255/258 Sequence Identity: 36% (87 aa) VAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQe .....|| .||||.|....|..||.|. |... .||||| ..|. |.. |.||||.||..|. ||||.||. . || |||. |.|..|| . .. . evarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnliegekkkchqYwPd- qEPLQTGLFCITLIKEKWlNEDIMLRTLKVTF--QKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYV- | . ..| |.. |...|||... ..|.| |.|.....|||.|||. .|..... ... .| .|. |||||| ||||. . .| . .|. -stekygelrvslrkkev-fadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaGvgRtGaflvidaml RQLLLTQMIppdfSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ ... .|..| ..|..|| .|||.||| |....| . eqakkekvv----Difnyvkairedrphmvqtkeqyvfihlavle |
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| Phosphatase | PTPN18.AA | Subfamily.RA.PD | 49-290 | 36 | 1.6e-61 | 199.2 | In-house | 20-263 (266) | Show / Hide |
Range on Protein: 49-290 Range on HMM: 20-263/266 Sequence Identity: 36% (91 aa) VAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQE .....|| .|||. ..|||| .||||| .. | .||||| || | .||.|||. .|. ||||..||. . |.| | ....|.|| .| rtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqywpde qEPLQTGLFCITlIKEKWLNEDIMLRTLKVT------FQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPE-PLCVHCSAGCGRTGVLCT . | .. .|.. . ||. .| . || .|.|| | |. . |||. |||... || .... ..|| . |. |||||| |||| ....| -GlvtyGeirve-vkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtfiv VDYVRQLLLTQMIppdFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ | . . .. . .|..| ..|.||| |||.||| |.|... . ldavlervkaerk---ldvfeavkrlrlqrpqmvqtleqyefiykvlle |
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| Phosphatase | PTPN18.AA | Subfamily.RG.PD | 48-290 | 33 | 6e-61 | 197.4 | In-house | 19-261 (264) | Show / Hide |
Range on Protein: 48-290 Range on HMM: 19-261/264 Sequence Identity: 33% (84 aa) TVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQ . . ...|| .|||. ........|| || | .. .|||| ..|.| | .||.|||||..|. ||||..|| ...| | |.||. ...|| . aesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrdedvyWPk EQEPLQTGLFCITLIKEKWLnEDIMLRTL-----KVTFQKEsRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTV ..|||... . .||.... | .....|.. |. .|| | |.|..| .||| |.|.| .| .|. . . . . |. ||.||| ||.|... . kdeplelealkvtllskekl-skytvrdfvlkntkddkeke-rvvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivvhdsaGvgragtyial DYVRQLLLTQMIppdFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ | . | | .. . ...|. ..|..|| |.|||||.|.|... . dtllqqlekeea---vnvyqvlklirakRpglvtteEqyvfiydalle |
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| Phosphatase | PTPN18.AA | Subfamily.R_Ecdysozoa.PD | 47-290 | 36 | 1.8e-59 | 192.2 | In-house | 18-266 (269) | Show / Hide |
Range on Protein: 47-290 Range on HMM: 18-266/269 Sequence Identity: 36% (93 aa) STVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKrCERYWA ||... . || ||||.|. ..|.|||.|. .. . .||||| .||.| . . .|| |.|. |. ||||...| |..| |. |. || |..||..|. stkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknrk-cakyWp QEQEpLQTGLFCITLIKEKWlNEDIMLRTLKVTFQK-----ESRSVYQLQYMSWP-DRGVPSSPDHMLAMVEEARRLQGSG-----PEPLCVHCSAGCGR | | | ..|..|. .| . |.|.|. .| .|| | | .| .|. | || .. .| ..|..| |. |. |||||| ||.|. iede-vqygdilvklvseek-hsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgr TGVLCTVDYvrqLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ . ..| || . ..|..| |.|.||. || ||| |||. .|. sgifvaldl---llqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad |
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| Phosphatase | PTPN18.AA | Subfamily.RK.PD | 50-288 | 32 | 2.5e-58 | 188.5 | In-house | 23-262 (267) | Show / Hide |
Range on Protein: 50-288 Range on HMM: 23-262/267 Sequence Identity: 32% (79 aa) AGSRPENVRKNRYKDVLPYDQTRVILSLLQEEgHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACRE-IENGRKRCERYWAQE .. ...| .|||..|.|.||...|.| .... .|||||...| . . |.|.|||||..|. ||||||.. . |.| .|.|| .|.|| .. iakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyWPed QEpLQTGLFCITLIKEKwLNEDIMLRTLKVTF----QKESRSVYQLQYMSWPDR-GVPSSPDHMLAMVEEARRLQGS-GPEPLCVHCSAGCGRTGVLCTV | . | . ..|.. . |..|.. |...|. |.| | | |.|...||. .|| | .|... . . | . .. |||.||.||.|. ...| te-vrygdikvelveae-ldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtfiai DYVRQLLLTQMIppdFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTV | ... .. . .| .| ..|.... |.|||||.|.| . divlemieregv---vdvfnavktlrnrkvnmveteeqykfvydvi |
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| Phosphatase | PTPN18.AA | Subfamily.N5_RR.PD | 56-289 | 33 | 4.4e-58 | 187.9 | In-house | 23-261 (265) | Show / Hide |
Range on Protein: 56-289 Range on HMM: 23-261/265 Sequence Identity: 33% (81 aa) NVRKNRYKDVLPYDQTRVILSLLQ-EEGHSDYINGNFIRGVDG-SLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEP-L . .|||||..|| ...||.|. . |. .|.||| |.|.| |. | ||.|||||||.|. ||||.... |.||.| . |. |..|..|. .... . sqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyei QTGLFCITLI-KEKWLNEDIMLRTLKVTFQKE-SRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARR---LQGSGPEPLCVHCSAGCGRTGVLCTVD-YVR . . . .|. ..| .|.| ...... .|||. | .|||. .| .....| .|.| .. . |. |||||| ||||. ... || serygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavr QLLLTQMIppdfSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVA || .... .. .| ..| .| |||.|||........ qlreeivv----dvlkivcnlrldrGGmvqtseqyelihralc |
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| Phosphatase | PTPN18.AA | Subfamily.RN.PD | 41-290 | 37 | 6.5e-56 | 180.6 | In-house | 13-261 (264) | Show / Hide |
Range on Protein: 41-290 Range on HMM: 13-261/264 Sequence Identity: 37% (94 aa) KADGvCSTVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGS-LAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRK .|. ... ......||.|||.|.|||||..|| |. ... .||||| .| | |||||||||..|. |||..||| || ||.. .||.| |.| eaep-stkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvk RCERYWAQEQEPLQtGLFCITLIKEKWLNEDIMLRT--LKVTFQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTG .||| .| . . ... . |. |. .| ..|. || ..|.|.| |. ..|||..|||.|. .| . . |.||||.|.||||| . qckrywpdeGsevy-hiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtG VLCTVDYVRQLLLTQMIppDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ .| | . || . . . . ..| ||| |.|..|..| . .||. vyilidlvlerllkGvk--eidiaatlehlrdqrpglvktkdqfefaltavae |
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| Phosphatase | PTPN18.AA | Subfamily.N14.PD | 41-290 | 36 | 8.4e-56 | 180.3 | In-house | 13-272 (275) | Show / Hide |
Range on Protein: 41-290 Range on HMM: 13-272/275 Sequence Identity: 36% (96 aa) KADGVCSTvaGSRPENVRKNRYKDVLPYDQTRVILSLLQEEgHSDYINGNFIRGVDGS--LAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGR ..|...|| .. |||..|||.||||||...|| || .|. ...||| |. . |. . ||..||||..|. |||..||| ||..|.|.|.|.|... redallst--aklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgk KRCERYWAQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVT----FQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEAR---RLQGSGP-------EP . .|. .... .| | . .|. .. .. | ... || |.|. |||. |||.|||. ....| .|| . || |. ||| eksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPP LCVHCSAGCGRTGVLCTVDYvrqLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ ||| |||||| ..| |. | . . |. ..|||| ||| ||.|.|... . vlvhCsaGvGrtGvlilsdl---liatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlik |
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| Phosphatase | PTPN18.AA | Subfamily.N20.PD | 50-290 | 41 | 2e-52 | 169.5 | In-house | 20-254 (257) | Show / Hide |
Range on Protein: 50-290 Range on HMM: 20-254/257 Sequence Identity: 41% (102 aa) AGSRPENVRKNRYKDVLPYDQTRVILSllqeeGHSDYINGNFIRGVDGS--LAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQ .| .| | ||||.|.|||| ||| | |||| ..|| |. |||||||| |. |||..| | .|| | |||| | .| .|| sgnqpsnreknryrdilpydstrvplg-----kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpi -EQEPLQTGLFCITLIKEKWLNeDIMLRTLKVTFQ--KESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGpePLCVHCSAGCGRTGVLCTVDY ..||. | . | . . |. ...| ..| . |.|| |||. |||.| |.| | .. . ||. . .| |. |||||| |||||. || slkkplelkhfrvflenyqilq-yfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshltg--pmvvhcsagigrtgvflcvdv VRQLLLTQMippDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ | .. . | ..|.| .||.|| |||.|||.| | | . vfcaivknc---sfnimdivaqmreqrsgmvqtkeqyhfcydivle |
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| Phosphatase | PTPN18.AA | Subfamily.N1.PD | 49-288 | 34 | 2.6e-49 | 159.3 | In-house | 21-263 (268) | Show / Hide |
Range on Protein: 49-288
Range on HMM: 21-263/268
Sequence Identity: 34% (84 aa)
VAGSRPENVRKNRYKDVLPYDQTRVILsllqEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQE
. .||| .|||.|| ||| .|..| |... |||| ... || |||||||| ||..||| | ..| . .|... .||| ||.|
reaklpenrglnryrdvspydhsrikl----eradvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqe
QEP----LQTGLFCITLIKEKWLNeDIMLRTLKVT--FQKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGS--GPEPLCVHCSAGCGRTGVLC
|.. . ..||.|. . ..|.|... ..|.| ... .| ||| |||.|| .| .. . |.. |. .||||| ||.| |. ||
eeeaellleetklkvkliseerks-yflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtls
TVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTV
. .. . . .|.|..||.| .|| .| || | .
lvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiai
|
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| Phosphatase | PTPN18.AA | Subfamily.N_Nematode_4.PD | 52-292 | 33 | 5.6e-49 | 158.0 | In-house | 22-263 (264) | Show / Hide |
Range on Protein: 52-292 Range on HMM: 22-263/264 Sequence Identity: 33% (81 aa) SRPENVRKNRYKDVLPYDQTRVILSllQEEGHSDYINGNFIRGVDGSlAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEP .| ||||.|.| |.|||.| . . ||| ...| |.. ||.|||||..|| ||| .|.. ..|..| | ||.| ..|.||.....| . aseknsdknryadilcidetrvvlk--nrdpdndyihaswmrmPdkf-ryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksek -LQTGLFCITLIKEKWL-NEDIMLRTLKVTFQK---ESRS----VYQLQYMSWPDRGVPSSPDHMLAMVEEARRlqGSGPEPLCVHCSAGCGRTGVLCTV | . |||...| |..|..|||| . .. | | .|. |.|. | . .. .. . ..|..|||||| ||| | .|| .. . vvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrtatlvGi DYVRQLLltqMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMF . .. . |.| ..|. | |||.. |. ||. ....| dyatiri---renseievldivrelramrlkavqshlqflfllvvlielf |
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| Phosphatase | PTPN18.AA | Subfamily.N_Nematode_1.PD | 54-290 | 33 | 2.3e-48 | 155.9 | In-house | 24-262 (265) | Show / Hide |
Range on Protein: 54-290 Range on HMM: 24-262/265 Sequence Identity: 33% (83 aa) PENVRKNRYKDVLPYDQTRVILSllQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQ .. ||||||| |..||.|. .| |||| |.. . .| .|.|| .|. ||| .| |. |.| |. ||.|.|.|. |.. .... . aqeadknrykdvgcldknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegekl ---TGLFCITL---IKEKWL--NED-IMLRTLKVTF-QKESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGsgpePLCVHCSAGCGRTGVLCTVD . ||. .. | | .|. | .|.|.. ...|.| ..|.. |||||||. .| ..|..| .| |. |||||| |||| . ...| efkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgskg----PivvhCsaGiGrtGtivaie YVRQLLLTQMIPPDFSlfDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ . . || . .| . ..| |.|.|| ..||. || |... . . yildkllegkqiedme--klvkkireqrnysiqtdaqylfvhrvlln |
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| Phosphatase | PTPN18.AA | Subfamily.RC.PD | 50-291 | 33 | 2.9e-48 | 155.7 | In-house | 20-286 (288) | Show / Hide |
Range on Protein: 50-291 Range on HMM: 20-286/288 Sequence Identity: 33% (89 aa) AGSRPENVRKNRYKDVLPYDQTRVIL-------------------SLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMA . ..|| |||| |||||| || | . . | |.||| || . |||.|||| |. ||||...| ||||.| iarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivml CREIENGRKRCERYWaqeQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQ--KESRSVYQLQYMSWPDRGVPSSPDHMLAM-------VEEARRLQGS- . | |..| .|| .| .. .|.. | .|| |.. . |.|| |.|.|| ||.....| | .| .. . |. .. || telkeGdrekcaeyw---eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafk --GPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQmipPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQM |||..| .|||. .... . . | .. .|.|| |.||.|| |..|||| .||...... nfkstpllvhcrdGsqrtGifiallallesleae---ekvdvfqvvkklrkarplmvsveeqyillydvlvet |
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| Phosphatase | PTPN18.AA | Subfamily.N23.PD | 68-288 | 32 | 1e-46 | 150.8 | In-house | 114-345 (350) | Show / Hide |
Range on Protein: 68-288 Range on HMM: 114-345/350 Sequence Identity: 32% (76 aa) YDQTRVILS-LLQEEGHSDYINGNFIRGV-DGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQE-QEPLQTGLFCITLIKE |..|| | . | . ..|||| ... . .| .||||||.. || ||| .||| ..|| | .| |.....|..|| .. |. . | ...| ... hdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslksl KWLNeDIMLRTLKVTFQ--KESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQ---------GSGPEPLCVHCSAGCGRTGVLCTV-DYVRQLLLTQ . . |.|..... . |.| .|....|.. |||.||...||...|.. | | .|. .||||| ||||..| | .|.| . | rsse-gwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagn MIPpdfSLFDVVLKMRKQRPAAVQTEEQYRFLYHTV . . .|| ..|.|| ||.......||. | gii---niprvvrrlrqqRkymvqkkvilkklyeav |
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| Phosphatase | PTPN18.AA | Subfamily.R_Nematode_2.PD | 57-286 | 33 | 1.4e-45 | 146.8 | In-house | 30-254 (261) | Show / Hide |
Range on Protein: 57-286 Range on HMM: 30-254/261 Sequence Identity: 33% (76 aa) VRKNRYKDVLPYDQTRVILslLQEEGHSDyINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQ-EPLQTG |.||.|| ..|.| .... .. | |.. .||||||| | ||| .| | |.| |. .|. ...||.|.. |. . |. | | kdkhRypdvPCkpetavev--ivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlg LFCITLIK-EKWLNEDIMLRTLKVTFQKE---SRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQgsgpEPLCVHCSAGCGRTGVLCTVDYVRQLLLT |. . || |...|. |||||. .. .|.| .|| .||||||| | ... ..| ... ..|. |||||| |||. . ...|. . ... |. rfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkkse----kPivvhCsaGiGRtmafigteylarevea qmiPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYH .| . . ..|..|. ..|||.|. .| ---dptieltealkelrehRwkgiqtesqlywltl |
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| Phosphatase | PTPN18.AA | PTPc_motif | 186-290 | 39 | 8.9e-41 | 142.7 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 186-290 Range on HMM: 1-92/92 Sequence Identity: 39% (43 aa) SVYQLQYMSWPDR-----GVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQ .|....|..||| |||. |..| .... | |..|||||||||||..|..|.. |. .. |..| .|||||| .|||||| TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ---------VDIFQTVKEMRKQRPGMVQTEEQ YRFLYHTVAQ |.|.|. ... YIFCYRCILE |
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| Phosphatase | PTPN18.AA | Subfamily.R_Nematode_3.PD | 48-291 | 25 | 2.3e-36 | 116.7 | In-house | 15-265 (267) | Show / Hide |
Range on Protein: 48-291 Range on HMM: 15-265/267 Sequence Identity: 25% (65 aa) TVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRgVDGSLAYIATQGPL--------PHTLLDFWRLVWEFGVKVILMACREIE---N ..| | ..| ..|...|. . .|||.| . ..|.|. |.. . ..| | ||.|. |. || .. . .|... | | .| . knatslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedge GRKRCERYWAQEQ-EPLQTGLFCI-TLIKEKWLNEDIMLRTLKVTFQK-ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQgsgpEPLCVHCSAGC . . | .|. ... . |. . . . . ..| |.||. |||.|||.| . | |.| .|.....|.|. .|.... .. . |. ||||.| . eeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfveksk----tpvvVHCsdGi GRTGVLCTVDYVRQLLLTQMIppDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQM |...| .... ||..... ...| ... ..||||. |.|||... |.. .. sRsatlaaielgyqliikskg--kldllslikelrkqRagaiqtelelafvilgilkl |
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| Phosphatase | PTPN18.AA | Subfamily.N_Nematode_6.PD | 54-288 | 29 | 1.4e-35 | 114.2 | In-house | 22-248 (253) | Show / Hide |
Range on Protein: 54-288 Range on HMM: 22-248/253 Sequence Identity: 29% (68 aa) PENVRKNRYKDVLPYDQTRVILSllqeEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQ-EPL .. .|||... .|..|. |. . . || |... . .| ||.|| |. .||... ||. |.| | .|.|.... .| ... . . lkfkdrnrytniqCcdagrlkla----ddedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdar QTGLFCITLIKEKWLNEDIMLRTLKVTFQK--ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQgsgpEPLCVHCSAGCGRTGVLCTVDYVrqllL . .| . .. . |. |.||. .. |. | ... .||| ||| | . | ... .. .|. |||||| |||| | . . | . | kitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdk----kPivvhCsaGvGrtGtlalilii----l TQMIPPDF-SLFDVVLKMRKQRPAAVQTEEQYRFLYHTV || .. |.. |.|..| ||||| || . .. | ealrlpdfqgvkdllvklreerfravqtevqylyalrcv |
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| Phosphatase | PTPN18.AA | Subfamily.N_Nematode_5.PD | 55-290 | 25 | 2.6e-35 | 113.0 | In-house | 24-255 (258) | Show / Hide |
Range on Protein: 55-290 Range on HMM: 24-255/258 Sequence Identity: 25% (61 aa) ENVRKNRYKDVLPYDQTRVilslLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQT .|. |||.||| .|.||| .......||| . |. | . .| || |||.| ||||.| . .. ....... | ..... . .... |.. knlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketavsffpletgdylnl GLFCITLIKEKWLNEDIMLRTLKVTFQKESRSVY--QLQYMSWPDRGVPSSPDHMLA-MVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQLLLT | . |. | . ... |..| .. | || .. |.. ||.. .... ..|. . .. .|..|....|.||.| . ..... . | .. gkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnn QmIPPDfsLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQ . |. . ... |.|.||| ||.. || ..| .|.. g-kepn--ideilkkirsqRpgavesliqyasvyaavld |
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| Phosphatase | PTPN18.AA | Subfamily.N_Fungi_PTP1.PD | 54-147 | 36 | 2.9e-24 | 76.9 | In-house | 43-150 (343) | Show / Hide |
Range on Protein: 54-147 Range on HMM: 43-150/343 Sequence Identity: 36% (39 aa) PENVRKNRYKDVLPYDQTRVILS--LL------QEEGHSDYINGNFIRGV------DGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRK | |||||..|||...||.| | .|||| |... . . |||||.||| |. ||.... . .|||||. ..|..... velfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnle RCERYWAQ |.||| . kcyrYWqe |
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| Phosphatase | PTPN18.AA | Subfamily.N_Nematode_egg.PD | 55-292 | 25 | 6.4e-24 | 75.9 | In-house | 25-256 (257) | Show / Hide |
Range on Protein: 55-292 Range on HMM: 25-256/257 Sequence Identity: 25% (62 aa) ENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENgrKRCERYWAQ-EQEPLQ .. | | | | . .|| | | . |.| |...| .| .| || | ||||.|.. |. |.| |..||| || . |.|.|.| nylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyywpkaeseslv T--GLFCITLIKEKWLNeDIMLRTLKVTFQKESRSVYQLQYMSWpDRGVPSSPDHMLAMVEEARRLQgsgpEPLCVHCSAGCGRTGVLCTVDYVRQLLLT | . |. .| . | ..| |. . |.. . | | | .. .|.| .| |.. |. ....| ... || tvpGslrienlkvdska-dplfrvtklklvGgddeelflehwqg-dvnylsdvysplrvlrklrnls----kpvvvqdilGvskaatlvaieiallsllr QMIPpDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMF | . . | .|..|. .|.. .| |.| |.... Gpit-kslvlravvflrlrrrlsvesvllylfvyrlvlffi |
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| Phosphatase | PTPN18.AA | Subfamily.N_Fungi_PTP1.PD | 183-292 | 28 | 4.1e-19 | 59.9 | In-house | 211-342 (343) | Show / Hide |
Range on Protein: 183-292 Range on HMM: 211-342/343 Sequence Identity: 28% (37 aa) ESRSVYQLQYMSWPDRGVPSSPDHMLAMVE----------EARRLQGSGPEPLCVHCSAGCGRTGVLCTVDYVRQ-LLLTQMIPPDFS-----------L | |||||. |.| .. | .| ..| |. . .|. ||||||.||||.|.|.|.. . .. ..... .. epyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDli FDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMF .|...|||| ||. .|. |.|... .| siivnelrkqrismvqnldqfifiYeallfyf |
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| Phosphatase | PTPN18.AA | Subfamily.N_Nematode_eak.PD | 47-207 | 22 | 8.4e-15 | 46.0 | In-house | 17-176 (281) | Show / Hide |
Range on Protein: 47-207 Range on HMM: 17-176/281 Sequence Identity: 22% (36 aa) STVAGSRPENVRKNRYKDVLPYDQTRVILSLLQEEgHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWA | ..| |.|..|| ...|.|. | |. | . . ||| . . || | . . . ||..| | |.. ..|.. .. ..|. sirvtarleavnrnrvvkivpqdrylvrltssqln-rdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfp QEQEPLQTGLFCITLiKEK-WLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPSSPDHM .. | |. | . .. || .. . | |... |. |. .. | . .| | . dktevlkyGildver-keyavkrniletrllilrkGnethrvlhykvfGwtettlpkyedfl |
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| Phosphatase | PTPN18.AA | Subfamily.PTPDC1.PD | 192-285 | 28 | 5.4e-10 | 30.3 | In-house | 139-221 (229) | Show / Hide |
Range on Protein: 192-285 Range on HMM: 139-221/229 Sequence Identity: 28% (26 aa) YMSWPDRGVPSsPDHMLAMVEEARRLQGSGpePLCVHCSAGCGRTGVLCTVdyvrQLLLTQMIPPDfslfDVVLKMRKQRPAAVQTEEQYRFLY ....| ||.| ...| .| . | . ||| || |||||| . |. .. . .. . . ..|..|| ..|| ||... nfglkDygvas-leriLdivkvvdfaleeg--kiavHCHAGlGRtGvliac----ylvyakrltae----eaiklvrskrpksiqtreqvelve |
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| Phosphatase | PTPN18.AA | Subfamily.DSP23.PD | 190-284 | 27 | 8.3e-09 | 26.8 | In-house | 36-120 (128) | Show / Hide |
Range on Protein: 190-284 Range on HMM: 36-120/128 Sequence Identity: 27% (26 aa) LQYMSWPDRGVPSSPD--HMLAMVEEARRLQgsgpEPLCVHCSAGCGRTGVLCTVDYVRQllltQmippDFSLFDVVLKMRKQRPAAVQTEEQYRFL |. .. || |. ... .|||| . . |.. ||| |.|||| | . .|.. . ... | . .||.|. ...||| . . lrridipdfcPPaleqvarlvriveeaekke----eavgvhcalGlGrtGtllacylvke----e----glaaddaiaevrkrrkGsietveqekav |
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| Phosphatase | PTPN18.AA | Subfamily.N_Nematode_eak.PD | 227-289 | 25 | 1.9e-06 | 18.5 | In-house | 216-277 (281) | Show / Hide |
Range on Protein: 227-289 Range on HMM: 216-277/281 Sequence Identity: 25% (16 aa) VHCSAGCGRTGVLCTVDYVRQLLlTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVA . .. | |.||. .| . .|. . . .|. |..||....| .| .. |. |.|. | iqsarGsaraGvfvvidllirli-dnkkknlysvedlilkvkskrihsvlvalqhsfiyeivl |
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