Gene PTPN13
PTPN13
Species: Human
Alias: PTPN13, PNP1, PTP1E, PTP-BL, DKFZp686J1497, FAP-1, PTPLE, PTP-BAS, PTPL1
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTPN13.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kind | PTPN13.AA | KIND | 3-190 | 29 | 8.3e-89 | 302.26 | SMART | 1-242 (242) | Show / Hide |
Range on Protein: 3-190
Range on HMM: 1-242/242
Sequence Identity: 29% (71 aa)
VSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP-SGSVSFTDENIS-----NQDLRAFTAPEVLQNQSLTSLSDV
|||||.||.||.||.||..|||..|...||.| .|.....||.........|.|.|.. .|||.|...... ..|.|.|..||..|.||.|..||.
VSLAEILECRGQPLNEEQAWAVCHQCCRSLRECPRQAHTCDPDYFHRVCCCWDLHLWREDGSVCFQPPEQHTPKEQRPDDRMFVPPEWDQCQSQTDHSDS
-------------------------------EKIHIYSLGMTLYWGADYEVPQSQPIKLGDHLNSILLGMCEDVIYARVSVRTVLDAC------------
||.|||.|||.|||..||.||..|...|..||......||.|....|.........|
SSGDSSVINRAFDNSNHHHHHQHHHPPLVVSEKAHIYCLGMVLYWALDYHVPEHQECQLSQHLEQLIDRMCNDDHHDRCCDEHIEEYCEDWEDEDTEEER
----SAHIRNSNC-APSFSYVKHLVKLVLGNLSGTDQLSCNS
|.|.....| ||......|.............. ....
YQVRSHHHSMRMCRAPHLLQRWHDQNHYQAVCRAMFCETWEM
|
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| FERM | PTPN13.AA | B41 | 568-781 | 27 | 6.1e-65 | 222.98 | SMART | 1-232 (232) | Show / Hide |
Range on Protein: 568-781
Range on HMM: 1-232/232
Sequence Identity: 27% (67 aa)
EDNRRKVNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGL--VEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVN------FTLFFR
|.... ...|. ||...| .|...|..|.|. |.|. .||..|.|. ..|. | . .|. .|. |. .||.||
SPKPRFCRVYFMDGTTLEFEVDSSTTGQDLCDHVCRHCGISPREHWYFGLWYEDPHED--------------RHWLDHWKTIMKQDVKWHKSEPWTLHFR
IKFFMDD----VSLIQHTLTCH-QYYLQLRKDILEERMHCD-DETSLLLASLALQAEYGDYQPE--------VHGVSYFRMEHYLPARVMEKLDLS----
.||. .| ....|.. |.. ..|||.|.|||..| .| .|..|.||.|..|.|||||.|| | . |.. ...|| .... .. |
VKFYPPDWHGFPNQLQEDPTRYNYFYLQCRHDILQGRHPCPHEEECLQLAALQVQIEYGDYDPEETNNKKMTKHVQKYKSYKRFLPKQWIDSIKQSFMHY
-----YIKEELPKLHNTYVGASEKETELEFLKVCQRLT-EYGVHFH
.... . ..|. ..| .. | .|..|..|||.. .|||...
QMHHKEWRKRIMEWHKNHCGMTPEEAKLKYLQICQRWPPMYGVEHF
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| FERM | PTPN13.AA | FERM_M | 666-781 | 25 | 5.4e-44 | 152.11 | Pfam | 1-171 (171) | Show / Hide |
Range on Protein: 666-781
Range on HMM: 1-171/171
Sequence Identity: 25% (43 aa)
DVSL-IQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYG-DYQ-PEVHGVSY-FRME-------------------HYLP-----------
|.. ||. |.||.|||.. ||||.| |..|. |.||....|.|.| ||. |. | ..| .. . .|.|
DPNRDIQDEVTRHQFYLQAKWDILEGRYPCSEEEALMLAAYQCQIEFGSDYNPPQKHKSDYMEKEWWEQQEGMEVWLRCDNEQQERYWPAHCRLASKGRT
--------------------ARVMEKLDLSYIKEELPKLHNTYVGA-SEKETELEFLKVCQRLTEYGVHFH
....|........... .| . | |..| .|.....|||. .|||||.
MADSSYSEVSIRINPHCYVSPWYCKKMKQKQWEQRILEQHKNHRGMCSPEEAMLQYIQICQRWPMYGVHFF
|
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| FERM_C | PTPN13.AA | FERM_C | 787-876 | 30 | 5.4e-33 | 119.3 | Pfam | 1-99 (99) | Show / Hide |
Range on Protein: 787-876 Range on HMM: 1-99/99 Sequence Identity: 30% (30 aa) KKSQTG-ILLGVCSKGVLVFEVHNGVRTL--VLRFPWRETKKISFSKKKITLQN-------TSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQS .|..| ..||||.||..|..| .. . . . .|||.|..||||..||.... ......|.|...|...| ||...|. .|.| ...| ... DKKGTDTWWLGVCAKGINVYQV-QDNNKITPMNTFPWPEIRKISFKRKKFFIKLRDDPDEGEKYEHTHTFYMPNYRACKYLWKCCVEHHQFFRLRRPPDT |
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| FERM | PTPN13.AA | FERM_N | 576-664 | 36 | 2.1e-32 | 118.75 | Pfam | 1-93 (93) | Show / Hide |
Range on Protein: 576-664 Range on HMM: 1-93/93 Sequence Identity: 36% (35 aa) IMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALAT----LKD--NEY-FFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRIKFFM ..||... ||.||| ||.....||.|. |....|.. | |.. |. |.. ...||| |..|....|||. |..|.. ..|||||.||.. VHLLDDTQLECTCDKKTTGQELFDQVCQHLNIRECWYFGLQFCKQNDKKEGNQHMHWLDPDKKICKQMKDGWKH---KIKKKCPPCTLFFRVKFYP |
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| PDZ | PTPN13.AA | PDZ | 1093-1176 | 35 | 9.2e-22 | 77.13 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 1093-1176 Range on HMM: 1-86/86 Sequence Identity: 35% (31 aa) LVNLKKD-AKYGLGFQIIGGEKMGRLDLGIFISSVAPG-GPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPE-DVTLVIS .| |.|. ||||.| ||.. .. | ||.||.| || |.|. .| ...||..||.| .......| |......... |.|.| QVTLEKQDKRGGLGFSIKGGNDQRH-DQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PDZ | PTPN13.AA | PDZ | 1102-1179 | 38 | 8.3e-25 | 89.65 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1102-1179 Range on HMM: 1-80/80 Sequence Identity: 38% (34 aa) YGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDG-----CLKPGDRLISVNS-VSLEGVSHHAAIEILQNAPE-----DVTLVISQPK ||||.| | ||||||| |||||. .| .|.||||...|| ...|...| |...|..... |||.. |. GGLGFSIVG---------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | PTPN13.AA | PDZ | 1368-1455 | 33 | 4.2e-22 | 78.3 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 1368-1455 Range on HMM: 1-86/86 Sequence Identity: 33% (31 aa) EVELAK--NDNSLGISVTVLFDKGGVNTSVRHGGIYVKAVIPQ-GAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQ-VVHLLLE .| | | ..||.|. . |... |||.. |.| |||| .||||.||.....||..... || .||. ...... .|||... QVTLEKQDKRGGLGFSIKGGNDQRH------DQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PDZ | PTPN13.AA | PDZ | 1376-1458 | 30 | 8.1e-23 | 83.04 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1376-1458 Range on HMM: 1-80/80 Sequence Identity: 30% (29 aa) NSLGISVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGR-----IHKGDRVLAVNG-VSLEGATHKQAVETLRNTGQ-----VVHLLLEKGQ ..||.|.. ||... |.| |.|| .|| ...|||.|.||| ...|..|| |||. |...|. .|.|..... GGLGFSIVG--------------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | PTPN13.AA | PDZ | 1506-1591 | 27 | 2.7e-11 | 41.23 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 1506-1591 Range on HMM: 1-86/86 Sequence Identity: 27% (25 aa) EVKLFK--NSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGK-IDVGDVILKVNGASLKGLSQQEVISALRGTAP-EVFLLLC .|.|.| .||||| ..... . . . .... || .||| |. | .||.|...|| .. .... ... |..|. || |.. QVTLEKQDKRGGLGFSIKGGNDQRH----DQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PDZ | PTPN13.AA | PDZ | 1793-1871 | 33 | 3.4e-22 | 78.61 | Pfam | 1-86 (86) | Show / Hide |
Range on Protein: 1793-1871 Range on HMM: 1-86/86 Sequence Identity: 33% (29 aa) LITLIKS-EKGSLGFTVTKGNQRI---GCYVHDVIQD--PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASK-TVRLVIG ..|| |. . |.|||.. || |.|. .|... .|. .||...||..|..|..|..|||| .|| ... ... .|.|.| QVTLEKQDKRGGLGFSIKGGNDQRHDQGIYISEVMPGSGAAERGGRIHEGDQIISINGQDIRNMTHDRAVQAIKGSKGGEVHLTIQ |
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| PDZ | PTPN13.AA | PDZ | 1514-1594 | 23 | 3.3e-17 | 64.42 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1514-1594 Range on HMM: 1-80/80 Sequence Identity: 23% (22 aa) SGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGK-----IDVGDVILKVNG-ASLKGLSQQEVISALRGTAP-----EVFLLLCRPP ||||| . . .....|| ||. .|. . .||.||.||| ........... .|... . .| |...||. GGLGFSIVG------------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | PTPN13.AA | PDZ | 1802-1874 | 32 | 1e-22 | 82.69 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1802-1874 Range on HMM: 1-80/80 Sequence Identity: 32% (28 aa) GSLGFTVTKGNQRIGCYVHDVIQD-PAKSDGR-----LKPGDRLIKVND-TDVTNMTHTDAVNLLRAASK-----TVRLVIGRVL |.|||... |... .|. . || .|| |.||||...||. ..|.|||| .||..|..... .|.|.. | GGLGFSIVG-----GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| PDZ | PTPN13.AA | PDZ | 1896-1971 | 25 | 2.1e-13 | 51.75 | SMART | 1-80 (80) | Show / Hide |
Range on Protein: 1896-1971 Range on HMM: 1-80/80 Sequence Identity: 25% (22 aa) EELGFSLCGGHDSLYQVVYISDINPRSVAAIEGN-----LQLLDVIHYVNG-VSTQGMTLEEVNRALDMSLP-----SLVLKATRND . ||||. | ..||.. | ..|. |. |. |.| ||| .....|| |.. ..| . . ...|. |.. GGLGFSIVG-------GIFISSVVPGGPAEKAGRNTRGHLRPGDRILEVNGQQPVENMTHEQAVDMLKQCGGGGIGDKVTLTVQRPG |
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| Phosphatase | PTPN13.AA | PTPc | 2217-2474 | 32 | 1.7e-116 | 394.24 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 2217-2474 Range on HMM: 1-308/308 Sequence Identity: 32% (104 aa) IPSKELENLQELKPLD---------QCLIGQTKENR--RKNRYK-NILPYDATRVPLGDE---------GGYINASFIKIPVGKEEFVYIACQGPLPTTV ..| |.||...| | .| ... .||| .||||| .|..|| ||| | .. ..||||..|... .... ||..||||| |. GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPLPHTI GDFWQMIWEQKSTVIAMMTQEVEG--------EKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLK-GFVVRAMTLEDIQT--------REVRHISHLNF |||.|.|.||...|.|.....|. ..||..|||. .|. .... ... .... ....| ..... .. |.| . |... EDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE----PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHY TAWPDHDTPSQPDDLLTFISYMRHIHR---------------------SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQ |.||||..|. ||..| || ..|| .. .|||. |||||.||.||...||... .| . .|| ..|. || ||.|||| TNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQ TEDQYIFCYQVILYVLT ||.||||||..||... TEEQYIFCYRCILEYIK |
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| Phosphatase | PTPN13.AA | Subfamily.N13.PD | 2218-2474 | 59 | 6.1e-138 | 449.7 | In-house | 2-259 (259) | Show / Hide |
Range on Protein: 2218-2474 Range on HMM: 2-259/259 Sequence Identity: 59% (153 aa) PSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEV |..|...|.||||||.| .|..|||..||||.|.||||.|||.|||||||||||.||.|||..|..|||||||||.|| |||||.||||..||||.|.|. PaeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdeggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlek EGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR-SGPIITHCSAG |..|.||.||||.. .|...|||||...|...|.|.||||||....|....|.|...||||..||||..||....|..|....|.... .|||..||||| ekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqtdagPivvhcsaG IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLT |||||.||.||||||||..| .||....||..| ||.|.|||.|||||.|..||.||. iGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk |
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| Phosphatase | PTPN13.AA | Y_phosphatase | 2242-2471 | 38 | 6.8e-109 | 372.86 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 2242-2471 Range on HMM: 1-243/243 Sequence Identity: 38% (95 aa) NRRKNRYKNILPYDATRVPLG-----DEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEK-IK-CQRYWPN-ILG |..|||||.|..|| ||| |. . . ||||..|.. ...... ||..|||.| |..|||.|.|.||.|.|.|.....|... .| |..|||. | NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG-PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEG KTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQT--REVRHISHLNFTAWPDHDTPSQ-PDDLLTFISYMRHIHR---SG--PIITHCSAGIGRSGTLIC . . ... .|.........|| ..... .. .|.| . |. .|.||||..|. |...| || ..|. .. .| ||. |||||.||.||... QPMTYG-DFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCA IDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILY ||... .. .. ..|| ..|..|| ||.||||||.|||||||.||. IDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | PTPN13.AA | Subfamily.N20.PD | 2236-2473 | 48 | 6.7e-79 | 256.3 | In-house | 20-256 (257) | Show / Hide |
Range on Protein: 2236-2473 Range on HMM: 20-256/257 Sequence Identity: 48% (116 aa) IGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKT |. || ||||..|||||.|||||| |||||.|.| ||..||| |||| .|. |||||. |..| ||||.|.|.|| ||| .||| | | sgnqpsnreknryrdilpydstrvplgkskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkkp tMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ . ...|. | | |. |..| . . . | . . .|.|| |||| ||. | .. .| | |. | .||.. ||||||||.| ..|.|||. | .. -lelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshltgpmvvhcsagigrtgvflcvdvvfcaivk DLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL |.| |.| || || |||||..|| |||...| || ncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl |
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| Phosphatase | PTPN13.AA | Subfamily.N3.PD | 2225-2471 | 41 | 3.5e-76 | 247.1 | In-house | 9-258 (261) | Show / Hide |
Range on Protein: 2225-2471 Range on HMM: 9-258/261 Sequence Identity: 41% (103 aa) LQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEG-GYINASFIKIPVGKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEK | || . . . || ||||..||||||||| | .. ||||..... . ...| |||.||||..|. |||||.||||||.| |.|. || . lyrkkpglaisaarkpenlaknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGr IKCQRYWPNILGKTTMVsnRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH--RSGPIITHCSAGIGR .|| .|||. .... .... . . .. | .|.| ..|.| .|.| |.| .| ..|||||. |....|.|.|.. .|..... |.. ||||||||.| vkChqyWPetedelefg--efsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigr SGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILY || ... | || . .. . |.|| || || .|||..|| | . || tGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailk |
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| Phosphatase | PTPN13.AA | Subfamily.RB.PD | 2220-2473 | 38 | 2.3e-74 | 241.3 | In-house | 4-260 (261) | Show / Hide |
Range on Protein: 2220-2473 Range on HMM: 4-260/261 Sequence Identity: 38% (100 aa) KELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPL-----GDEGGYINASFIKIPVGKEEfvYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT .|.|.|.... ... ....|| |||..||||||..|| | .. ||||..|. . | |||.|||||.|| |||.|.||.||..| |.| eeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspre--yiatqGPlpetvddfWrmvwekkssiivmlt QEVEGEKIKCQRYWPNilGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDiqTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRS----GPII | ||. |.||..|||. ..... ... |. ..|. .|.| ...| .| |.. ...||.||||..|.... || |..|. ... .||. | qlvEkgkekceeYWPa--deepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPiv THCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL ||||.||.|| | .| .| |... |. .| .| .| .||||.|||| ....| .| vHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldll |
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| Phosphatase | PTPN13.AA | Subfamily.N12.PD | 2236-2471 | 40 | 3.1e-72 | 234.1 | In-house | 26-267 (270) | Show / Hide |
Range on Protein: 2236-2471 Range on HMM: 26-267/270 Sequence Identity: 40% (99 aa) IGQTKENRRKNRYKNILPYDATRVPLG-----DEGGYINASFIKIPVGKEEfvYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPN |...||..|||||.||||| .|| | .. .||||.||| . || | |||.|||||.|. |||.||||.. ... |. .||| .|.||.||||. agekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkle--yiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpe ILGKtTMVSNRLRLALVRMQQLK-GFVVRAMTLEDIqtREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR--SGPIITHCSAGIGRSGTLICID .. .. ......| . .... .|..|....| .| |.. ...||||||..||....|| .|. .|.... . |.. |||||.|| ||.| || egee-elefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaid VVLGLISQDLD---FDISDLVRCMRLQRHGMVQTEDQYIFCYQVILY | |. .. .|. ||| .| ||. .|||..|| . |. .. yvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae |
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| Phosphatase | PTPN13.AA | Subfamily.R_Anemone_2.PD | 2238-2471 | 39 | 1.2e-69 | 226.0 | In-house | 23-259 (262) | Show / Hide |
Range on Protein: 2238-2471 Range on HMM: 23-259/262 Sequence Identity: 39% (94 aa) QTKENRRKNRYKNILPYDATRVPLGDE-----GGYINASFIKIPvgKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNil ... |..|||| |||.|| ||| | . ||||..| ... |||.|.||| |. |||.|.|||.|.|| |.|||.| |.|..||||. lepvnkaknryanilaydktrvklqmlegeegsdyinanyidGy--rrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWPs-- gKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH---RSGPIITHCSAGIGRSGTLICIDVV | .. ..|. | .|. .|.| .... .. |.|.. ..|.|||...|... .|| ....... |||. |||||.|| |. | .|..| -kgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiavdil LGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILY | .. |. . |. .| || ||||.|||.|.|.|.| lerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlle |
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| Phosphatase | PTPN13.AA | Subfamily.R_Sponge_2.PD | 2233-2471 | 34 | 1.8e-69 | 225.4 | In-house | 16-259 (262) | Show / Hide |
Range on Protein: 2233-2471 Range on HMM: 16-259/262 Sequence Identity: 34% (85 aa) QCLIGQTKENRRKNRYKNILPYDATRVPLGD----EGGYINASFIKipVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW .. |...||| |||.|.||||| .|| | .. ||||||. . |.. ||| ||||..||.||| |.||.|.. | |.|. .| .| ||..|| slsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvd--gykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYW PNILGKTTMVSNRlRLALVRMQQLKGFVVRAMTLEDIQTREVRH-ISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR---SGPIITHCSAGIGRSGTLI |. ...... . . .|. ..|. ...| ..| . ...| .. ... .|.|||.|..|.. ||.|. ... .. ...|. .||.|.||.|| |. Pekvdeeveygkf-kvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfi CIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILY .|.|| . .. . |. .... .| .| |.||...|| |.....| aldsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalle |
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| Phosphatase | PTPN13.AA | Subfamily.N6.PD | 2221-2471 | 40 | 1.9e-69 | 225.4 | In-house | 17-292 (295) | Show / Hide |
Range on Protein: 2221-2471
Range on HMM: 17-292/295
Sequence Identity: 40% (112 aa)
ELENLQ--ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDE-----G-GYINASFIKIPV---------GKE--EFVYIACQGPLPTTVGDFWQM
| |.|| | . | .. |. ||..|||||||||.| ||| | | | ||||..|..| . | ||| ||.|..|| |||.|
efeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrm
IWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTmvSNRLRLALVRMQQLKGFVVRAMTLEDI-QTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM
.|...|.|| |.|.||| | || ||||. |.. .... .. .. . ...| .... . .| |.| ...|.|||||..|..| .|.|.. .
vwqensrvivmttkevergknkCarYWPdeetkke--tGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledv
----RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILY
......|||. |||||||| ||.| ||.|| .|.| |.| ||| .. .| || |.||||.||.| |....
nkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqf
|
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| Phosphatase | PTPN13.AA | Subfamily.N_Choan_1.PD | 2234-2473 | 36 | 6.6e-68 | 220.2 | In-house | 18-261 (262) | Show / Hide |
Range on Protein: 2234-2473 Range on HMM: 18-261/262 Sequence Identity: 36% (90 aa) CLIGQTKENRRKNRYKNILPYDATRVPL-----GDEGGYINASFIKIPVGKEEfvYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW . ...||. ||||.|| |||||| . . ||||.|.. |..| |||.|||.|... .||||.|||| ..|.|.|.|.|..|.|| ||| ataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgeke--yiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryW PNILGktTMVSNRLRLALVRMQQLKGFVVRAMTLeDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRS---GPIITHCSAGIGRSGTLIC |. .. ... .. .. | .. | ..| . .. | |....|..|||||| |... .|| | ........ |.. |||||.||.|| | . Pdens--elklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyia IDVVLGLISQDLDF-DISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL | .. ...... |....|. .| .| |||| || | |...| .| lDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal |
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| Phosphatase | PTPN13.AA | Subfamily.R_Anemone_1.PD | 2232-2473 | 33 | 1.8e-64 | 209.1 | In-house | 15-257 (258) | Show / Hide |
Range on Protein: 2232-2473 Range on HMM: 15-257/258 Sequence Identity: 33% (84 aa) DQCLIGQTKENRRKNRYKNILPYDATRVPLGD-----EGGYINASFIKIPVGKeeFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQR .. ... .||..||||..|...| .|| | . |. |||||... .. .||.|.||..||.|||.|.|..|..|| |.|. .|||| ||.. eekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdkt--rafiatqapleetvedFWrmvwqekigviVmLtnliegekkkchq YWPNilgkTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHI--HRSGPIITHCSAGIGRSGTLI |||. .| .||. | . .. ...| ..|. ...| |.. ...|| |||. |.. ..| . . ... . . |.. |||||.||.|. . YwPd----stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaGvgRtGafl CIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL || .| . .. || . |. .| .| ||||..||.|.....| | vidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal |
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| Phosphatase | PTPN13.AA | Subfamily.N14.PD | 2221-2472 | 34 | 5.7e-63 | 203.9 | In-house | 5-273 (275) | Show / Hide |
Range on Protein: 2221-2472 Range on HMM: 5-273/275 Sequence Identity: 34% (90 aa) ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLG----DEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQE | |.... . .. .. .|| .|||.|..|||. .|| | .. |||||| ||..|| .| ||..||||..|| |||||.|||...|.|.|.| eyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmltee VEGEKIKCQRYWPNILGKT-TMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH----R------ |. | |. .|.|. | |. .. .. .. . .. ....|. . ..| | . || .| ||||. |. ....| |... . . . eedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvk --SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV |.. |||||.||.| || |... . .. . || .. .| || .||| || | |.|.. eskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvliky |
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| Phosphatase | PTPN13.AA | Subfamily.RA.PD | 2221-2470 | 35 | 7.6e-62 | 200.3 | In-house | 5-262 (266) | Show / Hide |
Range on Protein: 2221-2470 Range on HMM: 5-262/266 Sequence Identity: 35% (94 aa) ELENLQELKPL-DQCLIGQTKENRRKNRYKNILPYDATRVPLGDEG-----GYINASFIKIPVGKEEfvYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT |...| . | ... ... .||..|||. .||||| .|| | |||||||. |.. .||.|||. || |||.|||||||. | |.| efkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdk--fiaaqGpkeetvedfwrmiweqksativmlt QEVEGEKIKCQRYWPNiLGKTTmvSNRLRLALVRMQQLKGFVVRAMTLE----DIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR--SG- . | .. ||..|||. | | .|... .. |. . || . .. . ...| .. . ||.||. |... .|.. ...... .. | elkerkeekcaqywpd-eGlvt--yGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanh PIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVIL |. |||||.||.||.| .| || . . |. . |. .|||| ||||. || |.|.|.| pivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvll |
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| Phosphatase | PTPN13.AA | Subfamily.N1.PD | 2238-2470 | 39 | 2.4e-61 | 198.8 | In-house | 24-264 (268) | Show / Hide |
Range on Protein: 2238-2470 Range on HMM: 24-264/268 Sequence Identity: 39% (95 aa) QTKENRRKNRYKNILPYDATRVPLGD-EGGYINASFIKIPVGKEEfvYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTT ...||| .|||... ||| .|. | . . |||||..... | . || ||||| |.. ||||.|||.| . |. . || ..||| |||. ... klpenrglnryrdvspydhsrikleradvdyinaslveleeakrr--YiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqeeeeae MVSNR--LRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHI----HRSGPIITHCSAGIGRSGTLICIDVVL .. .. |.. |.. .. . |.|| . |||..|.|.| |.| .| ||| |. | .|.|. .|. . ||.. |||||||||||| .| .| llleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtlslvdtcl GLISQDLD---FDISDLVRCMRLQRHGMVQTEDQYIFCYQVIL .| . | ||.. . .| .|.|..|| || | |. || veiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiail |
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| Phosphatase | PTPN13.AA | Subfamily.N9.PD | 2220-2470 | 34 | 2.5e-61 | 198.8 | In-house | 4-271 (275) | Show / Hide |
Range on Protein: 2220-2470 Range on HMM: 4-271/275 Sequence Identity: 34% (93 aa) KELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGD-----EGGYINASFIKipVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT || ..... .. . | ... | .||||...| || ||| | . ||||.|.. |.. .|| ||||. || |||.|.|||.|| |.|. keyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvd--GykqkkafiatqGplkktvsdfwrmvweqevlvivmtt QEVEGEKIKCQRYWPNILGKTTMvSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHI----------- || ..||..|||. .... |... | ... . ..|| .......|.| |...| |..|||. .||. .|| ....|. rvvergrlkcgqywpleeessae-fgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde ---H-RSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVIL | . ||. ||||||||.||.| .|. | . . |. . |. .| || ..||..|| |||. .| skghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavl |
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| Phosphatase | PTPN13.AA | Subfamily.N5_RR.PD | 2242-2470 | 31 | 8.6e-61 | 196.8 | In-house | 23-261 (265) | Show / Hide |
Range on Protein: 2242-2470 Range on HMM: 23-261/265 Sequence Identity: 31% (76 aa) NRRKNRYKNILPYDATRVPL------GDEGGYINASFIKIPVGKeEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGK- . .|||||.||| . .|| | .. |||| .|| . .. . .|.| |||||.|. |||.||......|| |.|. | .. ||..|.|. . sqtknryktilPnensrvllesessededssyinanyikGydee-skayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedye TTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTrEVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR-----HIHRSGPIITHCSAGIGRSGTLICIDVV . . . . . . . ... || ..|. . |.. | .|.||||..| ... || .. .. . .. .|.. |||||||| | |.|.. iserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisia LGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVIL . . .. |. .| .||.| |||||..|| . .... vrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc |
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| Phosphatase | PTPN13.AA | Subfamily.N_Choan_2.PD | 2236-2470 | 33 | 1.5e-60 | 195.8 | In-house | 15-262 (266) | Show / Hide |
Range on Protein: 2236-2470 Range on HMM: 15-262/266 Sequence Identity: 33% (84 aa) IGQTKENRRKNRYKNILPYDATRVPLGD-----EGGYINASFIKIPVGKEEFvYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPN | .. |.| |||..||| |||| | . . |||| ... |... ||| .||||||. .||.||||.|.| |.|.|..| . ||.||||. iPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkk-YiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpa ILGKTTMV-SNRLRLALVRMQQLKGFVVRAMTLEDiqTREVRHISHLNFTAWPDHDTPSQPD------DLLTFISYMRHIHR----SGPIITHCSAGIGR .... . . .. . . .. .|.... ..|| |.|.. | ...|||| |...| .||. . .|.... ..|...|||||.||. epkekvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgR SGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVIL |||| || .. |.... |. ... .| .| .||. .|| . |.... tGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavv |
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| Phosphatase | PTPN13.AA | Subfamily.RK.PD | 2232-2472 | 36 | 2e-60 | 195.4 | In-house | 19-265 (267) | Show / Hide |
Range on Protein: 2232-2472 Range on HMM: 19-265/267 Sequence Identity: 36% (89 aa) DQCLIGQTKENRRKNRYKNILPYDATRVPL----GDEGGYINASFIkiPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQE-VEGEKIKCQR ..| |.. ..||.|||...||.|| ..| | ||. ||||..| | .|. ||||. || |||......... | |.|. ||..|| .|| edcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaali--dsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClk YWPNilgKTTMVSNRLRLALVRMQQLKGFVVRAMTLED--IQTREVRHISHLNFTAWPDH-DTPSQPDDLLTFISYMRHIHRS---GPIITHCSAGIGRS |. .|.. . ... ||... .. .||| ...| . |.| . ...|..||.. |.| . ||..| . . .|.|. ||.|| ||||| | || yWPe---dtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrs GTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV .|| .| .. |. |. .| .. ||.||.||.|.|.||| Gtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvilea |
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| Phosphatase | PTPN13.AA | Subfamily.RG.PD | 2220-2472 | 31 | 1.2e-58 | 189.8 | In-house | 4-262 (264) | Show / Hide |
Range on Protein: 2220-2472 Range on HMM: 4-262/264 Sequence Identity: 31% (83 aa) KELENLQELKPLD-QCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG-----YINASFIKIPVGKEEfvYIACQGPLPTTVGDFWQMIWEQKSTVIAMM .. |..|.||| | .. . .||..|||. ||.... .||.| . | |||||.|. ..| ||. ||||..|. |||.||||.....| |. eqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrske--yivtqgplketiedFWrmiWehnaqiivml TQEVEGEKIKCQRYWPNIlgKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRH--ISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRS--GPI |. .| . ....|||. .... ...|.. |.. ..|. ..|| ..|..... .... . ....| |||...|.. . |.|. . ... ||| tdldekgrrdedvyWPkk--deplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPi ITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV . |.||| ||.||.| .| .| . . .. .... .|..| |.|.||.||.| |...| . vvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel |
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| Phosphatase | PTPN13.AA | Subfamily.N23.PD | 2236-2471 | 33 | 9.6e-57 | 183.8 | In-house | 103-347 (350) | Show / Hide |
Range on Protein: 2236-2471 Range on HMM: 103-347/350 Sequence Identity: 33% (81 aa) IGQTKENRRKNRYKNILPYDATRVPlGDEGGYINASFIKIpVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKT || .... . .| .. . . | | . ||||...| . .|| |||...|..|||.|.|||.| || |.|.||||.| ||..|||. |.|. sGqqqgtpdsrhdpnrvklqqstqp-gqqddyinatylke-ltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPideget TMVSNrLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH------R-----SGPIITHCSAGIGRSGTLI . . ||..| .... .|.. | ..|. ... ||...||..|.|... |. |.||| |. ..... .||| |||||.||.||. .. .. nlfgd-lrvslkslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfc CIDVVLGLIS-QDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILY .. .. .| ..|| .| ||. |||..... ..|...| vvysaireltagngiiniprvvrrlrqqRkymvqkkvilkklyeavle |
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| Phosphatase | PTPN13.AA | Subfamily.R_Ecdysozoa.PD | 2221-2470 | 32 | 1.2e-56 | 183.0 | In-house | 5-265 (269) | Show / Hide |
Range on Protein: 2221-2470 Range on HMM: 5-265/269 Sequence Identity: 32% (85 aa) ELENLQ-ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLG-----DEGGYINASFIKipVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT | |.|. .|. .. ... ||| ||||..| ..| ||| | .. |||||||| ||.. .|| |.|. .|.||||.||.||..|.| |.. eyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfik--gykekkkfiaaqdPveatigDfWrmiaeqevtlivmls QEVEGEKIkCQRYWPNIlgkTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQ---TREVRHISHLNFTAWP-DHDTPSQPDDLLTFISYMRHIHRS---- .. | .. |..|||. ... . . ||. .. . .. |.... .. . |.. ..|.|. | | .. || .|. .|.... nlteknrk-cakyWpie---devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnkls ---GPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVIL .||. ||||| ||||.....|..| . .. || . |. .| ||.|| .||.|.|. .. gsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyrala |
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| Phosphatase | PTPN13.AA | Subfamily.RC.PD | 2235-2470 | 30 | 5.1e-52 | 168.1 | In-house | 19-284 (288) | Show / Hide |
Range on Protein: 2235-2470 Range on HMM: 19-284/288 Sequence Identity: 30% (82 aa) LIGQTKENRRKNRYKNILPYDATRVPL-----------------------GDEG-GYINASFIKipVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVI |.. .||. |||| ..|||| ||.| ..|| |||||||. |. .||| |||| ||.|||.||.|.| .|| kiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfid--sykkpekyiaaqGplketvddfwrmiferkvkvi AMMTQEVEGEKIKCQRYWpnilGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISY----------- |.|. ||.. || .|| .. . . . | .. ...| . | . . .. |.. ....|.|.... | .| ||.| vmltelkeGdrekcaeyw----eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrss -MRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVIL . . |.|.. ||..| .|.|. |... .| . . |. ..|. .| .| .||..|.|||. |.|. eafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlv |
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| Phosphatase | PTPN13.AA | Subfamily.RN.PD | 2234-2469 | 36 | 2e-51 | 166.0 | In-house | 19-259 (264) | Show / Hide |
Range on Protein: 2234-2469 Range on HMM: 19-259/264 Sequence Identity: 36% (88 aa) CLIGQTKENRRKNRYKNILPYDATRVPLGDE-----GGYINASFIKiPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW . ......| .|||.|..|||| .|| | .| |||||.| . .|||.||||..|. |||||.||| ..|| ..|. | ..|.||||. kevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasail-dhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckryw PNIlGKTTMVSnrLRLALVRMQ-QLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH--RSGPIITHCSAGIGRSGTLIC |. . . || . ..||.. | ..||.| | .. . | .||....|... || | . . || ||. |||.| ||.|. | || pde-Gsevyhi--yevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyil IDVVLGLISQDL-DFDISDLVRCMRLQRHGMVQTEDQYIFCYQVI .|| . . . . ||. . .| ||.|.|.|.||. |..... idlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltav |
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| Phosphatase | PTPN13.AA | Subfamily.N_Nematode_4.PD | 2231-2470 | 28 | 7.2e-50 | 161.0 | In-house | 15-260 (264) | Show / Hide |
Range on Protein: 2231-2470 Range on HMM: 15-260/264 Sequence Identity: 28% (70 aa) LDQCLIGQTKENRRKNRYKNILPYDATRVPLGDE---GGYINASFIKIPvgkEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRY .. ...| ||||..|| |.||| | . || ||....| ..| ||..||||. |. ||| |....| .|. |. . .|.. ||.||.| ppnvtasaseknsdknryadilcidetrvvlknrdpdndyihaswmrmP---dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcary WPNILGKTTMV-SNRLRLALVRMQQLKGFVVRAMTLEDIQ-TR----EVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSG . ..|.. . . |..| . . . . ....... .. .. | . |.... |.|..| .. .. .. .... ....||. |||||.||. ||. ypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkkekPivvhcsaGvGrta TLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVIL || | . . .. |.|| .| | . ||.. |..| .|.. tlvGidyatirirenseievldivrelramrlkavqshlqflfllvvli |
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| Phosphatase | PTPN13.AA | Subfamily.N_Nematode_1.PD | 2221-2470 | 29 | 2e-44 | 143.1 | In-house | 5-261 (265) | Show / Hide |
Range on Protein: 2221-2470 Range on HMM: 5-261/265 Sequence Identity: 29% (76 aa) ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPL---GDEGGYINASFIKIPVGKEEFvyIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEV |...|.. .. .. ...... |||||.. | .|| | . || | .. .|. | | .|.|| |. ||||. .| | |. . .| efralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnpkrf--icaqaPldktiadfwymvlqekveaivmlckli EGEKIKCQRYWPNILGKTTMVSNRLRLALV-------RMQQLKGfVVRAMTLE-DIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHihRSGPI |.||. |.| |... .... . | ... . |... .|| . ...|..|...| |||. |. | ... .|. |||. ekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedee-vikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrg--skgPi ITHCSAGIGRSGTLICIDVVLGLISQDLD-FDISDLVRCMRLQRHGMVQTEDQYIFCYQVIL ||||||||.||.. |. .| . .. |...||. .| ||..||. ||.| ..|.| vvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvll |
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| Phosphatase | PTPN13.AA | Subfamily.N_Nematode_6.PD | 2241-2472 | 30 | 2.1e-42 | 136.6 | In-house | 23-251 (253) | Show / Hide |
Range on Protein: 2241-2472
Range on HMM: 23-251/253
Sequence Identity: 30% (69 aa)
ENRRKNRYKNILPYDATRVPLG-DEGGYINASFIKIPVGKEEFvyIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVS
... .|||.|| .||.|. | || || |...|| .. . | .|.|| .|. .||.|| . .. | |. . || ||. .| ....|... ...
kfkdrnrytniqCcdagrlkladdedfyihanlvkistkprrl--ictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarkit
NRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRsgPIITHCSAGIGRSGTLICIDVVLGLISQDLDF
. .. .||.. .. | . |... .|||| | . . | ..| ..... ||. |||||.|| |||. | ..| . . ..
klctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk--PivvhCsaGvGrtGtlaliliilealrlpdfq
DISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV
||. .| .| |||| ||.. .. .|
gvkdllvklreerfravqtevqylyalrcvley
|
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| Phosphatase | PTPN13.AA | PTPc_motif | 2372-2471 | 43 | 2e-41 | 144.87 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 2372-2471 Range on HMM: 1-92/92 Sequence Identity: 43% (46 aa) HISHLNFTAWPDH-----DTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCY . |. .|.|||| .|. |..|.|| ..|. ||. |||||.||.||...||... . .|| ..|. || ||.||||||.|||||| TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-----PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIFCY QVILY ..||. RCILE |
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| Phosphatase | PTPN13.AA | Subfamily.R_Nematode_2.PD | 2242-2473 | 27 | 2.4e-41 | 132.9 | In-house | 29-260 (261) | Show / Hide |
Range on Protein: 2242-2473 Range on HMM: 29-260/261 Sequence Identity: 27% (64 aa) NRRKNRYKNILPYDATRVPLGDEGGY--INASFIKIpvGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVS .. |.||... . |.| .| | | .. ... .|| |||| |. ||| |. .| | |..| || ||.||..|.| .... . pkdkhRypdvPCkpetavevivdgkrvpihanwvpt--agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlg nRLRLALVRMQQLKGF--VVRAMTLEDIQT-REVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRsgPIITHCSAGIGRSGTLICIDVVLGLISQD |.... | .... .|.. || . . | . |. .. |||...| ..| .. ... .. ||. ||||||||....| .... . .| -rfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek--PivvhCsaGiGRtmafigteylarevead LDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL . ...... .| .| .||| |. . . || | ptieltealkelrehRwkgiqtesqlywltlgalyrl |
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| Phosphatase | PTPN13.AA | Subfamily.R_Nematode_3.PD | 2237-2472 | 23 | 7.7e-39 | 124.8 | In-house | 18-265 (267) | Show / Hide |
Range on Protein: 2237-2472 Range on HMM: 18-265/267 Sequence Identity: 23% (59 aa) GQTKENRRKNRYKNILPYDATRVPLGD-----EGGYINASFIKIPVGKEefvYIACQGPL--------PTTVGDFWQMIWEQKSTVIAMMTQEVE---GE ..... ..|..... . .||| | . . ..|.|.....| | . | |.|. .|. ||.|| ..|.....|. . || .|. tslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpnglk---lIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgee KIKCQRYWPNILGKTTMVSN-RLRLALVRMQQLKGFVVRAMTLeDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHrsGPIITHCSAGIGR || .|.|. .. . . .. . .. .... | ... .. .. ..|| ...|... .| .|. .| | .... |.. |||.||.|| eekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk--tpvvVHCsdGisR SGTLICIDVVLGLISQDL-DFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV .|| .|... ||.. ..|. .|. .| ||.| .||| ...|.|| . satlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkl |
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| Phosphatase | PTPN13.AA | Subfamily.N_Nematode_5.PD | 2220-2471 | 24 | 7.4e-34 | 108.3 | In-house | 4-255 (258) | Show / Hide |
Range on Protein: 2220-2471 Range on HMM: 4-255/258 Sequence Identity: 24% (63 aa) KELENLQELKPLDQcLIGQTKENRRKNRYKNILPYDATRVPLGD-EGGYINASFIKIPVGKEefVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVE .| |.|..||| . . ..| |||.|.. .|.||| |.| . .||||| ||.. .. .| | |||.|. |||.|. ..| | . ..... | tefeklaslkpnke-tckafeknlkknrskdvkilDetrVkltdeddsYinaskiklddlek--kliltQlPlpdteedFWrmvyqekitsvvllvedee GEKIKCqRYWPNILGK-----TTMVSNRLRLALVRMQqlKGFVVRAMTleDIQTREvRHISHLNFTAWPDHDTPSQPDDLLT--FISYMRHI-HRSGPII .. .. ..|. |. . .. || ... | ..| . . . . ... ..| |... |.. .... ..... .. |.. lketav-sffpletgdylnlgkmfinnrkvevkedek--keytvevlp--egcses-vfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvv THCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILY ....|.||.||.. ..|. . .. ..|..... .| || |.|.. .|| . |...|. vvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavld |
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| Phosphatase | PTPN13.AA | Subfamily.N_Fungi_PTP1.PD | 2232-2331 | 39 | 5.6e-24 | 75.9 | In-house | 35-151 (343) | Show / Hide |
Range on Protein: 2232-2331 Range on HMM: 35-151/343 Sequence Identity: 39% (45 aa) DQCLIGQTKENRRKNRYKNILPYDATRVPLG-------------DEGGYINASFIKIP----VGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT |. .| | ||||||||||. .|| | ||||...|.. . .| ||| |.||| ||||...| . | .|| ..|. ddviissGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilslt QEVEGEKIKCQRYWPNI .|| . ||.|||.. sdvelnlekcyrYWqeg |
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| Phosphatase | PTPN13.AA | Subfamily.N_Nematode_egg.PD | 2239-2472 | 25 | 3.8e-23 | 73.4 | In-house | 23-255 (257) | Show / Hide |
Range on Protein: 2239-2472 Range on HMM: 23-255/257 Sequence Identity: 25% (59 aa) TKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPV--GKEEF-VYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEkiKCQRYWPNILGKT ..... | | | . . .|| | . | ||. || . .| .| || || |||.|....| | |.|.| | .|. |||. .. . sdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakese--rceyywpkaeses TM-VSNRLRLALVRMQQLKGFVVRAMTLEDIQ-TREVRHISHLNFtawpDHDTPSQPDDLLTFISYMRHIhrSGPIITHCSAGIGRSGTLICIDVVLG-L | ||. ..... . | | . .| ... | . | . |.| . .|.. | |.. .. |. ...||..|.. | |. lvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwqg----dvnylsdvysplrvlrklrnl--skpvvvqdilGvskaatlvaieiallsl ISQ-DLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV . . | .||.|. |.. .|.| |...|. lrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlff |
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| Phosphatase | PTPN13.AA | Subfamily.N_Nematode_eak.PD | 2223-2471 | 22 | 1.8e-18 | 58.0 | In-house | 7-278 (281) | Show / Hide |
Range on Protein: 2223-2471 Range on HMM: 7-278/281 Sequence Identity: 22% (63 aa) ENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLG----DEGGYINASFIKIP-VGKEefvYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEV ..|.. ..| .. |. ..|| .|.|.| | | .. |||||| .. . ||.. || . . |||||. |||| | .. ..|| adlddyqrllsirvtarleavnrnrvvkivpqdrylvrltssqlnrdGyinaslaefsevGrk---yiltGiasedkvfafwqmvleqkspaivqlledv EGEKIKCQRYWPNILGKTTMvsNRLRLAlvRMQQ-LKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLL-------------------TFI . | ..|.|. . | . | . .| ... |. . | .. |.. | . ..| | | . |.. eekleksdkyfpdktevlky--Gildve--rkeyavkrniletrllilrkGnethrvlhykvfGwtettlpkyedflalrkvmkevGvlllivmksallr SYMRHIHRSGPI---ITHCSAGIGRSGTLICIDVVLGLISQDL--DFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILY .. . . | | .. | |.|... ||... ||. . . ||. .. .| | .. |. | |...| stlkkyihtppsfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivld |
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| Phosphatase | PTPN13.AA | Subfamily.N_Fungi_PTP1.PD | 2368-2472 | 32 | 2.6e-15 | 47.4 | In-house | 210-341 (343) | Show / Hide |
Range on Protein: 2368-2472 Range on HMM: 210-341/343 Sequence Identity: 32% (40 aa) REVRHISHLNFTAWPDHDTPSQPDDLLTFIS--------YMRH----IHRSGPIITHCSAGIGRSGTLICIDVVLG---L---I---SQDLDF------D |. . .|.. |.| . .| ..|. . . . || ||. |||||.|| |||. .| .|. |. || || .| .| sepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDl ISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV || |||. ||.||.|. .|. isiivnelrkqrismvqnldqfifiYeallfy |
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| Phosphatase | PTPN13.AA | Family.DSP.PD | 2370-2469 | 24 | 2.6e-10 | 31.4 | In-house | 149-241 (387) | Show / Hide |
Range on Protein: 2370-2469 Range on HMM: 149-241/387 Sequence Identity: 24% (25 aa) VRHISHLNFtAWPDHDTPSQPDdLltFISYMRHIHR----SGPIITHCSAGIGRSGTLICIDVVLGlisqdLDFDISDLVRCMRLQRHGMVQTEDQyiFC .| .|.. ...|| .|. | |.. .. |. .| . || ||.|||||||.. . .. .. .. .| .| |... ... | | elgikylri-pidDhnapplen-l--fekaidfieegndskgvVlVHCkaGkgRsgtliiaYlmks-----egltleealdwvrskRpgvitpnqg--fl YQVI . kqlk |
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| Phosphatase | PTPN13.AA | Subfamily.PTPDC1.PD | 2371-2471 | 24 | 4.2e-10 | 30.7 | In-house | 133-226 (229) | Show / Hide |
Range on Protein: 2371-2471 Range on HMM: 133-226/229 Sequence Identity: 24% (24 aa) RHISHLNFtAWPDHDTPSqPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLgliSQdlDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVIL . | . || ...|....| . .|. . . . | | || || || | ||. .| .. ... .. .. .| .| .||.| .. . |. qgiyfynf-glkDygvas-leriLdivkvvdfaleegkiavHCHAGlGRtGvliacylvy---ak--rltaeeaiklvrskrpksiqtreqvelveeFal Y f |
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| Phosphatase | PTPN13.AA | Subfamily.CDC14.PD | 2393-2462 | 28 | 1.7e-06 | 19.1 | In-house | 187-249 (258) | Show / Hide |
Range on Protein: 2393-2462 Range on HMM: 187-249/258 Sequence Identity: 28% (20 aa) LLTFISYMRHIhrSGPIITHCSAGIGRSGTLICIDVVlglisQDLDFDISDLVRCMRLQRHGMVQTEDQY | |.. . .. .| |. || ||.|| |||| .. . | .. . .|. | |.| . | lkkfleiteka--eGaiavhCkaGLGrtgtligcyli-----khyrftaaetiawlriarPGsvigpqqt |
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