Gene PTPN14
PTPN14
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTPN14.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| FERM | PTPN14.AA | B41 | 17-220 | 26 | 6.3e-68 | 232.89 | SMART | 1-232 (232) | Show / Hide |
Range on Protein: 17-220 Range on HMM: 1-232/232 Sequence Identity: 26% (62 aa) SKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLEL--RETHYFGLWFLSKSQQARWVELEKPLKKHLDK--FANEPLLFFGVMFYVPN----VSW |. ... |....|. ..|... ..|||. ...|...... ||..|||||. .. .. .| ...|...|. | ... |.| | ||.|. ... SPKPRFCRVYFMDGTTLEFEVDSSTTGQDLCDHVCRHCGISPREHWYFGLWYEDPHEDRHWLDHWKTIMKQDVKWHKSEPWTLHFRVKFYPPDWHGFPNQ LQQEATRY-QYYLQVKKDVLEGRLRCT-LDQVIRLAGLAVQADFGDYNQF---------DSQDFLREYVLFPMDLALEEAV--------LEELTQKVAQE ||...||| ..|||...|.|.||. |. . ..|| |.||...|||.. . | ..... ..| ... .... ..|........ LQEDPTRYNYFYLQCRHDILQGRHPCPHEEECLQLAALQVQIEYGDYDPEETNNKKMTKHVQKYKSYKRFLPKQWIDSIKQSFMHYQMHHKEWRKRIMEW HKAHSGILPAEAELMYINEVERLD-GFGQEIF || |.| |.||.|.|.. ..|.. ..| | | HKNHCGMTPEEAKLKYLQICQRWPPMYGVEHF |
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| FERM | PTPN14.AA | FERM_M | 105-220 | 22 | 4.8e-38 | 131.73 | Pfam | 1-171 (171) | Show / Hide |
Range on Protein: 105-220
Range on HMM: 1-171/171
Sequence Identity: 22% (38 aa)
NVSW-LQQEATRYQYYLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFG-DYN-QFDSQD---FLRE------------------YVLFPM----------
... .|.|.||.|.|||.| |.||||. |. .. . ||....|..|| ||| .... . . . . ..|.
DPNRDIQDEVTRHQFYLQAKWDILEGRYPCSEEEALMLAAYQCQIEFGSDYNPPQKHKSDYMEKEWWEQQEGMEVWLRCDNEQQERYWPAHCRLASKGRT
--------------------DLALEEAVLEELTQKVAQEHKAHSGI-LPAEAELMYINEVERLDGFGQEIF
..... .....|.....||.|.| |.||.|.||....|....| . |
MADSSYSEVSIRINPHCYVSPWYCKKMKQKQWEQRILEQHKNHRGMCSPEEAMLQYIQICQRWPMYGVHFF
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| FERM | PTPN14.AA | FERM_N | 25-103 | 33 | 2.6e-32 | 118.46 | Pfam | 1-93 (93) | Show / Hide |
Range on Protein: 25-103 Range on HMM: 1-93/93 Sequence Identity: 33% (31 aa) IRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWF---LSKS--QQA-RWVELEKPLKKHLDK--------FANEPLLFFGVMFYV ..|||. ..|||. ...||||....|.|.|..||..||||.| |. .| .|....|...|.... . . ..||| |.||. VHLLDDTQLECTCDKKTTGQELFDQVCQHLNIRECWYFGLQFCKQNDKKEGNQHMHWLDPDKKICKQMKDGWKHKIKKKCPPCTLFFRVKFYP |
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| FERM_C | PTPN14.AA | FERM_C | 224-306 | 17 | 2.1e-08 | 32.28 | Pfam | 1-95 (99) | Show / Hide |
Range on Protein: 224-306 Range on HMM: 1-95/99 Sequence Identity: 17% (17 aa) DNHGNC-VHLGIFFMGIFVR--NRIGRQ--AVIYRWNDMGNITHNKSTILVELI-------NKEETALFHTDDIENAKYISRLFATRHKFYKQNK |..|. ..||. .|| | . . . ..|.. ..|..........| ..|.| |.... ...||. .. |.|... . DKKGTDTWWLGVCAKGINVYQVQDNNKITPMNTFPWPEIRKISFKRKKFFIKLRDDPDEGEKYEHTHTFYMPNYRACKYLWKCCVEHHQFFRLRR |
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| Phosphatase | PTPN14.AA | Subfamily.N14.PD | 908-1182 | 66 | 8.20000000001e-152 | 495.4 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 908-1182 Range on HMM: 1-275/275 Sequence Identity: 66% (182 aa) MVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAM .||||||.||||......|||.||||||..|...|.|||.|||||.|||||.|||||||.|||.|||.|..||..||||..|..|||||||||||..|.| kvfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivm VTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSML .|.|||.|..||..|.|||.||......|||||||||..|| ...|||||.|||.|..||||||||||||||||.||||.||||.|||.|||||.|||. lteeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsev EGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQ |..|...||..||||||||||||||||.|.|..|||||.......|. ||.|||...||.|||||||.|||..|. esvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikylk |
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| Phosphatase | PTPN14.AA | PTPc | 908-1182 | 29 | 1.3e-107 | 364.7 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 908-1182 Range on HMM: 1-308/308 Sequence Identity: 29% (95 aa) MVFTEYEQIPKKKANG---------IFSTAALPENA--ERSRIR-EVVPYEENRVELIPTKE-----NNTGYINASHIKVVVGGAEWHYIATQGPLPHTC ....|.| ... . . ...|..|||. .. | . ...|...|| | |... ....||||..|.. . . ||.||||||||. GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPLPHTI HDFWQMVWEQGVNVIAMVTAEEEG--------GRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSV-CYATTGLKVKHLLS--------GQERTVWHLQ |||.|||.|.. .|.| . ..|. || | |.||| . |||...||.| . .| .. ..|.. ...|||.|.. EDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-----PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYH YTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGT----------KNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFM ||.|||||.||. ..||...... ....| . | . . ...|||||||||.||||.... . |. ..|. | .. ... .|.||..| YTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYM-NMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGM IQTIAQYKFVYQVLIQFLQ .|| .||.|.|........ VQTEEQYIFCYRCILEYIK |
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| Phosphatase | PTPN14.AA | Y_phosphatase | 933-1179 | 35 | 1.8e-104 | 358.16 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 933-1179 Range on HMM: 1-243/243 Sequence Identity: 35% (90 aa) NAERSRIREVVPYEENRVELIPT-KENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGR-TK-SHRYWPKLGSK | |. | . ...|. .|| | |. .... ||||..|.. ... .. ||.||||.|||. |||.|||.|.. .|.|.. ..|.|| | |.||| . NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG-PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPD-NKE HSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLS--GQERTVWHLQYTDWPDHGCPED-VQGFLSYLEEIQSVRRHTNSMLEGTKNRHP--PIVVHCSAG . . |||.|.||.. . .| .. ..|.. . ...|||.|..||.|||||.||. ....|........... ...|. ||||||||| GQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP---------NPDHGCPPIVVHCSAG VGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQ .||||.... . |. ..||...|... ... .|.||..|.|| .||.|.||.... CGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | PTPN14.AA | Subfamily.N3.PD | 909-1179 | 38 | 2e-79 | 257.8 | In-house | 2-258 (261) | Show / Hide |
Range on Protein: 909-1179
Range on HMM: 2-258/261
Sequence Identity: 38% (105 aa)
VFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELiptKENNTGYINASHIKVVVGGAE--WHYIATQGPLPHTCHDFWQMVWEQGVNVIA
| ...|.. .|| . |.| .|||... | |...||.. ||.| ||..| ||||..... . ... .||||||||..|..||||||||| ...|
vlaqfeelyrkkpglaisaarkpenlaknryrdilpydatrvkl---kesetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstliv
MVTAEEEGGRTKSHRYWPKlgsKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRrhtnsm
|.| | ||.| |.|||. .. . ..|.|.|. . . . | . | .|. . .||.. .|||..||||| |.| . ||...|.....|
mlttlverGrvkChqyWPe---tedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr------
legtKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQ
. ...|.|||||||.|||||||| |. . .|..|.| .. ..| .|.||. ..|| .||||| . ...
----sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailk
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| Phosphatase | PTPN14.AA | Subfamily.N13.PD | 912-1181 | 39 | 3.4e-74 | 240.9 | In-house | 5-258 (259) | Show / Hide |
Range on Protein: 912-1181 Range on HMM: 5-258/259 Sequence Identity: 39% (107 aa) EYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELiptkENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAE |.... . |. ... || .. | |.|.||.| ||.| ....||||||.||| || |..|||.|||||.|..||||||||| ..|||||| | efkelrelkpldtcevgkkkenkdknryrnvlPydetrvkl----gdeggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtle EEGGRTKSHRYWPKLGSKHSsATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRhtNSMlegtk |.|. | |||||. .|. .....|. .. .. |.||.. ||. | | ||....||||| | . .. ..|...... .. kekgkvkchrywPerknkkl-kvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt--dag----- nrhpPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL |||||||||.||.|||| . .. .|......| ..| ||||| ..|| || |||..... | ----PivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl |
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| Phosphatase | PTPN14.AA | Subfamily.N_Choan_1.PD | 911-1181 | 36 | 2.8e-70 | 228.1 | In-house | 4-261 (262) | Show / Hide |
Range on Protein: 911-1181
Range on HMM: 4-261/262
Sequence Identity: 36% (99 aa)
TEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKE-NNTGYINASHIKVVVGGAEwhYIATQGPLPHTCHDFWQMVWEQGVNVIAMVT
.|||.. . . . . .|| .. | . .| |. ||.. |..| .|| ||||.... . | .| |||||||.|.....|||||||| |..|.|||
eeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgeke--yiatqgPvPaslvsfWqmvweqkvsaivmvt
AEEEGGRTKSHRYWPklgSKHSSATYGKFKVTTKFRTDSVCYATTGLKVkHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSmleg
.| |.|. | ||||| ..|. ..|...|... .... |.. .|. . ||..|.| .|.|| ||||| |.. . .|.. ......... .
reieagklkChryWP---denselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk----
tknrhPPIVVHCSAGVGRTGVLI-LSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL
|.|.||||||||||. | | |. . |..|...| ... ||..|..|.||..||.|||... . |
-----aplvihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal
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| Phosphatase | PTPN14.AA | Subfamily.R_Anemone_2.PD | 909-1181 | 38 | 7.1e-69 | 223.6 | In-house | 2-261 (262) | Show / Hide |
Range on Protein: 909-1181 Range on HMM: 2-261/262 Sequence Identity: 38% (103 aa) VFTEYEQI-PKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKE-NNTGYINASHIKVVVggAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIA ...|||.. .... . ...| | |. . | ....|.. ||.| .... ... ||||..| .. |||||.|||.|..|||.|||||. || lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyr--rkkayiatqaPlpetiedfWrmvWeqnsaviv MVTAEEEGGRTKSHRYWPKLGSKhssaTYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRhtnsm |.| ||| |..| |||||. ||. .||| .|. | .... | .|||. . .||.|.||.|||.| ||.. ..|. . ..... . mltqeeergkakvhryWPskgsr----sygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqq----- legtKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL .. . ||||||||||||||| | . .. ..... |.| ...||||| |.|| ||.|.|.||...| ----esgagpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal |
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| Phosphatase | PTPN14.AA | Subfamily.N9.PD | 910-1180 | 37 | 8.4e-68 | 220.1 | In-house | 3-273 (275) | Show / Hide |
Range on Protein: 910-1180 Range on HMM: 3-273/275 Sequence Identity: 37% (101 aa) FTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKEN-NTGYINASHIKVVVggAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMV ||..| .....| | .. |. | |. | .|. |.| || | ..|. .. ||||.... . .|||||||..|..|||.|||||| || |.| skeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGyk--qkkafiatqGplkktvsdfwrmvweqevlvivmt TAEEEGGRTKSHRYWPKlgSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLE .| || | .|||. ...||| .|...|.. . | .. |..|. ....|.| | |.. |||.| |.. . .|||.... . . . | . trvvergrlkcgqywpl--eeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelg GT---KNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQF . . ||||||||||.|||| .| .. . ||. ..|.| ..|||.|| |.||| ||.| |. .... deskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley |
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| Phosphatase | PTPN14.AA | Subfamily.RB.PD | 911-1182 | 34 | 3.1e-67 | 218.0 | In-house | 4-261 (261) | Show / Hide |
Range on Protein: 911-1182 Range on HMM: 4-261/261 Sequence Identity: 34% (93 aa) TEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTK-ENNTGYINASHIKVVVGgaEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVT |||.. | . . ..| ...| .. | ....||...||.| .| |..| ||||..|. . .|||||||||.| .|||.||||....| |.| eeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgyns--preyiatqGPlpetvddfWrmvwekkssiivmlt AEEEGGRTKSHRYWPKlgsKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHllSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTnsmleg |.|..| ..|||. .... .||. ||| . .. ... .|... ..|.| ....| ||||| ||. . |........ ... qlvEkgkekceeYWPa---deepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekk------ tkNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQ . ||||||||||||||. | . .. .|.|. |.| .. |||.|....|| .|| |....|...|. --askkPivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldlle |
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| Phosphatase | PTPN14.AA | Subfamily.R_Sponge_2.PD | 913-1181 | 34 | 1.4e-64 | 209.4 | In-house | 5-261 (262) | Show / Hide |
Range on Protein: 913-1181 Range on HMM: 5-261/262 Sequence Identity: 34% (92 aa) YEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVggAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEE |. .|. .. .|.| |.|| ..| .|..||...||.| ....... |||||.. . . ||||||||..| .||| ||||. |. | |.| || eeksveketefslsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgyk--rrkayiatqgPlketveDfWRmvweykvstivmltnle EGGRTKSHRYWPKlgSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLS-GQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQsvRRHTnsmlegtK |. |...|||. .. ...||||||| | .. .. |.. ||... | ..|..| . ... ||.|..|.| .|. ..... | .. |. engkekcakYWPe--kvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvl--raqk-------k NRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL . .|.|.||.|||||| | . .. |...|...| .|. || .|....|..|||.|....| ... sgnkaitvvCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi |
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| Phosphatase | PTPN14.AA | Subfamily.N6.PD | 909-1181 | 30 | 8.7e-63 | 203.6 | In-house | 14-294 (295) | Show / Hide |
Range on Protein: 909-1181 Range on HMM: 14-294/295 Sequence Identity: 30% (89 aa) VFTEYEQIPKKKANGIF--STAALPENAERSRIREVVPYEENRVELIPTKENNTG--YINASHI--------KVVVGGAE---WHYIATQGPLPHTCHDF . .|.|.. |.... . . .. .||.| | ....|....|| | .... .| ||||..| . . ..| .||||||.|..| .|| fweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdF WQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSsatYGKFKVTTKFRTDSVCYATTGLKVKHL-LSGQERTVWHLQYTDWPDHGCPEDVQGFLSY |.|||.. .|| |.| | | |. | ||||. ..|.. .|. .||. . | ..|.| ..|........|||||.|.| . .|..| WrmvwqensrvivmttkevergknkCarYWPdeetkke---tGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnf LEEIQSVRRHTnsmlegtkNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNE---KVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL |.... ... ... |||||||||.|||| .|. . .. .|.. .... .... .|.|| ..|| |||||||... ... ledvnkkqeel--------ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyi |
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| Phosphatase | PTPN14.AA | Subfamily.N12.PD | 919-1181 | 35 | 1.9e-62 | 202.2 | In-house | 16-269 (270) | Show / Hide |
Range on Protein: 919-1181 Range on HMM: 16-269/270 Sequence Identity: 35% (96 aa) KKANGIFST--AALPENAERSRIREVVPYEENRVELIPTKENN-TGYINASHIKVVVGgaEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGG ||. ..|| . .|| .. | ....||...|||| ..|.. .||||..|| | | . .|||.|||||.| .|||.|.||. |...|. | | |.. ykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgveg--kleyiaaqgPLpktlddfWrmiweknveivvmaCrevelg RTKSHRYWPKLGSkhSSATYGKFKVTTKFRTDSV-CYATTGLKVKHLlsGQERTVWHLQYTDWPDHGCPEDVQGFLSYleeIQSVRRHTNsmlegtkNRH | .||||. | .. ..|.|.||.. . |||.. ...|.| ..||.|||||.|. .. |. |..||.. . . . | kkkCeryWpeege--eelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllel---ielvrelqe-------sed PPIVVHCSAGVGRTGVLILSELMIYCLEHN---EKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL .||||||||||||..| ... |... |...| .. ||.|| ..|| ||..||. ..... aPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv |
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| Phosphatase | PTPN14.AA | Subfamily.N_Choan_2.PD | 926-1181 | 36 | 1.3e-61 | 199.4 | In-house | 11-265 (266) | Show / Hide |
Range on Protein: 926-1181 Range on HMM: 11-265/266 Sequence Identity: 36% (93 aa) STAALPENAER---SRIREVVPYEENRVELIPTKEN-NTGYINASHIKVVvGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHR |. |.|| | | ....| . || | . .|. .| |||| ... . |.. .|||..|||| | ..||.|.||. |. |.|.| || ||.| | seeaiPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGf-dgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCer YWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHllSGQERTVWHLQYTDWPDHGCPEDVQGFLSY---LEEIQSVRRHTNSmlegTKNRHpPIV |||. .. . ..|| ||.. . . | .| |.... .|..|.. | .|..||||| |.. .. |||. .. |||... ... . |..|||| YWpaepkekvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrke----ldkae-Pll VHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL |||||||.||. . .. .||...||.| ... ||..|| ..|. ||...|...... vHcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya |
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| Phosphatase | PTPN14.AA | Subfamily.R_Anemone_1.PD | 911-1181 | 29 | 6.8e-60 | 194.2 | In-house | 4-257 (258) | Show / Hide |
Range on Protein: 911-1181 Range on HMM: 4-257/258 Sequence Identity: 29% (81 aa) TEYEQIPKKKANgIFSTAALPENAERSRIREVVPYEENRVELIP-TKENNTGYINASHIKVVVGGaeWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVT .|.... ..|.. ..| .|| .. | ..|.... || | ...... |||||.... . .||||.||..|..|||.|||.. . || |.| aefqrlkeikee-ekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdkt--rafiatqapleetvedFWrmvwqekigviVmLt AEEEGGRTKSHRYWPKlgskhSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVrrhtnsmleg .|| .| |.|||. |...||...|. . . . | .. |.... . .||.| ....||||.| |. . |......|. nliegekkkchqYwPd-----stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks---------- TKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL .. . |.||||||||||||. . . |. . ... |.. ... .||.| |.|| || |....... | slagarpvvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal |
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| Phosphatase | PTPN14.AA | Subfamily.N5_RR.PD | 926-1181 | 33 | 2e-59 | 192.4 | In-house | 16-264 (265) | Show / Hide |
Range on Protein: 926-1181 Range on HMM: 16-264/265 Sequence Identity: 33% (86 aa) STAALPENAERSRIREVVPYEENRVELIPTK--ENNTGYINASHIKVVvGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYW .. .... | ....| |. || | . . .... |||| .|| .. . |.|||||||.| .|||.|.... |.|| |.| .| |.| ..|.|. eelevfgsqtknryktilPnensrvllesessededssyinanyikGy-deeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyf PKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSgQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEgtknrhpPIVVHCSA . . | .||....... .. | . | .|.| . ||.| | ||||||| |.|.. .|. ..|... |...| | |.|||||||.|| Pdaedyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenakla-------Pvvvhcsa GVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL ||. | .. . |.....|.| . || .| |.|| ||......|...| GiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl |
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| Phosphatase | PTPN14.AA | Subfamily.RA.PD | 912-1181 | 33 | 8.8e-59 | 190.3 | In-house | 5-265 (266) | Show / Hide |
Range on Protein: 912-1181 Range on HMM: 5-265/266 Sequence Identity: 33% (91 aa) EYEQIPKKKAN-GIFSTAALPENAERSRIREVVPYEENRVELIPTK-ENNTGYINASHIKVVVggAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVT |...... | . . . ||...|| ...|. ...||. .|| | . |... |||||.|. ..||.|||. .| .|||.|.|||| |.| .| efkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyr--ekdkfiaaqGpkeetvedfwrmiweqksativmlt AEEEGGRTKSHRYWPKLGskhsSATYGKFKVTTKFRTDSVCYATTGLKVKHLL----SGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNS ...| ..|||. | . |||. .|. | | .. |. . |..| ..| | . .| ||. | | . .||..|........ . . elkerkeekcaqywpdeG----lvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsan mlegtknrHpPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL | |||||||||||||| .| . .. .. ..|..| ... || || |.|| ||.|.|.|| ... --------h-pivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlleyi |
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| Phosphatase | PTPN14.AA | Subfamily.RG.PD | 912-1180 | 33 | 8.1e-58 | 187.2 | In-house | 5-262 (264) | Show / Hide |
Range on Protein: 912-1180 Range on HMM: 5-262/264 Sequence Identity: 33% (91 aa) EYEQIPKKKANGI-FSTAALPENAERSRIREVVPYEENRVELIPTKE-NNTGYINASHIKVVVGgaEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVT ..|.| | |.. | ... .|| |. | ..|..|. ||.| |. . ... |||||.|. . .||.|||||..|..|||.|.||....| |.| qfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrr--skeyivtqgplketiedFWrmiWehnaqiivmlt AEEEGGRTKSHRYWPKlgsKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERT--VWHLQYTDWPDHGCPEDVQGFLSYLEEIqsvrrhtnsmL .| || . ..|||| |. . .....||| . .. .| .. . .|. .|.. | ...||.|||.| || .|.. . dldekgrrdedvyWPk---kdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkke----------e EGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQF .|.. |||||.||||||.|..| . .. ||..|.|.| .|.|.| .| ....|. ||.|.|..|... aankeeaGPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel |
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| Phosphatase | PTPN14.AA | Subfamily.N23.PD | 946-1179 | 32 | 2.6e-56 | 182.5 | In-house | 115-347 (350) | Show / Hide |
Range on Protein: 946-1179 Range on HMM: 115-347/350 Sequence Identity: 32% (77 aa) EENRVELI--PTKENNTGYINASHIKVVVGGAEwHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKlgSKHSSATYGKFKVTTK ..|||.| . .... ||||...| .. .. ..||||||.. | |||.||||| ..|| |.| |.||...| ..|||. . . ..|...|. | dpnrvklqqstqpgqqddyinatylkeltpmsP-pfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPi--degetnlfgdlrvslk FRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRrHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYC-LE ..| . |...| . |.| ||..| |...| |. . .| .|.|.... .. | . ||..||||||||||.. . | . slrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetay-aqqrktetegeggkPiilhCsaGvgRtgtfcvvysairelta HNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQ .| ...| ..| ||.|| .|.|. ...|..|.. .. gngiiniprvvrrlrqqRkymvqkkvilkklyeavle |
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| Phosphatase | PTPN14.AA | Subfamily.R_Ecdysozoa.PD | 911-1180 | 29 | 3.4e-56 | 181.7 | In-house | 4-267 (269) | Show / Hide |
Range on Protein: 911-1180 Range on HMM: 4-267/269 Sequence Identity: 29% (81 aa) TEYEQIPKK-KANGIFSTAALPENAERSRIREVVPYEENRVELIPTK-ENNTGYINASHIKVVVggAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMV .|||..... . . .... ||| . | .........|| | ... .... |||||.|| . ..|| |.|. | .|||.|..|| |..| |. eeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgyk--ekkkfiaaqdPveatigDfWrmiaeqevtlivml TAEEEGGRTkSHRYWPKLgskhSSATYGKFKVTTKFRTDSVCYATTGLKVKHLL---SGQERTVWHLQYTDWP-DHGCPEDVQGFLSYLEEIQSVRRHTN . ..| | ..|||. ||. |.. |. |.| . ..| |.|| |. | || .| | ..|..... .. . . snlteknrk-cakyWpie----devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnk SMleGTknrHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQF |. . ||||||||||||.|... .|.. |. ..||.. .. ||.|| ...| ..||.|.|. |... ls--gs---rsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralady |
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| Phosphatase | PTPN14.AA | Subfamily.RC.PD | 911-1180 | 29 | 1.5e-53 | 173.2 | In-house | 4-286 (288) | Show / Hide |
Range on Protein: 911-1180 Range on HMM: 4-286/288 Sequence Identity: 29% (86 aa) TEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVEL--------------------IPTKENNTGYINASHIKVVVGGAewHYIATQGPLPHTC .|....|. .. | .|| .. | .|.||. ||||| |. . |||||.|. |||.|||| | aefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpe--kyiaaqGplketv HDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWpklgsKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFL |||.|..|. |.|| |.| .|| | | .|| . .|| .| | . | | |.... . |.| ..|||.|.... ||. . .| ddfwrmiferkvkvivmltelkeGdrekcaeyw-----eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkell SYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQF . .. .. . .| . |..|||..|..|||. | . .. || .|||.| ... || .| |....||...|.||... kliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet |
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| Phosphatase | PTPN14.AA | Subfamily.RK.PD | 922-1181 | 29 | 1.7e-52 | 169.6 | In-house | 18-266 (267) | Show / Hide |
Range on Protein: 922-1181 Range on HMM: 18-266/267 Sequence Identity: 29% (75 aa) NGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVggAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAE-EEGGRTKSH ...| ...| |..|. ....|. .| ||....... ||||. | ..|.|||||..| .|||..|.... | |.|| || | .|||. sedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsyk--rpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkCl RYWPKlgskHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQ--ERTVWHLQYTDWPDH-GCPEDVQGFLSYLEEIQSVRRHtnsmlegtkNRHPPI ... .||..||. . . . ..|..| || |.| ..|.. ||.. . |. ...|... ....... ... .|||||.|| kyWPe----dtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee---------eeeGri VVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL ||.|. | . .. .|... |.| . . ||.... |..| ||||||.| ...| vvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal |
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| Phosphatase | PTPN14.AA | Subfamily.N20.PD | 912-1181 | 38 | 3.5e-52 | 168.9 | In-house | 5-256 (257) | Show / Hide |
Range on Protein: 912-1181 Range on HMM: 5-256/257 Sequence Identity: 38% (101 aa) EYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKEnntgYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAE |. . |. | | . | | |. | |...||. || | .|. |||||.|..| | |. |||||||| | |||||| |.|||||.| | | efmalelknlpgefnsgnqpsnreknryrdilpydstrvplgkskd----yinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitre EEGGRTKSHRYWPKlgSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYleeiqsVRRHTNSMLEGtk || | ..||| | . .|.| . . ..| .| ..| .||.| ||||| | . |. |.| .| | | |.|| ieggiikcyhywpi--slkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfiky------iryarkshltg-- nrhpPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL |||||.|||||.. .... .. .| ... .. .|||| |.|| ||.|.|..... | ----pmvvhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl |
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| Phosphatase | PTPN14.AA | Subfamily.N1.PD | 925-1179 | 33 | 2.1e-48 | 156.4 | In-house | 20-265 (268) | Show / Hide |
Range on Protein: 925-1179 Range on HMM: 20-265/268 Sequence Identity: 33% (85 aa) FSTAALPENAERSRIREVVPYEENRVELiptKENNTGYINASHIKVvvGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWP ..| |||| .. | |.| ||. |..| ..... ||||| ... |. .|| ||||||||. |||||||| . |. | ...| . |||. treaklpenrglnryrdvspydhsrikl---eradvdyinaslvel--eeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywp KLGSKHsSATYGK--FKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIqsvRRhTNSMlegtKNRHPPIVVHCS ... . .. . .||. . .. . . |... | . . |.. | .|| ||| | || . ||..| .. |. . |... . |.|.|||||.|| qeeeea-ellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkv---re-sgsL----ssdvgpavihCs AGVGRTGVLILSELMIYCLEHNEK---VEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQ .| | | . .. .|.... |.. | ||..|. .||| | .| |. ... agigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile |
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| Phosphatase | PTPN14.AA | Subfamily.RN.PD | 913-1178 | 35 | 2.2e-47 | 152.8 | In-house | 6-260 (264) | Show / Hide |
Range on Protein: 913-1178 Range on HMM: 6-260/264 Sequence Identity: 35% (93 aa) YEQIPKKKANGIFS-TAALPENAERSRIREVVPYEENRVELIP-TKENNTGYINASHIKVVvGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTA .| . . .|. . .| ..|... | ..|.||...||.| ...... ||||| | . ||||||||..| ||||||||||||| ..| wealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildh-dprapayiatqgplsstiadfwqmvweqGvvvivnltr EEEGGRTKSHRYWPKLGSKHSsATYGKFKVTTKFRTDSvcYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYleeiqsvRRHTNSMLEGt || | .. .||||. ||. | |. . .| | . .| | . . ||| . . ||..|.| . .| .|| | | | ||| leeegvkqckrywpdeGsevy-hiyevhlvsehiwcdd--ylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllef-------rrkvnksyrG- knRHPPIVVHCSAGVGRTGVLILSELMIYCLEHN-EKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLI ||||.|.||||| || .|.. | . .... | ||.|| ...| .|..|...... --rscpivvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltava |
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| Phosphatase | PTPN14.AA | Subfamily.N_Nematode_1.PD | 913-1181 | 29 | 9e-46 | 147.6 | In-house | 6-264 (265) | Show / Hide |
Range on Protein: 913-1181 Range on HMM: 6-264/265 Sequence Identity: 29% (81 aa) YEQIPKKKANGifSTAALPENA--ERSRIREVVPYEENRVELIpTKENNTGYINASHIKVVVGGaeWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTA .... | . . .. |. |. .. | ..| ..||| | .. . || | .. . . ..| .|.|| .|..||| || . |. | |. fralkkfndee--kvkafkeaqeadknrykdvgcldknrvkla-eeplpsdyihanyvgtptnp--krficaqaPldktiadfwymvlqekveaivmlck EEEGGRTKSHRYWPKLGSKHSSATYGKFKVTT-------KFRTDSVCYATTGLKVKHllSG-QERTVWHLQYTDWPDHGCPEDVQGFLsyleeiqsvrrh | |..| . |.| .. . . .. |.| | .|. . .| |.|.. .| ..|.| |.|.|||||.| |. . | liekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvleveg--aGektrkvthyqWtdWPdrGvPpadlaal------------ tnSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKV-EVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL .|| ... . |||||||||.|||| .. |... | ........ ... .|||| . ||| ||| ||..||.... --elleavrgskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllnyf |
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| Phosphatase | PTPN14.AA | Subfamily.N_Nematode_6.PD | 912-1181 | 27 | 5e-42 | 135.4 | In-house | 5-252 (253) | Show / Hide |
Range on Protein: 912-1181 Range on HMM: 5-252/253 Sequence Identity: 27% (76 aa) EYEQIPKKKANGifSTAALPENAERSRIREVVPYEENRVELiptKENNTGYINASHIKVVVggAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAE ||.. |.. .. .. |. .. .| | ... .. |..| .... || |. .|. . .| ||.|| |...||.|. .||. | |. eykdspneases--eataflkfkdrnrytniqCcdagrlkl---addedfyihanlvkist--kprrlictqaplegtieefwkmilssgveyivmlcel EEGGRTKSHRYWP-KLGskhSSATYGKFKVTTKFRTDSVCYAT-TGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSyleeiqsvrrhtnsMLEG | |. || .| . |.| . ..|. .| ... . ||. ...| | |... .||||| |.... | .|. vekgkeksaeylsdkvG---darkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalr--------------llsv TKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL |. . |||||||||||||| |.| . .. .| . .. .|. .| .|||.|. .||. || .... ....| vkkdkkPivvhCsaGvGrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvleyl |
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| Phosphatase | PTPN14.AA | Subfamily.R_Nematode_2.PD | 933-1180 | 32 | 2.5e-41 | 133.0 | In-house | 29-259 (261) | Show / Hide |
Range on Protein: 933-1180 Range on HMM: 29-259/261 Sequence Identity: 32% (74 aa) NAERSRIREVVPYEENRVELIPTKENNTgyINASHIKVvvGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLgsKHSS .... | .| .| .|| | . | | .. | . ..||||||| |..||| || . |. | |.. |..| ..|.| .... . pkdkhRypdvPCkpetavevivdgkrvp--ihanwvpt--agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfple--tsqk ATYGKFKVTTKFRTDSVC--YATTGLKVKHLLS-GQERTVWHLQYTDWPDHGCPEDVqgflsyleeiqsvrRHTNSMLEGTKNRHPPIVVHCSAGVGRTG |.|...|. . . . |||. . ||| |.||..|||.| |... .|| .|. . |||||||||.|||. .| .| . .|.....| ldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPksh--------------aelfeLlelvkksekPivvhCsaGiGRtm VLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQF . .|. |||.|. ||| |. ..... afigteylareveadptieltealkelrehRwkgiqtesqlywltlgalyr |
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| Phosphatase | PTPN14.AA | PTPc_motif | 1068-1179 | 32 | 1.2e-40 | 142.33 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 1068-1179 Range on HMM: 1-92/92 Sequence Identity: 32% (38 aa) TVWHLQYTDWPDH-----GCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMF ||.|..||.|||| |.|| ...|........ |||||||||.||||.... ..|. . | . .... .|.||.. TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-----------------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPG MIQTIAQYKFVYQVLIQ |.|| .||.|.|..... MVQTEEQYIFCYRCILE |
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| Phosphatase | PTPN14.AA | Subfamily.N_Fungi_PTP1.PD | 934-1180 | 24 | 1.7e-39 | 127.1 | In-house | 46-341 (343) | Show / Hide |
Range on Protein: 934-1180 Range on HMM: 46-341/343 Sequence Identity: 24% (71 aa) AERSRIREVVPYEENRVELI----PTK-----ENNTGYINASHIKVVVGG----AEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSH . | ....||| .||.| ... . ||||...|. . . ....|||||.||| | .||.... . .|.|| ..|.. | .. | .|| faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy RYWPKLGSKH-----------SSATYG----KFKVTTKFR----TDSVCYATTGLKV--KHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSV |.... . . . ..| ... . .. .. . ... .|..||. |.| . . . .|. || . . rYWqegsydditvklaskwenimgindsslysadvkkeasdndnksddndlnnnndltpvtaavsepyevyqlqvknWkDlslllnPesilqalevkndl RRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLI-----LSE--LMIYCLEHNEKVEVPMMLR--------LLREQRMFMIQTIAQYKFVYQVLIQF .. . ..| .||.|||||||||||.|. ||. ... .|..|. ..| ||.||. |.|.. |. |.|. | . iddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfy |
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| Phosphatase | PTPN14.AA | Subfamily.N_Nematode_4.PD | 922-1180 | 28 | 1.3e-37 | 120.9 | In-house | 15-262 (264) | Show / Hide |
Range on Protein: 922-1180 Range on HMM: 15-262/264 Sequence Identity: 28% (75 aa) NGIFSTAALPENAERSRIREVVPYEENRVELIpTKENNTGYINASHIKVVvggAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHR . . | .|....| .... .|.|| | .. . || || ... . .||.|||||..| .||| ||... ..|. |. .|.| | | ppnvtasaseknsdknryadilcidetrvvlk-nrdpdndyihaswmrmP---dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcar YWPKlgSKHSSATYGKFKVTTKFRTDSVcYAT---TGLKVKHLL-----SGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQsvrrhtnsmlEgtKNR |.|. .. . ..||...| .. | .| ||| . .. | |.|.. |.|. |.| . . . .. . |.. yype--ksekvvkfGkyritlvekkeev-iadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavk----------k--kkk HPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQF . ||||||||||||| |. .. . | ..|| ..| ||.|. .|. |. |.. |||.. ekPivvhcsaGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvliel |
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| Phosphatase | PTPN14.AA | Subfamily.N_Nematode_5.PD | 911-1181 | 24 | 1.6e-37 | 120.4 | In-house | 4-257 (258) | Show / Hide |
Range on Protein: 911-1181 Range on HMM: 4-257/258 Sequence Identity: 24% (67 aa) TEYEQIPKKKANGIfSTAALPENAERSRIREVVPYEENRVelIPTKENnTGYINASHIKVVVggAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTA ||.|.. . |.| .. | .| ...| .| ..|.|| ..|.|. .|||||.||. .| ..| || |||.| .|||.|| .. .. . ... tefeklaslkpnke-tckafeknlkknrskdvkilDetrV--kltded-dsYinaskikldd--lekkliltQlPlpdteedFWrmvyqekitsvvllve EEEGGRTKShRYWPKLGSKHssATYGKFKVTTK-FRTDSVCYatTGLKVKHLLSG--QERTVWHLQYTDWPDHGCPEDVQGFLSyleeiqsvrRHTNSML .|| .|. ..|. . ..||. .... . ... .. . ..|. | | .. . ...| |... |..|. . | ...|. deelketav-sffpletgdy--lnlgkmfinnrkvevkedek--keytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik---------raiekvl EGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL .. ...|.||....|.||.| ..| ...| .|........ .|. .|.||. ......|| .||....... skkqgknapvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldyi |
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| Phosphatase | PTPN14.AA | Subfamily.R_Nematode_3.PD | 926-1181 | 22 | 1.1e-30 | 98.2 | In-house | 21-266 (267) | Show / Hide |
Range on Protein: 926-1181 Range on HMM: 21-266/267 Sequence Identity: 22% (62 aa) StaalpENAERSRIREVVPYEENRVELIP-TKENNTGYINASHIKVVvGGAEWhyIATQGPL--------PHTCHDFWQMVWEQGVNVIAMVTAEEE--- | .. . | || .|..|| | | . ..|.|. ... .|... | ||.|. |. ||.|....|....|. | . s-----kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecp-nglkl--IltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedg GGRTKSHRYWPKlgSKHSSATYGKFKVTT-KFRTDSV-CYATTGLKVkHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRrhTnsmlegtk . |. .|.|. .. . . ....|.. . .. . |.| .. ..| || ||.|..|.... ||. . .|. .. ..... | eeeekcseYype--kvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk--t-------- nrhpPIVVHCSAGVGRTGVLILSELMIYCLEHNE-KVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL |.|||||.|..|...| || . . ... |... .. ||.|| ||| .. || .....| ----pvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkll |
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| Phosphatase | PTPN14.AA | Subfamily.N_Nematode_eak.PD | 927-1181 | 24 | 7.1e-27 | 85.7 | In-house | 20-280 (281) | Show / Hide |
Range on Protein: 927-1181
Range on HMM: 20-280/281
Sequence Identity: 24% (65 aa)
TAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGaeWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKL
.| |. .| |. ..||.. . |.| ... |. |||||| .. | .|| | . . ||||| || |.. . | . || .|.|. .
vtarleavnrnrvvkivpqdrylvrltssqlnrdGyinaslaefsevG--rkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdk
GskhSSATYGKFKVTTK-FRTDSVCYATTGLKVKHllsGQE-RTVWHLQYTDWPDHGCPEdVQGFLSYLEEIQSV-----RRHTNSMLEGTKNR--H-PP
||...|..| . . | |... |.| | | .. | . |.. ||.. . .. | ...|. | .. | ||
t---evlkyGildverkeyavkrniletrllilrk---GnethrvlhykvfGwtettlpk-yedflalrkvmkevGvlllivmksallrstlkkyihtpp
I---VVHCSAGVGRTGVLILSELMIYCLEHNEKV--EVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL
.. .. | |.||... .|.| .. . | |.. ...|. . . |. |.|......|
sfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl
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| Phosphatase | PTPN14.AA | Subfamily.N_Nematode_egg.PD | 913-1181 | 26 | 1.2e-24 | 78.4 | In-house | 6-256 (257) | Show / Hide |
Range on Protein: 913-1181 Range on HMM: 6-256/257 Sequence Identity: 26% (69 aa) YEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELI-PTKENNTGYINASHIKvvvGGAE-WHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTA .|.. . . ..||| .. |..| . | | ||.| . .| | ..| |. ..| .| || |.|||.||... |. | |.|. feilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvk---Gkpllnefilaqaplkntvedfwrmvfqekvqyivmlts EEEGgrTKSHRYWPKLGSKHSSATYGKFKVTTkFRTDSVC---YATTGLKVkhllSGQErtvwhlqytdwPDHGCPEDVQGFLSYLEEIQSVRRhtnsML | . . |||| |. | ..... .. || . | ||. | .. | || . || .. | | .| .| |.||. akes--erceyywpkaeseslvtvpGslrien-lkvdskadplfrvtklkl----vGgd-----------deelflehwqgdvnylsdvysplr----vl EGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEH--NEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFL . || ....|. |. . || | .|| .| . .... .| |||.....|. rklrnlskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlffi |
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| Phosphatase | PTPN14.AA | Family.DSP.PD | 996-1177 | 16 | 2.5e-11 | 34.8 | In-house | 128-241 (387) | Show / Hide |
Range on Protein: 996-1177 Range on HMM: 128-241/387 Sequence Identity: 16% (30 aa) MvWEQGVNVIAMVTaeeeggrtkshrywpklgskhssatY------GkfkvttkfrtdsvcyattglkvkhllsgqERTVWHLQYtDWPDHGCPEDVQGF . | ||..| .| . | . .|.. ..||..|. | . l-kelgvtkivnlt-------------------------ddkpqftk-----------------------------elgikylri-pidDhnapplenlf LSYLEEIQSvrrhtnsmlegTKNRHPPIVVHCSAGVGRTGVLILSELMIYclehnEKVEVPMMLRLLREQRmfMIQTIAQYKFVYQVL .. |.. .. . ..||| ||.||.|.|| || . |... . |...|..| ... ...|. |. ekaidfiee-----------gndskgvVlVHCkaGkgRsgtliiaYlmks-----egltleealdwvrskR--pgvitpnqgflkqlk |
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| Phosphatase | PTPN14.AA | Subfamily.PTPDC1.PD | 1116-1175 | 37 | 1.1e-08 | 26.2 | In-house | 168-222 (229) | Show / Hide |
Range on Protein: 1116-1175 Range on HMM: 168-222/229 Sequence Identity: 37% (22 aa) PIVVHCSAGVGRTGVLILSeLMIYCLEhnekVEVPMMLRLLREQRMFMIQTIAQYKFVYQ | ||| || ||||||| . ..| . .. ..|.|..| ||| | ..| . kiavHCHAGlGRtGvliac-ylvyakr----ltaeeaiklvrskrpksiqtreqvelvee |
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| Phosphatase | PTPN14.AA | Subfamily.CDC14.PD | 1107-1147 | 42 | 1.1e-06 | 19.8 | In-house | 191-232 (258) | Show / Hide |
Range on Protein: 1107-1147 Range on HMM: 191-232/258 Sequence Identity: 42% (18 aa) LEGTKNRHPPIVVHCSAGVGRTGVLILSELMI-YCLEHNEKV || | . . |.||| ||.||||.|| . |.. | ....| . leitekaeGaiavhCkaGLGrtgtligcylikhyrftaaeti |
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| Phosphatase | PTPN14.AA | Subfamily.PTEN.PD | 1116-1144 | 42 | 1.2e-06 | 19.4 | In-house | 96-124 (305) | Show / Hide |
Range on Protein: 1116-1144 Range on HMM: 96-124/305 Sequence Identity: 42% (12 aa) PIVVHCSAGVGRTGVLILSELMIYCLEHN ..||| || |||||.| . |. .. .. VvavHCkaGkGRtGvmicayLlksgikks |
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