Gene PTPN20B
PTPN20B
Species: Human
Alias: PTPN20B, DKFZp781P23155, bA42B19.1, DKFZp566K0524
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTPN20B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PTPN20B.AA | Subfamily.N6.PD | 153-411 | 36 | 1.3e-67 | 219.5 | In-house | 8-292 (295) | Show / Hide |
Range on Protein: 153-411 Range on HMM: 8-292/295 Sequence Identity: 36% (103 aa) KTAAYDIMQEFMALELKNLPGEF--NSGNQPSNREKNRYRDILPYDSTRVPLGKS------KDYINASYIR--------IVNCGEE---YFYIATQGPLL |. . ...|| |. .. . ..|....|.|||||..|||.| ||| | .|||||.||| | . | ||||||.| ksqtlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLk STIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLeLKHFRVFLENYQILQYFIIRMFQVVEK-STGTSHSVKQLQFTKWPDHGTPASADS .|. |||.|| ..||.|| |.|.|.| | ||..||| . .| . .| . . . ...| |.| .| . ..... |..|..|||||.|... dtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkke-tGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgv FIKYIRYA--RKSHL--TGPMVVHCSAGIGRTGVFLCVDVVFCAIVKN---CSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLE ...... ....| .||.|||||||||||| |. .|.| | .. . .| .. ..|.||||.|||..||.| |.| vlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqf |
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| Phosphatase | PTPN20B.AA | Subfamily.N20.PD | 158-414 | 100 | 2.6e-191 | 624.8 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 158-414 Range on HMM: 1-257/257 Sequence Identity: 100% (257 aa) DIMQEFMALELKNLPGEFNSGNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITRE |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| dimqefmalelknlpgefnsgnqpsnreknryrdilpydstrvplgkskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitre IEGGIIKCYHYWPISLKKPLELKHFRVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAGI |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| ieggiikcyhywpislkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshltgpmvvhcsagi GRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLR ||||||||||||||||||||||||||||||||||||||||||||||||||||||||| grtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevlr |
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| Phosphatase | PTPN20B.AA | PTPc | 158-414 | 33 | 6.1e-118 | 399.03 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 158-414 Range on HMM: 1-308/308 Sequence Identity: 33% (106 aa) DIMQEFMALELKNLPG---------EFNSGNQPSNR--EKNRYR-DILPYDSTRVPLGKSK---------DYINASYIRIVNCGEEYFYIATQGPLLSTI . .||. |. . . ...... | || .||||. ||..||.||| | . . |||||.||.. ... ||.||||| .|| GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY--WRPKRYICTQGPLPHTI DDFWQMVLENNSNVIAMITREIEG--------GIIKCYHYWPISLKKPLELKHFRVFLENYQILQ-YFIIRMFQVVEKST--------GTSHSVKQLQFT .|||.|| .... .|.|.....|. | .|| .||| |.. .|..| ........ ....| |.| . . . ...|.....| EDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYT KWPDHGTPASADSFIKYIRYARKSHL---------------------TGPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQT |||||.| |.|||...||. |... |||.|||||||.||||.|...|.. . | . ..| .|| .||.|| ||||| NWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQT KEQYHFCYDIVLEVLR .|||.|||...||... EEQYIFCYRCILEYIK |
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| Phosphatase | PTPN20B.AA | Y_phosphatase | 183-411 | 40 | 1.6e-111 | 381.56 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 183-411 Range on HMM: 1-243/243 Sequence Identity: 40% (98 aa) NREKNRYRDILPYDSTRVPLG-----KSKDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGI-IK-CYHYWPI-SLK |.|||||.||..||.||| |. .. |||||.||.. . ... ||.||||. .||.|||.||..... .|.|.....|.| .| |..||| NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDG-PYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEG KPLELKHFRVFLENYQILQYFIIRMFQVVEKST--GTSHSVKQLQFTKWPDHGTPAS-ADSFIKYIRYARKSHL---TG--PMVVHCSAGIGRTGVFLCV |.. .|.| ..... ......|.|.| . . ...|.....| |||||.| | ..|....||. ||.. | |.|||||||.||||.| .. QPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAI DVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLE |.. . . .. ...|..|| .||.|| ||||| ||| |||...|| DIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | PTPN20B.AA | Subfamily.N13.PD | 174-413 | 47 | 4.4e-93 | 302.9 | In-house | 17-258 (259) | Show / Hide |
Range on Protein: 174-413 Range on HMM: 17-258/259 Sequence Identity: 47% (114 aa) EFNSGNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISL . ..|.. .|..|||||..|||| |||.||.. |||||.|.. .|| |||.|||| |..|||||| | ...||||.| | |.| .||||| . .| tcevgkkkenkdknryrnvlPydetrvklgdeggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerk KKPLELKH-FRVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHL-TGPMVVHCSAGIGRTGVFLCVDVVFC .| .. ..| |...| |. | .| ..| .. .| |. | .|.|.||||||.|.||......... |. . .||.||||||||||.||....|||. | nkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqtdagPivvhcsaGiGrsGvlitidvvlg AIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL .. .|.. .|| ..|||| |.||||.|| |.| ..|||| lierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl |
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| Phosphatase | PTPN20B.AA | Subfamily.N3.PD | 174-412 | 41 | 2.4e-78 | 254.4 | In-house | 17-259 (261) | Show / Hide |
Range on Protein: 174-412 Range on HMM: 17-259/261 Sequence Identity: 41% (100 aa) EFNSGNQPSNREKNRYRDILPYDSTRVPLGKSK-DYINASYIRIVNCGEEYF--YIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWP . ..| | .|||||||||||.||| | .|. |||||.|. . ... |||||||| .| |||||| |..|..| |.| .| | .||..||| aisaarkpenlaknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqyWP IsLKKPLELKHFRVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSH--LTGPMVVHCSAGIGRTGVFLCVDV .. ||. .|.| .|. . . ...| . . .|.| .... |||.. ||||| | ....|..... || . . |.|||||||||||||.. ... . e-tedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlillet VFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV . | .. .....||| .||.||. .|||..||.| . .|.. alalieaaepvypldivrtmrdqramlvqtvsqykfvCeailka |
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| Phosphatase | PTPN20B.AA | Subfamily.R_Anemone_2.PD | 160-413 | 41 | 2.4e-75 | 244.9 | In-house | 3-261 (262) | Show / Hide |
Range on Protein: 160-413 Range on HMM: 3-261/262 Sequence Identity: 41% (108 aa) MQEFMAL-ELKNLPGEFNSGNQPSNREKNRYRDILPYDSTRVPLGK-----SKDYINASYIRIVNcgEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAM .|. .| .. . ...| ..| |. |||| .||.||.||| | . . |||||.|| . .. |||||.|| ||.|||.|| | || || |. seeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyr--rkkayiatqaPlpetiedfWrmvWeqnsavivm ITREIEGGIIKCYHYWPIslKKPLELKHFRVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSH---LTGPMV |.| | | .|. .||| |.. .... .| |.. |.....| |.| .. . . |.| ..|.|||.|.|.|. |... .| ..| . .||.|| ltqeeergkakvhryWPs--kgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpiv VHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL |||||.||||||. ||... | .. .....| |.||||. |||||.||.|.||..|| | vhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal |
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| Phosphatase | PTPN20B.AA | Subfamily.RB.PD | 174-413 | 39 | 7.4e-74 | 239.8 | In-house | 17-260 (261) | Show / Hide |
Range on Protein: 174-413 Range on HMM: 17-260/261 Sequence Identity: 39% (98 aa) EFNSGNQPSNREKNRYRDILPYDSTRVPL-----GKSKDYINASYIRIVNCGEEyfYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHY . .. ... ||.|||.. |||||..|| | ...|||||.|| |. | |||||||| .|.||||.||.|..|..| |.|. .|.|.|| .|| avkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspre--yiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeY WPISlKKPLELKHFRVFLENYQILQYFIIRMFQVVEKSTgtSHSVKQLQFTKWPDHGTPASADSFIKYIRYARK----SHLTGPMVVHCSAGIGRTGVFL | . ..| . .| | . . |. ..|| |.. .... ...|.|..|| |||||.| .... ....| |. . ..|.|||||||.||||.|. WPad-eepvlyGdikvtllaekeldewvirefkiekgke--krkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfi CVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL .| .. || .| ... .||..||.| .|||..|| | ....|..| aldrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldll |
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| Phosphatase | PTPN20B.AA | Subfamily.N12.PD | 176-413 | 40 | 2e-73 | 238.2 | In-house | 25-269 (270) | Show / Hide |
Range on Protein: 176-413 Range on HMM: 25-269/270 Sequence Identity: 40% (102 aa) NSGNQPSNREKNRYRDILPYDSTRVPLGKS-----KDYINASYIRIVNcgEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWP ..|....|..||||.|||||| .|| | | .|||||..|. |. .. |||.|||| .|.||||.|. | | ... |. ||.| | .|| .||| eagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgve--gkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWp ISLKKPLELKHFRVFLENYQILQ-YFIIRMFQVVEKstGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHL--TGPMVVHCSAGIGRTGVFLCVD . ...|| .|.| ||. . .. |.||...| . ..|..|.|...|.|||||.|.||.| .. |. .|. . |.|||||||.||||. . .| eegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaid VVFCAIVKNCS---FNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL | .. .. ... |.|...|.||. .|||||||.. | |.|.. yvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv |
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| Phosphatase | PTPN20B.AA | Subfamily.N_Choan_1.PD | 170-413 | 37 | 2.5e-70 | 228.3 | In-house | 13-261 (262) | Show / Hide |
Range on Protein: 170-413 Range on HMM: 13-261/262 Sequence Identity: 37% (92 aa) NLPGEFNSGNQPSNREKNRYRDILPYDSTRVPL-----GKSKDYINASYIRIVNCGEEyfYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIK .. .. ....|..||||..| || ||| . |. |||||... .. .| |||||||. .....|||||.|.. ..|.|.|||||.| .| gvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgeke--yiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklk CYHYWPiSLKKPLELKHFRVFLENYQILQYFIIRMFQVvEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYA---RKSHLTGPMVVHCSAGIGRTG |..||| .. |.| ...| .. . . .| | |.. |...| . .|.||..|.||||| ||.. .... ..|.. |.|.|||||.||||... . ChryWP-denselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtG VFLCVDVVFCAIVKNCSF-NIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL | .. |. .. . .. ..||..|..| |||| ||.| | .||..| tyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal |
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| Phosphatase | PTPN20B.AA | Subfamily.R_Sponge_2.PD | 174-412 | 34 | 3e-69 | 224.8 | In-house | 16-260 (262) | Show / Hide |
Range on Protein: 174-412 Range on HMM: 16-260/262 Sequence Identity: 34% (83 aa) EFNSGNQPSNREKNRYRDILPYDSTRVPLGK----SKDYINASYIRIVNCGEeyFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYW ... .....| |||...|||||..|| | . ||||||.. . . |||||||| .|..||| ||.| ... | |.|| | || .||| slsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrrk--ayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYW PISLKKPLELKHFRVFLENYQILQYFIIRMFQVVEKST-GTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHL---TGPMVVHCSAGIGRTGVFLC .. |. .|.| |.. . |. .||| ... .... . .. |.| .|..||.|..|..| |... |..... ....|.||.|.|||| |...|.|. PekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfia VDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV . .. . .. ......| .| |.||...||.|..|..||. ldsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalley |
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| Phosphatase | PTPN20B.AA | Subfamily.R_Anemone_1.PD | 172-413 | 40 | 2.4e-68 | 222.0 | In-house | 14-257 (258) | Show / Hide |
Range on Protein: 172-413 Range on HMM: 14-257/258 Sequence Identity: 40% (100 aa) PGEFNSGNQPSNREKNRYRDILPYDSTRVPLGK-----SKDYINASYIRIVNcgEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCY | .......|..|||| ||...|..|| | | . |||||||.| . . .||||.|| .|..|||.||..... |||.| ||| || .|| eeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasd--ktrafiatqapleetvedFWrmvwqekigviVmLtnliegekkkch HYWPIslkKPLELKHFRVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLT--GPMVVHCSAGIGRTGVFL | .. . ..|| |.. . .||| . . .|.. ... | |..||.|||.| | | . ...| .||.|. |.|||||||.||||.|| .| qYwPd---stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaGvgRtGafl CVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL .. . |. .|...| ..||.| |||||||| |.. .||| | vidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal |
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| Phosphatase | PTPN20B.AA | Subfamily.N14.PD | 159-413 | 34 | 9.3e-66 | 213.2 | In-house | 2-274 (275) | Show / Hide |
Range on Protein: 159-413 Range on HMM: 2-274/275 Sequence Identity: 34% (92 aa) IMQEFMALELKNLPGEFNSGNQPSNREKNRYRDILPYDSTRVPLGKS----KDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMI . .|. . |.. ....... | | ||||..|.|||. .|| | . ..||||| |... .|.|..||..|||| |. |||||| |....|.|.| vfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivml TREIEGGIIKCYHYWPIS--LKKPLELKHFRVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYI------RYARKSHLT .|.|.| |...|.| . || .| ..|.| . . . .| . ... .. .| ||.| ||||| | ..|....|.. .|. teeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseve ------GPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL |..||||||.||||| . .|.. .. .| . .| ..|..|.|| .||| ||.| |..... | svkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikyl |
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| Phosphatase | PTPN20B.AA | Subfamily.N9.PD | 159-411 | 36 | 1.1e-63 | 206.7 | In-house | 2-272 (275) | Show / Hide |
Range on Protein: 159-411 Range on HMM: 2-272/275 Sequence Identity: 36% (99 aa) IMQEFMALELKNLPGEFNSGNQPSNREKNRYRDILPYDSTRVPLGKS-----KDYINASYIRIVNcgEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAM ...|.... .. |.|. ....| ||||| |.| ||.||| | | |||||... . .. .||||||| |..|||.|| |..|| |.| lskeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGyk--qkkafiatqGplkktvsdfwrmvweqevlvivm ITREIEGGIIKCYHYWPISLKKPLELKHFRVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARK----------- | .| | .|| .||| . .. | ...| . . . . .|.... . |. | .| ||. |||.|.| || |... .. .|. ttrvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgd ---SHLTG-PMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLE ||.| |.|||||||||||| | .|. . . .... | ..|.||. ..||.|||.||| ||| eskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle |
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| Phosphatase | PTPN20B.AA | Subfamily.RG.PD | 174-413 | 37 | 1.6e-63 | 206.0 | In-house | 18-263 (264) | Show / Hide |
Range on Protein: 174-413 Range on HMM: 18-263/264 Sequence Identity: 37% (92 aa) EFNSGNQPSNREKNRYRDILPYDSTRVPL----G-KSKDYINASYIRIVNCGEEyfYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHY | .| ....|.||||. .|......||.| | ..|||||||||. . .| ||.||||| .||.|||.|. |.|...| |.| | |.. ||| eaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrske--yivtqgplketiedFWrmiWehnaqiivmltdldekgrrdedvy WPISlKKPLELKHFRVFLENYQILQYFIIRMFQVVEKSTGTSHS--VKQLQFTKWPDHGTPASADSFIKYIR--YARKSHLTGPMVVHCSAGIGRTGVFL ..||||....| | . . |.....| |.. .. . .... |.|...|||||.|.| |. .. ... | ... .||.|||.||| ||.|... . WPkk-deplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivvhdsaGvgragtyi CVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL | . . |. . |. ... ..| .| |.|.|.||| | ||..||.. aldtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallelv |
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| Phosphatase | PTPN20B.AA | Subfamily.RK.PD | 160-413 | 34 | 2.5e-63 | 205.1 | In-house | 3-266 (267) | Show / Hide |
Range on Protein: 160-413 Range on HMM: 3-266/267 Sequence Identity: 34% (93 aa) MQEFMALE---LKNLPGEFNSGNQPSNREKNRYRDILPYDSTRVPL----GKSKDYINASYIRIVNcgEEYFYIATQGPLLSTIDDFWQMVLENNSNVIA .|| .|. . ..... ...||||||. |||.|| ..| | | | |||||..| . .|.||||| .|. |||..|...|. | | keefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsyk--rpaafivtqgPlqetvkdfWrlvydencasiv MITRE-IEGGIIKCYHYWPISLKKplELKHFRVFLENYQILQYFIIRMFQVVE--KSTGTSHSVKQLQFTKWPDH-GTPASADSFIKYIRYARKSHLT-- .| .| | .||..||| .. . ....| | . .... ...|.|.| . .. . |.|.||..||.. ..| |. |..|.|| ||. mlteldvevgrvkClkyWPedtev--rygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeee -GPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL |..||||.|| ||.|.|. .|.| | .. .. .| ..|.... ||.|.|||.|.||..|| | eGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal |
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| Phosphatase | PTPN20B.AA | Subfamily.RA.PD | 161-412 | 36 | 5.2e-62 | 201.0 | In-house | 4-264 (266) | Show / Hide |
Range on Protein: 161-412 Range on HMM: 4-264/266 Sequence Identity: 36% (94 aa) QEFMALELKNLP-GEFNSGNQPSNREKNRYRDILPYDSTRVPLGK-----SKDYINASYIRIVNcgEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMI .|| .| .. .... .|.. |..|||. .||||| .|| | . . ||||||.| . | .||.|||. |..|||.|. | .|| |.| eefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyr--ekdkfiaaqGpkeetvedfwrmiweqksativml TREIEGGIIKCYHYWPISlkKPLELKHFRVFLENYQILQYFIIRMFQVVEKSTGT----SHSVKQLQFTKWPDHGTPASADSFIKYIRYARKS--HLTG- | . ||. ||| . . || ... ..|. . .| | | ... | | |.|. || ||. | ||.. .|....| .. |.|| telkerkeekcaqywpde--GlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanh PMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV |||||.|||| |. .| |. . . .....| ..| ||. ||||.|||.|.| ..|| pivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlley |
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| Phosphatase | PTPN20B.AA | Subfamily.N5_RR.PD | 170-410 | 31 | 8e-61 | 197.1 | In-house | 8-261 (265) | Show / Hide |
Range on Protein: 170-410 Range on HMM: 8-261/265 Sequence Identity: 31% (81 aa) NLPGEF--NSGNQPSNREKNRYRDILPYDSTRVPLG----K--SKDYINASYIRIVNcGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGG .|| .| . . . . .||||..||| . .|| | . .|||| ||. . .|. |.|||||| .||.|||.|. .....|||.|. | elPlnfsqeelevfgsqtknryktilPnensrvllesessededssyinanyikGyd-eeskayvatqGPlpntiadfWrmiyqeevqvivmltklkean IIKCYHYWPISLKKPLELKHFRVFLENYQILQ--YFIIRMFQVVEKSTgTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKS-----HLTGPMVVHCS || .|.| . . .. .. | ... .|.. . .| . . . ..||| .|.|||| .| ....... .. ..| . ..|.|||||| rqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcs AGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVL ||||||.|..... . .. ... ||...| .| |||||.|||.. . .. aGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc |
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| Phosphatase | PTPN20B.AA | Subfamily.N1.PD | 170-411 | 36 | 1.1e-59 | 193.5 | In-house | 15-265 (268) | Show / Hide |
Range on Protein: 170-411 Range on HMM: 15-265/268 Sequence Identity: 36% (91 aa) NLPGEFNSGNQPSNREKNRYRDILPYDSTRVPLGK-SKDYINASYIRIVNCGEEyfYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHY . | .. ..|.||..|||||. ||| .|. | . ..|||||| . . . . . || ||||| |.| ||||| |.|| . |. . .| .|||..|| ekeletreaklpenrglnryrdvspydhsrikleradvdyinaslveleeakrr--YiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqy WPISLKK-PLELKH--FRVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHL----TGPMVVHCSAGIGRTG | .. |.|.. ..| | .. .||. |.... ...| .. . . ..|.||| | | | .|.|.. |.| . ||.|.||||||||.| wpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsg VFLCVDVVFCAIVKNCS---FNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLE . || .. | |. .| . . ..|..| |..|| .| .| | .|| tlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile |
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| Phosphatase | PTPN20B.AA | Subfamily.N23.PD | 176-413 | 33 | 1.8e-58 | 189.6 | In-house | 102-349 (350) | Show / Hide |
Range on Protein: 176-413 Range on HMM: 102-349/350 Sequence Identity: 33% (83 aa) NSGNQPSNREKNRYRDILPYD-STRvPlGKSKDYINASYIRIVNCGEEYFyIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLK ||.| ..... . .. . ||. | |. |||||.|.. . . | ||||||. ||. |||.|| |. |.|| |.|.| ||. || .|||| . gsGqqqgtpdsrhdpnrvklqqstq-p-gqqddyinatylkeltpmsPpf-iatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPideg KPLELKHFRVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSH-----L-T-----GPMVVHCSAGIGRTGVF . ..|| |.. . ...| |.... . . | ..|..|..|.|...| |.| ....... ... . | |...|||||.||||.| etnlfgdlrvslkslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtf LCVDVVFCAI-VKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL .| . .. ..| ||...| ..|.|| |||.|......|..||| cvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkklyeavleaa |
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| Phosphatase | PTPN20B.AA | Subfamily.N_Choan_2.PD | 181-411 | 31 | 2.2e-58 | 188.9 | In-house | 19-263 (266) | Show / Hide |
Range on Protein: 181-411 Range on HMM: 19-263/266 Sequence Identity: 31% (77 aa) PSNREKNRYRDILPYDSTRVPLGKS-----KDYINASYIRIVNCGEEYfYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKK .|.. |||.|||| ||| | . |||| |.| .. ... |||..||| .|. .||.|..|.... |.|.| | ||| ||| . |. .. arnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkk-YiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepke PLEL--KHFRVFLENYQILQYFIIRMFQVVEksTGTSHSVKQLQFTKWPDHGTPASAD------SFIKYIRYARKSHL----TGPMVVHCSAGIGRTGVF | . .|. .. . . .|.. .. . |...... ....||||| | ..| . .| .| |... ..|..||||||.||||... . kvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtl LCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLE | ..... .. . ... |....|..| .||. |||.. | |.| iaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavve |
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| Phosphatase | PTPN20B.AA | Subfamily.R_Ecdysozoa.PD | 160-411 | 32 | 1.1e-56 | 183.4 | In-house | 3-266 (269) | Show / Hide |
Range on Protein: 160-411 Range on HMM: 3-266/269 Sequence Identity: 32% (86 aa) MQEFMALELK-NLPGEFNSGNQPSNREKNRYRDILPYDSTRVPLGK-----SKDYINASYIRIVNcgEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAM .|. || . . . . . ... | ||||.|| ..|.||| | | . ||||||.|. . |. .|| |.|. .||.|||.|. | ....| |. eeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgyk--ekkkfiaaqdPveatigDfWrmiaeqevtlivm ITREIEGGIIkCYHYWPISlkKPLELKHFRVFLENYQILQYFIIRMFQVVEKS---TGTSHSVKQLQFTKWP-DHGTPASADSFIKYIRYARK----S-- . . | | .|||| . . . | | . . ...||| ..| .| |. | | ..|.|. | | .| . .|.|. .|. . lsnlteknrk-cakyWpie--devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnkl -HLTGPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLE .|.||||||| ||.|.|...|... . .. . .|...| ..|.||. .||||| |.| ... sgsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad |
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| Phosphatase | PTPN20B.AA | Subfamily.N_Nematode_4.PD | 172-412 | 33 | 1.3e-52 | 170.2 | In-house | 15-262 (264) | Show / Hide |
Range on Protein: 172-412 Range on HMM: 15-262/264 Sequence Identity: 33% (82 aa) PGEFNSGNQPSNREKNRYRDILPYDSTRVPLGKS---KDYINASYIRIVncgEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHY | . . | .||||.||| | ||| | . .||| ||..|. ... ||.||||| |..||| || .. .|.|. ||.|. || |. ppnvtasaseknsdknryadilcidetrvvlknrdpdndyihaswmrmP---dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcary WPISLKKPLELKHFRVFLENYQIL--QYFIIRMFQVVEKS---TGTS--HSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAGIGRTG | ..| .. ..|. | . . |.. ..|.. .| || .|...|.|. .|| . || ... .| . .|.|||||||.||| .. ypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkkekPivvhcsaGvGrta VFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV .| | | . ...||| ..|. | . ||.. |. | . ...| tlvGidyatirirenseievldivrelramrlkavqshlqflfllvvliel |
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| Phosphatase | PTPN20B.AA | Subfamily.N_Nematode_1.PD | 160-412 | 32 | 6.7e-51 | 164.5 | In-house | 3-263 (265) | Show / Hide |
Range on Protein: 160-412 Range on HMM: 3-263/265 Sequence Identity: 32% (84 aa) MQEFMALELKNLPGEFNSGNQPSNREKNRYRDILPYDSTRVPL---GKSKDYINASYIRIVNCGeeYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITR .|| ||. | . . .. .. ....||||.|. | .|| | . ..||| | |. . .| .|.|| .||.|||||| .. . | |. . | rdefralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnp--krficaqaPldktiadfwymvlqekveaivmlck EIEGGIIKCYHYWPISLKKPLELKHF--RVFLENYQILQ------YFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKShlTGP | | .|| .|.|.. .. ||.|. .. .||.. . .| || . .....|...|.|.|||.| |. . .. . .|.| .||.| liekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgs--kgP MVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIM-DIVAQMREQRSGMVQTKEQYHFCYDIVLEV ||||||||||| . .. . .... . . | ..| ..||||. .|||| | . ..|. ivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllny |
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| Phosphatase | PTPN20B.AA | Subfamily.RN.PD | 172-411 | 37 | 1.8e-50 | 163.0 | In-house | 16-261 (264) | Show / Hide |
Range on Protein: 172-411 Range on HMM: 16-261/264 Sequence Identity: 37% (94 aa) PGEFNSGNQPSNREKNRYRDILPYDSTRVPLGK-----SKDYINASYIRIVNCgEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCY | . .... | .|||....|||| .|| | . ..|||||| | . . |||||||| ||| |||||| |. . || ..|| ||. .|.. pstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdp-rapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqck HYWPISLKKPLELkhFRVFLENYQI-LQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHL--TGPMVVHCSAGIGRTGVF ||| .. .. . | | | . ...| | . . | . .| |. | ||..|.|||| |.... | ||. . |.|||||.| |||||.. rywpdeGsevyhi--yevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvy LCVDVVFCAIVKNC-SFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLE .|.| ..| .|. . .|.||.|.|.||.|..|.. | | ilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae |
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| Phosphatase | PTPN20B.AA | Subfamily.R_Nematode_2.PD | 182-405 | 31 | 7e-47 | 151.3 | In-house | 28-252 (261) | Show / Hide |
Range on Protein: 182-405 Range on HMM: 28-252/261 Sequence Identity: 31% (71 aa) SNREKNRYRDILPYDSTRVPL---GKSKDyINASYIRIvnCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLE ...|.|| |. ..|.| || . | | .. |.. .||||||| | .||| || .. . | |... .|.|| .|.|.. .. |.|..| lpkdkhRypdvPCkpetavevivdgkrvp-ihanwvpt--agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkld LKHFRVFLEN-YQILQYFIIRMFQVVEKSTG--TSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHltGPMVVHCSAGIGRTGVFLCVDVVFCAIVK .. . .||. | . ||.||| ....|. .|...|||.|.| | . . . ..||. |.|||||||||||. |. .... .. .. . lgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkkse--kPivvhCsaGiGRtmafigteylarevea NCSFNIMDIVAQMREQRSGMVQTKEQYHFC .. . ....||.|. .||..|... dptieltealkelrehRwkgiqtesqlywl |
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| Phosphatase | PTPN20B.AA | Subfamily.RC.PD | 206-411 | 31 | 5.5e-46 | 148.5 | In-house | 73-285 (288) | Show / Hide |
Range on Protein: 206-411 Range on HMM: 73-285/288 Sequence Identity: 31% (67 aa) KDYINASYIRIVNcgEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWpisLKKPLELKHFRVFLENYQILQYFIIRMFQVVEK .|||||.| . |||.|||| |.||||.|. |. .|| |.|. || || .|| . | |.. . .|.|....|.| skyinasfidsyk--kpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrekcaeyw---eeGkrayGdvevdlkdtdkssdyilrklelvnk STGTSHSVKQLQFTKWPDHGTPASADSFIKYIR------------YARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRS | | |.|.|.|.... |. ..| |. | | . ..|..|||..| .|||.|.... .. .. . ....| ..| .|..| krkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarp GMVQTKEQYHFCYDIVLE |...||| . ||.. | lmvsveeqyillydvlve |
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| Phosphatase | PTPN20B.AA | Subfamily.N_Nematode_6.PD | 182-413 | 28 | 4.5e-44 | 142.2 | In-house | 23-252 (253) | Show / Hide |
Range on Protein: 182-413 Range on HMM: 23-252/253 Sequence Identity: 28% (67 aa) SNREKNRYRDILPYDSTRVPLG-KSKDYINASYIRIvnCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELK .....|||..| .| .|. | . || |....| . .. .| ||.|| .||..||.|.| .. | |. .| | |. .| . . . . kfkdrnrytniqCcdagrlkladdedfyihanlvki--stkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarkit HFRVFLENY-QILQYFIIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKShlTGPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSF .. .. . . | ... |... . || ... .||||| | | .| .. . .|. .|.|||||||.|||| . . ... |. . . klctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkd--kkPivvhCsaGvGrtGtlaliliilealrlpdfq NIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL . |.....||.| |||. || . . ||| | gvkdllvklreerfravqtevqylyalrcvleyl |
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| Phosphatase | PTPN20B.AA | Subfamily.R_Nematode_3.PD | 181-412 | 22 | 5.1e-41 | 132.2 | In-house | 21-265 (267) | Show / Hide |
Range on Protein: 181-412 Range on HMM: 21-265/267 Sequence Identity: 22% (57 aa) PSNREKNRYRDILPYDSTRVPLGK-----SKDYINASYiriVNCGEEYFYIATQGPL--------LSTIDDFWQMVLENNSNVIAMITREIE---GGIIK . ...|. ... . .||| | . . |.|.|.. |.| .. | ||.|. |||. ||.|. ........|. .| .. || skkvsedrrvevpllektrvvLkgygkrfkddfihAnv---vecpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeek CYHYWPISLKKPLELKHFRV-FLENYQILQYF-IIRMFQVvEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHltGPMVVHCSAGIGRTGV .|.| . .. |... . | .. . |. . | ..| . . . |. |... |.....| ....... |....|| |.|||||.||.|.... cseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk--tpvvVHCsdGisRsat FLCVDVVFCAIVKNC-SFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEV ...... |.|. ........ ..|.|| | .||.... | ..|.. laaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkl |
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| Phosphatase | PTPN20B.AA | PTPc_motif | 312-411 | 44 | 1.8e-40 | 141.7 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 312-411 Range on HMM: 1-92/92 Sequence Identity: 44% (47 aa) SVKQLQFTKWPDH-----GTPASADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCY .|.....| |||| |.| ||....||. || |.|||||||.||||.| ..|.. . ..| ..| .||.|| |||||.||| ||| TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-----PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIFCY DIVLE ...|| RCILE |
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| Phosphatase | PTPN20B.AA | Subfamily.N_Nematode_5.PD | 181-411 | 27 | 2.7e-39 | 126.3 | In-house | 23-255 (258) | Show / Hide |
Range on Protein: 181-411 Range on HMM: 23-255/258 Sequence Identity: 27% (63 aa) PSNREKNRYRDILPYDSTRVPLGK-SKDYINASYIRIVNCGEeyFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCyHYWPISLKKPLEL .| .|||. |. .|.||| |.. ..|||||.|.. .. . .| || || .|. |||.||.... . . ..... |.. ...| . . |.|... . eknlkknrskdvkilDetrVkltdeddsYinaskiklddlek--kliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffpletgdylnl KHFRVFLENYQILQYF-IIRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIK-YIRYARKSHLT--GPMVVHCSAGIGRTGVFLCVDVVFCAIVK . . . ...|. .. . |. .| ..|.|... |.. || | ...|.||....|.||.| || ..|... . .. ..|| .|. gkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnn NCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLE ..|.|| |.|.. || . | .||. gkepnideilkkirsqRpgavesliqyasvyaavld |
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| Phosphatase | PTPN20B.AA | Subfamily.N_Fungi_PTP1.PD | 185-270 | 39 | 5.4e-28 | 89.3 | In-house | 47-149 (343) | Show / Hide |
Range on Protein: 185-270 Range on HMM: 47-149/343 Sequence Identity: 39% (40 aa) EKNRYRDILPYDSTRVPLG-------------KSKDYINASYIRIV----NCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYH ||||..||||. .|| | ...|||||.|... . .. |||||.|| ||.|||....|.|. .||..| ..| .. |||.|| aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr YWP . YWq |
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| Phosphatase | PTPN20B.AA | Subfamily.N_Nematode_egg.PD | 161-413 | 22 | 4e-23 | 73.5 | In-house | 4-256 (257) | Show / Hide |
Range on Protein: 161-413 Range on HMM: 4-256/257 Sequence Identity: 22% (58 aa) QEFMALELKNLPGEFNSGNQPSNREKNRYRDILPYDSTRVPLGK-----SKDYINASYIRIVNCGEEyfYIATQGPLLSTIDDFWQMVLENNSNVIAMIT ..| || .. . ..|| | . . .|.|| | . |.| | ... .| .| .| || | .|||.|| ... . | |.| rrfeilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllne--filaqaplkntvedfwrmvfqekvqyivmlt REIEGgiIKCYHYWPISLKKPLELKHFRVFLENYQILQYfIIRMFQVVE-KSTGTSHSVKQLQFTKWpDHGTPASADSFIKYIRYARKshLTGPMVVHCS | .| .||| . ...| . . .||... . .|.| . | |. . . |... | . | .. .| .|. |. |.||.. | sakes--erceyywpkaeseslvtvpGslrienlkvdsk-adplfrvtklklvGgddeelflehwqg-dvnylsdvysplrvlrklrn--lskpvvvqdi AGIGRTGVFLCVDVVFCAIVKNC--SFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVL . .......... .. ... . .. | .| .| |...| | | .|| . lGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlffi |
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| Phosphatase | PTPN20B.AA | Subfamily.N_Fungi_PTP1.PD | 304-410 | 27 | 1.6e-17 | 54.9 | In-house | 206-339 (343) | Show / Hide |
Range on Protein: 304-410
Range on HMM: 206-339/343
Sequence Identity: 27% (37 aa)
EKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIR--------YARKSHL----TGPMVVHCSAGIGRTGVFLCVDVVFC--AIVKNC------------
. . . | |||. .|.| .. |... . .||| . |..||||||.||||... .| .. |..|
taavsepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaak
-SFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVL
| || ..|.|| |||...|. |.|. .|
trDlisiivnelrkqrismvqnldqfifiYeall
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| Phosphatase | PTPN20B.AA | Subfamily.N_Nematode_eak.PD | 182-332 | 26 | 1e-16 | 52.5 | In-house | 25-175 (281) | Show / Hide |
Range on Protein: 182-332 Range on HMM: 25-175/281 Sequence Identity: 26% (40 aa) SNREKNRYRDILPYDSTRVPLGKSK----DYINASYIRIVNCGEEYfyIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLkKPL . ..|| .|.|.| | | |. ||||| . . |..| | | . . . |||||||..| | .. ..|.. | |.| . |. eavnrnrvvkivpqdrylvrltssqlnrdGyinaslaefsevGrky--iltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdkt-evl ELKHFRVFLENYQILQY-FIIRMFQVvEKStGTSHSVKQLQFTKWPDHGTPASADS .. | .| . . . |.... .| .| |. .. | . .| | kyGildverkeyavkrniletrllil-rkG-nethrvlhykvfGwtettlpkyedf |
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| Phosphatase | PTPN20B.AA | Family.DSP.PD | 241-402 | 12 | 8.8e-15 | 46.3 | In-house | 140-236 (387) | Show / Hide |
Range on Protein: 241-402 Range on HMM: 140-236/387 Sequence Identity: 12% (21 aa) QmvlennsnviamitreieggiikcyhywpislkkplelkhfrvflenyqilQ------YfiirmfqvvekstgtSHSVKQLQFtKWPDHGTPASADSFI . . . ....| |.. ..||..| .|.| t---------------------------------------------------ddkpqftk---------------elgikylri-pidDhnapplenlfe KYIRYARKSH-LTGPMVVHCSAGIGRTGVflcvdVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQY |.. ... .| .||| ||.||.|. .. . ..|. .. . .. .|..|.|... .... kaidfieegndskgvVlVHCkaGkgRsgt-----liiaYlmksegltleealdwvrskRpgvitpnqgf |
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| Phosphatase | PTPN20B.AA | Subfamily.DSP23.PD | 309-405 | 28 | 7e-12 | 37.0 | In-house | 27-120 (128) | Show / Hide |
Range on Protein: 309-405 Range on HMM: 27-120/128 Sequence Identity: 28% (28 aa) TSHSVKQLQF--TKWPDHGTPASAD--SFIKYIRYARKShlTGPMVVHCSAGIGRTGVFLCvdvvfCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHF |.....| . . ||. || ... . | |. ... ||| |.|||| .| | .||. . | .|..|..| |..|.|| . yseaapsltlrridipdfcPPaleqvarlvriveeaekk--eeavgvhcalGlGrtGtlla-----cylvkeeglaaddaiaevrkrrkGsietveqeka C v |
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| Phosphatase | PTPN20B.AA | Subfamily.PTPDC1.PD | 320-407 | 24 | 9.4e-12 | 36.2 | In-house | 141-222 (229) | Show / Hide |
Range on Protein: 320-407 Range on HMM: 141-222/229 Sequence Identity: 24% (21 aa) KWPDHGTPaSADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAivkncSFNIMDIVAQMREQRSGMVQTKEQYHFCYD ..|.|.. | .. . .. . . . | . ||| || ||||| .. .|. .. . . ..|..|. .||.|| ... . glkDygva-sleriLdivkvvdfaleegkiavHCHAGlGRtGvliacylvyak-----rltaeeaiklvrskrpksiqtreqvelvee |
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| Phosphatase | PTPN20B.AA | Subfamily.CDC14.PD | 343-404 | 31 | 8.7e-11 | 33.3 | In-house | 195-250 (258) | Show / Hide |
Range on Protein: 343-404 Range on HMM: 195-250/258 Sequence Identity: 31% (19 aa) SHLTGPMVVHCSAGIGRTGVFLCvdvvfCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQyHF . .| ..||| ||.||||... | ..|. |. ...| .| | |.| .. | .. ekaeGaiavhCkaGLGrtgtlig-----cylikhyrftaaetiawlriarPGsvigpqq-ty |
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| Phosphatase | PTPN20B.AA | Subfamily.N_Nematode_eak.PD | 349-414 | 26 | 6e-09 | 27.0 | In-house | 214-281 (281) | Show / Hide |
Range on Protein: 349-414 Range on HMM: 214-281/281 Sequence Identity: 26% (18 aa) MVVHCSAGIGRTGVFLCVDVVFCAIV--KNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLR .. .. | |.|||. .|.. | |. .. . |.. .....| | .. |. | |.|||. |. piiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyll |
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| Phosphatase | PTPN20B.AA | Subfamily.RC.PD | 176-202 | 48 | 1.4e-07 | 22.4 | In-house | 19-45 (288) | Show / Hide |
Range on Protein: 176-202 Range on HMM: 19-45/288 Sequence Identity: 48% (13 aa) NSGNQPSNREKNRYRDILPYDSTRVPL . .... |..|||| |.|||| ||.| kiarkeenksknrysdvlpydynrvel |
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| Phosphatase | PTPN20B.AA | Subfamily.PTEN.PD | 283-396 | 21 | 2.7e-07 | 21.6 | In-house | 32-143 (305) | Show / Hide |
Range on Protein: 283-396 Range on HMM: 32-143/305 Sequence Identity: 21% (25 aa) RVFLENYQILQYFIIRMFQVVEKSTGTSHSVKQLQFTkwpDHGTPAS--ADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSfN ...| |. . . | .. .... .. |.. |. || | .... . |. . ..||| || ||||| .| ...| |. . . . illltvykgkgklrilnargekedsdfdgrvavypfd---DhnpptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksad-e IMDIVAQMREQRSGMV .| ...| . . | alaiydekRtkdkkGV |
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| Phosphatase | PTPN20B.AA | Subfamily.PRL.PD | 314-400 | 21 | 4.4e-07 | 21.2 | In-house | 45-129 (140) | Show / Hide |
Range on Protein: 314-400 Range on HMM: 45-129/140 Sequence Identity: 21% (19 aa) KQLQFTKW--PDHGTPAS--ADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVfcaivkNCSFNIMDIVAQMREQRSGMVQTKE .... . . | ..|.. |.... .. . | . . ||| ||.||. |.... .. .. .. | | .||.| | . .| egievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalali------eaGmkyedavefirekrrgainskq |
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| Phosphatase | PTPN20B.AA | Subfamily.PTPMT1.PD | 309-402 | 22 | 5.5e-06 | 17.7 | In-house | 49-137 (146) | Show / Hide |
Range on Protein: 309-402 Range on HMM: 49-137/146 Sequence Identity: 22% (21 aa) TSHSVKQLQFTKWpDHGTPASADSFIKYIRYARKSHLTGPMV-VHCSAGIGRTGVflcvdVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQY ... |.|||.. . |.. .| .. . ... | . | | ||| || .| . .| | ..|. .. . | ....|. ...|. kklGveqlqlatv-DfteapslekleegvefiekvaskgssvYvHCkAGrtRsat-----lvacylmkkkklspeeavkflkkkRpqirlkskqw |
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| Phosphatase | PTPN20B.AA | Subfamily.DSP19.PD | 314-393 | 22 | 9.3e-06 | 17.0 | In-house | 49-121 (139) | Show / Hide |
Range on Protein: 314-393 Range on HMM: 49-121/139 Sequence Identity: 22% (18 aa) KQLQFTKWPDHGTPASADSFIKYIRYARKSHltGPMVVHCSAGIGRTgvflcVDVVFCAIVKNCSFNIMDIVAQMREQRS |... |.. . .. ...|. ||... | ..|||.||. |. . || ..|. . .. . . ..||.| ksieilDlpetkllsylkealdFieearskd--grvlvHCnAGvSRs-----asvviaylmkdeelslekalekvrearp |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| PTPN20B.AA | Protein | None | 420 | None | Fasta, JSON |
| PTPN20B.NA | RNA | None | 1260 | None | Fasta, JSON |
| PTPN20B.AA.PD_158-414 | Protein Phosphatase Domain | None | 257 | None | Fasta, JSON |