Gene PTPN23
PTPN23
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTPN23.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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BRO1 | PTPN23.AA | BRO1 | 8-384 | 36 | 6.4e-170 | 575.6 | Pfam | 1-420 (420) | Show / Hide |
Range on Protein: 8-384 Range on HMM: 1-420/420 Sequence Identity: 36% (155 aa) PMIWLDLKEAGDFHFQPAVKKFVLKNY-GENPEA---YNEELKKLELLRQNAVRV--PRDFEGCSVLRKYLGQLHYLQSRV--PMGSGQEAA-VPVTWTE ||||. ||.. .. . ..|......| |..|.. |......|. |||.|... ....|...| .|.|||..|..|. |.. ... . |. ||.. PMIWIPLKKTKEVDWTKPLKNYIKNHYSGQDPWMQFYYEDDCAELNQLRQDARNPCPSPHESGLELLYRYYGQLCWLEKRFFPPFH-DDRHIGVEFTWYD IF----SGK-----SVAHEDIKYEQACILYNLGALHSMLGAMD----KRVSEEGMKVSCTHFQCAAGAF---AYLREH----FPQAYSV-DMSRQILTLN | .|. .|.. ....|.||.|.|.|||.| ..|. | ..||.| .|..||.|||.| .||.|. | .| || |||.. | AFDHRSHGSSFGRRPVCQNNLAFEKACVLFNIGALYSQIAASQYESDNRDTDEGLKQACHYFQQAAGCFDCAQYLNENVPAEFLHAPSVYDMSPETLKCL VNLMLGQAQECLLEKSML---D-NRKSFLVARISAQVVDYYKEACRALENPDTASLLGRIQ-KDWKKLVQMKIYYFAAVAHLHMGKQA--EEQQKFGERV |||||.|||||...|... | ..| |.|...|||.|||.|..||. . ... ... |.|...||.|...|.||||....... ||..|.||.. VNLMLAQAQECFWQKAINQDIDMGMKDSLIAKLAAQVSDYYQECHRAMQKSPYKCY--YWPWKEWIHHVQCKQHHFKAVAHYYHALHCCDEEKKKYGEAI ---AYFQSALDKLNEAIKLAKG--QPDTVQDALRFTMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPVNPTD-----PAVTGPDIFAKL |..| |...|.||.|..|. ... .||.|....|.|. |...|.||||||||| || ...| |.|....|||.|.| .. .....||.|.|| DLKAHLQHAQQCLKEAQKKHKKCYVNY-LQDDLKYLHDRIQEKLKRAEKDNDFIYHEPVPDEVSLPPIKPMDMVKPIPWNEVFEPQEATKHKCPDLFKKL VPMAAHEASSLYSEEKAKLLREMM |||| |||.|.|||.|.|..|. VPMAVHEAASIYSERKDKYVRNEI |
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Phosphatase | PTPN23.AA | Subfamily.N23.PD | 1189-1453 | 43 | 6.30000000001e-106 | 345.4 | In-house | 38-349 (350) | Show / Hide |
Range on Protein: 1189-1453 Range on HMM: 38-349/350 Sequence Identity: 43% (135 aa) GALDTVWRELQDA--QEHDARGRSIAIARCYSLKNR--HQDVMPY--------------------------------DSNRVVLR-----SGKDDYINAS |. .|.|.||.|. ||..|. .|||.|...| ||| ..|..|| |.|||.|. ..||||||.. gpvetlwseledyqgqeaiaadqsiasakrmsnknrqfnpdllpyhlqpttitavpqprhlqtegsGqqqgtpdsrhdpnrvklqqstqpgqqddyinat CVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSL .. |.|..||..|||.|.. |.|||||||.||..||||||..|.|..|.|...|.|...|.....|.|...|.|.||.|...||||.||..|.| .|... ylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrssegwiervlhlqhndvstvrlv VHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQRPLHT------PIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLH |||. ||.|.|.|.||..||.|..||...| .|| .| |||.|||.||||||.|...|.|..|..|||||...|..|||.|||||.|.|.| .| chlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvi LRFCYEAVVRHV ...||||.... lkklyeavleaa |
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Phosphatase | PTPN23.AA | PTPc | 1190-1454 | 27 | 6.8e-94 | 319.16 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 1190-1454 Range on HMM: 1-308/308 Sequence Identity: 27% (87 aa) ALDTVWRELQDAQEHDAR-----GRSIAIARCYS----LKNRHQ-DVMPYDSNRVVLRS--------GKDDYINASCVEGLSPYCPPLVATQAPLPGTAA . . . .||... .|. .|. .|. . |||.. |...||..||.| . . .|||||. ..| .. .||.|||.| . GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-WRPKRYICTQGPLPHTIE DFWLMVHEQKVSVIVMLVSEAEM--------EKQKVARYFPTERGQPMVHGALSLALSSVRSTE-THVERVLSLQFRDQ--------SLKRSLVHLHFPT ||| || .||...||||... |. . | ..|.| | ||..| ... . |. ... . |...... .. | .|.. |.|... DFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTN WPELGLPDSPSNLLRFIQEVHAHYLHQ----------------RPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQE ||..| |.||. .|.||..|.... |. .. ..||.|||| |.||||.|... ...| .|. . ..|.|..||.|| .| | WPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN----VDIFQIVKMMRNQRPGMVQT KLHLRFCYEAVVRHVE . ...|||... . .. EEQYIFCYRCILEYIK |
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Phosphatase | PTPN23.AA | Y_phosphatase | 1217-1451 | 33 | 2.3e-92 | 317.94 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 1217-1451 Range on HMM: 1-243/243 Sequence Identity: 33% (83 aa) YSLKNRHQDVMPYDSNRVVLR----SGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEK-QK-VARYFPT-ERGQ |||. |. .||..||.| . .|||||. ..| .... .||.|.| | .||| || .||...|||| .. ||.. .| ..|.|. ..|| NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ PMVHGALSLALSSVRSTETHVERVLSLQFRDQ--SLKRSLVHLHFPTWPELGLPDS-PSNLLRFIQEVHAHYLHQRPLHT--PIIVHCSSGVGRTGAFAL ||..| .. . |. ... . |...... . . .|.. |.|...||. | |.| | ..|.||..|. .. .| | ||.|||| |.||||.|.. PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP--NPDHGCPPIVVHCSAGCGRTGTFCA LYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVR . .. | .|... . ...|.|..||.|| .| | ...|||.... IDIMCQQMEHEGTV-DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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Phosphatase | PTPN23.AA | Subfamily.N3.PD | 1219-1452 | 35 | 1.7e-57 | 185.7 | In-house | 28-259 (261) | Show / Hide |
Range on Protein: 1219-1452 Range on HMM: 28-259/261 Sequence Identity: 35% (83 aa) LKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPY---CPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTeRGQPMVHGA |||..|..|||. || |.... |||||. |. .| .||| ||. ||.||| ||.|||...|||| . | ..| .|.|... . .| .|. aknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqyWPe-tedelefge LSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYlhqRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAG ... ..|...| | | |. .... .|....| . ||. |.||.....|.|...|.. . ..|..||||.|.|||| . || |.. .|| . . fsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr---sgkeePvvvhCsaGigrtGvlilletalalieaa NGIPELpQLVRRMRQQRKHMLQEKLHLRFCYEAVVRH | ..||.||.||. ..| . .| ||... epvypl-divrtmrdqramlvqtvsqykfvCeailka |
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Phosphatase | PTPN23.AA | Subfamily.RB.PD | 1211-1451 | 32 | 5e-56 | 181.1 | In-house | 20-258 (261) | Show / Hide |
Range on Protein: 1211-1451 Range on HMM: 20-258/261 Sequence Identity: 32% (79 aa) IAIARCYSLKNRHQDVMPYDSNRVVL----RSGKDDYINASCVEGLSPYcPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTE | ... . |||.. ..|||..|| | . ..|||||. ..| . .||| |||.| ||| ||.|.|.|.||||. | |.|. .|.|... aaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynsp-reyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYWPad RgQPMVHGALSLALSSVRSTETHVERVLSLQFRDQslKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYlHQRPLHTPIIVHCSSGVGRTGAFALLY .|...| ... | . ......| | .... ... ||.. ..|| .||. | |.... ||.|...|. . .... ..||.|||| ||||||.| | e-epvlyGdikvtllaekeldewvirefkiekgke--krkvrqyhftsWpdhgvPektktlldfvrtvreai-ekkaskkPivvHCsaGvGRtGtfiald AAVQEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVR .|..|. . . .. .| ..|..|....| . . | .|.... rllqaieendyv-dvfgvvaelReeRnllvqtekqyifiheclld |
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Phosphatase | PTPN23.AA | Subfamily.R_Anemone_2.PD | 1195-1453 | 32 | 3.2e-55 | 178.6 | In-house | 6-261 (262) | Show / Hide |
Range on Protein: 1195-1453 Range on HMM: 6-261/262 Sequence Identity: 32% (85 aa) WRELQDAQEHDARGrSIAIARCYSLKNRHQDVMPYDSNRVVLRSGK----DDYINASCVEGLSPYcPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVS . .|. ..|. . . |. . |||......||. || |. . |||||. ..| .||||||| | ||| || ||. .||||| yerlsrseetsvtl-ksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrk-kayiatqaPlpetiedfWrmvWeqnsavivmltq EAEMEKQKVARYFPTErgQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAhyLHQRPLHTPIIV | | |.||.||.| . ... .|.| |.. .....| | .... ... .| . |. .||. |.|.|...|| ....|.. .|.. ..||.| eeergkakvhryWPsk--gsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvek--aqqesgagpivv HCSSGVGRTGAFALLYAAVQEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV |||.|||||| | . . .. ..| . . .. | |...|.||. |.| ||.|.... . hcsaGvGrtGvfiavdillerikaealv-dvfqtvkqlreqrnlmvqtkdqyefiydvlleal |
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Phosphatase | PTPN23.AA | Subfamily.N_Choan_1.PD | 1215-1452 | 33 | 3.7e-54 | 175.0 | In-house | 24-260 (262) | Show / Hide |
Range on Protein: 1215-1452 Range on HMM: 24-260/262 Sequence Identity: 33% (79 aa) RCYSLKNRHQDVMPYDSNRVVL----RSGKDDYINASCVEGLSPYcPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPtERGQP ||||..... || || . .. . |||||. |.|.. .|||.|.| . ..|| || |||||.|||. | | .| | ||.| . . . | denvlknrysnivayDatrvkvtpneenkntDyinanfvpgykge-keyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWP-dense MVHGALSLALSSVRSTETHVERVLSLqFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHylHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQ . . | ....|..||...| |... .|....|.. .||. | |.....|| | ..|. ... ..|...|||.||||||.. | .|..||. lklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlka--tkkktkaplvihCsaGvGrtGtyialDrlvk EVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRH . ... ..|. .|..|. |.| . .| | || . aveekaealdvkavvaelrkernlmvqtlvqyefvykavlda |
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Phosphatase | PTPN23.AA | Subfamily.N13.PD | 1215-1451 | 34 | 5.7e-54 | 174.4 | In-house | 24-256 (259) | Show / Hide |
Range on Protein: 1215-1451 Range on HMM: 24-256/259 Sequence Identity: 34% (81 aa) RCYSLKNRHQDVMPYDSNRVVLRSGKDdYINASCVEGL-SPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPM-V . |||...|.||| || | . ||||| .. .|.| ||| |..|||.|| |||..||.|. .| | .| | ||.|...... |. kenkdknryrnvlPydetrvklgdegg-yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerknkklkv HGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAhyLHQrpLHTPIIVHCSSGVGRTGAFALLYAAVQEV . | ..| | .. | | | .. . . | ..||.| .||. | | |. .|..|..||. |.. ..||.||||.|.||.|.. ...... .| snrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrl--lqt--dagPivvhcsaGiGrsGvlitidvvlgli EAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVR . . .. ..||..|.||. ..| | |.|.|.. erdkef-dvkeivrklreqrqgvvqtkdqyifvykaile |
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Phosphatase | PTPN23.AA | Subfamily.N9.PD | 1198-1452 | 32 | 4.4e-53 | 171.6 | In-house | 6-273 (275) | Show / Hide |
Range on Protein: 1198-1452 Range on HMM: 6-273/275 Sequence Identity: 32% (87 aa) LQDAQEHDARGRS-IAIARCYSLKNRHQDVMPYDSNRVVLRSGK----DDYINASCVEGLSPYcPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEA .| ..... |. . |. . |||..||. ||. ||.| . . |||||. |.| ..||| ||. | |||.|| ||.| |||| | yadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqk-kafiatqGplkktvsdfwrmvweqevlvivmttrvv EMEKQKVARYFPTERGQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAH------YL----HQR . . | ..|.|.|... . .| ||.. .|...| ...||| .. ... .|...| | .||. | |.| ..|| ....|. .| . .. ergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskgh PLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRH ||.||||.|.||||.|. | .....| . . .. . |...|.|| ...| . ||| ||. . lsgPPivvhcsaGiGrtGtfitldiclarleevgtv-dvvetvkllrtqrafsiqtpeqyefcylavley |
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Phosphatase | PTPN23.AA | Subfamily.R_Anemone_1.PD | 1199-1452 | 32 | 6e-53 | 171.2 | In-house | 7-256 (258) | Show / Hide |
Range on Protein: 1199-1452 Range on HMM: 7-256/258 Sequence Identity: 32% (82 aa) QDAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSG----KDDYINASCVEGLSPYcPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEM | .|... ..| .. |||..|....|. ||||.. . |||||| ... . .||||||. | .||| ||..|..||||| . |.| qrlkeikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdkt-rafiatqapleetvedFWrmvwqekigviVmLtnlieg EKQKVARYFPTergQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHylhQRPLHTPIIVHCSS |.|. .|.|. .. .| |.. | . . | | |. .... .| .|..|| .||. ||. .|.. ..|... ... ..|..||||.|| ekkkchqYwPd---stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks---slagarpvvvhCsa GVGRTGAFALLYAAVQEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRH |||||| ..| .. . . . . .. . |...|..| ||.| ||...||.. GvgRtGaflvidamleqakkekvv-Difnyvkairedrphmvqtkeqyvfihlavlea |
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Phosphatase | PTPN23.AA | Subfamily.R_Sponge_2.PD | 1210-1453 | 33 | 6.8e-53 | 170.9 | In-house | 18-261 (262) | Show / Hide |
Range on Protein: 1210-1453 Range on HMM: 18-261/262 Sequence Identity: 33% (81 aa) SIAIARCYSLKNRHQDVMPYDSNRVVLRS---GKDDYINASCVEGLSPYcPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTE ||| . |||.....|||..|| ||. . |||||| |.|. .|||.||. |..||| || |.||| ||||.| .|.| |.|.|.. .. siaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrr-kayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPek RGQPMVHGALSLALSSVRSTETHVERVLSLQFRDQS-LKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHylHQRPLHTPIIVHCSSGVGRTGAFALL . | .| . . .. .. | | |. ...| .. . . || .||| . |.. . || .|..|. . ... ..|.|.|| ||||||.| |.. vdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlra--qkksgnkaitvvCsdgvgrtGtfial YAAVQEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV .. ..| . | .. .... .| .| ..|.. . |...|. . dsvlerlkaeeei-dvfevlktlrtkriglvqdaaqYvfihdalleyi |
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Phosphatase | PTPN23.AA | Subfamily.N12.PD | 1212-1453 | 30 | 3e-52 | 168.5 | In-house | 27-269 (270) | Show / Hide |
Range on Protein: 1212-1453 Range on HMM: 27-269/270 Sequence Identity: 30% (76 aa) AIARCYSLKNRHQDVMPYDSNRVVLRSG----KDDYINASCVEGLSPYCpPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTER . . |||..|..||| .||.|. ..|||||. ..| . . .|.|.||| | ||| |. |..|...||. | |..|.|.||.| | . gekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkl-eyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpeeg GQPMVHGALSLALSSVRSTE-THVERVLSLQFRdqSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQrplHTPIIVHCSSGVGRTGAFALLY ... .|.....|.. . .. .. | | .... . .|.. .|. ||. | | |...||..|..|. . .. ..|..||||.||||||. . eeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqese---daPlvvhCsaGvGrtGtiiaid AAVQEVEAGNGIP--ELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV . . ..|.. . .. .|| ..|.||. . | | .. |.||. | yvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv |
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Phosphatase | PTPN23.AA | Subfamily.N5_RR.PD | 1218-1452 | 30 | 4.8e-50 | 161.5 | In-house | 24-263 (265) | Show / Hide |
Range on Protein: 1218-1452 Range on HMM: 24-263/265 Sequence Identity: 30% (75 aa) SLKNRHQDVMPYDSNRVVLRS--GKD---DYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQ--P . |||.....| . ||.|.| ..| .|||| . | . |||| ||| | ||||.|.....|.||||| |...|| |.|||.... qtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeis MVHGALSLALSSVRSTETHVERVLSLQFRDQsLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQ .| ... ... ... . | |.|.. . ..||..| .. ||. ||....||....||. .. .|..||||.|.||||.| ||. erygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavr EVEAGNGIPELpQLVRRMRQQRKHMLQEKLHLRFCYEAVVRH .... . . | ..| ..|..| |.|.. .. ..|.. . qlreeivvdvl-kivcnlrldrGGmvqtseqyelihralcly |
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Phosphatase | PTPN23.AA | Subfamily.RA.PD | 1219-1453 | 32 | 3.6e-48 | 155.3 | In-house | 29-265 (266) | Show / Hide |
Range on Protein: 1219-1453 Range on HMM: 29-265/266 Sequence Identity: 32% (79 aa) LKNRHQDVMPYDSNRVVLRS--G--KDDYINASCVEGLSPyCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTErGqPMVHG ||| ...||| .||.| | . |||||| ..| .|.| |. | ||| |. ||| . |||| | ...| |.|.|.|| . .| . kknrvvqilpydfsrvilsvkeGeeesdyinasfidGyre-kdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqywpde-G-lvtyG ALSLALSSVRSTETHVERVLSLQ----FRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHylHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQ ... . .|. | . .. ... .| . .|| .|||.|.| .. .|.....|.. .|. ||.||||.||||||.| | | .. | eirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkkl--qqqsanhpivvhcsaGvGrtGtfivldavle EVEAGnGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV .| .. .. . |.|.|.|| .|.| . |.|... .. rvkae-rkldvfeavkrlrlqrpqmvqtleqyefiykvlleyi |
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Phosphatase | PTPN23.AA | Subfamily.N6.PD | 1196-1453 | 29 | 4e-48 | 155.3 | In-house | 19-294 (295) | Show / Hide |
Range on Protein: 1196-1453 Range on HMM: 19-294/295 Sequence Identity: 29% (80 aa) RELQDAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSG-----KDDYINASCV--------EGLSPYCP----PLVATQAPLPGTAADFWLMVH ||| . .. |. . . ||| ....|.| .||.|. | .|||||. . .| .. . .||| .|. |.||| ||... eelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvw EQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMvHGALSLALSSVRSTETHVERVLSLQFR-DQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAH . ||||. | | |.| |||.|.|. . .| ... | .||.. . | .|.. . ... .|.....|| .||. | |.|. .| |...|.... . qensrvivmttkevergknkCarYWPdeetkke-tGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkk YLHQrPLHTPIIVHCSSGVGRTGAFALLYAAVQEV---EAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV . ||.||||.|.||||.| .. . .. . . | .. . ....|.|| ..| . ..| | ||.. qeel-ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdi-disksikdvrsqrsglvqteaqykfvykavqfyi |
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Phosphatase | PTPN23.AA | Subfamily.R_Ecdysozoa.PD | 1217-1451 | 30 | 9.9e-47 | 150.4 | In-house | 27-266 (269) | Show / Hide |
Range on Protein: 1217-1451 Range on HMM: 27-266/269 Sequence Identity: 30% (73 aa) YSLKNRHQDVMPYDSNRVVLRS----GKDDYINASCVEGLSPYcPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQkVARYFPTErgQPMV ||||..|....|..||.|. . |||||| ..| .| |.|. .|. ||| |. ||.| .|||| . |.... .|.|.| | . . .| nalknryedikafDktrvkLkkingkedsdyinasfikgykek-kkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknrk-cakyWpie--devq HGALSLALSSVRSTETHVERVLSLQFRD---QSLKRSLVHLHFPTWP-ELGLPDSPSNLLRFIQEVHAHYLHQ--RPLHTPIIVHCSSGVGRTGAFALLY . | | .... ...| |.. . .| .| .. .|. . |... ||..|..|. .| .. ..||.|||| ||||.| | | ygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgrsgifvald AAVQEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVR .|...| . . .. . |. .|.||. ..| |.| |.. lllqqlkaedkv-difetvkkLrsqrnllvqsleqyvflyralad |
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Phosphatase | PTPN23.AA | Subfamily.RG.PD | 1192-1451 | 26 | 1.3e-45 | 147.0 | In-house | 3-261 (264) | Show / Hide |
Range on Protein: 1192-1451 Range on HMM: 3-261/264 Sequence Identity: 26% (71 aa) DTVWRELQDAQEHDARgRSIAIARCYSLKNRHQDVMPYDSNRVVLRS--GK--DDYINASCVEGLSPYcPPLVATQAPLPGTAADFWLMVHEQKVSVIVM . ..|.| ...| . . . ... . |||. ....... || |.. || .|||||| ..| ..|| ||. |. ||| |. |.....||| eeqfeeiqklkpkdie-aesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrs-keyivtqgplketiedFWrmiWehnaqiivm LVSEAEMEKQKVARYFPTErGQPMVHGALSLALSSVRSTETHVERVLSLQFR--DQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVhahYLHQRPLH | . | ......|.|.. .|. .||.. | | ... . | ..|. . |....| ..|...||. | |.| . ||.. .. ltdldekgrrdedvyWPkk-deplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkke---eaankeea TPIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVR ||.||.|.||||.| . | . .|..|. . . .. |.....|..| ...... .| |.|.. GPivvhdsaGvgragtyialdtllqqlekeeav-nvyqvlklirakRpglvtteEqyvfiydalle |
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Phosphatase | PTPN23.AA | Subfamily.N_Choan_2.PD | 1220-1453 | 28 | 1.5e-45 | 146.5 | In-house | 24-265 (266) | Show / Hide |
Range on Protein: 1220-1453 Range on HMM: 24-265/266 Sequence Identity: 28% (68 aa) KNRHQDVMPYDSNRVVLRSGKDD----YINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGA ||..|..| ||.| . ..| |||| |.| . .|...||| | .|| |. |.||. |||. | ..| .||.|.|... . . lnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvklad LSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPS------NLLRFIQEVHAHYLHQRPLHtPIIVHCSSGVGRTGAFALLYAAV .. .. .. .. .. |. . .. .|.||| .. |||. | | .. .||. ...|...... . |..|||| |||||| . .. ||. . gkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkae-PllvHcsaGvgRtGtliaiDiav QEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV | . . .. ......|..| ..| . .. |.||| .. rlLeetkkv-dvlaiieelRkdRmalvqhpeqyellykavveya |
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Phosphatase | PTPN23.AA | Subfamily.N14.PD | 1217-1453 | 30 | 3.7e-45 | 145.4 | In-house | 26-274 (275) | Show / Hide |
Range on Protein: 1217-1453 Range on HMM: 26-274/275 Sequence Identity: 30% (74 aa) YSLKNRHQDVMPYDSNRVVLRSGKD---DYINASCVE-GLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTE--RGQP |||..||.||. ||| | . |. .||||| .. .. ...|.||. | ||| || ||.|..|||| .| | |.| .|.| . . . . . naeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeksfkylPkleskkkt MVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQRP-------LHTPIIVHCSSGVGRTGAFA | . ...... . . | |.. . .|...|| . ||. |.|. ....| |..||.. . .|..|||| |||||| | vefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtGvli LLYAAVQEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV .. .| .. | .... ..|.|.|| ...| .| |....... lsdlliatlehneei-dikkvlarLrkqrmllvqtlaqykfvykvlikyl |
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Phosphatase | PTPN23.AA | Subfamily.N1.PD | 1220-1451 | 32 | 6.4e-45 | 144.8 | In-house | 31-265 (268) | Show / Hide |
Range on Protein: 1220-1451 Range on HMM: 31-265/268 Sequence Identity: 32% (75 aa) KNRHQDVMPYDSNRVVLRSGKDDYINASCVEgLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQ-PMVHGALSL .||..|| ||| |..|.... |||||| || | . || ||| || || || ||. ..|| | ...| | |.|.|. ... .| . lnryrdvspydhsrikleradvdyinaslve-leeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqeeeeaellleetkl ALSSVR--STETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQrPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGN .. .. .. | | |. ... | ..| |. |||..|.|.||. .|.|...|. . . . ..|...|||.|.||.|...|. . . |.|. . kvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLs-sdvgpavihCsagigrsgtlslvdtclveiektg G--IPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVR .. . . .|..| ..| ||| | |.. dlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile |
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Phosphatase | PTPN23.AA | Subfamily.RN.PD | 1193-1453 | 34 | 3.6e-44 | 142.1 | In-house | 4-263 (264) | Show / Hide |
Range on Protein: 1193-1453 Range on HMM: 4-263/264 Sequence Identity: 34% (90 aa) TVWRELQDAQeHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRS----GKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVML | | . . . . ...| | . |||...|.||| .|| |.. |.|||||| . | | .|||.||. | |||| || ||| |||.| . kewealcaye-aepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnl VSEAEMEKQKVARYFPTErGQPmVHGALSLALSSVR-STETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYlhqRPLHTP .| . ....||.| | |. |... . | | .. .. | . |. ..| |.. .|| .||| | | |. .|| |. | | | .||.|| trleeegvkqckrywpde-Gse-vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksy---rGrscp IIVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV ||.|.||||.. |. .. . | .. . .|.||..... | ..|.. ||.. | ivvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeev |
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Phosphatase | PTPN23.AA | Subfamily.RK.PD | 1206-1451 | 26 | 5.9e-41 | 131.5 | In-house | 18-264 (267) | Show / Hide |
Range on Protein: 1206-1451 Range on HMM: 18-264/267 Sequence Identity: 26% (66 aa) ARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGK---DDYINASCVEGLSPyCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSE-AEMEKQKVAR . .|| ||| .|...|| .|.| | . |||||. ... ..|| ||. | .||| .|.... . |||| |. | .|. sedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsykr-paafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClk YFPTERGqpMVHGALSLALSSVRSTETHVERVLSLQF--RDQSLKRSLVHLHFPTWPEL-GLPDSPSNLLRFIQEVHAHYLHqrPLHTPIIVHCSSGVGR | . . .| . . | .. . | |..... | |. .| . ...| .||| . |.| ||..|..|... .. .|.|||..| ||.|.| yWPedte--vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee--eeeGrivvhClaGaGr TGAFALLYAAVQEVEAgNGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVR . .. .| .|. .. . |. .|... |.. . .|.|.... sGtfiaidivlemier-egvvdvfnavktlrnrkvnmveteeqykfvydvile |
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Phosphatase | PTPN23.AA | Subfamily.N_Nematode_5.PD | 1220-1453 | 29 | 2.6e-40 | 129.3 | In-house | 28-257 (258) | Show / Hide |
Range on Protein: 1220-1453 Range on HMM: 28-257/258 Sequence Identity: 29% (68 aa) KNRHQDVMPYDSNRVVLRSGKDDYINASCVEgLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVaRYFPTERGQPMVHGALSLA |||..||. .|..|| | ..|.||||| .. | |. || ||| |..||| ||...|. .|.||.. |.....|.||.| |. . .| . knrskdvkilDetrVkltdeddsYinaskik-lddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffpletgdylnlgkmfin LSSVRSTETH-VERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLR-FIQEVHAHYLHQRplhTPIIVHCSSGVGRTGAFALLYAAVQEVEAGnG | . |.. | .. . ..| . . . |. ||.. ||. ..... |..|. .. ..|..|....|.||.| |.|| .|......| |.. . nrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgkn---apvvvvsdlGlgRagtflllsvaieqlnng-k IPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV ... .|.|| .. .. . . |.||. .. epnideilkkirsqRpgavesliqyasvyaavldyi |
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Phosphatase | PTPN23.AA | Subfamily.N_Nematode_1.PD | 1219-1446 | 31 | 4e-38 | 122.3 | In-house | 28-257 (265) | Show / Hide |
Range on Protein: 1219-1446 Range on HMM: 28-257/265 Sequence Identity: 31% (74 aa) LKNRHQDVMPYDSNRVVL--RSGKDDYINASCVeGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGAL |||..|| | |||.| . ||| | | | . .. .|||| | |||| || .|| |||| |. |.|| |||...|. .. dknrykdvgcldknrvklaeeplpsdyihanyv-gtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegeklefkek --SLAL---SSVR---STETHVE-RVLSLQFRDQsLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVhahylhqRPLHTPIIVHCSSGVGRTGAFALLYA ... ..|. ..| .. ||.... . .|.. |... ||. | | | ....| |. ..||.||||.|.||||. . . gqkitvenslgvkkleedeevikvtvlevegaGe-ktrkvthyqWtdWPdrGvPpadlaalelleav-------rgskgPivvhCsaGiGrtGtivaiey AVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLRFCY ... .|. |.. ..||...|.||.. .| | . ildkllegkqiedmeklvkkireqrnysiqtdaqylfvh |
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Phosphatase | PTPN23.AA | Subfamily.RC.PD | 1218-1451 | 30 | 4.6e-36 | 115.6 | In-house | 27-285 (288) | Show / Hide |
Range on Protein: 1218-1451 Range on HMM: 27-285/288 Sequence Identity: 30% (78 aa) SLKNRHQDVMPYDSNRVVL---------------RSG--------KDDYINASCVEGLSPyCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEM |||. ||.||| ||| | | .||||| ... ..|.| || | ||| |..|.|| ||||| | .. ksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykk-pekyiaaqGplketvddfwrmiferkvkvivmltelkeG EKQKVARYFptERGQpMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQRP-------LHTP .| |.|. | |. .| . . | . ... |.| |. . . | .... . .|.. .||. | .||..|| |. ...| ||..|| drekcaeyw--eeGk-rayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstp IIVHCSSGVGRTGAFALLYAAVQEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVR |..|..||| | | | .. .|| . . .. |.|...|..| |.. . . |...| llvhcrdGsqrtGifiallallesleaeekv-dvfqvvkklrkarplmvsveeqyillydvlve |
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Phosphatase | PTPN23.AA | Subfamily.N_Nematode_4.PD | 1216-1446 | 27 | 1.5e-34 | 110.7 | In-house | 25-256 (264) | Show / Hide |
Range on Protein: 1216-1446 Range on HMM: 25-256/264 Sequence Identity: 27% (65 aa) CYSLKNRHQDVMPYDSNRVVLRSG--KDDYINASCVEglSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVH | |||..|.. | .||||. . ||| || . | ..|| ||. | .||| ||...|..|.||| . | ..| |||.| . .. ...| knsdknryadilcidetrvvlknrdpdndyihaswmr--mPdkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkf GALSLALSSVRST--ETHVERVLSLQFRDQSLKR-----SLVHLHFPTWPELGLPDSPSNLLRFIQEVHAhylhqRPLHTPIIVHCSSGVGRTGAFALLY . | . . . | . ..... . |.... |.. | . ...... |. .. ..||.||||.||||| .. .. | GkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk-----kkkekPivvhcsaGvGrtatlvGid AAVQEVEAGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCY . . . | |. ..||..|. | . .| .| | . yatirirensei-evldivrelramrlkavqshlqflfll |
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Phosphatase | PTPN23.AA | Subfamily.N_Nematode_6.PD | 1215-1449 | 29 | 2e-34 | 110.3 | In-house | 22-248 (253) | Show / Hide |
Range on Protein: 1215-1449 Range on HMM: 22-248/253 Sequence Identity: 29% (66 aa) RCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEgLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHG .. .||.... .| |..| .| || |. |. .|. |. ||||| || .|| |. . | ||||. | |.| |.|.. . |. .. . | lkfkdrnrytniqCcdagrlkladdedfyihanlvk-istkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarkit ALSLALS-SVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHylhqrplHTPIIVHCSSGVGRTGAFALLYAAVQEVE . . .. . . |.| .. . . |.|. ||. |.||| ||... |. .. ||.||||.||||||..||. ... . . . ... klctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkd-------kkPivvhCsaGvGrtGtlaliliilealr AGNGIpELPQLVRRMRQQRKHMLQEKLHLRFCYEAV .|. ..|..| . .| .. . . | lpdfq-gvkdllvklreerfravqtevqylyalrcv |
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Phosphatase | PTPN23.AA | Subfamily.N20.PD | 1220-1450 | 33 | 2.6e-34 | 110.0 | In-house | 29-253 (257) | Show / Hide |
Range on Protein: 1220-1450 Range on HMM: 29-253/257 Sequence Identity: 33% (77 aa) KNRHQDVMPYDSNRVVLRSGKdDYINASCVEGLSPYC-PPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSL |||..|..|||| || | | |||||| . . .||| || | ||| || |.. || |. | | |. .|.| .|. . . knryrdilpydstrvplgksk-dyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkkplelkhfrv ALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQevhahYLHQRPLHTPIIVHCSSGVGRTGAFALLYAaVQEVEAGNGI | . . . |.. . . .|. .|.| ||. | | | .....|. | .. | |..||||.|.||||| . | | flenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyir-----yarkshltgpmvvhcsagigrtgvflcvdv-vfcaivkncs PELPQLVRRMRQQRKHMLQEKLHLRFCYEAVV .. ..| .||.|| |.| | . .|||. |. fnimdivaqmreqrsgmvqtkeqyhfcydivl |
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Phosphatase | PTPN23.AA | Subfamily.R_Nematode_3.PD | 1217-1452 | 26 | 9.8e-34 | 108.0 | In-house | 23-265 (267) | Show / Hide |
Range on Protein: 1217-1452 Range on HMM: 23-265/267 Sequence Identity: 26% (65 aa) YSLKNRHQDVMPYDSNRVVLRS----GKDDYINASCVEGLSPYCppLVATQAPL--------PGTAADFWLMVHEQKVSVIVMLVSEAE---MEKQKVAR .. ..|...|. . ..|||| |||.|.|. || . . |. ||.|. | || |....|| ..||| . | |..| .. kvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpnglk--lIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcse YFPTERGQPMVHGALSLAL-SSVRSTE-THVERVLSLQFRdQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHylhqrplHTPIIVHCSSGVGRT |.|.. .. . . .|. . . .. ..| | ..| . . ||.. |.||. |..| ..| |. |.. ||..|||| |..|. Yypekvdgelkfegvsvkctdikkelsedvekrtlvvtfe-kkkeftvthllykgWkelnapeepkealelikfveks-------ktpvvVHCsdGisRs GAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRH ...| ..| . .| .| .|. .|.||.. .|..| | |... atlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkl |
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Phosphatase | PTPN23.AA | Subfamily.R_Nematode_2.PD | 1220-1444 | 32 | 2.4e-33 | 106.6 | In-house | 32-251 (261) | Show / Hide |
Range on Protein: 1220-1444 Range on HMM: 32-251/261 Sequence Identity: 32% (73 aa) KNRHQDVMPYDSNRV-VLRSGKDDYINASCVEGlSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSL |.|..|| .. .| |. || | | |. . .|||.|| | ||| || .|| |||| | ||.| ..|||.| .| .. | .|. khRypdvPCkpetavevivdgkrvpihanwvpt-agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgrfsi ALSSVRSTETHVERVLSLQFRDQSL---KRSLVHLHFPTWPELGLPDSPsnllrfiQEVHAHYLHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAG . |... .. . .|. |.. |.. |. . ||. |.|.| .|... . ||.||||.|.|||.|| .|||| . | || ktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPksh-------aelfeLlelvkksekPivvhCsaGiGRtmafigteylarevead NGIpELPQLVRRMRQQRKHMLQEKLHLRF .... .|..| . .|.. | . pti-eltealkelrehRwkgiqtesqlyw |
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Phosphatase | PTPN23.AA | PTPc_motif | 1346-1451 | 30 | 5.2e-32 | 113.57 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 1346-1451 Range on HMM: 1-92/92 Sequence Identity: 30% (34 aa) SLVHLHFPTWPEL-----GLPDSPSNLLRFIQEVHAHYLHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKL .. |.|...||. |.|. ...|.||..|.. ||.|||| |.|||| |.... ..| . |.|..||.|| .| | . TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK----------PIVVHCSAGCGRTGTFCAIDMMMQQ-------VDIFQTVKEMRKQRPGMVQTEE HLRFCYEAVVR .|||... QYIFCYRCILE |
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Phosphatase | PTPN23.AA | Subfamily.N_Nematode_egg.PD | 1212-1453 | 26 | 2.7e-20 | 64.0 | In-house | 21-256 (257) | Show / Hide |
Range on Protein: 1212-1453 Range on HMM: 21-256/257 Sequence Identity: 26% (66 aa) AIARCYSLKNRHQDVMPYDSNRVVL--RSG--KDDYINASCVEGlSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMekQKVARYFPTER |.. | | | . | .| || | | | ||.| | |.| | .. .|||| | ||| ||...|| |||| | | .. |.| aasdnylekarskrvhckessrvklelrrGqylddfihanrvkG-kpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyywpkae GQPMVH--GALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIqevhahylhqRPLHTPIIVHCSSGVGRTGAFALL ...| |.| . | | . || |. . . . |. ||..|| . | | .|..|.. || ..... . seslvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwqgdvnylsdvysplrvlrkl----------rnlskpvvvqdilGvskaatlvai YAAVQEVEAGNGIP-ELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV |. .. | . . | .|..|. .. | || |.... eiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlffi |
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Phosphatase | PTPN23.AA | Subfamily.N_Fungi_PTP1.PD | 1219-1305 | 34 | 4.9e-17 | 53.0 | In-house | 47-150 (343) | Show / Hide |
Range on Protein: 1219-1305 Range on HMM: 47-150/343 Sequence Identity: 34% (35 aa) LKNRHQDVMPYDSNRVVLR------------SGKDDYINASCVEGL--S-PYCPPL--VATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVAR |||.....||. .|| |. .|||||. .. | | .||||||| | ||. .. . ||||..| |. |.. .|. ||. aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr YFPT . YWqe |
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Phosphatase | PTPN23.AA | Subfamily.N_Nematode_eak.PD | 1220-1362 | 28 | 8.1e-13 | 39.4 | In-house | 29-171 (281) | Show / Hide |
Range on Protein: 1220-1362 Range on HMM: 29-171/281 Sequence Identity: 28% (41 aa) KNRHQDVMPYDSNRVVLRSG---KDDYINASCVEgLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERgQPMVHGAL .|| ...|.| . | | | .| ||||| .| .| . | .. || || ||| ||.|. . |...| .||| . . . .| | rnrvvkivpqdrylvrltssqlnrdGyinaslae-fsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdkt-evlkyGil SLALSSVRSTETHV-ERVLSLQFRDQslKRSLVHLHFPTWPELGLPD . . . . | | |. .. . | .. | |. || dverkeyavkrniletrllilrkGne--thrvlhykvfGwtettlpk |
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Phosphatase | PTPN23.AA | Subfamily.N_Fungi_PTP1.PD | 1347-1449 | 27 | 5.5e-10 | 29.8 | In-house | 215-338 (343) | Show / Hide |
Range on Protein: 1347-1449 Range on HMM: 215-338/343 Sequence Identity: 27% (30 aa) LVHLHFPTWPELGLPDSPSNLLRFIQ-------EVHAHYLHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQE-------------VEAGNGIP-ELPQLV . .|.. |..|.| | ..|. .. . |. . .||.||||.|||||| . | ..... . . . ..| ..|.|| | |. vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiiv RRMRQQRKHMLQEKLHLRFCYEAV . |.|||. nelrkqrismvqnldqfifiYeal |
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Phosphatase | PTPN23.AA | Family.DSP.PD | 1324-1408 | 17 | 1.6e-06 | 18.8 | In-house | 127-208 (387) | Show / Hide |
Range on Protein: 1324-1408 Range on HMM: 127-208/387 Sequence Identity: 17% (15 aa) RSTETHVERVLSLQ-FRDQSLK-RSLVhlhfptWPELGLPDS-PSNLLRFIQEVHAhYLHQ--RPlHTPIIVHCSSGVGRTGAFALLYAA | | ....|. ..| | . .....|. ...| ...... .... .. . . ||| |.||.| | wlkelgvtkivnltddkpqftkelgik------ylripidDhnapplenlfekaid-fieegnds-kgvVlVHCkaGkgRsgtliiaYlm |
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Phosphatase | PTPN23.AA | Subfamily.N_Nematode_eak.PD | 1374-1453 | 22 | 2.7e-06 | 18.0 | In-house | 201-280 (281) | Show / Hide |
Range on Protein: 1374-1453 Range on HMM: 201-280/281 Sequence Identity: 22% (18 aa) VHAHYLHQRPLHTPIIvHCSSGVGRTGAFALLYAAVQEVEAG-NGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHV . .| | | ..||| .. | |.|.| .. .. ... . . .|. .....|.| .|. | ||.|. .. tlkkyihtppsfapii-qsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl |