Gene PTPN5
PTPN5
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTPN5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PTPN5.AA | PTPc | 299-557 | 33 | 3e-115 | 390.1 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 299-557 Range on HMM: 1-308/308 Sequence Identity: 33% (103 aa) LLQAEFFEIPMNFVDP-----------KEYDIPGLV--RKNRYK-TILPNPHSRVCLTSPDPDD---PLSSYINANYIRGYGGEEKVYIATQGPIVSTVA ...|| ......... .. . | . .||||| |....|.||.|..|. .. . | |||||||.|| ...| ||.|||| .|.. GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-WRPKRYICTQGPLPHTIE DFWRMVWQEHTPIIVMITNIEE---------MNEKCTEYWPEEQVAYDGVEITVQKVIHTE-DYRLRLISLKSGT----------EERGLKHYWFTSWPD ||||||||....||||..|..| ||| |||.| . |.. ..| ... ... || .| .... .. |.| ..||..|.||| DFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDEPMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPD QKTPDRAPPLLHLVREVEEAAQQEGPH----------------CAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQY ...|. . ..|...|.|.. ...... .||.||||||.||||.|.| .|.|||... |||... ...|. | ||.|| ||| HGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQY QFVHHVMSLYEK .|..... | | IFCYRCILEYIK |
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| Phosphatase | PTPN5.AA | Subfamily.N5_RR.PD | 300-557 | 52 | 1.2e-124 | 406.2 | In-house | 2-265 (265) | Show / Hide |
Range on Protein: 300-557 Range on HMM: 2-265/265 Sequence Identity: 52% (140 aa) LQAEFFEIPMNFvDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMIT |..||.|.|.|| ...|....| .||||||||||..|||.|.| ...|..|||||||||.||..|.|.|.|||||...|.||||||..||....|||.| lekeflelPlnf-sqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmlt NIEEMNE-KCTEYWPEEQVA-----YDGVEITVQKVIHTEDYRLRLISLKSGTE-ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPI ...|.|. ||..|.|... . |..|||.|.......||..| ..||. .. || .||||.|.|||.|.||.. .||.||.||||....| ..||. klkeanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaPv IVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEK .|||||||||||||||.||...|||.|.|||.||..|.||.|||||.||.|||...|....||.| vvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk |
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| Phosphatase | PTPN5.AA | Y_phosphatase | 322-554 | 40 | 1.1e-105 | 362.16 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 322-554 Range on HMM: 1-243/243 Sequence Identity: 40% (100 aa) LVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNE--K-CTEYWPE---- .||||| |... |.||.|... |.|. | |||||||.|.....| ||.|||| .|..||||||||.....|||..|..||. | | .|||. NKEKNRYKDIPCYDHTRVKLQPI-PGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEG EQVAYDGVEITVQKVIHTEDYRLRLISLKSGT----EERGLKHYWFTSWPDQKTPDR-APPLLHLVREVEEAAQQEGPHCA--PIIVHCSAGIGRTGCFI . . |.. ..|.... |..|| .| ... . |.| ..||..|.|||...|. . ..| ..|.|... . |. ||.||||||.||||.|. QPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP--NPDHGCPPIVVHCSAGCGRTGTFC ATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSL | .|.|||...||.|||... ...|. | ||.||.|||.|..... AIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | PTPN5.AA | Subfamily.RB.PD | 324-552 | 44 | 2.7e-76 | 247.6 | In-house | 28-256 (261) | Show / Hide |
Range on Protein: 324-552 Range on HMM: 28-256/261 Sequence Identity: 44% (99 aa) RKNRYKTILPNPHSRVCLTSPDpDDPLSSYINANYIRGYGGeEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNI-EEMNEKCTEYWPEEQ--VAYD |||.. ||| |||| |.. . |.. . ||||||| || .. |||||||. .|| |||||||.... ||||.|.. |. ||| ||||...|.| .. aknrftnilpydhsrvkLaalk-desdtdyinanyipgyns-preyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYWPadeepvlyG GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEgPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEG .|... ..... .| .....|.|.| ...| |||||| .|... .||..||.|.||.... .. .||.||||||.|||| ||||..... .||.. . dikvtllaekeldewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekk-askkPivvHCsaGvGRtGtfialdrllqaieend VVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM ..||..| ..|| .|| |.|... yvdvfgvvaelReeRnllvqtekqyifihecl |
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| Phosphatase | PTPN5.AA | Subfamily.N_Choan_2.PD | 313-555 | 36 | 7.2e-76 | 246.1 | In-house | 9-264 (266) | Show / Hide |
Range on Protein: 313-555 Range on HMM: 9-264/266 Sequence Identity: 36% (95 aa) DPKEYDIPGLVRK---NRYKTILPNPHSRVCLtSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMN-EKC ..| .|| .|. |||. |||.|..||.| .. .|. ..||||||.||. ||.| |||..|| .|. .||||.|.|... |||.|..|| . .|| evseeaiPeyarnkrlnRyndiLPsPatRvrl-eeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkC TEYWPEEQ---VAY--DGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAP------PLLHLVREVEEAAQQEGPHCaPIIVHCS |||.|. |.. ....... ..| |.|. . |. . |.| |.|.|...|||. | .. ||...|.| . .. |..||||| erYWpaepkekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkae-PllvHcs AGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY |.||||..||. |... | ... ||.|. .||.|| ..|. |||........ | aGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavvey |
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| Phosphatase | PTPN5.AA | Subfamily.R_Anemone_2.PD | 324-553 | 43 | 1.3e-75 | 245.6 | In-house | 29-258 (262) | Show / Hide |
Range on Protein: 324-553 Range on HMM: 29-258/262 Sequence Identity: 43% (100 aa) RKNRYKTILPNPHSRVCLTsPDPDDPLSSYINANYIRGYGgEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEM-NEKCTEYWPEEQ-VAYDG .|||| ||. ..|| |. . ... | ||||||| || ..| |||||.|. |. |||||||. .. .|||.|..|| |. |||... .|. aknryanilaydktrvklq-mlegeegsdyinanyidGyr-rkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygk VEITVQKVIHTEDYRLRLISLKSG--TEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHcaPIIVHCSAGIGRTGCFIATSICCQQLRQE . ..... ....|| || ...| ||| .. . .|||||. .|. . ||.|||.||.| |..| .||.||||||.|||| ||| .| .....|.. lvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgag--pivvhcsaGvGrtGvfiavdillerikae GVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMS ||...| |||. | |.|| .||.|...|. alvdvfqtvkqlreqrnlmvqtkdqyefiydvll |
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| Phosphatase | PTPN5.AA | Subfamily.R_Anemone_1.PD | 324-552 | 41 | 4.6e-71 | 230.7 | In-house | 27-253 (258) | Show / Hide |
Range on Protein: 324-552 Range on HMM: 27-253/258 Sequence Identity: 41% (97 aa) RKNRYKTILPNPHSRVCLTsPDPDDPLSSYINANYIRGYGGEeKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEE-MNEKCTEYWPEEQVAYDGV .||||. |.. |||| |. .|. | |||| |.|.. . . .||||.|. .||.|||||||||.. .|||.||..| ..||..|||... .|. . kknryadivaldhsRvvLe-klsndeesdYinasylrasdkt-rafiatqapleetvedFWrmvwqekigviVmLtnliegekkkchqYwPdstekygel EITVQKVIHTEDYRLRLISLKS--GTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAaQQEGphCAPIIVHCSAGIGRTGCFIATSICCQQLRQEG .....| . || .| . |.. |||| . .| ||.|||. |. | .|.|.|.|.. ...| .|..||||||.|||| |.. . .|...| rvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks-slag--arpvvvhCsaGvgRtGaflvidamleqakkek VVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM |||| .. ..|.|| |.|| ||| |.|... vvDifnyvkairedrphmvqtkeqyvfihlav |
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| Phosphatase | PTPN5.AA | Subfamily.R_Sponge_2.PD | 323-553 | 39 | 9.5e-71 | 229.6 | In-house | 26-258 (262) | Show / Hide |
Range on Protein: 323-553 Range on HMM: 26-258/262 Sequence Identity: 39% (93 aa) VRKNRYKTILPNPHSRVCLTSpdPDDPLSSYINANYIRGYGgEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEM-NEKCTEYWPEE---QVA | |||.| ||| .||| |.. .. . | ||||... || ..| |||||||. .||.||||||| ....|||.||.|| .|||..||||. .| vgKnRfkeilpydmsRvrLrt--dgskdsDYinAsfvdgyk-rrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPekvdeeve YDGVEITVQKVIHTEDYRLRLISLKS---GTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHcaPIIVHCSAGIGRTGCFIATSICCQQ | ...|... ...|| .| . |.. .|. .... |..||....|. | .||.|...|..| ...|.. .|.|.||.|.|||| ||| . .. ygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnk--aitvvCsdgvgrtGtfialdsvler LRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMS |..|...|. .. .|| | |..|. .||.|.|.... lkaeeeidvfevlktlrtkriglvqdaaqYvfihdall |
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| Phosphatase | PTPN5.AA | Subfamily.RK.PD | 323-552 | 35 | 3.5e-67 | 217.6 | In-house | 30-262 (267) | Show / Hide |
Range on Protein: 323-552 Range on HMM: 30-262/267 Sequence Identity: 35% (84 aa) VRKNRYKTILPNPHSRVCLTSPDPDdpLSSYINANYIRGYGgEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNI--EEMNEKCTEYWPEEQVA-Y .|||.. ||. .|.| |.| | | | ||||..| .| . .|.||||. .||.||||.|..|.. |||.|.. |... ||..||||. |. reknrsmdilaydrslvflisvdgd--ssdyinaalidsyk-rpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyWPedtevry DGVEITVQKVIHTEDYRLRLISLKS----GTEERGLKHYWFTSWPDQ-KTPDRAPPLLHLVREVEEAAQQegPHCAPIIVHCSAGIGRTGCFIATSICCQ ..... .. .|. |. ... | | .... |..||. ..|. . ||.|.|.|.. .. . .|.|||.|| ||.|.||| .| .. gdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee--eeeGrivvhClaGaGrsGtfiaidivle QLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM ...|||||. .. .||. . |..| |||.||. |. mieregvvdvfnavktlrnrkvnmveteeqykfvydvi |
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| Phosphatase | PTPN5.AA | Subfamily.R_Ecdysozoa.PD | 325-553 | 37 | 7.9e-67 | 216.5 | In-house | 30-265 (269) | Show / Hide |
Range on Protein: 325-553 Range on HMM: 30-265/269 Sequence Identity: 37% (87 aa) KNRYKTILPNPHSRVCLTSPDpDDPLSSYINANYIRGYGgEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWP-EEQVAYDGVE ||||. | . . || |. . |.||||..|.|| |.| .|| |.|. .|. |||||... . .|||..|..|.|.||.||| |..| |. . . knryedikafDktrvkLkkin-gkedsdyinasfikgyk-ekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknrkcakyWpiedevqygdil ITVQKVIHTEDYRLRLISLKSGT-----EERGLKHYWFTSWP-DQKTPDRAPPLLHLVREVEEAAQQE--GPHCAPIIVHCSAGIGRTGCFIATSICCQQ .. . ...|| | ... ..| . | .|.|. |.| |. | ||.|...|.| ....||.|||||| ||.| |.| .. |||..| | vklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgrsgifvaldlllqq LRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMS ||..|...||..| ..| |||.|... . lkaedkvdifetvkkLrsqrnllvqsleqyvflyrala |
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| Phosphatase | PTPN5.AA | Subfamily.N12.PD | 323-552 | 37 | 1.5e-66 | 215.5 | In-house | 33-265 (270) | Show / Hide |
Range on Protein: 323-552 Range on HMM: 33-265/270 Sequence Identity: 37% (89 aa) VRKNRYKTILPNPHSRVCLTSPDPDDpLSSYINANYIRGYGGeEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMN-EKCTEYWPEE---QVA |.||||| ||| .||| |. . .. |.|||||.|.| | .. |||.|||. .|. |||||.|. .. |.||. .. |.. || ||||| .. vkknrykDilPydksrvelskieeee-gsdyinanfikgveg-kleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpeegeeele YDGVEITVQKV-IHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQqegPHCAPIIVHCSAGIGRTGCFIATSICCQQLR .. .|.|... ..|. .| . .. |.| .. . .|.|||. .| .| .||.|...|.| . . ||..||||||.|||| || . ..|. fgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqe---sedaPlvvhCsaGvGrtGtiiaidyvrellk QEGV---VDILKTTCQLRQDRGGMIQTCEQYQFVHHVM .| . .|. . .||..| ..|| |||..|.. . aekipeeldvfdlvlelrkqraalvqtkeqyelvykav |
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| Phosphatase | PTPN5.AA | Subfamily.N9.PD | 320-552 | 39 | 1.2e-65 | 212.9 | In-house | 24-270 (275) | Show / Hide |
Range on Protein: 320-552 Range on HMM: 24-270/275 Sequence Identity: 39% (99 aa) PGLVRKNRYKTILPNPHSRVCLTSPDpDDPLSSYINANYIRGYGgEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMN-EKCTEYWP-EEQV .. ..||||. .| ..|| |.. | .|. | |||||.. || ..| .||||||. || |||||||.... .|||.| ..|.. ||..||| ||. ranleknrytdvlcydetrvklakld-edeasdyinanfvdGyk-qkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywpleees AYDGVEITVQK--VIHTEDYRLRLISLK--SGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAA----------QQEGPHCAPIIVHCSAGIGRT . . ....|.. | ..|||. | . .| |.| . |. |.|||| .|. | ||.....| |. .. .. ||.|||||||||| saefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGrt GCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM | ||. || ..|...|.||. .| .||. | .||| |||.| . . Gtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylav |
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| Phosphatase | PTPN5.AA | Subfamily.N6.PD | 324-555 | 41 | 1.4e-65 | 212.7 | In-house | 42-293 (295) | Show / Hide |
Range on Protein: 324-555 Range on HMM: 42-293/295 Sequence Identity: 41% (103 aa) RKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYI--------RGYGGE----EKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNI-EEMNEKCTE .||||| ||| |.|| |. .|. | | ||||||| .| | | ||||||.. .||.||||||||| . .|||.|. |.||. ||| eknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqensrvivmttkevergknkCar YWPEEQVAYDGVEITVQKVI--HTEDYRLRLISL---KSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEgPHCAPIIVHCSAGIGRTGC .|. . .|||... .|.|| || .|. .. .|.| . .| |..|||. .| . .|.....|.. ... . ||.||||||||||| || YWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeel-ekagpivvhcsaGiGrtGt FIATSICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY | ....|.|. .|| |. ..|. | |..|| .||.|| .... | fividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfy |
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| Phosphatase | PTPN5.AA | Subfamily.RA.PD | 323-553 | 39 | 4e-65 | 211.0 | In-house | 28-262 (266) | Show / Hide |
Range on Protein: 323-553 Range on HMM: 28-262/266 Sequence Identity: 39% (92 aa) VRKNRYKTILPNPHSRVCLTSPDpDDPLSSYINANYIRGYGgEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEM-NEKCTEYWPEE-QVAYD .|||. |||. .||| |. . . | |||| .| || | . .||.||| || |||||.|. .. |||.|...| .|||..|||.||.| . kkknrvvqilpydfsrvilsvke-GeeesdyinasfidGyr-ekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqywpdeGlvtyG GVEITVQKVIHTEDYRLRLISLK---SGT---EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHcaPIIVHCSAGIGRTGCFIATSICCQ ..|... .||| .| . .. | ..| .. . |||||. | . .|.|...|.. ||.. | ||.||||||.|||| ||. . .... eirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanh--pivvhcsaGvGrtGtfivldavle QLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMS |...|. .. .||. | |.|| |||.|...|. rvkaerkldvfeavkrlrlqrpqmvqtleqyefiykvll |
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| Phosphatase | PTPN5.AA | Subfamily.RG.PD | 324-553 | 35 | 1.5e-63 | 205.9 | In-house | 29-260 (264) | Show / Hide |
Range on Protein: 324-553 Range on HMM: 29-260/264 Sequence Identity: 35% (82 aa) RKNRYKTILPNPHSRVCLTsPDPDDPLSSYINANYIRGYGgEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEE-MNEKCTEYWPE--EQVAYD .|||. |.. .||| |. | |. . ||||.||.|| .| ||.||||. .|. |||||.|.... ||||.|...| ...... |||.| . .. . eknReinivaversRvkls-plpgkdgkDYinAsyidGyr-rskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrdedvyWPkkdeplele GVEITVQKVIHTEDYRLRLISLKSGTEERGLK----HYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQegpHCAPIIVHCSAGIGRTGCFIATSICCQQL ..|. . ....| .| ..||. ..... .| .|.|||...|. . . | |. | | .. . ||.||.||| ||.|.|| . |||..| alkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaanke---eaGPivvhdsaGvgragtyialdtllqql RQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMS |..... ..|. | |...| |||.|...... ekeeavnvyqvlklirakRpglvtteEqyvfiydall |
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| Phosphatase | PTPN5.AA | Subfamily.N_Choan_1.PD | 323-553 | 35 | 3.3e-61 | 198.2 | In-house | 27-258 (262) | Show / Hide |
Range on Protein: 323-553 Range on HMM: 27-258/262 Sequence Identity: 35% (82 aa) VRKNRYKTILPNPHSRVCLTsPDPDDPLSSYINANYIRGYGGEEKvYIATQGPIVSTVADFWRMVWQEHTPIIVMITN-IEEMNEKCTEYWPEEQ--VAY | ||||. | ..|| .| |. .. . |||||.. || ||.. |||||||. .....||.|||... .|||.|. ||. . |||||.|. . . vlknrysnivayDatrvkvt-pneenkntDyinanfvpgykgeke-yiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWPdenselkl DGVEITVQKVIHTEDYRLRLISL-KSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPhcAPIIVHCSAGIGRTGCFIATSICCQQLRQ | .. .. ... | | ..| ....|.| ... .|.|||. |. . ||. ..|..| ... ||...|||||.||||..|| ....... gdvtvkslseeekktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk--aplvihCsaGvGrtGtyialDrlvkavee EG-VVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMS ..|. . .||..| |.|| ||.||.... kaealdvkavvaelrkernlmvqtlvqyefvykavl |
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| Phosphatase | PTPN5.AA | Subfamily.N3.PD | 322-551 | 35 | 1.6e-56 | 182.6 | In-house | 26-256 (261) | Show / Hide |
Range on Protein: 322-551 Range on HMM: 26-256/261 Sequence Identity: 35% (84 aa) LVRKNRYKTILPNPHSRVCLTSPDPDdplssYINANYIR-GYGGEEKV--YIATQGPIVSTVADFWRMVWQEHTPIIVMITN-IEEMNEKCTEYWPE--E . ||||. ||| . || |.. . | ||||||. ... | |||||||. .|..|||.|||.... .|||.|. .|. || .|||| .. nlaknryrdilpydatrvklkesetd-----yinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqyWPeted QVAYDGVEITVQKVIHTEDYRLRLISLKSGT--EERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQegpHCAPIIVHCSAGIGRTGCFIATSICC . . .......| .|. | || . || . ||| . . ...|||.. || . .|..|..|... . . |..||||||||||| .|. .. . elefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsg---keePvvvhCsaGigrtGvlilletal QQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHH-V . .. | .|. ..|. |. ..|| .||.|| . . alieaaepvypldivrtmrdqramlvqtvsqykfvCeai |
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| Phosphatase | PTPN5.AA | Subfamily.N13.PD | 324-552 | 34 | 1.3e-55 | 180.0 | In-house | 28-254 (259) | Show / Hide |
Range on Protein: 324-552 Range on HMM: 28-254/259 Sequence Identity: 34% (82 aa) RKNRYKTILPNPHSRVCLTSPDPddplssYINANYIRGYGGEE-KVYIATQGPIVSTVADFWRMVWQEHTPIIVMITN-IEEMNEKCTEYWPEEQ----V .||||. .|| ..|| | . . ||||..|. ||. .|||.|||. ||.|||.|||. .. .|.|.|. |. . || ||||.. . dknryrnvlPydetrvklgdegg------yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerknkklk AYDGVEITVQKVIHTEDYRLRLISLKS--GTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQqegpHCAPIIVHCSAGIGRTGCFIATSICCQQ ... .|... || . ... .| . .| .| | . | |..||| ..| | .|...|.|| . .. . .||.|||||||||.| .|. . . vsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt----dagPivvhcsaGiGrsGvlitidvvlgl LRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM . .. .|. .. .||. | |..|| .|| ||.... ierdkefdvkeivrklreqrqgvvqtkdqyifvykai |
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| Phosphatase | PTPN5.AA | Subfamily.RC.PD | 300-555 | 31 | 1.4e-53 | 173.2 | In-house | 2-286 (288) | Show / Hide |
Range on Protein: 300-555 Range on HMM: 2-286/288 Sequence Identity: 31% (90 aa) LQAEFFEIPMNFV--DPKEYDIPGLVRKNRYKTILPNPHSRVCL---------------TSPD---PDDPLSSYINANYIRGYGgEEKVYIATQGPIVST |.||| ..| . |. . |||| .|| . || | | | . | |||| .| .| . ..|||.||| | leaefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsyk-kpekyiaaqGplket VADFWRMVWQEHTPIIVMITNIEEMN-EKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGT--EERGLKHYWFTSWPDQKTPDRAPPLLHLVR | |||||.... . .|||.|...| . |||.||| | . || ||. ... .. || || . |. . | . .. .|||....|. ||.|.. vddfwrmiferkvkvivmltelkeGdrekcaeyweeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliq EVEEAAQ-------QEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY |.. . . .|..|||..| .||| ||| . | | .||. . .||..| .|... |||.....|. . vvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet |
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| Phosphatase | PTPN5.AA | Subfamily.RN.PD | 321-551 | 37 | 1.3e-50 | 163.3 | In-house | 26-258 (264) | Show / Hide |
Range on Protein: 321-551 Range on HMM: 26-258/264 Sequence Identity: 37% (89 aa) GLVRKNRYKTILPNPHSRVCLTSPDPdDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEE-MNEKCTEYWPEEQV-A |.|||.|..|| |||| |.. . | |||| | . .|||||||. ||.||||.|||.. . .||..|..|| ..|..|||.| |. knvkknrskavlpydhsrvklkeeas-aeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsev YDGVEIT-VQKVIHTEDYRLRLISLKS--GTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQqeGpHCAPIIVHCSAGIGRTGCFIATSICCQQ |. | . | ..|| .| . || | | . . | |||.. .| | .||.. | |. . . | ..||.||||.| ||||..|. . ...| yhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyr--G-rscpivvhcsdGaGrtGvyilidlvler LRQ-EGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHV . .|| | ||..| |...| .|..|. . llkGvkeidiaatlehlrdqrpglvktkdqfefalta |
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| Phosphatase | PTPN5.AA | Subfamily.N14.PD | 322-553 | 32 | 4.8e-50 | 161.5 | In-house | 26-271 (275) | Show / Hide |
Range on Protein: 322-553 Range on HMM: 26-271/275 Sequence Identity: 32% (81 aa) LVRKNRYKTILPNPHSRVCLTSPDPDdpLSSYINANYIRG-YGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNI-EEMNEKCTEYWPEE---- ..|||.| .|| ..|| |.. . . |||| |. ||.|. ||..|||. || |||.|||.... .|||.|.. |. .||. .|.|.. naeknrfkdvlPyednrvelsptken--stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeksfkylPkleskk -QVAYDGVEITVQKVIHTEDYRLRLISLK--SGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPH-------CAPIIVHCSAGIGRTGC .| .. ..| . . ... . . . || ||| . | .| |||.. |. ..|. ..||. .. . |..||||||.|||| ktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtGv FIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMS | . . . | .. ..|| |. .||. | ..|| ||.||..|. lilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvli |
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| Phosphatase | PTPN5.AA | Subfamily.N23.PD | 334-551 | 33 | 7.8e-49 | 157.8 | In-house | 114-344 (350) | Show / Hide |
Range on Protein: 334-551 Range on HMM: 114-344/350 Sequence Identity: 33% (74 aa) NPHSRVCLT-SPDPDDpLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEM-NEKCTEYWPEEQ---VAYDGVEITVQK . ..||.| |..| . |||| |.. .||||||| ||.|||| |||......|||.|. .|. || .|||... . .......... hdpnrvklqqstqpgq-qddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslks VIHTEDYRLRLISLKSG--TEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAA------QQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQL-RQE ..| . | ..|. | ..| .|.|.. |. ||... |||.| . || |||.|||||.|||| |..| ..|...|.. lrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagn GVVDILKTTCQLRQDRGGMIQTCEQYQFVHHV .|||.| |.|. ...... .. giiniprvvrrlrqqRkymvqkkvilkklyea |
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| Phosphatase | PTPN5.AA | Subfamily.N1.PD | 319-549 | 30 | 9.8e-45 | 144.3 | In-house | 25-260 (268) | Show / Hide |
Range on Protein: 319-549
Range on HMM: 25-260/268
Sequence Identity: 30% (74 aa)
IPGLVRKNRYKTILPNPHSRVCLTSPDPddplsSYINANYIRgYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNI-EEMNEKCTEYWPEEQV
| .|||. . | |||. | . | ||||. . .. || ||||.. |. ||.|||.... ..|. .. |. . ||..|||.|.
lpenrglnryrdvspydhsrikleradv-----dyinaslve-leeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqeee
----AYDGVEITVQKVI--HTEDYRLRLISLKS--GTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEgPHCAPIIVHCSAGIGRTGCFIAT
.. ....|. . ... ...||. |. | | . |. .| ||| |. .|... .| |. .. .|...||||||||.| . .
eaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLs-sdvgpavihCsagigrsgtlslv
SICCQQLRQEGV---VDILKTTCQLRQDRGGMIQTCEQYQFVH
| .. ..| ||| | ..||. | |.||| .| .|
dtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsy
|
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| Phosphatase | PTPN5.AA | Subfamily.N_Nematode_4.PD | 324-552 | 31 | 7.1e-43 | 138.1 | In-house | 28-259 (264) | Show / Hide |
Range on Protein: 324-552 Range on HMM: 28-259/264 Sequence Identity: 31% (76 aa) RKNRYKTILPNPHSRVCLTSPDPDDplsSYINANYIRGYggEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITN-IEEMNEKCTEYWPEEQVA---Y ||||. || ..|| | ||| || |...| .. ||.||||. |..||| ||..| ....||. . ||| |||. |.||.. . dknryadilcidetrvvlknrdpdn---dyihaswmrmP--dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkf DGVEITVQKVIHT--ED---YRLRLISL----KSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEaAQQEgphcAPIIVHCSAGIGRTGCFIATS .||. . . | |.... .. .|. .||. .. |.|| .| | |...| . |. ..| ||.||||||.||| .. .. GkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk-kkke----kPivvhcsaGvGrtatlvGid ICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVM ...|. . ...|. .||. | . .|. |. |. |. yatirirenseievldivrelramrlkavqshlqflfllvvl |
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| Phosphatase | PTPN5.AA | Subfamily.N_Nematode_1.PD | 324-555 | 34 | 1.1e-42 | 137.4 | In-house | 28-263 (265) | Show / Hide |
Range on Protein: 324-555 Range on HMM: 28-263/265 Sequence Identity: 34% (84 aa) RKNRYKTILPNPHSRVCLTSP-DPddplSSYINANYIrGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEM-NEKCTEYWPEEQ---VA ||||| . ..|| |... | | || |||. | . | .| .|.|. .|.|||| || ||. |||. .. |. .||.||.| .. . .. dknrykdvgcldknrvklaeeplp----sdyihanyv-gtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegekle YD--GVEITVQ-----KVIHTEDY--RLRLISLK-SGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAqqegphcAPIIVHCSAGIGRTGCFIA | .|||. | ..... . .... .|...| ..|| .| |||. | |.|..|.. .||.||||||||||| .| . fkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgsk-------gPivvhCsaGiGrtGtiva TSICCQQLRQE-GVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY ...| .. . |. | ..|..| ||| || |||.|. | ieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllny |
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| Phosphatase | PTPN5.AA | Subfamily.N20.PD | 320-551 | 35 | 2.8e-42 | 136.3 | In-house | 24-251 (257) | Show / Hide |
Range on Protein: 320-551 Range on HMM: 24-251/257 Sequence Identity: 35% (85 aa) PGLVRKNRYKTILPNPHSRVCLTSPDpdDplssYINANYIRG-YGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMIT-NIEEMNEKCTEYWPEEQ- | ||||. ||| .|| | | ||||.||| ||| .|||||||..||. |||.|| .. . .| ||| .|| ||||| psnreknryrdilpydstrvplgksk--d----yinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislk --VAYDGVEITVQK--VIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAqqegpHCAPIIVHCSAGIGRTGCFIATSIC . . . ... ... |. . || . .|. || |||. || | ... .| .. |..||||||||||| |.. . kplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarksh-----ltgpmvvhcsagigrtgvflcvdvv CQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHV . .. ..|. .|.|..| ||.|| |||.|.. . fcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydi |
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| Phosphatase | PTPN5.AA | Subfamily.R_Nematode_2.PD | 325-551 | 31 | 4.9e-42 | 135.2 | In-house | 32-255 (261) | Show / Hide |
Range on Protein: 325-551 Range on HMM: 32-255/261 Sequence Identity: 31% (72 aa) KNRYKTILPNPHSRVCLTSPDPDDPlssyINANYIRGyGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITN-IEEMNEKCTEYWPEEQ---VAYD |.||... .|...| ... | | ||.. |..| .||||||. |. ||| || ||. |||... .|. .|||.||.| |. . . khRypdvPCkpetavevivdgkrvp----ihanwvpt-agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlg GVEIT--VQKVIHTEDYRLRLISLKSGTE---ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQqegphcaPIIVHCSAGIGRTGCFIATSICCQQ ..|. .. | ... | . . .| | ..|| ...|||. .|. | |. | .. .||.||||||||||. ||.| ... .. . rfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek-------PivvhCsaGiGRtmafigteylare LRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHV . .. .||. | ||| .|. ... . veadptieltealkelrehRwkgiqtesqlywltlg |
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| Phosphatase | PTPN5.AA | PTPc_motif | 450-554 | 36 | 2.7e-40 | 141.1 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 450-554 Range on HMM: 1-92/92 Sequence Identity: 36% (40 aa) GLKHYWFTSWPDQ-----KTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQ ..||..|.|||. ..|. ..|...|.|.. ||.||||||.||||.|.| ....|| |||..| ...|. | ||.||.|| TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK----------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQ YQFVHHVMSL |.|..... YIFCYRCILE |
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| Phosphatase | PTPN5.AA | Subfamily.N_Nematode_5.PD | 324-555 | 27 | 2e-37 | 120.0 | In-house | 27-256 (258) | Show / Hide |
Range on Protein: 324-555 Range on HMM: 27-256/258 Sequence Identity: 27% (66 aa) RKNRYKTILPNPHSRVcltspDPDD-PlSSYINANYIRGYGGEEkVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVA---Y |||.| . . ..|| . | . .|||||..|. |. .| || | ..|..|||||| ||. .|.... ||..|. ....|.|. . .. kknrskdvkilDetrV-----kltded-dsYinaskiklddlek-kliltQlPlpdteedFWrmvyqekitsvvllvedeelketavsffpletgdylnl DGVEITVQKVIHTE----DYRLRLISLKSGTEeRGLKHYWFTSWPDQKTPDRAPPLLHlvREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQ .. |...|| . | | . ... . . . .|.| .| |...| ||. ... |..|. .... . ||..|....|.||.| |...|. ..|| gkmfinnrkvevkedekkeytvevlpegcses-vfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsdlGlgRagtflllsvaieq LRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY .. ..| .. ..|. | |.... || .|. .. | lnngkepnideilkkirsqRpgavesliqyasvyaavldy |
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| Phosphatase | PTPN5.AA | Subfamily.R_Nematode_3.PD | 351-550 | 27 | 3.8e-36 | 116.0 | In-house | 51-260 (267) | Show / Hide |
Range on Protein: 351-550 Range on HMM: 51-260/267 Sequence Identity: 27% (59 aa) SSYINANYIRGYGGEEkvYIATQGPI--------VSTVADFWRMVWQEHTPIIVMITNIEE----MNEKCTEYWPEE---QVAYDGVEI-TVQKVIHTE- . .|.||.. .| . | ||.| ||. || |. ||.. ..||. .. | .||| ||.||. ...||.. .... ... | ddfihAnvvecpnglk--lIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYypekvdgelkfegvsvkctdikkelse DYRLRLI--SLKsGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQqegphcaPIIVHCSAGIGRTGCFIATSICCQQ-LRQEGVVDILKTTCQ | . ... .| .|.....|... .|. . ..|.|.. ||. . |..||||.||.|.... |. . .| ....| .|.|. ..|| dvekrtlvvtfe-kkkeftvthllykgWkelnapeepkealelikfvekskt-------pvvVHCsdGisRsatlaaielgyqliikskgkldllslike LRQDRGGMIQTCEQYQFVHH . | | ||| ... || lrkqRagaiqtelelafvil |
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| Phosphatase | PTPN5.AA | Subfamily.N_Nematode_6.PD | 324-551 | 30 | 9.2e-34 | 108.2 | In-house | 26-247 (253) | Show / Hide |
Range on Protein: 324-551 Range on HMM: 26-247/253 Sequence Identity: 30% (68 aa) RKNRYKTILPNPHSRVCLTspdpDDPlSSYINANYIRGYgGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITN-IEEMNEKCTEYWPEE--QVAYD .|||. | .|. |. ||. || ||... ... .| ||.|. .|. .||.|. . |||. . .|. .||..|| ... . . drnrytniqCcdagrlkla----dde-dfyihanlvkis-tkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarki GVEITVQKVIHTEDYRLRLIS----LKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQqegphcaPIIVHCSAGIGRTGCFIATSICCQQL || |. ... .. | |.| || .||. . .||| || |.|. | . .||.||||||.|||| .. | . ||. .. tklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk-------PivvhCsaGvGrtGtlaliliileal RQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHV . .||..| .|| || .... rlpdfqgvkdllvklreerfravqtevqylyalrc |
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| Phosphatase | PTPN5.AA | Subfamily.N_Nematode_egg.PD | 325-555 | 27 | 6.9e-29 | 92.2 | In-house | 29-255 (257) | Show / Hide |
Range on Protein: 325-555 Range on HMM: 29-255/257 Sequence Identity: 27% (66 aa) KNRYKTILPNPHSRVCLTSPDPdDPLSSYINANYIRGYGgEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMnEKCTEYWPE---EQVAY-- | | | . . ||| | . | .| ||...| .| .| |. || ||||||.||. . |||.| | |.| ||| | . . karskrvhckessrvklelrrG-qylddfihanrvkGkp-llnefilaqaplkntvedfwrmvfqekvqyivmltsakes-erceyywpkaeseslvtvp DGVEITVQKVIHTEDYRLRLISLKS---GTEERGLKHyWftSWPDQKTPDRAPPLlHLVREVEEAAQqegphcaPIIVHCSAGIGRTGCFIATSIC-CQQ ...|. || . | .|. || ||. |.| | . ... | || ...| . .... |..|.. |. ......| | .. GslrienlkvdskadplfrvtklklvGgddeelfleh-w--qgdvnylsdvyspl-rvlrklrnlsk-------pvvvqdilGvskaatlvaieiallsl LRQEGVVD-ILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY || . .|.. ||. | ... .| ||. .. . lrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlff |
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| Phosphatase | PTPN5.AA | Subfamily.N_Fungi_PTP1.PD | 323-427 | 37 | 8e-25 | 78.7 | In-house | 46-161 (343) | Show / Hide |
Range on Protein: 323-427 Range on HMM: 46-161/343 Sequence Identity: 37% (44 aa) VRKNRYKTILPNPHSRVCLT-SPDPDDP------LSSYINANYIRGY----GGEEKV-YIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMN-EKCT ||||| ||| |||| | |. . | . ||||||.. . . |||||.|. ||| ||.... . . ..|...|. |.| ||| .| faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy EYWPEEQvaYDGVEITVQ |.| . ||.. . .. rYWqegs--ydditvkla |
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| Phosphatase | PTPN5.AA | Subfamily.N_Nematode_eak.PD | 323-466 | 28 | 3.9e-17 | 53.7 | In-house | 27-171 (281) | Show / Hide |
Range on Protein: 323-466 Range on HMM: 27-171/281 Sequence Identity: 28% (41 aa) VRKNRYKTILPNPHSRVCLTSPDPDdPlSSYINANYIrGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMI-TNIEEMNEKCTEYWPE--EQVAY |..|| |.|. . | ||| . . |||| . . . || | . . | ||.|| ....| ||.. ..|||| |.|. |.. | vnrnrvvkivpqdrylvrltssqln-r-dGyinasla-efsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevlky DGVEITVQKV-IHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPD .... .. .. . .. ||. |. | | ..|| . | . ..| GildverkeyavkrniletrllilrkGnethrvlhykvfGwtettlpk |
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| Phosphatase | PTPN5.AA | Subfamily.N_Fungi_PTP1.PD | 481-555 | 27 | 2.7e-10 | 31.0 | In-house | 252-341 (343) | Show / Hide |
Range on Protein: 481-555 Range on HMM: 252-341/343 Sequence Identity: 27% (24 aa) AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQ------QLRQE--------GVVD-ILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY . . .||.||||||.|||| ... . .|..| . | | . .||..| |.|. .|. |... . | eshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfy |
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| Phosphatase | PTPN5.AA | Family.DSP.PD | 433-561 | 18 | 3.5e-09 | 27.7 | In-house | 148-250 (387) | Show / Hide |
Range on Protein: 433-561 Range on HMM: 148-250/387 Sequence Identity: 18% (23 aa) EdyrlrlislksgteERGLKHYWFtSWPDQKTPDRAPpllHLVREVEeAAQQ-EGpHCAPIIVHCSAGIGRTGCfiatSICCQQLRQEGVVDIlKTTCQL . | | |.. . ...| .|. . .... .. .. . . . ||| ||.||.| |.. . .||. ...|. k--------------elgikylri-pidDhnapplen---lfekaid-fieegnd-skgvVlVHCkaGkgRsgt----liiaYlmksegltle-ealdwv RQDRGGMIQTCEQyqFVHHVMSLYEKQLSH | |.|. .. |.. .. |....|. rskRpgvitpnqg--flkqlkdlekeklkv |
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| Phosphatase | PTPN5.AA | Subfamily.DSP23.PD | 464-549 | 30 | 6.3e-09 | 27.2 | In-house | 41-121 (128) | Show / Hide |
Range on Protein: 464-549 Range on HMM: 41-121/128 Sequence Identity: 30% (26 aa) TPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIAtsicCQQLRQEGVVdILKTTCQLRQDRGGMIQTCEQYQFVH || || |. | .. . .. . .. ||| |.|||| ..| | ...||. .. ..|. | | |.| || . |. ipdfcPPaleqvarlvriveeaekkeeavgvhcalGlGrtGtlla----cylvkeegla-addaiaevrkrrkGsietveqekavk |
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| Phosphatase | PTPN5.AA | Subfamily.PTPDC1.PD | 450-552 | 32 | 6.7e-09 | 26.7 | In-house | 134-224 (229) | Show / Hide |
Range on Protein: 450-552
Range on HMM: 134-224/229
Sequence Identity: 32% (32 aa)
GLKHYWFtSWPDQKTPDRaPPLLHLVREVEEAAqQEGphcaPIIVHCSAGIGRTGCFIATSICC-QQLRQEGVVDilkttcQLRQDRGGMIQTCEQYQFV
|. .| | ...| ... .| .|. |. | .|| | ||| || |||| ||. . ..| | .. ..|. |||| || ..|..
giyfynf-glkDygvasl-eriLdivkvvdfal-eeg----kiavHCHAGlGRtGvliacylvyakrltaeeaik------lvrskrpksiqtreqvelv
HHVM
eeFa
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| Phosphatase | PTPN5.AA | Subfamily.CDC14.PD | 491-515 | 45 | 1.5e-06 | 19.3 | In-house | 200-224 (258) | Show / Hide |
Range on Protein: 491-515 Range on HMM: 200-224/258 Sequence Identity: 45% (11 aa) PIIVHCSAGIGRTGCFIATSICCQQ |.||| ||.||||..|.. . .. aiavhCkaGLGrtgtligcylikhy |
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| Phosphatase | PTPN5.AA | Subfamily.PTEN.PD | 434-519 | 21 | 3.9e-06 | 17.6 | In-house | 41-124 (305) | Show / Hide |
Range on Protein: 434-519 Range on HMM: 41-124/305 Sequence Identity: 21% (20 aa) DYRLRLISLKSGTEERGLKHYWF----TswpdqktpDRAPPLLHLVREVEEAAQQ--EGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQE ..|| .. .. |. ... . | || |.|..|. | .. . . ..||| || |||| |.. . .. ... kgklrilnargekedsdfdgrvavypfd--------DhnpptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikks |
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