Gene PTPN7
PTPN7
Species: Human
Alias: LC-PTP, BPTP-4, LPTP, PTPNI, HEPTP, PTPN7
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTPN7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PTPN7.AA | PTPc | 135-391 | 35 | 5.6e-122 | 412.44 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 135-391 Range on HMM: 1-308/308 Sequence Identity: 35% (110 aa) QLEEEFLKIPSNFV-----------SPEDLDIPGHA--SKDRYK-TILPNPQSRVCLGRAQSQ----EDGDYINANYIRGYDGKEKVYIATQGPMPNTVS ...||| ....... |.. . | . .| ||| |......||.| . ... |..||||||||.|| ...| ||.||||.|.|.. GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-WRPKRYICTQGPLPHTIE DFWEMVWQEEVSLIVMLTQLRE---------GKEKCVHYWPTEEETYGPFQIRIQDMKECP-EYTVRQLTIQYQE----------ERRSVKHILFSAWPD ||| ||||. .. ||||... | |.||| .||| |..||| ... ... . || .||.|........ | |.|.|. . .||| DFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDEPMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPD HQTPESAGPLLRLVAEVEESPETAAH-----------------PGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQY |..|||. ..|... .|... .. . ||||||||||.||||.|.| | |||... |||..||...| | ||.||.||| HGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQY QFLHHTLALYAG .|... .. |. IFCYRCILEYIK |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N5_RR.PD | 135-390 | 52 | 1.5e-120 | 392.8 | In-house | 1-264 (265) | Show / Hide |
Range on Protein: 135-390 Range on HMM: 1-264/265 Sequence Identity: 52% (139 aa) QLEEEFLKIPSNFvSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQED-GDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVML .||.|||..|.|| |.|.|...|...|.||||||||..|||.| ...|... .|||||||.|||...|.|.|||||.|||..|||.|..||||..|||| dlekeflelPlnf-sqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivml TQLREGKE-KCVHYWPTEEET-----YGPFQIRIQDMKECPEYTVRQLTIQYQEE-RRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHP-GP |.|.| .. ||..|.|..|.. || ..|......|. .|.||.|...|.|. .|||||.....||||..|... .||.||.||||| |..... .| tklkeanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaP IVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYA .||||||||||||||||..|...||.... ||.|.|||.||||||||.||.|||...|..|.||. vvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl |
|||||||||
| Phosphatase | PTPN7.AA | Y_phosphatase | 158-388 | 44 | 1.1e-115 | 395.46 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 158-388 Range on HMM: 1-243/243 Sequence Identity: 44% (108 aa) HASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GK-EK-CVHYWPT----E . .| ||| |... ..||.|.. .. ||.||||||||.|.....| ||.||||||.|. ||| ||||. .. ||||... | |. || | .|||. . NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ EETYGPFQIRIQDMKECPEYTVRQLTIQYQE----ERRSVKHILFSAWPDHQTPES-AGPLLRLVAEVEESPETAAHPG--PIVVHCSAGIGRTGCFIAT ..|||.||. ......||.||||..... . |.|.|.|. . .||||..||| . ..|... .|..... ..| |||||||||.||||.|.| PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-NPDHGCPPIVVHCSAGCGRTGTFCAI RIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLAL | |||... |.|||..||...| | ||.||.|||.|...... DIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.RB.PD | 159-387 | 49 | 2.8e-83 | 270.6 | In-house | 27-257 (261) | Show / Hide |
Range on Protein: 159-387 Range on HMM: 27-257/261 Sequence Identity: 49% (109 aa) ASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKeKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEE--ETYG |.|.. ||| .||| | ....| |||||||| || . . |||||||.|.|| |||.|||....| ||||||| | ||||| .|||..|.|| .. raknrftnilpydhsrvkLaalkdesdtdyinanyipgynsp-reyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYWPadeepvlyG PFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGE .. || |...|...|. ..|.|.|.. | .|||| .||.. .||..| .|.|. |..|. .|||||||||.|||| ||||..... ||..|.|..| dikvtllaekeldewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrllqaieendy VDILGIVCQLRLDRGGMIQTAEQYQFLHHTLA | .| ..|| .|| |.|..|. vdvfgvvaelReeRnllvqtekqyifihecll |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N_Choan_2.PD | 144-390 | 37 | 7.2e-76 | 246.1 | In-house | 6-265 (266) | Show / Hide |
Range on Protein: 144-390 Range on HMM: 6-265/266 Sequence Identity: 37% (96 aa) PSNFVSPEdlDIPGHASK---DRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-G . . || | .|| |.. .||. |||.|..||.| . .... ||||||.||.||..| |||..||.|.|...|| |.|.|.|. |||.|.| | | dkqevsee--aiPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkg KEKCVHYWPTEEETYGPF---QIRIQDMK--ECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAG------PLLRLVAEVEESPETAAHPGPIVV ..|| |||.| .. . .|.. .. | ...|......| |...| . .|||| |....||.....| .. . .. .|..||||||.| rkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllv HCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYA |||..||. |... |. ...||.| |. .|| || ..|. |||..|..... || HcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.R_Anemone_2.PD | 156-387 | 44 | 5.6e-75 | 243.5 | In-house | 25-258 (262) | Show / Hide |
Range on Protein: 156-387 Range on HMM: 25-258/262 Sequence Identity: 44% (103 aa) PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDgKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEE-ET | . |.|| ||. ..|| | ...|. |||||||| || ..| |||||.|.|.|..||| |||. . ..||||||..| || |. .||| .. .. pvnkaknryanilaydktrvklqmlegeegsdyinanyidGyr-rkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWPskgsrs YGPFQIRIQDMKECPEYTVRQLTIQYQ--EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPEtAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLK || .. ... .|. .|..|..... . || | |. . .|||. .|||.. || || .||. . .||||||||||.|||| ||| | ...|| ygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqq-esgagpivvhcsaGvGrtGvfiavdillerik ARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLA . ||....| ||| | |.|| .||.|....| aealvdvfqtvkqlreqrnlmvqtkdqyefiydvll |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.R_Sponge_2.PD | 157-387 | 42 | 2.2e-74 | 241.6 | In-house | 24-258 (262) | Show / Hide |
Range on Protein: 157-387 Range on HMM: 24-258/262 Sequence Identity: 42% (99 aa) GHASKDRYKTILPNPQSRVCLGRaQSQEDGDYINANYIRGYDgKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE---EE .|.|.| ||| .||| | . ..|.|||||... || ..| |||||||...||.||| ||| .|| |||||.|.| |||||..|||.. | .|| envgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgyk-rrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPekvdeev TYGPFQIRIQDMKECPEYTVRQLTIQY---QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESpETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQ |.. ... .. ..|..|.|... .|... |.. | |||.|..|..|..|| |...|... .....|.|.||.|.|||| ||| . ..||| .| eygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlra-qkksgnkaitvvCsdgvgrtGtfialdsvler LKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLA .|. .. .|| | |..|.|.||.|.|. |. lkaeeeidvfevlktlrtkriglvqdaaqYvfihdall |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N12.PD | 156-387 | 41 | 8.4e-73 | 236.1 | In-house | 30-266 (270) | Show / Hide |
Range on Protein: 156-387 Range on HMM: 30-266/270 Sequence Identity: 41% (99 aa) PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKeKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE---E . . |.||| ||| .||| | . ...|. ||||||.|.| .|| . |||.|||.|.|..||| |.|. .|...||. .. | || || .||| | | eenvkknrykDilPydksrvelskieeeegsdyinanfikgvegk-leyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpeegeee ETYGPFQIRIQDMKECP-EYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPEtaAHPGPIVVHCSAGIGRTGCFIATRIGCQQL ..|.|.. .. | . ....|.|... |.|.|.|. . . |||||..|.|| .||.|...|.| | .. |.|||||||.|||| || . ..| lefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqe--sedaPlvvhCsaGvGrtGtiiaidyvrell KARGE---VDILGIVCQLRLDRGGMIQTAEQYQFLHHTLA ||. .|. .| .|| .| ..|| |||.......| kaekipeeldvfdlvlelrkqraalvqtkeqyelvykava |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.R_Anemone_1.PD | 159-386 | 41 | 1.4e-72 | 235.8 | In-house | 26-253 (258) | Show / Hide |
Range on Protein: 159-386 Range on HMM: 26-253/258 Sequence Identity: 41% (95 aa) ASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKeKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEETYGPF .|.||. |.. .||| | . ...|..||||| |.|..|.. . .||||.|...||.||| |||||... |||||.| | |.|| .|||...|.|| .. kkknryadivaldhsRvvLeklsndeesdYinasylrasdkt-rafiatqapleetvedFWrmvwqekigviVmLtnliegekkkchqYwPdstekygel QIRIQDMKECPEYTVRQLTIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESpeTAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGE .... .. .|..|.|... ..|.| | .. | |||. |. | .|.|. .|..| |. |.|||||||.|||| |.. .|.|.. | rvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks--slagarpvvvhCsaGvgRtGaflvidamleqakkekv VDILGIVCQLRLDRGGMIQTAEQYQFLHHTL || .| ..| || |.|| ||| |.|... vDifnyvkairedrphmvqtkeqyvfihlav |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.RA.PD | 135-387 | 40 | 2.6e-69 | 224.8 | In-house | 1-262 (266) | Show / Hide |
Range on Protein: 135-387 Range on HMM: 1-262/266 Sequence Identity: 40% (106 aa) QLEEEFLKIPSNFVSPEDL---DIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKvYIATQGPMPNTVSDFWEMVWQEEVSLIV .||||| |..| . |.| . . |.|. |||. ||| | . .|. ||||| .| || |.| .||.|||. .|| ||| |.|.. . ||| gleeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdk-fiaaqGpkeetvedfwrmiweqksativ MLTQLREGK-EKCVHYWPTEE-ETYGPFQIRIQDMKECPEYTVRQLTIQ------YQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPET-AAH ||.|.| | ||| |||.| ||| .. ..|.... .||||.. .. ... | |. . | .||. | .. .|.|...|.. . |.| mltelkerkeekcaqywpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanh pgPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLA |||||||||.|||| ||. ...|| . .|. ..| .||| | |.|| |||.|....| --pivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvll |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.RK.PD | 156-385 | 36 | 1.8e-68 | 221.9 | In-house | 27-261 (267) | Show / Hide |
Range on Protein: 156-385 Range on HMM: 27-261/267 Sequence Identity: 36% (86 aa) PGHASKDRYKTILPNPQSRVCLGRAQSQeDGDYINANYIRGYDgKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL--REGKEKCVHYWPTEEET . . .|.|.. ||. .|.| | . . . |||||..| .| . . .|.||||...|| ||| .|..|. . |||||.| .|. ||..||| . |. drnreknrsmdilaydrslvflisvdgd-ssdyinaalidsyk-rpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyWPedtev -YGPFQIRIQDMKECPEYTVRQLTIQY----QEERRSVKHILFSAWPDH-QTPESAGPLLRLVAEVEESPETaAHPGPIVVHCSAGIGRTGCFIATRIGC ||.... . ... .. || .... |||.| |... | .||.. ..|.|. ||.|...|..| | .. |.|||||.|| ||.|.||| | . rygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee-eeeGrivvhClaGaGrsGtfiaidivl QQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT . .. .| ||. .| .|| . |..| |||.|.. emieregvvdvfnavktlrnrkvnmveteeqykfvydv |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N3.PD | 156-385 | 38 | 6.2e-67 | 216.8 | In-house | 24-255 (261) | Show / Hide |
Range on Protein: 156-385 Range on HMM: 24-255/261 Sequence Identity: 38% (91 aa) PGHASKDRYKTILPNPQSRVCLGRAQSqedgDYINANYIR-GYDGKEKV--YIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLR-EGKEKCVHYWPTEE | ..|.||. ||| . || | ... |||||||. .... | |||||||...|..|||.|||.....||||||.| .|. || .|||..| penlaknryrdilpydatrvklkeset----dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqyWPete E--TYGPFQIRIQDMKECPEYTVRQLTIQYQE--ERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPetAAHPGPIVVHCSAGIGRTGCFIATRIGC . ..| |..|.. .| .| .|.|... .| |.|.. .. . |||||. |... .|..| .|.. ... |.|||||||||||| .|. . delefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr--sgkeePvvvhCsaGigrtGvlilletal QQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT . . |. .| .| || ..| |. ..||..||.|. .. alieaaepvypldivrtmrdqramlvqtvsqykfvCea |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N_Choan_1.PD | 159-387 | 36 | 1.4e-66 | 215.9 | In-house | 27-258 (262) | Show / Hide |
Range on Protein: 159-387 Range on HMM: 27-258/262 Sequence Identity: 36% (83 aa) ASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKvYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQ-LREGKEKCVHYWPTEE--ETYG |.||. | ..|| . . ..... ||||||.. ||.|... |||||||.|... .||.|||...||.|||.|. . .|| ||.||| |. ..| .. vlknrysnivayDatrvkvtpneenkntDyinanfvpgykgeke-yiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWPdenselklg PFQIRIQDMKECPEYTVRQLTI-QYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHpGPIVVHCSAGIGRTGCFIATRIGCQQLKARG .. . .| ..| |.... . . | |.|... . ||||| |... || ..|.. .. . |.|.|||||.||||..|| ....... |. dvtvkslseeekktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk-aplvihCsaGvGrtGtyialDrlvkaveeka EV-DILGIVCQLRLDRGGMIQTAEQYQFLHHTLA |. .| .|| .| |.|| ||.|..... ealdvkavvaelrkernlmvqtlvqyefvykavl |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N6.PD | 156-389 | 39 | 2.7e-66 | 215.1 | In-house | 38-293 (295) | Show / Hide |
Range on Protein: 156-389 Range on HMM: 38-293/295 Sequence Identity: 39% (100 aa) PGHASKDRYKTILPNPQSRVCLGRAQSQEDG-DYINANYIR--------GYDG----KEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL-REGKE . ..| ||| ||| ..|| | ... | ||||||||| | . | ||||||....||||||.|||||. .|||.|.||.||.. ienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqensrvivmttkevergkn KCVHYWPTEEE--TYGPFQIRIQDMKECPEYTVRQLTIQY---QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGR |||.||. ..| ... . |. .||.|..... ..| |.. . | ||||| .|...| .| .. .|.. |. ..||||||||||||||| | kCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeelekagpivvhcsaGiGr TGCFIATRIGCQQLKARG---EVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALY | | .... .| ..|| .. ..| | |..||..||.|. .... | tGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfy |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.RG.PD | 159-387 | 35 | 5.2e-66 | 214.1 | In-house | 28-260 (264) | Show / Hide |
Range on Protein: 159-387 Range on HMM: 28-260/264 Sequence Identity: 35% (82 aa) ASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDgKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPT--EEETYG |.|. |.. .||| | ... |||||.||.|| ..| ||.||||...|. ||| |.|......|||||.| | .... |||.| .... ... keknReinivaversRvklsplpgkdgkDYinAsyidGyr-rskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrdedvyWPkkdeplele PFQIRIQDMKECPEYTVRQLTIQYQE----ERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESpeTAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLK .. . .. .||||..... .. ..| |.. .. |||...|||. . | | | . . .. ||||||.||| ||.|.|| |||... | alkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaa--nkeeaGPivvhdsaGvgragtyialdtllqqle ARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLA ...... ..|. | |...| |||.|....| keeavnvyqvlklirakRpglvtteEqyvfiydall |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.R_Ecdysozoa.PD | 136-389 | 37 | 7.3e-66 | 213.4 | In-house | 2-267 (269) | Show / Hide |
Range on Protein: 136-389 Range on HMM: 2-267/269 Sequence Identity: 37% (101 aa) LEEEFLKIPSNFVSPEDLDI---PGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKeKVYIATQGPMPNTVSDFWEMVWQEEVSLIVM ||||. |.... .. . . | |.||. | . . || | . . .|| |||||..|.||. | | .|| |.|. .|. ||| |... || |||| leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykek-kkfiaaqdPveatigDfWrmiaeqevtlivm LTQLREGKEKCVHYWP-TEEETYGPFQIRIQDMKECPEYTVRQLTIQYQE-----ERRSVKHILFSAWP-DHQTPESAGPLLRLVAEVEESPETA---AH |..| | ..|| .||| .| || ... . .....|. |.|.. .. ..| | . .|.| . ||.| ||.|. .|.| ... lsnlteknrkcakyWpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgs PGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALY .||||||||| ||.| |.| . ||||| .|||. .|..|| .| ..| |||.||.. || | rsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralady |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N9.PD | 155-390 | 41 | 1.2e-65 | 212.9 | In-house | 23-274 (275) | Show / Hide |
Range on Protein: 155-390 Range on HMM: 23-274/275 Sequence Identity: 41% (104 aa) IPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDgKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET ... .|.||. .| ..|| | . . .| ||||||.. || ..| .||||||...|||||| |||..|| ||| |.. | |. || .|||.|||. lranleknrytdvlcydetrvklakldedeasdyinanfvdGyk-qkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywpleees ---YGPFQIRIQDMKECPEYTVRQLTIQ--YQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEES-----------PETAAHPGPIVVHCSAGIGRT .| .... .... .|.||.|.|. .|| |.| | | .|||. .|.|| || .. .| | . .. ||||||||||||| saefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGrt GCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYA | ||. | ..|. | ||. | .|| | .||| |||.| . .. || Gtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N13.PD | 158-385 | 37 | 2.9e-61 | 198.5 | In-house | 26-253 (259) | Show / Hide |
Range on Protein: 158-385 Range on HMM: 26-253/259 Sequence Identity: 37% (89 aa) HASKDRYKTILPNPQSRVCLGRAQSqedgdYINANYIRGYDGKEK-VYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEE--- . .|.||. .|| ..|| || . ||||..|. |... .|||.|||.|.||.||| |||. ....|.|.|. .| || || |||... nkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerknkkl -TYGPFQIRIQDMKECPEYTVRQLTIQYQEE--RRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPEtaaHPGPIVVHCSAGIGRTGCFIATRIGCQQ .. .... .... ...||.|... .| | | |. | .||||..| || .|...|||| . . . |||||||||||||.| .|. . . . kvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt---dagPivvhcsaGiGrsGvlitidvvlgl LKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT . |.|. || .|| | |..|| .|| | ... ierdkefdvkeivrklreqrqgvvqtkdqyifvyka |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.RC.PD | 180-389 | 35 | 5.1e-59 | 191.1 | In-house | 67-286 (288) | Show / Hide |
Range on Protein: 180-389 Range on HMM: 67-286/288 Sequence Identity: 35% (79 aa) AQSQEDGDYINANYIRGYDgKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQ ..|.| .|||| .| .| | ..|||.|||. .|| |||.|.... | .|||||.|.|| .||| .|| ...|| .. ..| . ...|..|.| .. idseegskyinasfidsyk-kpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrekcaeyweeGkrayGdvevdlkdtdkssdyilrklelv YQEER--RSVKHILFSAWPDHQTPESAGPLLRLVAEVE------ESPETAA--HPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLD . .. | | .| ...|...| || ||.|. |. .| |. . .|..|||..| .||| ||| . |.| ||. ..| .|| . nkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrka RGGMIQTAEQYQFLHHTLALY | .|... |||..|...|. . rplmvsveeqyillydvlvet |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N14.PD | 155-387 | 34 | 3.7e-55 | 178.3 | In-house | 23-271 (275) | Show / Hide |
Range on Protein: 155-387 Range on HMM: 23-271/275 Sequence Identity: 34% (85 aa) IPGHASKDRYKTILPNPQSRVCLGRAQSQeDGDYINANYIRG-YDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL-REGKEKCVHYWPTE-- .| |.|.|.| .|| ..|| | .. . . .|||| |. |||. ||..|||...|| |||.|||...|.||||||. .||||...|.| . lpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeksfkylPkles ---EETYGPFQIRIQDMKECPEYTVRQLTIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEES---PET-----AAHPGPIVVHCSAGIGRT . ..| |.. . .. . .. ..|.... .|.|.| |. . ||||. || ..| . ||. .. .|..||||||.|||| kkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrt GCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLA | . . . |. |.|| .. .|| | ..|| ||.|....| GvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvli |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N23.PD | 172-385 | 35 | 5.4e-53 | 171.5 | In-house | 116-344 (350) | Show / Hide |
Range on Protein: 172-385 Range on HMM: 116-344/350 Sequence Identity: 35% (79 aa) QSRVCLG-RAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPTEEE---TYGPFQIRIQDMKE ..||.| .| .. ||||| |.. .||||||...|..||| |||.. .|.|||||. || | ||..|||..|. ..|.......... pnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrs CPEYTVRQLTIQYQEE--RRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESP------ETAAHPG-PIVVHCSAGIGRTGCFIATRIGCQQLKA-RGEV ... |.|..| .. |.|.|. . .|... |.| . ||... |||. ||. .| ||..|||||.|||| |..|.| .| ..|. .| . segwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngii DILGIVCQLRLDRGGMIQTAEQYQFLHHT || .| |.|. .....| . niprvvrrlrqqRkymvqkkvilkklyea |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.RN.PD | 157-386 | 38 | 3e-51 | 165.5 | In-house | 26-259 (264) | Show / Hide |
Range on Protein: 157-386 Range on HMM: 26-259/264 Sequence Identity: 38% (89 aa) GHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTE-EETY ..|.|.|..|| .||| | . .|.|. ||||| | | .. .|||||||...|..|||.|||.. | .||.||.|.| | ..| .|||| .|.|. . knvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevy GPFQIRI-QDMKECPEYTVRQLTIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETaaHPGPIVVHCSAGIGRTGCFIATRIGCQQL- .... . | .| || . .. ..| |.| | .||....| || .|| . |. | |||||||.| ||||..|. . ...| | hiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG--rscpivvhcsdGaGrtGvyilidlvlerll KARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL |.|| . || .| |...| .|..| .. kGvkeidiaatlehlrdqrpglvktkdqfefaltav |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N_Nematode_4.PD | 158-386 | 34 | 1e-49 | 160.5 | In-house | 26-259 (264) | Show / Hide |
Range on Protein: 158-386 Range on HMM: 26-259/264 Sequence Identity: 34% (82 aa) HASKDRYKTILPNPQSRVCLGRaqSQEDGDYINANYIRGYDGkeKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET--- .. | ||. || ..|| | . | ||| |...| |. ||.||||...|.|||| ||..| .. .||| .| | |||| |.| ..|. . nsdknryadilcidetrvvlkn--rdpdndyihaswmrmPdk--fryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvk YGPFQIRIQDMKEC--PEYTVRQLTIQYQE---ERRS----VKHILFSAWPDHQTPESAGPLLRLVAEVEEspetAAHPGPIVVHCSAGIGRTGCFIATR | ..|.. . || . .. |.. | . | |||. .. |.|. .|. | |...|| . ...|||||||||.||| .. .. . fGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk----kkkekPivvhcsaGvGrtatlvGid IGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTL ... .|...| || .|| | . .|. |. || | yatirirenseievldivrelramrlkavqshlqflfllvvl |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N1.PD | 155-382 | 33 | 2.6e-47 | 152.8 | In-house | 25-259 (268) | Show / Hide |
Range on Protein: 155-382 Range on HMM: 25-259/268 Sequence Identity: 33% (79 aa) IPGHASKDRYKTILPNPQSRVCLGRAQSqedgDYINANYIRgYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEET | ...||. . | ||. | ||. |||||. . . .. || ||||.|.|.. ||.|||... ..|| .. | .. ||..|||.|||. lpenrglnryrdvspydhsrikleradv----dyinaslve-leeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqeeee ----YGP--FQIRIQDMKECPEYTVRQLTIQY--QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRI . ..... .. ...||.| .. ..| | . | ... ||| ||| .|... .| || . . ||.|.||||||||.| . aellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtlslvdt GCQQLKARGE---VDILGIVCQLRLDRGGMIQTAEQYQFL .. ..|. ||| ...|| | |.|||..| .| clveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFs |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N20.PD | 142-383 | 37 | 4.6e-47 | 152.0 | In-house | 13-249 (257) | Show / Hide |
Range on Protein: 142-383 Range on HMM: 13-249/257 Sequence Identity: 37% (93 aa) KIPSNFVSPEDldiPGHASKDRYKTILPNPQSRVCLGRAQsqedgDYINANYIRGYD-GKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-G ..| .| | .. | |.||. ||| .|| ||... |||||.||| . |.| .|||||||. .|. |||.|| ... .| |.|. | | nlpgefnsgnq---psnreknryrdilpydstrvplgksk-----dyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreiegg KEKCVHYWPTEEE---TYGPFQIRIQDMKECPEYTVRQLTIQ--YQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETaahpGPIVVHCSAGI || |||| . |.. ... . . .| . . .|||.. |. |||| || || ... . .| |||.|||||||||||| iikcyhywpislkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshlt----gpmvvhcsagi GRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLH |.. . . ..|. ||.|.| .| ||.|| |||.| . grtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcy |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.R_Nematode_2.PD | 158-385 | 34 | 1.4e-45 | 146.8 | In-house | 29-255 (261) | Show / Hide |
Range on Protein: 158-385 Range on HMM: 29-255/261 Sequence Identity: 34% (81 aa) HASKDRYKTILPNPQSRVCLGRAQSQEDgdyINANYIRGyDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEE---T .. |.||... .|...| . . | ||.. .|..| .||||||. ||..||| || ||.| ||||.| | |||| .|.|.|.. . pkdkhRypdvPCkpetavevivdgkrvp---ihanwvpt-agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkld YGPFQIRIQDMKECPEYTV--RQLTIQYQEE---RRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPEtaahpgPIVVHCSAGIGRTGCFIATRIGCQ | |.|....... . . |.| .. .. |.|.| .. |||...|.| | |. | .|. |||||||||||||. ||.| .. lgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek------PivvhCsaGiGRtmafigteylar QLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT ..| .. . . .|| | ||| .|. .|. . eveadptieltealkelrehRwkgiqtesqlywltlg |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.R_Nematode_3.PD | 157-383 | 29 | 9.1e-44 | 141.1 | In-house | 22-259 (267) | Show / Hide |
Range on Protein: 157-383 Range on HMM: 22-259/267 Sequence Identity: 29% (71 aa) GHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEkvYIATQGPM--------PNTVSDFWEMVWQEEVSLIVMLTQLRE----GKEKCV . |.||..... ....|| | ... |.|.||.. .| . | ||.|. .|. || |. ||.| .||| . | ..||| . kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpnglk--lIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcs HYWPTEEET---YGPFQIRIQDMKECP--EYTVRQLTIQYQ-EERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPeTaahpgPIVVHCSAGIGRTG |.|..... . .... |.|. . . |.|..... .. |.| |...|.....||.. ..| |. ||.| | |.|||||.||.|... eYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfveksk-t-----pvvVHCsdGisRsa CFIATRIGCQQ-LKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLH . |. .|.| .| .|..|.| ....|| | | |||.... |. tlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvi |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N_Nematode_1.PD | 158-388 | 36 | 2e-43 | 139.9 | In-house | 26-262 (265) | Show / Hide |
Range on Protein: 158-388 Range on HMM: 26-262/265 Sequence Identity: 36% (88 aa) HASKDRYKTILPNPQSRVCLGRAqsQEDGDYINANYIrGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCVHYWPTEEETYGP .|.|.||| . ..|| | . ||| |||. | . | .| .|.|. .|..||| || ||.| |||| .| | |||| .|.|..|. | eadknrykdvgcldknrvklaee--plpsdyihanyv-gtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegekle FQ-----IRI------QDMKECPE-YTVRQLTIQY-QEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESpetaahPGPIVVHCSAGIGRTGCFIAT . | . . ..| | .| .|.... |. |.|.|. .. |||. |. | |...|..| ||||||||||||||| .| fkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgs------kgPivvhCsaGiGrtGtivai RIGCQQLKARGEV-DILGIVCQLRLDRGGMIQTAEQYQFLHHTLAL ...| . .. |. .| ..| .| ||| || |.|. | eyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvlln |
|||||||||
| Phosphatase | PTPN7.AA | PTPc_motif | 285-388 | 37 | 1.8e-39 | 138.33 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 285-388 Range on HMM: 1-92/92 Sequence Identity: 37% (41 aa) SVKHILFSAWPDH-----QTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQY .|.| . .|||| .|| ..|.....|.. |||||||||.||||.|.| . .|| |||...|...| | ||.|| ||| TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQY QFLHHTLAL .|... .. IFCYRCILE |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N_Nematode_5.PD | 160-389 | 27 | 8.7e-39 | 124.6 | In-house | 27-256 (258) | Show / Hide |
Range on Protein: 160-389 Range on HMM: 27-256/258 Sequence Identity: 27% (65 aa) SKDRYKTILPNPQSRVclgrAQSQEDGDYINANYIRGYDGKEkVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPF-- .| |.| . . ..|| ...|| .||||..|. | .. .| || | |.|..|||.|| ||.. ..|.|.. | ||.|...|.|...| . kknrskdvkilDetrV----kltdeddsYinaskiklddlek-kliltQlPlpdteedFWrmvyqekitsvvllvedeelketavsffpletgdylnlgk -QIR---IQDMKEC-PEYTVRQLTIQYQEErRSVKHILFSAWPDHQTPESAGPLLRlVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKA |. .. .... |||| | . |. .|. .. |.... |.. .... .| ... .... |.||....|.||.| |... . ..||.. mfinnrkvevkedekkeytvevlpegcses-vfakvyhlttWkkkkvPdkvkkvik-raiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnn RGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALY |..| |. ..| | |..... || ... ... | gkepnideilkkirsqRpgavesliqyasvyaavldy |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N_Nematode_6.PD | 160-385 | 31 | 4.2e-34 | 109.4 | In-house | 26-247 (253) | Show / Hide |
Range on Protein: 160-385 Range on HMM: 26-247/253 Sequence Identity: 31% (70 aa) SKDRYKTILPNPQSRVCLgraqSQEDGDYINANYIRGYdGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQL-REGKEKCVHYWPT---EEETYG ..||. | ..|. | .... || ||... |.. .| ||.|. .|. .||.|. | |||| .| .||||. .| . .. .. drnrytniqCcdagrlkl----addedfyihanlvkis-tkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarkit PFQIRIQDMKECP-EYTVRQLT--IQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEEspetaaHPGPIVVHCSAGIGRTGCFIATRIGCQQLKA . |. .. .|| | . .| |||| . .|||| |.| |||.. | .. |||||||||.|||| .. | . |. .. klctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkk------dkkPivvhCsaGvGrtGtlaliliilealrl RGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHT .. .|| .| .|| || . .. pdfqgvkdllvklreerfravqtevqylyalrc |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N_Nematode_egg.PD | 160-389 | 28 | 2.5e-29 | 93.8 | In-house | 28-255 (257) | Show / Hide |
Range on Protein: 160-389 Range on HMM: 28-255/257 Sequence Identity: 28% (68 aa) SKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGkEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGkEKCVHYWPTEEETYG---P | | | . . ||| | . | .|.| ||...| .| .| |. ||| ||| ||.||.| ||||| .| |.| .||| |. | ekarskrvhckessrvklelrrGqylddfihanrvkGkpl-lnefilaqaplkntvedfwrmvfqekvqyivmltsakes-erceyywpkaeseslvtvp FQIRIQDM----KECPEYTVRQLTI-QYQEERRSVKHIlfsAWPDHQTPESAGPLlRLVAEVEESPEtaahpgPIVVHCSAGIGRTGCFIATRIGCQQLk .||. . | | ..| .| . ..| . ..| . ... . || |.. . .. |.||.. |. ......| | .| || GslrienlkvdskadplfrvtklklvGgddeelflehw---qgdvnylsdvyspl-rvlrklrnlsk------pvvvqdilGvskaatlvaieiallsl- ARGEV---DILGIVCQLRLDRGGMIQTAEQYQFLHHTLALY . .| | ||| | .... .| |.. .. . lrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlff |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N_Fungi_PTP1.PD | 159-268 | 34 | 1e-25 | 81.7 | In-house | 46-167 (343) | Show / Hide |
Range on Protein: 159-268 Range on HMM: 46-167/343 Sequence Identity: 34% (43 aa) ASKDRYKTILPNPQSRVCLG--------RAQSQEDGDYINANYIRGY----DGKEKV-YIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE-GKEKCV .|.||| ||| .||| | . | . |||||||.. . . . |||||.|.|.|| ||.... . .| .|..||.. | . ||| . faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy HYWPteEETYGPFQIRIQDMKECP ||. | .| .........| . rYWq--egsydditvklaskweni |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N_Nematode_eak.PD | 162-301 | 27 | 9.8e-14 | 42.6 | In-house | 30-171 (281) | Show / Hide |
Range on Protein: 162-301 Range on HMM: 30-171/281 Sequence Identity: 27% (38 aa) DRYKTILPNPQSRVCLGRAQSQEDGdYINANYIRgYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT-QLREGKEKCVHYWPT--EEETYGPFQ .| |.|. . | | .| ..|| |||| . . . || | . . | ||.|| .. ||.| .. |. |||.| |. || ... nrvvkivpqdrylvrltssqlnrdG-yinaslae-fsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevlkyGild IRIQDM-KECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPE .. . . .|.| .. .| |.| . | . ..| verkeyavkrniletrllilrkGnethrvlhykvfGwtettlpk |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.N_Fungi_PTP1.PD | 285-389 | 31 | 1e-10 | 32.4 | In-house | 214-341 (343) | Show / Hide |
Range on Protein: 285-389 Range on HMM: 214-341/343 Sequence Identity: 31% (36 aa) SVKHILFSAWPDH---QTPESAGPLLR----LV-AEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQ-------------QLKARGE--VDILGI | .. . |.| ||| . | |. . || |. ||.||||||.|||| ... ..|. . | || .|| .| |.|. evyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisii VCQLRLDRGGMIQTAEQYQFLHHTLALY .|. |....| | vnelrkqrismvqnldqfifiYeallfy |
|||||||||
| Phosphatase | PTPN7.AA | Family.DSP.PD | 224-378 | 17 | 1.5e-09 | 29.0 | In-house | 130-235 (387) | Show / Hide |
Range on Protein: 224-378 Range on HMM: 130-235/387 Sequence Identity: 17% (28 aa) QEEVSLIVMLTqlregkekcvhywpteeetygpfqiriqdmK------EcpeytvrqltiqyqeeRRSVKHILFsAWPDHQTPESAGPLLRLVAEVEESP . |. || || . . . ..|.. . ...||..| . . . . .||.. elgvtkivnlt------------------------------ddkpqftk----------------elgikylri-pidDhnapplenlfekaidfieegn EtaaHPGPIVVHCSAGIGRTGCFI-ATRIGCQQLKARgevDILGIVCQLRldrGGMIQTAEQ . . | ..||| ||.||.| | | .. ...|.. . | | . | |.|. .. d---skgvVlVHCkaGkgRsgtliiaYlmksegltle---ealdwvrskR---pgvitpnqg |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.PTPDC1.PD | 283-384 | 30 | 1.2e-08 | 26.0 | In-house | 132-222 (229) | Show / Hide |
Range on Protein: 283-384 Range on HMM: 132-222/229 Sequence Identity: 30% (30 aa) RRSVKHILFsAWPDHQTPeSAGPLLRLVAEVEespeTAAHPGPIVVHCSAGIGRTGCFIATRIG-CQQLKARGevdilgIVCQLRLDRGGMIQTAEQYQF |. . . | ...|.... | .| .| |. | . | | ||| || |||| ||. . ..|.| . ..| |||| || ..... rqgiyfynf-glkDygva-sleriLdivkvvd----faleegkiavHCHAGlGRtGvliacylvyakrltaee------aiklvrskrpksiqtreqvel LHH vee |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.CDC14.PD | 323-384 | 31 | 1.6e-08 | 25.8 | In-house | 198-253 (258) | Show / Hide |
Range on Protein: 323-384 Range on HMM: 198-253/258 Sequence Identity: 31% (19 aa) PGPIVVHCSAGIGRTGCFIATRIgcqqLKARgEVDILGIVCQLRLDRGGMIQTaEQYQFLHH | |.||| ||.||||..|.. . .| .. .. ||. | |.. . | ..| . eGaiavhCkaGLGrtgtligcyl----ikhy-rftaaetiawlriarPGsvig-pqqtylve |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.DSP23.PD | 303-382 | 32 | 7.2e-08 | 23.9 | In-house | 49-120 (128) | Show / Hide |
Range on Protein: 303-382 Range on HMM: 49-120/128 Sequence Identity: 32% (25 aa) AGPLLRLVAEVEEspeTAAHPGPIVVHCSAGIGRTGCFIAtrigCQQLKARGEVDIlGIVCQLRLDRGGMIQTAEQYQFL . ||| ||| . .. ... ||| |.|||| ..| | .| .| . ..| | | |.| || . . leqvarlvrivee---aekkeeavgvhcalGlGrtGtlla----cylvkeeglaad-daiaevrkrrkGsietveqekav |
|||||||||
| Phosphatase | PTPN7.AA | Subfamily.PTEN.PD | 269-344 | 25 | 8.5e-06 | 16.6 | In-house | 41-115 (305) | Show / Hide |
Range on Protein: 269-344 Range on HMM: 41-115/305 Sequence Identity: 25% (19 aa) EYTVRQLTIQYQEERRSV-KHILFSAWPDHQTPEsAGPLLRLVAEVEESPETAAhPGPIVVHCSAGIGRTGCFIATR .. .|.|... ..| . ... . ||. |. | ..| .|.. . ..||| || |||| |.. kgklrilnargekedsdfdgrvavypfdDhnppt-leLleeivedvdkwLkedk-snVvavHCkaGkGRtGvmicay |
|||||||||