Gene PTPN9
PTPN9
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTPN9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| CRAL_TRIO_N | PTPN9.AA | CRAL_TRIO_N | 20-68 | 20 | 1.7e-07 | 30.33 | Pfam | 1-58 (58) | Show / Hide |
Range on Protein: 20-68 Range on HMM: 1-58/58 Sequence Identity: 20% (12 aa) EQATKQFLEEINKWT--VQYNVSPL-------SWNVAVKFLMARKFDVLRAIELFHSY ... |.|.. . .|. . .. . | .|| |||.|| .|....... QEKYKEFRQWLQDWSPFWDMKKCDHPLDEKWLDDNCLLRFLRARKWDVEKAFKMLKNT |
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| Sec14_4 | PTPN9.AA | SEC14 | 90-240 | 23 | 3.8e-41 | 143.93 | SMART | 1-184 (184) | Show / Hide |
Range on Protein: 90-240 Range on HMM: 1-184/184 Sequence Identity: 23% (43 aa) EILSGKFTILNVR-------DPTGASIALFTARLHH----PHKSVQHVVLQALFYLLDRAVDS-------FETQRNGLVFIYDMCGSNYAN---FELDLG |. .||. .. .| |. | . .| |..|. .|. .| .|....|........ .....|...|.|| |..... . ... EHECGKHYMPGGRHGTRQGYDKDGRPVYYFRAGRHDPKGMMHSCTMHEFLRYHVYVMEKMCQHCPMCMEKMPGGQCGFHWIFDMKGWSMSHFWSPDWGWY KKVLNLLKGAFPARLKKVLIVGAPIW---FRVPYSIISLLLKDKVRERIQILK---------TSEVTQHLPRECLPENLGGYVK .|..... ..|.||.||.|. .| | |.|....|. .|..|.||.| ... .|.......|||||..||. . RKMWQIFQDHYPERLHKVYIINPPWWMFFFWVWWKMIKPFLDEKTREKIHFVGPNKVDDNDWKEELHKYIDPECLPEEWGGTCD |
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| Phosphatase | PTPN9.AA | Subfamily.N6.PD | 297-574 | 33 | 2.9e-63 | 205.1 | In-house | 8-293 (295) | Show / Hide |
Range on Protein: 297-574 Range on HMM: 8-293/295 Sequence Identity: 33% (99 aa) ARQKQGIYEEYEDIRRENPVGTFHCS--MSPGNLEKNRYGDVPCLDQTRVKLTKR-SGHTQTDYINASFM--------DGYKQK-----NAYIGTQGPLE | |..||.| . ... .. .. . | ||||| .. |.|||.|. . . . .|||||... .| ... . |||||.|..| ksqtlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLk NTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIrFGFLTVTNLGVENMNHYKKTTLEI-HNTEERQKRQVTHFQFLSWPDYGVPSSAAS ||| |||... ||||||. | |. || .||| |.... .| .|||.. .....|. .... |. .....|.. ...| .||| |||... ... dtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkke-tGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgv LIDFLRVVRNQQSLAvsnmgarskgqCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGT---LNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF ||. |...|. . |||||||||||||||| .|| | ..|. |. ... ... ..|.||. .|| .|| | |||. . vlnfledvnkkqeel-----------ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfy |
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| Sec14_4 | PTPN9.AA | CRAL_TRIO | 109-238 | 26 | 3.4e-39 | 137.88 | Pfam | 1-145 (145) | Show / Hide |
Range on Protein: 109-238 Range on HMM: 1-145/145 Sequence Identity: 26% (38 aa) IAL---FTARLHHPHKS----VQHVVLQALFYLLDRAVDSFETQ--RNGLVFIYDMCG---SNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFR . .. ..| ..| .. ....|.|...|. | |.| ..|...|.|| | ....|. ... |....... .| ||....|. || ||. CIYWYHIRPHRHWDKKQFMCCTSEEMIRFLVYMCERMMDYMEPQGKIEGWTVIFDMKGLTMKHMWNMDYSMMKFMIQCFQDHYPERLGRMHIHNAPWWFW VPYSIISLLLKDKVRERIQILKT---SEVTQHLPRECLPENLGGY | ..||. ... |.||.|...|. .| .| |...||...|| VIWKIIKPFIDPKTREKIHFHKNNWFEELHKHIPPDQLPKEYGGT |
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| Phosphatase | PTPN9.AA | Subfamily.N9.PD | 302-576 | 64 | 1.7e-149 | 488.0 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 302-576 Range on HMM: 1-275/275 Sequence Identity: 64% (177 aa) GIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMT |...||.|||.|...|||..|....||||||| || |.|.|||||.|.......|||||.|.||||||.|.|.|||||..|..|||.|||||.||||||| GlskeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmt TRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGAR ||..| ||.|||||||||..|...||.|.|.|..||....||...|||.|......|.|||||||||||||||||||||.|.|..||..|.|||...|.. trvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde SKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAE |||.. .|||||||||||||||||..||||||.|||.||..|..||...||||||||||||||.|||.|.||.|. skghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyal |
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| Phosphatase | PTPN9.AA | PTPc | 302-576 | 41 | 1.1e-140 | 474.55 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 302-576 Range on HMM: 1-308/308 Sequence Identity: 41% (131 aa) GIYEEYEDIRRENPVG---------TFHCSMSPGNL--EKNRYG-DVPCLDQTRVKLTKRSGH----TQTDYINASFMDGYKQKNAYIGTQGPLENTYRD |. ||.|...|..| .. |. .| | .|||| |.|| |.|||||... |. .|||||...|||.....|| |||||..| | GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED FWLMVWEQKVLVIVMTTRFEEG--------GRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMN-HYKKTTLEIHNTEE--------RQKRQVTHFQFLSW || |||.||. .||| ....|. ||.|| ||||.| .| .|||.. .|... .|. .|.|. ||.. ..|.|||... .| FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNW PDYGVPSSAASLIDFLRVVRNQQSLA-------VSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTP || |||.|. |..||.|.||..|| ||... . ..||..|||||||||.|||||||..||.. |.|. ...||.|..||.||....||. PDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNS-KYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTE EQYYFCYKAILEFAE |||.|||..|||... EQYIFCYRCILEYIK |
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| Phosphatase | PTPN9.AA | Y_phosphatase | 327-573 | 46 | 1.3e-127 | 435.04 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 327-573 Range on HMM: 1-243/243 Sequence Identity: 46% (118 aa) NLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDG-YKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGR-RK-CGQYWPL-EKDS |.||||| |.||.|.|||||. |. ..|||||...|| |....||| ||||...| ||| |||.||. .||| ....|.|| .| | ||||. ... NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ RIRFGFLTVTNLGVENMNHYKKTTLEIHNTEE--RQKRQVTHFQFLSWPDYGVPSS-AASLIDFLRVVRNQQSLAVSNMGARSKGQCPEP--PIVVHCSA ...| ..||. .| ...| .|.|. | .. ...|.|||.....|||.|||.| . |..||.| ||..|. .. . |||||||| PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP------------NPDHGCPPIVVHCSA GIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILE |.|||||||..||.. |.|. ||...||.|..||.||....||.|||.|||..||| GCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | PTPN9.AA | Subfamily.R_Anemone_2.PD | 304-574 | 43 | 1.9e-85 | 277.8 | In-house | 3-260 (262) | Show / Hide |
Range on Protein: 304-574 Range on HMM: 3-260/262 Sequence Identity: 43% (116 aa) YEEYEDI-RRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTT |||| . | |. |.. ...| | |||| .. |.|||||....|....|||||...|||..|.||| ||.|| .| .||||||||. |||| |. seeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmlt RFEEGGRRKCGQYWPLEKdsRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSlavsnmgars || |..|. .||| .. . .| |.|. ....| ......||| ..||| |.. |||| |||.|.|||.|..| |.. | qeeergkakvhryWPskg--srsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqq---------- kgQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF .. . |||||||||.||||.|. .|| | .... ....|||||...|.||.|| .|| |.|...||. --esgagpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvllea |
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| Phosphatase | PTPN9.AA | Subfamily.RB.PD | 304-575 | 38 | 6.9e-81 | 262.7 | In-house | 3-260 (261) | Show / Hide |
Range on Protein: 304-575 Range on HMM: 3-260/261 Sequence Identity: 38% (101 aa) YEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTR ||||.... . . . . .. | .|||. . |..||||.. . ...||||||....||.... || |||||..| ||| ||||.|. .||| |. seeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltq FEEGGRRKCGQYWPLEKDSrIRFGFLTVTNLGVENMNHYKKTTLEIHNteERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQslavsnmgarsK |.|. || .||| .... . .| ..|| | ...... ...|.. ...||.|....|.||||.|||.....|.||.| ||... .. . ||||||| lvEkgkekceeYWPadeep-vlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreai-----------e GQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFA ||.|||||| .|| | ..|| ...|| .|...|..|.. .|| .|| | ....|... kkaskkPivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldll |
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| Phosphatase | PTPN9.AA | Subfamily.R_Sponge_2.PD | 305-575 | 37 | 5.8e-79 | 256.5 | In-house | 3-261 (262) | Show / Hide |
Range on Protein: 305-575 Range on HMM: 3-261/262 Sequence Identity: 37% (101 aa) EEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKrSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRF || |. ... .... . .. |. |||. .. .|..||.|.. .|....|||||||.||||...||| |||||..| ||| ||||.|| ||| | eeeeksveketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnl EEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQK-RQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSlavsnmgaRSK || |. || .||| ..| . ..| .|| |....|. .|.. ....... ..||.|.|..||. .||..|.||..... |...| .|. eengkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqk--------ksg GQcpepPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFA .. .|.|.||.|.||||||. ||. | .|.. ....||... .||.| . .|..|| |...|.||. nk----aitvvCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi |
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| Phosphatase | PTPN9.AA | Subfamily.N_Choan_1.PD | 302-574 | 38 | 1.5e-76 | 248.5 | In-house | 1-260 (262) | Show / Hide |
Range on Protein: 302-574
Range on HMM: 1-260/262
Sequence Identity: 38% (104 aa)
GIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMT
| ||||... . | . | .. | .|||| .. |.||||.|. . ...||||||.|..|||....|| ||||. .. .||||||||| .||| |
GfieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmv
TRFEEGGRRKCGQYWPlEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIhNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSnmgar
| |.|. || .||| ...|....| .||..| |. ..| . .... ..|. ..|.|.......||| |||.... |..| . |.....
treieagklkChryWP-denselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk-----
skgqcpePPIVVHCSAGIGRTGTFCSLDICLAQLEE-LGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF
|.|.|||||.|||||. .|| . ..|| . .|.| ..|. .| .| . .|||| | |||.|.
-------aplvihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavlda
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| Phosphatase | PTPN9.AA | Subfamily.RA.PD | 316-575 | 40 | 1.7e-76 | 248.3 | In-house | 15-265 (266) | Show / Hide |
Range on Protein: 316-575 Range on HMM: 15-265/266 Sequence Identity: 40% (100 aa) V-GTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQ .... . . | .|||. .. | .|| |....|. ..|||||||.|||..|. .| .|||.|.| ||| |.|||| ||| | ..| .. || ||| qkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaq YWPleKDSRIRFGFLTVTNLGVENMNHYKKTTLEIH----NTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSlavsnmgarskgQCPEPP | .. . .| ..|. .. ...| . .. .|.|...|.|. | | |||. |||... ....|. |...|| . |||||||||.|||||| ywp--deGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqq------------qsanhp IVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFA . || |.... . |.||..|.|.|.||. .|| ||| |.||..||. ivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlleyi |
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| Phosphatase | PTPN9.AA | Subfamily.RG.PD | 304-574 | 36 | 1.8e-75 | 245.0 | In-house | 3-262 (264) | Show / Hide |
Range on Protein: 304-574 Range on HMM: 3-262/264 Sequence Identity: 36% (99 aa) YEEYEDIRRENPVG-TFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTT |..|.| . .| . . |... | ||||. .. ....||||.. .|. ..||||||..|||.....|| |||||..| ||| |.||....||| | . eeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmlt RFEEGGRRKCGQYWPLEkDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQ--VTHFQFLSWPDYGVPSSAASLIDFlrVVRNqqslavsnmgA .| |||.. .||| . | .... |.|| | |....| ... ..||. .... |..... .||| |.|.|.. . | |... ... dldekgrrdedvyWPkk-deplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlif--vkke----------e RSKGQcPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF . . |||||.||| ||.||.. || | |||. . ||.|.. ..|..| . ..| |||.| |.|.||. aanke-eaGPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel |
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| Phosphatase | PTPN9.AA | Subfamily.R_Ecdysozoa.PD | 304-575 | 37 | 8.3e-75 | 242.6 | In-house | 3-268 (269) | Show / Hide |
Range on Protein: 304-575 Range on HMM: 3-268/269 Sequence Identity: 37% (102 aa) YEEYEDIRRE-NPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTT |||| . .. . . . | |. |||| |. |.|||||.| |. ..|||||||. |||.|. .| |.|.|.| ||||..||.| .||| . eeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmls RFEEGGRRkCGQYWPLEkdSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTE---ERQKRQVTHFQFLSWP-DYGVPSSAASLIDFLRVVRNQQSLAvSNM .| |. | .||| | ...| . |. |....| . .|.. ... . ..|.|. ... .|.|. || .| .|..... ||. ..| ...|.| nlteknrk-cakyWpie--devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelykln-kls GARSkgqcpepPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFA | ||||||||| ||.|.| .||. | ||.. ....|.|| .| ||.. .| ||| |.|.|.... gsrs-------PivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyraladys |
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| Phosphatase | PTPN9.AA | Subfamily.R_Anemone_1.PD | 306-574 | 37 | 9.3e-75 | 242.9 | In-house | 5-256 (258) | Show / Hide |
Range on Protein: 306-574 Range on HMM: 5-256/258 Sequence Identity: 37% (100 aa) EYEDIRrENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFE |.. .. |.. . ... . | .|||| |. ||..|| |.| |.. ..||||||.........|.| ||.|||.| ||| |||..|. |||| | .. efqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnli EGGRRKCGQYWPLekdSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQqslavSnmgarskgQ || .|| |||| | ..| |.|. |.. .| .|| .....|...|.|....|..||| |||.|.......| |... | .. egekkkchqYwPd---stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks-----s--------l CPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF . |.|||||||.||||.|. .| | |. . ....|..| ..|..|. .||||| |...|.|| agarpvvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavlea |
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| Phosphatase | PTPN9.AA | Subfamily.N3.PD | 304-573 | 38 | 9e-74 | 239.2 | In-house | 3-258 (261) | Show / Hide |
Range on Protein: 304-573 Range on HMM: 3-258/261 Sequence Identity: 38% (105 aa) YEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKrsghTQTDYINASFM----DGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIV ..| . |..| . ... | ||.|||| |. |.|||||.. ..||||||... .. .. | || |||||..| ||| ||||||. .||| laqfeelyrkkpglaisaarkpenlaknryrdilpydatrvklke----setdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstliv MTTRFEEGGRRKCGQYWPLeKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQslavsnmg | | || || |||| .. ...|| ..|. .. . | | ....|....|.....|.|.||| |||...|....|.. ||. . mlttlverGrvkChqyWPe-tedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr-------- arskgQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILE .. |.|.|||||||||||| . |...|| .|. ... . |..|| ||| .||..|| | .|||. -----sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailk |
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| Phosphatase | PTPN9.AA | Subfamily.N12.PD | 311-574 | 40 | 1.4e-70 | 228.8 | In-house | 17-268 (270) | Show / Hide |
Range on Protein: 311-574 Range on HMM: 17-268/270 Sequence Identity: 40% (101 aa) RRENPVGTfHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRR ..|. . | ... .. | .|||| |. |..||.|.| ... . |||||.|. | ..| .|| .|||| .| ||| |.||..| ..|| || |. || kaekvyst-eagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkk KCGQYWPLEKDSRIRFGFLTVTNLGVENMN-HYKKTTLEIHNTeeRQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSlavsnmgarskgqCPEP .||| |......|| ..||. .... . ||.... ...|.|. |.. .||| |||||| ||..... ||. |.. |.|||||||.||||| . kCeryWpeegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqe-------------seda PIVVHCSAGIGRTGTFCSLDICLAQLEELGT---LNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF ..|. .|.. . |.||. | ..|.||| .|| ||| . |||..|. PlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael |
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| Phosphatase | PTPN9.AA | Subfamily.N13.PD | 305-573 | 39 | 3.3e-70 | 227.8 | In-house | 4-256 (259) | Show / Hide |
Range on Protein: 305-573
Range on HMM: 4-256/259
Sequence Identity: 39% (108 aa)
EEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGhtqtdYINASFMDGY--KQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTT
||....| .|. | . . . | .|||| .| |.||||| . .| |||||.. ... || .|||| .| .|||.||||||.||.| |
eefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvt
RFEEGGRRKCGQYWPLEKDSRIRFGF-LTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSlavSNMgar
|.|. || .||| .|..... |.|..|.|.... .. .|.....| .. |.|.|..| .|||.|||||||.|. |.. ||. |. ..
lekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt---dag---
skgqcpepPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILE
||||||||||||.|.. ..|. | .| ..| ..| ..| || .|| .|| |.||||||
--------PivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile
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| Phosphatase | PTPN9.AA | Subfamily.N5_RR.PD | 322-575 | 34 | 1.8e-69 | 225.3 | In-house | 18-264 (265) | Show / Hide |
Range on Protein: 322-575 Range on HMM: 18-264/265 Sequence Identity: 34% (86 aa) SMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQ-TDYINASFMDGYKQ-KNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLE . .|. .|||| .. ...|| |...|.. . ..|||| .. ||.. ..||. ||||| || |||.|.....| ||||.|...| |.|| .|.| .. levfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPda KDSRI--RFGFLTVTNLGVENMNHYKKTTLEIHNTEErQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGarskgqcpepPIVVHCSA | .| |.| . ... .. . |.|. ..| ....|. .|.|.|. . .||| .| .. .|.|... |..... . ...|.|||||||||||| | . edyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenakla----------Pvvvhcsa GIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFA .|.. ||.| ....|...|...| .| .|| ||| . ..|. ... GiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl |
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| Phosphatase | PTPN9.AA | Subfamily.N_Choan_2.PD | 329-575 | 36 | 9.6e-69 | 222.7 | In-house | 23-265 (266) | Show / Hide |
Range on Protein: 329-575 Range on HMM: 23-265/266 Sequence Identity: 36% (91 aa) EKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQ-KNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRF- . ||| |. .|||.| . . .| |||| .. |... |..|| ..|||..| ..|| |.||.|| ||||| .|| ||.|| .||| |....... rlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkla -GFLTVTNLGVENMNHYKKTTLEIHNteERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKgqcpEpPIVVHCSAGIGRTGTF |...|..| |... | .| |.... . ..|...||.. .||| |||... | .. ... . . ... . | |..||||||.|||||. . dgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldka----e-PllvHcsaGvgRtGtl CSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFA ||.. ||| . ..| . ....| .| .|.|||| . |||..|.| iaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya |
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| Phosphatase | PTPN9.AA | Subfamily.N14.PD | 303-574 | 35 | 1.8e-68 | 221.9 | In-house | 2-273 (275) | Show / Hide |
Range on Protein: 303-574 Range on HMM: 2-273/275 Sequence Identity: 35% (98 aa) IYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKrSGHTQTDYINASFMDG--YKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVM .. ||| | ... ...... | | ||||. || ...||.|. . ...|.||||| . .. || .|||||.| .||| |||||.| .||| vfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsp-tkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivm TTRFEEGGRRKCGQYWPLE--KDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVrnqQSLAVSNM |. ||.|. |. .|.| . | ....|| ||. .|. . . |.|... ...|.| |.|. ||| |||. ....||. | ||. lteeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeev---qsvrrktn GARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF .. .. .||..||||||.|||| |. .| ||. .... ....|.|.|| . .|| || | ||..... sevesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvliky |
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| Phosphatase | PTPN9.AA | Subfamily.RK.PD | 304-574 | 36 | 2.7e-68 | 221.3 | In-house | 3-265 (267) | Show / Hide |
Range on Protein: 304-574
Range on HMM: 3-265/267
Sequence Identity: 36% (99 aa)
YEEYEDI---RRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHtQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVM
||.| . | . . .. . | ||||..|. .|...|.|. | ..|||||...|.||. .|.| |||||..| .||| .|....||| | .
keefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivm
TTRF-EEGGRRKCGQYWPleKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHN--TEERQKRQVTHFQFLSWPDY-GVPSSAASLIDFLRVVRNQQSLavs
| || || .||| .|...|.| . |. . .| . . . .. ... ..|.| .||||.||.| .|| |. ||....| | ..|.
lteldvevgrvkClkyWP--edtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee---
nmgarskgqCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF
| .|||||.|| ||.|||. .|| | .|. |...||..| .|.... ..| ||| |.| .|||.
---------eeeGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvilea
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| Phosphatase | PTPN9.AA | Subfamily.N23.PD | 340-575 | 35 | 1.3e-64 | 209.7 | In-house | 115-349 (350) | Show / Hide |
Range on Protein: 340-575 Range on HMM: 115-349/350 Sequence Identity: 35% (84 aa) DQTRVKLTKRSG-HTQTDYINASFMDGYKQ-KNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVE |..|||| . .. .| |||||... .| ||||...| |||||||||.. |||| |. .||.. || |||| ... || |.|. .. dpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslr NMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQsLAVSNMGARSKgqcPEPPIVVHCSAGIGRTGTFCSLDICLAQLE- . ... . .|... .. ...|.|.|... .|...|||.| .|..|| .|.. .. . .. .. ||..|||||.||||||| . ...|. ssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetay-aqqrktetege---ggkPiilhCsaGvgRtgtfcvvysairelta ELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFA . | .|. . |.|.| || ...|. ... ..|.|.||.| gngiiniprvvrrlrqqRkymvqkkvilkklyeavleaa |
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| Phosphatase | PTPN9.AA | Subfamily.N1.PD | 310-573 | 36 | 2.6e-61 | 198.7 | In-house | 9-265 (268) | Show / Hide |
Range on Protein: 310-573 Range on HMM: 9-265/268 Sequence Identity: 36% (99 aa) IRRENPVGTF--HCSMSPGNLEKNRYGDVPCLDQTRVKLTKrsghTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEG |..| . . . | | ..||| || | .|.|| . ...||||||... . | || ||||| .| || |||||. ..|.. | .. idkeskekeletreaklpenrglnryrdvspydhsrikler----advdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEk GRRKCGQYWPLEKDS-RIRFGF--LTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAvSNMGarskg || |||| |... . . |.|. . |. ... . .||... |... |...||.. |||.|||.| |....|| ||. ||. |..| nqikCaqywpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLs-sdvg----- qcpepPIVVHCSAGIGRTGTFCSLDICLAQLEELGT---LNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILE |.|.||||||||.||.. .| ||...|. | ... . . .| .| ||||.| | | |||| -----pavihCsagigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile |
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| Phosphatase | PTPN9.AA | Subfamily.RC.PD | 306-574 | 31 | 1.6e-60 | 196.1 | In-house | 5-286 (288) | Show / Hide |
Range on Protein: 306-574 Range on HMM: 5-286/288 Sequence Identity: 31% (90 aa) EYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKL------TK-------------RSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDF |.. . . | . . . | .|||| || | ||.| .| .. ..||||||.|.||. . || .||||..| || efqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddf WLMVWEQKVLVIVMTTRFEEGGRRKCGQYWpleKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRV | |..|.|| |||| |. .|| | || .|| .. . .| . | .. . | ||. | ... |.||..|. ||.. ..||.....||... wrmiferkvkvivmltelkeGdrekcaeyw---eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqv VRNQqsLAVSNMGArSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF | . . . |..|||..| .|||.|..|. | || ..||| | ..| .|. ... ||| . |... |. vkqk--lpqkrsse-afknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet |
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| Phosphatase | PTPN9.AA | Subfamily.N_Nematode_1.PD | 304-574 | 32 | 8.3e-58 | 187.0 | In-house | 3-263 (265) | Show / Hide |
Range on Protein: 304-574
Range on HMM: 3-263/265
Sequence Identity: 32% (90 aa)
YEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSghTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTR
.|...... |. . . . . .|||| ||.|||..||||.. . . .||| | .. . . .| .|.||..| ||||| .|| ||| ..
rdefralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeep--lpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlck
FEEGGRRKCGQYWPLEKDSRIRFGFL----TV-TNLGVENMNHYKK----TTLEIHNTEeRQKRQVTHFQFLSWPDYGVPSSAASLIdflrvvrnqqsla
| |..|| .|.|....... | || ..|||..... .. |.||.. . ...|.|||.|. ||| |||. . .
liekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaG-ektrkvthyqWtdWPdrGvPpadlaal-------------
vsnmGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLN-VFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF
.. . . ||||||||||||||| ... | .| | ... . .| ..| ||..|||| || | .. .|..
----elleavrgskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllny
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| Phosphatase | PTPN9.AA | Subfamily.R_Nematode_2.PD | 327-568 | 36 | 3.4e-55 | 178.4 | In-house | 29-253 (261) | Show / Hide |
Range on Protein: 327-568 Range on HMM: 29-253/261 Sequence Identity: 36% (82 aa) NLEKNRYGDVPCLDQTRVKLTKRsGhTQTDyINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRF . .|.|| |||| ..|.|. | .... | | ... .... .| |||||||| ||| || .|| ||| ... | ..|| .|.|||. ..... pkdkhRypdvPCkpetavevivd-g-krvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldl GFLTVTNLGVENMNH--YKKTTLEIHNTEE-RQKRQVTHFQFLSWPDYGVPSSAASLIdflrvvrnqqslavS--NMGARSkgqcpEPPIVVHCSAGIGR | ........|.. . .|.||...... . | |||.|. .|||.||| | | |.. .| | |||||||||||||..| . . ..|. grfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelf--------------eLlelvkks-----ekPivvhCsaGiGR TGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCY |... ... .| .| .||| .|.|. tmafigteylareveadptieltealkelrehRwkgiqtesqlywlt |
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| Phosphatase | PTPN9.AA | Subfamily.RN.PD | 318-573 | 39 | 1e-52 | 170.3 | In-house | 18-261 (264) | Show / Hide |
Range on Protein: 318-573 Range on HMM: 18-261/264 Sequence Identity: 39% (102 aa) TFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASF-MDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYW | . . .. |..|||. .| |..||||.... ....||||||. .| .. ||| ||||| .| ||| ||||| | |||. || || | ..| .|| tkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckryw PLEKDSrIrFGFLTVtNLGVEN--MNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNqqslavSNMGaRSkgqCpepPIVVH | | . . ... | .| | . | .. . | . .. | || | |||||. |||.|| ||..| | | | | ||| |||||||. pdeGse-v-yhiyev-hlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnk------syrG-rs---c---pivvh CSAGIGRTGTFCSLDICLAQLEE-LGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILE | ||||... .|. |..| . ... |. .| ||. ..| .|. |...|. | csdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae |
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| Phosphatase | PTPN9.AA | Subfamily.N_Nematode_4.PD | 320-573 | 33 | 4.8e-52 | 168.2 | In-house | 19-261 (264) | Show / Hide |
Range on Protein: 320-573 Range on HMM: 19-261/264 Sequence Identity: 33% (86 aa) HCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSghTQTDYINASFMDGYkQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLE |.| | .|||| |. | |.||| | .|. . ||| ||.| | || |||||..| ||| ||...|. |.||..|.| .|| .|.| ... tasaseknsdknryadilcidetrvvlknrd--pdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypek KDSRIRFGFLTVTNLGVENM--NHYKKTTLEIHNTEERQ-----KRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSlavsnmgarskgqcpEPPIV .|| .| . ... .|.. |||... . | |.|. |.| | ||..|.....|..... | |||||||| sekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkk---------------ekPiv VHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILE |.||| |. .|.. .. | . ..| . | ..|. | ..|. |.| . ..| vhcsaGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvlie |
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| Phosphatase | PTPN9.AA | Subfamily.N20.PD | 304-574 | 37 | 1.9e-49 | 159.8 | In-house | 3-255 (257) | Show / Hide |
Range on Protein: 304-574 Range on HMM: 3-255/257 Sequence Identity: 37% (99 aa) YEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKrsghtQTDYINASFMDGY--KQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMT .|. . .| | | . | | ||||| |. | ||| | | ||||||.. .. || ||||| .| ||| || |..|| | || mqefmalelknlpgefnsgnqpsnreknryrdilpydstrvplgk-----skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviami TRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQsLAvsnmGar ||| || .|||. . . .. | . .... ... . . | ..|| |||.| |.|| |.| ..||. . |. | treieggiikcyhywpislkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarksh-lt----g-- skgqcpepPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF |.|||||||||||| | .|. .. . . ..|... |..|| ||. .|| |||.||| .|| --------pmvvhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlev |
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| Phosphatase | PTPN9.AA | PTPc_motif | 459-573 | 41 | 3.7e-47 | 163.9 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 459-573 Range on HMM: 1-92/92 Sequence Identity: 41% (50 aa) QVTHFQFLSWPDY-----GVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQ .|.|.....||| |||. |...|.| ||. |||||||||.|||||||..|... | ...|||| .||.| TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK--------------------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQ RAFSIQTPEQYYFCYKAILE |....|| ||| |||..||| RPGMVQTEEQYIFCYRCILE |
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| Phosphatase | PTPN9.AA | Subfamily.N_Nematode_6.PD | 305-574 | 28 | 7.3e-45 | 144.6 | In-house | 4-251 (253) | Show / Hide |
Range on Protein: 305-574
Range on HMM: 4-251/253
Sequence Identity: 28% (76 aa)
EEYEDIRreNPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRsghtQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRF
||.| | . . ... .. ..||| ...| |..|.||. . || |.... .... .| ||.|||.| .|||. . | ||| . |
keykdsp--neaseseataflkfkdrnrytniqCcdagrlkladd----edfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcel
EEGGRRKCGQYWPLEKDSRIRFG-FLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSlavsnmgarsk
|. |. .| . . ... . ||...| .... . .| . .. | |... .|||.||| | | . .| ||....
vekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk-----------
gqcpepPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF
|||||||||.|||||. . | |. | .| . . ..| .|...|| || . .. .||.
------PivvhCsaGvGrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvley
|
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| Phosphatase | PTPN9.AA | Subfamily.R_Nematode_3.PD | 326-574 | 25 | 1.8e-42 | 136.8 | In-house | 22-265 (267) | Show / Hide |
Range on Protein: 326-574 Range on HMM: 22-265/267 Sequence Identity: 25% (66 aa) GNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDgYKQKNAYIGTQGPL--------ENTYRDFWLMVWEQKVLVIVMTTRFEE---GGRRKCGQ .....|. .||.| .|||.| . . . |.|.|... .... | ||.|. ..| || |. ..|| ..||.| | .. .|| .|.| kkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcse YWPLEKDSRIRFGFLTV--TNLGVENMNHYKKTTLEIhNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSlavsnmgarskgqcpepPIV ...| ..|. ..| |. | . .| ||.. . |.... .||| .. .|.. ..| .. .... ...|.. .. |.|||| Yypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfvekskt-----------------pvv VHCSAGIGRTGTFCSLDICLAQ-LEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF |.||.|..|. . .. ... |.|.. . .. .| ||| |||.... | ||.. VHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkl |
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| Phosphatase | PTPN9.AA | Subfamily.N_Nematode_5.PD | 305-574 | 26 | 2.2e-42 | 136.3 | In-house | 4-256 (258) | Show / Hide |
Range on Protein: 305-574
Range on HMM: 4-256/258
Sequence Identity: 26% (73 aa)
EEYEDIRRENPVGTfHCSMSPGNLEKNRYGDVPCLDQTRVkltkRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRF
.|.|.. | .|.. ||.|||. ||..||.||| . .. . .||||| .. . .. .| || || .| .||||| ..|. .|. .. |
tefeklaslkpnke-tckafeknlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllved
EEGGRRKCgQYWPLEKDSRIRFGFLTVTNLGVENMNHY-KKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDflrvvR----NQQSLAVSNmg
| .... ...|||... .| ....| ||.... |. |.|. . .. ... .. |..||.. . .| | .. ..|
eelketav-sffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik-----raiekvlskkqgkn--
arskgqcpePPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF
.|.||....|.||.||| |.. ||.. ..|. ... .|.||. .... || . |.|.|..
---------apvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldy
|
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| Phosphatase | PTPN9.AA | Subfamily.N_Nematode_egg.PD | 315-575 | 29 | 2e-37 | 120.3 | In-house | 14-256 (257) | Show / Hide |
Range on Protein: 315-575 Range on HMM: 14-256/257 Sequence Identity: 29% (75 aa) PVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGgrRKCGQ ... ..| .||| | |.| . .|||| | | |.| | ...| | .| .| || || ||| ||...||||| | | .| ||| deislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--ercey YWPLEKDSRIRF--GFLTVTNLGVENMN--HYKKTTLEIhNTEERQKRQVTHFQFlswpDYGVPSSAASLIDFLRVVRNQqslavSNmgarskgqcpepP .. ... | | ..||.|.. .. | | . ..... . |.| |.| | . || .|| |. |.||.. | ywpkaeseslvtvpGslrienlkvdskadplfrvtklkl-vGgddeelflehwqg----dvnylsdvysplrvlrklrnl-----sk------------p IVVHCSAGIGRTGTFCSLDICLAQLEEL--GTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFA . ...|. ...| | .| | ..| .| .|.|.... .| | |. .| | vvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlffi |
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| Phosphatase | PTPN9.AA | Subfamily.N_Nematode_eak.PD | 315-574 | 22 | 2.9e-22 | 70.5 | In-house | 14-279 (281) | Show / Hide |
Range on Protein: 315-574 Range on HMM: 14-279/281 Sequence Identity: 22% (59 aa) PVGTFHCSMSPGNLEKNR-YGDVPcLDQTRVKLTKrSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCG .. . . . ....|| .. || |. |.|| | . ||||| .. . . || | . |. || || |||||. | . | .|. rllsirvtarleavnrnrvvkivp-qdrylvrlts-sqlnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksd QYWPLEKdSRIRFGFLTVTNLGV-ENMNHYKKTTLEIHNTEErqKRQVTHFQFLSWPDYGVPSSAaSLIDFLRVVRNQQSLAVSNMGAR---S--K---G | . ...|.| |. . | .. |... .| .| |... | .. .|.. . .|... | . .| . | | | . kyfpdkt-evlkyGildverkeyavkrniletrllilrkGne--thrvlhykvfGwtettlpkye-dflalrkvmkevGvlllivmksallrstlkkyih QCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEEL--GTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF . .. | |.|.| .|. . ... . | . ......| |. . |. | |...|.. tppsfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldy |
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| Phosphatase | PTPN9.AA | Subfamily.N_Fungi_PTP1.PD | 328-439 | 26 | 3.3e-20 | 63.6 | In-house | 46-173 (343) | Show / Hide |
Range on Protein: 328-439 Range on HMM: 46-173/343 Sequence Identity: 26% (34 aa) LEKNRYGDVPCLDQTRVKLT--------KRSGHTQTDYINASFMDGY----KQKNA--YIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCG |||| .. ...|||| |. . |||||... ... || ||.|| .|. ||. .. . || ||.. | | ...|| .| faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy QYWPLEKDS--RIRFGFLTVTNLGVENM |. . . ... |.... rYWqegsydditvklaskwenimginds |
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| Phosphatase | PTPN9.AA | Subfamily.N_Fungi_PTP1.PD | 457-574 | 27 | 2.7e-18 | 57.3 | In-house | 212-341 (343) | Show / Hide |
Range on Protein: 457-574 Range on HMM: 212-341/343 Sequence Identity: 27% (36 aa) KRQVTHFQFLSWPDYGVPSSAASLIDFLRvvrNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTL--------------- .| ..|. |.| .. |.. | .. | ... . .||.||||||.|||||...|| | ..| | .| . pyevyqlqvknWkDlslllnPesilqale---vkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrD NVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEF ...| ..| || .|. .|. |.|.|.| . lisiivnelrkqrismvqnldqfifiYeallfy |
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| Phosphatase | PTPN9.AA | Subfamily.PTPDC1.PD | 452-567 | 28 | 2e-09 | 28.5 | In-house | 127-220 (229) | Show / Hide |
Range on Protein: 452-567 Range on HMM: 127-220/229 Sequence Identity: 28% (33 aa) TEERQKRQVTHFQFlSWPDYGVPSSaASLIDFLRVVRNqqslAVSNmGArskgqcpeppIVVHCSAGIGRTGTFCSLDICLAQleelgTLNVFQTVSRMR || .........| ...||||.| ...| .|| |... |. | ||| || |||| . . |. |. . .. .| peelmrqgiyfynf-glkDygvasl-eriLdivkvvdf----alee-gk----------iavHCHAGlGRtGvliacylvyak-----rltaeeaiklvr TQRAFSIQTPEQYYFC .|. |||| || .. skrpksiqtreqvelv |
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| Phosphatase | PTPN9.AA | Family.DSP.PD | 429-528 | 15 | 5.7e-09 | 27.0 | In-house | 140-205 (387) | Show / Hide |
Range on Protein: 429-528 Range on HMM: 140-205/387 Sequence Identity: 15% (12 aa) LtvtnlgvenmnhykkttleihnT---EERQKRQVTHFQFlSWPDYGVPSSAASLIDFLRVVRNqqslavsnmgarskGQCPEPPIVVHCSAGIGRTGTF . .. .. .... .. ...|...|. . .. ..... . |.... ..||| ||.||.|| .. t----------------------ddkpqftkelgikylri-pidDhnapplenlfekaidfiee--------------gndskgvVlVHCkaGkgRsgtl CSL iia |
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| Phosphatase | PTPN9.AA | Subfamily.DSP23.PD | 508-564 | 35 | 4e-06 | 18.2 | In-house | 66-117 (128) | Show / Hide |
Range on Protein: 508-564 Range on HMM: 66-117/128 Sequence Identity: 35% (20 aa) EPPIVVHCSAGIGRTGTFCSldICLAQLEElgtLNVFQTVSRMRTQRAFSIQTPEQY | .. ||| |.|||||. . | . |. | ... .| .| ||.| || eeavgvhcalGlGrtGtlla--cylvkeeg---laaddaiaevrkrrkGsietveqe |
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