PTPRA
Species: Human
Alias: RPTPA, PTPRA, PTPA, HPTPalpha, PTPRL2, LRP, HLPR, R-PTP-alpha, HEPTP, HPTPA
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RA
Protein domain

Protein domains of PTPRA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase PTPRA.AA Subfamily.N6.PD 239-499 41 1.2e-77 252.9 In-house 12-291 (295) Show / Hide
Range on Protein: 239-499
Range on HMM: 12-291/295
Sequence Identity: 41% (116 aa)

KLFREEFNALP--ACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPV-EGVPDSDYINASFI--------NGYQEK-----NKFIAAQGPKEETVN
| |||. |   ..  . ... ..| |||||||| ||||.||.|| |. . . ||.||||||..|        .| . .     ...||.||...||.|||
lgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvs

DFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCW-TYGNIRVSVEDVTVLVDYTVRKFCIQQVgdmTNRKPQRLITQFHFTSWPDFGVPFTPIGML
||.|..|.  |||.|.  || . |||.||||..   ..|.|.|.  . .   |||.|.| ...     . |..| | |.||..||| |||  |  .|.||
dFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshk---dkdkeareifqyhfkaWPdhgvpkdpgvvl

KFLKKVKACNPQY--AGAIVVHCSAGVGRTGTFVVIDAMLDMMHT---ERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALL
..|.. . .   ||.||||||||.||||||.|||..|.....   . ..|..  . ..|.|| ..|||..|| |.|.|.    
nfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq

Phosphatase PTPRA.AA Subfamily.RA.PD 241-503 64 9.40000000001e-154 502.2 In-house 2-266 (266) Show / Hide
Range on Protein: 241-503
Range on HMM: 2-266/266
Sequence Identity: 64% (170 aa)

FREEFNALPACPIQ-ATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMV
..|||..|....|| .....|.|||||.|||.|.|||||.|||.|. .||...|||||||||.||.||.|||||||||||||.|||||||||..|||||.
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativml

TNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAG-AI
|.||||||.||||||||.|..|||.|||.|.|.|||.|||||.|...|..|.|..|..||..||||||||..|||....||||.|||||....|.|. .|
telkerkeekcaqywpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpi

VVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL
||||||||||||||.|.||.|.....|||.||...|.|.|.||.|||||..||.|||..|||...
vvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlleyid

Phosphatase PTPRA.AA PTPc 240-503 36 1.7e-133 450.72 SMART 1-308 (308) Show / Hide
Range on Protein: 240-503
Range on HMM: 1-308/308
Sequence Identity: 36% (115 aa)

LFREEFNALPACPIQA---------TCEAASKEENK--EKNRYV-NILPYDHSRVHLTPVEGV----PDSDYINASFINGYQEKNKFIAAQGPKEETVND
 |.|||. |..  ..          .|. | ..||.  .||||  .|..|||.||.|.| .|     ..||||||..|.|| .....|..|||...|..|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMIWEQNTATIVMVTNLKER--------KECKCAQYWPDQGCWTYGNIRVSVEDVTVLV-DYTVRKFCIQQVGD-----MTNRKPQRLITQFHFTSWP
||||.|.|....||| .|. |.        .  ||.|||||  ..|||.|.|  ......  |||.|.|...  |.     |   .  | .|..|.|.||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSM-ACSETRTVTHYHYTNWP

DFGVPFTPIGMLKFLKKVKACNPQY-------------------AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQ
|.||| .| ..|.|...|.......                   .| ||||||||.||||||..||.|......   ||... |...| ||..||||..|
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQ

YVFIYQALLEHYL
|.|.|...|| ..
YIFCYRCILEYIK

Phosphatase PTPRA.AA Y_phosphatase 265-500 46 1.5e-129 441.49 Pfam 1-243 (243) Show / Hide
Range on Protein: 265-500
Range on HMM: 1-243/243
Sequence Identity: 46% (115 aa)

NKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFING-YQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKE-CK-CAQYWPD---QG
|||||||..|..|||.||.|.|..| .|||||||..|.| |......|..|||...|..|||||.|.|....|||..|. |..   | |.|||||   ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

CWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFT-PIGMLKFLKKVKACNP-QYAG--AIVVHCSAGVGRTGTFVV
..|||...| ....... |||||.| ..  ||   ... | .|..|.|.|||.||| . | .||.|...|. ..| . .|   ||||||||.||||||..
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQ--KQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCA

IDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE
||.|...|..| .||....|...|.||..||||..||.|.||..||
IDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase PTPRA.AA Subfamily.R_Anemone_2.PD 241-501 45 5.2e-103 336.0 In-house 2-260 (262) Show / Hide
Range on Protein: 241-501
Range on HMM: 2-260/262
Sequence Identity: 45% (118 aa)

FREEFNALPACPIQ-ATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMV
. ||...|  .. .  |...| .. || ||||.|||.||..||.|...||...||||||..|.||..|...||.|.|  ||..|||||.||||.|.|||.
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGdmtnRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACN-PQYAGAI
|...||   |...|||..|  .||...| ... . | ||..|.| ... .     . .| . |||.||||| |||  . ..|.....|.. . .. ||.|
tqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkrte----eeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpi

VVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
||||||||||||.|...|..|. .. |  |||...|...| ||  ||||. ||.|||..||| 
vvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvllea

Phosphatase PTPRA.AA Subfamily.R_Anemone_1.PD 242-501 45 7.8e-97 315.8 In-house 3-256 (258) Show / Hide
Range on Protein: 242-501
Range on HMM: 3-256/258
Sequence Identity: 45% (118 aa)

REEFNALPACPiQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN
..||. |   . . . |.|.|.|||.|||| .|...||||| |. ... ..|||||||..........|||.|.| ||||.|||||.|......|||.||
aaefqrlkeik-eeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtn

LKERKECKCAQYWPDqGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMtnrkPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVH
|.| .. || ||||| .  .||..|||..   |  ||..|.. .....       .| ..|.|||.|||||| .   .|....||.. . . | ..||||
liegekkkchqYwPd-stekygelrvslrkkevfadyiirtlvlskkket----eerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvh

CSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
||||||||.|.||||||. ...|. ||..  | .|| .|..||||  |||||..|.||  
CsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavlea

Phosphatase PTPRA.AA Subfamily.RG.PD 241-501 42 1.3e-94 308.3 In-house 2-262 (264) Show / Hide
Range on Protein: 241-501
Range on HMM: 2-262/264
Sequence Identity: 42% (112 aa)

FREEFNALPACPIQA-TCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMV
. |.|...  .  .  ..|...|||||||||..||.....|||.|.|. |. ..||||||.|.||. ....|..||| .||..||||||||.|...|||.
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

TNLKERKECKCAQYWPD-QGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKpqRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAI
|.|.|.   ....|||. ..  ......| . . ..| .||||.| ...  | ....  | ..|.|.|.||| |.|   . .| | ||.|.|.. || ||
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkeke--rvvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPi

VVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
||.||||||.||....|..|  ...| .|.||... .|||.| ..|.|  ||||||.||||  
vvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel

Phosphatase PTPRA.AA Subfamily.RB.PD 241-500 43 3.4e-94 306.9 In-house 2-258 (261) Show / Hide
Range on Protein: 241-500
Range on HMM: 2-258/261
Sequence Identity: 43% (113 aa)

FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVT
|.||.. | ..  . ...||....|..|||. ||||||||||.|. ..  .|.|||||..|.||. ....||.||| .|||.|||||.||....|||.|.
fseeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

NLKERKECKCAQYWPDQG-CWTYGNIRVSVEDVTVLVDYTVRKFCIQQvGDMtnrkpQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQY--AGA
| |.   || .|||..    .||.|.|..   . | ....|.| |.. |.      .| ..|.|||||||.||| ..  .|.|...|.    .   .. |
qlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiek-gke-----krkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkP

IVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE
||||||||||||||. .| .|. ....  |||.|.|...| .|...|||  ||.||...||. 
ivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclld

Phosphatase PTPRA.AA Subfamily.R_Sponge_2.PD 253-501 43 2e-92 301.2 In-house 13-260 (262) Show / Hide
Range on Protein: 253-501
Range on HMM: 13-260/262
Sequence Identity: 43% (108 aa)

IQATCEAASKEENKEKNRYVNILPYDHSRVHLTPvEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQ
. ....| ..||. |||...|||||.|||.|.. .|..|||||||||..||.... .||.||| .|||.|||||.||... ||||.|||.|... |||.|
tefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcak

YWPDQ--GCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDmtnRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV-KACNPQYAGAIVVHCSAGVGRT
||..  .  .||...| ... . |.||..||. ...      .. .. .|||||..||. .|| .   .|...|.| .| . .  .||.|.||.||||||
YWPekvdeeveygkfkvtlkeeekladyiirklklskeks---segeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrt

GTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
||...|..|. ...|...||. ..  .| .| ..||.  |||||..||||  
GtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalley

Phosphatase PTPRA.AA Subfamily.RK.PD 241-501 39 8.5e-92 298.9 In-house 2-265 (267) Show / Hide
Range on Protein: 241-501
Range on HMM: 2-265/267
Sequence Identity: 39% (106 aa)

FREEFNALPA--CPI-QATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVpDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIV
..|||..| .    . .. |..| |..|.||||. .||.||.|.| |..|.|  .||||||..|..|.  ..||..|||..|||.||||.....|.|.||
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

MVTNL-KERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTnrKPQRLITQFHFTSWPDF-GVPFTPIGMLKFLKKVKACNPQ-Y
|.|.| .|.   || .|||...  .||.|.| . ..... |. || | ....      . .|.. ||.|..||.. .||    ..||....||. ...  
mlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargq--eeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeee

AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
.| |||||.|| ||.|||..|| .|.|...|. |||.  |  .|...  ||.|  ||.|.|.. || 
eGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvilea

Phosphatase PTPRA.AA Subfamily.R_Ecdysozoa.PD 241-501 42 8.9e-89 289.0 In-house 2-267 (269) Show / Hide
Range on Protein: 241-501
Range on HMM: 2-267/269
Sequence Identity: 42% (111 aa)

FREEFNALPAC-PIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMV
. ||.. |.|   |. ..... |.||. |||| .| ..|. || |....|  ||||||||||.||.||.||||||.| |.|..||||||.||.  .|||.
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml

TNLKERKECkCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTnRKPQRLITQFHFTSWP-DFGVPFTPIGMLKFLKKVKACNPQY----
.||.| ..  ||.|||..    ||.| | . .     ||. |.. . .... .  . .| ..|...|.|.|. || .. |.||....|.  . .      
snlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskkkees-vedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsg

-AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
 . |||||||||||.|.|| .| .|. ...| |||.. .|  .| ||  .||||||.|.||...    
srsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralady

Phosphatase PTPRA.AA Subfamily.N_Choan_1.PD 241-500 38 1.8e-81 265.2 In-house 2-259 (262) Show / Hide
Range on Protein: 241-500
Range on HMM: 2-259/262
Sequence Identity: 38% (102 aa)

FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVT
| ||...| .  .. |..|. ..||..||||.||  ||..||..|| |   ..|||||.|..||......||.|||  .....||.|.|||.  .|||||
fieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvt

NLKERKECKCAQYWPDQG-CWTYGNIRVSVEDVTVLVDYTVRKFCIQQvgdmtNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV-KACNPQYAGAI
.  |  . || .||||.    ..|...|. .  .    |  ||| ...     .   .| ..|...|.||| ||| |.  .|.| |.| || ...   ..
reieagklkChryWPdenselklgdvtvkslseeekktyierkfkler-----esgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkapl

VVHCSAGVGRTGTFVVIDAMLDMMHTERKV-DVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE
|.|||||||||||.. .| ... ....... ||   |. .| .|  |||| .|| |.|.|.|.
vihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavld

Phosphatase PTPRA.AA Subfamily.RC.PD 241-502 37 1e-79 259.6 In-house 2-287 (288) Show / Hide
Range on Protein: 241-502
Range on HMM: 2-287/288
Sequence Identity: 37% (108 aa)

FREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHL-------------------TPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETV
.  ||. ||    . | . | |||||.||||...||||. ||.|                     ...   |.|||||||..|.. .|.||||||..|||
leaefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketv

NDFWRMIWEQNTATIVMVTNLKERKECKCAQYWpDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQvgdmTNRKPQRLITQFHFTSWPDFGVPFTPIGML
.||||||.|. .  |||.|.||| .. |||.|| ..|  .||.. | ..|     ||..||. ...      ||  | .||. .|||.. ..|  |  .|
ddfwrmiferkvkvivmltelkeGdrekcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvn----kkrkdsrevtqiqytswsveqlpeepkell

KFL----------KKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY
|..          ....| .  ... ..|||..|..|||.|. ..|.|. . .| ||||...| ..| .|. ||..  ||...|..| | |
kliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvety

Phosphatase PTPRA.AA Subfamily.N9.PD 242-501 40 2.2e-79 258.6 In-house 3-273 (275) Show / Hide
Range on Protein: 242-501
Range on HMM: 3-273/275
Sequence Identity: 40% (112 aa)

REEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN
..|. .. . |.. | .|. .  | ||||| ..| ||..||.|. ... . ||||||.|..||..|. |||.||| ..||.|||||.|||.. .|||.| 
skeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttr

LKERKECKCAQYWP--DQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVgdmtNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACN---PQYA-
. ||.  ||.||||  .. .  .|...||. .| |  ||.||.. |..|    . . .| .| | |.||||.||| .   .|..|.||.       ..  
vvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknv----kteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelg

---------GAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
           ||||||||.||||||. .|  |. .... .|||   |...|.||  ..||. ||.| |.|.||.
deskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley

Phosphatase PTPRA.AA Subfamily.N12.PD 257-500 41 9.8e-77 249.5 In-house 24-267 (270) Show / Hide
Range on Protein: 257-500
Range on HMM: 24-267/270
Sequence Identity: 41% (104 aa)

CEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD
||..||||..|||| .|||||.|||.|.  |....||||||.||.| ..| ..||||||  .|..||||||||.|.  .||. .. | .  ||..|||..
teagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpe

QG--CWTYGNIRVSVEDVTVLV-DYTVRKFCIQQVgdmtnrKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFV
|    ..|...|..|.   .  |...| . ...       | .| ..|||.|.||| ||| ..  .|.....|.  . . .  .||||||||||||| ..
egeeelefgefevtleeekavdddflirtLkveaq------kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtii

VIDAMLDMMHTERK---VDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE
|| . .....|.    .||.  | ..| ||  .|||  ||...|.|..| 
aidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae

Phosphatase PTPRA.AA Subfamily.N13.PD 243-500 39 2.4e-73 238.7 In-house 4-256 (259) Show / Hide
Range on Protein: 243-500
Range on HMM: 4-256/259
Sequence Identity: 39% (104 aa)

EEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGvpdsdYINASFINGYQEKNK--FIAAQGPKEETVNDFWRMIWEQNTATIVMVT
|||. |     . ||| . |.|||.|||| |.||||..||.|    |     |||||.|.   ....  .||.|||  |||.|||.|.|||..|.|||. 
eefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvt

NLKERKECKCAQYWPDQG---CWTYGNIRVSVEDVTVLVDYTVRKFCIQqvgDMTNRKpQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPqYAGA
||... || .|||..       .. ..|....|. | ...||.. ..   |.  ..  | .....|..||| ||| ... ...|...|.  .   || ||
lekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavk---dsesge-srevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagP

IVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE
||||||.||.|....||..|.... ....||   | ..| ||  .|||. ||.|.|.|.||  
ivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile

Phosphatase PTPRA.AA Subfamily.N5_RR.PD 244-501 36 2.4e-72 235.3 In-house 5-263 (265) Show / Hide
Range on Protein: 244-501
Range on HMM: 5-263/265
Sequence Identity: 36% (96 aa)

EFNALPACPiqaTCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGV-PDSDYINASFINGYQEKNK-FIAAQGPKEETVNDFWRMIWEQNTATIVMVTN
||  ||.     . |  .   ...|||| .||| ..||| |.. ..  .||.|||| .| ||.|..| ..|.|||  .|..||||||.....  |||.|.
eflelPlnf---sqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltk

LKERKECKCAQYWPDQGCW----TYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRkpqrlITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYA--
|||... |||.|.||.       .||.. . ||...   ||.|||. .... .....     .. . .|.|||  .|  ..|.....|.  . . .   .
lkeanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkylervers-----vkhywytdWPdhksPddintlldlvleveesreeenak

-GAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
 .|||||||.|||| |. |.  .  .. | .||| . |...| .|  ||||. || .|..|| ..  
laPvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcly

Phosphatase PTPRA.AA Subfamily.N6.PD 526-792 36 9e-71 230.4 In-house 7-294 (295) Show / Hide
Range on Protein: 526-792
Range on HMM: 7-294/295
Sequence Identity: 36% (105 aa)

PGTSNNGLEEEFKKLTSIKIQNDK-MRTGNLPANMKKNRVLQIIPYEFNRVIIP-VKRGEENTDYVNASFI--------DGYRQK-----DSYIASQGPL
| .   |..|||..|.  . .. .  . |. . | .|||. .|.|.. .|||.  ...    .||.||..|        .|  ..      .|||.||.|
pksqtlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcL

LHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGL-VSYGDITVELKKEEECESYTVRDLLVTNT-RENKSRQIRQFHFHGWPEVGIPSDGKG
 .|..|||||.|. .|  |||.|.  |||..|||.|||. .   ..|.|||.  .|.. ..||.|...|..   ....|.|.|.||.||. |.|.| . .
kdtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgv

MISIIAAVQKQQQQS-GNHPITVHCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
....  |.|.|..   . || |||||| ||||||  . .||. .. .|.   .|. ...|..| ||  .||| .||.| ||.|| || 
vlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyi

Phosphatase PTPRA.AA Subfamily.N3.PD 256-502 38 2.2e-68 222.1 In-house 17-260 (261) Show / Hide
Range on Protein: 256-502
Range on HMM: 17-260/261
Sequence Identity: 38% (95 aa)

TCEAASKEENKEKNRYVNILPYDHSRVHLTPVEgvpdSDYINASFIN----GYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCA
...|| | || .|||| .|||||. ||.|.  |    .|||||...|    . .  |..||.||| ..|..|||.|.|||.. .|||.|.| |||| |||
aisaarkpenlaknryrdilpydatrvklkese----tdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkCh

QYWPDQG-CWTYGNIRVSVEDVTVLVDYTVRKFCIQQvgdmTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTG
|...  ...|...| .|       | .|......    .. | .| |.|. ...||| |||  .  .|.|...|...       .|||||||.|||| ..
qyWPetedelefgefsvrcekedetksyvlrelvlkd----ketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtG

TFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY
...  | .. ....| .   |...| ||  .|||  || |. .|.|. |   
vlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailkay

Phosphatase PTPRA.AA Subfamily.N_Choan_2.PD 264-501 34 9.2e-66 213.5 In-house 20-264 (266) Show / Hide
Range on Protein: 264-501
Range on HMM: 20-264/266
Sequence Identity: 34% (86 aa)

ENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQE-KNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDqgcWTY
||. ||| .|||  ..|| | ..|  . . |||| ...|... |.|.|||.||.. |...|||||||... .|||.|.|.|.   ||..|||     .  
rnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpa---epk

GNIRVSVEDVTVLVDYT-VRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPI------GMLKFLKKVKACNPQYAGA--IVVHCSAGVGRTGTFV
.....  ...||.  .  ... |..   ..... .| .. |....||| ||| ..        .|| |..|... . . |  ..||||||||||||...|
ekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtli

VIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
| .. ......||||   ....| .|...||.  || ..|.|..|.  
aiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavvey

Phosphatase PTPRA.AA Subfamily.RN.PD 254-500 39 9.6e-66 213.5 In-house 16-261 (264) Show / Hide
Range on Protein: 254-500
Range on HMM: 16-261/264
Sequence Identity: 39% (96 aa)

QATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKN-KFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQ
..|.|.|..|.| .|||. ..||||||||.|.      .|||||||.|   . ..  .||.|||  .|. |||.|.||| .. ||..|.|.|.|..||||
pstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckr

YWPDQGCWTYGNIRVSVEDV-TVLVDYTVRKFCIQQVgdmtNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGT
.|  .|.   | .        || || | ....    . .  | .||||| |||. ||| ..  .|.| .||  .    . .||||||.|.||||....|
ywpdeGsevyhiyevhlvsehiwcddylvrsfylknl----qtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGv

FVVIDAMLD-MMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE
| .|. ...  ...|.   .  .| || ..|.|  |. |...|. |    
yilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae

Phosphatase PTPRA.AA Subfamily.N14.PD 243-500 31 2.5e-62 202.4 In-house 4-272 (275) Show / Hide
Range on Protein: 243-500
Range on HMM: 4-272/275
Sequence Identity: 31% (87 aa)

EEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVpDSDYINASFINGY--QEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVT
|.. .|    .|....|. .||.||||. ..|||...||.|.| .   ...||||| |.     .. ..|.|||| |.||.|||.|.|||... |||.|.
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlt

NLKERKECKCAQYWPDQ----GCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVgdmtNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQY--
 .|    |. .|.|..       ..|. .|. . ..    .. ... .. .      | .| .  . .| ||| |||  . |.|.||..|..   .    
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhl----pskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktns

--------AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE
          ..|||||||||||  .. | ..  .......|.   ..|.| ||  .|||  || |.|..|.. 
evesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlik

Phosphatase PTPRA.AA Subfamily.N1.PD 255-501 34 7.4e-59 191.2 In-house 18-266 (268) Show / Hide
Range on Protein: 255-501
Range on HMM: 18-266/268
Sequence Identity: 34% (86 aa)

ATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGvpdsDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYW
...| ..||...||| .. ||||||..|   .     ||||||...  . | ..| .|||  .|.. ||.|.||||. ...|. .. |...||||||| .
letreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqyw

PDQGC---WTYGNIRVSVEDVTvlvdYTVRKFCIQQVGDMTN--RKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKAC--NPQYAGAIVVHCSAGVG
      .. ... .|. ..      .... ...   ...   .  | |..||.| ||||||| .|  .|||| ||.      .|..|.|||||.||.||.
pqeeeeaellleetklkvklis----eerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagig

RTGTFVVIDAMLDMMHTERK---VDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
...|..|  .  . .   ||.   .  .| .|  ..||  |  | |.|.||      
rsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaileg

Phosphatase PTPRA.AA Subfamily.N23.PD 276-501 33 3.3e-56 182.6 In-house 113-348 (350) Show / Hide
Range on Protein: 276-501
Range on HMM: 113-348/350
Sequence Identity: 33% (80 aa)

PYDHSRVHLT-PVEGVPDSDYINASFINGYQEK-NKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQG--CWTYGNIRVSVED
|..||.|    .    .|||||...        .|||.|||...|..||| |.||| . .|||.|. .|..  ||.|||| .     ..|..|||.....
rhdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslks

VTVLVDYTVRKFCIQqvgdMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACN-----PQYAG----AIVVHCSAGVGRTGTFVVIDAML-DM
    .  |.. .|    ... .  ||....|.|.|...|||  |  .|.||..|...       . .|     |..|||||||||||| |. . . .. .
lrssegwiervlhlq----hndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysairel

MHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
 .  ...   |.|.|.||  |||.  .. ..|.| ||.  
tagngiiniprvvrrlrqqRkymvqkkvilkklyeavlea

Phosphatase PTPRA.AA Subfamily.N_Nematode_1.PD 242-502 32 1.6e-55 180.0 In-house 3-264 (265) Show / Hide
Range on Protein: 242-502
Range on HMM: 3-264/265
Sequence Identity: 32% (87 aa)

REEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTpvEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN
|.||.||     . . .| .......|||| ..   |..|| |.  |.   |||| | ..    . ..|| ||.|...|..||||.  ..  .|||. .|
rdefralkkfndeekvkafkeaqeadknrykdvgcldknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlck

LKERKECKCAQYWPDQG----CWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNR--KPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACnpqyA
 |. . |||.|.| .      .. .. ...||...     .  . .|..     .   . .| .|....| ||| ||| . ...|..|..|..      |
liekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgs----k

GAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKV-DVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY
 ||||||||.||||| |.|. .|| .  .... |.  .| .|| ||   .|||.||.|... ||... 
gPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllnyf

Phosphatase PTPRA.AA Subfamily.N_Nematode_4.PD 254-502 31 4.2e-55 178.7 In-house 15-263 (264) Show / Hide
Range on Protein: 254-502
Range on HMM: 15-263/264
Sequence Identity: 31% (79 aa)

QATCEAASKEENKEKNRYVNILPYDHSRVHLTpvEGVPDSDYINASFINGYqEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQY
.... |   |.|..|||| .||  |..|| |   .  || ||| ||..    .| ..|..||| .||..||| |.... .|..||. .| |    |||.|
ppnvtasaseknsdknryadilcidetrvvlk--nrdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcary

WPDQGCW--TYGNIRVSVEDVTVL--VDYTVRKFCIQQVGDMTNRKPQRLI-TQFHFTSWPDFGVPFTPIGMLKFLKKVKAcnPQYAGAIVVHCSAGVGR
.|..     ..|. |. . . ..    |  .. . . .. .  .   ..|.   .... |.|   | ... ..|..| ||   ..  . |||||||||||
ypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGr

TGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHY
| |.| ||    ...   ...|   | ..|| | . ||...|..|..  |.|..
tatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvlielf

Phosphatase PTPRA.AA Subfamily.N20.PD 244-500 35 1.4e-47 154.2 In-house 5-254 (257) Show / Hide
Range on Protein: 244-500
Range on HMM: 5-254/257
Sequence Identity: 35% (91 aa)

EFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPvegvpDSDYINASFING--YQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN
|| ||    .    ..  .  |.||||| .||||| .|| |         ||||||.|      |.  .||.|||   |..|||.|. |.|.| |.|   
efmalelknlpgefnsgnqpsnreknryrdilpydstrvplgk-----skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitr

LKERKECKCAQYWPDQ--GCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTnrkpQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKacNPQYAGAIV
|    || .|||           .|| .|.  .|  . .| | . .    |     . . |..|| |||.| | .   ..|....  . . .| .|||||
eieggiikcyhywpislkkplelkhfrvflenyqilqyfiirmfqvvekstgt----shsvkqlqftkwpdhgtpasadsfikyiryar--kshltgpmv

VHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLE
||.|||| |...| ..  .  .  ...   |...| ||. ||||  || | |. .||    
vhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivle

Phosphatase PTPRA.AA Subfamily.N_Nematode_6.PD 256-501 28 3.6e-47 152.8 In-house 15-251 (253) Show / Hide
Range on Protein: 256-501
Range on HMM: 15-251/253
Sequence Identity: 28% (71 aa)

TCEAASKEENKEKNRYVNILPYDHSRVHLTPVEgvpdSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP
. || .  ..|..||| ||  .| .|..|.  |      || |....  ......| .|.| |.|...||.||  . .  |||..| |. . |.|.| .|
eseataflkfkdrnrytniqCcdagrlkladde----dfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeyls

DQG--CWTYGNIRVSVEDVTVLVDYTVRKfCIQQVGDMTNRKPqrLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNpqyaGAIVVHCSAGVGRTGTFV
.      ....   ..   . .| .. .  ....   ....   ..  .|. .||| ||| .    |..|. || ..      ||||||||||||||...
dkvGdarkitklctvikigrkdidkilvr-slkrivkagdeev--ivkhihWanWPdhGvPdsflsalrllsvvkkdk----kPivvhCsaGvGrtGtla

VIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
|  .|. . . .. .|   . ..| .| . ||| .||.. .. .||. 
liliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvley

Phosphatase PTPRA.AA PTPc_motif 399-500 41 6.4e-46 159.78 SMART 1-92 (92) Show / Hide
Range on Protein: 399-500
Range on HMM: 1-92/92
Sequence Identity: 41% (44 aa)

LITQFHFTSWPDF-----GVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVF
 ....|.|.|||.     |||    ..|.|...|..        ||||||||.||||||..|| |...      ||....| ..| ||..||||..||.|
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIF

IYQALLE
.|...||
CYRCILE

Phosphatase PTPRA.AA Subfamily.R_Nematode_2.PD 261-499 26 5.7e-43 138.9 In-house 25-257 (261) Show / Hide
Range on Protein: 261-499
Range on HMM: 25-257/261
Sequence Identity: 26% (63 aa)

SKEENKEKNRYVNILPYDHSRVHLTpVEGVpDSDyINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQG--
.  .|.|.|| ..   ....|.   |.|   .. | | ...  .....|||.||| |.|..||| |.  ..  .|||...  |... ||..|.| .    
aaylpkdkhRypdvPCkpetavevi-vdgk-rvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsq

CWTYGNIRVSVEDVTVLVDYTVRKFCIqQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNpqyaGAIVVHCSAGVGRTGTFVVIDAM
 . |.... . ..  ...  . |  . .| | |.. . | .| . ...||| ||| . . . . |.||  .      ||||||||.|||..|. .. . .
kldlgrfsiktvsaekilkdeiekrtl-kvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkkse----kPivvhCsaGiGRtmafigteyl

LDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALL
 . ..... .   .  .| .| . .||. |. ..  ..|  
areveadptieltealkelrehRwkgiqtesqlywltlgal

Phosphatase PTPRA.AA Subfamily.N_Nematode_5.PD 242-501 24 3.1e-42 136.4 In-house 3-256 (258) Show / Hide
Range on Protein: 242-501
Range on HMM: 3-256/258
Sequence Identity: 24% (63 aa)

REEFNALPACPIQATcEAASKEENKEKNRYVNILPYDHSRVhltpVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTN
..||. | .  ..   .  . |.|..|||. ..  .|..||      . .|..||||| |.  . ..|.| .| |. .|..|||||. ... ...|....
ktefeklaslkpnke-tckafeknlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllve

LKERKECKCaQYWP--DQGCWTYGNIRVSVEDVTVLVDYTvRKFCIQQVGDMTNRKpqRLITQFHFTSWPDFGVPFTPIGMLK-FLKKVKACNPQYAGAI
 .| || .. ...|   .   ..|.. . .  |.|  |    ..... . .  . .   ...  |.||..  ||     ..|  ..||   . .    .|
deelketav-sffpletgdylnlgkmfinnrkvevkedek-keytvevlpegcses--vfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapv

VVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
|....|.||.|||...... . .... ....   .  || ||...|.. .||...|.|.|.. 
vvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldy

Phosphatase PTPRA.AA Subfamily.R_Nematode_3.PD 260-497 22 6.6e-41 132.2 In-house 18-261 (267) Show / Hide
Range on Protein: 260-497
Range on HMM: 18-261/267
Sequence Identity: 22% (56 aa)

ASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINgYQEKNKFIAAQGPK--------EETVNDFWRMIWEQNTATIVMVTNLKE---RKEC
| ... ...|.|... . ..|| |        .|.|.|....  ....|.| .|.|         ..|.. || || ......||. . .|   ..| ||
tslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeee

KCAQYWPDQ--GCWTYGNIRVSV-EDVTVLV-DYTVRKFCIqQVGdmtnRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNpqyaGAIVVHCSA
..|.|..  |  . ... |.  .  . |  |   |.... ..      |..  .|  ....|.. ..| .|  .|. .|.|....      .|||||.|.
kcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfe----kkkeftvthllykgWkelnapeepkealelikfveksk----tpvvVHCsd

GVGRTGTFVVIDAMLDMMHTER-KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQA
.|..|...|.   ... ... |.|.   .. .|.|| . .||.... |.     
GisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilg

Phosphatase PTPRA.AA Subfamily.N_Nematode_egg.PD 243-499 26 8.8e-30 95.8 In-house 4-253 (257) Show / Hide
Range on Protein: 243-499
Range on HMM: 4-253/257
Sequence Identity: 26% (68 aa)

EEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNL
..|. |     . . . | .....|| |   .   . |||.|   .|    |.| | ...|    |.|| || |  .||.|||||.....   |||.|  
rrfeilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsa

KERkeCKCAQYWPDQG---C-WTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMtnrKPQRLITQFhFTSWPDFGVPFTPIGMLKFLKKVkaCNPqyagaI
||    .|  |||           |..|.   .|    |   |   .. ||     . .. ..    .   .  ..|. .|. |...   .|     .||
kes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgd---deelflehw-qgdvnylsdvysplrvlrklrnl--skp-----v

VVHCSAGVGRTGTFVVID-AMLDMMHT-ERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALL
..  || ...|.| |. |.|...     |  |   |  .| .||.. ..|.|.|. .|     
vvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl

Phosphatase PTPRA.AA Subfamily.N_Fungi_PTP1.PD 265-358 34 2e-25 81.3 In-house 45-152 (343) Show / Hide
Range on Protein: 265-358
Range on HMM: 45-152/343
Sequence Identity: 34% (35 aa)

NKEKNRYVNILPYDHSRVHLT----PVEG----VPDSDYINASFINGY----QEKNK--FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKC
||||.|||||.||||.|     . ..    .  .|||||....      . . .  .||.|.|  .||.||...| . .|...|.. |    || .||..
lfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekc

AQYWPDQG
 .      
yrYWqegs

Phosphatase PTPRA.AA Subfamily.N_Nematode_eak.PD 258-414 27 3.2e-20 64.4 In-house 19-170 (281) Show / Hide
Range on Protein: 258-414
Range on HMM: 19-170/281
Sequence Identity: 27% (43 aa)

EAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDsDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQ
. ... |. ..|| |.|.|.|.  |.||.    .|  ||||| ..  .  .|.| .  ..|. |  ||.|. ||.. .||...  | |  |  .|.||..
rvtarleavnrnrvvkivpqdrylvrltssqlnrd-GyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdk

G-CWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRkpqrlITQFHFTSWPDFGVP
  . || . |   . .|  .    .  | ..|. | |     .  ...  | .. .| 
tevlkyGildverkeyavkrniletrllilrkGnethr-----vlhykvfGwtettlp

Phosphatase PTPRA.AA Subfamily.N_Fungi_PTP1.PD 399-500 33 1.1e-18 59.1 In-house 214-340 (343) Show / Hide
Range on Protein: 399-500
Range on HMM: 214-340/343
Sequence Identity: 33% (41 aa)

LITQFHFTSWPDFGVPFTPIGMLKFLK-KVK----AC-----NPQYAGAIVVHCSAGVGRTGTFVVIDAMLD---M----MHTERKVDVY--------GF
. |...  |.| .. . |. .|. |. | .     .     . . . .|.||||||||||||.| .| .|    .     .||.||           | .
evyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisii

VSRIRAQRCQMVQTDMQYVFIYQALLE
.| || .|||.  |..|||.|||    
vnelrkqrismvqnldqfifiYeallf

Phosphatase PTPRA.AA Subfamily.N_Nematode_eak.PD 421-501 27 1.7e-10 32.5 In-house 199-279 (281) Show / Hide
Range on Protein: 421-501
Range on HMM: 199-279/281
Sequence Identity: 27% (22 aa)

LKFLKKVKACNPQYAGaiVVHCSAGVGRTGTFVVIDAMLDMMHTERK--VDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEH
.||| .   | .|   .. .. |  |.|.||||| .. ..   .|    |  .. ... .|   | ...|. |||...|..  
rstlkkyihtppsfap--iiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldy

Phosphatase PTPRA.AA Subfamily.PTPDC1.PD 403-494 28 3.8e-10 31.4 In-house 137-220 (229) Show / Hide
Range on Protein: 403-494
Range on HMM: 137-220/229
Sequence Identity: 28% (26 aa)

FHFTSWPDFGVPfTPIGMLKFLKKVKACNpqYAGAIVVHCSAGVGRTGtfVVIDAMLdmMHTeRKVDVYGFVSRIRAQRCQMVQTDMQYVFI
|.  ...|.||. .   .|   | |.       |.| ||| || ||||  |.| ..|  ... ....    .. .|..| . .||  |..  
fynfglkDygva-sleriLdivkvvdfal--eegkiavHCHAGlGRtG--vliacyl--vya-krltaeeaiklvrskrpksiqtreqvelv

Phosphatase PTPRA.AA Family.DSP.PD 372-496 20 4.1e-10 31.3 In-house 133-241 (387) Show / Hide
Range on Protein: 372-496
Range on HMM: 133-241/387
Sequence Identity: 20% (26 aa)

VTVLVDYTvrkfciqqvgdmtNRKPQ---RLITQFHFTSWPDFGVPFTP-IgMLKFLKKVKACNPQyAGAIVVHCSAGVGRTGTFVVIDAMLD-MMHTEr
||. |. |               |||   .|  ...  ...|...|    . . |... .. .| .  | ..||| ||.||.|| ...  |    .|   
vtkivnlt-------------ddkpqftkelgikylripidDhnapplenl-fekaidfieegnds-kgvVlVHCkaGkgRsgtliiaYlmksegltle-

kvDVYGFVSRIRaqrcQ-MVQTDMQYVFIYQ
. . .|.  |    . ...   ...  ..  
--ealdwvrskR----pgvitpnqgflkqlk

Phosphatase PTPRA.AA Subfamily.CDC14.PD 420-458 41 2.5e-07 22.5 In-house 187-221 (258) Show / Hide
Range on Protein: 420-458
Range on HMM: 187-221/258
Sequence Identity: 41% (16 aa)

MLKFLKKVKACnpqyAGAIVVHCSAGVGRTGTFVVIDAM
. |||. .  .     |||.||| ||.|||||..    .
lkkfleiteka----eGaiavhCkaGLGrtgtligcyli

Phosphatase PTPRA.AA Subfamily.DSP23.PD 404-494 21 9.2e-07 20.8 In-house 37-120 (128) Show / Hide
Range on Protein: 404-494
Range on HMM: 37-120/128
Sequence Identity: 21% (20 aa)

HFTSWPDFGvPFTPIGMLKFLKKVKACNpQYAGAIVVHCSAGVGRTGTFVVIdamldMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFI
.  . |||  | ..  . .... |.  . .  .|. |||  |.|||||..        .  |...     .  .| .|   ..|  |   .
rridipdfc-PPaleqvarlvriveeae-kkeeavgvhcalGlGrtGtllac-----ylvkeeglaaddaiaevrkrrkGsietveqekav

Phosphatase PTPRA.AA Subfamily.PTEN.PD 438-514 21 1.8e-06 19.3 In-house 97-175 (305) Show / Hide
Range on Protein: 438-514
Range on HMM: 97-175/305
Sequence Identity: 21% (17 aa)

IVVHCSAGVGRTGTFVVIDAMLDMMHTER--KVDVYGfVSRIRAQRCQMVQTDMQYVFIYQALLEH-YLYGDTELEVTSL
..||| || ||||. ..   .  .. ..    ...|.   | . ...  .     ||  .. |..    |    |.|. .
vavHCkaGkGRtGvmicayLlksgikksadealaiyd-ekRtkdkkGVtiPSQrRYvqYfsklvkssvpyskvslnvcei

Phosphatase PTPRA.AA Subfamily.DSP19.PD 423-481 23 8.7e-06 17.5 In-house 71-120 (139) Show / Hide
Range on Protein: 423-481
Range on HMM: 71-120/139
Sequence Identity: 23% (14 aa)

FLKKVKACNpqyaGAIVVHCSAGVGRTGTFVVidAMldMMHtERKVDVYGFVSRIRAQR
|.....  .    |...|||.||| |. ..|.  |   .|. ......   ....|..|
Fieearskd----grvlvHCnAGvSRsasvvi--ay--lmk-deelslekalekvrear

Phosphatase PTPRA.AA Subfamily.RA.PD 533-793 69 2.5e-151 494.2 In-house 2-266 (266) Show / Hide
Range on Protein: 533-793
Range on HMM: 2-266/266
Sequence Identity: 69% (183 aa)

LEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVML
||||||||||.|||..|.||.|...|.|||||.||.||.|.|||..||.|||..||.|||||||||.||..||.|||. .|.|||||||||.||..||||
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativml

TELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVT----NTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPI
|||.||..||||||||..|||.||.|.||.|.|...|.|||||.|||    .|||.|||..|||||..|||||.|..||||......|.|.||||.||||
telkerkeekcaqywpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpi

TVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID
.||||||.||||||..|..||||||||..||||..||.||||||.||||||||||.|||..||||
vvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlleyid

Phosphatase PTPRA.AA PTPc 532-793 38 2.1e-134 453.7 SMART 1-308 (308) Show / Hide
Range on Protein: 532-793
Range on HMM: 1-308/308
Sequence Identity: 38% (120 aa)

GLEEEFKKLTSIKIQN--------DKMRTGNLPANM--KKNRVL-QIIPYEFNRVIIPVKRGE----ENTDYVNASFIDGYRQKDSYIASQGPLLHTIED
|..|||..| . ....        ........|.|.  .|||    |..|. .||... . ||    |..||.||..||||... .||. |||| |||||
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMIWEWKSCSIVMLTELEER--------GQEKCAQYWPSDGLVSYGDITVELKKEEECE-SYTVRDLLVTNTRE--------NKSRQIRQFHFHGWPE
||||.|. |...||||....|.        |.|||.||||..  . ||.|||..|.|| |. .||.|.. |||| .        ...|.....|...||.
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPD

VGIPSDGKGMISIIAAVQKQQQQSGN------------------HPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQY
 |.|.. ......| .| ..|..|.|                   || ||||||.||||||||..........   .|.||.||..| |||.||||.|||
HGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQY

EFCYKVVQEYID
 |||....||| 
IFCYRCILEYIK

Phosphatase PTPRA.AA Y_phosphatase 558-790 45 3.7e-126 430.23 Pfam 1-243 (243) Show / Hide
Range on Protein: 558-790
Range on HMM: 1-243/243
Sequence Identity: 45% (111 aa)

NMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDG-YRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQ-EK-CAQYWPS---DG
|..|||   |..|...||. . ..|.|..||.||..||| |...  ||. |||. |||||||||.|. |. .||||....|.|. || |.||||.   ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

LVSYGDITVELKKEEECESYTVRDLLVTNTRE--NKSRQIRQFHFHGWPEVGIPSDG-KGMISIIAAVQKQQQQSGNH--PITVHCSAGAGRTGTFCALS
 ..|||..|....||.|. ||||.. |||  .  ...|.....|...||. |.|... |.|...|  |.|.|.....   ||.||||||.||||||||..
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAID

TVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQE
........||..|.||.||..| |||.||||.|||.|||....|
IMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase PTPRA.AA Subfamily.R_Anemone_2.PD 533-792 50 2e-106 347.1 In-house 2-261 (262) Show / Hide
Range on Protein: 533-792
Range on HMM: 2-261/262
Sequence Identity: 50% (131 aa)

LEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVML
|.||...|.  . .. .... . |.| .|||   |..|.  || .  . |||..||.||..|||||.| .|||.|.|| .||||||||.|| .|. ||||
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHC
|..||||. |...||||.|  |||...||||.| |...|..| . |..|.|...||.||||.  ||. |.|..| ......  |.| ||.||..||.|||
tqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhc

SAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
||| ||||.|.|....|||.|||...||||||| || ||. |||| .||||.|.|..|..
saGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal

Phosphatase PTPRA.AA Subfamily.R_Sponge_2.PD 544-793 45 2.2e-97 317.5 In-house 11-262 (262) Show / Hide
Range on Protein: 544-793
Range on HMM: 11-262/262
Sequence Identity: 45% (116 aa)

KIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVkRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKC
| .. .. ...|. |. |||. .|.||...|| .    |....||.||||.|||.....|||.|||| .|.||||||.|| |. .|||||.|||.|.|||
ketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekc

AQYWPSD--GLVSYGDITVELKKEEECESYTVRDLLVTNTRE-NKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTG
|.|||.   . |.||...| ||.||. . |..|.| ...... .......||||  ||| . |.|   ....|. |...|..|||..|||.||.|.||||
akYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtG

TFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID
||.|| .||||.|||. .|||...|.|| .|. .||. .||.|......|||.
tfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyie

Phosphatase PTPRA.AA Subfamily.R_Anemone_1.PD 533-792 38 7.4e-92 299.5 In-house 2-257 (258) Show / Hide
Range on Protein: 533-792
Range on HMM: 2-257/258
Sequence Identity: 38% (101 aa)

LEEEFKKLTsiKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVML
...||..|.  .|..... ... ..| ||||. .|....  ||..  . ..|..||.|||...........||.|.|| .|.||||||.|. |...||||
yaaefqrlk--eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmL

TELEERGQEKCAQYWPSdGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQqQQSGNHPITVHC
|.|.|  ..|| ||||. .  .||...|.|.|.|.   |..| |......|...|...|.||  ||. |.|.  . ....   |||. ...|..|. |||
tnliegekkkchqYwPd-stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks-slagarpvvvhC

SAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
||| ||||.|......||..|.| ..|.|..||..| .||||||| ||| |....|.|..
saGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal

Phosphatase PTPRA.AA Subfamily.RK.PD 533-792 40 6.6e-86 279.6 In-house 2-266 (267) Show / Hide
Range on Protein: 533-792
Range on HMM: 2-266/267
Sequence Identity: 40% (108 aa)

LEEEFKKL--TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEeNTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIV
| |||. |   . ..| ... .. .. | .|||. .|..|.  .|.. .  |. ..||.||..||.|..   .|. |||| .|..||||.......||||
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

MLTEL-EERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTN--TRENKSRQIRQFHFHGWPEV-GIPSDGKGMISIIAAVQKQQQQSGNH
||||  |.|. || .||| |. | |||| ||| . |  . . || . |..     .. |..|||.| ||||  ..|   ......|.|.|.|..... .|
mlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeG

PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
 |||.|||||.|||.|...||| .. ||..|||..||.|| ... ||.| |||.|.| |. |..  
rivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal

Phosphatase PTPRA.AA Subfamily.RG.PD 533-792 39 1.5e-85 278.6 In-house 2-263 (264) Show / Hide
Range on Protein: 533-792
Range on HMM: 2-263/264
Sequence Identity: 39% (101 aa)

LEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVML
|||.|......| .. .. . . . | .||| ..|...|  || .  . |....||.|||.|||||..  ||..|||| .||||||||||| ..|||||.
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

TELEERGQEKCAQYWPS-DGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQ--IRQFHFHGWPEVGIPSDGKGMISIIAAVqKQQQQSGNHPIT
|.|.|......|||. |. .......| |...|. ..|||||... ||. .|...  .||.|.  ||..| |.    ... ... ... . ||.||.|||
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkke-eaankeeaGPiv

VHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
.||.||..||.|.|.....| . .|.|..| .|..||..|.| ||| | |....| .      
vhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallelv

Phosphatase PTPRA.AA Subfamily.RB.PD 534-791 40 2.2e-85 278.0 In-house 3-259 (261) Show / Hide
Range on Protein: 534-791
Range on HMM: 3-259/261
Sequence Identity: 40% (104 aa)

EEEFKKLTSIKIqNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLT
.||...|....  ...... ....| .|||. .|.||. .|| .   . |..|||.||..|.||...  |||.|||| .|..|||||.|| |||||||.|
seeyeelkkvgk-dqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

ELEERGQEKCAQYWPSDG-LVSYGDITVELKKEEECESYTVRDLLVTNtrENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQS-GNHPITVH
 |.|.||| .|||.|   | ||||.|.|..|.| .....|.. ...  ....|..||.||  ||. |.|.. | ..... .|......  ..|| |||||
qlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvH

CSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY
| |||||| || ..|...... ..||| .| .|| .| ..|||..|| | .......   
CsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl

Phosphatase PTPRA.AA Subfamily.R_Ecdysozoa.PD 532-792 39 4.4e-85 276.9 In-house 1-268 (269) Show / Hide
Range on Protein: 532-792
Range on HMM: 1-268/269
Sequence Identity: 39% (107 aa)

GLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVM
.||||..|| .    . . ....   |  |||  .|.... .||....  |.|..||.||||| ||..| ..||.|.|.  ||.||||||.| ..  |||
kleeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivm

LTELEERGQEkCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTR---ENKSRQIRQFHFHGWP-EVGIPSDGKGMISIIAAVQKQQQQS----
|..|.|  .. ||.||| .  | |||| |.| .||... |. |.| |...    ...||.. |... ||... .|   .|.. .|  |.. ....     
lsnlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsg

GNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
. ||.||||||.||.|.| ||. .|...|||  .|.|.||| || ||. .|| ||||.|.|. . .|. 
srsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyraladys

Phosphatase PTPRA.AA Subfamily.N9.PD 532-791 40 3.2e-82 267.9 In-house 1-273 (275) Show / Hide
Range on Protein: 532-791
Range on HMM: 1-273/275
Sequence Identity: 40% (110 aa)

GLEEEFKKLTSIKIQnDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVM
|| .|.... . ...  .. . .|.||..|||   .. |.  || .. . ..|..||.||.|.|||.||...||.|||| .|..|||||.|| .||| | 
Glskeyadirnepve-GtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivm

LTELEERGQEKCAQYWP--SDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQS------
..|||. ||.||||  ..   ..||..|.  . |. | |.|| | ..|.....||..  | | .||. |.||... .. .. .|...| ..         
ttrvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgd

------GNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY
    . || |||||| ||||||..|   |.|.. .| .||..||| || || ...|| |||||||. | ||   
eskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley

Phosphatase PTPRA.AA Subfamily.N_Choan_1.PD 532-793 37 1.7e-79 258.8 In-house 1-262 (262) Show / Hide
Range on Protein: 532-793
Range on HMM: 1-262/262
Sequence Identity: 37% (100 aa)

GLEEEFKKLTSIKIQNDKmRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVM
|. ||..||..| ..|   .  . ..|..|||   |. |.  || .. .  ..||||.||.|..||...  |||.|||. .....||.|.|| | . |||
Gfieeyeklaeigvdnta-taskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivm

LTELEERGQEKCAQYWPSDG-LVSYGDITVELKKEEECESYTVRDLLVtNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITV
.|.  | |. || .||| .   ...||.||. ..||| ..|  | . . .......|...|...  ||. |.|.. | ...  .||.|..... ..|. .
vtreieagklkChryWPdenselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvi

HCSAGAGRTGTFCALSTVLERVKAEG-ILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID
||||| |||||. || .....|...   ||| ..|..|| .|  ||||| |||| ||.|....|
hCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldald

Phosphatase PTPRA.AA Subfamily.N12.PD 534-792 42 4.1e-79 257.3 In-house 3-269 (270) Show / Hide
Range on Protein: 534-792
Range on HMM: 3-269/270
Sequence Identity: 42% (114 aa)

EEEFKKLTS--IKIQNDK---MRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCS
..||.|| .   | ...|     .|. . |.||||   |.||...||..  ...||. ||.||.|| | ..| .|||.|||| .|..|||||||| .   
akefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknvei

IVMLTELEERGQEKCAQYWPSDG--LVSYGDITVELKKEEECE-SYTVRDLLVTNTreNKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQqSGN
.||. .. | |. ||..|||. |   . .|...|.|..|. ..  ...| | |..   ..||...|||.. ||. |.||  | ....|..|.. |. | .
vvmaCrevelgkkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqe-sed

HPITVHCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
.|. |||||| ||||| .|.  | | .||| |   ||||. | .|| ||. .||| ||||. || |.|..
aPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv

Phosphatase PTPRA.AA Subfamily.RC.PD 533-791 37 2.3e-75 245.3 In-house 2-286 (288) Show / Hide
Range on Protein: 533-791
Range on HMM: 2-286/288
Sequence Identity: 37% (109 aa)

LEEEFKKLTSIKIQNdKMRTGNLPANMKKNRVLQIIPYEFNRVII-------------------PVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHT
|| ||..| |.. .   .. .. . | .|||  ...||..||| .                       .|| ..|.||||||.|.. . |||.||||  |
leaefqrlpsvrskr-tikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplket

IEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWpSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISII
..||||||.| |   |||||||.|  .||||.||  .|  .|||. |.||... . .|..| | . | .. .||.. |. .  |.. ..| . | ....|
vddfwrmiferkvkvivmltelkeGdrekcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkli

AAVQKQ--QQQS--G-----NHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY
  |...  |..|  .       |. |||..|..|||.|.|| ..|| ..||  .|||| || || .|| ||.. ||| . |.|. |.
qvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet

Phosphatase PTPRA.AA Subfamily.N5_RR.PD 547-792 34 1e-69 226.7 In-house 12-264 (265) Show / Hide
Range on Protein: 547-792
Range on HMM: 12-264/265
Sequence Identity: 34% (87 aa)

NDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEEN-TDYVNASFIDGYRQK-DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCA
| ...  ... . .|||  .|.| |  ||..  . .|.. ..|.|| .| ||...   |.| |||| .||.||||||.. ..  |||||.|.|. ..|||
nfsqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkca

QYWPSDGLV----SYGDITVELKKEEECESYTVRDLLVTNTREnKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNH--PITVHCSAGAGR
.|.| .  .     |||. .. ..  |.. |.|| |.......  .|..  . .  ||.   | | . ...... |....... ..  |. |||||| ||
vyfPdaedyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGr

TGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
|| | | |  . ....|...||...|  |||.|  |||| ||||. .... .| 
tGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl

Phosphatase PTPRA.AA Subfamily.N13.PD 534-790 37 9.6e-67 217.0 In-house 3-256 (259) Show / Hide
Range on Protein: 534-790
Range on HMM: 3-256/259
Sequence Identity: 37% (97 aa)

EEEFKKLTSIKIQnDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGeentdYVNASFIDGYRQKDS--YIASQGPLLHTIEDFWRMIWEWKSCSIVM
.||||.|  .| . |. ..|.  .|..|||  ...||.  ||..  . |     |.|||.|    ..|   |||.|||| .|..|||.|.|||.  |.|.
aeefkelrelkpl-dtcevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviam

LTELEERGQEKCAQYWPSD---GLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQqsGNHPI
|   |.|. || .|||.     |. .. ..||| | .. ....||.| |.... ..||.. ...|  ||. |.||  . .. ..||.. |.   . || |
vtlekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt--dagPi

TVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQE
||||| ||.|.. .. .||. .. .  .|| ..|..|| ||  .||| .|| |.||.. |  
vvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile

Phosphatase PTPRA.AA Subfamily.N3.PD 549-789 37 1.6e-66 216.0 In-house 17-258 (261) Show / Hide
Range on Protein: 549-789
Range on HMM: 17-258/261
Sequence Identity: 37% (92 aa)

KMRTGNLPANMKKNRVLQIIPYEFNRVIIpvkrGEENTDYVNASFI----DGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCA
. . ..|.|..|||   |.||.  ||..     |..|||.||...    ..  .   |||.|||| .| .|||.|.|| ||  |||||.| |||. || |
aisaarkpenlaknryrdilpydatrvkl----kesetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkCh

QYWPSD-GLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQqQSGNHPITVHCSAGAGRTGTFC
|||.    ...|...|...||.| .|| .|.|..........|.| |. .  ||. |.|.| . .....  |.| . .. ..|. |||||| |||| . .
qyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr-sgkeePvvvhCsaGigrtGvli

ALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEF-CYKVVQ
| | |  . |.  . . . |. .| ||  .||| .||.| |  ... 
lletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailk

Phosphatase PTPRA.AA Subfamily.RN.PD 533-791 39 1.3e-64 209.8 In-house 2-262 (264) Show / Hide
Range on Protein: 533-791
Range on HMM: 2-262/264
Sequence Identity: 39% (101 aa)

LEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFI-DGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVM
||.|.. |.. . ..    ... . |.||||. ...||. .|| .  .  .|..||.|||.| |   .. .|||.|||| .|| |||.|.||.. ||.||
lekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivn

LTELEERGQEKCAQYWPSDGLVSYGDITVELKKEE-ECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQsGNHPITV
.||| | ..|..||| .|   |.   |.|  |   |. | || . . | . ...| . ||||  ||| |.|.  | ..     |.|.     || ||||.
ltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG-rscpivv

HCSAGAGRTGTFCALSTVLERVK-AEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY
||||||.....  ||||..     .|.  |.. || |||..|.| .|.||....| |     
hcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee

Phosphatase PTPRA.AA Subfamily.N_Choan_2.PD 546-792 34 4e-64 208.2 In-house 6-265 (266) Show / Hide
Range on Protein: 546-792
Range on HMM: 6-265/266
Sequence Identity: 34% (88 aa)

QNDKMRTGNLPA---NMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQ-KDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQE
..... . ..|.   | . ||  .|.|    ||...  . ...| |.|| .. |. . | .|||..|||  |...||||||| |. .|||.|.|||.|..
dkqevseeaiPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrk

KCAQYWPSD--GLVS--YGDITVELKKEEECESYTVRDLLVTNtrENKSRQIRQFHFHGWPEVGIPSDGK------GMISIIAAVQKQQQQSGNH-PITV
||..|||..    |.  .|.|.|   .||  | | .. | ...  ....|... |... ||. |.|........||.. ...  .  |. |||||| |||
kCerYWpaepkekvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllv

HCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
||. |. .... .. .. .|| . .. || .|. .||. ||||. ||.|.||.         
HcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya

Phosphatase PTPRA.AA Subfamily.N14.PD 536-792 34 4.5e-60 195.0 In-house 5-274 (275) Show / Hide
Range on Protein: 536-792
Range on HMM: 5-274/275
Sequence Identity: 34% (92 aa)

EFKKLTSIKIqNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEeNTDYVNASFIDGY--RQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLT
|. ...  .  . .. |..|| | .|||. ...||| ||| .   . . .|.|.||| |      .. |||..|||| .|..|||.|.|| .|||||| |
eyeripkkre-dallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlt

ELEERGQEKCAQYWPSD----GLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQK---QQQ-----
| |.||. .|.|..      | .|   |  |  |. .|.. . | .     .. |..  . .  ||. |.|.| ||..| .||    . .      .. .
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseves

-QSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
 |. ||||||.||||       ... .. .  .|. .... || || ..|||| ||.| |||. .|.     
vkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikyl

Phosphatase PTPRA.AA Subfamily.N23.PD 574-791 32 9.1e-58 187.7 In-house 118-348 (350) Show / Hide
Range on Protein: 574-791
Range on HMM: 118-348/350
Sequence Identity: 32% (75 aa)

RVIIP-VKRGEENTDYVNASFIDGYRQ-KDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD--GLVSYGDITVELKKEEECE
|| .    . ... ||.||...        ..||.|||.  |. ||| |.|| .|  |||||. .|... ||.|||| |    ...||..| ||.... |
rvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrsse

SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQ-----QQ---SGNHPITVHCSAGAGRTGTFCALSTVLERVK-AEGILDV
 .  |.| .. .  .. |.. ..|.  |.|.|.|.  . .. .. .|..        .    |..|| .||||| ||||||| . .... ..  .||...
gwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngiini

FQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY
 . |. || || .|||. ......|..| |.
prvvrrlrqqRkymvqkkvilkklyeavlea

Phosphatase PTPRA.AA Subfamily.N1.PD 548-789 32 2.9e-53 172.8 In-house 18-264 (268) Show / Hide
Range on Protein: 548-789
Range on HMM: 18-264/268
Sequence Identity: 32% (80 aa)

DKMRTGNLPANMKKNRVLQIIPYEFNRVIIpvKRGEEntDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYW
..|. .||.| ..||   . ||.  |...  .|..   ||.|||...  . | .|| .|||| ||.. ||.|.|| .| ...|| .. |..||||||||.
letreaklpenrglnryrdvspydhsrikl--eradv--dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqyw

PSDGL---VSYGD--ITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNH-PITVHCSAGAGRTGT
.     . . .  ..|.| .||. . ..|| | ... .....|.| .||.  ||..|.|.  . .....  |..    | .. |..||||| ||.||.. 
pqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgt

FCALSTVLERVKAEGI---LDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQ
..|.| .. ..|    .|. . .  || .|  ..|| .| .| |  .    
lslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiail

Phosphatase PTPRA.AA PTPc_motif 688-790 41 1.7e-45 158.39 SMART 1-92 (92) Show / Hide
Range on Protein: 688-790
Range on HMM: 1-92/92
Sequence Identity: 41% (45 aa)

QIRQFHFHGWPEV-----GIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYE
.....|...||.      |.|.  ......|..|.|        || ||||||.||||||||.......      .|.|||||..| |||.||||.||| 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYI

FCYKVVQE
|||....|
FCYRCILE

Phosphatase PTPRA.AA Subfamily.N20.PD 543-791 37 7.6e-45 145.3 In-house 11-255 (257) Show / Hide
Range on Protein: 543-791
Range on HMM: 11-255/257
Sequence Identity: 37% (90 aa)

IKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRViiPVkrGeENTDYVNASFIDGYR--QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQ
.|    .. .|| |.| .|||  .|.||.  ||  |.  | .. ||.|||.|      ..  |||.||||| ||.|||.|. | .|  | |.|| |  ||
lknlpgefnsgnqpsnreknryrdilpydstrv--pl--g-kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggi

EKCAQYWPSD--GLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQqsgNHPITVHCSAGAGR
 .|||      .    . | |.. .  . . .| . | .     |. ..|..|  ||. | |.    .|  |   .| .|. |||||| |||| | ..  
ikcyhywpislkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshl---tgpmvvhcsagigr

TGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY
|.  .  .  ..... |  .| ||  |||| ||| ||| .| |          
tgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlev

Phosphatase PTPRA.AA Subfamily.N_Nematode_1.PD 533-792 31 1.2e-44 144.4 In-house 2-264 (265) Show / Hide
Range on Protein: 533-792
Range on HMM: 2-264/265
Sequence Identity: 31% (84 aa)

LEEEFKKLTSIKIQNdKMRTGNLPANMKKNRVLQIIPYEFNRVIIpvKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVML
| .||..|   . .. |... .   . .|||   .   . |||..  ...   .||. | ..    .   .| .|.|| .||.||| |.   |  .||||
lrdefralkkfndee-kvkafkeaqeadknrykdvgcldknrvkl--aeeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivml

TELEERGQEKCAQYWPSDG--LVSYG----DITVE----LKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQqq
 .| |.|. |||.|.|.     ...      ||||     || || |.      |  .   .|.|........ ||. |.|.   ... ...||....  
ckliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgsk--

sgnHPITVHCSAGAGRTGTFCALSTVLERVK-AEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
    || |||||| |||||  |.. .|...   . | |. . ||..| || ..||  || | ..|. .|. 
---gPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllnyf

Phosphatase PTPRA.AA Subfamily.N_Nematode_4.PD 554-791 33 1.2e-44 144.5 In-house 22-262 (264) Show / Hide
Range on Protein: 554-791
Range on HMM: 22-262/264
Sequence Identity: 33% (81 aa)

NLPANMKKNRVLQIIPYEFNRVIIpvKRGEENTDYVNASFIDGYrQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDG--
.|..|||  .|.  . .||..  |  . . ||. ||..     |  ||..|||| .|..||| |... |   .||| .|.||.||||.|.|..    | .
aseknsdknryadilcidetrvvl--knrdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksek

LVSYGDITVEL--KKEEECESYTVRDLLVTNTR---ENKS--RQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKqqqQSGNHPITVHCSAGAGRTGTFCA
|.  ..|  ||||      .. | ||||    .  |    .. .... |..   | | . .| .. ||.|   .. ..|| |||||| ||| |.  .   
vvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk---kkkekPivvhcsaGvGrtatlvG

LSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY
  |..  . ..| . |. ||  | . ||.  |. | . |. |.    
idyatirirenseievldivrelramrlkavqshlqflfllvvliel

Phosphatase PTPRA.AA Subfamily.N_Nematode_5.PD 533-792 29 1.2e-43 140.9 In-house 2-257 (258) Show / Hide
Range on Protein: 533-792
Range on HMM: 2-257/258
Sequence Identity: 29% (79 aa)

LEEEFKKLTSIKIQNDkmRTGNLPANMKKNRVLQIIPYEFNRViipvKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVML
|..||.|| |.|....  .. .  .|.||||  ..  .. .||    |...|. .|.||| |.    . ..|  | || .|.||||||. . |  |.|.|
lktefeklaslkpnke--tckafeknlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvll

TELEERGQEKCaQYWP--SDGLVSYGDITVELKKE---EEC-ESYTVRdllVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISiIAAVQKQQQQ-SGN
.| ||  . .. ...|  ..    .|..... .|    |.. . |||    |     . |  ..  |.. |..  .|.. | .|  .|. .  ... . |
vedeelketav-sffpletgdylnlgkmfinnrkvevkedekkeytve---vlpegcsesvfakvyhlttWkkkkvPdkvkkvik-raiekvlskkqgkn

HPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
.|. |....|.||.||| .||.. | ....  ... ...|..| |||..|..| || . |..| .||
apvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldyi

Phosphatase PTPRA.AA Subfamily.R_Nematode_2.PD 541-784 25 1.3e-39 127.8 In-house 12-252 (261) Show / Hide
Range on Protein: 541-784
Range on HMM: 12-252/261
Sequence Identity: 25% (62 aa)

TSIKIQNDKMRTGNLPANMKKNRVLqIIPYEFNrVIIPVKRGEENTDyVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQ
.  .|....... .  ..  |.|    .| . .   . |.  .. .. . | ...   ..  .||.||||  | |||| |.|   ||||..  |. .|||
vvatidkesvtesaaylpkdkhRyp-dvPCkpe-tavevivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekek

EKCAQYWPSDG--LVSYGDITVELKKEEEC--ESYTVRDLLVTNTRE-NKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQqsgnhPITVHCSAG
..|.|..    .. | .... ...|.   .. ..| | |...    ..| .. . .. ||. |.|. .  .. .|.|...     || |||||| |||..
ekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek-----PivvhCsaG

AGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFC
| .   . ..|.|.  . . ...| || .|.. .|| .|. .       
iGRtmafigteylareveadptieltealkelrehRwkgiqtesqlywl

Phosphatase PTPRA.AA Subfamily.N_Nematode_6.PD 554-792 27 1.4e-38 124.6 In-house 20-252 (253) Show / Hide
Range on Protein: 554-792
Range on HMM: 20-252/253
Sequence Identity: 27% (67 aa)

NLPANMKKNRVLQIIPYEFNRVIIpvkRgEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSD--G
. .. ..||   |  ..  |. .     ...  |. |....   ..  .| .|.||  |||.||.||    . .|||| || |.|.||.|.| ..     
aflkfkdrnrytniqCcdagrlkl---a-ddedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGd

LVSYGDITVELKKE-EECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQqsgnhPITVHCSAGAGRTGTFCALSTVLE
  ....  ..| . .. .  .|| |..     ...  .. .|.. ||. |.| . .  . ....|.|...     || |||||| |||||.  . ..|| 
arkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk-----PivvhCsaGvGrtGtlaliliile

RVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
..     .| . .  || .| . |||  || . .. | ||. 
alrlpdfqgvkdllvklreerfravqtevqylyalrcvleyl

Phosphatase PTPRA.AA Subfamily.R_Nematode_3.PD 545-788 25 1.1e-35 115.0 In-house 10-262 (267) Show / Hide
Range on Protein: 545-788
Range on HMM: 10-262/267
Sequence Identity: 25% (66 aa)

IQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDgYRQKDSYIASQGPL--------LHTIEDFWRMIWEWKSCSIVMLTELE
.. |. . .| ......|  ... .| .||..       . |...|...    .. . | .|.|.          ||| || || . |. ..||| .  |
aklakknatslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfv

E---RGQEKCAQYWPS--DGLVSYGDITVEL--KKEEECESYTVRDLLVtNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQqqsgnHPIT
   ...|||..|.|   || .  ....|.   .|.|  |.   |.| | .  ..|  ...  ...||.| ..| . | ....| .|.| .      |. |
eedgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk-----tpvv

VHCSAGAGRTGTFCALSTVLERVK-AEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVV
|||.| .|..|. |   . . .   .| ||. . .|.|| ||.. .|| ... |   .. 
VHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgi

Phosphatase PTPRA.AA Subfamily.N_Nematode_egg.PD 533-792 27 8.6e-27 86.0 In-house 2-256 (257) Show / Hide
Range on Protein: 533-792
Range on HMM: 2-256/257
Sequence Identity: 27% (72 aa)

LEEEFKKLTSIkIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVML
||..|..|    ...  ..|     ...| |  ..   |. || . ..||    |.. | ...|    . .| .| ||  |||||||... |   |||||
lerrfeilers-vdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivml

TELEERgqEKCAQYWP---SDGLVS-YGDITVELKKEE-EC-ESYTVRDLLVTNTRenksrqIRQFHFHGW-PEVGIPSDgkgMISIIAAVQKQQQQSgn
   |   |.|  |||   |. ||   | . .|  | . .    ..|  | .  .. .   |  .|   ||   . | .  ..| .. |  .|. |..  |
tsakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgd------deelflehwqgdvnylsd---vysplrvlrklrnls--

HPITVHCSAGAGRTGTFCALSTVLERVKAEGIL--DVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYI
  ...|. |. . | ..    |    | ..|. |||.|.  |..  .| | |..|  .|          
kpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlffi

Phosphatase PTPRA.AA Subfamily.N_Fungi_PTP1.PD 559-667 34 1.4e-23 75.2 In-house 46-165 (343) Show / Hide
Range on Protein: 559-667
Range on HMM: 46-165/343
Sequence Identity: 34% (41 aa)

MKKNRVLQIIPYEFNRVIIP--------VKRGEENTDYVNASFIDGY----RQKDSY--IASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCA
. |||  .|.||| .||...        .|   .  ||.||...       ... ..  || |.||  |..||...| . ||..||.. | . ||| .||
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy

QYWPSdglVSYGDITVELKKEEE
.     || |||| |.   |   
rYWqe---gsydditvklaskwe

Phosphatase PTPRA.AA Subfamily.N_Nematode_eak.PD 552-704 25 2e-20 65.0 In-house 20-171 (281) Show / Hide
Range on Protein: 552-704
Range on HMM: 20-171/281
Sequence Identity: 25% (39 aa)

TGNLPANMKKNRVLQIIPYEFNRVIIPVKRgEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDG
..   ....|||..|.|.... | .   .  ..  |.||| ..       || .  .  . .  ||.|. | || .||.||  | . ||  .|.| ..  
vtarleavnrnrvvkivpqdrylvrltssq-lnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdkt

-LVSYGDITVELKKE-EECESYTVRDLLVTNtrENKSRQIRQFHFHGWPEVGIPS
..|| . || |.   . . . .| | ..    |.. ..  ....|| |. .|   
evlkyGildverkeyavkrniletrllilrk--GnethrvlhykvfGwtettlpk

Phosphatase PTPRA.AA Subfamily.N_Fungi_PTP1.PD 670-791 23 3.9e-16 50.7 In-house 196-341 (343) Show / Hide
Range on Protein: 670-791
Range on HMM: 196-341/343
Sequence Identity: 23% (34 aa)

SYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIA---------AVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLE----------
.  ||  ...   .  .. |.... |.....  . . .....            ..  ...   || |||||| |||||...|  .|.            
lnnnndltpvtaavsepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltk

-----RVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEY
    | |.    ....|. || ||  |||.|.|. |.|. .. |  
esrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfy

Phosphatase PTPRA.AA Subfamily.PTPDC1.PD 687-786 32 5.4e-09 27.6 In-house 132-222 (229) Show / Hide
Range on Protein: 687-786
Range on HMM: 132-222/229
Sequence Identity: 32% (33 aa)

RQIRQFHFHGWPEVGIPSDgKGMISIIAAVQKQQqQSGNhpITVHCSAGAGRTGTFCALSTVLE-RVKAEgildvfQTVKSLRLQRPHMVQTLEQYEFCY
||   |.  |... | .|  . .. |.  |.    . |.  |.||| || ||||   |   |   |..||      . .| .| .||. .|| || |.. 
rqgiyfynfglkDygvasl-eriLdivkvvdfal-eegk--iavHCHAGlGRtGvliacylvyakrltae------eaiklvrskrpksiqtreqvelve

K
.
e

Phosphatase PTPRA.AA Family.DSP.PD 683-782 20 1.9e-08 25.9 In-house 146-244 (387) Show / Hide
Range on Protein: 683-782
Range on HMM: 146-244/387
Sequence Identity: 20% (21 aa)

ENKSRQIRqFHFHGWPEVGIPSDGKGMISIIAAVQKQQqQSgNHPITVHCSAGAGRTGTFCALSTVLE-RVKAEgilDVFQTVKSLRlqrP-------HM
..|. .|. .. ....  . |.  . ....|  ..... .| .. . ||| || ||.|| ..   .   ....|   . .. |.| |   |. .. |...
ftkelgik-ylripidDhnapplenlfekaidfieegn-ds-kgvVlVHCkaGkgRsgtliiaYlmksegltle---ealdwvrskR---pgvitpnqgf

VQTLEQYE
|       
lkqlkdle

Phosphatase PTPRA.AA Subfamily.DSP23.PD 722-784 29 2.5e-07 22.6 In-house 63-120 (128) Show / Hide
Range on Protein: 722-784
Range on HMM: 63-120/128
Sequence Identity: 29% (18 aa)

QSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGildvfQTVKSLRLQRPHMVQTLEQYEFC
.  . ...|||  | |||||. |   | |.  | .     ...  .| .|.  ..| || .  
ekkeeavgvhcalGlGrtGtllacylvkeeglaad-----daiaevrkrrkGsietveqekav

Sequence
Name Sequence Type Origin Length Description Download
PTPRA.AA Protein None 802 None Fasta, JSON
PTPRA.NA RNA None 2406 None Fasta, JSON
PTPRA.AA.PD2_532-793 Protein Phosphatase Domain None 262 None Fasta, JSON
PTPRA.AA.PD1_240-503 Protein Phosphatase Domain None 264 None Fasta, JSON