Gene PTPRB
PTPRB
Species: Human
Alias: MGC59935, VEPTP, DKFZp686E2262, MGC142023, HPTP-BETA, PTPB, FLJ44133, PTPRB, R-PTP-BETA, DKFZp686H15164, HPTPB
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTPRB.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Fn3 | PTPRB.AA | FN3 | 328-410 | 19 | 4e-10 | 40.89 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 328-410 Range on HMM: 1-69/69 Sequence Identity: 19% (19 aa) PLPPAR---FGVSKEKTTST----SLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAG----SKYNIAITAVSG--GKRS | || . . |. .||| |... |.| ...|. ||. .|..| ..|.. ..||.| . .. PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Fn3 | PTPRB.AA | FN3 | 507-583 | 20 | 4.4e-07 | 30.76 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 507-583 Range on HMM: 1-69/69 Sequence Identity: 20% (19 aa) PMEVSN---LKVTNDGS-LT----SLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKELVPG----RLYQVTVSCV----SGEL | ..| |.||. .| | |. ..|..| . .| .. |.|| |...|..| || PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Fn3 | PTPRB.AA | FN3 | 595-677 | 21 | 1.7e-07 | 32.11 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 595-677 Range on HMM: 1-69/69 Sequence Identity: 21% (20 aa) PDKVAN---LEANNNGR-MR----SLVVSWSPPAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPG----RQYEVEVIVESGNLKNSE |. . | |.. . .. . |...||.|| .|| |||.|| .||. |....|| . . PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Fn3 | PTPRB.AA | FN3 | 685-764 | 18 | 7.4e-07 | 30.03 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 685-764 Range on HMM: 1-69/69 Sequence Identity: 18% (17 aa) PLAVLQ---LRVKHANET------SLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVPG----RKYMATVTSISGDLKNSS | .. |||.. ..| |... |. | |. .|.|.|.|| .| .|. ..|. . .. PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Fn3 | PTPRB.AA | FN3 | 861-939 | 12 | 2e-06 | 28.72 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 861-939 Range on HMM: 1-69/69 Sequence Identity: 12% (12 aa) PSSVSG---VTVNNSGRN-----DYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPG----RLYTVTITTRSG--KYEN |..... ..| . ... . ...|| .| . .|. . .. |.|| |..... ..| . | PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWK-PP--IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Fn3 | PTPRB.AA | FN3 | 949-1027 | 12 | 5e-06 | 27.19 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 949-1027 Range on HMM: 1-69/69 Sequence Identity: 12% (12 aa) PDKVQG---VSVSNSARS-----DYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPG----RLYSVTVTTKSG--QYEA |. ... ..|.. .. . ...|| . .|. ... |.|| |...|. ..| . | PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Fn3 | PTPRB.AA | FN3 | 1037-1116 | 14 | 5.3e-07 | 30.5 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 1037-1116 Range on HMM: 1-69/69 Sequence Identity: 14% (14 aa) PEPVKD---LTLRNRSTE------DLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPG----RQYKILVLTISG-DVQQS | |... |.... .. ....|. . .|. |..| |.|| .|.. | ..| |. .. PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Fn3 | PTPRB.AA | FN3 | 1125-1201 | 15 | 3.8e-08 | 34.32 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 1125-1201 Range on HMM: 1-69/69 Sequence Identity: 15% (14 aa) PSAVKN---IHISPNGAT-----DSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAG----EQYQIMIASV----SGSL |....| ..... ..| .|.|. |.| . .|. .|.. |..| .|.. .. | |. PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP---IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Fn3 | PTPRB.AA | FN3 | 1479-1557 | 20 | 3.5e-09 | 37.73 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 1479-1557 Range on HMM: 1-69/69 Sequence Identity: 20% (20 aa) PSPPSL---MSFADIANT------SLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPG----RSYQFNVKTV----SGDS |.||. .. |. .| |. ..|| || .... .| ||.|| |.| |. | | . PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWK-PP--------IVGYR------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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| Phosphatase | PTPRB.AA | PTPc | 1920-2183 | 38 | 9.1e-140 | 471.54 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 1920-2183 Range on HMM: 1-308/308 Sequence Identity: 38% (122 aa) LLSKEYEELKDVGRNQ---------SCDIALLPENR--GKNRYN-NILPYDATRVKLSNVDDD----PCSDYINASYIPGNNFRREYIVTQGPLPGTKDD ...|.|.|.... .. ||..| .|||| |||| .|..|| |||||.. ... ..||||||.||.| .....||.||||||.| .| GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED FWKMVWEQNVHNIVMVTQCVEK--------GRVKCDHYWPADQDSLYYGDLILQMLSESVLP-EWTIREFKICGEEQL-------DAHRLIRHFHYTVWP ||.|||.|..| ||| ..|.|| ||.||..||| . .. ||.......|| ..| ..|.|.|... .. . .| ..|.||| || FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP DHGVPETTQSLIQFVRTVRDYINRSPG-----------------AGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQ ||||||...|...|.|.||.. ..||. .||.|||||||.||||||.|.| ..||.. |||.. | .| .| .|||||.| DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQ YVYLHQCVRDVLR |.....|. .... YIFCYRCILEYIK |
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| Phosphatase | PTPRB.AA | Subfamily.RB.PD | 1922-2183 | 56 | 7.29999999999e-122 | 397.1 | In-house | 3-261 (261) | Show / Hide |
Range on Protein: 1922-2183 Range on HMM: 3-261/261 Sequence Identity: 56% (147 aa) SKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQ |.||||||.||..|... | ...|| |||..||||||..||||....|.. .|||||.|||| | .||||.||||||.| ||||.||||.... |||.|| seeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltq CVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQldaHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVH .||||..||..|||||... .|||. ...|.|. | ||.||||||. ... .| .|..|.| ||||||||.|..|..||||||..|.... ..|.||| lvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgke---krkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvH CSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLR ||||||||||||||||.||.....| ||..| |..|| .|...|||| ||...|.|. |.|. CsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldlle |
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| Phosphatase | PTPRB.AA | Y_phosphatase | 1945-2180 | 45 | 7e-116 | 396.08 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 1945-2180 Range on HMM: 1-243/243 Sequence Identity: 45% (112 aa) NRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGN-NFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGR-VK-CDHYWPA--DQD |. |||| .|..|| |||||. ...|. ||||||.||.|. . ..||.||||.| | .|||.|||.|... |||...|.|.|| .| |..||| ... NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ SLYYGDLILQMLSESVLPEWTIREFKICGEEQ-LDAHRLIRHFHYTVWPDHGVPET-TQSLIQFVRTVRDYINRSPGAG--PTVVHCSAGVGRTGTFIAL .. |||.. . || ..|..|.|.|... . . | ..|.||| ||||||||. ..|...|.| || . . .|..| |.|||||||.||||||.|. PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-NPDHGCPPIVVHCSAGCGRTGTFCAI DRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRD | ..||.. ...|||...| .| .| .||||| ||....||. . DIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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| Phosphatase | PTPRB.AA | Subfamily.R_Anemone_2.PD | 1921-2182 | 47 | 1e-96 | 314.9 | In-house | 2-261 (262) | Show / Hide |
Range on Protein: 1921-2182 Range on HMM: 2-261/262 Sequence Identity: 47% (123 aa) LSKEYEELKDVGRN-QSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMV ||.|||.|. . .. ... || | |. ||||.|||.|| |||||....... ||||||.||.|.. ...|| ||.||| | .|||.|||||| |||. lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml TQCVEKGRVKCDHYWPADQdSLYYGDLILQMLSESVLPEWTIREFKICGEEqLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRdYINRSPGAGPTV ||..|.|..|...||| .. | ||.| .. .| | ....|.||. .| ...| .| |||||||.|||| . ||...||.|. ......||||.|| tqeeergkakvhryWPskg-srsygklvvelkeevelsdyvlrsfkvkrte-eeeerqvrqfhytsWpdegvpesgaslldlvrqve-kaqqesgagpiv VHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVL ||||||||||.|||.| .|... ||... |. || .| ||||.||..... . . | vhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal |
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| Phosphatase | PTPRB.AA | Subfamily.N_Choan_1.PD | 1923-2182 | 43 | 3e-90 | 293.5 | In-house | 4-261 (262) | Show / Hide |
Range on Protein: 1923-2182 Range on HMM: 4-261/262 Sequence Identity: 43% (113 aa) KEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQC .|||.|...|..... . .||. ||||.|| |||||||... ... .|||||...|| . .|||.||||.| . ..||.|||||.|. |||||. eeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtre VEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKIcgEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGaGPTVVHC .|.|..|| .||| .. .| .||.....|||. ... |.||. |.. .| .....|| |||||||.||. |..| . |. . ... | |.|| ieagklkChryWPdenselklgdvtvkslseeekktyierkfkl--eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk-aplvihC SAGVGRTGTFIALDRILQQLDSKDSV-DIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVL |||||||||.|||||.......| .. |. |..|| .| |||| || .....| |.| saGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal |
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| Phosphatase | PTPRB.AA | Subfamily.R_Sponge_2.PD | 1932-2181 | 40 | 1.1e-87 | 285.2 | In-house | 12-260 (262) | Show / Hide |
Range on Protein: 1932-2181 Range on HMM: 12-260/262 Sequence Identity: 40% (101 aa) GRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNvDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCD . |..|| |.|| ||||...||||| .||.|.. |. . |||||||.. | . | ||.|||||. | .|||.||||..|.|||.|. .|.|. || .|| etefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekca HYWPAD-QDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYiNRSPGAGPTVVHCSAGVGRTG | ... ||. .. .|. |....||..|.. |.. . .. ...||...||.|.||... ||......|. .. | .. .|.||.||||||||| kYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlra-qkksgnkaitvvCsdgvgrtG TFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDV ||| .|..|. ...|.. ...|| .|. .||.. |||..|. . .. tfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalley |
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| Phosphatase | PTPRB.AA | Subfamily.R_Anemone_1.PD | 1922-2182 | 38 | 4.9e-83 | 270.1 | In-house | 3-257 (258) | Show / Hide |
Range on Protein: 1922-2182 Range on HMM: 3-257/258 Sequence Identity: 38% (101 aa) SKEYEELKdVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQ ..|...|| ..... ..| .||. ||||..|...| .|| |.....|. ||||||||. . . .|..|.||.||. | .|||.|||.... |||.|. aaefqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtn CVEKGRVKCDHYWPAdqDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLdAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYinRSPGAGPTVVH .|. || .||| . ||.| ... .. | ...||.... ... .| ....|.|||||.|||..........|.|.. . .|| | ||| liegekkkchqYwPd--stekygelrvslrkkevfadyiirtlvlskkket-eerevvqyhftvWpdkgvPqyatavLglrrkvqks--slagarpvvvh CSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVL |||||||||.|...| .|.|. .. |||. .|. .| .| |||||. |||..|. | . | CsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal |
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| Phosphatase | PTPRB.AA | Subfamily.RA.PD | 1922-2180 | 39 | 5.4e-83 | 269.8 | In-house | 3-263 (266) | Show / Hide |
Range on Protein: 1922-2180 Range on HMM: 3-263/266 Sequence Identity: 39% (102 aa) SKEYEELKDVGRN-QSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVT .|...| | . .....| ..||. |||. .||||| .|| ||... ..|||||||.| | . . ..| .|||. | .|||.|.|||.. |||.|. eeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmlt QCVEKGRVKCDHYWPaDQDSLYYGDLILQMLSESVLPEWTIREFKIC---GEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYiNRSPGAGP |... || ||| |. .. ||.. ... | || ..|.|.| . . . ...||.| ||.| ||. ||| ... ...... |. .. .. | | elkerkeekcaqywp-deGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkkl-qqqsanhp TVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRD ||||||||||||||.|| .|... ... .|...||. ||| | .||||. ||..... ... ivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle |
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| Phosphatase | PTPRB.AA | Subfamily.RG.PD | 1921-2180 | 40 | 7.2e-81 | 262.8 | In-house | 2-261 (264) | Show / Hide |
Range on Protein: 1921-2180 Range on HMM: 2-261/264 Sequence Identity: 40% (107 aa) LSKEYEELKDVGRNQ-SCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMV |....||.. . .. ... . .||. |||. ||.... .|||||.. . .|||||||| | . .|||||||||. | .|||.|.||.|.. |||. leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml TQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAH-RLIRHFHYTVWPDHGVPETTQSLIQFVRTVrdYINRSPGAGPT |. .|||| ..| |||.....| ...| ...||...| . |.|.| . .. . . | .|..||| |||.|.|| | . ||. .. |||. tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkke--eaankeeaGPi VVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRD |||.||||||.||.|||| .||||.....|..|. .. .|..| ..|.|| |||.... . . vvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydalle |
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| Phosphatase | PTPRB.AA | Subfamily.RK.PD | 1922-2179 | 38 | 9.5e-81 | 262.2 | In-house | 3-263 (267) | Show / Hide |
Range on Protein: 1922-2179 Range on HMM: 3-263/267 Sequence Identity: 38% (101 aa) SKEYEEL---KDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDpCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVM .|.| | .. ..||||....|| |||...||.|| ..|.| ||.| ||||||..| . . ...|||||||. | |||..|...| |||. keefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivm VTQC-VEKGRVKCDHYWPADQDsLYYGDLILQMLSESVLPEWTIREFKICG-EEQLDAHRLIRHFHYTVWPDH-GVPETTQSLIQFVRTVRDYINRsPGA |. ||.||||| .||| | . |||. ..... ... . .| |... . ...|..|.|... ||.. .||. .||....| | . ..| lteldvevgrvkClkyWPedte-vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee-eee GPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVR ..||||.|| ||.|||||.| .|. .. .. ||.. ||..|| ..| ||.|| ||..... . GrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvil |
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| Phosphatase | PTPRB.AA | Subfamily.R_Ecdysozoa.PD | 1921-2180 | 40 | 1.5e-78 | 255.0 | In-house | 2-266 (269) | Show / Hide |
Range on Protein: 1921-2180 Range on HMM: 2-266/269 Sequence Identity: 40% (106 aa) LSKEYEELK-DVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMV | .|||.|. . ..|. .. || ||||..| ..| |||||... . |||||||.| | . ....|. |.|. .| .|||.|..||.|. |||. leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml TQCVEKGRVkCDHYWPADqDSLYYGDLILQMLSESVLPEWTIREFKIC--GEEQLDAHRLIRHFHYTVWP-DHGVPETTQSLIQFVRTVRDYINRS---P .. || | |..||| . | |||.. .. ||. ....|||... .|| ....| . ..|| |. | |||....|..... ||.. . . snlteknrk-cakyWpie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsg GAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRD .| ||||||||||.|.|.||| .|||| |.|||. |..|| .|.|| |||.|.. . | srsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad |
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| Phosphatase | PTPRB.AA | Subfamily.N9.PD | 1921-2178 | 39 | 1.6e-78 | 255.3 | In-house | 2-270 (275) | Show / Hide |
Range on Protein: 1921-2178
Range on HMM: 2-270/275
Sequence Identity: 39% (107 aa)
LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVT
|||||..... . . . |. | ||||...| || |||||...|.|..||||||... | . .. .| |||||. | .|||.|||||.| |||.|
lskeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmtt
QCVEKGRVKCDHYWP-ADQDSLYYGDLILQMLSESVLPEWTIREFKICGEeQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYIN---------
..||.||.|| .||| ...| .||| .. .. | ....| ..| . . .| . || .. |||.|||....||......||..
rvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknv-kteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde
--RSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCV
. | |||||||.|||||||.|| |..|.... ||. .|. || | ...||. ||.. ...|
skghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylav
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| Phosphatase | PTPRB.AA | Subfamily.N6.PD | 1921-2179 | 38 | 7e-77 | 249.9 | In-house | 14-291 (295) | Show / Hide |
Range on Protein: 1921-2179 Range on HMM: 14-291/295 Sequence Identity: 38% (107 aa) LSKEYEELK--DVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNV-DDDPCSDYINASYI--------PGNNFR-----REYIVTQGPLPGTKDDF ...|.|||. .. .. |.. . .||. ||||.||||.| |||.|... .. | ||||||.|| |.|. ..||.|||.|. | || fweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdF WKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRT |.|||..| . |||.|. ||.|. || .|||. ... .|.. ....||. ..|.|||... ... . .| |...|...|||||||. .. ...|.. WrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfled VRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKD---SVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVR |. .. |||.|||||||.||||||| .| .|... .. .||. ...|.| .| .|||| || .. ..|. vnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq |
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| Phosphatase | PTPRB.AA | Subfamily.N12.PD | 1936-2182 | 41 | 2.7e-76 | 247.6 | In-house | 23-269 (270) | Show / Hide |
Range on Protein: 1936-2182 Range on HMM: 23-269/270 Sequence Identity: 41% (103 aa) SCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWP | . . .||. |||| .||||| .||.||. .... ||||||..| | . . ||| .||||| | ||||.|.||.||. .||. . || |. ||..||| steagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWp AD-QDSLYYGDLILQMLSESVLP-EWTIREFKICGEeqlDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINrsPGAGPTVVHCSAGVGRTGTFI ...| .|.. ... .| . ...|| .|. . ...| .. |||| |||||||....||......||.. . .| ||||||||||||| || eegeeelefgefevtleeekavdddflirtLkveaq---kesrkvyqfhytaWPDhgvPssaksllelielvrelqe--sedaPlvvhCsaGvGrtGtii ALDRILQQLDSK---DSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVL .| . ..| .. ...|.. | .|| .|. .|||. ||......| ... aidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv |
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| Phosphatase | PTPRB.AA | Subfamily.N3.PD | 1924-2179 | 41 | 2.3e-74 | 241.2 | In-house | 5-257 (261) | Show / Hide |
Range on Protein: 1924-2179 Range on HMM: 5-257/261 Sequence Identity: 41% (107 aa) EYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDdpcsDYINASY----IPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMV ..||| . ....| .||| |||| .|||||||||||.. . |||||.| ||.... ||.|||||. | |||.|||||... |||. qfeelyrkkpglaisaarkpenlaknryrdilpydatrvklkeset----dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivml TQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQlDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYinRSPGAGPTV |. ||.||||| .||| .|.| .|.. ... .|. .. .||. .. .|. . .| | .. |. |||||||. ......||..||.. || |.| ttlverGrvkChqyWPetedelefgefsvrcekedetksyvlrelvlkdket-keerkilqlqylaWpdhgvPddsadflefvervrkl--rsgkeePvv VHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVR ||||||.|||| .|.|. |. ......| . |. .| | .|||. || .. ... vhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeail |
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| Phosphatase | PTPRB.AA | Subfamily.N13.PD | 1922-2182 | 39 | 1.3e-73 | 239.1 | In-house | 3-258 (259) | Show / Hide |
Range on Protein: 1922-2182 Range on HMM: 3-258/259 Sequence Identity: 39% (104 aa) SKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDdpcsdYINASYI--PGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMV ..|..||... ..|... ||. |||| |.||||.|||||.. |||||.| | .. . |||..||||| | .|||.|||||... |.|| aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamv TQCVEKGRVKCDHYWPADQDS--LYYGDLILQMLSESVLPEWTIREFKICGEeQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINrspGAGP |. .|||.|||. ||| ... .. | ...| | ....|.... . . | . |.... ||||||| ....|.|||. || . ||| tlekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkds-esgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt---dagP TVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVL |||||||.||.|..|..| .|. .. . ..|. |..|| | .|||. ||.. .. . .|| ivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl |
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| Phosphatase | PTPRB.AA | Subfamily.N_Choan_2.PD | 1937-2180 | 39 | 1.2e-70 | 229.1 | In-house | 13-263 (266) | Show / Hide |
Range on Protein: 1937-2180 Range on HMM: 13-263/266 Sequence Identity: 39% (97 aa) CDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGN-NFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWP .| |. ||||.||| ||||.|.....|. . |||| |..| . ...|| ..|||| | .||.|.||..|. |||.|. .|||| ||. |||| eaiPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWp ADQDS-LYY--GDLILQMLSESVLPEWTIREFKIcgEEQLDaHRLIRHFHYTVWPDHGVPETTQ------SLIQFVRTVRDYINRSPGAGPTVVHCSAGV .... . . |.. |||. . ... .. |.. . .| ..||.|. |||||||.....|.. .|.|| . |.|..||||||||||||.| aepkekvkladgkikvlalseekeegyiltrlrl--ekkge-trrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGv GRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRD |.| ... |... .||. ...|| .|. .||. || .|.. |.. gRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavve |
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| Phosphatase | PTPRB.AA | Subfamily.N5_RR.PD | 1926-2178 | 36 | 1.8e-69 | 225.4 | In-house | 4-260 (265) | Show / Hide |
Range on Protein: 1926-2178 Range on HMM: 4-260/265 Sequence Identity: 36% (95 aa) EELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKL-SNVDDDPCSDYINASYIPGNNFR-REYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCV .| .. | | . .. . ||||..||| . .|| | |. .|. |.|||| || | . . . |. |||||| | .|||.|.....|. |||.|. keflelPlnfsqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklk EKGRVKCDHYWPADQDS---LYYGDLILQMLSESVLPEWTIREFKICGEEQldAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGA-GPTV |. | || .|.| ..| |||. ... . ....|.. . |. .| . |. || |||| .|. ...|...|. |.. ... .| | eanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkyler--versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvv VHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCV ||||||.|||| ||| . ..||. . ||. . | .|||.| ||||. || ..|. . vhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihral |
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| Phosphatase | PTPRB.AA | Subfamily.N1.PD | 1935-2172 | 41 | 1.5e-64 | 209.4 | In-house | 18-257 (268) | Show / Hide |
Range on Protein: 1935-2172 Range on HMM: 18-257/268 Sequence Identity: 41% (99 aa) QSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDdpcsDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYW .. | ||||||.||| .. ||| .|.|| . | |||||| . .. .|.||.|||||| | | ||.|||||| . ..|. ..|||...|| .||| letreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqyw PADQDS--LYYGD--LILQMLSESVLPEWTIREFKICGEEQlDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTG .... |.. . | ....|| . ... | ... |. . | | ||||| ||| ||||. .....|. .||. |.||.|.|||||.||.||. pqeeeeaellleetklkvkliseerksyflvrlleLedlet-qetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsg TFIALDRILQQLDSKDS---VDIYGAVHDLRLHRVHMVQTECQYV .| .| ... .. ||| . .|| .|| ..|| | tlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLr |
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| Phosphatase | PTPRB.AA | Subfamily.RC.PD | 1921-2179 | 32 | 3e-64 | 208.4 | In-house | 2-284 (288) | Show / Hide |
Range on Protein: 1921-2179 Range on HMM: 2-284/288 Sequence Identity: 32% (91 aa) LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKL-------------------SNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTK | |...| | .. || .||. |||| ..|||| ||.| ...| . |.|||||.| . . || .|||| | leaefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketv DDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWpaDQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAhRLIRHFHYTVWPDHGVPETTQSLIQF ||||.|..|. |. |||.|.. | | || .|| .. |||. ... . .....| ... . . |. | . .. |||.....|| . |.... ddfwrmiferkvkvivmltelkeGdrekcaeyw--eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkds-revtqiqytswsveqlpeepkellkl VRTVRDYI---NRSP-----GAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVR . |.. . ..| ..| .|||..|..|||.||||. .|. |.... ||... | || | ||..|||..|.. . iqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlv |
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| Phosphatase | PTPRB.AA | Subfamily.N14.PD | 1923-2178 | 34 | 7.7e-60 | 193.8 | In-house | 4-270 (275) | Show / Hide |
Range on Protein: 1923-2178
Range on HMM: 4-270/275
Sequence Identity: 34% (94 aa)
KEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDpCSDYINASYIP--GNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVT
.|||... . .. | |||| |||....|||. .||.|| .. ..||||| | .|.|||.||||. | |||.|||||.|. |||.|
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlt
QCVEKGRVKCDHYWPAD---QDSLYYGDLILQMLSESVLPEWTIREFKICGeEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTV---RDYINRSPG
. |.|. |. .|.| . .... .| .. . . . . .|. .| . |. || |||||||| .....|.. | | |..
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkh-lpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseve
-----AGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCV
| .||||||||||| | | ... |. ...|| ... || | ..||| .|| .... .
svkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvl
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| Phosphatase | PTPRB.AA | Subfamily.RN.PD | 1921-2179 | 37 | 1e-54 | 176.9 | In-house | 2-260 (264) | Show / Hide |
Range on Protein: 1921-2179 Range on HMM: 2-260/264 Sequence Identity: 37% (97 aa) LSKEYEELKDVGRNQ-SCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRR-EYIVTQGPLPGTKDDFWKMVWEQNVHNIVM |.||.| |.. .. ....| ..| |||....|||| .||||.. . ||||||| | .. |. || |||||. | |||.||||| | ||. lekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivn VTQCVEKGRVKCDHYWPADQDSLYyGDLILQMLSESVLPE-WTIREFKICgEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYInRSpGAGP .|. |.| .|..||| . ..| . ....|| . . . .| | . . | . | . ||. ||..||| ...||..|| | | . | ltrleeegvkqckrywpdeGsevy-hiyevhlvsehiwcddylvrsfylk-nlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksy-rG-rscp TVVHCSAGVGRTGTFIALDRILQQLD-SKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVR |||||.|.||||..|..| .|..| .|| .. || | ..|.|. |. . ..| ivvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltava |
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| Phosphatase | PTPRB.AA | Subfamily.N20.PD | 1942-2183 | 41 | 6.6e-54 | 174.5 | In-house | 23-257 (257) | Show / Hide |
Range on Protein: 1942-2183 Range on HMM: 23-257/257 Sequence Identity: 41% (101 aa) LPENRGKNRYNNILPYDATRVKLSNvdddpCSDYINASYIPGNNFRREY--IVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPAD-Q | || |||| .|||||.||| | . . |||||||| | || | ||||| | ||||.|| |.| | |.|. .| | .|||||| . qpsnreknryrdilpydstrvplgk-----skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislk DSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHrLIRHFHYTVWPDHGVPETTQSLIQFVRtvrdYINRSPGAGPTVVHCSAGVGRTGTFIALDRI | . . . .| . || |.. . .| ......| ||||| | ...|.|...| | .| .|| |||||||.|||| |...| .. kplelkhfrvflenyqilqyfiirmfqvvekstgtsh-svkqlqftkwpdhgtpasadsfikyir----yarkshltgpmvvhcsagigrtgvflcvdvv LQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLR . . |..| | ..| .| ||||. || . .. | .||| fcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevlr |
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| Phosphatase | PTPRB.AA | Subfamily.N_Nematode_1.PD | 1921-2178 | 31 | 4.5e-52 | 168.3 | In-house | 2-260 (265) | Show / Hide |
Range on Protein: 1921-2178 Range on HMM: 2-260/265 Sequence Identity: 31% (83 aa) LSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNvdDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVT | .|...|| .... . ....||||... | .||||.. . |||| | |. . .| .|.|| | .||| || ..| .|||. lrdefralkkfndeekvkafkeaqeadknrykdvgcldknrvklae--eplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlc QCVEKGRVKCDHYWPADQ-DSLYYGDL----IL--QMLSESVLPEW-TIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRdyinrs ...|||..|| .|.|| . . | . . .. .. .. . .. .|.. .. | . .|..|...| |||.|||.. . .... || . kliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavr------ PGAGPTVVHCSAGVGRTGTFIALDRILQQLD-SKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCV ||.|||||||.||||| .|.. ||..| .| |. |...| .| . .||. ||...|. . gskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvl |
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| Phosphatase | PTPRB.AA | Subfamily.N23.PD | 1952-2177 | 34 | 7.2e-52 | 167.9 | In-house | 109-344 (350) | Show / Hide |
Range on Protein: 1952-2177 Range on HMM: 109-344/350 Sequence Identity: 34% (80 aa) NNILPYDATRVKLS-NVDDDPCSDYINASYIPGN-NFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS-LYYGDLIL .. | .|||| . .|||||.|. ..|.||||.. | |||.||||| . |||.|. ||... |||.|||.|...||| . . | tpdsrhdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrv QMLSESVLPEWTIREFKICGeEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYI-----NR--SPGAGPTVVHCSAGVGRTGTFIALDRILQQ . ..| | ... .. .. ||. |.|.| |...|||. ..|..|. |. . . . | | ..|||||||||||| . ....|. . slkslrssegwiervlhlqh-ndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaire LDSKDSV-DIYGAVHDLRLHRVHMVQTECQYVYLHQC . . .| |. || | .|||.. .. | . ltagngiiniprvvrrlrqqRkymvqkkvilkklyea |
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| Phosphatase | PTPRB.AA | Subfamily.N_Nematode_4.PD | 1934-2180 | 29 | 2.5e-51 | 165.9 | In-house | 15-261 (264) | Show / Hide |
Range on Protein: 1934-2180 Range on HMM: 15-261/264 Sequence Identity: 29% (75 aa) NQSCDIALLPENRGKNRYNNILPYDATRVKLSNVddDPCSDYINASYIPGNnFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHY . .. .| ||||..|| |.||| | | || ||| ||.. . .|| |||||. | .||| ||... ...||. . .|.| || |. ppnvtasaseknsdknryadilcidetrvvlknr--dpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcary WPADQDS-LYYGDLILQMLSES--VLPEWTIREFKICGEE-QLDAHR---LIRHFHYTVWPDHGVPETTQSLIQFVRTVRDyiNRSpgAGPTVVHCSAGV | ... .|. .... . |. . .. .|. . | ..|| ...|.... |.|.|......|.. ..|.. ... .| ||||||||||| ypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkk--ekPivvhcsaGv GRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRD |.. .| ... . .... |..|| |.. ||.. |...| .. . GrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvlie |
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| Phosphatase | PTPRB.AA | Subfamily.R_Nematode_2.PD | 1945-2176 | 31 | 5.1e-49 | 158.2 | In-house | 29-254 (261) | Show / Hide |
Range on Protein: 1945-2176 Range on HMM: 29-254/261 Sequence Identity: 31% (74 aa) NRGKNRYNNILPYDATRVKLsnVDDDPCSDyINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQ-DSLYY .. |.||... . |.|. . |. .. | | ..| .. . .|.||||| |..||| || ..| .|||..|.|||. ||..|.| .. ..| | pkdkhRypdvPCkpetavev--ivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldl GDLILQMLSESVLPEWTI--REFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINrspgagPTVVHCSAGVGRTGTFIALDRILQQ . ....|. . . | | .|. ... | | ..|. |. |||.|||.. . | . . |.. . | |||||||.|||..||. . . ... grfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek------PivvhCsaGiGRtmafigteylare LDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQ .... . |...|| || . .||| |. .|. veadptieltealkelrehRwkgiqtesqlywltl |
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| Phosphatase | PTPRB.AA | Subfamily.N_Nematode_6.PD | 1921-2182 | 33 | 2.6e-48 | 156.0 | In-house | 2-252 (253) | Show / Hide |
Range on Protein: 1921-2182 Range on HMM: 2-252/253 Sequence Identity: 33% (89 aa) LSKEYEELKDVGRNQSCDIALlpENRGKNRYNNILPYDATRVKLSnvdDDPcSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVT | |||.. . . .... | ... .|||.|| .||.|.||. ||. || |... | .|.||.|| || ..||||. . |. |||. lkkeykdspneaseseatafl--kfkdrnrytniqCcdagrlkla---dde-dfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlc QCVEKGRVKCDHYWPAD-QDSLYYGDLILQMLSESVLPE-WTIREFKICGEEQlDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYinrspgAGPT . ||||. |. .| . |. ...| .. . . . . | | . | . ...|.|. |||||||.. .| .... |.. | elvekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkag-deevivkhihWanWPdhGvPdsflsalrllsvvkkd------kkPi VVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVL |||||||||||||.. . ||. | . | .. . || |..|||| ||.| ..|| . | vvhCsaGvGrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvleyl |
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| Phosphatase | PTPRB.AA | PTPc_motif | 2077-2180 | 44 | 2.5e-44 | 154.53 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 2077-2180 Range on HMM: 1-92/92 Sequence Identity: 44% (49 aa) LIRHFHYTVWPDH-----GVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQY ..|.||| |||| |||| .|...|.| ||. |.|||||||.||||||.|.| ..|| |||.. |. .| .| .||||| || TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQY VYLHQCVRD .....|. . IFCYRCILE |
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| Phosphatase | PTPRB.AA | Subfamily.N_Nematode_5.PD | 1922-2178 | 25 | 6.7e-43 | 138.1 | In-house | 3-253 (258) | Show / Hide |
Range on Protein: 1922-2178 Range on HMM: 3-253/258 Sequence Identity: 25% (65 aa) SKEYEELKDVGRNQScDIALLPENRGKNRYNNILPYDATRVklsNVDDDPcSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQ ..|.|.|. . |. . .| |||.... .|.||| .. |.. ..|||||.| .......|.|| ||| |. |||.|| ..... .|.... ktefeklaslkpnke-tckafeknlkknrskdvkilDetrV---kltded-dsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllve CVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEW-TIREFKICGEEQLDAhRLIRHFHYTVWPDHGVPETTQSLIQfvRTVRDYINRSPGA-GPTV | . ... . .| |..|... .. | . . ... |.. .. .... |.||... ||. .. .|. |.. ... . |. |.|| deelketavsffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcses-vfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvv VHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCV ....|.||.|||..|. . .||... ...| . .| |...|.. .||......| vvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaav |
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| Phosphatase | PTPRB.AA | Subfamily.R_Nematode_3.PD | 1923-2182 | 22 | 1.3e-33 | 107.8 | In-house | 4-266 (267) | Show / Hide |
Range on Protein: 1923-2182 Range on HMM: 4-266/267 Sequence Identity: 22% (59 aa) KEYEELKDVGRNQSCDIAllpENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNfRREYIVTQGPL--------PGTKDDFWKMVWEQNVH |..|... ...... .. .. ..|. ... . .|||.| . .|.|.|... .| . |.||.|.| . ||.|. ...|...||. . || kafekiaklakknatsls---kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpn-glklIltqsPqkkdkekkkkstieKfwwmieqekve NIVMVTQCVE---KGRVKCDHYWPADQD-SLYYGDLILQM--LSESVLPEWTIREFKIcGEEqLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDY .. || .|.| ..| .| ... .. .. . . |.... |. ..| .|. |.....||....... .. |. . | |||| qvvmlcdfveedgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfe-kkkeftvthllykgWkelnapeepkealelikfveks INrspgagPTVVHCSAGVGRTGTFIALDRILQQLD-SKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVL |.|..|..|. | . | . ||...|....|| .| . .||| .. .. .. ..| kt------pvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkll |
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| Phosphatase | PTPRB.AA | Subfamily.N_Nematode_egg.PD | 1922-2179 | 26 | 2.8e-30 | 97.0 | In-house | 3-253 (257) | Show / Hide |
Range on Protein: 1922-2179 Range on HMM: 3-253/257 Sequence Identity: 26% (68 aa) SKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQ ...| |. . ..| |. ... | | . . . .|||| |.| | .. |. . |.|..| || |..|||.||....|. |||.| errfeilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmlts CVEKgrVKCDHYWP-ADQDSLYY--GDLILQMLS--ESVLPEWTIREFKICGEEqlDAHRLIRHFHYTVwpdhGVPETTQSLIQFVRTVRDYinrspgAG .| .|..||| |...|| . | | .. | . | ... ..|. | . | .. |. . | | .. .| .|. . |. akes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgd--deelflehwqgdv----nylsdvysplrvlrklrnl------sk PTVVHCSAGVGRTGTFIALDRILQQLDS--KDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVR ||.. || ...|..|.. | .| . |||||.| |.. .|..... | pvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl |
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| Phosphatase | PTPRB.AA | Subfamily.N_Fungi_PTP1.PD | 1945-2036 | 40 | 3.8e-25 | 79.9 | In-house | 45-150 (343) | Show / Hide |
Range on Protein: 1945-2036 Range on HMM: 45-150/343 Sequence Identity: 40% (41 aa) NRGKNRYNNILPYDATRVKLSNVD--------DDPCSDYINASYIPGN------NFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKC ||||.|||||. .|||| . .|||||.|. . | || ||.||| | |||.|.. . .|. |...|. || .. ||..| lfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekc DHYWPA |. yrYWqe |
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| Phosphatase | PTPRB.AA | Subfamily.N_Nematode_eak.PD | 1935-2182 | 23 | 6.7e-21 | 66.2 | In-house | 16-280 (281) | Show / Hide |
Range on Protein: 1935-2182 Range on HMM: 16-280/281 Sequence Identity: 23% (62 aa) QSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPcSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYW .| . |. .|| .|.|.| |.|.. .. ||||| . .. |.||.| . ||.|| ||.||.. . ||.. | | |.| . lsirvtarleavnrnrvvkivpqdrylvrltssqlnr-dGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyf PADQDSLYYGDLILQMLSESVL-PEWTIREFKICgeEQLDAHRlIRHFHYTVWPDHGVPETTQ------------------SLI-QFVRTVRDYINRSPG . | || | .. . .| | ... ..|| . |... | . .|. . |.. || | | .. pdktevlkyGildverkeyavkrniletrllilr--kGnethr-vlhykvfGwtettlpkyedflalrkvmkevGvlllivmksallrstlkkyihtpps AGPtVVHCSAGVGRTGTFIALDRILQQLDSK--DSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVL .. | |.|.|. .| ... .|.| .. .. . .|.| | .. |. .... | | | fap-iiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl |
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| Phosphatase | PTPRB.AA | Subfamily.N_Fungi_PTP1.PD | 2078-2179 | 25 | 1.2e-14 | 45.5 | In-house | 215-339 (343) | Show / Hide |
Range on Protein: 2078-2179 Range on HMM: 215-339/343 Sequence Identity: 25% (32 aa) IRHFHYTVWPDHGVPETTQSLIQFVR---------TVRDYINRSpGAGPTVVHCSAGVGRTGTFIALDRILQ---QLD--SKDSV----------DIYGA . .... |.| .. .|..| . . . ... . . | .||||||||||||...|| .|. |. |.|. | vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldna-rsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisii VHDLRLHRVHMVQTECQYVYLHQCVR | || .|. |||. |......... vnelrkqrismvqnldqfifiYeall |
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| Phosphatase | PTPRB.AA | Family.DSP.PD | 2009-2190 | 16 | 4.2e-12 | 37.4 | In-house | 129-253 (387) | Show / Hide |
Range on Protein: 2009-2190 Range on HMM: 129-253/387 Sequence Identity: 16% (30 aa) WEQNVHNIVMVTqcvekgrvkcdhywpadqdslyygdlilqmlsesvlpewtirefkiCGEEQLDAHRLIRHFHYtVWPDHGVPETTQSliqFVRTVRdY | .| || .| ....| . |.. .. ..||..| . |.. .. .| kelgvtkivnlt----------------------------------------------ddkpqftkelgikylri-pidDhnapplenl---fekaid-f INRSP-GAGPTVVHCSAGVGRTGTFIALDRILQ-QLDSKDSVDIYGAVHdlrlhRvHMVQTECQyvYLHQCVRDVLRARKLRSE . .. | .||| ||.||.|| |. .. . .| ....| . .. . .... . . .|.| . . .|..|| ieegndskgvVlVHCkaGkgRsgtliiaYlmksegltleealdwvrskR-----p-gvitpnqg--flkqlkdlekeklkvsse |
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| Phosphatase | PTPRB.AA | Subfamily.PTPDC1.PD | 2081-2176 | 25 | 4.7e-08 | 24.1 | In-house | 137-222 (229) | Show / Hide |
Range on Protein: 2081-2176 Range on HMM: 137-222/229 Sequence Identity: 25% (24 aa) FHYTVWPDHGVPeTTQSLIQFVRTVRDYInrspGAGPTVVHCSAGVGRTGTFIALDRILQQldskdSVDIYGAVHDLRLHRVHMVQTECQYVYLHQ |. ..|.||. . ..... |. | . | . ||| || |||| || . .. .. |.. .| .| . .||| ... fynfglkDygva-sleriLdivkvvdfal----eegkiavHCHAGlGRtGvliacylvyak-----rltaeeaiklvrskrpksiqtreqvelvee |
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| Phosphatase | PTPRB.AA | Subfamily.PTEN.PD | 2084-2152 | 29 | 1.5e-06 | 19.1 | In-house | 65-133 (305) | Show / Hide |
Range on Protein: 2084-2152 Range on HMM: 65-133/305 Sequence Identity: 29% (20 aa) TVWPDHGVPeTTQSLIQFVRTVRDYINRSPgAGPTVVHCSAGVGRTGTFIA--LDRILQQLDSKDSVDIYG || | | . | ..|..| ... . .||| || ||||. |. | ... . .....||. ypfdDhnpp-tleLleeivedvdkwLkedk-snVvavHCkaGkGRtGvmicayLlksgikksadealaiyd |
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| Phosphatase | PTPRB.AA | Subfamily.TPIP.PD | 2088-2136 | 32 | 2.8e-06 | 18.5 | In-house | 12-58 (245) | Show / Hide |
Range on Protein: 2088-2136 Range on HMM: 12-58/245 Sequence Identity: 32% (15 aa) DHGVPETtQSLIQFVRTVRDYINRSPGAgPTVVHCSAGVGRTGTFIALD || ||. . |..| . |...... . ..|| | ||||| . dhnvPtl-eelvvftkevkewlakdlen-vvaihckGGkgrtGtivcal |
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