• Phosphatome.Net

Gene PTPRH

PTPRH
Species: Human
Alias: FLJ39938, SAP1, MGC133058, MGC133059, PTPRH
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RB
Protein domain

Protein domains of PTPRH.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Fn3 PTPRH.AA FN3 30-109 21 1.6e-10 42.17 SMART 1-69 (69) Show / Hide 
Range on Protein: 30-109
Range on HMM: 1-69/69
Sequence Identity: 21% (20 aa)

PNPGRN---LTVETQTTS------SISLSWEVPDGLDSQNSNYWVQCTGDGGTTETRNTTATNVTVDGLGPG----SLYTCSVWVEKD-GVNSS
| | .|   |.|.  |..      |..|||. |        .|.                   .||.|| ||    . |. .|... . .. ..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR-------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 PTPRH.AA FN3 119-198 23 5.3e-11 43.79 SMART 1-69 (69) Show / Hide 
Range on Protein: 119-198
Range on HMM: 1-69/69
Sequence Identity: 23% (22 aa)

PNPVRN---LRVEAQTNS------SIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAHTNITVDGLEPG----CLYAFSMWVGK-NGINSS
| |..|   |||.. |..      |. |.|. |           |.|.                ||.||.||      | |. ..   |.  ..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----------IVGYR---------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 PTPRH.AA FN3 208-287 21 3.4e-09 37.78 SMART 1-69 (69) Show / Hide 
Range on Protein: 208-287
Range on HMM: 1-69/69
Sequence Identity: 21% (20 aa)

HNPVRN---LRVEAQTTS------SISLSWEVPDGTDPQNSTYCVQCTGDGGRTETRNTTDTRVTVDGLGPG----SLYTCSVWVEKD-GVNSS
  |..|   |||.. |..      |..|||. |        .|                    .||.|| ||    . |. .|... . .. ..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR-------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 PTPRH.AA FN3 297-376 22 3e-11 44.63 SMART 1-69 (69) Show / Hide 
Range on Protein: 297-376
Range on HMM: 1-69/69
Sequence Identity: 22% (21 aa)

PNPVRN---LTVEAQTNS------SIALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAHTNITVDRLEPG----CLYVFSVWVGK-NGINSS
| |..|   |.|.. |..      |. |.|. |           |.|.                ||. |.||      |.|.|..   |.  ..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----------IVGYR---------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 PTPRH.AA FN3 386-465 23 4e-13 50.86 SMART 1-69 (69) Show / Hide 
Range on Protein: 386-465
Range on HMM: 1-69/69
Sequence Identity: 23% (22 aa)

PNPVRN---LHMETQTNS------SIALCWEVPDGPYPQDYTYWVEYTGDGGGTETRNTTNTSVTAERLEPG----TLYTFSVWAEK-NGARGS
| |..|   |. .  |..      |. | |. |           |.|.               .| . |.||    | |.|.|.|.  |.|  .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----------IVGYR---------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 PTPRH.AA FN3 475-554 15 6.2e-09 36.93 SMART 1-69 (69) Show / Hide 
Range on Protein: 475-554
Range on HMM: 1-69/69
Sequence Identity: 15% (15 aa)

PNAVTS---LSKQDWTNS------TIALRWTAPQGPGQSSYSYWVSWVREGMTDPRTQSTSGTDITLKELEAG----SLYHLTVWAERN--EVRG
| ...    |.  |.|..      .. |.|..|           |...                 |.. |..|    . |. .|.|.      .|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----------IVGYR----------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 PTPRH.AA FN3 565-655 20 1.4e-12 49.02 SMART 1-69 (69) Show / Hide 
Range on Protein: 565-655
Range on HMM: 1-69/69
Sequence Identity: 20% (22 aa)

PNEVTD---LQNETQTKN------SVMLWWKAPGDPHSQLYVYWVQWASKGHPRRGQDPQANWVNQTSRTNETWYKVEALEPG----TLYNFTVWAER-N
|  ...   |. .  |..      || | ||.|        |...                             |.|. |.||    | |.|.|.|.  |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------------YTVTGLKPGQYPWTEYEFRVRAVNGN

DVASS
|. ..
DAGEG
Phosphatase PTPRH.AA Subfamily.N6.PD 815-1080 35 3.6e-75 244.3 In-house 9-294 (295) Show / Hide 
Range on Protein: 815-1080
Range on HMM: 9-294/295
Sequence Identity: 35% (99 aa)

DSNCGFADKYQQLSL--VGHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPI-HEEPGSDYINASFM------------PGLW-SPQEFIATQGPLPQ
|| .....|.   . .  |.. ..  ||..||||.|.||.| .|| ||   .. ||||||||...            .. .   ...|||||.|..|| |
sqtlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkd

TVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEVMENWTVRELLLLQV-EEQKTLSVRQFHYQAWPDHGVPSSPDTLL
|||.||...|. .||.|. .| |. || .|||  ..  ..|...|| . |. ....|.||... .  ..... ...|.|..||||||||..| ..| |..
tvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvl

AFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSF---VRKMRESRPLMVQTEAQYVFLHQCILRFL
 ...  .. .. || .||||||.|||||.| .|..|......||  .  .   ....|. |  .||||||||. ...  ..     
nfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyi
Phosphatase PTPRH.AA PTPc 819-1081 38 4.7e-131 442.6 SMART 1-308 (308) Show / Hide 
Range on Protein: 819-1081
Range on HMM: 1-308/308
Sequence Identity: 38% (121 aa)

GFADKYQQLSLVGHSQ---------SQMVASASENN--AKNRYR-NVLPYDWSRVPLKPIHEE----PGSDYINASFMPGLWSPQEFIATQGPLPQTVGD
||.. .. |  ..  .         |  .|   ||.   ||||. ....|| .|| |||...|    .|||||||....| |.| ..|.|||||| |. |
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRLVWEQQSHTLVMLTNCMEA--------GRVKCEHYWPLDSQPCTHGHLRVTLVGEEVME-NWTVRELLLLQVEE--------QKTLSVRQFHYQAWP
||| ||.|..|. |||.||||         ||.||..|||..  |.|.||..||.. ||... ..|.|.. .   ..        ..|..|...|| .||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

DHGVPSSPDTLLAFWRMLRQWLDQTME-----------------GGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQ
|||||.||| .|.| |. |.|  . ..                  ||..||||||.|||||..|.|....|..    . .|  |..||. || |||||.|
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQ

YVFLHQCILRFLQ
|.|...|||....
YIFCYRCILEYIK
Phosphatase PTPRH.AA Y_phosphatase 844-1078 47 5.1e-123 419.8 Pfam 1-243 (243) Show / Hide 
Range on Protein: 844-1078
Range on HMM: 1-243/243
Sequence Identity: 47% (116 aa)

NNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPG-LWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGR-VK-CEHYWPL--DSQ
|  ||||.....||..|| |.||.....||||||....|  |.|...|.||||.| |..|||| ||.|.... |||.|||| || .| |..|||.  ..|
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

PCTHGHLRVTLVGEEVMENWTVRELLLLQVEE--QKTLSVRQFHYQAWPDHGVPSS-PDTLLAFWRMLRQWLDQTMEG-GPPIVHCSAGVGRTGTLIALD
|.|.|...||.| ||.....|||.. .   ..  |.|..|...|| .|||||||.| |. .| | |..|.|  ... | .|..||||||.|||||..|.|
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAID

VLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILR
....|.. || .  | .|..||..|| |||||.||.|..|||| 
IMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase PTPRH.AA Subfamily.RB.PD 820-1081 47 5.69999999999e-112 364.7 In-house 2-261 (261) Show / Hide 
Range on Protein: 820-1081
Range on HMM: 2-261/261
Sequence Identity: 47% (125 aa)

FADKYQQLSLVGHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLT
|...|..|. ||..|... |....|.||||..|.||||.||| |. ...|...|||||...||  ||.|.||||||||.|| ||||.|||..|...||||
fseeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

NCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEVMENWTVRELLLLQveEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVH
...| |..|||.||| |..|...|...|||. |. ...|..||. . .  .... .|||.|...|||||||....|||.|.|..|........ .| .||
qlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvH

CSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFLQ
|||||||||| |||| ||...... ..  |..| ..||.| |.||||.||.|.|.|.|..|.
CsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldlle
Phosphatase PTPRH.AA Subfamily.R_Anemone_2.PD 820-1080 43 2.8e-92 300.4 In-house 2-261 (262) Show / Hide 
Range on Protein: 820-1080
Range on HMM: 2-261/262
Sequence Identity: 43% (113 aa)

FADKYQQLSLVGHS-QSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVML
.   |..|| . ..  .   |  . |.||||| |.|.|| .|| |.....|.|||||||....|  . ...||||.|||.|.||||.||||.| ..||||
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TNCMEAGRVKCEHYWPlDSQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWlDQTMEGGPPIV
...|.|..|...||| .... ..|.|.|.|  |  ......|.. . . ||...  |||||| .|||.|||.|. .||.. |  ... .|. . || .||
tqeeergkakvhryWP-skgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqveka-qqesgagpivv

HCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
|||||||||. ||.|.||.... |.|.  | .|...|| |.|||||.||.|... .| .|  
hcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal
Phosphatase PTPRH.AA Subfamily.N_Choan_1.PD 819-1080 39 4.6e-83 270.0 In-house 1-261 (262) Show / Hide 
Range on Protein: 819-1080
Range on HMM: 1-261/262
Sequence Identity: 39% (105 aa)

GFADKYQQLSLVGHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVML
||. .|..|. .| ...   . | ||  ||||.|.  || .|| ..| .|.  .|||||.|.||. ...|.||||||.|... .||..||||. ...||.
GfieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmv

TNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEVMENWTVRELLLlQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEgGPPIV
|. .|||..|| .||| ...  . |...|. . ||  ...  |.. | . |. .| .|.|..|.||||||||...  || | . ...  ..  .  | ..
treieagklkChryWPdenselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk-aplvi

HCSAGVGRTGTLIALDVLLRQLQSEG-LLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
||||||||||| |||| |.......   | . . |...|..| ||||| .|| |.....|. |
hCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal
Phosphatase PTPRH.AA Subfamily.R_Sponge_2.PD 834-1079 42 3.1e-82 267.4 In-house 15-260 (262) Show / Hide 
Range on Protein: 834-1079
Range on HMM: 15-260/262
Sequence Identity: 42% (105 aa)

QSQMVASASENNAKNRYRNVLPYDWSRVPLKPiHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYW
| . |  .|| .|||....|||| ||| |.. .....||||||||. |. ... .|||||||..||.||||.|||....|.|||||  | |. ||..|||
fslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYW

PLD-SQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEE-QKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQwlDQTMEG-GPPIVHCSAGVGRTGTL
    .  . |. .|||. || ......|.| | . .. .... |.|||. |||.|.||..  .||... ...  .|. .| .. .|.||.||||||| ||
PekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlr--aqkksgnkaitvvCsdgvgrtGtf

IALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRF
||..|..|. |. .  |......| .|. .||..|||||.|. .| .  
ialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalley
Phosphatase PTPRH.AA Subfamily.R_Anemone_1.PD 820-1080 39 1.5e-81 265.2 In-house 2-257 (258) Show / Hide 
Range on Protein: 820-1080
Range on HMM: 2-257/258
Sequence Identity: 39% (104 aa)

FADKYQQLSlVGHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLT
.|...|.|.  ...... ||. .||..|||| .....| ||| |.  .... |||||||.. .    ..|||||.||..||.||||.||.... ..||||
yaaefqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLt

NCMEAGRVKCEHYWPLdsQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWldQTMEGGPPIVH
| .|    ||..|||   .. ..|.|||.|  .||. ....|.|.| ...|...  |.|.|.  |||.|||.   ..|.. | ...   .. .  | .||
nliegekkkchqYwPd--stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks--slagarpvvvh

CSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
|||||||||. ...| .|.|...|  .  |  |...||.|| ||||. ||||.|. .|. |
CsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal
Phosphatase PTPRH.AA Subfamily.RA.PD 822-1080 42 2.4e-80 261.1 In-house 4-265 (266) Show / Hide 
Range on Protein: 822-1080
Range on HMM: 4-265/266
Sequence Identity: 42% (112 aa)

DKYQQLSLVGHSQS-QMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTN
.....|. |   ..   .|.  ||. |||. ..||||.||| |  .. |. ||||||||. |    ..|||.|||. .|| ||||..|||.|.|.||||.
eefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmlte

CMEAGRVKCEHYWPLDSqPCTHGHLRVTLVGEEVMENWTVRELLLLQV----EEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQwLDQTMEGGPP
  | .. ||  ||| .    |.|..||..  |.|.|..|||..|. |.    .|.|.  |||||...||. |||...  .| .. ... |.| . . | .
lkerkeekcaqywpdeG-lvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkk-lqqqsanhpi

IVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
||||||||||||.|.|| .| ....|..|  | .|...|  || ||||. ||.|... .| .. 
vvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlleyi
Phosphatase PTPRH.AA Subfamily.N12.PD 835-1080 42 5.2e-80 259.8 In-house 23-269 (270) Show / Hide 
Range on Protein: 835-1080
Range on HMM: 23-269/270
Sequence Identity: 42% (107 aa)

SQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWP
|. .....|| .||||...|||| ||| |. |.||.|||||||.|. |  ...|.||.|||||.|. ||||..||.. . .||. . .| |. |||.|||
steagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWp

LD-SQPCTHGHLRVTLVGEEVME-NWTVRELLLLQVEEQKtlSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDqtMEGGPPIVHCSAGVGRTGTLIA
    .....|...|||  |. .. ....| | . . .|..  .|.||||.||||||||||...||.. ...|.  .   || .||||||||||||.||.|
eegeeelefgefevtleeekavdddflirtLkveaqkesr--kvyqfhytaWPDhgvPssaksllelielvrelqe--sedaPlvvhCsaGvGrtGtiia

LDVLLRQLQSEGL---LGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
   ..|..| .   |  |. | ..|. |. .|||. ||........ ..  
idyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
Phosphatase PTPRH.AA Subfamily.RG.PD 820-1078 38 2.5e-77 251.3 In-house 2-261 (264) Show / Hide 
Range on Protein: 820-1078
Range on HMM: 2-261/264
Sequence Identity: 38% (100 aa)

FADKYQQLSLVGHSQS-QMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVML
......... . ...     ....||. |||. |..... |||.|.|. .. |.||||||.. |    .|.|.|||||..|. ||||..||......|||
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

TNCMEAGRVKCEHYWPLDSQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLS--VRQFHYQAWPDHGVPSSPDTLLAFWRmlRQWLDQTMEGGPP
|.  | || ... ||| . .| . ..|.|||. .|.... |||...| . . .| ..  |||.||  |||.|.|.|    | |.  ..   .. | || .
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvk--keeaankeeaGPi

IVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILR
||.||||||.||.|||| ||.||..|     . .....|  || .|.|| ||||... .|  
vvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydalle
Phosphatase PTPRH.AA Subfamily.N9.PD 824-1079 40 8.9e-74 239.8 In-house 6-273 (275) Show / Hide 
Range on Protein: 824-1079
Range on HMM: 6-273/275
Sequence Identity: 40% (106 aa)

YQQLSLVGHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCME
|...     .   ...    |  |||| .|| || .|| |. ..|.. ||||||.|. |   .. ||||||||..|| ||||.||||.  ..|| | ..|
yadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvve

AGRVKCEHYWPLDSQPC-THGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQT----------ME
 ||.|| .||||... .  .|.|.|. |. ||.|...|| | . .|..... .|  | . .|||.|||||  .|| . .. |...             ||
rgrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghl

GGPPI-VHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRF
|| ||||||.|||||.|.||. | .|...| .  .  |...|. |  ..||. ||.| ....| .   
sgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
Phosphatase PTPRH.AA Subfamily.RK.PD 820-1080 36 6.2e-73 236.6 In-house 2-266 (267) Show / Hide 
Range on Protein: 820-1080
Range on HMM: 2-266/267
Sequence Identity: 36% (98 aa)

FADKYQQL---SLVGHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEpGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLV
. . .. |   .  ..|..  .|   .|..|||. ..|.|| |.| |......  ||||||... .   |..||.|||||..|| ||||||..... ..|
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

MLTNC-MEAGRVKCEHYWPLDSQpCTHGHLRVTLVGEEVMENWTVRELLLLQ--VEEQKTLSVRQFHYQAWPDH-GVPSSPDTLLAFWRMLRQWLDQtME
|||.  .| ||||| .||| |..  ..|...|.||  |. ..  || . . .     ...  ||||.. .||.. .|| |  .||.. | . .. ..  |
mlteldvevgrvkClkyWPedte-vrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee-ee

GGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
 |. .|||.|| ||.|| ||.|..|  .. ||..  |  |...|.... ||.|| ||.|... || .|
eGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal
Phosphatase PTPRH.AA Subfamily.R_Ecdysozoa.PD 820-1078 37 1.8e-72 235.1 In-house 2-266 (269) Show / Hide 
Range on Protein: 820-1078
Range on HMM: 2-266/269
Sequence Identity: 37% (100 aa)

FADKYQQLSLV-GHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVML
..  |..|      |.|  |.   ||. ||||... ..|  || ||.|  .  ||||||||. |    ..||| |.|. .|.|||||...||.....|||
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml

TNCMEAGRVkCEHYWPLDsQPCTHGHLRVTLVGEEVMENWTVRELLLLQVE---EQKTLSVRQFHYQAWP-DHGVPSSPDTLLAFWRMLRQWLDQT--M-
.|  |  |  |..||| . . . .|.. |.|| || ..... ||| . ...   ....  | |..|..|. |  || .. .|| . ...|.   .   . 
snlteknrk-cakyWpie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsg

EGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILR
  .| .|||||||||.|...|||.|| ||. |  .  | .|.|.|. |.|.||  .|||||.. .. 
srsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad
Phosphatase PTPRH.AA Subfamily.N3.PD 836-1079 42 6.4e-72 233.3 In-house 18-259 (261) Show / Hide 
Range on Protein: 836-1079
Range on HMM: 18-259/261
Sequence Identity: 42% (103 aa)

QMVASASENNAKNRYRNVLPYDWSRVPLKpihEEPGsDYINASFM----PGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEH
.|  .|| ||||||..||||  || ||   |..  |||||...    |.    . .|||||||..|. |||..||||.|...||||. .|||||| .|||
isaarkpenlaknryrdilpydatrvklk---eset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChq

YWPLDSQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWldQTMEGGPPIVHCSAGVGRTGTLI
  .. ...|...|..  |.  ... .|||.| . |...  .. |. | ||||||||.... .| | . .|.   .. .  |.||||||.|||| ||.|..
yWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrkl--rsgkeePvvvhCsaGigrtGvli

ALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRF
 |  ....  . |   ||.||. |  .|||..|| |. ..||.     
lletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailka
Phosphatase PTPRH.AA Subfamily.N_Choan_2.PD 824-1080 33 1.7e-69 225.3 In-house 2-265 (266) Show / Hide 
Range on Protein: 824-1080
Range on HMM: 2-265/266
Sequence Identity: 33% (89 aa)

YQQLSLVGHSQSQMvASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLW-SPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCM
...|..   |....  ... |.. |||...||   .|| |....|.. . |||| ...|   .....||..|||| |. .|||..||......||.|. .
fkrldkqevseeai-PeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgle

EAGRVKCEHYWPLDSQP---CTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKtlSVRQFHYQAWPDHGVPSSPD------TLLAFWRMLRQWLDQTMEG
| || ||| ||| ...    ...|...|. . || .| . ...| | . .|..  ... |.|..|||||||...|       ||.  | .|.. ... ..
EkgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlekkgetr--rlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldka

GPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
.| .|||||||||||||||.|  .| |.... . . . ....|. |. .||.  || .|.. .. . 
ePllvHcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya
Phosphatase PTPRH.AA Subfamily.N13.PD 821-1080 39 5.8e-69 223.8 In-house 3-258 (259) Show / Hide 
Range on Protein: 821-1080
Range on HMM: 3-258/259
Sequence Identity: 39% (104 aa)

ADKYQQLSLVGHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKpihEEPGsdYINASFMPGLWSPQE--FIATQGPLPQTVGDFWRLVWEQQSHTLVML
|. ...|  .   ..  |.   ||..||||||||||| .||.|.   .| |  |||||..      .|  .||.|||||.|| |||..||||... ..|.
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklg---degg--yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamv

TNCMEAGRVKCEHYWPLDSQ-PC-THGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDqtmEGGPP
|.  | |.|||. |||   . .   .. |.|.|.. . .....||.| . ..| ...  | .... .|||||||||.. |.| . .|.  .   . || .
tlekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt---dagPi

IVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
||||||.||.|.||..||.|  .. .  .     |||.|| |  .|||. ||.| .. ||  | 
vvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl
Phosphatase PTPRH.AA Subfamily.N5_RR.PD 840-1080 34 1.8e-64 209.0 In-house 19-264 (265) Show / Hide 
Range on Protein: 840-1080
Range on HMM: 19-264/265
Sequence Identity: 34% (85 aa)

SASENNAKNRYRNVLPYDWSRVPLK-PIHEEPGSDYINASFMPGLWS-PQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDS
. . .. ||||...|| . ||| |.    |.. |.|||| .. |     . ..|||||||.|. ||||........ .||||.  || |||..|.| . .
evfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdae

QP---CTHGHLRVTLVGEEVMENWTVRELLLLQVEEqKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLD-QTMEGGPPIVHCSAGVGRTGTLIAL
     ..|.. .. ..    ....||.|.|...|.  . ||  . | .|||| .| ...||| . .  ..  . .... .| .||||||.||||  || .
dyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiai

DVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
. .|||. |. .  .. | ..|  |  ||||. || ..|. .  .| 
siavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl
Phosphatase PTPRH.AA Subfamily.RC.PD 822-1078 34 1.3e-63 206.4 In-house 4-285 (288) Show / Hide 
Range on Protein: 822-1078
Range on HMM: 4-285/288
Sequence Identity: 34% (97 aa)

DKYQQLSLVGHSQSQMVASASENNAKNRYRNVLPYDWSRVPL-------------------KPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGD
..|.|  |   ... .|   ||..|||| .|||||. ||.|                   . |. | ||.||||||. . . |. .||.|||| .||.||
aefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvdd

FWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWplDSQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRM
||...|.. . .||||.. |  | || .||  .    ..| . | |  ..   ....| | | .  ....  | |. | .|.....|  |  || . ...
fwrmiferkvkvivmltelkeGdrekcaeyw--eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqv

LRQWLDQT--------MEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILR
.| | |            .| .|||..|..|||. |||. ||  |..|  .  | .|.|.| .|||||..|.||..|.. .   
vkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlve
Phosphatase PTPRH.AA Subfamily.N1.PD 835-1077 37 4.8e-60 194.7 In-house 19-264 (268) Show / Hide 
Range on Protein: 835-1077
Range on HMM: 19-264/268
Sequence Identity: 37% (93 aa)

SQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEepgsDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWP
.. .|   || ..||||.| ||| ||. |.  .     ||||||..      ...| ||||||.|.. ||..||||.|....|| ...| ...|| .|||
etreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywp

LDSQP----CTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTL
 ...     . . .|.|.|. ||. ....|| | | ..|.|.|  . .|||  ||| |||.|| ..| |   .|. .  . . ||...|||||.||.|||
qeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtl

IALDVLLRQLQSEGLLGPFSF---VRKMRESRPLMVQTEAQYVFLHQCIL
  .| .| ... .| |        . ..|. |  ..||  |  |  . ||
slvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiail
Phosphatase PTPRH.AA Subfamily.N23.PD 857-1079 38 3.5e-57 185.4 In-house 115-348 (350) Show / Hide 
Range on Protein: 857-1079
Range on HMM: 115-348/350
Sequence Identity: 38% (91 aa)

DWSRVPLK-PIHEEPGSDYINASFMPGLW--SPqEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDS-QPCTHGHLRVTLVGE
| .||.|.     .  .|||||...  |   || .|||||||...|..||| .|||||| ..||||.  | .. ||..||| |  .. ..|.|||.|  .
dpnrvklqqstqpgqqddyinatylkeltpmsP-pfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslksl

EVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWL-----DQT-MEGGPP-IVHCSAGVGRTGTLIALDVLLRQLQ-SEG
.  |.|  | | | . . ..  .| ..|...|...|||.||..||||    .. .      .|  ||| | |.|||||||||||.  .   .|.|.  .|
rssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagng

LLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRF
..     ||..|. |  |||..... .| . .|..
iiniprvvrrlrqqRkymvqkkvilkklyeavlea
Phosphatase PTPRH.AA Subfamily.N14.PD 835-1081 35 2.7e-56 182.2 In-house 17-275 (275) Show / Hide 
Range on Protein: 835-1081
Range on HMM: 17-275/275
Sequence Identity: 35% (90 aa)

SQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEpGSDYINASFMPGLWSPQ--EFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHY
.|.  ||. |||...||||. .|| |.| .|.  ..||||| .    . .  ..|..||||..|| |||..||||. . .||||.  ||. |. .|.| .
llstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeksfky

WPLD---SQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRML---RQWLDQTMEG-----GPPIVHCS
    .  ..|. .||    |  .  . . | |  .  ..  .|  . |. |||||||. ....| | ...   |.  ....|.      | .||||||||
lPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCs

AGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFLQ
||| ||  |.|.  |. .  .   . ....|. | |.||| ||| |... ....|.    
aGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikylk
Phosphatase PTPRH.AA Subfamily.RN.PD 833-1076 38 3.5e-54 175.2 In-house 16-259 (264) Show / Hide 
Range on Protein: 833-1076
Range on HMM: 16-259/264
Sequence Identity: 38% (91 aa)

SQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWS-PQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEH
... ||.| .|  |||...||||| ||| ||   ..  |||||||..         .|||||||..|. |||..|||| .  .|.||.  ||  .|..||
pstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckr

YWPLDSQpCTHGHLRVTLVGEEV-MENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQtmEGGPPIVHCSAGVGRTGTL
| . .  ...   | || | .  ... || . | ... ..| .| |||. .||..|||.|. .|| | | . .| .||||.|.||||. |..|..| .|.
ywpdeGs-evyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG--rscpivvhcsdGaGrtGvy

IALDVLLRQLQS-EGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCI
     .   . . ..|. || .|.|..|. |  ...           
ilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltav
Phosphatase PTPRH.AA Subfamily.N_Nematode_1.PD 823-1080 30 2.1e-52 169.4 In-house 5-264 (265) Show / Hide 
Range on Protein: 823-1080
Range on HMM: 5-264/265
Sequence Identity: 30% (81 aa)

KYQQLSLVGHSQSQMVASASENNAKNRYRNVLPYDWSRVPLKpiHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCM
....|    . ... . ...... ||||..|   | .|| |.  .|   |||| | ..     |. || .|.|| .|. |||.|  ..  ..||| ...|
efralkkfndeekvkafkeaqeadknrykdvgcldknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckli

EAGRVKCEHYWPLDSQPCTHGH---LRVTL---VGEEVMENWTV-RELLLLQV--EEQKTLSVRQFHYQAWPDHGVPSSPDTLLafwrmlrQWLDQT-ME
 |..||..|.|. ... .. .    ..|.   .| . .|.     .   |.|    .||..|...... |||.|||.   . |       . |... .. 
ekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaal-------elleavrgs

GGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGP-FSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
|| .||||||.|||||..|.. .| .| ..  . .   .|.|.|||   .||.|||.|.|. .| ..  
kgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllnyf
Phosphatase PTPRH.AA Subfamily.N20.PD 842-1080 38 7.4e-51 164.6 In-house 24-256 (257) Show / Hide 
Range on Protein: 842-1080
Range on HMM: 24-256/257
Sequence Identity: 38% (92 aa)

SENNAKNRYRNVLPYDWSRVPLKPiheepGSDYINASFMPGLWSPQE--FIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLD-SQ
|  |||||..|||| .||||         ||||||..  .   .|  .|||||||  |. |||..| |..|  . |.|  .| | .||||||.   .|  
psnreknryrdilpydstrvplgk-----skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkk

PCTHGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQwldqTMEGGPPIVHCSAGVGRTGTLIALDVLLR
  |.|| |   .... . .| . ...     . ||.|...  ||||| |.| |... . |  |.    .   || .||||||.|||| ....||..  . 
plelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryark----shltgpmvvhcsagigrtgvflcvdvvfc

QLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
 .  .  .  | .||| |  ||||. || | .. .|  |   
aivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl
Phosphatase PTPRH.AA Subfamily.N_Nematode_4.PD 832-1078 31 5.7e-48 154.9 In-house 13-261 (264) Show / Hide 
Range on Protein: 832-1078
Range on HMM: 13-261/264
Sequence Identity: 31% (79 aa)

HSQSQMVASASENN-AKNRYRNVLPYDWSRVPLKpiHEEPGSDYINASFMPGLwSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCE
. .....|||||.|  ||||...|  | .|| ||  . .|  ||| ||.|       ..|.|||||..|. ||| .|.......||| . .| |  ||. 
kappnvtasaseknsdknryadilcidetrvvlk--nrdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekca

HYWPLDSQP-CTHGHLRVTLVGEEVM--ENWTVRELLLLQVE---E--QKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQwldqTMEGGPPIVHCSA
|.| .|.   ..|. |.||| ....   .  .. | . ..|   .   . | |. .... |.|.  |  . ... .......      . .|..||||||
ryypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk----kkkekPivvhcsa

GVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILR
|||| ||. .|    ...  . .     ||..|. |   ||.. |..||  ...  
GvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvlie
Phosphatase PTPRH.AA Subfamily.N_Nematode_6.PD 836-1080 29 6.1e-43 138.5 In-house 16-252 (253) Show / Hide 
Range on Protein: 836-1080
Range on HMM: 16-252/253
Sequence Identity: 29% (72 aa)

QMVASASENNAKNRYRNVLPYDWSRVPLKpihEEPgSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPL
... .  ... .|||.|.  .| .|. |.   ...   || |...     |. .| ||.|| .|. .||...  . .. .||| . .| |. |. .| . 
seataflkfkdrnrytniqCcdagrlkla---dde-dfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsd

DS-QPCTH-GHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQwldQTmegGPPIVHCSAGVGRTGTLIAL
   .      .  |. .|.. ..  .|| |. .  . ..   |. .|...||||||| | .. |.  ....   ..    | .|||||||||||||. . 
kvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkk---dk---kPivvhCsaGvGrtGtlali

DVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
..|. |..    |  . . |.|| |   |||| ||.. ..|.| .| 
liilealrlpdfqgvkdllvklreerfravqtevqylyalrcvleyl
Phosphatase PTPRH.AA Subfamily.R_Nematode_2.PD 841-1078 31 2.5e-42 136.3 In-house 26-258 (261) Show / Hide 
Range on Protein: 841-1078
Range on HMM: 26-258/261
Sequence Identity: 31% (74 aa)

ASENNAKNRYRNVLPYDWSRVPLkpIHEEPGSDyINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLD-SQP
|. .. |.|| .|   . ..|    | ..  .. | | ..|    |. |||||||| .|. ||| .|  ..  ..|||....|  . |||.|.||. || 
aylpkdkhRypdvPCkpetavev--ivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqk

CTHGHLRVTLVGEEVMENWTVRELLLLQVEEQK---TLSVRQFHYQAWPDHGVPSSPDTLLafwrmlrQWLDQTMEG-GPPIVHCSAGVGRTGTLIALDV
 . |..... |..| . .  . .  |  .....   | .|. . |. |||.||| | . |. |. . .   | .||||||.|||...|. ..| |... .
ldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelf-------eLlelvkksekPivvhCsaGiGRtmafigtey

LLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILR
  .     ....|| |.  .||| |. .|.   |         
lareveadptieltealkelrehRwkgiqtesqlywltlgaly
Phosphatase PTPRH.AA PTPc_motif 975-1078 43 8.3e-42 146.13 SMART 1-92 (92) Show / Hide 
Range on Protein: 975-1078
Range on HMM: 1-92/92
Sequence Identity: 43% (47 aa)

SVRQFHYQAWPDH-----GVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQY
.|...|| .||||     |||.  | .| | |..|.         |..||||||.|||||..|.|....|      .  | .|..||..|| |||||.||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQY

VFLHQCILR
.|...||| 
IFCYRCILE
Phosphatase PTPRH.AA Subfamily.N_Nematode_5.PD 842-1080 24 1.1e-33 107.9 In-house 23-257 (258) Show / Hide 
Range on Protein: 842-1080
Range on HMM: 23-257/258
Sequence Identity: 24% (58 aa)

SENNAKNRYRNVLPYDWSRVplkpIHEE-PgSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPC
.|  |||. .|  .| .||    . .. . ..||||| .    . ...| || |||.|. ||||.| ... ...|.|..|. . ... .     .  ..|
eknlkknrskdvkilDetrV----kltded-dsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketavsffpletgdyl

THGHLRVTLVGEEVMENW-TVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAfwRMLRQWLDQTMEG-GPPIVHCSAGVGRTGTLIALDVLLR
.. ..    ||.|.  .   . .|  .    . ..  |.. |... ||..   ...  |... |...     | .|....|.||.||...|.|   ||..
nlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsdlGlgRagtflllsvaie

QLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
.  .     ..|.|. || .|.. .||.......| ..    
qlnngkepnideilkkirsqRpgavesliqyasvyaavldyi
Phosphatase PTPRH.AA Subfamily.R_Nematode_3.PD 837-1080 24 1.8e-33 107.4 In-house 16-266 (267) Show / Hide 
Range on Protein: 837-1080
Range on HMM: 16-266/267
Sequence Identity: 24% (63 aa)

MVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPgLWSPQEFIATQGPL--------PQTVGDFWRLVWEQQSHTLVMLTNCME---AG
.  | |.. ...|. .|. .  .|| ||       .|.|.|...  . .  ..| ||.|.         .|.  || .. ..... .||| . .|    .
natslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgee

RVKCEHYWPLDSQ-PCTHGHLRV--TLVGEEVMENWTVRELLLlQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWldqtmEgGPPIVHCSA
  || .|.|.. .  .. . . |  | . .|. |.   |.| . ..|..|.  |.  .|..|.....| .|...|.  .....      .  | .||||.
eekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveks-----k-tpvvVHCsd

GVGRTGTLIALDVLLRQ-LQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
|..|..|| | ..     ..|.| |   | . ..|..|.  .|||.. |.  .||..| 
GisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkll
Phosphatase PTPRH.AA Subfamily.N_Nematode_egg.PD 833-1080 27 2.1e-27 87.5 In-house 15-256 (257) Show / Hide 
Range on Protein: 833-1080
Range on HMM: 15-256/257
Sequence Identity: 27% (67 aa)

SQSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAgrVKCEHY
.|   | ....  | | . |   . ||| |.  .     |.| | .. |    .||| .| || .|| ||||.|..... .||||  .|.   .||.|||
eislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyy

WPL-DSQPCTH--GHLRVTLVGEEVME--NWTVRELLLLQVEeqktlsVRQFHYQAWPdHGVPSSPDTLlAFWRMLRQWLDQtmeGGPPIVHCSAGVGRT
  .|..     | ||.. .. .      ..| .| |.  .        . . . ||  . |      |.||.  .      | .|..  || ...||.|.
wpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgd------deelflehwq-gdvnylsdvy-splrvlrklrnl---skpvvvqdilGvska

GTLIALDVLLRQLQSEGLLG-P-FSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
.. | .|    .   .    |  .|  |.| |...|.|... .|.|.        
atlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlffi
Phosphatase PTPRH.AA Subfamily.N_Fungi_PTP1.PD 832-937 34 4.9e-25 79.6 In-house 29-152 (343) Show / Hide 
Range on Protein: 832-937
Range on HMM: 29-152/343
Sequence Identity: 34% (43 aa)

H----SQSQMVASASENNAKNRYRNVLPYDWSRVPLK--------PIHEEPGSDYINASFMP----GLWSPQEF--IATQGPLPQTVGDFWRLVWEQQSH
.    |.  ...|  |  |||||.|.|||. ||| ||          |   ..|||||...     .     .|  ||||.|||.|| ||.... . . .
dsdsesddviissGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvk

TLVMLTNCMEAGRVKCEHYWPLDS
 ...||. .| .. ||..||.  |
vilsltsdvelnlekcyrYWqegs
Phosphatase PTPRH.AA Subfamily.N_Nematode_eak.PD 834-1080 23 2.6e-19 61.0 In-house 16-280 (281) Show / Hide 
Range on Protein: 834-1080
Range on HMM: 16-280/281
Sequence Identity: 23% (62 aa)

QSQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPgSDYINASFMPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYW
.|. |..  |.  .||  ...|.|   | | .   ..   ||||| .      ...| |  .  . |  ||..| ||.|..|.| . .| .  | . |.|
lsirvtarleavnrnrvvkivpqdrylvrltssqlnr-dGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyf

PLDSQPCTHGHLRVTLVGEEVMENWTVRELLLLQVEeQKTLSVRQFHYQAWPDHGVPSSPDtLLAFWRMLRQ------------WLDQTM-------EGG
 ...   .|.| |.     | .|     || |..  ..|  |  ...  | .  .|| .||. .....             |  |.           ||.
pdktevlkyGildverkeyavkrniletrllilrkG-nethrvlhykvfGwtettlpkyed-flalrkvmkevGvlllivmksallrstlkkyihtppsf

PPIVHCSAGVGRTGTLIALDVLLRQLQS--EGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCILRFL
 .. |  |.|... .|.|.| ...  . |     ..|... |   | .. |. |... .| .|     
apiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl
Phosphatase PTPRH.AA Subfamily.N_Fungi_PTP1.PD 973-1079 27 3e-14 44.1 In-house 212-341 (343) Show / Hide 
Range on Protein: 973-1079
Range on HMM: 212-341/343
Sequence Identity: 27% (35 aa)

TLSVRQFHYQAWPDHGVPSSPDTLLAFWR--------MLRQWLDQTMEGGPPIVHCSAGVGRTGTLIALDVLLR------QLQSE--------GLLGP-F
| |.... |.| ..   |  .|            .  .   .. .. | .|||||||||||||..|| ||       .|. |         .  . .  |
pyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlis

SFVRKMRESRPLMVQTEAQYVFLHQCILRF
 ..|. |  |||.  |..|.....| .   
iivnelrkqrismvqnldqfifiYeallfy
Phosphatase PTPRH.AA Family.DSP.PD 971-1089 20 3.6e-10 31.1 In-house 147-256 (387) Show / Hide 
Range on Protein: 971-1089
Range on HMM: 147-256/387
Sequence Identity: 20% (25 aa)

QKTLSVRQFHYqAWPDHGVPSSPDTllaFWRMLRqWLDQTM-EGGPPIVHCSAGVGRTGTLIALDVLLR-QLQSEgllGPFSFVRKMResrPLMVQTEAQ
.|.|...  .. ...||..|.       | . .. ....   ..|   ||| ||.||.||||.   . . .|  |     . .||. |   | ... . .
tkelgikylri-pidDhnapplenl---fekaid-fieegndskgvVlVHCkaGkgRsgtliiaYlmksegltle---ealdwvrskR---pgvitpnqg

YVFLHQCILRFLQQSAQAPAE
..  ... .  . .  . . |
flkqlkdlekeklkvssevme
Phosphatase PTPRH.AA Subfamily.PTPDC1.PD 979-1074 29 3.9e-10 30.9 In-house 137-222 (229) Show / Hide 
Range on Protein: 979-1074
Range on HMM: 137-222/229
Sequence Identity: 29% (28 aa)

FHYQAWPDHGVPSsPDTLLAFWRMLrqwlDQTMEGGPPIVHCSAGVGRTGTLIALDVLLRQLqseglLGPFSFVRKMRESRPLMVQTEAQYVFLHQ
|.  ...|.||.|  ...|   ...    |...| |   ||| || |||| |||  ..  .      |..   ....|. ||  .|||  ....  
fynfglkDygvas-leriLdivkvv----dfaleegkiavHCHAGlGRtGvliacylvyakr-----ltaeeaiklvrskrpksiqtreqvelvee
Phosphatase PTPRH.AA Subfamily.PTEN.PD 985-1033 34 5.8e-06 17.2 In-house 68-114 (305) Show / Hide 
Range on Protein: 985-1033
Range on HMM: 68-114/305
Sequence Identity: 34% (16 aa)

PDHGvPSSPDTLLAFWRMLRQWLDQTMEGgPPIVHCSAGVGRTGTLIAL
||  | . . |  . . . .||..  .    .||| || ||||..|.  
dDhn-pptleLleeivedvdkwLkedksn-VvavHCkaGkGRtGvmica
Phosphatase PTPRH.AA Subfamily.TPIP.PD 986-1032 36 6e-06 17.4 In-house 12-56 (245) Show / Hide 
Range on Protein: 986-1032
Range on HMM: 12-56/245
Sequence Identity: 36% (17 aa)

DHGVPSSpDTLLAFWRMLRQWLDQTMEGGpPIVHCSAGVGRTGTLIA
|| ||   . |. | . ...||.. .|    ..||  | |||||.. 
dhnvPtl-eelvvftkevkewlakdlenv-vaihckGGkgrtGtivc
Phosphatase PTPRH.AA Subfamily.CDC14.PD 1013-1037 56 6.8e-06 17.3 In-house 198-222 (258) Show / Hide 
Range on Protein: 1013-1037
Range on HMM: 198-222/258
Sequence Identity: 56% (13 aa)

GGPPIVHCSAGVGRTGTLIALDVLL
|  .||| ||.|||||||.  ..  
eGaiavhCkaGLGrtgtligcylik
Sequence
Name Sequence Type Origin Length Description Download
PTPRH.AA Protein None 1115 None Fasta, JSON
PTPRH.NA RNA None 3345 None Fasta, JSON
PTPRH.AA.PD_819-1081 Protein Phosphatase Domain None 263 None Fasta, JSON