Gene PTPRO
PTPRO
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTPRO.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Fn3 | PTPRO.AA | FN3 | 723-802 | 18 | 8e-07 | 29.92 | SMART | 1-69 (69) | Show / Hide |
Range on Protein: 723-802 Range on HMM: 1-69/69 Sequence Identity: 18% (18 aa) PAPPKS---LFAVNKTQT------SVTLLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTISSLLPA----TAYNCSVTSFSH--DSPS | ||. | ... | | |||| | . .| .. .|.. | | | |. .|. ... . .. PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR--------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG |
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Phosphatase | PTPRO.AA | PTPc | 937-1197 | 40 | 7.50000000001e-128 | 431.96 | SMART | 1-308 (308) | Show / Hide |
Range on Protein: 937-1197 Range on HMM: 1-308/308 Sequence Identity: 40% (128 aa) KFSLQFEELKLIGLDI---------PHFAADLPLNR--CKNRYT-NILPYDFSRVRLVSMNEE----EGADYINANYIPGYNSPQEYIATQGPLPETRND .|. .||.|. . .. . |..| || .||||. .|..|| .||.| . ..| || ||||||||.||..| .||.||||||.| .| GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED FWKMVLQQKSQIIVMLTQCNEK--------RRVKCDHYWPFTEEPIAYGDITVEMISEEEQD-DWACRHFRINYAD----------EMQDVMHFNYTAWP ||.|| |||..|||||..|.|| |.||..||| . | ||.|||...||| . |. |.|.. . . | . |.|..||.|| FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP DHGVPTANAAESILQFVHMVRQQATKS-------------------KGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTE ||||| . ..|.|.|...||.. | ||...|||||.||||||.|.| ..|.|.. |||...|..||..|. ||||| DHGVP--ESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTE EQYIFIHQCVQLMWM |||||...|.. . EQYIFCYRCILEYIK |
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Phosphatase | PTPRO.AA | Y_phosphatase | 962-1194 | 46 | 1.8e-122 | 417.97 | Pfam | 1-243 (243) | Show / Hide |
Range on Protein: 962-1194 Range on HMM: 1-243/243 Sequence Identity: 46% (114 aa) NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPG-YNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRR-VK-CDHYWP--FTEE |. ||||..|..||..||.| .....|. ||||||||.| |..|..||.||||.|.| .|||.||.|||...||||..| |. | .| |..||| .. NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ PIAYGDITVEMISEEEQDDWACRHFRINYAD----EMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQAT-KSKG--PMIIHCSAGVGRTGTFIAL |. |||..|...|||. .|. |.|.. . | . |.|. ||.||||||| .. |.|.|...||.. . | |...|||||.||||||.|. PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPES-QPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAI DRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQL | ..|...... |||...|..||. |. ||||||||||..||.. DIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE |
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Phosphatase | PTPRO.AA | Subfamily.RB.PD | 937-1195 | 55 | 4.5e-121 | 394.6 | In-house | 1-259 (261) | Show / Hide |
Range on Protein: 937-1195 Range on HMM: 1-259/261 Sequence Identity: 55% (146 aa) KFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML .|| ..|||| .| | .. ||... ||.|||.||||||| |||.| ....|...||||||||||||||.||||||||||||..|||.||...||.||||| rfseeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivml TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPtaNAAESILQFVHMVRQQATKS--KGPMII ||. || ..||..||| .|||..||||.|....|.|.|.|..|.|.|. .|...|.....|.||||||| ......|.||..||....|. |.|... tqlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgkekrkvrqyhftsWpdhgvP--ektktlldfvrtvreaiekkaskkPivv HCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLM ||||||||||||||||||||.|.....||..|.|.|.|. |...||||.||||||.|.. . HCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl |
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Phosphatase | PTPRO.AA | Subfamily.R_Anemone_2.PD | 953-1193 | 46 | 1.7e-91 | 297.8 | In-house | 18-258 (262) | Show / Hide |
Range on Protein: 953-1193 Range on HMM: 18-258/262 Sequence Identity: 46% (112 aa) PHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWP .| | |. ||||.|||.|| .||.| ...|||.||||||||.||.. ..|||||.||||| .|||.|| .|.|..||||||..|. ..|...||| . tlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWP fTEEPIAYGDITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPTANaaESILQFVHMVRQQA-TKSKGPMIIHCSAGVGRTGTFIAL ....||...||. .| | .|. |.|... .| ..| |.||.|||.|||. |.|..| |.. ....||...||||||||||.|||.| | -skgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesg--aslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiav DRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQ |..|.. . ||... |...|. | ||||..||.||.. .. dillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvll |
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Phosphatase | PTPRO.AA | Subfamily.N_Choan_1.PD | 939-1193 | 44 | 7.1e-88 | 285.8 | In-house | 3-258 (262) | Show / Hide |
Range on Protein: 939-1193 Range on HMM: 3-258/262 Sequence Identity: 44% (112 aa) SLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQ ..|.|. ||.| . |. . |. ||||.|| || .||.. .|.. .||||||..|||....||||||||.|.. ..||.||..|| ..|||.|. ieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtr CNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRI-NYADEMQDVMHFNYTAWPDHGVPTAnaAESILQFVHMVR-QQATKSKGPMIIHC |. ..|| .||| .. . .||.||...||||. ...|.|.. . | ..| ...||||||||||... .|.| . |. .. .|.| |..|||||||| eieagklkChryWPdenselklgdvtvkslseeekktyierkfkleresgetreveqlaytaWPdhGvPat--tkellefrkavlkatkkktkaplvihC SAGVGRTGTFIALDRLLQHIRDH-EFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQ ||||.||||||....... | .|. .|.|.| |. |||| || |....|. saGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavl |
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Phosphatase | PTPRO.AA | Subfamily.R_Sponge_2.PD | 956-1192 | 41 | 7.7e-82 | 266.1 | In-house | 19-257 (262) | Show / Hide |
Range on Protein: 956-1192 Range on HMM: 19-257/262 Sequence Identity: 41% (99 aa) AADLPLNRCKNRYTNILPYDFSRVRLVSmNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFT- .| |. | |||...|||||.||||| . ......|||||... ||.... ||||||||.|| .|||.||. .|...|||||..|. . || .||| . . iaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPekv EEPIAYGDITVEMISEEEQDDWACRHFRINYA---DEMQDVMHFNYTAWPDHGVPTAnaAESILQFVHMVRQQATKSKG-PMIIHCSAGVGRTGTFIALD | ||...| . .||. |.. |..... . .. .|| .|...|||.|.||. | |.|....|... .||.. .....||.|||||||||||| . deeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkd--atsllelikrvlraqkksgnkaitvvCsdgvgrtGtfiald RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV |.... | .|. .. ..|. |. .||...|| |||. . svlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdal |
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Phosphatase | PTPRO.AA | Subfamily.R_Anemone_1.PD | 942-1193 | 38 | 5.4e-81 | 263.4 | In-house | 6-254 (258) | Show / Hide |
Range on Protein: 942-1193 Range on HMM: 6-254/258 Sequence Identity: 38% (97 aa) FEELKlIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNE |..|| . . . .| . |. ||||..|...| ||| | .....| .||||| |. ... ...||||.||.|| .|||.||.|.|...|||||. .| fqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnlie KRRVKCDHYWPFteEPIAYGDITVEMISEEEQDDWACRHFRINYADEM--QDVMHFNYTAWPDHGVPTAnaAESILQFVHMVRQQATKSKGPMIIHCSAG .. || .||| .. .||...|.. ..|.. |. .|.. .. ..| . |.....| |||.|||. | ..|.... |... .. . |...||||| gekkkchqYwPd--stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqy--atavLglrrkvqksslagarpvvvhCsaG VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQ |||||.|...| .|.... .. ||| | .|. | ||||.|||.|||. |. vgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavl |
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Phosphatase | PTPRO.AA | Subfamily.RG.PD | 938-1193 | 39 | 5.6e-81 | 263.2 | In-house | 2-260 (264) | Show / Hide |
Range on Protein: 938-1193 Range on HMM: 2-260/264 Sequence Identity: 39% (103 aa) FSLQFEELKL-IGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML .. ||||.. ||. .. . |. |||..||.... |||.| .. ...| |||||.|| ||. .|||.|||||.|| .|||.|. ....|||||| leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml TQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYA--DEMQD--VMHFNYTAWPDHGVPTANAAEsiLQFVHMVRQQATKSKGPM |. .|| | ..| ||| .||. .....| ..|.|.... |.| .. |. .. | ...|| |||.|.|. .. . |||. . ... ||.. tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfv--lifvkkeeaankeeaGPi IIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQ .|.||||||.||.|||| |||.....| |...... .|. | .|.|||||.||.. .. vvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydall |
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Phosphatase | PTPRO.AA | Subfamily.N12.PD | 957-1194 | 42 | 1.4e-80 | 261.7 | In-house | 27-267 (270) | Show / Hide |
Range on Protein: 957-1194 Range on HMM: 27-267/270 Sequence Identity: 42% (104 aa) ADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFT-E .. . |. |||| .|||||.||| | ..|||| ||||||.| | ....||||.|||||.| .|||.|. ... .|.||. . | . ||..||| . | gekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpeege EPIAYGDITVEMISEEEQD-DWACRHFRINYADEMQDVMHFNYTAWPDHGVPTAnaAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQ |.. .|...|....|. | |. | .... .| . | |.||||||||||.. |.|.|.....||. .... |...||||||||||| ||.| . eelefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPss--aksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvre HIRD---HEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQL ... | .|. || |.| | ..|||.||| .....|. llkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae |
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Phosphatase | PTPRO.AA | Subfamily.N5_RR.PD | 957-1194 | 40 | 2.7e-77 | 251.1 | In-house | 18-262 (265) | Show / Hide |
Range on Protein: 957-1194 Range on HMM: 18-262/265 Sequence Identity: 40% (99 aa) ADLPLNRCKNRYTNILPYDFSRVRLVSMN-EEEGADYINANYIPGYNSP-QEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFT ... . ||||..||| . ||| | | . |.| ..||||||| ||. . |.|||||||.| .|||.|. |...|.|||||. .|..| || .|.| .| levfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPda EEP---IAYGDITVEMISEEEQDDWACRHFRINYADE-MQDVMHFNYTAWPDHGVPTAnaAESILQFVH---MVRQQATKSKGPMIIHCSAGVGRTGTFI . |||. ... . |..|. |.. ..|. . ...|.|. ||.|||| .| ....|..|. |..... .|...|||||.|||| ||| edyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPdd--intlldlvleveesreeenaklaPvvvhcsaGiGrtGcfi ALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQL . ....|....||.|..|...| | ||||.||| .||. . | aisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl |
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Phosphatase | PTPRO.AA | Subfamily.RK.PD | 957-1192 | 39 | 5.5e-77 | 249.9 | In-house | 24-262 (267) | Show / Hide |
Range on Protein: 957-1192 Range on HMM: 24-262/267 Sequence Identity: 39% (95 aa) ADLPLNRCKNRYTNILPYDFSRVRLVSMNEEeGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQC-NEKRRVKCDHYWPfTE | .. || |||...||.|| |.|.|.|.... .|||||..| .|. |...|.|||||.|| .|||..|..... |||||. |. ||||.||| . akkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyWP-ed EPIAYGDITVEMISEEEQDDWACRHFRINY----ADEMQDVMHFNYTAWPDH-GVPTAnaAESILQFVHMVRQQATK-SKGPMIIHCSAGVGRTGTFIAL . |||| ||... | . | | ||.. .|.. | .|....||.. .||. ..|.|.... | .. . ..|....||.|| ||.|||||.| tevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvs--krsllklirrvkksqeeeeeGrivvhClaGaGrsGtfiai DRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV .|. |. .. ||. | ..|.... ||.|||||.|... . divlemieregvvdvfnavktlrnrkvnmveteeqykfvydvi |
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Phosphatase | PTPRO.AA | Subfamily.RA.PD | 956-1193 | 41 | 1.4e-76 | 248.8 | In-house | 21-262 (266) | Show / Hide |
Range on Protein: 956-1193 Range on HMM: 21-262/266 Sequence Identity: 41% (102 aa) AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPfTE .|... |. |||. .||||||||| | .. || .||||| .| ||. ...||.|||. || .|||.|. .|||. |||||. .|... ||||| .| tankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqywp-de EPIAYGDITVEMISEEEQDDWACRHFRINY-AD-----EMQDVMHFNYTAWPDHGVPTAnaAESILQFVHMVRQQATKSKG-PMIIHCSAGVGRTGTFIA ..||.|.||. |.. |.. |.| .. .| . . | | .|.||. |||. . .|.... |... .| . |...|||||||||||||.|| GlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpae--gkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtfiv LDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQ .|. .. . .|. . |...| | ||||.||| ||.. .. ldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvll |
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Phosphatase | PTPRO.AA | Subfamily.N9.PD | 956-1192 | 42 | 2.1e-76 | 248.4 | In-house | 20-270 (275) | Show / Hide |
Range on Protein: 956-1192 Range on HMM: 20-270/275 Sequence Identity: 42% (101 aa) AADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTE |. |..| |||||..| || .|| | ...|.| .||||||.. ||. .. .|||||||..| .|||.|| .|. .||| |.. |..|.||.||| .| asklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywplee -EPIAYGDITVEMISEEEQDDWACRHFRIN--YADEMQDVMHFNYTAWPDHGVPTanAAESILQFVHMVRQQA-TK------------SKGPMIIHCSAG . . .||..|. .. |...|. |.. |. .|.. |.|| ...|||.||| .|.|.|.....||.. .|. |...|||||.|||||||.|| | essaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPs--saaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaG VGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV ..... . ||. |. .|. | ..||.||| | ...| iGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylav |
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Phosphatase | PTPRO.AA | Subfamily.N3.PD | 949-1193 | 41 | 2.5e-75 | 244.5 | In-house | 13-257 (261) | Show / Hide |
Range on Protein: 949-1193 Range on HMM: 13-257/261 Sequence Identity: 41% (103 aa) GLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEeegaDYINANYI----PGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRR .. || .| | |||| .||||| ||.|.. . |||||||. |. . . ||||||||..| .|||.|| .|||..|||||. |. ||| kpglaisaarkpenlaknryrdilpydatrvklkeset----dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGr VKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYAD--EMQDVMHFNYTAWPDHGVPTANaaESILQFVHMVRQQATKSKGPMIIHCSAGVGR | .||| ||. . .|...|.. .|.|. . |.. .. .. | . .... |.||||||||. . ...|.||. ||. ... |...|||||.|||| vkChqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPdds--adflefvervrklrsgkeePvvvhCsaGigr TGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQ .|.|. |. | .| | .| .|..|| |...|||..|| |. ... tGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeail |
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Phosphatase | PTPRO.AA | Subfamily.N_Choan_2.PD | 962-1193 | 38 | 3.6e-75 | 243.9 | In-house | 21-262 (266) | Show / Hide |
Range on Protein: 962-1193 Range on HMM: 21-262/266 Sequence Identity: 38% (93 aa) NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYN-SPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTE-EPIA |. |||..||| .|||| ...|.. . ||||||..|.. ....|||..|||| | ..||.|....|.. |||.|. .|| |||. ||| | ... nkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk Y--GDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANA----AESILQFVHMVRQQAT--KSKGPMIIHCSAGVGRTGTFIALDR |.|.| .||| .. . .. |... .|.....|| |..|||||||... ....|. .. ||.. . ..|...|||||||||||.||.| .. ladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDi LLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQ . .. ||.| ...|.| .|| .||. ||| .... |. avrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavv |
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Phosphatase | PTPRO.AA | Subfamily.N6.PD | 960-1194 | 41 | 3.2e-73 | 238.0 | In-house | 38-292 (295) | Show / Hide |
Range on Protein: 960-1194 Range on HMM: 38-292/295 Sequence Identity: 41% (104 aa) PLNRCKNRYTNILPYDFSRVRLVSM-NEEEGADYINANYI--------PGYN--SP---QEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRV . |. |||| ||||.| .|| | .. |.|||||||| | | | ..||||||.|..| .|||.|| |..|..|||.|. .|. . ienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqensrvivmttkevergkn KCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINY---ADEMQDVMHFNYTAWPDHGVPTAnaAESILQFVHMVRQQA--TKSKGPMIIHCSAGV || .||| .|. ..|.|||..|||....|. |.| .. .|.. .......||||||||. .. .|.|.. |.......||...|||||.||| kCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkd--pgvvlnfledvnkkqeelekagpivvhcsaGi GRTGTFIALDRLLQHIRDHEF---VDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQL |||| .| .|. |. . . .|| . ..||.| .||||.||.|. ..|| GrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqf |
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Phosphatase | PTPRO.AA | Subfamily.R_Ecdysozoa.PD | 942-1192 | 36 | 6.1e-73 | 236.7 | In-house | 6-264 (269) | Show / Hide |
Range on Protein: 942-1192 Range on HMM: 6-264/269 Sequence Identity: 36% (95 aa) FEELK-LIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCN .|.|. . . ... | .|||| .| ..| ||.| .| .| .|||||..| ||. ...|| |.|. .| .|||.|. .|....||||.. . yekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlt EKRRVkCDHYWPFTeEPIAYGDITVEMISEEEQDDWACRHFRINYAD-----EMQDVMHFNYTAWP-DHGVPtaNAAESILQFVHMVRQQAT-----KSK || | |..||| . . |||| |...|||...|.. |.. . . . . |. ..||.|.| || ..|...|.....||. |.. eknrk-cakyWpie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvP--evargllklieqvrelyklnklsgsr GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV |...||||||||.|.|.||| |||... . |||. | ..|| | .|| |||.|... . sPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyral |
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Phosphatase | PTPRO.AA | Subfamily.N13.PD | 962-1192 | 40 | 3.4e-70 | 227.9 | In-house | 26-254 (259) | Show / Hide |
Range on Protein: 962-1192 Range on HMM: 26-254/259 Sequence Identity: 40% (96 aa) NRCKNRYTNILPYDFSRVRLvsmnEEEGAdYINANYIP--GYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFT-EEPI |. |||| |.|||| .||.| ..||. ||||..| . ||||.||||||| .|||.|| .||...|.|.|. || .|||. ||| . .... nkdknryrnvlPydetrvkl----gdegg-yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerknkkl A-YGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMHFNYTAWPDHGVPTAnaAESILQFVHMVRQQATkSKGPMIIHCSAGVGRTGTFIALDRLLQH .. ..||.. ...|... |.. .. . | ..|.|.|...|||||||.. |....||| ||. .| ..||...|||||.||.|..|..| .|. kvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPss--aaelvqfvaevrllqt-dagPivvhcsaGiGrsGvlitidvvlgl IRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV | .. .|. .| ..| | ..|||..||||... . ierdkefdvkeivrklreqrqgvvqtkdqyifvykai |
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Phosphatase | PTPRO.AA | Subfamily.RC.PD | 956-1192 | 33 | 5.7e-66 | 214.1 | In-house | 20-283 (288) | Show / Hide |
Range on Protein: 956-1192 Range on HMM: 20-283/288 Sequence Identity: 33% (90 aa) AADLPLNRCKNRYTNILPYDFSRVRL-------------------VSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVML | . |. ||||...||||. || | .. |||..|||| .| .| |. |||.|||| || .|||.|. ..| ..||||| iarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivml TQCNEKRRVKCDHYWpfTEEPIAYGDITVEMISEEEQDDWACRHFRINYADE--MQDVMHFNYTAWPDHGVPTANaaESILQFVHMVRQQ---A------ ...| | || .|| | ||||. |.. .. |. | . . . ..|....||.|.....| . .|.....|.|. telkeGdrekcaeyw--eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeep--kellkliqvvkqklpqkrsseaf -TKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV .|...||..|..|||.||||. ||. . | ||. ..| ..| | ||..|||||.... . knfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvl |
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Phosphatase | PTPRO.AA | Subfamily.N1.PD | 952-1189 | 37 | 1.3e-59 | 193.2 | In-house | 18-260 (268) | Show / Hide |
Range on Protein: 952-1189 Range on HMM: 18-260/268 Sequence Identity: 37% (93 aa) IPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEeegaDYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYW ... .|.|| || .||| .. ||| ||..| . . |||||. . . ..|| ||||||.| . ||.|| .|.|. ..|| .. ||...|| .|| letreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqyw PFTEEP--IAYGD--ITVEMISEEEQDDWACRHFRINY--ADEMQDVMHFNYTAWPDHGVPTANAaeSILQFVHMVRQQAT--KSKGPMIIHCSAGVGRT | || . . . ..|..||||... . |..... .|.. ..|| || ||| |||.. | ..|.|.. ||. . .. ||..||||||.||. pqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespa--afLkfLfkvresgsLssdvgpavihCsagigrs GTFIALDRLLQHIRDHEF---VDILGLVSEMRSYRMSMVQTEEQYIFIH ||. .| .| .| ... ||| . |.|.||. ..|| .| | gtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsy |
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Phosphatase | PTPRO.AA | Subfamily.N14.PD | 942-1192 | 34 | 4.3e-55 | 178.2 | In-house | 6-270 (275) | Show / Hide |
Range on Protein: 942-1192 Range on HMM: 6-270/275 Sequence Identity: 34% (91 aa) FEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEeGADYINANYIPGYNS--PQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQC .|... .| .| || | |||. ..|||. .||.|.. .|. .|||| | . ..||..||||..| .|||.|| .|.|.|||||. . yeripkkredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmltee NEKRRVKCDHYWPFT---EEPIAYGDITVEMISEEEQDDWACRHFRINYA--DEMQDVMHFNYTAWPDHGVPTA-NAAESILQFVHMVRQQATKSK---- |. . |. .|.| . .. . .| | |. | . . ..... | ..|.|. || ||||||| . | |. |. ||....... eedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvk ---GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV |...|||||||||| | | |.. . | .|| .. .| ||..||| || |... . eskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvl |
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Phosphatase | PTPRO.AA | Subfamily.N_Nematode_1.PD | 964-1192 | 36 | 8.4e-54 | 174.0 | In-house | 28-260 (265) | Show / Hide |
Range on Protein: 964-1192 Range on HMM: 28-260/265 Sequence Identity: 36% (88 aa) CKNRYTNILPYDFSRVRLVsmNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYG- ||||... | .||.| .| .||| |||. |. .| .|.|| .| .||| ||||.| . |||| .. || ..|| .|.| .|.. . dknrykdvgcldknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegeklefke ---DITVEMIS---EEEQDD--WACRHFRINYA-DEMQDVMHFNYTAWPDHGVPTANAAesILQFVHMVRqqatKSKGPMIIHCSAGVGRTGTFIALDRL |||| . |.|. ......| .. . | |...| |||.|||.|. | .|.... || .||||...|||||.||||| .|.. .| kgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadla--alelleavr----gskgPivvhCsaGiGrtGtivaieyi LQHIRD-HEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV ... . .. |. || ..|. | .||. ||.|.|. . ldkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvl |
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Phosphatase | PTPRO.AA | Subfamily.N23.PD | 977-1191 | 34 | 5e-53 | 171.7 | In-house | 117-344 (350) | Show / Hide |
Range on Protein: 977-1191 Range on HMM: 117-344/350 Sequence Identity: 34% (79 aa) SRVRLV-SMNEEEGADYINANYIPGYN--SPqEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTE-EPIAYGDITVEMISEEE .|| | | . .. ||||| |. || ..||||||...| .|||.|| .|.|..|||||. .|. . |||.||| | |. .||..| . |... nrvklqqstqpgqqddyinatylkeltpmsP-pfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrs QDDWACRHFRINY--ADEMQDVMHFNYTAWPDHGVPTAnaAESILQFVHMVRQQA-----TKS----KGPMIIHCSAGVGRTGTFIALDRLLQHIRDHE- . | | .... .. ...|.|...|.|...||| . |..|.|.. |.. |. . |.|.|||||||||||| . .. .. .. segwiervlhlqhndvstvrlvchlhtttWseiGvPks--PedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagng FVDILGLVSEMRSYRMSMVQTEEQYIFIHQC ..|. .|...| | |||..... .. . iiniprvvrrlrqqRkymvqkkvilkklyea |
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Phosphatase | PTPRO.AA | Subfamily.R_Nematode_2.PD | 961-1190 | 30 | 4.7e-51 | 164.9 | In-house | 28-254 (261) | Show / Hide |
Range on Protein: 961-1190 Range on HMM: 28-254/261 Sequence Identity: 30% (72 aa) LNRCKNRYTNILPYDFSRVRLvsMNEEEGADyINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFT-EEPIA |.. |.|| .. . ..|. . ... .. | ||..| . |. .||||||| .|..||| || |.| . ||||.|. ||. ||..|.| . .. . lpkdkhRypdvPCkpetavev--ivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkld YGDITVEMISEEE--QDDWACRHFRINYADE---MQDVMHFNYTAWPDHGVPTANaaESILQFVHMVRqqatKSKGPMIIHCSAGVGRTGTFIALDRLLQ | ..... |.|. .|. | .... . . |.|. |. |||.||| .. . . ...|. ||. |...|||||.|||..||. . | .. lgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPksh--aelfeLlelvk----ksekPivvhCsaGiGRtmafigteylar HIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQ . .. . . .. |.|..|. .|||.|. ... eveadptieltealkelrehRwkgiqtesqlywltl |
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Phosphatase | PTPRO.AA | Subfamily.N20.PD | 952-1192 | 39 | 1.5e-50 | 163.6 | In-house | 16-252 (257) | Show / Hide |
Range on Protein: 952-1192 Range on HMM: 16-252/257 Sequence Identity: 39% (94 aa) IPHFAADLPLNRCKNRYTNILPYDFSRVRLVsmneeEGADYINANYIPGYNSPQEY--IATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDH . . | || |||| .||||| .|| | . |||||.|| | .|| ||||||| | .|||.|||...|..| |.|.| .|| |||| . gefnsgnqpsnreknryrdilpydstrvplg-----kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyh YWPFT-EEPIAYGDITVEMISEEEQDDWACRHFRINY--ADEMQDVMHFNYTAWPDHGVPTanAAESILQFVHMVRQQatKSKGPMIIHCSAGVGRTGTF ..|. . | . . . . | |.. . . | ....| ||||| |. .|.|...... |. .|||..|||||.|||| |...| .. ywpislkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpa--sadsfikyiryarks--hltgpmvvhcsagigrtgvf IALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV | ..|. .|..|| | ||||.||| | .. | lcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydiv |
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Phosphatase | PTPRO.AA | Subfamily.RN.PD | 960-1192 | 35 | 1.2e-48 | 157.1 | In-house | 25-259 (264) | Show / Hide |
Range on Protein: 960-1192 Range on HMM: 25-259/264 Sequence Identity: 35% (85 aa) PLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQ-EYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEpI . | |||....|||| |||.| . ...| ||||| | . . ||||||||..| |||.|| .| . .||.||. .|. .|..||| . . eknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckrywpdeGs-e AYGDITVEMISEEE-QDDWACRHFRINY--ADEMQDVMHFNYTAWPDHGVPTAnaAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH |. |...|| ||. | | . ..| . | | . .||..|||.. | |.|.| | . |...|||.|.||||..|..| .|.. vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPas--aksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvler I-RDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV . . .|| . .| | .|.|..|. |. ..| llkGvkeidiaatlehlrdqrpglvktkdqfefaltav |
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Phosphatase | PTPRO.AA | Subfamily.N_Nematode_4.PD | 964-1192 | 31 | 1.3e-47 | 153.8 | In-house | 28-259 (264) | Show / Hide |
Range on Protein: 964-1192 Range on HMM: 28-259/264 Sequence Identity: 31% (73 aa) CKNRYTNILPYDFSRVRLvsMNEEEGADYINANYIPGYnSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEP-IAYGD ||||..|| | .|| | | . ||| |... .||.|||||.|| .||| || ..| ...||| . |.|| |.| ..| .|. .. dknryadilcidetrvvl--knrdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkfGk ITVEMISEEEQ--DDWACRHFRINYAD---EMQD----VMHFNYTAWPDHGVPTAnaAESILQFVHMVRQqaTKSKGPMIIHCSAGVGRTGTFIALDRLL .. ..|. | . . ... . . | |.... |.|. | | ......|.. |...|...||||||||| |.. .| ..||. yritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPld--aapviklykavkk--kkkekPivvhcsaGvGrtatlvGidyat QHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV ...| .| |.|. |. ||.. |..|. .. irirenseievldivrelramrlkavqshlqflfllvvl |
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Phosphatase | PTPRO.AA | PTPc_motif | 1091-1194 | 46 | 1.9e-46 | 161.56 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 1091-1194 Range on HMM: 1-92/92 Sequence Identity: 46% (51 aa) DVMHFNYTAWPDH-----GVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQY |.|. ||.|||| |||. .|||.|...||. |...|||||.||||||.|.| ..|. |||...| |||..|. |||||||| TVHHYHYTNWPDHVEKDSGVPE----DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQY IFIHQCVQL ||...|.. IFCYRCILE |
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Phosphatase | PTPRO.AA | Subfamily.N_Nematode_6.PD | 962-1192 | 35 | 1.8e-44 | 143.5 | In-house | 24-248 (253) | Show / Hide |
Range on Protein: 962-1192 Range on HMM: 24-248/253 Sequence Identity: 35% (82 aa) NRCKNRYTNILPYDFSRVRLVsmneEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFT-EEPIAY .. .|||||| .| .|..|. .. || ||.. |. .| ||.|| .| ..||||.| . .. |||| . ||. |. .| . . . .. fkdrnrytniqCcdagrlkla----ddedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarki GDI-TVEMISEEEQDDWACRHF-RIN-YADEMQDVMHFNYTAWPDHGVPtaNAAESILQFVHMVRqqatKSKGPMIIHCSAGVGRTGTFIALDRLLQHIR .. || |.....| | || .|| | |... .||||||| .. | |... .|. |.| |...|||||||||||.. . .|. .| tklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvP--dsflsalrllsvvk----kdkkPivvhCsaGvGrtGtlaliliilealr DHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV .| .. |. .| |. |||| ||.. ..|| lpdfqgvkdllvklreerfravqtevqylyalrcv |
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Phosphatase | PTPRO.AA | Subfamily.R_Nematode_3.PD | 966-1194 | 25 | 2.5e-38 | 123.4 | In-house | 27-264 (267) | Show / Hide |
Range on Protein: 966-1194 Range on HMM: 27-264/267 Sequence Identity: 25% (62 aa) NRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSpQEYIATQGPL--------PETRNDFWKMVLQQKSQIIVMLTQCNE---KRRVKCDHYWPFT .|..... . .|| |. |.|.||.. |. . | ||.|. .| . ||.|. |.|....||| ..| . || .|.| drrvevpllektrvvLkgygkrfkddfihAnvvecpng-lklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYypek -EEPIAYGDITVEM--ISEEEQDDWACRHFRINYADEM-QDVMHFNYTAWPDHGVPTAnaAESILQFVHMVRqqatKSKGPMIIHCSAGVGRTGTFIALD .. . ....|. |..| ..| |...... .. | | |..|.....| ....|. ...|. ||| |...|||.|..|..|. | . vdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapee--pkealelikfve----ksktpvvVHCsdGisRsatlaaie RLLQHIRDHE-FVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQL | | .. .|.| |..|.|. | .|||....|. .. lgyqliikskgkldllslikelrkqRagaiqtelelafvilgilk |
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Phosphatase | PTPRO.AA | Subfamily.N_Nematode_5.PD | 962-1192 | 23 | 1.4e-35 | 114.1 | In-house | 25-253 (258) | Show / Hide |
Range on Protein: 962-1192 Range on HMM: 25-253/258 Sequence Identity: 23% (55 aa) NRCKNRYTNILPYDFSRVrlvsMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYG | |||.... .| .|| ....| .||||..| .. ...| || |||.| .|||.||.|.| . .|.|.. .|. ... . |.. .|.. nlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketavsffpletgdylnlg DITVEMISEEEQ----DDWACRHFRINYADEmQDVMHFNYTAWPDHGVPTANAAEsILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIR .... |.. . . . . ... ... ..| |... ||. .. | .. |.. .... |.......|.||.|||..|. . . . . kmfinnrkvevkedekkeytvevlpegcses-vfakvyhlttWkkkkvPdkvkkv-ikraiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqln DHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV ..| .. ..|| |. .|.. || .....| ngkepnideilkkirsqRpgavesliqyasvyaav |
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Phosphatase | PTPRO.AA | Subfamily.N_Nematode_egg.PD | 962-1193 | 26 | 1.8e-29 | 94.3 | In-house | 26-253 (257) | Show / Hide |
Range on Protein: 962-1193 Range on HMM: 26-253/257 Sequence Identity: 26% (61 aa) NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKrrVKCDHYWPFTE-EPIAY .. | | . ..|||.| . |.| ||.. | .|.| .| || .| .|||.|| |.| | ||||| |.|..||| .| |.. . | ylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyywpkaeseslvt --GDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWpDhgVPTANAAESILQFVHMVRQQATkskgPMIIHCSAGVGRTGTFIALDRLLQH-IR . .| . ... | | ... .. .. .. . | | .. | |. ...|. .. |..... || ...|..|.. | . .| . vpGslrienlkvdskadplfrvtklklvGgddeelflehwqg-d--vnylsdvysplrvlrklrnlsk----pvvvqdilGvskaatlvaieiallsllr DHEF-VDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQ .| | .| | |.. .|.|... | Gpitkslvlravvflrlrrrlsvesvllylfvyrlvl |
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Phosphatase | PTPRO.AA | Subfamily.N_Fungi_PTP1.PD | 964-1072 | 41 | 1.3e-27 | 88.1 | In-house | 47-165 (343) | Show / Hide |
Range on Protein: 964-1072 Range on HMM: 47-165/343 Sequence Identity: 41% (51 aa) CKNRYTNILPYDFSRVRLV-S-------MNEEEGADYINANYIPGY------NSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDH .||||.|||||. |||.| | .. |||||||. |. |||||.|||.| .||.|..|. | ..|..||. | . ||.. aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr YWPfteePIAYGDITVEMISEEE ||. .| |||| . | | YWq----egsydditvklaskwe |
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Phosphatase | PTPRO.AA | Subfamily.N_Nematode_eak.PD | 965-1108 | 30 | 6.8e-20 | 62.9 | In-house | 29-172 (281) | Show / Hide |
Range on Protein: 965-1108 Range on HMM: 29-172/281 Sequence Identity: 30% (43 aa) KNRYTNILPYDFSRVRLVSMNEEeGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDIT .|| .|.|.|. ||| | . |||| . . ..|| | . . ||.|||.||| ||.| . |..| | |.| | . || . || rnrvvkivpqdrylvrltssqln-rdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevlkyGild VEMISE-EEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTA . ... | . .. .| |.|... | . .| verkeyavkrniletrllilrkGnethrvlhykvfGwtettlpky |
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Phosphatase | PTPRO.AA | Subfamily.N_Fungi_PTP1.PD | 1088-1194 | 31 | 7.3e-19 | 59.3 | In-house | 211-340 (343) | Show / Hide |
Range on Protein: 1088-1194 Range on HMM: 211-340/343 Sequence Identity: 31% (39 aa) EMQDVMHFNYTAWPDHGvpTANAAESILQFVH---------MVR-QQATKSKGPMIIHCSAGVGRTGTFIALDRLLQH------IRDH--------EFVD | |..... |.| . . . ||||| . . . .. |...|||||||||||...|| ||...... . | | .| epyevyqlqvknWkDls--lllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrD -ILGLVSEMRSYRMSMVQTEEQYIFIHQCVQL |.|. |.||||. .|.|||..... lisiivnelrkqrismvqnldqfifiYeallf |
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Phosphatase | PTPRO.AA | Family.DSP.PD | 1080-1202 | 20 | 4.8e-12 | 37.3 | In-house | 148-253 (387) | Show / Hide |
Range on Protein: 1080-1202 Range on HMM: 148-253/387 Sequence Identity: 20% (23 aa) HfrinyadeMQDVMHFNYtAWPDHGVPTANAAesILQFVHMVRQQAtKSKGPMIIHCSAGVGRTGTFIALDRLLQhiRDHEFVDILGLVSEMRsyRmSMV ... . .. ...||..|. . . ... . .. .||| .|| ||.||.|| |. .. . .. .. . | .|.. |. .... ... |..| k--------elgikylri-pidDhnapplenl--fekaidfieegn-dskgvVlVHCkaGkgRsgtliiaYlmks--egltleealdwvrskR--p-gvi QTEEQyiFIHQCVQLMWMKKKQ--Q .|. .| |. . tpnqg--flkqlkdlekeklkvsse |
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Phosphatase | PTPRO.AA | Subfamily.PTPDC1.PD | 1090-1193 | 28 | 1.3e-11 | 35.8 | In-house | 133-225 (229) | Show / Hide |
Range on Protein: 1090-1193 Range on HMM: 133-225/229 Sequence Identity: 28% (29 aa) QDVMHFNYtAWPDHGVPTAnaaESILQFVHMVRQQAtkSKGPMIIHCSAGVGRTGTFIALdrLLQHIRDhefVDILGLVSEMRSYRMSMVQTEEQYIFIH |.....|. ...|.||.. |.||. | .| . ..| . .|| || |||| || | . .. .. .. .|| |.|| || .... qgiyfynf-glkDygvasl---eriLdivkvvdfal--eegkiavHCHAGlGRtGvliac--ylvyakr---ltaeeaiklvrskrpksiqtreqvelve QCVQ . eFal |
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Phosphatase | PTPRO.AA | Subfamily.DSP23.PD | 1110-1185 | 30 | 8.9e-09 | 26.9 | In-house | 48-117 (128) | Show / Hide |
Range on Protein: 1110-1185 Range on HMM: 48-117/128 Sequence Identity: 30% (23 aa) AAESILQFVHMVrQQATKSKGPMIIHCSAGVGRTGTFIALdrLLQHIRDHEFVDilgLVSEMRSYRMSMVQTEEQY | | . ..|..| ..| |..... .|| |.|||||..| | . .. | . |.| | ..| || aleqvarlvriv-eeaekkeeavgvhcalGlGrtGtllac--ylvkeeglaadd---aiaevrkrrkGsietveqe |
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Phosphatase | PTPRO.AA | Subfamily.CDC14.PD | 1124-1155 | 45 | 1.1e-06 | 19.9 | In-house | 193-223 (258) | Show / Hide |
Range on Protein: 1124-1155 Range on HMM: 193-223/258 Sequence Identity: 45% (14 aa) QATKSKGPMIIHCSAGVGRTGTFIALdRLLQH . |..| ...|| ||.|||||.|. |..| itekaeGaiavhCkaGLGrtgtligc-ylikh |
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Phosphatase | PTPRO.AA | Subfamily.PTEN.PD | 1091-1149 | 29 | 7.6e-06 | 16.9 | In-house | 61-114 (305) | Show / Hide |
Range on Protein: 1091-1149 Range on HMM: 61-114/305 Sequence Identity: 29% (17 aa) DVMHFNYTawpDHGVPTANAAESILQFVHMVRQQatKSKGPMIIHCSAGVGRTGTFIAL |... . || || . |.| . |.. .. .. ...|| || ||||. |. rvavypfd---DhnpptleLleeivedvdkwLke--dksnVvavHCkaGkGRtGvmica |
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Phosphatase | PTPRO.AA | Subfamily.N_Nematode_eak.PD | 1112-1192 | 24 | 9.9e-06 | 16.4 | In-house | 194-276 (281) | Show / Hide |
Range on Protein: 1112-1192 Range on HMM: 194-276/281 Sequence Identity: 24% (20 aa) ESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIR--DHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCV .| | . . . | || .. | |.|.|. .| |.. | .. . |. ..| |. | .. |. ||.. | ksallrstlkkyihtppsfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeiv |