PTPRC
Species: Human
Alias: LY5, GP180, CD45, CD45R, PTPRC, LCA, T200, B220
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RC
Protein domain

Protein domains of PTPRC.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PTP_N PTPRC.AA PTP_N 5-32 71 2e-12 47.03 Pfam 1-28 (28) Show / Hide
Range on Protein: 5-32
Range on HMM: 1-28/28
Sequence Identity: 71% (20 aa)

LKLLAFGFAFLDTEVFVTGQSPTPSPTG
||.|||||||||..||||.||.||...|
LKTLAFGFAFLDPHVFVTHQSQTPPTQG

CD45 PTPRC.AA CD45 234-294 75 2.5e-39 134.1 Pfam 1-62 (62) Show / Hide
Range on Protein: 234-294
Range on HMM: 1-62/62
Sequence Identity: 75% (47 aa)

TVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKN-ASVSISHNSCTAPDKTLI
||||||.|.||||||||||||||.|.||.||||..|||.||.. ..||||||||||||||..
TVDYLYDKNTKLFTAKLNVNENVKCENNDCTNNMLHNLQECEQIRNVSISHNSCTAPDKTIK

PTP_N PTPRC.AA PTP_N 33-60 21 4.1e-08 31.99 Pfam 1-28 (28) Show / Hide
Range on Protein: 33-60
Range on HMM: 1-28/28
Sequence Identity: 21% (6 aa)

LTTAKMPSVPLSSDPLPTHTTAFSPAST
|.|.......|......||.....|...
LKTLAFGFAFLDPHVFVTHQSQTPPTQG

Phosphatase PTPRC.AA Subfamily.RC.PD 650-912 53 1.4e-143 468.8 In-house 1-288 (288) Show / Hide
Range on Protein: 650-912
Range on HMM: 1-288/288
Sequence Identity: 53% (155 aa)

LFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVEL-------------------SEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDET
|..||||..|.|.||..||.|||..|..||||.|.||||||||||                   ..|....||.|||||.||..|.|.||||||||..||
lleaefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplket

VDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWpsmEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATgREVTHIQFTSWPDHGVPEDPHLLL
||||||||.|.|..||||.|...||.|.||||||   |||.||.|||.|.........|||..||..||||.|.. ||||.||.|||.....||.|..||
vddfwrmiferkvkvivmltelkeGdrekcaeyw---eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkds-revtqiqytswsveqlpeepkell

KL----------RRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQ
||          .|...||.||.|.|..|||..|..|||..|...|.||.||||.||||...|.|||..|.|||.||.||||....|||..|
kliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvetyq

Phosphatase PTPRC.AA PTPc 650-912 35 5.6e-128 432.39 SMART 1-308 (308) Show / Hide
Range on Protein: 650-912
Range on HMM: 1-308/308
Sequence Identity: 35% (113 aa)

LFLAEFQSIPRVFSKF---------PIKEARKPFNQ--NKNRYV-DILPYDYNRVELSEINGD----AGSNYINASYIDGFKEPRKYIAAQGPRDETVDD
 | .||....|....          ....|..| |.  .||||  ||..||..|| |. ..|.     ||.||||.||||...|..||..||| ..|..|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMIWEQKATVIVMVTRCEEG--------NRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCP-DYIIQKLNIVNKKEK-------ATGREVTHIQFTSW
||||.|.|| ..||| ..|.|.        .|.||. |||.    .  .|.  |..   . || ||.. .... |....          |.|||...|.|
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE---PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNW

PDHGVPEDPHLLLKLRRRVNAFSNFF-------------------SGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEA
|||||||.|. .|...|.|.. .. .                   .||||||||||.|||||...||.|.. .|.   ||... | ..| ||. ||| |.
PDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEE

QYILIHQALVEYNQ
||| ..... || .
QYIFCYRCILEYIK

Phosphatase PTPRC.AA Y_phosphatase 675-909 46 4.2e-126 430.03 Pfam 1-243 (243) Show / Hide
Range on Protein: 675-909
Range on HMM: 1-243/243
Sequence Identity: 46% (113 aa)

NQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDG-FKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNR-NK-CAEYWPS-MEEG
|..||||.||..||..|| |. |.|| .|.||||.|||| ...|..||..||| ..|..|||||.|.|| |.|||...|.|..| .| |..|||.  |..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

TRAFGDVVVKINQHKRCPDYIIQKLNIVNKKE-KATGREVTHIQFTSWPDHGVPED-PHLLLKLRRRVNAFSN-FFSG--PIVVHCSAGVGRTGTYIGID
.  .||  |..   . ||||.. .... | .. |   |.|||...|.||||||||. |. .|...|.|. ...   .|  |||||||||.|||||...||
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAID

AMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVE
.|.. .|.|..||....| ..|.||. ||| |.||| ..|...|
IMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase PTPRC.AA Subfamily.R_Anemone_2.PD 651-910 44 6e-97 315.7 In-house 2-260 (262) Show / Hide
Range on Protein: 651-910
Range on HMM: 2-260/262
Sequence Identity: 44% (117 aa)

FLAEFQSIPRVFSK-FPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMV
. .|.. . |. .. . .|.| .| |..||||..||.||  ||.|....|. ||.||||.||||... ..|||.|.|  ||..|||||.|||...||||.
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TRCEEGNRNKCAEYWPSmeEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATgREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFS-NFFSGPIV
|..||  . |.. ||||  .|.|..|..||........ ||....... ...|... |.|   ..|||||.||||..  ||.| |.|..   .   ||||
tqeeergkakvhryWPs--kgsrsygklvvelkeevelsdyvlrsfkvkrteeeee-rqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpiv

VHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
|||||||||||..| .|..|| ..||. |||...| .||.|| ||||.. ||..|...|.|.
vhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvllea

Phosphatase PTPRC.AA Subfamily.RB.PD 652-910 46 4.7e-96 312.6 In-house 3-259 (261) Show / Hide
Range on Protein: 652-910
Range on HMM: 3-259/261
Sequence Identity: 46% (118 aa)

LAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTR
|.... .| .. ..|.|... |..|||.  |||||..||.|.... .....||||.||.|.. ||.|||.|||  |||||||||.||.|...|||.|.. 
seeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltq

CEEGNRNKCAEYWPSMEEgTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEkatGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSN--FFSGPIVV
|. ..|| ||||. || . ..||. |.....|.  ...|....| ..||    |.|.. .|||||||||||... ||.. |.|..    ..|||||||||
lvEkgkekceeYWPadee-pvlyGdikvtllaekeldewvirefkiekgke---krkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivv

HCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
||||||.| .| .|. .|... |||.| |..||..|.|.|| |.|||.||..|...     
HCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl

Phosphatase PTPRC.AA Subfamily.RA.PD 653-910 45 1.4e-92 301.2 In-house 4-264 (266) Show / Hide
Range on Protein: 653-910
Range on HMM: 4-264/266
Sequence Identity: 45% (120 aa)

AEFQSIPRVFSK-FPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTR
||.... |  .   .. | |. |..|||.|.|||||..|| || ..|   |.|||||.|||..|  |.||||||..|||.||||||||||..|||.|  .
eefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmlte

CEEGNRNKCAEYWPSmeEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNK---KEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSG-PI
| ...|||.|||.  ||. ..|.. |...... . || .... . ..   ... . | |. . |||||. ||| ..  .||| ..|..  .  .. ||||
lkerkeekcaqywpd--eGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpi

VVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
|||||||||||.| .||.|| ..||.|.||.. | .|| ||. ||| . || .|...| ||  
vvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlley

Phosphatase PTPRC.AA Subfamily.R_Sponge_2.PD 664-910 44 2.6e-90 293.9 In-house 14-260 (262) Show / Hide
Range on Protein: 664-910
Range on HMM: 14-260/262
Sequence Identity: 44% (111 aa)

KFPIKEARKPFNQNKNRYVDILPYDYNRVELSEiNGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEY
.| ...|... |. |||...||||| .||.|.. .|  .|.|||||..||.|..  |||.|||  |||.|||||.||.| . |||.|  || ...|||.|
efslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakY

WPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRV-NAFSNFFSGPIVVHCSAGVGRTGTYI
||. ....  .|...|....... .||||.||.. ..|...  ..||. .|..||.|.||.|   ||.| .|| .|  .  ...|.|.||.|||||||.|
WPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfi

GIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
 .|..|| |.||...||. .. .|| .|  .|| .|||  ||.|| ||
aldsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalley

Phosphatase PTPRC.AA Subfamily.R_Anemone_1.PD 653-910 44 1.4e-87 285.1 In-house 4-256 (258) Show / Hide
Range on Protein: 653-910
Range on HMM: 4-256/258
Sequence Identity: 44% (116 aa)

AEFQSIPrVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRC
|||| .     ..  . |||. |..|||| ||...|  || |.. ..|  |.||||||...... |..||.|.|  |||.|||||.|..|..||||.|  
aefqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnl

EEGNRNKCAEYWPSmeeGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKaTGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCS
.||. .|| .|||.   .|...|.. |......   ||||..| . .|||. . |||....||.|||.|||.    .|.|||.|.. |.  . |.|||||
iegekkkchqYwPd---stekygelrvslrkkevfadyiirtlvlskkket-eerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCs

AGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
|||||||... |||||| . .|. ||.. || ..|..|. ||| . ||. ||.|..|.
aGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavlea

Phosphatase PTPRC.AA Subfamily.R_Ecdysozoa.PD 651-911 42 2.8e-85 277.2 In-house 2-268 (269) Show / Hide
Range on Protein: 651-911
Range on HMM: 2-268/269
Sequence Identity: 42% (115 aa)

FLAEFQSIP-RVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMV
.  |..... |....   | . |  |. |||| || ..| .|| |..|||.. |.|||||.| |.|| .|.||||.| ..|..||||||.||. |.|||.
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml

TRCEEGNRNkCAEYWPSMeeGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKA--TGREVTHIQFTSWP-DHGVPEDPHLLLKLRRRVNAFSNFF---
.  .| ||. || |||     .  .||..||. ... ..||||..|.. .|||..    |.|.  ..|.|. |  ||| .. |||| ..|. . ..    
snlteknrk-cakyWpie--devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnkls

--SGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYN
   .||||||||||||.|... .| .|. |.||.|||.. .| |||.|| |.||.||. ...||..|.  
gsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyraladys

Phosphatase PTPRC.AA Subfamily.RG.PD 653-910 37 7.8e-81 262.8 In-house 4-262 (264) Show / Hide
Range on Protein: 653-910
Range on HMM: 4-262/264
Sequence Identity: 37% (96 aa)

AEFQSIPRV-FSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTR
..|. | ..  ...... ..|. |..|||...|....  ||.||.. |  |..|||||||||..  ..||..|||  ||..||||||||..|..|||.| 
eqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltd

CEEGNRNKCAEYWPSMeEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGR-EVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVH
 .|  |.... |||.  ...  .... |.. ....  .|..... . |.| .   . .|.. ..|.|||.|.||     |   .. .|.  .||||||.|
ldekgrrdedvyWPkk-deplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivvh

CSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
|||||.|||| .|..|. ||.|..|.||... ..| .|  .|. | ||. |..||.|   
dsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel

Phosphatase PTPRC.AA Subfamily.N9.PD 667-911 46 1.5e-80 262.0 In-house 18-274 (275) Show / Hide
Range on Protein: 667-911
Range on HMM: 18-274/275
Sequence Identity: 46% (110 aa)

IKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPS
.. .... | .|||| |.| ||  || |.....|  |.||||...||.|... .||.||| ..||.|||||.|||.. ||||.||..| .| ||..|||.
flasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywpl

MEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATgREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNF-------------FSGPIVVHCSA
 || .  |||. |.  . .   || ...|.| | |.. . |.||| ||.||||.|||.. . ||.....||||||||||.|||||.| .|  |. || ..
eeessaefgdlsvsnveveveedykvrvleiknvktees-rkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsa

GVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYN
.|||   | .|| ||  ..|.. || . ..|..||                       
GiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya

Phosphatase PTPRC.AA Subfamily.N12.PD 663-910 44 5.6e-80 259.8 In-house 20-268 (270) Show / Hide
Range on Protein: 663-910
Range on HMM: 20-268/270
Sequence Identity: 44% (111 aa)

SKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAE
.... ....|. |..|||| ||||||..|||||.|... ||.||||..| | ... .|||||||  .|.|||||||||.. ...||. |  |...||. |
kvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCer

YWPSMEEGTRAFGDVVVKINQHKRCP-DYIIQKLNIVNKKEKatgREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTY
||.  | .  ||.. |. ...|..  |..|. |.. ..||.   |.|. ...|.|||||||. .. ||.| . |. . .  . |.||||||||||||| |
yWpeegeeelefgefevtleeekavdddflirtLkveaqkes---rkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGti

IGIDAMLEGLEAEN---KVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
 || . | |.||.   ..||.  |..||.||  .|| . || |...|..|. 
iaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael

Phosphatase PTPRC.AA Subfamily.N_Choan_1.PD 651-910 37 6.9e-79 256.4 In-house 2-260 (262) Show / Hide
Range on Protein: 651-910
Range on HMM: 2-260/262
Sequence Identity: 37% (98 aa)

FLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVT
|  |....  .  . . . .... |..||||..|  ||  ||.... . .  ..||||....|.|....|||.|||  .....||.|.||||...|||||
fieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvt

RCEEGNRNKCAEYWPsMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIvnKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSN-FFSGPIVV
|  |... ||  |||  |. .  .|||.|| ..... . || .|...  ..|..  |||.....|.|||||||.... ||. |. |. ...     |.|.
reieagklkChryWP-denselklgdvtvkslseeekktyierkfkl--eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvi

HCSAGVGRTGTYIGIDAMLEGLEAENKV-DVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
|||||||||||||..| ... .|..... ||   | .||..| ||||  .||  ...|. ..
hCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavlda

Phosphatase PTPRC.AA Subfamily.RK.PD 654-910 38 5.8e-77 249.9 In-house 5-265 (267) Show / Hide
Range on Protein: 654-910
Range on HMM: 5-265/267
Sequence Identity: 38% (101 aa)

EFQSIPRVFSKF---PIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDaGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVT
||...  |  .     .. | |. |..|||. |||.||  .| |  ..||  |.||||..||..| |...|..||| .||| ||||........|||.| 
efetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlt

RC-EEGNRNKCAEYWPsmEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVN-KKEKATGREVTHIQFTSWPDH-GVPEDPHLLLKLRRRVNAFSNF-FSGP
   |  | || .|||  |...  .||. |.. . .   |.... ... .  . .   ||| ..||..||.. .||.  . |||| |||.. ..    |.|
eldvevgrvkClkyWP--edtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGr

IVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
||||.|| ||.||.| || .|| .| |. |||.  | .|| ..  ||..| ||...... .|. 
ivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvilea

Phosphatase PTPRC.AA Subfamily.N5_RR.PD 653-911 41 2.8e-76 247.8 In-house 4-264 (265) Show / Hide
Range on Protein: 653-911
Range on HMM: 4-264/265
Sequence Identity: 41% (111 aa)

AEFQSIPRVFskfPIKEARKPFNQNKNRYVDILPYDYNRVEL-SEINGDAGSNYINASYIDGFKEP-RKYIAAQGPRDETVDDFWRMIWEQKATVIVMVT
.|| ..|  |   . .| . . .|.|||| .||| .  || | || . |  |.|||| || |..|  . |.|.|||  .|..||||||......||||.|
keflelPlnf---sqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmlt

RCEEGNRNKCAEYWPSMEEG--TRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEkaTGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAF---SNFFSG
. .| ||.|||.|.|  |.   .  .||| .|... ... || ..|| . . ..    |.|.|. .|.|||| .|.|.. ||.| . |.     .|   .
klkeanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkyler--versvkhywytdWPdhksPddintlldlvleveesreeenakla

PIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYN
|.|||||||.|||| .|.|.  .  |..|..||| . |..|| .|  ||| . || |||.||..| 
PvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl

Phosphatase PTPRC.AA Subfamily.N3.PD 652-909 39 6.2e-73 236.6 In-house 3-258 (261) Show / Hide
Range on Protein: 652-909
Range on HMM: 3-258/261
Sequence Identity: 39% (103 aa)

LAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGdagsNYINASYI----DGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIV
||.|... |    . |..|||| | .|||| ||||||  ||.|.| .     .||||.|.    ....   .|||.||| ..|. |||.|.||||.|.||
laqfeelyrkkpglaisaarkpenlaknryrdilpydatrvklkeset----dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstliv

MVTRCEEGNRNKCAEYWPSMEEgTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKaTGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPI
|.|   |  | || .|||..|. .  ||.. |.......   |....| . .|..|   |.....|...|||||||.|.. .|.. .||..  .  . |.
mlttlverGrvkChqyWPeted-elefgefsvrcekedetksyvlrelvlkdketk-eerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePv

VVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVE
|||||||.|||| .| ..  |  .||...| .   | ..| ||  .|| ..|| .. .|...
vvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailk

Phosphatase PTPRC.AA Subfamily.N_Choan_2.PD 675-911 42 1e-72 235.9 In-house 21-265 (266) Show / Hide
Range on Protein: 675-911
Range on HMM: 21-265/266
Sequence Identity: 42% (105 aa)

NQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFK-EPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRA
|.. ||| ||||    || |.|.. |  ..|||| |. ||. |..|||||.|| . |. .|||||||.|.| |||.|  || .|.||. |||.  . . .
nkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk

F--GDVVVKINQHKRCPDYIIQKLNIVNKKEKatgREVTHIQFTSWPDHGVPEDPH------LLLKLRRRVNAFSN-FFSG-PIVVHCSAGVGRTGTYIG
.  |.. |   ....   ||...|.. .|.|.   |...| ....|||||||...        |||. | |..... .  . |..|||||||||||| | 
ladgkikvlalseekeegyiltrlrlekkget---rrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtlia

IDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYN
|| ... || ..||||   . .||..|. .||   || |...|.||| 
iDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya

Phosphatase PTPRC.AA Subfamily.N6.PD 654-910 38 1.5e-72 235.8 In-house 17-293 (295) Show / Hide
Range on Protein: 654-910
Range on HMM: 17-293/295
Sequence Identity: 38% (106 aa)

EFQSIP--RVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEI-NGDAGSNYINASYID--------G--FKE---PRKYIAAQGPRDETVDDFWRM
||...    . ...  ||..|. |..|||| .|||.| .|| |..  .  .||.||||.||.        |  ..     ..|||.||. ..|||||||.
efeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrm

IWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRaFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVN
|.....||||.|.  | ..|||| |||. |. .. .|.. |.  . |   ||.. .... .|... . ||. . .|..|||||||.||  .|.. . ||.
vwqensrvivmttkevergknkCarYWPdeetkke-tGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvn

AFSNFF--SGPIVVHCSAGVGRTGTYIGIDAMLEGLE---AENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
 .. .  .||||||||||.|||||.| ||..|. .|   .. ..|..  . ..|.||  .|| ||||. . .|.  | 
kkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfy

Phosphatase PTPRC.AA Subfamily.N13.PD 654-909 38 8.4e-70 226.6 In-house 5-256 (259) Show / Hide
Range on Protein: 654-909
Range on HMM: 5-256/259
Sequence Identity: 38% (101 aa)

EFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGdagsnYINASYIDG--FKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTR
||. .  . ..   ....|  |..|||| ..||||  ||.|..  |     |||||.|     ..  .|||.|||  |||.|||.|.|||||.||.||| 
efkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtl

CEEGNRNKCAEYWPSMEEGTRAFGD-VVVKINQHKRCPDYIIQKLNIVNkKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNfFSGPIVVH
  |... ||  |||. .. .    . . |.  . ..  .. ...|.. . .| .  |||.|..|..|||||||  .  |... ..|. . .  .||||||
ekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkd-sesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPivvh

CSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVE
||||.||.|..| ||..|. .| ....||   | |||.||  .|| . |||....|..|
csaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile

Phosphatase PTPRC.AA Subfamily.N14.PD 653-910 37 2.9e-65 211.6 In-house 4-273 (275) Show / Hide
Range on Protein: 653-910
Range on HMM: 4-273/275
Sequence Identity: 37% (101 aa)

AEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDaGSNYINASYIDGF--KEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVT
.|.. ||.   .  .. |. | |..|||. |.|||. ||||||  . .  ..||||| |      . |.||.|||| ..|| |||.|.|||...|||.|.
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlt

RCEEGNRNKCAEYWPSM--EEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKeKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNA-------FSN
 ||. ..|. .|.|..  .. |  ||   |  . ..  . .| ..|..         |.| |.|.| |||||||||.. .|.  ..|..        .. 
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlp-skeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseve

---FFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
    . |..|||||||||||  |  | ... || ....|.   . .||.|| |.||  ||| .....|..| 
svkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvliky

Phosphatase PTPRC.AA Subfamily.RN.PD 669-909 41 2.8e-59 191.9 In-house 21-261 (264) Show / Hide
Range on Protein: 669-909
Range on HMM: 21-261/264
Sequence Identity: 41% (101 aa)

EARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGfKEPRK--YIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPs
|... | .|||. ..|||| .||.|.| . .  |.||||| |   ..||.  |||.|||  .|. |||.|.||| ..|||..|| || . ..|..|||  
vakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaild-hdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckrywp-

mEEGTRAFGDVVVK-INQHKRCPDYIIQKLNIVNKKEKATgREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGID
.||.  ..   |. . .|  | ||... . . | . . | | ||   | |||..|||  .. ||..||.||      | |||||||.|.||||.|| || 
-deGsevyhiyevhlvsehiwcddylvrsfylknlqtset-rtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilid

AMLEGLEA-ENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVE
.|| |    ...|.   . .|| ||  .|. ..|. .. .|..| 
lvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae

Phosphatase PTPRC.AA Subfamily.N_Nematode_1.PD 653-910 34 5.4e-56 181.2 In-house 4-263 (265) Show / Hide
Range on Protein: 653-910
Range on HMM: 4-263/265
Sequence Identity: 34% (91 aa)

AEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEinGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRC
.||... .  ..  .|  ..  ...|||| |.   | ||| |.|  . . |.|| | |.    .|...| ||.| |.|..||||.  .|   |||. .. 
defralkkfndeekvkafkeaqeadknrykdvgcldknrvklae--eplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckl

EEGNRNKCAEYWPSMEEGTRAFGDV----VV-KINQHK-RCP-DYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFsnffSG
|  . |||||.|. |. .  | .     .| .  . | . . . .|.. ..  .    . |.|||.|.| |||.|||.     |.|  .|..      ||
iekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgs----kg

PIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVD-VYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
||||||||.||||| ..|. .|. | ...... .   | |.| ||   .|.|||. .|. |..|  
PivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllny

Phosphatase PTPRC.AA Subfamily.N23.PD 688-910 35 1.5e-54 176.8 In-house 115-348 (350) Show / Hide
Range on Protein: 688-910
Range on HMM: 115-348/350
Sequence Identity: 35% (83 aa)

DYNRVELS-EINGDAGSNYINASYIDGFK-EPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHK
| |||.|    .    ..||||.|.        ..||.|||  .|. ||| |.|||.. ||||.|. .|||. ||..|||  |. |  |||.| ... . 
dpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslr

RCPDYIIQKLNIVNkKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFS---------NFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENK
 . .| ..|..   ..  | |.|.|...|.|...|||. |  ||..   |..           .    ||..|||||||||||.. . .. |.|.| . .
ssegwiervlhlqh-ndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagng

V-DVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
.   | .||.||  ||| ....  . .| .|.   
iiniprvvrrlrqqRkymvqkkvilkklyeavlea

Phosphatase PTPRC.AA Subfamily.N1.PD 664-909 33 1.1e-53 173.8 In-house 17-265 (268) Show / Hide
Range on Protein: 664-909
Range on HMM: 17-265/268
Sequence Identity: 33% (86 aa)

KFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGdagsNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEY
... .||..| |...||| |. |||. |..| . .     .||||| ..  .  |.|| .|||  .|.| ||.|.|||..  ..|. .. | |..|||.|
eletreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqy

WPSMEEG-TRAFGDVVVKIN--QHKRCPDYIIQKLNIVNKKEKATgREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNF--FSGPIVVHCSAGVGRT
||. ||  .  . ..  |..  ...|   .. ..|.. ..... | ||..| ..| ||| |||| | ..||.  .|     .    ||.|.|||||.||.
wpqeeeeaellleetklkvkliseerksyflvrlleLedletqet-reilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrs

GTYIGIDAMLEGLEAENK---VDVYGYVVKLRRQRCLMVQVEAQYILIHQALVE
||.  .|..|  .|....   ||.   ...||..|  ..|   |     .|..|
gtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile

Phosphatase PTPRC.AA Subfamily.N_Nematode_4.PD 675-910 34 1e-51 167.3 In-house 26-262 (264) Show / Hide
Range on Protein: 675-910
Range on HMM: 26-262/264
Sequence Identity: 34% (84 aa)

NQNKNRYVDILPYDYNRVELSEINGDagSNYINASYIDGFkEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAF
|..|||| |||  | .|| | . . |   .|| ||..    .  .||..||| .||..||| |....|..|.||.   .|.. .||| |.|. .| .  |
nsdknryadilcidetrvvlknrdpd--ndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkf

GDVVVKINQHKR--CPDYIIQKLNIVNKK--EKATG--REVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAfsNFFSGPIVVHCSAGVGRTGTYIGIDAML
|.  ... ..|     | |.. |...| .   .|.     | |.|.. |.|.  |.|.  ..|| . |.   .  ..||||||||||||| |..|||   
GkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrtatlvGidyat

EGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
  .   ....|   | .||  |   || . |.. .   |.|.
irirenseievldivrelramrlkavqshlqflfllvvliel

Phosphatase PTPRC.AA Subfamily.N6.PD 937-1224 28 2.1e-51 166.4 In-house 9-291 (295) Show / Hide
Range on Protein: 937-1224
Range on HMM: 9-291/295
Sequence Identity: 28% (84 aa)

SEPSPLEAEFQRLP--SYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEpskyiNASFIMSYWKPEVMIAAQ
|.   .. ||..|     ..  ... |.. |||.|||  |..|.| .|| ||   .  . |.    .  . .. |.      ...   |  ..  ||.||
sqtlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkasks-----sgenveseehqkryiatq

GPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGE--GKQTYGDIEVDLKDTDKSSTYTLRVFELRHS-KRKDSRTVYQYQYTNWSVEQLPAE
.||.|. |||.|..| . .||||.|.     .. ||.|| .   |...|.|.|   . .. ..|||| |.. |  | |..|...||....|     |..|
gcLkdtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkd

PKELISMIQVVKQKLPQKnssegnkhHKSTPLLIHCRDGSQQTGIFC---ALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIA
. ...... |..|  .         .|. |...|| .|  .|| |    ..|...|.  ..  .|| ...| .|.| |.| | .||.|.| ...  
pgvvlnfledvnkkqeel--------ekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq

Phosphatase PTPRC.AA Subfamily.N20.PD 669-908 37 9.7e-50 161.0 In-house 20-253 (257) Show / Hide
Range on Protein: 669-908
Range on HMM: 20-253/257
Sequence Identity: 37% (90 aa)

EARKPFNQNKNRYVDILPYDYNRVELSEingdaGSNYINASYIDGF--KEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPS
.| |..|||| ||||||  || | .       .|||||||      |   |||.|||   |.||||.|. |... || |.||  ||   ||  |||   .
sgnqpsnreknryrdilpydstrvplgk-----skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpi

MEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKkEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRvnAFSNFFSGPIVVHCSAGVGRTGTYIGIDA
    .  . | .....    .||. ...|.|    | . | ..||| ||||| |     ..|  |   |  ....||.|||||||.|||| .. .| .. 
slkkplelkhfrvflenyqilqyfiirmfqvvek-stgtshsvkqlqftkwpdhgtpasadsfikyiry--arkshltgpmvvhcsagigrtgvflcvdv

MLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALV
 .  .  ...   | ..| ||. ||| . || . .. ..   
vfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivl

Phosphatase PTPRC.AA Subfamily.N_Nematode_6.PD 675-910 33 1.3e-49 160.3 In-house 24-251 (253) Show / Hide
Range on Protein: 675-910
Range on HMM: 24-251/253
Sequence Identity: 33% (78 aa)

NQNKNRYVDILPYDYNRVELSeinGDAgSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAF
....||| .|  .|  |..|.   .|    || |....  ..||..| .|.| ..|...||.||  .  . |||.    |  ..|.||| ..    .| .
fkdrnrytniqCcdagrlkla---dde-dfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarki

GDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLrrrVNAFSNfFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAE
...  .|.  ..  | |...  ..  |.      | ||.. .|||||||..    |.|   .... .||||||||||||||| . |  .|| |   .. .
tklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrl---lsvvkk-dkkPivvhCsaGvGrtGtlaliliilealrlp

NKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
|   .||||..|   ||.| ||.  .. ..||    
dfqgvkdllvklreerfravqtevqylyalrcvley

Phosphatase PTPRC.AA Subfamily.R_Nematode_2.PD 666-908 29 1.3e-48 156.9 In-house 20-257 (261) Show / Hide
Range on Protein: 666-908
Range on HMM: 20-257/261
Sequence Identity: 29% (73 aa)

PIKEARKPFNQNKNRYVDILPYDYNRVELSeINGDAGSnyINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWP
..|  .  ...|.|| |.   .  .||   ..| .    | | ...  ..|...||.||| ..|..||| |.  .|   |||.... | ...||.||.|.
svtesaaylpkdkhRypdvPCkpetavevi-vdgkrvp--ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfp

SMEEGTRAFGDVVVKINQHKR-CPDYIIQ-KLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNffsgPIVVHCSAGVGRTGTYIG
 .. .  .| . .|. ....  .| | . .|...... | . | ||| |...|||.|||.    | .|   |    .    |||||||||.|||...||.
letsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek----PivvhCsaGiGRtmafig

IDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALV
. . . .||.... .   . .|| .|   .| | |.  .. ... 
teylareveadptieltealkelrehRwkgiqtesqlywltlgal

Phosphatase PTPRC.AA PTPc_motif 808-909 42 1.5e-43 151.96 SMART 1-92 (92) Show / Hide
Range on Protein: 808-909
Range on HMM: 1-92/92
Sequence Identity: 42% (45 aa)

EVTHIQFTSWPDH-----GVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYIL
.|.| ..|.||||     ||||  . .|...|.|..       |||||||||.|||||...|| |..       ||....| ..| ||. ||| |.||| 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIF

IHQALVE
..... |
CYRCILE

Phosphatase PTPRC.AA Subfamily.R_Nematode_3.PD 675-903 26 6.5e-39 125.3 In-house 23-258 (267) Show / Hide
Range on Protein: 675-903
Range on HMM: 23-258/267
Sequence Identity: 26% (62 aa)

NQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDgFKEPRKYIAAQGPR--------DETVDDFWRMIWEQKATVIVMVTRCEE---GNRNKCAEY
. ...|.|... .  .|| | .      ...|.|...  ...  | | .|.|          .|.. || || ..|....||.|   .. .||.||.|  
kvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseY

WPSMEEGTRAFGDVVVKINQHKRCPD-YIIQKLNIVnKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSnffsGPIVVHCSAGVGRTGTYI
..|   |..| ||  . |. ..  . ..   | . ||.    ||| ....|.....||.|. .|.| . |...      |.|||||.|..|..|   |. 
ypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk----tpvvVHCsdGisRsatla

GIDAMLEGLEAEN-KVDVYGYVVKLRRQRCLMVQVEAQYILI
  . .  .. |.|.   . .||.||   .| | ... .    
aielgyqliikskgkldllslikelrkqRagaiqtelelafv

Phosphatase PTPRC.AA Subfamily.N_Nematode_5.PD 675-910 24 1.9e-36 117.0 In-house 25-256 (258) Show / Hide
Range on Protein: 675-910
Range on HMM: 25-256/258
Sequence Identity: 24% (59 aa)

NQNKNRYVDILPYDYNRVelseINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCaEYWPSMEEGTRAF
| .|||. |.  .| .||    ...|  ..|||||.|.  .  .|.| .| |  .|. |||||. ..| | .|.... || .... ...|  ..    .|
nlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffpletgdylnl

GDVVVKINQHKRCPDY-IIQKLNIVNKKEKATgREVTHIQFTSWPDHGVPEDPHLLLKlrRRVN-AFS--NFFSGPIVVHCSAGVGRTGTYIGIDAMLEG
...... . ..  |     .. .. ..       ... ..| |... ||..   ..|  | ..  .|.. . |.||....|.||.|| ...... | |..
gkmfinnrkvevkedekkeytvevlpegcses-vfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapvvvvsdlGlgRagtflllsvaieq

LEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
......   . |.| ||. .|.  .||  ...|...|   
lnngkepnideilkkirsqRpgavesliqyasvyaavldy

Phosphatase PTPRC.AA Subfamily.N_Nematode_egg.PD 653-910 24 4.6e-32 102.9 In-house 4-255 (257) Show / Hide
Range on Protein: 653-910
Range on HMM: 4-255/257
Sequence Identity: 24% (65 aa)

AEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRC
.|. . |.. . ....| .  ...| |   .   .. ||.|   .|    ..| | ...|     ..| || |  .||.|||||....|   |||.|   
rrfeilersvdeislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsa

EEGnrNKCAEYWPSMEEGTRAF--GDVVVKINQH--KRCPDYIIQKLNIVNKKekatgREVTHIQFTSWpDHGVPEDPHLLLKLRRRVNAFsnffSGPIV
|   ..|  |||  |. .  .  | . ..  .   |  | . . ||..|  .     .|  ...   . |     | .  |.. |..       | |.||
kes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgd-----deelflehwqg-dvnylsdvysplrvlrklrnl----skpvv

VHCSAGVGRTGTYIGIDAMLEGLE--AENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEY
..  || ...| . |.  |  |      |  |   || ||..| ||.   .|..... .. .  
vqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlff

Phosphatase PTPRC.AA Subfamily.N_Fungi_PTP1.PD 677-768 37 7.1e-25 79.1 In-house 47-152 (343) Show / Hide
Range on Protein: 677-768
Range on HMM: 47-152/343
Sequence Identity: 37% (39 aa)

NKNRYVDILPYDYNRVELS-------EI-NGDAGSNYINASYIDGF-----KEPR-KYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAE
||||..||||. .||.|         .     ...||||.|.         .|  ||||.|.|  .|||||...| . | .||...|   | |..|| .|
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr

YWPSME
|.  . 
YWqegs

Phosphatase PTPRC.AA Subfamily.N_Nematode_eak.PD 668-824 26 1.9e-17 54.9 In-house 19-171 (281) Show / Hide
Range on Protein: 668-824
Range on HMM: 19-171/281
Sequence Identity: 26% (40 aa)

KEARKPFNQNKNRYVDILPYDYNRVELSEINGDAgSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSM
.....  . |.|| |.|.|.|.. |.|.    .    ||||| ..  .  |||| .  .... |  ||.|. |||.  ||..| . .|   |.|      
rvtarleavnrnrvvkivpqdrylvrltssqlnr-dGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdk

EeGTRAFGDVVVKINQHKRCPDyIIQKLNIVNKKEKATgREVTHIQFTSWPDHGVPE
  .| . |.  ..    . |..  ... .|   |  .| | ..  | .  .|     
t-evlkyGildverkeyavkrn-iletrllilrkGnet-hrvlhykvfGwtettlpk

Phosphatase PTPRC.AA Subfamily.N_Fungi_PTP1.PD 807-911 33 4.1e-16 50.3 In-house 213-342 (343) Show / Hide
Range on Protein: 807-911
Range on HMM: 213-342/343
Sequence Identity: 33% (43 aa)

REVTHIQFTSWPDHGVPEDPHLLLKLRR----------RVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEG---L----EAENKVDVY--------G
|| ..|.  |.| ..  .|. .|.               . . |  | ||.||||||||||||.. .| .|.    |    ..|.||           | 
yevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisi

YVVKLRRQRCLMVQVEAQYILIHQALVEYN
.||.||  |||   |.| |..||  |.   
ivnelrkqrismvqnldqfifiYeallfyf

Phosphatase PTPRC.AA Family.DSP.PD 742-881 16 2e-09 28.7 In-house 132-220 (387) Show / Hide
Range on Protein: 742-881
Range on HMM: 132-220/387
Sequence Identity: 16% (24 aa)

KATVIVMVTrceegnrnkcaeywpsmeegtrafgdvvvkinqhkrcpdyiiqklniV------NkkekatGREVTHIQFtSWPDHGVPEDPHLllkLRRR
. |.|| .|                                                      .        ....... ...||..|   .|. . .. 
gvtkivnlt-----------------------------------------------ddkpqftk------elgikylri-pidDhnapplenl---feka

VNaFSNF---FSGPIVVHCSAGVGRTGTYIGIDAMLE-GLEAEnkvDVYG
| .     .| ..||| ||.||.|| | .  |   ||..|   . .    
id-fieegndskgvVlVHCkaGkgRsgtliiaYlmksegltle---eald

Phosphatase PTPRC.AA Subfamily.PTPDC1.PD 800-903 24 2.2e-07 21.9 In-house 126-220 (229) Show / Hide
Range on Protein: 800-903
Range on HMM: 126-220/229
Sequence Identity: 24% (25 aa)

KKEKATGREVTHIQFtSWPDHGVPEDpHLLLKLRrRVNAFSNfFSGPIVVHCSAGVGRTGTYIGIDAMLegleaENKVDVYGYVVKLRRQRCLMVQVEAQ
..|.   ..... .| ...|.||.   . .| .  .| .|.    | | ||| || ||||  |    .       ....    . ..| .|   .|   |
dpeelmrqgiyfynf-glkDygvasl-eriLdiv-kvvdfal-eegkiavHCHAGlGRtGvliacylvy-----akrltaeeaiklvrskrpksiqtreq

YILI
  |.
velv

Phosphatase PTPRC.AA Subfamily.CDC14.PD 841-868 51 1.2e-06 19.7 In-house 195-222 (258) Show / Hide
Range on Protein: 841-868
Range on HMM: 195-222/258
Sequence Identity: 51% (14 aa)

NFFSGPIVVHCSAGVGRTGTYIGIDAML
.  .| |.||| ||.||||| ||   . 
ekaeGaiavhCkaGLGrtgtligcylik

Phosphatase PTPRC.AA Subfamily.RC.PD 941-1228 76 5e-178 581.8 In-house 1-288 (288) Show / Hide
Range on Protein: 941-1228
Range on HMM: 1-288/288
Sequence Identity: 76% (220 aa)

PLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKET
.||||||||||.||.||..|...||||||||.|.|.|||||||.||||||||||||||||||||||.||||.|||||||||.||.|||..||||||||||
lleaefqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplket

IGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQ
..|||.|||.|||||||||||||.||.|.||.||.|||..|||.|||||||||||.|.||..||...||||||.|.|.|||.|||||||.|||||...||
vddfwrmiferkvkvivmltelkeGdrekcaeyweeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliq

VVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYP
|||||||||.|||..|..||||||.|||||||.||||.|||.||||.|.||.||.|||||.||||||.|||..|||..||||...||.
vvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvetyq

Phosphatase PTPRC.AA PTPc 941-1228 32 3.6e-117 396.49 SMART 1-308 (308) Show / Hide
Range on Protein: 941-1228
Range on HMM: 1-308/308
Sequence Identity: 32% (105 aa)

PLEAEFQRLPSYRSWR---------TQHIGNQEENK--SKNRNS-NVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPE
 ...||.||.....|.         .  ... .||.  .||| . ....||..|| ||.. ..|               ...|.| ||||..|..||.| 
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGES---------------HCYEGSDYINANYIDGYWRPK

VMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHG--------DQEICAQYWGEGKQTYGDIEVDLKDTDKSS-TYTLRVFELRHSKR--------KD
 .|..||||..|| |||.|..| |...||||...  .        ..| |.||| . ..|||.|.| .|...| .  ||.|.||... ..        ..
RYICTQGPLPHTIEDFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDEPMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSE

SRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQK----------NSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKA
.|||..|.||||   . |  |. ....|..|... ...          || .  ......| ..|| .|  .|| |||.  .... |.   |||||.|| 
TRTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNS-KYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKM

LRKARPGMVSTFEQYQFLYDVIASTYP
.|. ||||| |.|||.|.|..|.  . 
MRNQRPGMVQTEEQYIFCYRCILEYIK

Phosphatase PTPRC.AA Y_phosphatase 966-1225 35 1e-104 358.98 Pfam 1-243 (243) Show / Hide
Range on Protein: 966-1225
Range on HMM: 1-243/243
Sequence Identity: 35% (96 aa)

NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMS-YWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH
||.||| .....||..|| |...                   ...|.| ||||..|.. ||.|  .|..|||...||.|||.|..| |...||||...  
NKEKNRYKDIPCYDHTRVKLQPI-------------------PGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCME

GDQ-EI-CAQYWGE----GKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKR--KDSRTVYQYQYTNWSVEQLPAE-PKELISMIQVVKQKLPQKNSSEGN
. . |  |.||| .    ...||||..| ...... . ||.|.||... ..  ...|||..|.||||   . |   || ....|. |... |        
MGRDEKTCHQYWPDNKEGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP--------

KHHKST--PLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIAS
 .. .   | ..|| .|.  || |||.  .... |.|..|||||.|| .|. ||||| |.|||.|.|..|. 
-NPDHGCPPIVVHCSAGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase PTPRC.AA Subfamily.RA.PD 942-1225 40 3.9e-68 221.1 In-house 2-263 (266) Show / Hide
Range on Protein: 942-1225
Range on HMM: 2-263/266
Sequence Identity: 40% (117 aa)

LEAEFQRLPSYRSW-RTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHelemsKesehDSDESSDddsdseepskYINASFIMSYWKPEVMIAAQGPLKET
|| ||..|.| .    . ...|.|||| |||  ...|||..|| | .     |    .  |.||          |||||||  | . . .||||||..||
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsv-----k----eGeeesd----------yinasfidGyrekdkfiaaqGpkeet

IGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWG-EGKQTYGDIEVDLKDTDKSSTYTLRVFELR----HSKRKDSRTVYQYQYTNWSVEQLPAEPKEL
. |||.||...| . ||||||||  ..| |||||  ||  |||.| | .||.  . .||.| | ..    ....|.|| | |..|.|    .|||.| ..
vedfwrmiweqksativmltelkerkeekcaqywpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGm

ISMIQVVKQKLPQKnsseGNkHhkstPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIAS
.... ||.. .|.    .| |    |. .||  |  .|| |..| ..||  ..|...|.|..|| ||. || ||| |||.|.| |.    
lkllkkvkklqqqs----an-h----pivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle

Phosphatase PTPRC.AA Subfamily.R_Anemone_1.PD 943-1224 34 5.7e-68 220.8 In-house 3-254 (258) Show / Hide
Range on Protein: 943-1224
Range on HMM: 3-254/258
Sequence Identity: 34% (96 aa)

EAEFQRLPSYRSwRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHElemskesehDSDESSDddsdseepskYINASFIMSYWKPEVMIAAQGPLKETIG
.|||||| . ..  ........|||.||| ......|  || |...         ..||.||          |||||..  .| .  ||.|.||.||..|
aaefqrlkeike-eekevarkaenkkknryadivaldhsRvvLekl---------sndeesd----------Yinasylrasdktrafiatqapleetve

DFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVV
||.|..| |. ||||||.|. |... | ||| .....||...| |. ... . |..| . | ..|....|.|.||..|.|.    | . . .... . |.
dFWrmvwqekigviVmLtnliegekkkchqYwPdstekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkv

KQKlpqknssegnKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIA
..          ......|...|| .|   ||.|...  .|| | .|.|||||..|||.|. || || | ||| |.. ..  
qks----------slagarpvvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavl

Phosphatase PTPRC.AA Subfamily.R_Ecdysozoa.PD 942-1225 36 2e-67 218.6 In-house 2-266 (269) Show / Hide
Range on Protein: 942-1225
Range on HMM: 2-266/269
Sequence Identity: 36% (104 aa)

LEAEFQRLPSY-RSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHeLEMskesehdsdessDDDsdseepSKYINASFIMSYWKPEVMIAAQGPLKET
|| |...|..   . .. ......||. |||  .....| .|| ||. ...            ..|      |.||||||| .| . .  ||||.|...|
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkk-ing------------ked------sdyinasfikgykekkkfiaaqdPveat

IGDFWQMIFQRKVKVIVMLTELKHGDQEiCAQYWG-EGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSK---RKDSRTVYQYQYTNWS-VEQLPAEPKEL
|||||.|| ...|..||||..|.  ... ||.||  | .. |||| |.| ...| | |. | .... |    .||| | ||.||.|    . |  .. |.
igDfWrmiaeqevtlivmlsnlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargl

ISMIQVVKQkLPQKNSSEGNKhhksTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIAS
 .|. |.. |...|.  | .    .|...||. |....||| ||  ||.  ..|. ||||..|| ||. |. .|  .|||.|||  .|  
lklieqvre-lyklnklsgsr----sPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad

Phosphatase PTPRC.AA Subfamily.R_Anemone_2.PD 942-1224 35 1.6e-66 216.0 In-house 2-258 (262) Show / Hide
Range on Protein: 942-1224
Range on HMM: 2-258/262
Sequence Identity: 35% (99 aa)

LEAEFQRL-PSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKheleMSkESEHDSDessdddsdseepskYINASFIMSYWKPEVMIAAQGPLKET
|..|..|| .| ..  | .  ... || ||| .|...||  || |.    |  |.|..||              ||||..|| . .  ||.|.|| ||| 
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklq----ml-egeegsd--------------yinanyidGyrrkkayiatqaPlpet

IGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYW-GEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMI
|||.|..... .||||||...   .  ...|| ..| ..||.. |.||.. ..|.|.|| |...... ...|.| |..||.|. | .|... .|..... 
iedfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlv

QVVKQKlpqknssegNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIA
|..          ..... .|...||  |  .||.|.|.  ||| ..|..||.||.|| ||. |. || | .||.|.|||.    
rqveka---------qqesgagpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvll

Phosphatase PTPRC.AA Subfamily.R_Sponge_2.PD 958-1225 34 3.9e-64 208.1 In-house 17-259 (262) Show / Hide
Range on Protein: 958-1225
Range on HMM: 17-259/262
Sequence Identity: 34% (94 aa)

QHIGNQEENKSKNRNSNVIPYDYNRVPLKhelemskesE---HDSDessdddsdseepskYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVK
.|....||..||| ....||| .|| |.         .   .|||              ||||||. .| ...  ||.|||||||..||| |..  ||. 
lsiaklkenvgKnRfkeilpydmsRvrLr---------tdgskdsD--------------YinAsfvdgykrrkayiatqgPlketveDfWRmvweykvs

VIVMLTELKHGDQEICAQYWGEG---KQTYGDIEVDLKDTDKSSTYTLRVFELRHSKR-KDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKlpqkN
|||||.|.  ..| ||.|| |    ...||...| ||.. |.. |..| ..| ..|  .....| |.....|. .. |..   |...|. |...    . 
tivmltnleengkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlra----q

SSEGNKhhkstPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIAS
 .|||     .. ..|.||  .|| |.||  .||  ..||..|.|.|.| ||  |.|.|.. .||.|..|.... 
kksgnk-----aitvvCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalle

Phosphatase PTPRC.AA Subfamily.RG.PD 942-1225 32 1.8e-62 202.6 In-house 2-261 (264) Show / Hide
Range on Protein: 942-1225
Range on HMM: 2-261/264
Sequence Identity: 32% (94 aa)

LEAEFQRLPSYRSWR-TQHIGNQEENKSKNRNSNVIPYDYNRVPLKHElemskeSEHDSDessdDdsdseepskYINASFIMSYWKPEVMIAAQGPLKET
||..|. . . ..   . .  ..|||| |||..|.....  ||.|.        ...|..    |         |||||.|. | . .  |..|||||||
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklspl------pgkdgk----D---------YinAsyidGyrrskeyivtqgplket

IGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGE--GKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRT--VYQYQYTNWSVEQLPAEPkeLI
| |||.||.......|||||.|..  .. ...|| .  .  ......| |....| |.||.| | |.. | .....  |.||.||.|   . |     | 
iedFWrmiWehnaqiivmltdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPest--lf

SMIQVVKQklpqknssEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIAS
 .|.|.|.        |  ..... |...|.. |. ..|...||  ||.  |.|| |...||.| .|. |||.| ||||.|.||.. . 
vlifvkke--------eaankeeaGPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydalle

Phosphatase PTPRC.AA Subfamily.RK.PD 956-1223 33 2.9e-60 195.1 In-house 19-262 (267) Show / Hide
Range on Protein: 956-1223
Range on HMM: 19-262/267
Sequence Identity: 33% (90 aa)

RTQHIGNQEENKSKNRNSNVIPYDYNRVPLKhelemskesehdsdeSSDDDSdseepSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKV
|. ...|..|||  ....||  .| |.               | |.||     |.||||..| || .|.  |..||||.||. |||..... .   ||||
edcdiakkdrnreknrsmdilaydrslvfli---------------svdgds-----sdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencas

IVMLTELKHGD-QEICAQYWGEGKQT-YGDIEVDLKDTDKSSTYTLRVFELRH--SKRKDSRTVYQYQYTNWSVE-QLPAEPKELISMIQVVKQKLPQkn
|||.    .  | .|| |  .. ||||.| | ...  . .  |.| ...   . .. |.| |.|...|.   . | . .|...|. ||.. ..       
ivmlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee--

ssegnkhHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVI
  ..  ....|| .|. ..|.|.|.  .|| .|.|.|||.|..||.||. .. || | |||.|.||||     
-------eeeGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvi

Phosphatase PTPRC.AA Subfamily.N5_RR.PD 942-1224 31 9.8e-59 190.3 In-house 2-261 (265) Show / Hide
Range on Protein: 942-1224
Range on HMM: 2-261/265
Sequence Identity: 31% (90 aa)

LEAEFQRLPSYRSWRTQHIGNqeeNKSKNRNSNVIPYDYNRVPLKHELEMskesehdsdessdddsdsEEPSKYINASFIMSYW-KPEVMIAAQGPLKET
||.||  ||.  | . ...     ...||| ....| .  || |..|                     .| |.|||| .|  |  . ...|.|||| .||
lekeflelPlnfsqeelevfg---sqtknryktilPnensrvllesesse------------------dedssyinanyikGydeeskayvatqGPlpnt

IGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQT-----YGDIEVDLKDTDKSSTYTLRVFELRHSKRkDSRTVYQYQYTNWSVEQLPAEPKEL
 |||.||.|..|.||||||.||  ... ||.|. . ...     |||.|.  ... .   |..| . |....|  .|.|. | ||.|  .. | ....|.
iadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintl

ISMIQVVkqklpqkNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIA
.... |       ..|. ....| .|...||  |  .||.| | .. .   . |.|||....|  ||  | ||| | |||.... ... 
ldlvlev-------eesreeenaklaPvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc

Phosphatase PTPRC.AA Subfamily.RB.PD 945-1225 31 5.1e-57 184.7 In-house 5-258 (261) Show / Hide
Range on Protein: 945-1225
Range on HMM: 5-258/261
Sequence Identity: 31% (89 aa)

EFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHeleMskesehdS-----DessdddsdseepskYINASFIMSYWKPEVMIAAQGPLKE
|...| .  . ....  ....|. ||| .|..|||..|| |..   .       .     |              ||||..|  | .|   ||.||||.|
eyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaa---l-------kdesdtd--------------yinanyipgynspreyiatqGPlpe

TIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK--QTYGDIEVDLKDTDKSSTYTLRVFELRHskRKDSRTVYQYQYTNWSVEQLPAEPKELIS
|. |||.|....|...|||||.|  . .| | .|| . .  ..||||.|.|. ... .....| |....  .|..|.| ||..||.    | ..| |...
tvddfWrmvwekkssiivmltqlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlld

MIQVVKQKLPQKnssegnkhHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIAS
.. |.... .|         ...|...||  |   ||.| || .||.. |....||.| ||  ||. |  .| |.|| |.......  
fvrtvreaiekk--------askkPivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclld

Phosphatase PTPRC.AA Subfamily.N12.PD 957-1225 31 1.3e-56 183.1 In-house 23-267 (270) Show / Hide
Range on Protein: 957-1225
Range on HMM: 23-267/270
Sequence Identity: 31% (85 aa)

TQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSkesehdsdessdddsdseePSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVI
... |..|||. |||  ...|||..|| |... |                      | ||||.||    ..   ||||||| .|. |||.||.. .|...
steagekeenvkknrykDilPydksrvelskieeee-------------------gsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveiv

VMLTELKHGDQEICAQYWGEG---KQTYGDIEVDLKDTDKSS-TYTLRVFELRHSkrKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPqknss
||. ..   ..  |..|| |    . ..|..||.|.. .. .  ...| ......  |.||.|||..||.|   . |...|.|...|. |..        
vmaCrevelgkkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqe-----

egnkhHKSTPLLIHCRDGSQQTGIFCAL---LNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIAS
     ....||..||  |  .||. .|.    .||..  ..| .|.|..|  ||| |. .| | |||...|.|.  
-----sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae

Phosphatase PTPRC.AA Subfamily.N_Choan_1.PD 945-1224 30 3.1e-53 172.3 In-house 5-258 (262) Show / Hide
Range on Protein: 945-1224
Range on HMM: 5-258/262
Sequence Identity: 30% (86 aa)

EFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSkesehdsdessdddsdseePSKYINASFIMSYWKPEVMIAAQGPLKETIGDF
|.. | .     | .  ...||. ||| ||.. ||  || .... | .                    . ||||.|. .| ...||.|||. ... .|||
eyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenk-------------------ntDyinanfvpgykgekeyiatqgPvPaslvsf

WQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK--QTYGDIEVDLKDTDKSSTYTLRVFELrHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVV
|....||..|||.|.  ....  | .|| ...   ..||. |  . . ...||  |.|.| . .  ..|.| | .||.|     ||..|||..  . |..
WqmvweqkvsaivmvtreieagklkChryWPdenselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkav

KQKLPQKNSsegnkhhksTPLLIHCRDGSQQTGIFCALLNLLESAETEE-VVDIFQVVKALRKARPGMVSTFEQYQFLYDVIA
   .|.          .||.|||  |  .|| . ||  |....|... ..|..||. |||.|  || |  ||.|.| ..    
lkatkkktk---------aplvihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavl

Phosphatase PTPRC.AA Subfamily.N23.PD 946-1223 26 4.5e-51 165.3 In-house 44-345 (350) Show / Hide
Range on Protein: 946-1223
Range on HMM: 44-345/350
Sequence Identity: 26% (82 aa)

FQRLPSY----RSWRTQHIGNQEENKSKNR--NSNVIPY-----DYNRVPLKHELEMS--------KESEHDSDESSDD-DSDSEEPSKYINASFIMSY-
.. |..|    .. . | |   . . .|||  | ...||     . . ||  . |.          ..| ||.     .  .. .. . ||||... .  
wseledyqgqeaiaadqsiasakrmsnknrqfnpdllpyhlqpttitavpqprhlqtegsGqqqgtpdsrhdpnrvklqqstqpgqqddyinatylkelt

-WKPEvMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK---QTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQY
   |. .||.|||...|..|||.|.......||||||. . |..  |.||| . .   ...||..| ||.. .|...  ||..|.|.. .  |.| . ..
pmsPp-fiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrssegwiervlhlqhndvstvrlvchlht

TNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKhHKSTPLLIHCRDGSQQTGIFCALLNLL-ESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFL
|.||.  .|. |..|. ....|.. . |.. .| .      |...||  |.. ||.|| .   . |  . . ...| .||. ||. |  ||.. .....|
ttWseiGvPksPedllaflgevetayaqqrkteteg-eggkPiilhCsaGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkkl

YDVI
|...
yeav

Phosphatase PTPRC.AA Subfamily.N14.PD 944-1224 31 3.1e-50 162.3 In-house 4-271 (275) Show / Hide
Range on Protein: 944-1224
Range on HMM: 4-271/275
Sequence Identity: 31% (90 aa)

AEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKheleMSKESEHDsdessdddsdseepskYINASFIMSYW--KPEVMIAAQGPLKETI
.|..|.|  |   . . .. .||..|||  .|.||. ||| |.     .||....                ||||| |      |    |.|||||..|.
teyeripkkredallstaklpenaeknrfkdvlPyednrvels----ptkenstg----------------yinassikvsvggkersyivaqgPleltv

GDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEG-----KQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELI
 |||||.....|..|||||| . . .| . .|. .      . ..|  .|  | ...|.... . ..|.|   |. |||.|||.|. ...| ..|...| 
qdfwqmvweqgvqlivmlteeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgfl

SMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIA
.. |.    . ||.  . .... |.|.|| .|  .||.      |... |..|..|| .|.. ||| |  .|.|. ||.|.|.|.   
sfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvli

Phosphatase PTPRC.AA Subfamily.N9.PD 958-1223 30 4.3e-50 162.1 In-house 18-270 (275) Show / Hide
Range on Protein: 958-1223
Range on HMM: 18-270/275
Sequence Identity: 30% (83 aa)

QHIGNQEENKSKNRNSNVIPYDYNRVPLKHElemskesehdsdessdddsDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIV
.  ..  | .||| ..|. ||  || |...                   | .| | ||||.|.  | ... .||.|||||.|. |||.|.....| ||||
flasklranleknrytdvlcydetrvklakl-------------------dedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlviv

MLTELKHGDQEICAQYWGE---GKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEG
 | .    .  |.||| .    .. .||..|   ...... |. ||.|....| ..||.|  .|.. |     | . ..|. ....|..|  .  .. | 
mttrvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelg

---NKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVI
  . | .  |...||  |  .|| |..|   |.  |....||....|| ||. |  .. | |||.| |  . 
deskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylav

Phosphatase PTPRC.AA Subfamily.N3.PD 1011-1227 29 1.9e-46 149.8 In-house 48-260 (261) Show / Hide
Range on Protein: 1011-1227
Range on HMM: 48-260/261
Sequence Identity: 29% (65 aa)

EPSKYINASFIMSYWKP-EV---MIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEG--KQTYGDIEVDLKDTDKSSTYTLRVFEL
... ||||...       ..    ||.||||..|  |||||....|...|||||.|    .  | ||| |   ....|...| .. .|....| || . |
setdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqyWPetedelefgefsvrcekedetksyvlrelvl

RHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLpqknssegnkHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRK
.... |..|...| ||..|. ...| .......... |...           . |..|...||  |  .||.. .|   |   |..| | . ..|. .| 
kdketkeerkilqlqylaWpdhgvPddsadflefvervrklr----------sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrd

ARPGMVSTFEQYQFLYDVIASTY
 |  .| | .||.|. . |   |
qramlvqtvsqykfvCeailkay

Phosphatase PTPRC.AA Subfamily.N_Choan_2.PD 946-1224 26 2.2e-46 149.6 In-house 2-262 (266) Show / Hide
Range on Protein: 946-1224
Range on HMM: 2-262/266
Sequence Identity: 26% (75 aa)

FQRLPSYRSwRTQHIGNQEENKSKNRNSNVIPYDYNRVPLkhelemskesehdsdessdDDSDSEEPSKYINASFIMS-YWKPEVMIAAQGPLKETIGDF
|.||.  ..  ...| .   ||  ||  ...|    || |                   .. .... ..|||| ..     ...|||.|||. |. .||.
fkrldkqev-seeaiPeyarnkrlnRyndiLPsPatRvrl-------------------eeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksf

WQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQ-----TYGDIEVDLKDTDKSSTYTLRVFELRHskRKDSRTVYQYQYTNWSVEQLPAEPKELISMI
||...||. |||.|.|.  ... |..|| . ..     ..|.|.|    . |.. | |.  .|..  ....|..  ..|..|  .  | |. . .|  |.
wrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstd

QVVKQKLPQKNSSegNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIA
.|     ....  .. .|..|||.|| .|   ||.. |.   ..  |... ||. .....||| |. .|.. |||..|| ...  
qllkmlravrrvr--keldkaePllvHcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavv

Phosphatase PTPRC.AA Subfamily.RN.PD 942-1224 34 8.4e-46 147.8 In-house 2-260 (264) Show / Hide
Range on Protein: 942-1224
Range on HMM: 2-260/264
Sequence Identity: 34% (97 aa)

LEAEFQRLPSYRSW-RTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHElemskesehdsdeSsdddsdSEEPSKYINASFIMSY-WKPEVMIAAQGPLKE
||.|.. | .|..  .|......|.| .|||...|.||| .|| ||.|             .      |.| |.|||||.|.    .  . ||.|||| .
lekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkee-------------a------saeksdyinasaildhdprapayiatqgplss

TIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWG-EGKQTYGDIEVDLKDTD-KSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELIS
|| |||||.... | |||.||.|.. . . |..||  ||...|.  ||.|      .  | .| | |.  . ...||| |. .|  |. ||..| |. . 
tiadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasakslle

MIQVVKQklpqknSSEGnkhhKSTPLLIHCRDGSQQTGIFCALLNLLES-AETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIA
. | .      |  |    .|.|...|| ||. .||.....  .||  .     .||   .. ||  |||.| |.|..| . ..|   
frrkvnk------syrG----rscpivvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltava

Phosphatase PTPRC.AA Subfamily.N13.PD 1012-1223 30 3.6e-40 129.5 In-house 48-254 (259) Show / Hide
Range on Protein: 1012-1223
Range on HMM: 48-254/259
Sequence Identity: 30% (65 aa)

PSKYINASFIMSYWKPE--VMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQ----TYGDIEVDLKDTDKSSTYTLRVFELR
. |||||.|      .  ..||.|||| ||. |||||....|..||.|.|  | ...  | .|| | |.     .. .||.| .. | .....| .....
eggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavk

HSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQkLpqknssegnkHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKA
|. ..|| | . ....|   . |....||. ... |.. |          .....|...||  |  ..|.. ..  .|.| .. .|. ..|. ||. | |
dsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrl-l----------qtdagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreq

RPGMVSTFEQYQFLYDVI
.| | .|| | | .|   
rqgvvqtkdqyifvykai

Phosphatase PTPRC.AA PTPc_motif 1114-1225 34 1.1e-35 125.83 SMART 1-92 (92) Show / Hide
Range on Protein: 1114-1225
Range on HMM: 1-92/92
Sequence Identity: 34% (40 aa)

TVYQYQYTNWSVE-----QLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPG
||..|.||||         .|   . ....|. |..                 |...|| .|   || |||.  ....      |||||.||..|| |||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-----------------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPG

MVSTFEQYQFLYDVIAS
|| |.|||.|.|..|..
MVQTEEQYIFCYRCILE

Phosphatase PTPRC.AA Subfamily.N1.PD 1012-1223 27 2.9e-35 113.4 In-house 51-263 (268) Show / Hide
Range on Protein: 1012-1223
Range on HMM: 51-263/268
Sequence Identity: 27% (59 aa)

PSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQT----YGD--IEVDLKDTDKSSTYTLRVFELR
.|||||..         | .|||| .|.. ||||..... | ..|| ..   .|  ||||| .....    . .  ..| |  ....| ...| .||.  
dvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqeeeeaellleetklkvkliseerksyflvrlleLe

HSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKlpqknsseGNKHHKSTPLLIHCRDGSQQTGIFCALL---NLLESAETEEVVDIFQVVKAL
. ...|......||.|.   .|  |. ...... |..         |   .. .|. |||  | ...| .. .     ..|.  . ||| .|. .||| |
dletqetreilhfhyttwpdfgvpespaafLkfLfkvres--------gsLssdvgpavihCsagigrsgtlslvdtclveiektgdlnavdikkvLlel

RKARPGMVSTFEQYQFLYDVI
 |.. | .| .| |  |    
RkyRvGLiqtpdqLrFsyiai

Phosphatase PTPRC.AA Subfamily.N_Nematode_5.PD 959-1224 22 4.7e-35 112.4 In-house 18-254 (258) Show / Hide
Range on Protein: 959-1224
Range on HMM: 18-254/258
Sequence Identity: 22% (60 aa)

HIGNQEENKSKNRNSNVIPYDYNRVplkhelemskesehdsdessdddSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVM
.  . |.|..|||. .|  .| .||                       . ..|...||||| |.     . .| .| ||..|. |||.|..| |.. .|.
tckafeknlkknrskdvkilDetrV-----------------------kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvl

LTELKHGDQEICaQYWG---EGKQTYGDIEVDLKDTDKSSTY-TLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEPKELIS-MIQVVKQKLPQKNsse
|.| .. ..  . ...    .  ...|.. .  . ......  .  ..|.   .  .|  .  |..|.|  .. |.. |..|  .|. | .|  .||   
lvedeelketav-sffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgkn---

gnkhhksTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIA
       .|.....  |. ..| | .|.   |. .... ..| ...|..|. |||.| .. || ..| ...
-------apvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavl

Phosphatase PTPRC.AA Subfamily.N_Nematode_4.PD 1013-1225 25 1.7e-29 94.4 In-house 52-261 (264) Show / Hide
Range on Protein: 1013-1225
Range on HMM: 52-261/264
Sequence Identity: 25% (54 aa)

SKYINASFIMSYwKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQT---YGDIEVDLKDTDKS--STYTLRVFELRHS
|| ||...        |..|||||||. ||| |... |..|.||| .|  ...| ||.|. | ...   .|. .. | ...   .   |. ...   . .
ndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkfGkyritlvekkeeviadvilnslkvtnt

K-RKDSRT---VYQYQYTNWSVEQLpaEPKELISMIQVVKQKLpqknssegnKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALR
||. .   |... . .|  .|.   |.. ...|.. |            |..|..|. .|||  .|  .  .            ... ..|. ||. | .
ekkkdapseplvvkhvqvdwwrdqv--aPldaapviklykavk---------kkkkekPivvhcsaGvGrtatlvGidyatirirenseievldivrelr

KARPGMVSTFEQYQFLYDVIAS
 | .  |. ||. |..      
amrlkavqshlqflfllvvlie

Phosphatase PTPRC.AA Subfamily.R_Nematode_3.PD 1013-1223 24 3e-28 90.3 In-house 51-262 (267) Show / Hide
Range on Protein: 1013-1223
Range on HMM: 51-262/267
Sequence Identity: 24% (56 aa)

SKYINASFIMSYwKPEVMIAAQGPL--------KETIGDFWQMIFQRKVKVIVMLTELKH---GDQEICAQYWGE---GKQTYGDIEVDL--KDTDKSST
...|.|....   .   .| .|.|.        |.||  ||.|| | ||...||| . .    ...| |..|. |   |.......|    .....|   
ddfihAnvvecp-nglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYypekvdgelkfegvsvkctdikkelsed

YTLRVFELrHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQklpqknssegnkhHKsTPLLIHCRDGSQQTGIFCALLNLLES-AETEEVVDI
  | ... . . |.  ||  ..|. |. .. | ||||....|..|..              |||...|| ||  ... . |     .  ..... .|. .
vekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfvek-------------sk-tpvvVHCsdGisRsatlaaielgyqliikskgkldl

FQVVKALRKARPGMVSTFEQYQFLYDVI
..|.||| |.| ..| ... |.  .|  
lslikelrkqRagaiqtelelafvilgi

Phosphatase PTPRC.AA Subfamily.R_Nematode_2.PD 1016-1220 26 2.6e-27 87.1 In-house 57-253 (261) Show / Hide
Range on Protein: 1016-1220
Range on HMM: 57-253/261
Sequence Identity: 26% (56 aa)

INASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQ---TYGDIEVDLKDTDKSST--YTLRVFELRHSKR-
| | ..    .|.  ||.||||..|  ||| |. | ||  ||||..     .|.|..|.   ..   . | ...  ....|.   . |...   |.   .
ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgk

KDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQklpqknsSegnkhhkSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGM
.|||  |||..|. ...|   .||  ....||.       |         |...||  |  .|. | .   | .  |... . . . .| ||. |.  . 
fatrtvthyqyeeWpdrgvPkshaelfeLlelvkk-------s-------ekPivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkg

VSTFEQYQFLY
| .|. .|   
iqtesqlywlt

Phosphatase PTPRC.AA Subfamily.N20.PD 1014-1223 30 1.2e-26 85.3 In-house 50-252 (257) Show / Hide
Range on Protein: 1014-1223
Range on HMM: 50-252/257
Sequence Identity: 30% (64 aa)

KYINASFIMSY--WKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGKQT---YGDIEVDLKDTDKSSTYTLRVFELRHSK
|||||.|      .  . ||.||||  || |||||... . .|| |.|    |    | .||    .       . | |.. .    . .|.|..     
dyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkkplelkhfrvflenyqilqyfiirmfqvveks

RKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKqklpqknssegnKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPG
  |..| | |.|.|     ||    .|  |.  .            | | . |...||  |  .||.| ..  .. .   ...|...|  .|. | ||| 
tgtshsvkqlqftkwpdhgtpasadsfikyiryar------------kshltgpmvvhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsg

MVSTFEQYQFLYDVI
| |||.| ||..   
mvqtkeqyhfcydiv

Phosphatase PTPRC.AA Subfamily.N_Fungi_PTP1.PD 966-1096 35 1.1e-25 81.8 In-house 45-168 (343) Show / Hide
Range on Protein: 966-1096
Range on HMM: 45-168/343
Sequence Identity: 35% (47 aa)

NKSKNRNSNVIPYDYNRVPLKHELEMSKESEHdSDESSDddsdseepskYINASFIMSY-----WKPEV-MIAAQGPLKETIGDFWQMIFQRKVKVIVML
.||| .|..||. .|| ||. |. |.  .| | ...|          ||||...         .|.   ||.|.||..|.||...|.. |||||..||..
lfaknrYknilPYehsrvkLkkslkssdakkh-slstnD----------YinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsl

TELKHGDQEICAQYWGEGkqTYGDIEVDLKDTDKSST
   . | | .|| ||  .| || | |... .. .   
tsdvelnlekcyrYWqeg--sydditvklaskwenim

Phosphatase PTPRC.AA Subfamily.N_Nematode_1.PD 1010-1224 26 6e-25 79.4 In-house 49-261 (265) Show / Hide
Range on Protein: 1010-1224
Range on HMM: 49-261/265
Sequence Identity: 26% (60 aa)

EEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK---QTYGD----IEV----DLKDTDkSSTYT
||.|| | ..    .|  .| ||.||..|| ||| |..| ||. |||| .|    .  ||.|.   .   ... .    ||    . | .. ..  ...|
plpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkle-edeev

LRVFELRHSK-RKDSRTVYQYQYTNWSVEQLPAEPKELIsmiqvvkqklpqkNSSEgNKHHKSTPLLIHCRDGSQQTGIFCALLNLLES-AETEEVVDIF
 .|. .   ...|.| .||.|.|     |.     .             .  | . ... .|...||  |  .||   |.  .|.  .| ... |. ..|
ikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaal-------------elle-avrgskgPivvhCsaGiGrtGtivaieyildkllegkqiedme

QVVKALRKARPGMVSTFEQYQFLYDVIA
|..|. |   . |  || |.. |.    
klvkkireqrnysiqtdaqylfvhrvll

Phosphatase PTPRC.AA Subfamily.N_Nematode_6.PD 1011-1220 26 4.3e-23 73.5 In-house 46-245 (253) Show / Hide
Range on Protein: 1011-1220
Range on HMM: 46-245/253
Sequence Identity: 26% (58 aa)

EPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEG---KQTYGD----IEVDLKDTDKSSTYTLrvfe
..  || |... .  ||. .| .|.||..|| .||.||.   |. |||| ||    .| .|.|  .    .. ...    |... || ||  . .|    
dedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrsl----

LRHSKRKD--SrTVYQYQYTNWSVEQLPAEPKELISMIQVVKQklpqknssegnkHHKstPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKA
.| .|  |  .  |  ... ||    .| . .  . ...|||.            ..|  |...||  |  .|| .  .| .||.  . .  .. ...  
krivkagdeev-ivkhihWanWPdhGvPdsflsalrllsvvkk------------dkk--PivvhCsaGvGrtGtlaliliilealrlpdfqgvkdllvk

LRKARPGMVSTFEQYQFLY
||. |   | |. || . .
lreerfravqtevqylyal

Phosphatase PTPRC.AA Subfamily.N_Nematode_egg.PD 945-1224 22 1.2e-19 62.2 In-house 5-253 (257) Show / Hide
Range on Protein: 945-1224
Range on HMM: 5-253/257
Sequence Identity: 22% (64 aa)

EFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKEsehdsdessdddsdseepsKYINASFIMSYWKPEVMIAAQGPLKETIGDF
.|..|       . .   ..... | |.  |   .. || |. .  .  .                    .| | ... .| || |||.|  |||.|.||
rfeilersvdeislttaasdnylekarskrvhckessrvklelrrGqyld-------------------dfihanrvkGkpllnefilaqaplkntvedf

WQMIFQRKVKVIVMLTELKHGdqEICAQYWGEGKQ----T-YGDIEVDLKDTDKSSTYTLRVFELRHSKRKD-SRTVYQYQytnWSVEQLpaepKELISM
 ||. |||||  |.   | |  ||   ..    |  | ....  . |. .   .|| .|.    .|  . .  .|   . |..|     .. | ..|...
wrmvfqekvqyivmltsakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwq---gdvnyl----sdvysp

IQVVKQKlpqknssegnkHHKSTPLLIHCRDGSQQTGIF----CALLNLLESAETEEVvdIFQVVKALRKARPGMVSTFEQYQFLYDVIA
             . |.| .... .|  ... .|||.||    |  .  . . |. ||. |.  |..  .| |.| ...           
lrvlrkl-----------rnlskpvvvqdilGvskaatlvaieiallsllrGpitksl--vlravvflrlrrrlsvesvllylfvyrlvl

Phosphatase PTPRC.AA Subfamily.N_Fungi_PTP1.PD 1111-1223 26 8.4e-16 49.3 In-house 211-338 (343) Show / Hide
Range on Protein: 1111-1223
Range on HMM: 211-338/343
Sequence Identity: 26% (34 aa)

DSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLE-----SAETEE---------VVD-I
.  .||| |. ||    |  .|........| .. . . .. .  .  .|.|.|.||  |  .||....|  ||.     .|.|         . | |..
epyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDli

FQVVKALRKARPGMVSTFEQYQFLYDVI
.|. ||| |  || . .|. |.|. .  
siivnelrkqrismvqnldqfifiYeal

Phosphatase PTPRC.AA Subfamily.N_Nematode_eak.PD 950-1224 20 5.6e-12 37.0 In-house 10-277 (281) Show / Hide
Range on Protein: 950-1224
Range on HMM: 10-277/281
Sequence Identity: 20% (57 aa)

PSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKhelemskesehdsdessdddSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIF
|.  .... ... |.  .||  ...|.|.. | |                     |   ..  ||||| .      .| .  . .. .  ||||....| 
ddyqrllsirvtarleavnrnrvvkivpqdrylvrlt--------------------ssqlnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvl

QRKVKVIVMLTELKHGDQEICAQYWGEG--KQTYGDIEVDLKDT-DKSSTYTLRVFELRHSkrKDSRTVYQYQYTNWSVEQLPAEpKELISMIQVVKQK-
  ||.| |    . |   .|. .   .  || ..|. |.   | . .  | ..||..  |. |..  |.  .||   ...... .|.|.     |  ...
eqkspaivqlledveekleksdkyfpdktevlkyGildverkeyavkrniletrllilrkG--nethrvlhykvfGwtettlpky-edflalrkvmkevG

---L--PQKN--SSEGNKHHKSTP---LLIHCRDGSQQTGIFCA---LLNLLESAETeEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIA
.  .|  .|.... |    .| .  || ..|.|     |..|...  . ..  . ...   .. |   | .  |. |.|...          
vlllivmksallrstlkkyihtppsfapiiqsarGsaraGvfvvidllirlidnkkk-nlysvedlilkvkskrihsvlvalqhsfiyeivl

Phosphatase PTPRC.AA Subfamily.N13.PD 944-988 45 1.7e-06 19.1 In-house 4-48 (259) Show / Hide
Range on Protein: 944-988
Range on HMM: 4-48/259
Sequence Identity: 45% (20 aa)

AEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHE
||. |   ..  | ..|...|||.|||  ||.|||  ||.|. | 
eefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgde

Sequence
Name Sequence Type Origin Length Description Download
PTPRC.AA Protein None 1304 None Fasta, JSON
PTPRC.NA RNA None 3912 None Fasta, JSON
PTPRC.AA.PD2_941-1228 Protein Phosphatase Domain None 288 None Fasta, JSON
PTPRC.AA.PD1_650-912 Protein Phosphatase Domain None 263 None Fasta, JSON