• Phosphatome.Net

Gene PTPRF

PTPRF
Species: Human
Alias: PTPRF, FLJ45567, LAR, FLJ43335, FLJ45062
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RD
Protein domain

Protein domains of PTPRF.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ig PTPRF.AA I-set 33-124 35 3.7e-25 87.87 Pfam 1-92 (92) Show / Hide 
Range on Protein: 33-124
Range on HMM: 1-92/92
Sequence Identity: 35% (33 aa)

PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVS--SQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSV
|.|...| |..   |  | | ||.||.|.| ..| |.|....  |.|. . . . .  . |.|.     .|| .|.|.||||.||  ..|.| |
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDG-DGTYTLTISNVQP-DDEGKYTCVATNSFGEAECTAELTV
Ig PTPRF.AA IGc2 45-114 27 1.4e-14 55.73 SMART 1-56 (56) Show / Hide 
Range on Protein: 45-114
Range on HMM: 1-56/56
Sequence Identity: 27% (19 aa)

LSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLG
..|. ... | ||| | | |.| | |....             .. |.|.. .   |. .|.|.|.|. |
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP------------WNWTLTIKNVT-PEDSGYYTCYARNPWG
Ig PTPRF.AA I-set 135-215 36 1.7e-12 44.95 Pfam 1-83 (92) Show / Hide 
Range on Protein: 135-215
Range on HMM: 1-83/92
Sequence Identity: 36% (31 aa)

PSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSG----ALQIESSEESDQGKYECVATNSAGT
|...  |.  .|    ||.  | . |.|.|..|||||  |. |  .. |..  ..|     | |.  . .| |||.||||||.|.
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRP--DSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGE
Ig PTPRF.AA IG 39-125 16 1.3e-11 45.84 SMART 1-58 (58) Show / Hide 
Range on Protein: 39-125
Range on HMM: 1-58/58
Sequence Identity: 16% (15 aa)

PEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRD--EAIYECTATNSLGEINT--SAKLSVL
|. .|.  |. ... | ..     .|.|.                       |.| .....    ...| |.||   |..    ...|.|.
PP-VTVKEGETVTLTC-VS-----QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
Ig PTPRF.AA IGc2 147-214 30 3.1e-15 57.88 SMART 1-56 (56) Show / Hide 
Range on Protein: 147-214
Range on HMM: 1-56/56
Sequence Identity: 30% (21 aa)

EKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAG
.  ...|. | | |||||.|.|.|   |..            .. |.|.. ...| |.|.|.|.|..|
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG
Ig PTPRF.AA IG 141-226 21 4.5e-12 47.35 SMART 1-58 (58) Show / Hide 
Range on Protein: 141-226
Range on HMM: 1-58/58
Sequence Identity: 21% (19 aa)

PQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQ---GKYECVATNSAGTRYS-APANLYVR
|.  .|    |.|. | .      .|.|.                      |.| . ...|.   | | |.||  .|. .|  ...|.|.
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
Ig PTPRF.AA I-set 232-265 35 1.4e-08 31.66 Pfam 1-34 (92) Show / Hide 
Range on Protein: 232-265
Range on HMM: 1-34/92
Sequence Identity: 35% (12 aa)

PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKW
|.|...|...||. | .....| . | | | | |
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSW
Fn3 PTPRF.AA FN3 319-398 29 1.1e-16 62.64 SMART 1-69 (69) Show / Hide 
Range on Protein: 319-398
Range on HMM: 1-69/69
Sequence Identity: 29% (28 aa)

PKPPID---LVVTETTAT------SVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPF----SEYAFRVLAVNS--IGRG
| || .   |.||..|.|      ||||.|.      ...|                       | . ||.|     .|| ||| |||.   |.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Ig PTPRF.AA IG 238-316 19 3e-14 54.56 SMART 1-58 (58) Show / Hide 
Range on Protein: 238-316
Range on HMM: 1-58/58
Sequence Identity: 19% (17 aa)

PSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRS-----ANYTCVAISSLGMIEA--TAQVTVK
|. ..|..|..|.||| .      ...|.                  |.. || ..     ..|.|.|    |....  ....||.
PP-VTVKEGETVTLTC-VS-----QIWWY------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ
Ig PTPRF.AA IGc2 244-305 32 2e-06 28.79 SMART 1-56 (56) Show / Hide 
Range on Protein: 244-305
Range on HMM: 1-56/56
Sequence Identity: 32% (21 aa)

MPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVR--SANYTCVAISSLG
 .|.|| ||| | |.| | ..|    ..|        ... |...|| .  | .|||.| .. |
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-------WNWTLTIKNVTPEDSGYYTCYARNPWG
Fn3 PTPRF.AA FN3 414-497 18 2e-13 51.85 SMART 1-69 (69) Show / Hide 
Range on Protein: 414-497
Range on HMM: 1-69/69
Sequence Identity: 18% (18 aa)

SSPPRR---VQARMLSAS------TMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPG----ITYSLRVLAFTA--VGDG
 .||..   ....  ...      .. ..|.||          .|.|.                     ||  | ||     .|. || |...  .| |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----------IVGYR--------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 PTPRF.AA FN3 512-591 22 1.3e-13 52.42 SMART 1-69 (69) Show / Hide 
Range on Protein: 512-591
Range on HMM: 1-69/69
Sequence Identity: 22% (21 aa)

PAQPAD---FQAEVESDT------RIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPD----TLYRFQLAARSD--MGVG
|  | .   ....  ..|       ..|||  ||   |. |.                      ||...|||.    | |.|...|...   | |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWK-PP---IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 PTPRF.AA FN3 606-693 21 2.2e-12 48.38 SMART 1-69 (69) Show / Hide 
Range on Protein: 606-693
Range on HMM: 1-69/69
Sequence Identity: 21% (22 aa)

PSAPPQK--VMCVSMGST------TVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKW----TEYRVWVRAHTD--VG
|..||    .  .. .||      .|..|| ||        |..|.                           . ||. .    |||...|||...  .|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR-------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAG

PG
.|
EG
Fn3 PTPRF.AA FN3 709-806 20 5.1e-13 50.5 SMART 1-69 (69) Show / Hide 
Range on Protein: 709-806
Range on HMM: 1-69/69
Sequence Identity: 20% (23 aa)

SGPPRK---VEVEPLNST------AVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPE----TTYSV
 |||.    ..|.. .||       |.. || |        | ||.                                     |..||.|     |.|..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR------------------------------------YTVTGLKPGQYPWTEYEF

TVAAYTT--KGDG
.|.|..   .| |
RVRAVNGNDAGEG
Fn3 PTPRF.AA FN3 821-901 26 1.8e-11 45.32 SMART 1-69 (69) Show / Hide 
Range on Protein: 821-901
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PGRPTM---MIST-TAMN------TALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKG----TTYIFRLAAKNR--AGLG
|| |.       | .  .      .. |.| ||       .|||                      .|||||. |    |.| ||..|.|.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 PTPRF.AA FN3 916-997 26 1e-15 59.44 SMART 1-69 (69) Show / Hide 
Range on Protein: 916-997
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

SGFPQN---LHVTGLTTS------TTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTDTRFTLTGLKPD----TTYDIKVRAWTS--KGSG
 | |.|   |.||  |..      . .| |.||        |..|.                    .|.|||||.    |.| ..||| ..  .|.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR--------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Phosphatase PTPRF.AA Subfamily.N6.PD 1347-1604 42 4.1e-77 251.0 In-house 9-290 (295) Show / Hide 
Range on Protein: 1347-1604
Range on HMM: 9-290/295
Sequence Identity: 42% (119 aa)

NDGLKFSQEYESI---DPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSI-DGVPGSDYINANYID--------GYR-----KQNAYIATQGPLPE
.. | |..|.|..   .  .... ....   || |||| |.. .||.||||.   . ||||||||||||.        |       .|. ||||||.|..
sqtlgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkd

TMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE-TCGLIQVTLLDTVELATYTVRTFAL-HKSGSSEKRELRQFQFMAWPDHGVPEYPTPIL
|. |||||||.. .  .||.|.  |. . || .|||...|. . | |.|| ..  . |.||.|.| . ||.  .|.||..|..|||||||||. |  .| 
tvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvl

AFLRRVKACN--PLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHE---KTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL
||. |.. .    .|||.|||||||.|||| |||||..|. ....     .||.  .. .||||  .||||.|||.  |.  
nfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykav
Phosphatase PTPRF.AA PTPc 1351-1609 37 2.4e-140 473.46 SMART 1-308 (308) Show / Hide 
Range on Protein: 1351-1609
Range on HMM: 1-308/308
Sequence Identity: 37% (118 aa)

KFSQEYESIDPGQQF----------TWENSNLEVNK--PKNRYA-NVIAYDHSRVILTSIDGV----PGSDYINANYIDGYRKQNAYIATQGPLPETMGD
.|..|.|...  ..           ........ |.   ||||  ....|||.||.|....|     .|||||||||||||.....||.||||||.|  |
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMVWEQRTATVVMMTRLEEK--------SRVKCDQYWPARGTETCGLIQVTLLDTVELA-TYTVRTFALHKSGS--------SEKRELRQFQFMAWPD
||||||.|.....||.....||         |.||.||||   ..| | |.||..... ..  ||.||| . . |         ||.|.........|||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPD

HGVPEYPTPILAFLRRVKACNPLD-------------------AGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQY
||||| |...|.|.|.|.....                     .||.|||||||.||||.|..||.|......   |||.. |  ||.||..|||||.||
HGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQY

VFIHEALLEAAT
.|.....|| . 
IFCYRCILEYIK
Phosphatase PTPRF.AA Y_phosphatase 1375-1606 49 7.50000000001e-138 469.05 Pfam 1-243 (243) Show / Hide 
Range on Protein: 1375-1606
Range on HMM: 1-243/243
Sequence Identity: 49% (121 aa)

NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDG-YRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSR-VK-CDQYWPA---RG
||.|||| ....|||.||.|..|.| ..||||||||||| |....|||.||||.|.|..|||||||.|.....||.....|..| .| |.||||     .
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

TETCGLIQVTLLDTVELATYTVRTFALHKSGS--SEKRELRQFQFMAWPDHGVPEY-PTPILAFLRRVKACNP-LDAG--PMVVHCSAGVGRTGCFIVID
..|.| .|||. .. ... |||||| . . |.  .|.|.........||||||||  |...| |.|.|. ..|  |.|  |.|||||||.||||.|..||
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAID

AMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
.|...|.||.||||.. | .||.||..|||||.||.|.....||
IMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase PTPRF.AA Subfamily.R_Anemone_2.PD 1352-1607 51 3.5e-116 378.9 In-house 2-260 (262) Show / Hide 
Range on Protein: 1352-1607
Range on HMM: 2-260/262
Sequence Identity: 51% (133 aa)

FSQEYESIDPGQ--QFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM
.|.||| ... .  ..|..... .||| ||||||..|||..|| |. ..|..||||||||||||||...||||||.|||||.||||||||| .|..||.|
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACN-PLDAGPMVVHC
..||....|...||| .|... | ..|.| ..|||..|..|.| .......|.|..|||.. .|||.|||| .. .|...|.|.. . . .|||.|||||
tqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhc

SAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
||||||| ||..|..|||.|.|..||... |. .|.||| ||||.|||.||...|||| 
saGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvllea
Phosphatase PTPRF.AA Subfamily.R_Anemone_1.PD 1352-1607 48 1.4e-102 334.4 In-house 2-256 (258) Show / Hide 
Range on Protein: 1352-1607
Range on HMM: 2-256/258
Sequence Identity: 48% (123 aa)

FSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTR
...|.. .. ......| .. . || |||||...|.|||||.|.. .. . |||||| |.....|..|.||||.||.||..|||||||.......||.| 
yaaefqrlkeikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtn

LEEKSRVKCDQYWPArGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAG
|.|..  || ||||  .||. | ..|.|  . . | |..||..|.|....|.||..|..|. |||.|||.| | .|...|.|.. .  .| |.|||||||
liegekkkchqYwPd-stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaG

VGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
||||| |.|||||||..|.||.|||.  |. .|..| .||||..||||||.|.|||
vgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavlea
Phosphatase PTPRF.AA Subfamily.RB.PD 1352-1607 48 1.4e-100 327.6 In-house 2-259 (261) Show / Hide 
Range on Protein: 1352-1607
Range on HMM: 2-259/261
Sequence Identity: 48% (125 aa)

FSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMT
||.|||..   |.. . ......||. |||. |...|||||| |....  ...||||||||.||.... |||||||||||. ||||||||... ..||.|
fseeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

RLEEKSRVKCDQYWPARG-TETCGLIQVTLLDTVELATYTVRTFALHKsgSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLD--AGPMVVH
.| || ..||..||||   . . | |.|||| . || ....|.|...|   .|||..||..|..|||||||| ....|.|.|.|.     .  ..|.|||
qlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvH

CSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
||||||||| || .| .|...... .||..| |. .|..||..||||.||.||||.||. 
CsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl
Phosphatase PTPRF.AA Subfamily.RG.PD 1352-1607 43 3e-98 320.1 In-house 2-262 (264) Show / Hide 
Range on Protein: 1352-1607
Range on HMM: 2-262/264
Sequence Identity: 43% (113 aa)

FSQEYESIDP--GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM
.....| |     .... | |. | || |||..|..|...||| |... |. |.|||||.||||||....||.|||||.||. |||||.||......||.
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

TRLEEKSRVKCDQYWPA-RGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRE--LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVV
| |.|| | ..|.|||.  ...... ..||||.. .|..||||.| |..    ...|   ||...  |||.|.||. .. | |.. .|.|. .|||.|||
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivv

HCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
.||||||.| .|..|..|.....|..|..|. .  .|..|...|.||.|||||..||||. 
hdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel
Phosphatase PTPRF.AA Subfamily.R_Sponge_2.PD 1352-1607 43 3.5e-98 319.9 In-house 2-260 (262) Show / Hide 
Range on Protein: 1352-1607
Range on HMM: 2-260/262
Sequence Identity: 43% (113 aa)

FSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSiDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTR
. .|..|.   ..|. ....|. |..|||......||.||| |.. ||...||||||...|||....|||||||||.||..||||||||... |.||.| 
leeeeksveketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltn

LEEKSRVKCDQYWPAR--GTETCGLIQVTLLDTVELATYTVRTFALHK-SGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRV-KACNPLDAGPMVVH
|||. . || .||| .  .. . | ..||| .. .|| |..|.. | | ..|.......||.|.|||.|.||.. |..|....|| .| .    ....|.
leengkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvv

CSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
||.|||||| ||..|..|||.|.|...|..  .  .|..|...||...||||||.||||.
CsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalley
Phosphatase PTPRF.AA Subfamily.RA.PD 1364-1606 48 5e-98 319.3 In-house 16-263 (266) Show / Hide 
Range on Protein: 1364-1606
Range on HMM: 16-263/266
Sequence Identity: 48% (120 aa)

QFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQY
. . . .|.| || |||. ... ||.|||||. ..|.. |||||| .|||||... .||.|||. ||. |||||.|||..||.||.| |.|.. || |||
keklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqy

WPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGS----SEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAG-PMVVHCSAGVGRTGCF
|  |. | | |.|.. |...| .|||| | ... .      ..| .||| | .||. |||  .  .| .|..||....  |.|.|||||||||||| |||
wpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtf

IVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
.||.|||.| |. .|... |  .| ||  ||||. ||.||...|||  
ivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle
Phosphatase PTPRF.AA Subfamily.RK.PD 1352-1607 41 1.2e-95 311.3 In-house 2-265 (267) Show / Hide 
Range on Protein: 1352-1607
Range on HMM: 2-265/267
Sequence Identity: 41% (110 aa)

FSQEYESI----DPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVpGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVV
. .|.|..      .|.  .. . .. |. |||. ...|||.|.|.|.|.||   ||||||..||.|.. .|.|.|||||.||. ||||.|.....|..|
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

MMTRL-EEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHK--SGSSEKRELRQFQFMAWPDH-GVPEYPTPILAFLRRVKACNPL-DAG
|.| |  |..|||| .|||  .. . | |.|.|...  .| . ||.|...|   | .|.||.|||||..||.. .||.. . .|...||||. ..  ..|
mlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeG

PMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
..||||.|| ||.|.||.|| .|| ...|..||..  |  .|...  ||.||.||.|.... |||
rivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvilea
Phosphatase PTPRF.AA Subfamily.N9.PD 1364-1608 44 9.1e-87 282.6 In-house 15-274 (275) Show / Hide 
Range on Protein: 1364-1608
Range on HMM: 15-274/275
Sequence Identity: 44% (108 aa)

QFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQY
. | ..|.| .|  ||||..|. ||..|| |...|. . |||||||..|||....|.|||||||..|. |||||||||.. ..||.||..|.|.|| |||
eGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqy

WP--ARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAC-------------NPLDAGPMVVHC
|     ..  | ..|. .....   |.||.. .... ..|.|..  |||..|||.|||.  . .| .|..|..|.  |.|||||||.|||| || .|  |
wpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhc

SAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA
.|.... |||.   |  .|.|| ...||..||.| . |.|| |                 
saGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya
Phosphatase PTPRF.AA Subfamily.N_Choan_1.PD 1352-1607 40 3.5e-86 280.5 In-house 2-260 (262) Show / Hide 
Range on Protein: 1352-1607
Range on HMM: 2-260/262
Sequence Identity: 40% (106 aa)

FSQEYESIDP-GQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMT
| .|||..   |.. | . |. . |. ||||.|..|||..|| .|  .    .||||||...||.....|||||||.|... .||.|||||.  ..||.|
fieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvt

RLEEKSRVKCDQYWPARG-TETCGLIQVTLLDTVELATYTVRTFALhKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDA-GPMVVHC
|  |....|| .|||    . . | ..|. | . | .||  |.| | .  |.|.||..|....||||||||. .. .| | . |. ..  .   |.|.||
reieagklkChryWPdenselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihC

SAGVGRTGCFIVIDAMLERMKHEKTV-DIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
||||||||..| .| ........... |.   |. .| .||.||||  || |..|.|.| 
saGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavlda
Phosphatase PTPRF.AA Subfamily.N12.PD 1363-1606 41 8.7e-81 262.6 In-house 20-267 (270) Show / Hide 
Range on Protein: 1363-1606
Range on HMM: 20-267/270
Sequence Identity: 41% (104 aa)

QQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQ
.... |... |.|. |||| ... ||.|||.|. |....||||||||.| | ... .|||.|||||.|. |||||.||...  |||. |.| .. ||..|
kvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCer

YWPARGTETC--GLIQVTLLDTVELA-TYTVRTFALHKSgsSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFI
|| .| |..  | ..||| .   .   ...||......  .|.|...||...||||||||. ....|.... |.  .  ..|.||||||||||||  |.|
yWpeegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtii

VIDAMLERMKHEKT---VDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
| . | .|.||.   .|..  |. .| ||. .|||..||.....|..|  
aidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae
Phosphatase PTPRF.AA Subfamily.R_Ecdysozoa.PD 1351-1607 37 2.5e-79 257.9 In-house 1-267 (269) Show / Hide 
Range on Protein: 1351-1607
Range on HMM: 1-267/269
Sequence Identity: 37% (100 aa)

KFSQEYESIDPG--QQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM
|. .|||...     . . ..|. . |. |||| ...|.|. ||.|. | |   ||||||..| ||.... .|| |.|. .|.||||||..||   ..||
kleeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivm

MTRLEEKSRVkCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSG---SSEKRELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNPLD----
.. |.||.|  |..|||   .   | | |.| .. .   |. |.. . | .     ..|.. |....|. |  ||| .. .| ....|.  . |.     
lsnlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsg

-AGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
 .|.||||||||||.| |. .| .|...| |..|||.  |  .|||||.||  .||||.. ||..   
srsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralady
Phosphatase PTPRF.AA Subfamily.N13.PD 1369-1607 42 4e-77 250.8 In-house 20-257 (259) Show / Hide 
Range on Protein: 1369-1607
Range on HMM: 20-257/259
Sequence Identity: 42% (104 aa)

NSNLEVNKPKNRYANVIAYDHSRVILTSIDGvpgsdYINANYIDGYRKQ--NAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPA
.. . || |||| ||. ||..||.| .  |     ||||..|     .    |||.|||||||. |||.|||||..  ..|.|   || .|||..||| |
vgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPe

RGTETCG---LIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPlDAGPMVVHCSAGVGRTGCFIVIDA
  ..      ..|.||....| ...||..|...| |.| ||. ...|..|||||||  ..... |...|.  .  ||||.|||||||.||.| .|.||..
rknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPivvhcsaGiGrsGvlitidv

MLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
|. ....| .|.   | ..| ||. .|||.|||.|...|.||. 
vlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailev
Phosphatase PTPRF.AA Subfamily.N3.PD 1365-1607 40 4.6e-74 240.5 In-house 16-259 (261) Show / Hide 
Range on Protein: 1365-1607
Range on HMM: 16-259/261
Sequence Identity: 40% (101 aa)

FTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGvpgsDYINANYID----GYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKC
.. .....  | .|||| ....||. ||.|.. .     |||||||..    .    | ||||||||..|. |||.|||||.. ..||.| ||. |||| 
laisaarkpenlaknryrdilpydatrvklkeset----dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkC

DQYWPARGTE-TCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFI
||||  . | . | ..|..  . |  .| .| . |... ..|.|.. |.|..||||||||. .. .| |..||...   .  |.|||||||.|||| .|.
hqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvli

VIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
..  |  . ... | .   |  || ||  .|||..|| |. ||.|.| 
lletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailka
Phosphatase PTPRF.AA Subfamily.RC.PD 1364-1606 35 8.8e-74 239.9 In-house 15-285 (288) Show / Hide 
Range on Protein: 1364-1606
Range on HMM: 15-285/288
Sequence Identity: 35% (97 aa)

QFTWENSNLEVNKPKNRYANVIAYDHSRVIL-------------------TSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTA
..| . .. | || ||||..|. ||. || |                     ||.  ||.|||| .||.|.| . |||.|||| ||..|||||..|... 
krtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvk

TVVMMTRLEEKSRVKCDQYWpARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAF----------LRRVK
 .||.|.|.|  | || .||   |... | ..| | ||   ..|..| . | ..   . ||. |.|. .|.....|| |  .|.           |...|
vivmltelkeGdrekcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsse

ACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
 .   ..|..|||..|..||| || ..|.|| .. |. ||... |  .| .|  ||..|.||......| | 
afknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlve
Phosphatase PTPRF.AA Subfamily.N5_RR.PD 1365-1606 37 8.8e-74 239.8 In-house 13-262 (265) Show / Hide 
Range on Protein: 1365-1606
Range on HMM: 13-262/265
Sequence Identity: 37% (94 aa)

FTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVP-GSDYINANYIDGYRK-QNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQ
|. |. ..  .. |||| ...  ..|||.|.| ..    |.||||||| ||.. ..||.|||||||.|. |||||......  .||.|.|.|. | || .
fsqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcav

YWPARG----TETCGLIQVTLLDTVELATYTVRTFALHKSGSsEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACN---PLDAGPMVVHCSAGVGRT
|.| .     .|. | ....  ..||   |.||.. |... .  .|..  . . .|||| .|. ....| ... |..      ..|.|||||||.|||||
yfPdaedyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrt

GCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
|| |.  . ....|..||. . |. .| .|  ||||..|| .||.|| .  
GcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
Phosphatase PTPRF.AA Subfamily.N6.PD 1637-1899 39 7.1e-73 237.1 In-house 12-294 (295) Show / Hide 
Range on Protein: 1637-1899
Range on HMM: 12-294/295
Sequence Identity: 39% (110 aa)

TAMELEFKLLASS-KAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPI-RGVEGSDYINASFLD--------GYR-----QQKAYIATQGPLAESTE
... ||. |  .   ..    ... . || |||  ||.|.. ||| |.   . | |||||||....        |       .|| ||||||.| .  .|
lgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvs

DFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER-SARYQYFVVDPMAEYNMPQYILREFKVTD-ARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFI
|||| |. ||..|||.||  | |..|| .|||.|. . ..    |  . | .. .|.||||.|.    | ..|.|.|..|. ||..||||  . ...|. 
dFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfl

GQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGV---VDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
.|.|..|.. . ||| ||||||.|||| || . |||. .. .|.   .|. ...|..|.||  .||||.||.  |.|.  |. 
edvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyi
Phosphatase PTPRF.AA Subfamily.N_Choan_2.PD 1372-1607 38 1.7e-66 215.8 In-house 18-264 (266) Show / Hide 
Range on Protein: 1372-1607
Range on HMM: 18-264/266
Sequence Identity: 38% (94 aa)

LEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQ-NAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE
||  |||....   ..||.| ...  . . ||||||. |. .. ..|||..|||| |. .||||.||... ..||.| ||||| ||..||||.  |.. |
yarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepke

TCGL----IQVTLLDTVELATYTVRTFALHKsgSSEKRELRQFQFMAWPDHGVPEYPT------PILAFLRRVKACNP-LDA-GPMVVHCSAGVGRTGCF
    |.|. | ..    | ..   |.|  ..|.|.|. |.. .|||||||. .        .|. || |.. .  ||  .|..|||||||||||..|.||
kvkladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtl

IVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEA
 ... ....| ||.   .. .| .|  .||. .|| ....|..|     
iaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavvey
Phosphatase PTPRF.AA Subfamily.RN.PD 1367-1606 43 2.3e-64 208.8 In-house 19-261 (264) Show / Hide 
Range on Protein: 1367-1606
Range on HMM: 19-261/264
Sequence Identity: 43% (104 aa)

WENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYI-DGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP
| .. | |  |||...|..|||||| |..      ||||||  | |   .. |||||||||..|. |||.||||| .. .|..|||||...|..|||  |
kevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckrywp

ARGTETCGLIQVTLLD-TVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAM
.|. .. .| |.   .    | ||.| |    .|| | . || |..||..|||  . ..| | |.|  .    . |.|||||.|.||||..|.|| .|||
deGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlv

LERMK-HEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
..   | .||   .  .| ||. .|.|.||. |.  |. |   
lerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
Phosphatase PTPRF.AA Subfamily.N1.PD 1364-1608 37 2.9e-62 202.2 In-house 17-267 (268) Show / Hide 
Range on Protein: 1364-1608
Range on HMM: 17-267/268
Sequence Identity: 37% (95 aa)

QFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGvpgsDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQY
..  ....|. |...||| .|  |||||..| . |     |||||. ..  . .  || ||||||.|.. ||.||||| . .|.|. .. ||..|| |||
eletreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqy

WPARGTE---TCGL--IQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPL--DAGPMVVHCSAGVGRTG
|    |   ..    ..|.|. . .   ..||.. |.   ..| ||. .|..  ||| |||| |. .| || .|.    |  |||.|.|||||.||.| .
wpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsg

CFIVIDAMLERMKHEKT---VDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA
 ..|..| .. ...    |||  ..  .|..|  ..|| ||  |   |.|| |  
tlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiailega
Phosphatase PTPRF.AA Subfamily.N14.PD 1354-1605 34 4.1e-60 194.9 In-house 4-271 (275) Show / Hide 
Range on Protein: 1354-1605
Range on HMM: 4-271/275
Sequence Identity: 34% (91 aa)

QEYESIDPGQQ-FTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVpGSDYINANYIDGY--RKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMT
.||| | . ..  . . ..|..|..|||. .|. |...|| |..      ..||||  |      |.  ||..||||..|. |||.|||||.. .||.|.
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlt

RLEEKSRVKCDQYWPARG----TETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACN-----PLD-
 ||. . |. .|.|  .    | . |  .||   . .  ... ... |.   |.|.|..  .|.. |||||||| ... |||..|..         .   
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseves

----AGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALL
    |..|||||||||||  |. | ... ..|....||   .. .| || ..|||  || |....|.  
vkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvli
Phosphatase PTPRF.AA Subfamily.N23.PD 1387-1608 36 4.3e-56 182.1 In-house 114-349 (350) Show / Hide 
Range on Protein: 1387-1608
Range on HMM: 114-349/350
Sequence Identity: 36% (85 aa)

YDHSRVILT-SIDGVPGSDYINANYIDGYRK-QNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE--TCGLIQVTLLDT
|..|| |  | .    .||||| |.         .||||||...|..||| |||||.. ..||.|. .|. . |||||||..  |  . |..|.| .. .
hdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslksl

VELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACN----PLDA-----GPMVVHCSAGVGRTGCFIVID-AMLERMKHEK
  ..  |.. |...  | .|.. ......|...|||. |  .||||  |...       ..      |...|||||||||| | |.  |. |  ...  .
rssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagng

TVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA
.|   |  .| || ||||..... .. || ||||  
iiniprvvrrlrqqRkymvqkkvilkklyeavleaa
Phosphatase PTPRF.AA Subfamily.N_Nematode_1.PD 1374-1606 34 1.6e-53 173.3 In-house 25-262 (265) Show / Hide 
Range on Protein: 1374-1606
Range on HMM: 25-262/265
Sequence Identity: 34% (83 aa)

VNKPKNRYANVIAYDHSRVILTSiDGVPgSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCG
.. ||||..|   |..||.|.. ...| |||| |||.    . . .| .|.|| .|. ||| ||  ..  ..||. .| ||...|| .|.||.  |.  .
qeadknrykdvgcldknrvklae-eplp-sdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegekle

LIQ------V---TLLDTVELATYTVRTFALHKSGS-SEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAcnplDAGPMVVHCSAGVGRTGCFIVIDA
 .      |   .  ...| .  ....  |. .|. ...|.....|.. |||.|||.    .|.| .|..    . ||.|||||||.||||  ..|. .|
fkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrg----skgPivvhCsaGiGrtGtivaiey

MLERMKHEKTVD-IYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
... ..|... .   |  .|.|||| .||. ||.|.|  ||.  
ildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvlln
Phosphatase PTPRF.AA Subfamily.N_Nematode_4.PD 1370-1606 33 3.8e-49 159.0 In-house 21-261 (264) Show / Hide 
Range on Protein: 1370-1606
Range on HMM: 21-261/264
Sequence Identity: 33% (81 aa)

SNLEVNKPKNRYANVIAYDHSRVILTSIDgvPGSDYINANYIDGYrKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT
|  | |. |||||...  |..||.|   |  |  ||| |...     .  ||.|||||.||. ||| ||.....|.|||.|.|.   || .|.| .  . 
saseknsdknryadilcidetrvvlknrd--pdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypekse

E--TCGLIQVTLLDTVEL-------ATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKAcnPLDAGPMVVHCSAGVGRTGCFIV
 ..|  ..||... |         . .| .   .|  .||.  .. .|.  |.|.  |. ..|.. ... ||   .   .|.|||||||||||  .. ||
kvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrtatlvG

IDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
    |..    ...   |  .|. |   ||.. |..|.   |.|  
idyatirirenseievldivrelramrlkavqshlqflfllvvlie
Phosphatase PTPRF.AA Subfamily.N20.PD 1368-1606 37 1.1e-47 154.4 In-house 19-254 (257) Show / Hide 
Range on Protein: 1368-1606
Range on HMM: 19-254/257
Sequence Identity: 37% (89 aa)

ENSNLEVNKPKNRYANVIAYDHSRVILTSidgvpGSDYINANYIDGY--RKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP
.. |   |. |||| ... || .|| |         |||||.||      ..  ||||||||  |. |||.|| |. .  . |.||  |.|| .|||   
nsgnqpsnreknryrdilpydstrvplgk-----skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywp

ARGTETCGLI--QVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNplDAGPMVVHCSAGVGRTGCFIVIDA
 .   |   .| | .   |  . .| | . .  .   . ..|.||  ||||| |     .. ..|  . .    .||||||||||.|||| |...| .. 
islkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarksh--ltgpmvvhcsagigrtgvflcvdv

MLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
 . .. ...|   |. || ||. ||||..|| | .. .||   
vfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivle
Phosphatase PTPRF.AA PTPc_motif 1505-1606 43 2.2e-46 161.32 SMART 1-92 (92) Show / Hide 
Range on Protein: 1505-1606
Range on HMM: 1-92/92
Sequence Identity: 43% (47 aa)

ELRQFQFMAWPDH-----GVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVF
.........||||     ||||   .|| |.|.|..       |.|||||||.||||.|..|| |...      |||.. |  ||.||. |||||.||.|
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIF

IHEALLE
.....||
CYRCILE
Phosphatase PTPRF.AA Subfamily.R_Nematode_2.PD 1368-1604 28 2.6e-45 146.4 In-house 22-256 (261) Show / Hide 
Range on Protein: 1368-1604
Range on HMM: 22-256/261
Sequence Identity: 28% (67 aa)

ENSNLEVNKPKNRYANVIAYDHSRVILTsIDGVpGSDyINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPAR
..|.  ..| |.|| .|   ....|    .||   .. | ||...   ... .||||||| .|. ||| ||  .   ..||...  ||.. ||..|.| .
tesaaylpkdkhRypdvPCkpetavevi-vdgk-rvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfple

GTET--CGLIQVTLLDTVELATYTVRTFALH---KSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNpldaGPMVVHCSAGVGRTGCFIVID
 ...   | .... ... ....  .   .|.   ..|  . | .. .|.  |||.|||.  . .|  ||  .     |.|||||||.|||. || .. . 
tsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkkse----kPivvhCsaGiGRtmafigte

AMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL
.......|. .   .  .|..|   .||| |. ... ..   
ylareveadptieltealkelrehRwkgiqtesqlywltlga
Phosphatase PTPRF.AA Subfamily.N_Nematode_6.PD 1372-1606 30 6e-42 135.5 In-house 21-250 (253) Show / Hide 
Range on Protein: 1372-1606
Range on HMM: 21-250/253
Sequence Identity: 30% (73 aa)

LEVNKPKNRYANVIAYDHSRVILTSIDgvpgSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPAR----
.  .| .|||.|.  .| .|. |.  .      || ||...   |.. .| ||.|| .|. .||.|.  . .  .||.  ||| . |. .| . .     
flkfkdrnrytniqCcdagrlkladde----dfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGda

--GTETCGLIQVTLLDTVELATytVRTFALHKSGSSEKrELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNpldaGPMVVHCSAGVGRTGCFIVIDAML
  |. |  |...  |   . .    .  . |.|  |   .. ... .|||||||.  .  | .|  || ..     |.|||||||||||| ...|  .||
rkitklctvikigrkdidkilv--rslkrivkagdeev-ivkhihWanWPdhGvPdsflsalrllsvvkkdk----kPivvhCsaGvGrtGtlaliliil

ERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLE
 ... .  ..   .. .| .|   |||| ||.. .  .|| 
ealrlpdfqgvkdllvklreerfravqtevqylyalrcvle
Phosphatase PTPRF.AA Subfamily.N_Nematode_5.PD 1353-1605 26 3.3e-38 123.0 In-house 3-254 (258) Show / Hide 
Range on Protein: 1353-1605
Range on HMM: 3-254/258
Sequence Identity: 26% (68 aa)

SQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRViltsIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRL
..|.| ... .  . . .. | |. |||. .|  .|..||    . . . ..||||..|.    .. .| || |||.|  |||||| ... ..||.... 
ktefeklaslkpnketckafeknlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllved

EEKSRVKCdQYWP-ARG-TETCG--LIQVTLLDTVELA--TYTVRTFAlhkSGSSEKRELRQFQFMAWPDHGVPEYPTPILA-FLRRVKACNPLDAGPMV
|| .. .. ...|   |   . |  .|...  ...|     ||| ...    | ||.  ..  ..  |... ||.  .....  . .|   .  .  |.|
eelketav-sffpletgdylnlgkmfinnrkvevkedekkeytvevlp---egcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvv

VHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALL
|....|.||.| |...... | ....|...|   .  .||||  .|.. .||.....|.|
vvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavl
Phosphatase PTPRF.AA Subfamily.R_Nematode_3.PD 1371-1601 21 6.3e-35 112.4 In-house 19-259 (267) Show / Hide 
Range on Protein: 1371-1601
Range on HMM: 19-259/267
Sequence Identity: 21% (53 aa)

NLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDgYRKQNAYIATQGPL--------PETMGDFWRMVWEQRTATVVMMTRLEE---KSRVK
.|. .  ..|...|. . ..||.|        .|.|.||..    ...  | ||.|.         .|.  || |. .....|||.    |   .   ||
slskkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeek

CDQYWPARGTETCGLIQVTL----LDTVELATYTVRTFALhKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNpldaGPMVVHCSAGVGRT
 .|.|    . . . .|..     ..   .    ||. . .    ..   .  .. .|.....|| | ..|. .. |....     |.|||||.|..|..
cseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk----tpvvVHCsdGisRs

GCFIVIDAMLERMKHEK-TVDIYGHVTCMRSQRNYMVQTEDQYVFIH
.. .|.   . . ..| ..|.   .. .|.||   .||| .. |.  
atlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvi
Phosphatase PTPRF.AA Subfamily.N_Nematode_egg.PD 1365-1604 25 3.7e-29 93.6 In-house 16-252 (257) Show / Hide 
Range on Protein: 1365-1604
Range on HMM: 16-252/257
Sequence Identity: 25% (60 aa)

FTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKsrVKCDQYW
. ...  . .. | |   |   . ||| |    |    |.| ||...|    | .| .| || .|. ||||||.....||.|   |    .|. |||   
islttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyyw

PARGTETC----GLIQVTLLDTVELATYTVRTFALHKS-GSSEKRELRQFQFmAWPDHGVPEYPTPILAFLRRVkacnpldAGPMVVHCSAGVGRTGCFI
.|.     | .... |.  . |    |   |.   |  |.. |  .|   .   ..|  .|  ||..       . |.||..  || ...... |.  | 
pkaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwqg-dvnylsdvysplrvlrklrnl-------skpvvvqdilGvskaatlv

VIDAMLERMKHEKT--VDIYGHVTCMRSQRNYMVQTEDQYVFIHEAL
..    .    .   |  .| .|.. |..  .|.|..  .       
aieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlv
Phosphatase PTPRF.AA Subfamily.N_Fungi_PTP1.PD 1377-1471 37 1.5e-25 81.5 In-house 47-155 (343) Show / Hide 
Range on Protein: 1377-1471
Range on HMM: 47-155/343
Sequence Identity: 37% (38 aa)

PKNRYANVIAYDHSRVILT----SID----GVPGSDYINANYIDGY---RKQN---AYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQ
|||| |.. |.||||.|     | |     . ..|||||||.       ..|    |||||.|||.|. ||.... .....| . |  . ||..||.  .
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr

YWPARGTET
 .       
YWqegsydd
Phosphatase PTPRF.AA Subfamily.N_Fungi_PTP1.PD 1501-1605 38 4.1e-16 50.5 In-house 210-339 (343) Show / Hide 
Range on Protein: 1501-1605
Range on HMM: 210-339/343
Sequence Identity: 38% (46 aa)

SEKRELRQFQFMAWPDHGVPEYPTPILAFLR-------RVKACNPL---DAGPMVVHCSAGVGRTGCFIVIDAMLE----------RMKH----EKTVD-
||  |. |.|.  |.| ..   |  ||  |           | . |    . |..||||||||||| .. .| .|.....     || | |   |  .|.
sepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDl

IYGHVTCMRSQRNYMVQTEDQYVFIHEALL
||  |||. ||..||.||||          
isiivnelrkqrismvqnldqfifiYeall
Phosphatase PTPRF.AA Subfamily.N_Nematode_eak.PD 1377-1533 24 4.3e-15 47.4 In-house 28-182 (281) Show / Hide 
Range on Protein: 1377-1533
Range on HMM: 28-182/281
Sequence Identity: 24% (38 aa)

PKNRYANVIAYDHSRVILTSIDGVPgSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTE-TCGLI
.||  ... .|.  | |||    .   ||||  ..     . || |  .  . .  ||.|| ||.. ..|..    |.| |.|.| .. .   | ..|. 
nrnrvvkivpqdrylvrltssqlnr-dGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevlkyGil

QVTLLDT-VELATYTVRTFALHKSgsSEKRELRQFQFMAWPDHGVPEYPtPILAFLRRV
 .  |. . . .| . |.|    |  ..  ...  | .  .| |    ||. . .    
dverkeyavkrniletrllilrkG--nethrvlhykvfGwtettlpkye-dflalrkvm
Phosphatase PTPRF.AA Family.DSP.PD 1506-1607 19 8.1e-10 30.2 In-house 151-254 (387) Show / Hide 
Range on Protein: 1506-1607
Range on HMM: 151-254/387
Sequence Identity: 19% (20 aa)

LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNpLDAGPMVVHCSAGVGRTGCFIVIDAMLE-RMKHEKTVDIYGHVT--CMRSQRNYMVQTEDQYVFIHE
..  ....||..|     .  ... .. .|  . |  .||| ||.||.|  |..  |   ... |...| .  .   . . . ....| .|.  . .  .
gikylripidDhnapplenlfekaidfieegn-dskgvVlVHCkaGkgRsgtliiaYlmksegltleealdwvrskRpgvitpnqgflkqlkdlekeklk

ALLEA
|    
vssev
Phosphatase PTPRF.AA Subfamily.PTPDC1.PD 1509-1602 29 1.4e-08 26.1 In-house 137-222 (229) Show / Hide 
Range on Protein: 1509-1602
Range on HMM: 137-222/229
Sequence Identity: 29% (27 aa)

FQFMAWPDHGVPEYpTPILAFLRRVKACnpLDAGPMVVHCSAGVGRTGCFIVIDAMlermkHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHE
|  ....|.||.   . ||   . |.    |  | . ||| || ||||  |    .     . | ..    .. .||.|   .|| .|...|  
fynfglkDygvasl-eriLdivkvvdfa--leegkiavHCHAGlGRtGvliacylv-----yakrltaeeaiklvrskrpksiqtreqvelvee
Phosphatase PTPRF.AA Subfamily.N_Nematode_eak.PD 1529-1606 27 8.5e-08 23.4 In-house 201-278 (281) Show / Hide 
Range on Protein: 1529-1606
Range on HMM: 201-278/281
Sequence Identity: 27% (22 aa)

FLRRVKACNPLDAgPmVVHCSAGVGRTGCFIVIDAMLeRMKHEKTVDIY---GHVTCMRSQRNYMVQTEDQYVFIHEALLE
.|.. .   |  | | .. .. |  |.| |.||| .. |.  .|  . |     .  ..|.|.. | .. |. ||.|..|.
tlkkyihtppsfa-p-iiqsarGsaraGvfvvidlli-rlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivld
Phosphatase PTPRF.AA Subfamily.CDC14.PD 1529-1564 36 9.2e-06 17.1 In-house 190-221 (258) Show / Hide 
Range on Protein: 1529-1564
Range on HMM: 190-221/258
Sequence Identity: 36% (13 aa)

FLRRVKACnpldAGPMVVHCSAGVGRTGCFIVIDAM
||. .  .     | ..||| ||.||||..|    .
fleiteka----eGaiavhCkaGLGrtgtligcyli
Phosphatase PTPRF.AA PTPc 1638-1900 38 2.2e-131 443.69 SMART 1-308 (308) Show / Hide 
Range on Protein: 1638-1900
Range on HMM: 1-308/308
Sequence Identity: 38% (121 aa)

AMELEFKLLASSKAHTS--------RFISANLPCNK--FKNRLV-NIMPYELTRVCLQPIRGV----EGSDYINASFLDGYRQQKAYIATQGPLAESTED
  . ||. | . . . .        .. .|..|.|.   |||   .|..|. |||.|.|. |     ||||||||.. |||...|.||.||||| .  ||
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMLWEHNSTIIVMLTKLREM--------GREKCHQYWPAERSARYQYFVVDPMAEYNMP-QYILREFKVTDARD--------GQSRTIRQFQFTDWPE
|||| |.....|||||... |.        |||||||||| | .  |  . |  . |...|  |..|.|.||.  .        ...||......|.||.
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPD

QGVPKTGEGFIDFIGQVHKTKEQFGQ-----------------DGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQY
.|||.. ..|.||| ||.........                 .||| ||||||.||||.|....|......    ||.||.||..|.||| |||||.||
HGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQY

QLCYRAALEYLG
. |||..|||. 
IFCYRCILEYIK
Phosphatase PTPRF.AA Y_phosphatase 1664-1897 49 3.8e-124 423.54 Pfam 1-243 (243) Show / Hide 
Range on Protein: 1664-1897
Range on HMM: 1-243/243
Sequence Identity: 49% (121 aa)

NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDG-YRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGR-EK-CHQYWPA---ER
|| ||| ..| .|. |||.||||.| |.||||||.. || |...||||.||||. .. |||||| |....|.||||... |||| || ||||||    ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

SARYQYFVVDPMAEYNMPQYILREFKVTDARD--GQSRTIRQFQFTDWPEQGVPKTG-EGFIDFIGQVHKTKEQFGQDG--PITVHCSAGVGRTGVFITL
. .|  | |  . |. .| |..|.|.||.  |  ...||......|.||..|||...  ...||| ||.| ..  ...|  ||.||||||.||||.|...
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQP-NPDHGCPPIVVHCSAGCGRTGTFCAI

SIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
.|....|. ||.||.||.||..|.||| |||||.||. ||.. ||
DIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase PTPRF.AA Subfamily.R_Anemone_2.PD 1639-1899 51 8.20000000001e-111 361.4 In-house 2-261 (262) Show / Hide 
Range on Protein: 1639-1899
Range on HMM: 2-261/262
Sequence Identity: 51% (135 aa)

MELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML
.. |.. |. |....... ||. |.||.||| .||..|. ||| ||.. |.||||||||...||||..|||||||.||.|  ||||||.|| ||..||||
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQdGPITVH
|...| |. |.|.||| . |  |.  ||. . | .. .|.||.|||.  .  ..|..|||..|.||..|||. | ...|...||.|.... |. |||.||
tqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesga-gpivvh

CSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
||||||||||||...|.|||.. |..||.|||||.||.||..||||.|||...| . ||.|
csaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal
Phosphatase PTPRF.AA Subfamily.RA.PD 1639-1899 49 3.2e-97 316.7 In-house 2-265 (266) Show / Hide 
Range on Protein: 1639-1899
Range on HMM: 2-265/266
Sequence Identity: 49% (132 aa)

MELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML
.| ||| |.| | . ...  ||.. || |||.|.|.||. .|| |. ..|.| ||||||||.||||... .||.|||..|. ||||||.||..|. ||||
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativml

TKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVT----DARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDgP
|.|.| ..|||.|||| | .  |    |    |  . .| .|.| ||     .|. .|| .||| || ||| ||| .| | .... .|.|...| ..  |
telkerkeekcaqywpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanh-p

ITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|.||||||||||| ||.|. ||||.. |...|.|..||.||.||| ||||. ||...|.. |||.
ivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlleyi
Phosphatase PTPRF.AA Subfamily.R_Sponge_2.PD 1651-1899 44 5.4e-90 293.0 In-house 12-261 (262) Show / Hide 
Range on Protein: 1651-1899
Range on HMM: 12-261/262
Sequence Identity: 44% (112 aa)

AHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPiRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCH
.   .  |.|. |. ||| ..|.||. .|| |..  |...||||||||.|||...|||||||||| |. ||||||.|| ....|||||.|.| |.|||..
etefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekca

QYWPAE--RSARYQYFVVDPMAEYNMPQYILREFKVTDARD-GQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGqDGPITVHCSAGVGRTG
||| .   ...| .|.|    | ....||.|..|.....  .......||.|. |||..|||.   ....| .|...... | ...|||.||.|||||| 
kYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksg-nkaitvvCsdgvgrtG

VFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
||.| .||||.. |...|.|...|||||.|. .||...||. .. |.|||. 
tfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi
Phosphatase PTPRF.AA Subfamily.RB.PD 1654-1898 42 2e-86 281.2 In-house 16-259 (261) Show / Hide 
Range on Protein: 1654-1898
Range on HMM: 16-259/261
Sequence Identity: 42% (105 aa)

SRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYW
.   .|....|. |||  ||.||. .|| |. ..  ...|||||....||.... |||||||| |...|||||.||..|.||||||.| | |.|||..||
qavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYW

PAER-SARYQYFVVDPMAEYNMPQYILREFKVTDarDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITL
||.. .  |    |. .|| .. ....||||..   . ..|..||..|| ||. |||.. .  .||. .|... |.  ...|||||||||||||.||.| 
PadeepvlyGdikvtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfial

SIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
 .|.... . .||.| .|  ||..|  .||||.|| . ... |.. 
drllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl
Phosphatase PTPRF.AA Subfamily.R_Anemone_1.PD 1640-1899 39 1.8e-85 278.4 In-house 3-257 (258) Show / Hide 
Range on Protein: 1640-1899
Range on HMM: 3-257/258
Sequence Identity: 39% (103 aa)

ELEFKLLASSKAHTSRfiSANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLT
. ||. | ..|....   .|. ..|| |||  .|.... .|| |.   . | |||||||.|.......|.||||.|| |..||||||.|......|||||
aaefqrlkeikeeeke--varkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLt

KLREMGREKCHQYWPAeRSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTkeQFGQDGPITVHC
 | |.  .|||||||  ....|  . |  . . .. .||.|..... ..  ..|...|..|| ||..|||..    ...  .|.|.  .  .. |. |||
nliegekkkchqYwPd-stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqks--slagarpvvvhC

SAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
||||||||.|. .. .||... | |||.|..||..|..|| ||||..||...| ||.|  
saGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal
Phosphatase PTPRF.AA Subfamily.RG.PD 1639-1897 39 4.2e-85 277.0 In-house 2-261 (264) Show / Hide 
Range on Protein: 1639-1897
Range on HMM: 2-261/264
Sequence Identity: 39% (104 aa)

MELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML
.| .|... ..|..  .  |.. ..|| ||| .||...| .|| |.|. |..|.||||||..||||..|.||.|||||.| .||||||.||||..|||||
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

TKLREMGREKCHQYWPA-ERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRT--IRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQfgQDGPI
|.| | ||.....|||. . . ... . |  ... .. .|..|.| . . .| ....  .||...|.||..|.|.    .. |..  .....  . |||.
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaanke--eaGPi

TVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
||.||||||.|..| |. .|.....|  |...|..|..|..|| .|.||.||.  | | || 
vvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydalle
Phosphatase PTPRF.AA Subfamily.N9.PD 1651-1898 44 1.3e-83 272.2 In-house 13-273 (275) Show / Hide 
Range on Protein: 1651-1898
Range on HMM: 13-273/275
Sequence Identity: 44% (110 aa)

AHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCH
. . .|  ..|..|  |||  ... |. ||| |. . . | ||||||.|.|||.|.||.||||||| ....|||||.||..  .||| |..|.|| || |
pveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcg

QYWPA--ERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFG-----------QDGPITV
|||   | ||..  . |  .   .. .|  | ..........||..  |||. ||. |||.... ..|.. .| ... .... || ||||||.|||| ||
qywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivv

HCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
|| | |.|.. .|.||...|||.|||||  ..||..||..|| | |||             
hcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
Phosphatase PTPRF.AA Subfamily.RK.PD 1643-1899 40 1.5e-83 271.7 In-house 6-266 (267) Show / Hide 
Range on Protein: 1643-1899
Range on HMM: 6-266/267
Sequence Identity: 40% (107 aa)

FKLL--ASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVeGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTK
|. |   . . ..  . .| .. |. |||  .|..|. ..| |... |   ||||||...|.|.. .|.|.||||| | ..||||.....|.. |||||.
fetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmlte

L-REMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTD-AR-DGQSRTIRQFQFTDWPEQ-GVPKTGEGFIDFIGQVHKTKEQfGQDGPIT
|  | || || .||| . . ||. . |  .      ... | |.|.  ||   . |..|||||. |||  .||.  ......|.|.|..|. ...|.| |
ldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqee-eeeGriv

VHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
||.|| ||.|.||...|||| .. |||||.|..|||||.... ||.||.||...| ..||.| 
vhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal
Phosphatase PTPRF.AA Subfamily.R_Ecdysozoa.PD 1639-1898 38 7.3e-80 259.6 In-house 2-267 (269) Show / Hide 
Range on Protein: 1639-1898
Range on HMM: 2-267/269
Sequence Identity: 38% (103 aa)

MELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML
.| |.. | ..         ..   |..|||  .|.... ||| |..| | | ||||||||. ||...| .|| |.|. .  .|||||..| ..|.||||
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivml

TKLREMGREkCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR---DGQSRTIRQFQFTDWP-EQGVPKTGEGFIDFIGQVHKT---KEQFGQ
..| |. |. |..||| |   .|.  .|... | ....|| ||..|.        .|| . |...||. .. ||.. .| ...| ||..    ... |  
snlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgs

DGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
.||.|||||||||.|.|..|...|.... |  ||.|.||| || ||..||  .||. .||| ..|  
rsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralady
Phosphatase PTPRF.AA Subfamily.N12.PD 1657-1898 40 1.1e-77 252.5 In-house 25-268 (270) Show / Hide 
Range on Protein: 1657-1898
Range on HMM: 25-268/270
Sequence Identity: 40% (100 aa)

ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAE
... . |. |||  .|.||. .|| |. |...||||||||.|. | .....|||.||||..  .|||||.||.| .|.||. .. |.|.||..||| |  
eagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpee

--RSARYQYFVVDPMAEYNMP-QYILREFKVTDArdGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfGQDGPITVHCSAGVGRTGVFITLS
.. ... | |. ..| ..  ....| .||.    ..||...||..|.||..|||.. .  ...| .|....|   .| |.|||||||||||. |.. .| 
geeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqe--sedaPlvvhCsaGvGrtGtiiaid

IVLERMRYEGV---VDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
| .. | .   .|.|. | .||.||.|.|||..||.| |.| .|.   
yvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael
Phosphatase PTPRF.AA Subfamily.N_Choan_1.PD 1658-1899 38 8.5e-75 243.2 In-house 20-261 (262) Show / Hide 
Range on Protein: 1658-1899
Range on HMM: 20-261/262
Sequence Identity: 38% (94 aa)

SANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER
... . |. ||| .||. |. ||| ..|    . .|||||.|..||...|.|||||||. .| ..||.|.||.. ..|||.|.| |. |||.||| |. .
askadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWPden

-SARYQYFVVDPMAEYNMPQYILREFKVtDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQdGPITVHCSAGVGRTGVFITLSIVL
 ..  ..|  ..| . ..|| |.||. ....|..|...|...| ||..|||.| . ...|  .|.|....  .  |. .||||||||||..|.|  ....
selklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktk-aplvihCsaGvGrtGtyialDrlv

ERMRYEGVV-DMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
.. .  . |. ..|. || .|  ||||  ||.  |.| |..|  
kaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal
Phosphatase PTPRF.AA Subfamily.N3.PD 1656-1891 42 7.6e-71 230.0 In-house 18-252 (261) Show / Hide 
Range on Protein: 1656-1891
Range on HMM: 18-252/261
Sequence Identity: 42% (100 aa)

FISANLPCNKFKNRLVNIMPYELTRVCLQpirGVEGsDYINASFLD----GYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQ
|..| |  |||  .|.||. ||| |.     |  |||||....    .  . . |||||||||....|||.|.||..||.||||| | ||| ||||||| 
isaarkpenlaknryrdilpydatrvklk---eset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChq

YWPAE-RSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfGQDGPITVHCSAGVGRTGVFI
.  . ..  | |    | .  .|.|||. ..|..  ..|.| |.|...||..|||.  . |..|. .|.|...  |.. |. ||||||.|||||.|.| .
yWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrs--gkeePvvvhCsaGigrtGvli

TLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLC
 |  .  .  | . . |.|.| || ..|||..||..     
lletalalieaaepvypldivrtmrdqramlvqtvsqykfv
Phosphatase PTPRF.AA Subfamily.N5_RR.PD 1660-1899 37 5.1e-70 227.5 In-house 19-264 (265) Show / Hide 
Range on Protein: 1660-1899
Range on HMM: 19-264/265
Sequence Identity: 37% (91 aa)

NLPCNKFKNRLVNIMPYELTRVCLQPIRGVEG-SDYINASFLDGYRQ-QKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER
... .. |||  .|.| | .||.|..  . .  |.|||| .. ||.. .|||.||||||..  .|||||........|||||||.|. |.||..|.| ..
evfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdae

SA----RYQYFVVDPMAEYNMPQYILREFKVTDARDgQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQD-GPITVHCSAGVGRTGVFITL
..    ||. . .      .  .| .|.. .. ...  .|..  . .||||.. .|.  . ..|.. .|....|.  ..|. ||||||.||||.||. ||
dyeiserygdveikveeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiai

SIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
 . ..| |.|||....|  || .|  ||||..||.| .||  .||  
siavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl
Phosphatase PTPRF.AA Subfamily.N_Choan_2.PD 1664-1898 35 7.1e-68 220.3 In-house 21-264 (266) Show / Hide 
Range on Protein: 1664-1898
Range on HMM: 21-264/266
Sequence Identity: 35% (87 aa)

NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQ-QKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQ
||  ||  .|.|   |||.|....  . . |||| .. |. . .|.|||..|||. ....||||.||...| |||.|.| | ||.|| .|||||.  . .
nkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk

Y----FVVDPMAEYNMPQYILREFKVTDarDGQSRTIRQFQFTDWPEQGVPKTGE------GFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITL
.      |  ..| ..  |||.. ...   .|..|... |....||..|||.. .        .. . .|....... . .|. |||||||||||..|..
ladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliai

SIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
 |... .  .. ||. . .. || .|.|.||. .||.| |.| .||
DiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavvey
Phosphatase PTPRF.AA Subfamily.RC.PD 1640-1898 37 1.2e-67 219.8 In-house 3-286 (288) Show / Hide 
Range on Protein: 1640-1898
Range on HMM: 3-286/288
Sequence Identity: 37% (107 aa)

ELEFKLLASSKAHTSRFIsANLPCNKFKNRLVNIMPYELTRVCL-------------------QPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAEST
| ||. | | ... .  | |. . || ||| ....||.  || |                   . | . |||.||||||.|.|.. . |||.|||| |. 
eaefqrlpsvrskrtiki-arkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketv

EDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWpAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIG
.|||||..|.  ..|||||.|.|  |||| .||  |    |   .||   . . ..|||| ... . .. .||.. |.|.|.|.....|.  . ....| 
ddfwrmiferkvkvivmltelkeGdrekcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliq

QVHK------TKEQF--GQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
 |..      . | |   . .|. |||..|..|||.||.|  .|| .  | .||.|| || || .|| ||..|.||.| | .  |.
vvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet
Phosphatase PTPRF.AA Subfamily.N13.PD 1659-1899 38 6.9e-67 217.3 In-house 21-258 (259) Show / Hide 
Range on Protein: 1659-1899
Range on HMM: 21-258/259
Sequence Identity: 38% (93 aa)

ANLPCNKFKNRLVNIMPYELTRVCLQpirgVEGSdYINASFLDGY--RQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAE
..   || |||  |..||. ||| |.     ||. |||||..      ..  |||.|||| |...|||.|.|| ....|.|.|. .| |.|||.||| ..
gkkkenkdknryrnvlPydetrvklg----degg-yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPer

RSAR---YQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfgQDGPITVHCSAGVGRTGVFITLS
. .   .. . |. .   .. .. .|...|.| . |.|| . ...|..||. |||.. . .. |. .|.. ..   . |||||||||.||.||.||. .|
knkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt---dagPivvhcsaGiGrsGvlitid

IVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|. .  .  .|. ..|..|| || ..|||.||| ..|.|.|| |  
vvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl
Phosphatase PTPRF.AA Subfamily.N14.PD 1644-1899 32 9.5e-64 206.9 In-house 7-274 (275) Show / Hide 
Range on Protein: 1644-1899
Range on HMM: 7-274/275
Sequence Identity: 32% (87 aa)

KLLASSKAhTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVeGSDYINASFLDGY--RQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKL
..  ..  . . .|.|| |. |||  ...||| .|| |.| .    ..||||| .      ... ||..|||| .. .|||.|.||....|||||. .| 
eripkkre-dallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmltee

REMGREKCHQYWPAE----RSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQ------
|.||...|.| .    ...... | |      . ...| . .|.     .. ||.  .|.||||..|||.  .||..|..|.  .... .        . 
eedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvk

--DGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|. |||||||||||| |.  .... .  . ..|. .....||.||  .|||  ||.. |.. ..||    
eskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikyl
Phosphatase PTPRF.AA Subfamily.RN.PD 1640-1896 39 5.6e-61 197.7 In-house 3-260 (264) Show / Hide 
Range on Protein: 1640-1896
Range on HMM: 3-260/264
Sequence Identity: 39% (103 aa)

ELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFL-DGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML
| |.. |.. .|. |    |. . |  |||  ...||. .|| |.     | |||||||.. |   .. |||||||||...  |||.|.||....||.||
ekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnl

TKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNM-PQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfGQDGPITV
.|.| | ..|..||| | |. |. . |. ..|.    .|..| | . . .  ..||. || |  |||.||| .   ...|  .| |.    |.  || ||
trleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyr--Grscpivv

HCSAGVGRTGVFITLSIVLERMRyEG--VVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAAL
||.|.|||||.| . .||||.   |   .|.  |.. || ||| .|.|.||..... |   
hcsdGaGrtGvyilidlvlerll-kGvkeidiaatlehlrdqrpglvktkdqfefaltava
Phosphatase PTPRF.AA Subfamily.N23.PD 1679-1898 34 1e-56 184.1 In-house 117-348 (350) Show / Hide 
Range on Protein: 1679-1898
Range on HMM: 117-348/350
Sequence Identity: 34% (80 aa)

TRVCLQ-PIRGVEGSDYINASFLDGYRQ-QKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSA--RYQYFVVDPMAEYNM
.||.||   .  . .|||||..|         .||||||.|..  ||| |.||  | .||||||  |... ||.||||... .   .. .|    . . .
nrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrss

PQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTK-----EQF--GQDGPITVHCSAGVGRTGVF-ITLSIVLERMRYEGVVD
..| | ....     . |.. ....| |.| ||||  | ...|.|.|...       .     . || .||||||||||.|.  |.. |    .|.... 
egwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngiin

MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
. |..|| ||  |||...... .|.| ||.  
iprvvrrlrqqRkymvqkkvilkklyeavlea
Phosphatase PTPRF.AA Subfamily.N20.PD 1650-1899 40 1.7e-54 176.8 In-house 12-256 (257) Show / Hide 
Range on Protein: 1650-1899
Range on HMM: 12-256/257
Sequence Identity: 40% (100 aa)

KAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQpirgvEGSDYINASFLDGY--RQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGRE
|     | | | |.|. |||  .|.||. ||| |      .  ||||||..      ..  ||||||||  . .|||.|. | || .| |.|.  | |  
knlpgefnsgnqpsnreknryrdilpydstrvplg-----kskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggii

KCHQYWPAE--RSARYQYFVVDpMAEYNMPQY-ILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKeqfgQDGPITVHCSAGVG
||..|||    .    ..| |  . .|.. || |.| |.| .   | |....|.||| ||..| | . . || .|   .|..||. ||||||.||||||.
kcyhywpislkkplelkhfrvf-lenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarksh----ltgpmvvhcsagig

RTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
 . .|.  .  .  ..... |  .| ||  ||||..||..||   || |      
rtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl
Phosphatase PTPRF.AA Subfamily.N1.PD 1650-1897 33 1.3e-51 167.3 In-house 14-265 (268) Show / Hide 
Range on Protein: 1650-1897
Range on HMM: 14-265/268
Sequence Identity: 33% (83 aa)

KAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGvegsDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKC
| .  .  .|.|| |. .||  .. ||. .|. |.        ||||||...  . .. || |||||.. .. ||.| ||.||  ..|| |.| .. ||.
kekeletreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikC

HQYWPAERSA---RYQY--FVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVG
|||| |...    ..   . |  ..| .  ....| ....| .. ..|.| .|..| ||. |||..   |..|. .|.... ||. .|||||.||.| . 
aqywpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagig

RTGVFITLSIVLERMRYEGV---VDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
 .. .| ..  .|    ||. . .  || .|  ..|| || .  | | ||      
rsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile
Phosphatase PTPRF.AA PTPc_motif 1794-1897 43 4.1e-46 160.45 SMART 1-92 (92) Show / Hide 
Range on Protein: 1794-1897
Range on HMM: 1-92/92
Sequence Identity: 43% (47 aa)

TIRQFQFTDWPEQ-----GVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQY
|......|.||..     |||.  .....|| .|.|         || ||||||.||||.|.........      ||.||||| .|.||| |||||.||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK---------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQY

QLCYRAALE
. |||. ||
IFCYRCILE
Phosphatase PTPRF.AA Subfamily.N_Nematode_1.PD 1663-1899 29 4.2e-46 149.0 In-house 25-264 (265) Show / Hide 
Range on Protein: 1663-1899
Range on HMM: 25-264/265
Sequence Identity: 29% (74 aa)

CNKFKNRLVNIMPYELTRVCLQpiRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQ
.. |||  ..   . .|| |.  ..   |||| | ..    . | .| .|.|| ....||| |.  ..   |||| || |.|. ||..|.||..  . ..
qeadknrykdvgcldknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegekle

Y------FVVDPMAEYNMP---QYILREFKVTDARDG-QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKeqfgqdGPITVHCSAGVGRTGVFITL
       .|. . ....    . .... ...    | ..|.....|.||||..|||..  . .... .|.. |      ||| ||||||.||||  ....
fkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavrgsk------gPivvhCsaGiGrtGtivai

SIVLERMRY-EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
 .|...   . . || . || .| ||   .||. ||   .|  |.|. 
eyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllnyf
Phosphatase PTPRF.AA Subfamily.R_Nematode_2.PD 1664-1899 30 1.4e-43 140.7 In-house 29-260 (261) Show / Hide 
Range on Protein: 1664-1899
Range on HMM: 29-260/261
Sequence Identity: 30% (72 aa)

NKFKNRLVNIMPYELTRVCLQpiRGVEGSDyINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQ-
.| |.|  ..   . |.|        . .. | | ...   ..| .||||||| . .|||| |.  ..   ||||..  |.|||..|.| | | . .   
pkdkhRypdvPCkpetavevi--vdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldl

-YFVVDPMAEYN-MPQY-ILREFKVTDARD-GQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfgqdgPITVHCSAGVGRTGVFITLSIVLER
| .  . . . ...    | .||.|.    ..||.. .|...||..||||.     . .  |.| ..      || ||||||.|||. ||.   . ... 
grfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkksek------PivvhCsaGiGRtmafigteylare

MRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
 .  . . ...| || .|.  .||| |.    ..|| .|  
veadptieltealkelrehRwkgiqtesqlywltlgalyrl
Phosphatase PTPRF.AA Subfamily.N_Nematode_4.PD 1664-1897 31 1.5e-40 130.8 In-house 26-261 (264) Show / Hide 
Range on Protein: 1664-1897
Range on HMM: 26-261/264
Sequence Identity: 31% (77 aa)

NKFKNRLVNIMPYELTRVCLQPIRgvEGSDYINASFLDGYrQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSA----
|. |||  .|.  . ||| |.        ||| ||..     .  ||.||||| |. .||| |...   ...||| .| | |||| .|.| .        
nsdknryadilcidetrvvlknrd--pdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkf

-RYQYFVVDPMAEyNMPQYILREFKVTDAR---DGQS--RTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKeqfgQDGPITVHCSAGVGRTGVFITLS
.|.  .|. . |  . . ||. .|||      |  |    .. .|.. |..|  |..    |...  |.| |    ...|| ||||||||||  .. . .
Gkyritlvekkee-viadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkk----kekPivvhcsaGvGrtatlvGid

IVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE
   |.|  . ... . |. ||. |   ||.. |.   .   .| 
yatirirenseievldivrelramrlkavqshlqflfllvvlie
Phosphatase PTPRF.AA Subfamily.N_Nematode_6.PD 1657-1899 29 1.7e-35 114.3 In-house 17-252 (253) Show / Hide 
Range on Protein: 1657-1899
Range on HMM: 17-252/253
Sequence Identity: 29% (71 aa)

ISANLPCNKFKNRLVNIMPYELTRVCLQPirgvEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAE
..  .  .| .||  ||  .. .|. |.     .   || |....   ... .| ||.|| .. |.||.|.    .. ||||.| | |.||. .| . . 
eataflkfkdrnrytniqCcdagrlklad----dedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdk

RSA--RY-QYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfgqdgPITVHCSAGVGRTGVFITLS
    .. ..  |  ... .. . . |  |.     ...  .. ... .||. ||| .    ...  |.|.|       || ||||||||||| .. . |.
vGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk------PivvhCsaGvGrtGtlalil

IVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
|| .|     .. . .  || .|   |||| ||   .|  ||||  
iilealrlpdfqgvkdllvklreerfravqtevqylyalrcvleyl
Phosphatase PTPRF.AA Subfamily.N_Nematode_5.PD 1659-1899 26 2.6e-34 110.2 In-house 20-257 (258) Show / Hide 
Range on Protein: 1659-1899
Range on HMM: 20-257/258
Sequence Identity: 26% (64 aa)

ANLPCNKFKNRLVNIMPYELTRVclqpIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKChQYWPAER-
.   |. |||  ... .. |||    ... | ..||||| ..    .| .| || || ...||||||  ... | .|.|..|. . .. ...| |     
kafeknlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffpletg

-SARYQY-FVVDPMAEYNMPQYilREFK--VTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDfIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLS
 ..  |.    .| .  ..   |..  |    ...|  ..  ..| |... ||.  .  |.   . .... |.. |. |....|.||.| |..||.. | 
dylnlgkmfinnrkvevkedek--keytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik-raiekvlskkqgknapvvvvsdlGlgRagtfllls

IVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYL
.  .  ... ...|..|.||| .|.. .||   |.|.|.|.     
vaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldyi
Phosphatase PTPRF.AA Subfamily.R_Nematode_3.PD 1668-1889 23 2.9e-30 97.1 In-house 27-256 (267) Show / Hide 
Range on Protein: 1668-1889
Range on HMM: 27-256/267
Sequence Identity: 23% (55 aa)

NRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDgYRQQKAYIATQGPL--------AESTEDFWRMLWEHNSTIIVMLTKLRE---MGREKCHQYWPAE
.| |... .| ||| |.       .|.|.|...    ..   | ||.|.        ..  | || |  .......||| .|    . ||| .|.| .  
drrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYypek

RSA--RYQYFVVDP--MAEYNMPQYILREFKVtDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEqfgqdgPITVHCSAGVGRTGVFITL
   . . . |    ...    .   |...|    ...  |..  ....|.|...|.. . ... |  |.| |       |. ||||.|..|....    .
vdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfvekskt------pvvVHCsdGisRsatlaai

SIVLERMRYE-GVVDMFQTVKTLRTQRPAMVQTEDQYQ
. . .  . | .|. . .| || ||.  .||| ..   
elgyqliikskgkldllslikelrkqRagaiqtelela
Phosphatase PTPRF.AA Subfamily.N_Nematode_egg.PD 1639-1898 23 8.5e-24 76.0 In-house 2-255 (257) Show / Hide 
Range on Protein: 1639-1898
Range on HMM: 2-255/257
Sequence Identity: 23% (62 aa)

MELEFKLLASSKAHTSRFISANlPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML
.| .|. |  |  . |   .|.   .. | |   .   | .|| |.  ||    |.| | ...|      .| .| || .. ||||||... .   ||||
lerrfeilersvdeislttaas-dnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivml

TKLREMgrEKCHQYWPAERSARYQY----FVVDPMAEYNMPQYIlreFKVTDARD-GQSrtiRQFQFTDWPEQGVPKTGEGFIDFigQVHKTKEQFgqDG
|  .|   |.|. |||   |   ..    . .. .  .. .. .   |.||  .  |.. .| .  .  | .... .  .  .| .   .     |. |.
tsakes--erceyywpkaeseslvtvpGslrienlkvdskadpl---frvtklklvGgd---deelflehwqgdvnylsdvyspl--rvlrklrnl--sk

PITVHCSAGVGRTGVFITLSIVLERMRYEGVV--DMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
.  || ........ | | ..    ..   . ..|. || .|.  |..  .| . ||  | .     
pvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlff
Phosphatase PTPRF.AA Subfamily.N_Fungi_PTP1.PD 1666-1755 34 8.5e-24 75.8 In-house 47-150 (343) Show / Hide 
Range on Protein: 1666-1755
Range on HMM: 47-150/343
Sequence Identity: 34% (35 aa)

FKNRLVNIMPYELTRVCLQ----P----IRGVEGSDYINASFLDGY----RQQKA--YIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQ
||| .||.||| .|| |.    .       ....|||||..|       ...    |||||.|| .  .||.... . . ..|..||.. |...|||..|
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr

YWPA
|.  
YWqe
Phosphatase PTPRF.AA Subfamily.N_Fungi_PTP1.PD 1786-1898 29 1.6e-16 51.8 In-house 206-341 (343) Show / Hide 
Range on Protein: 1786-1898
Range on HMM: 206-341/343
Sequence Identity: 29% (37 aa)

DARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIG--------QVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLE----------RMR----YEG
.|  ..  .. |.|.  |.. ..    | ..  .          . ..  .  .  || |||||||||||...||  .|...|       . | ....|.
taavsepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaak

VVD-MFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY
 || ||  |||. ||.  .| |.| |          
trDlisiivnelrkqrismvqnldqfifiYeallfy
Phosphatase PTPRF.AA Subfamily.N_Nematode_eak.PD 1666-1818 26 1.2e-14 45.9 In-house 28-178 (281) Show / Hide 
Range on Protein: 1666-1818
Range on HMM: 28-178/281
Sequence Identity: 26% (40 aa)

FKNRLVNIMPYELTRVCLQPIRgVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERsARYQYFV
.||.|.|.|..   | | . .  .   ||||| ..     . || |  .  .    ||.|. | .|  ||.| .  |..||  .|.| .    ..| ..|
nrnrvvkivpqdrylvrltssq-lnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdkt-evlkyGi

VDP-MAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTgEGFIDF
    || . . ||.  ..   .  ..  .  ...  | |  .||  | |. .  
ldverkeyavkrniletrllilrkGnethrvlhykvfGwtettlpky-edflal
Phosphatase PTPRF.AA Subfamily.PTPDC1.PD 1828-1891 35 2.8e-10 31.7 In-house 162-220 (229) Show / Hide 
Range on Protein: 1828-1891
Range on HMM: 162-220/229
Sequence Identity: 35% (23 aa)

QFGQDGPITVHCSAGVGRTGVFITLSIVlermrYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLC
.  ..| |.||| || ||||| |.  .|     |   ..  . .|..| .||  .|| .| .|.
faleegkiavHCHAGlGRtGvliacylv-----yakrltaeeaiklvrskrpksiqtreqvelv
Phosphatase PTPRF.AA Family.DSP.PD 1729-1889 15 2e-08 25.6 In-house 130-237 (387) Show / Hide 
Range on Protein: 1729-1889
Range on HMM: 130-237/387
Sequence Identity: 15% (26 aa)

EHNSTIIVMLTklremgrekchqywpaersaryqyfvvdpmaeY------NmpqyilrefkvtdardgqSRTIRQFQFtDWPEQGVPKTGE---GFIDFI
|.. | || ||                                .      .                  .  |.  ..  ..  ..|.  ..|||| ...
elgvtkivnlt--------------------------------ddkpqftk------------------elgikylri-pidDhnapplenlfekaidfi

GQVHKtkeqfgQDGPITVHCSAGVGRTGVFITLSIVLE-RMRYEgvvdmfQTVKTLRTQRPAMVQTEDQYQ
.      . | . ||| ||.||.|. |   ..   .. .|      .... .| .|| ... ....     
eegnd------skgvVlVHCkaGkgRsgtliiaYlmksegltle------ealdwvrskRpgvitpnqgfl
Phosphatase PTPRF.AA Subfamily.PRL.PD 1821-1870 30 2.3e-07 22.3 In-house 70-119 (140) Show / Hide 
Range on Protein: 1821-1870
Range on HMM: 70-119/140
Sequence Identity: 30% (15 aa)

QVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQT
.. |.| .  ..  ..||| ||.||. |...|... . |.||  |.. ..
ellkekfkeepkstvavhcvaGlGraPvlvalalieaGmkyedavefire
Phosphatase PTPRF.AA Subfamily.DSP23.PD 1826-1891 24 1.4e-06 20.1 In-house 60-120 (128) Show / Hide 
Range on Protein: 1826-1891
Range on HMM: 60-120/128
Sequence Identity: 24% (16 aa)

KEQFGQDGPITVHCSAGVGRTGVFITLSIVLERmryeGvVDMFQTVKTLRTQRPAMVQTEDQYQLC
.|   ......|||  |.|||| ...  .| |.    | .   ...  .| .|.  ..| .| .. 
eeaekkeeavgvhcalGlGrtGtllacylvkee----g-laaddaiaevrkrrkGsietveqekav
Phosphatase PTPRF.AA Subfamily.CDC14.PD 1832-1889 35 2.1e-06 19.2 In-house 198-250 (258) Show / Hide 
Range on Protein: 1832-1889
Range on HMM: 198-250/258
Sequence Identity: 35% (20 aa)

DGPITVHCSAGVGRTGVFITLSIVlERMRYegvvDMFQTVKTLRTQRPAMVQTEDQYQ
.| | ||| ||.||||..|.  ..  . |.       .|.  ||  || .| .  |  
eGaiavhCkaGLGrtgtligcyli-khyrf----taaetiawlriarPGsvigpqqty
Phosphatase PTPRF.AA Subfamily.DSP19.PD 1795-1880 19 6.4e-06 17.7 In-house 48-122 (139) Show / Hide 
Range on Protein: 1795-1880
Range on HMM: 48-122/139
Sequence Identity: 19% (17 aa)

IRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKeqfgqdGPITVHCSAGVGRTGVfITLSIVLERMRyegvVDMFQTVKTLRTQRPA
. . .  | ||. . .  .  .||| ......      | . |||.||| |.   . .. .... .    ... ......|..||.
yksieilDlpetkllsylkealdFieearskd------grvlvHCnAGvSRsas-vviaylmkdee----lslekalekvrearpc
Sequence
Name Sequence Type Origin Length Description Download
PTPRF.AA Protein None 1907 None Fasta, JSON
PTPRF.NA RNA None 5721 None Fasta, JSON
PTPRF.AA.PD1_1351-1609 Protein Phosphatase Domain None 259 None Fasta, JSON
PTPRF.AA.PD2_1638-1900 Protein Phosphatase Domain None 263 None Fasta, JSON