PTPRU
Species: Human
Alias: PTPRU, R-PTP-PSI, PTP-J, GLEPP1, PTPPSI, PTPU2, PCP-2, FMI, PTPRO, FLJ37530, hPTP-J, PTP-PI, PTP
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RK
Protein domain

Protein domains of PTPRU.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
MAM PTPRU.AA MAM 22-188 36 8.4e-75 255.74 SMART 1-192 (192) Show / Hide
Range on Protein: 22-188
Range on HMM: 1-192/192
Sequence Identity: 36% (71 aa)

TPAAGCTFEEASDPAVPCEYSQAQYDD--FQWEQVRIHP---------GTRAPADLPHG--SYLMVNTSQHAP-GQRAHVIFQSLSEN-DTHCVQFSYFL
| ...|.||...| ...| ..|...||  |.||.|. |.         |.. .  ...|  .|....||...| ||.|. |...|..| |.||.||.|..
TSCGNCDFEWGND-HTMCGWHQDWWDDTGFHWEWVSSHTFNHYAMSHDGPHRDHTMGNGSGHYMYFETSMGKPGGQTARLISPPLYPNRDQHCLQFWYHM

YSRDGHSPGT-LGVYVR-VNGGPLGS----AVWNMTGSHGRQWHQAELAVST-FWPNEYQVLFEALIS-PDRRGYMGLDDILLLSYP---CAK
|.|.| ..|| | |||| .|..|...    ..||..| .||||||||....| ||....||.||....   ..||..||||.....|   | |
YHRKGSHTGTKLCVYVRYENNHPQDMWNNCLIWNRHGHQGRQWHQAEVTIHTGFWQQPFQVVFEGWRGSQWHCGYIALDDINFWNHPHENCWK

MAM PTPRU.AA MAM 27-188 32 5.8e-60 210.33 Pfam 1-175 (175) Show / Hide
Range on Protein: 27-188
Range on HMM: 1-175/175
Sequence Identity: 32% (58 aa)

CTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPG--TRAPADLPH-------GSYLMVNTSQH-APGQRAHVIFQSL-SENDTHC-VQFSYFLYSRDGHSP
|.|| . |.   |...| . |||.|....   .       . .|       |.|..|.|| | ..||.|. . ... .....|| .|| |..|... | |
CDFE-DEDG-NLCGWTQDWTDDFDWTRQSGPTPHTHYTGPWMDHTHGGQCSGHYMYVETS-HQQEGQTARLLSPWFYPPRGPHCCLQFWYHMYGSHVH-P

GTLGVYVRVN--GGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLDDILLLSY---PCAK
||| ||||.|  .|. . ..|...|..|..|.||......|||...||.||. .....||....|||.|...   || .
GTLNVYVRENDNQGGWQTPLWSRSGNQGNSWQQAHVTLNQFWPQPFQVVFEGVRGRGWRGDIAIDDISLSEGIMEPCPE

Fn3 PTPRU.AA FN3 488-576 18 1.2e-10 42.62 SMART 1-69 (69) Show / Hide
Range on Protein: 488-576
Range on HMM: 1-69/69
Sequence Identity: 18% (19 aa)

GIAAES---LTFTPLED-------MIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLHPG----TTYLFSVRARTG-
  . .    |..|.  .        . |.|..|      |..|.                              .....|.||    |.| |.|||..| 
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR------------------------------YTVTGLKPGQYPWTEYEFRVRAVNGN

-KGFG
 .| |
DAGEG

Phosphatase PTPRU.AA Subfamily.RK.PD 893-1145 50 6.7e-124 403.8 In-house 1-266 (267) Show / Hide
Range on Protein: 893-1145
Range on HMM: 1-266/267
Sequence Identity: 50% (134 aa)

GFKQEYESF----FEG----WDATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDpNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSI
..|.|.|..    .|.    .|..||... . .|.... ||||..|.|... || ..|||||..||.|.|...||.||||..|.|.||||.|..|.|.||
qlkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasi

VMITKL-VEVGRVKCSRYWPEDSDT-YGDIKIMLVKTETLAEYVVRTFALER--RGYSARHEVRQFHFTAWPEH-GVPYHATGLLAFIRRVKASTPP-DA
||.|.| ||||||||..|||||... |||||..||..|..|..|||.|..|.  ||.....|||||.|..|||. .||.....||..|||||.|... ..
vmlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeee

GPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEAC
|.||.||.||.||.|..|..|..|.|.|.|||||..|.||||..|.|||..|||||.|..|.||||.
GrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal

Phosphatase PTPRU.AA Y_phosphatase 913-1143 46 2.2e-119 407.72 Pfam 1-243 (243) Show / Hide
Range on Protein: 913-1143
Range on HMM: 1-243/243
Sequence Identity: 46% (113 aa)

KVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDG-YHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGR-VK-CSRYWPE----D
  .  |    |.||. ||||.|. ||.. |||||||||| |.... .|.||||.|. . ||||||||..|..|||.....| || .| |..|||.    .
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

SDTYGDIKIMLVKTETLAEYVVRTFALERRGY--SARHEVRQFHFTAWPEHGVPYH-ATGLLAFIRRVKASTP-PDAG--PIVIHCSAGTGRTGCYIVLD
. ||||... .|..|....|.|||| ..  |   . ...|...|.|.||.|||| . ....| |||.|. ..| ||.|  |||.||||| ||||.....|
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAID

VMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE
.|... |.||.|||...||.... | .|.||||||||....|||
IMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase PTPRU.AA PTPc 893-1146 35 1.9e-110 374.17 SMART 1-308 (308) Show / Hide
Range on Protein: 893-1146
Range on HMM: 1-308/308
Sequence Identity: 35% (111 aa)

GFKQEYESFFEGWDATKKK------DKVKGSRQE-----------PMPAYDRHRVKLHPMLGD----PNADYINANYIDGYHRSNHFIATQGPKPEMVYD
||..|.|.  .     ...      ..  . ..|             |.||. ||||.|  |.    .. |||||||||||.|.. .|.||||.|. . |
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMVWQEHCSSIVMITKLVEV--------GRVKCSRYWPEDSDTYGDIKIMLVKTETLA-EYVVRTFALERRGY--------SARHEVRQFHFTAWPEH
|||||||..|..|||.....|         ||.|| .|||... |||.|.. ....|... .|..||| ..  |         |  ..|...|.|.||.|
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDEPMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPDH

GVPYHATGLLAFIRRVKASTPPD-------------------AGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYI
||| .....|.|||.|... .                     .||||.||||| ||||.....|.|... |.   |||...||.. . | .|.|||||||
GVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQYI

FIHDAILEACL
|....||| ..
FCYRCILEYIK

Phosphatase PTPRU.AA Subfamily.R_Anemone_2.PD 909-1144 45 4.1e-91 296.6 In-house 24-260 (262) Show / Hide
Range on Protein: 909-1144
Range on HMM: 24-260/262
Sequence Identity: 45% (108 aa)

KKKDKVKgSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPED-SD
.. .| |  |   . |||. ||||... |....|||||||||||.|.. .||||.| || . |||||||. ... |||.|...| |..|. ||||.. | 
epvnkak-nryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWPskgsr

TYGDIKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKAST-PPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAE
.||.... | .. .|..||.|.| ..| . ..  .|||||.|.||..||| ....||...|.|.....|||||.||||| |||| .|..|..|. .. |.
sygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiavdillerik

CEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
.||... ||.| ..|  |.||..||.||.|..|||   
aealvdvfqtvkqlreqrnlmvqtkdqyefiydvllea

Phosphatase PTPRU.AA Subfamily.R_Anemone_1.PD 903-1144 45 1e-89 292.0 In-house 15-256 (258) Show / Hide
Range on Protein: 903-1144
Range on HMM: 15-256/258
Sequence Identity: 45% (110 aa)

EGWDATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYW
| .....|..  |  |.. . |.| .|| |. . .|...||||| |........ |||||.| .| | |||||||||....|||.| |.|.   ||..||
eekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnliegekkkchqYw

PEDSDTYGDIKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVML
|. ...||.... | |.|. |.|..||..|.... . ..||.|.||| ||..||| .|| .|.. |.|..|  ..| |.|.||||| |||| ..|.| ||
PdstekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaGvgRtGaflvidaml

DMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
. |  | ||||.| ||.. . | .|.||.|||.||| |.|||
eqakkekvvDifnyvkairedrphmvqtkeqyvfihlavlea

Phosphatase PTPRU.AA Subfamily.RB.PD 916-1144 48 4e-85 276.8 In-house 29-259 (261) Show / Hide
Range on Protein: 916-1144
Range on HMM: 29-259/261
Sequence Identity: 48% (109 aa)

GSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDS--DTYGDIK
| . . .||  ||||. .  ....||||||||.||.  ...|||||| || | |||||||....| |||.|.||| |..|| .|||.|..|||||. |..
knrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYWPadeepvlyGdik

IMLVKTETLAEYVVRTFALERrgYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPD--AGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVV
...| |.|.|.|..|.   . ...|||.|||.||.|||| ... ||.|.|.|. ..  .  ..|||.||||| |||| .| || .|.  | . .||..  
vtllaekeldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrllqaieendyv

DIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
|  | ..|....|||.||||||...|.      
dvfgvvaelReeRnllvqtekqyifiheclldl

Phosphatase PTPRU.AA Subfamily.RA.PD 908-1143 43 5.7e-81 263.2 In-house 22-263 (266) Show / Hide
Range on Protein: 908-1143
Range on HMM: 22-263/266
Sequence Identity: 43% (104 aa)

TKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPED-S
..|..  | .|   .  ||  || |  . | ...||||| .||||.. ..|||.|||| | | |||||.|. ....|||.|.| | .. ||.|||.. . 
ankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqywpdeGl

DTYGDIKIMLVKTETLAEYVVRTFALERRGYSA----RHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAG-PIVIHCSAGTGRTGCYIVLDVM
|||.|.. . ... | .| || | ... . ..       |||||||.||| ||| .. |.| ....||.  .  |. |||.|||||.|||| .|||| .|
vtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtfivldav

LDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE
.. ..|...|... ||.|  .| .|.||.||| ||. ..|| 
lervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle

Phosphatase PTPRU.AA Subfamily.R_Sponge_2.PD 907-1144 43 9.6e-81 262.5 In-house 19-260 (262) Show / Hide
Range on Protein: 907-1144
Range on HMM: 19-260/262
Sequence Identity: 43% (106 aa)

ATKKKDKVKGSRQEPMPAYDRHRVKLHPmLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPED-
..|.|. |  .| . . .|| .||.|..  | ...|||||...|||.| . .|||||| .| | |||||||  . |.|||.|.|.| |. || .||||  
iaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPekv

--SDTYGDIKIMLVKTETLAEYVVRTFALER-RGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRV-KASTPPDAGPIVIHCSAGTGRTGCYIVLDVM
  ...||..|. |...|.||.|..|.. | . .. . ...|.||||.|||||.|| .|| ||..|.||.| .    ..|...||.| |||| .|.||..|
deeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfialdsv

LDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
.  . |...|... .||| ..|. ..|...|| |||||.||. 
lerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalley

Phosphatase PTPRU.AA Subfamily.RG.PD 907-1144 42 5.3e-80 260.1 In-house 22-262 (264) Show / Hide
Range on Protein: 907-1144
Range on HMM: 22-262/264
Sequence Identity: 42% (103 aa)

ATKKKDKVKgSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPE--
..|...| |  |.  . |..| ||||.|. |  . |||||.|||||.||...|.|||| .| . |||||.|... . |||.|.|.| || ...|||.  .
skkeenkek-nReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrdedvyWPkkd

DSDTYGDIKIMLVKTETLAEYVVRTFALERRGYSARHE--VRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVML
. .....|. |...|.|..|.||.| |. .     .|  |||.|.| ||..|.| ...  | |... .|... .|||||.|.|||.||.| ||.|| .| 
eplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivvhdsaGvgragtyialdtll

DMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
  | |  |..|...|.. ..| ....|||||.||.||.||. 
qqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel

Phosphatase PTPRU.AA Subfamily.N_Choan_1.PD 893-1144 41 4.6e-77 250.4 In-house 1-260 (262) Show / Hide
Range on Protein: 893-1144
Range on HMM: 1-260/262
Sequence Identity: 41% (109 aa)

GFKQEYESFFE-G----WDATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMI
||..|||.. | |      |.|... |.  | . . |||  |||..|   . |.||||||...||.  ...|||||| |. ...||.|||... | |||.
GfieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmv

TKLVEVGRVKCSRYWPEDS--DTYGDIKIMLVKTETLAEYVVRTFALERRGYSARhEVRQFHFTAWPEHGVPYHATGLLAFIRRV-KASTPPDAGPIVIH
|. .| |..|| ||||...   ..||...  ...|. ..|. |.| |||..  .| ||.|...||||.||||  .. || | . | ||...    |.|||
treieagklkChryWPdenselklgdvtvkslseeekktyierkfkleresgetr-eveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvih

CSAGTGRTGCYIVLDVMLDMAECEG-VVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
|||| ||||.|| || ... .| .  ..|. . |. |  .|  |.||  || |..|.|.| 
CsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavlda

Phosphatase PTPRU.AA Subfamily.N9.PD 907-1143 43 4.1e-71 231.1 In-house 20-272 (275) Show / Hide
Range on Protein: 907-1143
Range on HMM: 20-272/275
Sequence Identity: 43% (102 aa)

ATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---
|.|..  ..  | . .  ||. ||||  . .|...||||||..|||.. . ||||||| .. | |||||||....  |||.|..|| ||.||..|||   
asklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywplee

EDSDTYGDIKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKA-------------STPPDAGPIVIHCSAGTG
|.|. .||...  |..|.  .|.||.. ...   .   .|  | |..||..|||  |. || ....|....  |||.||||| |||| .| ||. |.  |
essaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiG

RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE
 .|.||. ..||.| ..|  .|||.||| | . |.||                
rtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle

Phosphatase PTPRU.AA Subfamily.R_Ecdysozoa.PD 907-1143 37 1.9e-70 228.5 In-house 22-266 (269) Show / Hide
Range on Protein: 907-1143
Range on HMM: 22-266/269
Sequence Identity: 37% (92 aa)

ATKKKDKVKgSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVkCSRYWP-ED
. || ...|  | | . |.|..||||... |. ..|||||..| ||. ...||| |.|  . . |||||... .   |||...| |  |  |..||| ||
sekkenalk-nryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknrk-cakyWpied

SDTYGDIKIMLVKTETLAEYVVRTFALERRG---YSARHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKASTPPD-----AGPIVIHCSAGTGRTGCYI
   |||| . ||..|.  .|. |.. . . .     ....| |...|.|. .  || .|.||| .|..|.     .      .|||.|||||.||.| ..
evqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgrsgifv

VLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE
 ||..|.  . |  |||.. || | |.|  ..|  |||.|.. |...
aldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralad

Phosphatase PTPRU.AA Subfamily.N12.PD 902-1145 35 2.6e-68 221.5 In-house 22-269 (270) Show / Hide
Range on Protein: 902-1145
Range on HMM: 22-269/270
Sequence Identity: 35% (88 aa)

FEGWDATKKKDkVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRY
..   ..|... ||  |   .  ||  ||.|. . .... ||||||.| | . . ..||.||| |. . |||||.|. . . .||. ..||.|. || ||
ysteagekeen-vkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCery

WPED---SDTYGDIKIMLVKTETLA-EYVVRTFALERRgySARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIV
|||    . ..|.... | . ...  ....||...|..  .....|.|||.||||.||||  |. ||..|. |.     ..|.|.||||| ||||  |..
WpeegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiia

LDVMLDMAECEGV---VDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEAC
| . .. . | .   .|... | .|  .|. ..||.||| ... |..| . 
idyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv

Phosphatase PTPRU.AA Subfamily.N3.PD 907-1144 37 5.5e-67 217.1 In-house 20-259 (261) Show / Hide
Range on Protein: 907-1144
Range on HMM: 20-259/261
Sequence Identity: 37% (92 aa)

ATKKKDKVKGSRQEPMPAYDRHRVKLHpmlgDPNADYINANYID----GYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYW
|..| . ..  |   . .||  ||||.    . ..|||||||..    . . .|..|||||| .. . |||.|||..... |||.| ||| ||||| .||
aarkpenlaknryrdilpydatrvklk----esetdyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqyW

PEDSD--TYGDIKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDV
|| .|  ..|...... |...  .||.| . |...  . .... |. ..|||.|||| ... .| |..||..    .  |.|.||||| |||| .|.|..
PetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlillet

MLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
 | . |..  | . . |.|.  .| ...||..|| |. .|||.|
alalieaaepvypldivrtmrdqramlvqtvsqykfvCeailka

Phosphatase PTPRU.AA Subfamily.N6.PD 896-1142 38 5.7e-66 214.2 In-house 24-291 (295) Show / Hide
Range on Protein: 896-1142
Range on HMM: 24-291/295
Sequence Identity: 38% (102 aa)

QEYESFFEGWDATKKKDKVKGSRQEPMPAyDRHRVKLHPM-LGDPNADYINANYID--------GYHR-----SNHFIATQGPKPEMVYDFWRMVWQEHC
|| |. ..  ...| ..| |   .. .|. |  ||.|.      | .||||||||.        | .       ...|||||. .. | ||||||||| .
qeseklysrkegekienkeknryknilPf-DhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFWrmvwqens

SSIVMITKLVEVGRVKCSRYWPED--SDTYGDIKIMLVKTETLAEYVVRTFALERR-GYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKAST--PP
  |||.|| || |. ||.||||.   ....|.|... .. .. |.|..|.| ....   .  .|..|.||.|||.|||| ...| |.. |.. .    .|
rvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeele

DAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGV---VDIYNCVKTLCSRRVNMIQTEEQYIFIHDAIL
||||.||||| |||| .||.|..|.. | .|.   .||.. .|.. | | ...|||.||.|.  |.   
kagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq

Phosphatase PTPRU.AA Subfamily.N5_RR.PD 926-1142 38 1.5e-63 206.0 In-house 36-261 (265) Show / Hide
Range on Protein: 926-1142
Range on HMM: 36-261/265
Sequence Identity: 38% (86 aa)

DRHRVKLHPMLGD-PNADYINANYIDGYHR-SNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDT-----YGDIKIMLVK
.. || |..  .. ....||||||| ||.. |. ..||||| |. . |||||..||... |||.||| |  | ||..|.|.. |.|||..|  ... .  
ensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeiserygdveikvee

TETLAEYVVRTFALERRGYsARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTP---PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYN
.| ||.. |.      ...|  . .|.||.| .| ... || ... |. |       ..|.|.||||| |||||.|  .. .   . |.|||. . |  |
iverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlk

CVKTLCSRRVNMIQTEEQYIFIHDAIL
   |  |.||.||| .|| |.      
ivcnlrldrGGmvqtseqyelihralc

Phosphatase PTPRU.AA Subfamily.RC.PD 937-1143 35 1.5e-63 206.1 In-house 69-285 (288) Show / Hide
Range on Protein: 937-1143
Range on HMM: 69-285/288
Sequence Identity: 35% (76 aa)

GDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDTYGDIKIMLVKTETLAEYVVRTFALERRG
..  ..|||| .||.|.. . .||.|||. | | |||||....    |||.|.| |  | ||..|| |   .|||... | .|.  ..|..|. | ..  
seegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrekcaeyweeGkrayGdvevdlkdtdkssdyilrklelvnkk

YSARHEVRQFHFTAWPEHGVPYHATGLLAFI----------RRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVN
 .  || |. .|.|.....| .   || .|          |...|     ..|...||..|..||| .| |. .|. .|.| .||... || |  .|  |
rkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarpl

MIQTEEQYIFIHDAILE
...|||||...|.. | 
mvsveeqyillydvlve

Phosphatase PTPRU.AA Subfamily.N13.PD 907-1144 39 6.9e-63 204.0 In-house 20-257 (259) Show / Hide
Range on Protein: 907-1144
Range on HMM: 20-257/259
Sequence Identity: 39% (96 aa)

ATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGdpnadYINANYIDGYHRS--NHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPE
.|||.. .  |   .  ||. ||||    |     ||||..|         ..||.||| || | |||.|||. ... |.|.|. .| |.||| ||||| 
vgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPe

DSD----TYGDIKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPpDAGPIVIHCSAGTGRTGCYIVLDV
 .     .. ... |.|.. | ..|||..|..    .. .|| ...|..||.|||| .|. |. |...|.     ||||||.||||| ||.| .|..||.
rknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPivvhcsaGiGrsGvlitidv

MLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
|.. | .  .|. . |..|  .|  ..||..||||.. ||||. 
vlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailev

Phosphatase PTPRU.AA Subfamily.N_Choan_2.PD 927-1145 34 1e-59 193.3 In-house 35-265 (266) Show / Hide
Range on Protein: 927-1145
Range on HMM: 35-265/266
Sequence Identity: 34% (78 aa)

RHRVKLHPMLGDPNADYINANYIDGYHR-SNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDTY-----GDIKIMLVKTE
. ||.|...  |... ||||||. |..  ....||..||.|  . .||||.|.|. ..|||.|.|.| || ||.||||.....|.||.. ...|    |.
atRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkladgkikvlalsee

TLAEYVVRTFALERrgYSARHEVRQFHFTAWPEHGVPYHAT------GLLAFIRRVKASTP--PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVD
..   ||.   .  .... |....||.|||| ..        ||. .| |....    .|.|...||||| ||||. |..| .. . | .. ||. . ..
keegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDiavrlLeetkkvd

IYNCVKTLCSRRVNMIQTEEQYIFIHDAILEAC
 |   |....|. ||| ... |..| .      
vlaiieelRkdRmalvqhpeqyellykavveya

Phosphatase PTPRU.AA Subfamily.RN.PD 898-1143 38 1.9e-54 176.1 In-house 12-261 (264) Show / Hide
Range on Protein: 898-1143
Range on HMM: 12-261/264
Sequence Identity: 38% (95 aa)

YESFFEGWDATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYI-DGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRV
||.  .  ...|... ||  |.. . .||  ||||.    . . |||||  | |   |.  .|||||| .. . |||.|||.. .  ||..|.| | |  
yeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvk

KCSRYWPED-SDTYGDIKIMLVKTETLA-EYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGC
.|.||||.. |..|.  .. ||     . .|.||.| |     |    | |||| .|||.|||  |  || | |.|  |    .|||.|||.|.||||.|
qckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGv

YIVLDVMLD-MAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE
|..|..|. ..     .||   .. |  .| ....|..|. |.  |. | 
yilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae

Phosphatase PTPRU.AA Subfamily.N23.PD 920-1144 34 6.9e-54 174.6 In-house 109-348 (350) Show / Hide
Range on Protein: 920-1144
Range on HMM: 109-348/350
Sequence Identity: 34% (82 aa)

EPMPAYDRHRVKLH-PMLGDPNADYINANYIDGY-HRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSD---TYGDIKI
.|    |. ||||.       . ||||| |.      | .|||||||... . ||| |||... | |||.|| || .. || .|||.| ...||... | 
tpdsrhdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrv

MLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKAST----PPD-----AGPIVIHCSAGTGRTGCY-IVLDVMLDM
....  ... |.. |. .  |. ..| ..|.|.|.|.|||     ||||.  |..        .       ||..||||| |||| . .|  .. .. . 
slkslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysairel

AECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
.|...| . |..|.  | .|.|..... .. .|.|||   
tagngiiniprvvrrlrqqRkymvqkkvilkklyeavlea

Phosphatase PTPRU.AA Subfamily.N_Nematode_1.PD 906-1144 33 1.3e-49 160.3 In-house 19-263 (265) Show / Hide
Range on Protein: 906-1144
Range on HMM: 19-263/265
Sequence Identity: 33% (84 aa)

DATKKKDKVKGSRQEPMPAYDRHRVKL-HPMLgdpNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPE
.| |.... .  | . ..  |. |||| .. |    .||| |||.    ....|| .|.|. . ..||| || ||.  .|||. ||.| |..||. |.| 
kafkeaqeadknrykdvgcldknrvklaeepl---psdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpa

DSD---TYGDI--KIML-----VKTETLAEYVVRTFAL--ERRGYsARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTppdaGPIVIHCSAGTGRT
 ..   .. .   ||..     ||. . .| |...  |  |  |    ..|.....| ||..|||    . | .. .|..|.    ||||.||||| |||
kegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGe-ktrkvthyqWtdWPdrGvPpadlaalelleavrgsk----gPivvhCsaGiGrt

GCYIVLDVMLD-MAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
|  .... .|| ..| . . |. . || ....| . |||. ||.|.|  .|. 
Gtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllny

Phosphatase PTPRU.AA Subfamily.N1.PD 912-1144 34 2.1e-48 156.5 In-house 26-266 (268) Show / Hide
Range on Protein: 912-1144
Range on HMM: 26-266/268
Sequence Identity: 34% (84 aa)

DKVKG-SRQEPMPAYDRHRVKLHpmlgDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDT--
.. .|  |   .  ||  |.||.    . . |||||. ..  .   ..| |||| |. .  ||.|||.... ...|. |.|| ...||  |||.....  
penrglnryrdvspydhsrikle----radvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqeeeeae

--YGD--IKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKAST--PPDAGPIVIHCSAGTGRTGCYIVLDVML
  . .  .|. |...|.  ...||.. ||    .  .|. .||.| ||. |||   . .| |. .|. |    .| ||.||||||| ||.| . ..| .|
llleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtlslvdtcl

DMAECEGV---VDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEA
   | .|    ||| . .  | . || .||| .|  |   |||| 
veiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaileg

Phosphatase PTPRU.AA Subfamily.N14.PD 908-1142 28 3.5e-47 152.3 In-house 21-271 (275) Show / Hide
Range on Protein: 908-1142
Range on HMM: 21-271/275
Sequence Identity: 28% (70 aa)

TKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDpNADYINANYIDGYH--RSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPED
.| .. .. .| . .  |.  ||.| |   . . .||||  |      .. ..|..||| .. | |||.|||... . |||.|.  | |.|. .|.|.. 
aklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeksfkylPkl

-----SDTYGDIKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKA-----ST--P---PDAGPIVIHCSAGTG
    . ..|  |..   .|.   .. ... |.    . . .|  . .| ||.||||   .|.| |...|..     ..  .|...||||| ||||  |. 
eskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvG

RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAIL
|...   |.. ..|| . ...|  .|  ..||  || |......        
rtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvli

Phosphatase PTPRU.AA Subfamily.N20.PD 920-1144 36 5.9e-43 138.7 In-house 33-255 (257) Show / Hide
Range on Protein: 920-1144
Range on HMM: 33-255/257
Sequence Identity: 36% (80 aa)

EPMPAYDRHRVKLhpmlGDpNADYINANYIDGYH--RSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDTYGDI---KI
.  ||  || |    |  . |||||.||          .||||||    . |||.|| .. .  | |||. .| | .|| .|||..   ...| . . | 
rdilpydstrvpl----gk-skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkkplelkhfrv

MLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTppDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIY
 ...| | .  .   . | |.|..|| ||.|| |  |  .. .||  . |    .||.|.||||| |||| ....||..     .  ..| . |  .  .
flenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarksh--ltgpmvvhcsagigrtgvflcvdvvfcaivkncsfnim

NCVKTLCSRRVNMIQTEEQYIFIHDAILEA
|  |.||.||| | .| .||          
divaqmreqrsgmvqtkeqyhfcydivlev

Phosphatase PTPRU.AA PTPc_motif 1042-1143 42 4.6e-42 146.98 SMART 1-92 (92) Show / Hide
Range on Protein: 1042-1143
Range on HMM: 1-92/92
Sequence Identity: 42% (46 aa)

EVRQFHFTAWPEH-----GVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIF
.|...|.|.||.|     |||.   ..| |||.|..       |||.||||| ||||.....|.|...      |||...|| . . | .|.||||||||
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIF

IHDAILE
....|||
CYRCILE

Phosphatase PTPRU.AA Subfamily.N_Nematode_4.PD 917-1143 28 2.1e-41 133.4 In-house 30-261 (264) Show / Hide
Range on Protein: 917-1143
Range on HMM: 30-261/264
Sequence Identity: 28% (67 aa)

SRQEPMPAYDRHRVKLHPMlgDPNADYINANYIDGYhRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDT---YGDIK
.| . .   |  || |.    ||. ||| |...       ..|.|||| .| . ||| ||..| .. .||. .|.| |  ||.||.||.|..   .|. .
nryadilcidetrvvlknr--dpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkfGkyr

IMLVKT--ETLAEYVVRTFALERRG----Y-SARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKAstPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAE
| ||..  |..|. ..... .          | .  |. .... |...  |  |. .. ... ||   ..  .|||.||||| |||  .. .|    .  
itlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrtatlvGidyatirir

CEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE
  . ... . |. | . |.. .|.. |..|.   ..|
enseievldivrelramrlkavqshlqflfllvvlie

Phosphatase PTPRU.AA Subfamily.R_Nematode_2.PD 917-1140 30 2.1e-38 123.5 In-house 33-255 (261) Show / Hide
Range on Protein: 917-1140
Range on HMM: 33-255/261
Sequence Identity: 30% (69 aa)

SRQEPMPAYDRHRVKLhpMLGDPNADyINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDTYGDI---K
| . .|  .. .|.   .  .  .. | ||...   . ..|||||||  . ..||| || ||..  |||... ||  . ||..|.| .     |.   .|
hRypdvPCkpetavev--ivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgrfs

IMLVKTETLAEYV--VRTFALER-RGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTppdaGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGV
  |..|....    .||.  |   |  | . |. . .. ||..|||   . |   .  || |.|||.||||| |||. .|  ... .  | .  . . . 
iktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelfeLlelvkkse----kPivvhCsaGiGRtmafigteylareveadpt

VDIYNCVKTLCSRRVNMIQTEEQYIFIHDA
.| | . | . ||||.|. ... .      
ieltealkelrehRwkgiqtesqlywltlg

Phosphatase PTPRU.AA Subfamily.N6.PD 1168-1440 26 1.5e-36 117.6 In-house 6-294 (295) Show / Hide
Range on Protein: 1168-1440
Range on HMM: 6-294/295
Sequence Identity: 26% (75 aa)

DPQSNSSQLREEFQTLNSVTpPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTD--GDSNNYINAALTD---------SYTR----SAAFIVTLH
|.|..  . |||..|.      .  ... .  ..|..|||  ..|| |     |  ..     ..||||   .         . .. .|.|  .|..| .
rpksqtlgfweefeelqkqe-seklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqg

PLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAwPCLQYWPEPGRQ-QYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHlLVRHFQFLRWSAyRDTP
||||.|..  .. |||. . .. .    | .|||. ... ..| ..|. .| .. .| . | | |.. .  .| ......|  |    ..| .....|..
cLkdtvsdFWrmvwqensrvivmttkevergkn-kCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkear-eifqyhfkaWPd-hgvp

DSKKAFLHLLAEVDKWQAES-GDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNL---VDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
| .|.| | |    | ..||| .| || |||    .||..|. . |   .|.  . |..|... ..|| .||.| | ..  |.          
kdpgvvlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqfyi

Phosphatase PTPRU.AA Subfamily.N_Nematode_5.PD 912-1142 24 8.6e-36 114.9 In-house 24-254 (258) Show / Hide
Range on Protein: 912-1142
Range on HMM: 24-254/258
Sequence Identity: 24% (57 aa)

DKVKGSRQEPMPAYDRHRVklhpMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCsRYWPEDSDTYGD
.| .|.. .. .|  ||    .|.|.. .||||..|.  . ....| || |.|. . |||||| ||.. |.|....  |.. ..  ..|. ...|  .. 
knlkknrskdvkilDetrV----kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffpletgdyln

IKIMLVKTETLAEYVVR--TFALE--RRGYSARHEVRQFHFTAWPEHGVPYHATGLLA-FIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDVMLDMAE
|.... .  .       . .|    | |  . ..  |.| |... || . . ...  | .|..  .  |.|.....|.||.|  ..|.|. .  . .  .
lgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqln

CEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAIL
.| ...|.. | |......  || ... |.|     
ngkepnideilkkirsqRpgavesliqyasvyaavl

Phosphatase PTPRU.AA Subfamily.N_Nematode_6.PD 917-1143 27 5e-35 112.6 In-house 28-250 (253) Show / Hide
Range on Protein: 917-1143
Range on HMM: 28-250/253
Sequence Identity: 27% (63 aa)

SRQEPMPAYDRHRVKLHpmlGDPNAdYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPE---DSDTYGDI-
| . .. .|. |.||    .|..  || ||...   ... .| ||.|  . . .||.|.      .|||. .||| |. |...| ..   |.  .... .
nrytniqCcdagrlkla---ddedf-yihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarkitklc

KIMLVKTETLAEYVVRTFA-LERRGYSARhEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTppdaGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVV
.. .. .     .||.   . . |  .   |. .|. .||.||||   .  | ..  || ..|||.||||| ||||  ... ..|.        .. . .
tvikigrkdidkilvrslkrivkagdeev-ivkhihWanWPdhGvPdsflsalrllsvvkkdk----kPivvhCsaGvGrtGtlaliliilealrlpdfq

DIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE
  |   |.  .||| ||.. .  .||      
gvkdllvklreerfravqtevqylyalrcvle

Phosphatase PTPRU.AA Subfamily.R_Nematode_3.PD 908-1143 25 3.2e-34 109.9 In-house 18-264 (267) Show / Hide
Range on Protein: 908-1143
Range on HMM: 18-264/267
Sequence Identity: 25% (64 aa)

TKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDgYHRSNHFIATQGPK--------PEMVYDFWRMVWQEHCSSIVMITKLVE---VGRV
|. ..||.  |.. .| .   ||.|.      . |.|.||..     ....| ||.|          . .  || |. ||...||. . ||    .  ||
tslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeee

KCSRYWPEDSDTYGDIKIMLVKT-----ETLAEYVVRTFALeRRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTppdaGPIVIHCSAGTGR
|.|.||. |.   .. . ||.     |. .. . ||. . .      . |.  ....|.|...| ..  .|. |. |..|.     |.|.|||.| .|..
kcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk----tpvvVHCsdGisR

TGCYIVLDVMLDM-AECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE
.  . ..  .. .. .| .|. . .| | . | . ||||....|.   ||.  
satlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilk

Phosphatase PTPRU.AA Subfamily.N_Nematode_egg.PD 912-1142 25 5e-27 86.4 In-house 25-253 (257) Show / Hide
Range on Protein: 912-1142
Range on HMM: 25-253/257
Sequence Identity: 25% (60 aa)

DKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVgrVKCSRYWPE---DSDT
.. . .|.. ..  .  ||||.   |    |.| ||...|    |.|| .| |  . | ||||||.||..  |||.|  .|    .|  |||    .|  
nylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyywpkaeseslv

Y--GDIKIMLVKTETLAEYVVRTFALERRGYSaRHEVRQFHF-TAWPEHGVPYHATGLLAFIRRvkASTppdagPIVIHCSAGTGRTGCYIVLDVMLdMA
.  | ..|  .| .. |. . |   |   |   . |    |.   .   .  |    .|.|.  .|.     |.|...  |  .... . ... | .   
tvpGslrienlkvdskadplfrvtklklvGgd-deelflehwqgdvnylsdvysplrvlrklrn--lsk-----pvvvqdilGvskaatlvaieial-ls

ECEGV---VDIYNCVKTLCSRRVNMIQTEEQYIFIHDAIL
 |      . ..|. |  ||   ...  .|.|..  .|  
llrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl

Phosphatase PTPRU.AA Subfamily.N_Fungi_PTP1.PD 925-1016 35 3.6e-18 57.1 In-house 57-160 (343) Show / Hide
Range on Protein: 925-1016
Range on HMM: 57-160/343
Sequence Identity: 35% (37 aa)

YDRHRVKLHPMLGD--------PNADYINANYIDGY----HRSNH--FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSdtYG
|.. ||||.  |             |||||||.       .      .||||.| |. | ||.... . .   |...|..||.. || |||.| |  | |
YehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegs--yd

DIKIML
|.. | 
ditvkl

Phosphatase PTPRU.AA Subfamily.N_Nematode_eak.PD 910-1071 23 6.8e-15 46.5 In-house 23-183 (281) Show / Hide
Range on Protein: 910-1071
Range on HMM: 23-183/281
Sequence Identity: 23% (38 aa)

KKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNaDYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDT-
. ..|.  |   .  .||. |.| .   ...  ||||  ..  .  ...| |  .. . |. ||.|| ...  .||.. .|| .  |  .|.|....   
rleavnrnrvvkivpqdrylvrltssqlnrd-GyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevl

-YGDIKIMlVKTETLAEYVVRTFALERRGYSARHEVRQFHFTAWPEHGVPYHaTGLLAFIRRVK
|| ...   |  .. . ...|  |. |     |.|  ...  | |  .|     .||.. .|  
kyGildve-rkeyavkrniletrllilrkGnethrvlhykvfGwtettlpky-edflalrkvmk

Phosphatase PTPRU.AA Subfamily.N_Fungi_PTP1.PD 1078-1142 33 1.5e-11 35.3 In-house 260-339 (343) Show / Hide
Range on Protein: 1078-1142
Range on HMM: 260-339/343
Sequence Identity: 33% (27 aa)

AGPIVIHCSAGTGRTGCYIVLDVMLD------M-A-------ECEGVVD-IYNCVKTLCSRRVNMIQTEEQYIFIHDAIL
. ||..||||| |||| .. || .|       .             . | |   |. | ..|..|.|. .|.|||..|.|
sspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall

Phosphatase PTPRU.AA Subfamily.N_Nematode_eak.PD 1066-1143 21 1.7e-08 25.6 In-house 201-278 (281) Show / Hide
Range on Protein: 1066-1143
Range on HMM: 201-278/281
Sequence Identity: 21% (17 aa)

FIRRVkASTPPDAGPIvIHCSAGTGRTGCYIVLDVMLDMAECE--GVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE
....    |||   || | .. |. |.| ..|.|... . .     .  . . .    |.|.  . .. |. ||....|.
tlkky-ihtppsfapi-iqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivld

Phosphatase PTPRU.AA Subfamily.PTPDC1.PD 1046-1138 26 2.8e-07 21.6 In-house 137-221 (229) Show / Hide
Range on Protein: 1046-1138
Range on HMM: 137-221/229
Sequence Identity: 26% (24 aa)

FHFTAWPEHGVPYhATGLLAFIRRVKASTppDAGPIVIHCSAGTGRTGCYIVLDVMLDMaEcegvVDIYNCVKTLCSRRVNMIQTEEQYIFIH
|.  .....||.   . .|  .. |. .     | | .|| || ||||  |   ..    .    ..  . .|.. |.| . ||| ||...  
fynfglkDygvas-leriLdivkvvdfal--eegkiavHCHAGlGRtGvliacylvyak-r----ltaeeaiklvrskrpksiqtreqvelve

Phosphatase PTPRU.AA Subfamily.RK.PD 1175-1441 59 1.6e-134 438.6 In-house 1-267 (267) Show / Hide
Range on Protein: 1175-1441
Range on HMM: 1-267/267
Sequence Identity: 59% (158 aa)

QLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIV
||.|||.||||||| |..|.|.||...|||.||||||.|..||.|.||||.||||..||||||.|||.|.|||||| .|||.|. ||||||||..|.|||
qlkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgdssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

MLNQLNQSNSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLLVRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAESGDG
||..|........||.|||| ....|| ..||... ..|.|||.|.|||....| ||.. .||.||||.|..|||.|.||...|.|...|.|.|.|...|
mlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeG

RTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLE
|..||||.|.||||||.|...|||||.....||||.|.|||||.|.|||||..||.|.|||.||.||
rivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileale

Phosphatase PTPRU.AA PTPc 1175-1441 31 8.4e-95 322.17 SMART 1-308 (308) Show / Hide
Range on Protein: 1175-1441
Range on HMM: 1-308/308
Sequence Identity: 31% (98 aa)

QLREEFQTLNSVTPPLDVE------ECSIALLPRNR--DKNRSM-DVLPPDRCLPFLISTDG-----DSNNYINAALTDSYTRSAAFIVTLHPLQSTTPD
...|||..| ..||.. ..      .|..| .| ||  ||||.  |... |..   | ...|      ...||||   |.| |. ..|.| .||..|  |
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRLVYDYGCTSIVMLNQLNQS-------NSAWPCLQYWPEPGRQQYGLMEVEFMSGTADE-DLVARVFRVQNISRLQ------EGHLLVRHFQFLRWSA
||| |....|..||||....         |    | ||||.   ..|| ..|...| .  . | . |.|.|.|  . .      . .. |.|...  |  
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPD

YRDTPDSKKAFLHLLAEVDKWQAESGD------------------GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQ
  ..|.| ..||... .|..||. |..                  | ..||| .| ||.|||||  .....|..   ||.|   |..||. |.||.| .|
H-GVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQ

YHFCYDVALEYLE
|.|||...|||..
YIFCYRCILEYIK

Phosphatase PTPRU.AA Y_phosphatase 1203-1438 33 2.9e-77 267.77 Pfam 1-243 (243) Show / Hide
Range on Protein: 1203-1438
Range on HMM: 1-243/243
Sequence Identity: 33% (83 aa)

NRDKNRSMDVLPPDRCLPFLIST-DGDSNNYINAALTDS-YTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWP---CLQYWPE---
|..|||. |....|..   | .. .... .||||   |. |... |.|.| .|...|  |||| |....||.||||...   .   .   | ||||.   
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGR--DEKTCHQYWPDNKE

PGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLLVRHFQFLRWSAYRDTPDS-KKAFLHLLAEVDKWQAESGDG--RTIVHCLNGGGRSGTFC
 . ..|| ..|. .| . ..| . |.|.|.|  . ..  . |.|.... |  . ..|.|  |..| .. .| |||  ...|   ..||| .| ||.||||
GQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDH-GVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFC

ACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALE
|  .......... ||.| . |..||  |.||.| .|| |||.. ||
AIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase PTPRU.AA Subfamily.R_Anemone_2.PD 1177-1440 38 1.9e-60 196.1 In-house 3-261 (262) Show / Hide
Range on Protein: 1177-1440
Range on HMM: 3-261/262
Sequence Identity: 38% (99 aa)

REEFQTLNSVTPPldVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVM
||...|. ..      ... || | |. ||| ...|. |..   |  ..|.   .||||   | |.|. |.| |  ||  |.||||.|.. ... |||| 
seeyerlsrseet--svtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivm

LNQLNQSnSAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEghLLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQAESGDGR
|.... .   . .|||. | ..|| . || .. .  .|.| | |.|..    .|    || |..|.  ...|.|   .|.|. .|.|.|.||| | ..||
ltqeeer-gkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkrteeeee--rqvrqfhytsWpd-egvpesgaslldlvrqvekaqqesgagp

TIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
|  | || |.|.|  ..|| |.  .|||||   |.||. .. ||| |||.|.||| ||.|     
ivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal

Phosphatase PTPRU.AA Subfamily.R_Anemone_1.PD 1177-1440 30 3.2e-59 192.1 In-house 3-257 (258) Show / Hide
Range on Protein: 1177-1440
Range on HMM: 3-257/258
Sequence Identity: 30% (80 aa)

REEFQTLNsvtpPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDG-DSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVM
..|||.|.      . || ..|  ..|..||| .|... | .   | .... .. .||||.  . . .. |||.| .||..|.||||.| .. ...||||
aaefqrlk----eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVm

LNQLNQSNSAwPCLQYWPEpGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLqeGHLLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWqAESGDGR
..|....    | ||||. . ..|| ..|. ..  .  |.. | . ... ..    .  |....|. |.  .  |. ..| |.|. .| |   ..|.   
Ltnliegekk-kchqYwPd-stekygelrvslrkkevfadyiirtlvlskkket--eerevvqyhftvWpd-kgvPqyatavLglrrkvqks-slagarp

TIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
.||| .| ||.|.|..  ..|| .. .. ||.| . |..|. .|.||.| .|| |.. . ||.| 
vvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavleal

Phosphatase PTPRU.AA Subfamily.R_Sponge_2.PD 1182-1440 33 1.5e-58 189.8 In-house 4-261 (262) Show / Hide
Range on Protein: 1182-1440
Range on HMM: 4-261/262
Sequence Identity: 33% (86 aa)

TLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQ
.......  .  ..||| |. |  |||  ..||.|   . | ...    .||||.  |.| |  |.|.|  ||..| .||||.|..|  ..|||| .|. 
eeeksveketefslsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnlee

SNSaWPCLQYWPEP--GRQQYGLMEVEFMSGTADEDLVARVFRVQNISRlQEGHLLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQAESGDGRTIVH
 .    | .||||   ....|| ..| . . .. .| . | ..... .  .||.. |..|.|. |...|... ..|.|...| . | .||..  .|.| .
ngk-ekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskeks-segeadvtqfhfvaWpe-hevPkdatsllelikrvlraqkksgnkaitvv

CLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
| ||.|||.|  .||| ..  . .|||   ||||  .. .|....||.|..|..|||.   
CsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi

Phosphatase PTPRU.AA Subfamily.RA.PD 1175-1440 37 2e-58 189.3 In-house 1-265 (266) Show / Hide
Range on Protein: 1175-1440
Range on HMM: 1-265/266
Sequence Identity: 37% (99 aa)

QLREEFQTLNSVTppLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSI
.|.|||..| ||   .  |.. .| .. |..||| ...|| |    .|   .|    .||||.  | | .   || .  |.. |  ||||..... ...|
gleeefkkltsvk--iqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksati

VMLNQLNQSNSAwPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQ--EGHLLVRHFQFLRWSAYrDTPDSKKAFLHLLAEVDKWQAES
||| .|.. .    | ||||. |   || . ||    |  ||.  | | |....  .  . . ||| | |  |      | . ||.||..| | | .|..
vmltelkerkee-kcaqywpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpev-GvpaegkGmlkllkkvkklqqqs

GDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
   .|||  | ||.|||..  .|||.... ...||| | |.||. .|.||.|  ||.|.| | |||.  
anhpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlleyi

Phosphatase PTPRU.AA Subfamily.RG.PD 1176-1439 29 7.2e-53 171.1 In-house 2-262 (264) Show / Hide
Range on Protein: 1176-1439
Range on HMM: 2-262/264
Sequence Identity: 29% (77 aa)

LREEFQTLNSVtPPLDVeECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDG-DSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIV
| |.|. ....  | |. |.. .  ..|. ||| ..... .|    | .. | |...||||   | | || ..||| .||..|. ||||....   . ||
leeqfeeiqkl-kpkdi-eaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiiv

MLNQLNQSNsAWPCLQYWPE-PGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQaESGD
|| .|...  .  . .|||.  .  ... ..| ..| .  .... | | ..|.   .| .  ||.... .|    ..|.|.  .|      .. . ..  
mltdldekg-rrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPd-mgsPestlfvlifvkkeeaan-keea

GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEY
| ..||. .|.||.||..|  |.|. .. .. |.|.  .|..|. .|..|.| .|| | ||. || 
GPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel

Phosphatase PTPRU.AA Subfamily.R_Ecdysozoa.PD 1176-1439 27 3.5e-46 148.9 In-house 2-267 (269) Show / Hide
Range on Protein: 1176-1439
Range on HMM: 2-267/269
Sequence Identity: 27% (74 aa)

LREEFQTLNSVTppLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIV
| ||...|..        .....    |  |||. |. . |.    |  . |.   .||||.   .|  .  ||.   |...|||||.. .   | ||||
leeeyekLearl--eiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtliv

MLNQLNQSNSAwpCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNIS-RLQEGHLLVRHFQFLRWSAYRDTPDSKKAFLHLLAEVDKWQAES--
 .|.. | .  | .|||.   .||| . |...|    .| . | . | ..     | .  |  ...  | .    |.. .. |.|. .| . .  .    
mlsnlteknrk--cakyWpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnkl

--GDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEY
  .  .||| .| ||||.| | . .|. ..  . ||.|   | ||... .|. ..|| |.|   ..|   
sgsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralady

Phosphatase PTPRU.AA Subfamily.RB.PD 1179-1440 29 2.2e-45 146.5 In-house 5-260 (261) Show / Hide
Range on Protein: 1179-1440
Range on HMM: 5-260/261
Sequence Identity: 29% (77 aa)

EFQTLNSVTPpldVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDG-DSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLN
|...|..|      .... | .. ||.|||   .|| |     | ...  ....||||   . |.    .|.|  ||..|. ||||.|.... |||| ||
eyeelkkvgk---dqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmlt

QLNQSNSaWPCLQYWPEPG-RQQYGLMEVEFMSGTADEDLVARVFRVQNISRlqegHLLVRHFQFLRWSAYrDTPDSKKAFLHLLAEVDKWQAES-GDGR
        | .|||.    ..|| ..|. .. .  .. | | |.... ..    .  ||...|. |. . ..|.. |. |... .|...  ..  .. ..
qlvEkgk-ekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgke----krkvrqyhftsWpdh-gvPektktlldfvrtvreaiekkaskkP

TIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
|||  | ||.||| |  ..|. |. ...||||     ||. . ..| | .|| | ... |..|  
ivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldll

Phosphatase PTPRU.AA Subfamily.N9.PD 1197-1439 36 8.2e-45 144.8 In-house 20-273 (275) Show / Hide
Range on Protein: 1197-1439
Range on HMM: 20-273/275
Sequence Identity: 36% (86 aa)

IALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNsAWPCLQYWP--
. |. | .|||  |||  |.   .| ..|.|.  .||||  .| | .  ||| |  ||. |. ||||.|..  .  |||  .. . .| ||||  |  ..
asklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvverg-rlkcgqywple

EPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHllVRHFQFLRWSAYrDTPDSKKAFLHLLAEVDKWQAE------------SGDGRTIVHCL
..| ..|. ..  . || . ||. ..|.   .. .  | ||||| |  |  .|.| ...|..| .| . ||.   .|||  | ||.|||..    |. ..
eessaefgdlsvsnveveveedykvrvleiknvkteesrk--vthfqflswPdy-GvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcs

NGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEY
  . |||. . |.||. .  .. | .||.|||   |||                    
aGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley

Phosphatase PTPRU.AA Subfamily.N3.PD 1194-1435 28 6.1e-40 128.5 In-house 17-255 (261) Show / Hide
Range on Protein: 1194-1435
Range on HMM: 17-255/261
Sequence Identity: 28% (70 aa)

ECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGdsnNYINAALTD----SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNsAWPCL
.|.| .|.| .|||  |.|| |     | ...    .||||   .    | . .  .|.|  ||..|. |||..|..  .| |||| .| ..     | |
aisaarkpenlaknryrdilpydatrvklkeset---dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverG-rvkCh

QYWPEPG-RQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHllVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQAESgDGRTIVHCLNGGGRSG
||||.. ....| ..|.  .  ...  | | . ... .  .| .  . ..|.| |.   . ||... ||... .| | .. ..  ..|||  | ||.| .
qyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerk--ilqlqylaWpd-hgvPddsadflefvervrklrsgk-eePvvvhCsaGigrtG

TFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDV
 .  | | .| ... | .    .|.|. . ..|.|..||.|  .   
vlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCea

Phosphatase PTPRU.AA Subfamily.RN.PD 1195-1436 33 4.8e-39 125.6 In-house 19-259 (264) Show / Hide
Range on Protein: 1195-1436
Range on HMM: 19-259/264
Sequence Identity: 33% (77 aa)

CSIALLPRNRDKNRSMDVLPPDRCLPFL-ISTDGDSNNYINAA-LTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSnSAWPCLQYW
...|  ..| .|||| .||| |     |  ..  ....||||. ..|.  |..|.| |  || ||  |||..|.. |.. ||.| .|... .| .|||. 
kevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleee-gvkqckryw

PEPGRQQYGLMEVEFMSGT-ADEDLVARVFRVQNISRlQEGHlLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQAEsGDGRTIVHCLNGGGRSGTFC
| . |.. ||...|     .| . | | ..|.   .|    |  | || | . ...| | |..|..   |.|.||| .| ||.|....   ||| ...  
pdeGsevyhiyevhlvsehiwcddylvrsfylknlqt-setr-tvtqfhflswpe-egvPasaksllefrrkvnksyrG-rscpivvhcsdGaGrtGvyi

ACATVLE-MIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVA
. .|.  . . ||. .|..|.| ||..|.. .              
lidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltav

Phosphatase PTPRU.AA Subfamily.N5_RR.PD 1199-1440 28 6.6e-39 125.3 In-house 19-264 (265) Show / Hide
Range on Protein: 1199-1440
Range on HMM: 19-264/265
Sequence Identity: 28% (70 aa)

LLPRNRDKNRSMDVLPPDRCLPFLISTDGDSN--NYINAALTDSYT-RSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAwPCLQYWPEP
....  |||  ..|| ..    | | .....  .||||     |  .| |.. |  ||..|  ||||..|   .. |||| .|...|.  | .|.|.   
evfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrq-kcavyfPda

GRQ----QYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGhllVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQAESGD--GRTIVHCLNGGGRSGT
     .|| .|... . .  .|   | . ... .|...    | |. .  |   ...||. ...|.|..||.. .|.    .  .|||  | || | | |
edyeiserygdveikveeiverndysvrklvlkylervers---vkhywytdWPd-hksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGc

FCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
    .  .| .. |||.     ||  .  ||.| .||.. . .  .||   
fiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclyl

Phosphatase PTPRU.AA Subfamily.RC.PD 1197-1439 31 2e-38 123.7 In-house 20-286 (288) Show / Hide
Range on Protein: 1197-1439
Range on HMM: 20-286/288
Sequence Identity: 31% (84 aa)

IALLPRNRDKNRSMDVLPPDRCLPFL---------------ISTDGD-----SNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVML
||  . |..|||  |||| |     |                |.| |     . .||||.  ||| .   .| .  ||. |  ||||..... |||| .|
iarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivml

NQLNQSNSAwPCLQYWpEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEghLLVRHFQFLRWSAyRDTPDSKKAFLHLLAEV-------DKWQA
.. .    | .|| | |.. || .||..       | . |.. ..|  | .     | ..|.  ||  .. |.  | .|.|.  |        . .| . 
telkeGdre-kcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkds--revtqiqytswsv-eqlpeepkellkliqvvkqklpqkrssea

ES--GDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEY
   .  .||| .| .|.|.|.|  ..|| . . . ||||   | ||. .| ||....|| . |||  |.   
fknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlvet

Phosphatase PTPRU.AA Subfamily.N12.PD 1178-1439 28 3.4e-38 122.7 In-house 4-268 (270) Show / Hide
Range on Protein: 1178-1439
Range on HMM: 4-268/270
Sequence Identity: 28% (76 aa)

EEFQTLNSVTPPLDVEE---CSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSI
.|||.|....  .  |.    . .  ..|. |||  |.|| |     |  ....  ..|||| .    . . ..| .  || .|  ||||.....  . .
kefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveiv

VMLNQLNQSNsAWPCLQYWPEPGRQQ--YGLMEVEFMSGTA-DEDLVARVFRVQNIsrlqEGHLLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQAe
||. .. . .    | .|||| | ..  .| .||. ..  | |.|.. | ..|..     . .  |. |..  |   ...||.|  |.|...| . |  |
vmaCrevelg-kkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaq----kesrkvyqfhytaWPD-hgvPssaksllelielvrelqe-

SGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNL---VDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEY
 |   .|||  | || || .|   | |... ...   .|||    .||. .. .| | .||.. |   .|. 
sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael

Phosphatase PTPRU.AA Subfamily.N_Choan_1.PD 1190-1440 22 8.2e-38 121.7 In-house 12-261 (262) Show / Hide
Range on Protein: 1190-1440
Range on HMM: 12-261/262
Sequence Identity: 22% (58 aa)

LDVEECSIALL-PRNRDKNRSMDVLPPDRCLPFLISTDG-DSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSaWP
..|.. . |   . |. ||| ...   |     .  ..   ...||||   ..|.  ...|.|  |. ..  .||..|...  .|||. .  ...    |
igvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagk-lk

CLQYWPEPG-RQQYGLMEVEFMSGTADEDLVARVFRVqNISRlqEGHLLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGR
 .|||..  . ..| . |...| .. .  . |.|.. . .     .  |...... |   .  |.. |..|.  ..| | . .. .   ..||  | ||.
ChryWPdenselklgdvtvkslseeekktyierkfkl-eres--getreveqlaytaWPd-hGvPattkellefrkavlkatkkktkaplvihCsaGvGr

SGTFCACATVLEMIRCH-NLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
||. |  .... .. . . .||    . ||. .  || |. ||.| | . |..| 
tGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavldal

Phosphatase PTPRU.AA Subfamily.N13.PD 1177-1440 29 8.8e-38 121.7 In-house 3-258 (259) Show / Hide
Range on Protein: 1177-1440
Range on HMM: 3-258/259
Sequence Identity: 29% (80 aa)

REEFQTLNSVTPpldVEECSIALLPRNRDKNRSMDVLPPDRCLPFListdGDSNNYINAALTDSYTRS--AAFIVTLHPLQSTTPDFWRLVYDYGCTSIV
|||..|. . |   ...|...   .|.||||  .||| |.    |    ||. .||||.|           .|..  ||  |. |||..|..  .. |.|
aeefkelrelkp---ldtcevgkkkenkdknryrnvlPydetrvkl----gdeggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaevia

MLNQlNQSNSAWPCLQYWPEPGRQQYGL---MEVEFMSGTADEDLVARVFRVQNISRLQEGHllVRHFQFLRWSAYrDTPDSKKAFLHLLAEVDKWQAes
. . .. .    | .||||  ...  .   .||| .  .  ...| | . |...   .  .  | |..| .|  . ..| |. .....||| . |     
mvtl-ekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesre--vahlnfvkwPdh-gvPssaaelvqfvaevrllqt--

GDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
|  .|||  | ||||.. .  .||..|  .. .||    ..||. .  .| | ||| |.| ..|| |  
dagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl

Phosphatase PTPRU.AA Subfamily.N23.PD 1223-1439 28 3.5e-35 113.1 In-house 124-348 (350) Show / Hide
Range on Protein: 1223-1439
Range on HMM: 124-348/350
Sequence Identity: 28% (64 aa)

ISTDGDSNNYINAALT-DSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSaWPCLQYWPEPG--RQQYGLMEVEFMSGTADEDLVAR
.  |  ..||||.   .  . |  ||.|  |..||  ||| .|..     |||| . .. |    | ||||.     ...| ..|   |.  |  . ||.
stqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnk-lkcdqYwPidegetnlfgdlrvslkslrssegwier

VFRVQNISrlQEGHLLVRHFQFLRWSAYrDTPDSKKAFLHLLAEVDKWQ-----AES---GDGRTIVHCLNGGGRSGTFCACATVLEMIRCHN-LVDVFF
..|     ..   || |...  || .   |.| . .|..| ||..       .|    |.   |.||  | ||.||||.... .. .| ....    ..|
vlhlqhnd--vstvrlvchlhtttWsei-GvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngiinipr

AAKTLRNYKPNMVETMDQYHFCYDVALEY
|. . .||.. ......|.. ||.     
vvrrlrqqRkymvqkkvilkklyeavlea

Phosphatase PTPRU.AA Subfamily.N14.PD 1193-1440 26 6.9e-35 112.0 In-house 16-274 (275) Show / Hide
Range on Protein: 1193-1440
Range on HMM: 16-274/275
Sequence Identity: 26% (68 aa)

EECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDSNNYINAALTDSY--TRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQsNSAWPCLQ
..| | || | .|||  |||| . .   |..|  .|..||||.       ...  .||.  ||. |  |||..|.. | . |||| . ...    ...|.
allstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeee-dgkeksfk

YWPEP----GRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHllVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQAESGDGR---------TI
|.      . ..|  .|     .  . .... .... .   .|    | |.|.  |.  .. |.  | ||. | ||.  ... . .          .|||
ylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeert--vwhlqytDWpd-hgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvl

VHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
..|.||.|       ... . . . .|.  . ..||. .  .|.|. ||.| |.| ..||   
vhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlikyl

Phosphatase PTPRU.AA Subfamily.N_Choan_2.PD 1197-1440 25 3.7e-34 109.5 In-house 15-265 (266) Show / Hide
Range on Protein: 1197-1440
Range on HMM: 15-265/266
Sequence Identity: 25% (65 aa)

IALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTD-SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAwPCLQYWPE
|    ||.  ||..|.||  .    | . . ||  .||||        .....| .  ||..|. .|||....   |.|||. .|.  .    | .|||.
iPeyarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrk-kCerYWpa

PGRQQYGL----MEVEFMSGTADEDLVARVFRVQNisrlQEGHLLVRHFQFLRWS--AYRDTPD---SKKAFLHLLAEVDKWQAESGDG-RTIVHCLNGG
   ..  |    ..|  .|.. .|  ...  |...    .. .  ..||..  |   .   ..|   | .|..|..| ... |  ..  ..||| .| ||
epkekvkladgkikvlalseekeegyiltrlrlek----kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGv

GRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
.||. |  ......  .. |||    . ||......|....||.. | . .||   
gRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya

Phosphatase PTPRU.AA Subfamily.N1.PD 1194-1438 29 1.8e-31 101.0 In-house 19-265 (268) Show / Hide
Range on Protein: 1194-1438
Range on HMM: 19-265/268
Sequence Identity: 29% (73 aa)

ECSIALLPRNRDKNRSMDVLPPDRCLpflISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAwPCLQYWP
|.. | ||.||..||  || | | .    |  . ....||||.| .       .|.|  ||  |.  ||..|..  . ...|||..   |.| ||||.  
etreaklpenrglnryrdvspydhsr---ikleradvdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqi-kCaqywp

EPGRQ---QYG--LMEVEFMSGTADEDLVARVFRVQNISRLQegHLLVRHFQFLRWSAYrDTPDSKKAFLHLLAEVDKWQAES-GDGRTIVHCLNGGGRS
..   ..    ..|...|    .  . | .......  .     . ||.. .|. .   |.| .|||..| .| .  . || ...||  | |||||..  
qeeeeaellleetklkvkliseerksyflvrlleLedletqe--treilhfhyttwpdf-gvpespaafLkfLfkvresgsLssdvgpavihCsagigrs

GTFCACATVLEMIRCHN---LVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALE
 |.|  |  ..    ||.      ||.|.  .. |.|| .| |   ||      
gtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaile

Phosphatase PTPRU.AA Subfamily.N_Nematode_5.PD 1176-1440 24 6.2e-27 85.8 In-house 2-257 (258) Show / Hide
Range on Protein: 1176-1440
Range on HMM: 2-257/258
Sequence Identity: 24% (66 aa)

LREEFQTLNSVTPPLDveECSiaLLPRNRDKNRSMDVLPPDRCLPflISTDGDsNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVM
|..||..|.|..|. .  .|.     .| .|||| ||   |  .   . ||.| ..||||.  .    .  .|.| .||..|. ||||.||.  .||.|.
lktefeklaslkpnke--tck--afeknlkknrskdvkilDetrV--kltded-dsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvl

LNQLNQSNSA-WpclQYWP--EPGRQQYGLMEVEFMSGTADEDLVaRVFRVQNISRLQEGHLLVRHFQFLRWSAYrDTPDSKKAFLHllAEVDKWQAES-
| . .. ..      ...|  .   ...| | ..    . .||     . |. ..  .   ..... ..  |      ||..|. .   ... |   .. 
lvedeelketav---sffpletgdylnlgkmfinnrkvevkedek-keytvevlpegcsesvfakvyhlttWkkk-kvPdkvkkvik--raiekvlskkq

-GDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
  .  ..|.. .| ||.||| . ... | .   . ...    |..|. .|..||...|| . | ..|.|.
gknapvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldyi

Phosphatase PTPRU.AA Subfamily.N20.PD 1200-1440 29 8.9e-26 82.4 In-house 23-256 (257) Show / Hide
Range on Protein: 1200-1440
Range on HMM: 23-256/257
Sequence Identity: 29% (72 aa)

LPRNRDKNRSMDVLPPDRCLPFListdGDSNNYINAALTDSY--TRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQlNQSNSAWPCLQYWPEPGR
| ||.|||  |.|| |     |    | |..||||.            .| |  || ||  |||..| .  .  | |. . .       |.|||   .. 
qpsnreknryrdilpydstrvpl----gkskdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitr-eieggiikcyhywpislk

QQYGLMEVEFMS--GTADEDLVARVFRVQNISRlqEGHLLVRHFQFLRWSAYrDTPDSKKAFLHLLAEVDKWQAesgDGRTIVHCLNGGGRSGTFCACAT
  |  .  .       . .. |.|.| . |        |...|| .|  .  || |  .|.. .    | .     |  .|||  | ||.| | .   |.
kplelkhfrvflenyqilqyfiirmfqvvekst--gtshsvkqlqftkwpdh-gtpasadsfikyiryarkshl---tgpmvvhcsagigrtgvflcvdv

VLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
  |     ....     .|. .  ||.| .|||||||. || |  
vfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivlevl

Phosphatase PTPRU.AA PTPc_motif 1335-1438 31 1.3e-25 92.33 SMART 1-92 (92) Show / Hide
Range on Protein: 1335-1438
Range on HMM: 1-92/92
Sequence Identity: 31% (34 aa)

LVRHFQFLRWSAY----RDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYH
 |.|.... |       . .|.  ...|.....| |         ..||| .| ||.|||||  .....      ||.|   | .|...|.||.| .|| 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYI

FCYDVALE
|||.. ||
FCYRCILE

Phosphatase PTPRU.AA Subfamily.N_Nematode_1.PD 1176-1440 27 6.8e-25 79.3 In-house 2-264 (265) Show / Hide
Range on Protein: 1176-1440
Range on HMM: 2-264/265
Sequence Identity: 27% (73 aa)

LREEFQTLNSVTPPLDVEECSIAllpRNRDKNRSMDVLPPDRCLpFLISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVM
||.||..|.  ...  |.  . |   ...||||  ||   |.     ..... ...|| |      |..  || .  ||..|. ||| .|.     .|||
lrdefralkkfndeekvkafkea---qeadknrykdvgcldknr-vklaeeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivm

LNQLNQsNSAWPCLQYWPEPGRQQYGLMEV------EFMSGTADEDLVARVFRVQNISRLQEG--HLLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKw
| .| . ...  | .|.|   ...  . |       | ..|.   .  . | .| ...    |.. |.|.|.  |   |  |  . | |.||..| .   
lcklie-kgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPd-rGvPpadlaalelleavrg-

qaesGDGRTIVHCLNGGGRSGTFCACATVLE-MIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
    | ..|||  | ||.||  | . .|. ..  ... |.| .|. . . . |  || | . | |.|.      
----skgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllnyf

Phosphatase PTPRU.AA Subfamily.N_Nematode_4.PD 1194-1440 24 7.5e-25 79.2 In-house 17-263 (264) Show / Hide
Range on Protein: 1194-1440
Range on HMM: 17-263/264
Sequence Identity: 24% (62 aa)

ECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDgDSNNYINAALTDSYtRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSaWPCLQYWP
..      .| |||| .|.| .|     |   |  .|.|| |.          .| |  ||. |  ||| .||   .. .||| .| . .    | .|.|
nvtasaseknsdknryadilcidetrvvlknrd-pdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegv-ekcaryyp

EPGRQ--QYGLMEVEFMSGTAD--EDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKwqaESGDGRTIVHCLNGGGR
|   .  ..|  ... .  .     | . . ..| |. .       .|.|.|.|. .|   . .|   .. ..|.  | |   .. ..  .|||  | ||
eksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrd-qvaPldaapviklykavkk---kkkekPivvhcsaGvGr

SGTFCACATVLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
. |.        .||  . ..|    . ||. . . | .  |. |. | .|.. 
tatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvlielf

Phosphatase PTPRU.AA Subfamily.R_Nematode_2.PD 1203-1440 24 1.1e-24 78.5 In-house 29-260 (261) Show / Hide
Range on Protein: 1203-1440
Range on HMM: 29-260/261
Sequence Identity: 24% (59 aa)

NRDKNRSMDVlPPDRCLPFLISTDGDSNNyINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSnSAWPCLQYWPEPGRQQYGL
..||.|  || | .      . .||   . | |   .  ..   ||.|  ||. |. ||| .|  . .  |||| |   . .| .|.|   .|.  |  .
pkdkhRypdv-PCkpetavevivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvek-ekekceeYfpletsqkldl

MEVEFMSG----TADEDLVARVFRVQNISRLQEGHlLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQAesgdgRTIVHCLNGGGRSGTFCACATVLE
.         .....  |...|.. .   . .  |.|.|. .|.. |..|.|..    ||| | .        .||| .| ||...| . . . . .  .
grfsiktvsaekilkdeiekrtlkvedstgkfatr-tvthyqyeeWpd-rgvPkshaelfeLlelvkksek-----PivvhCsaGiGRtmafigteylar

MIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
. . .  | | ||..... . |  |...   .|| .|     
eveadptieltealkelrehRwkgiqtesqlywltlgalyrl

Phosphatase PTPRU.AA Subfamily.N_Nematode_6.PD 1201-1440 25 1.3e-24 78.4 In-house 22-252 (253) Show / Hide
Range on Protein: 1201-1440
Range on HMM: 22-252/253
Sequence Identity: 25% (61 aa)

PRNRDKNRSMDVLPPDRClpfLISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAwPCLQYWPEPG--RQ
...|.||  ..   |.    ..  ..| . || | | .. |..  .|.|  ||..|  .||...   | ..|||| .| ...   . .| ..     ...
lkfkdrnrytniqCcdag---rlkladdedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvekgke-ksaeylsdkvGdar

QYGLMEVEFMSGTADEDLVARvFRVQNISRLQEGHLLVRHFQFLRWSAYrDTPDSKKAFLHLLAEVDKWQAesgdgRTIVHCLNGGGRSGTFCACATVLE
. .  .   |  | | .     .. |..  . . .|.|...  |  .   ||| .. |.||.| | .        .|||  | || ||.    ..|| .|
kitklctvikigrkdidkilv-rslkrivkagdeevivkhihWanWPdh-GvPdsflsalrllsvvkkdkk-----PivvhCsaGvGrtGtlaliliile

MIRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYL
  .  .|      ||. .   |.|. || . .   ||||   
alrlpdfqgvkdllvklreerfravqtevqylyalrcvleyl

Phosphatase PTPRU.AA Subfamily.R_Nematode_3.PD 1230-1437 21 2.5e-19 61.1 In-house 51-263 (267) Show / Hide
Range on Protein: 1230-1437
Range on HMM: 51-263/267
Sequence Identity: 21% (47 aa)

NNYINAALTdSYTRSAAFIVTLHPL--------QSTTPDFWRLVYDYGCTSIVMLNQLNQ--SNSAWPCLQYWPEP--GRQQYGLMEVEF--MSGTADED
...|.| .  .   .. .|.|  |.        .|| . || .. ... ...||| . .   ..    | .|.||   | ... ..|.   ..  ..|| 
ddfihAnvv-ecpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYypekvdgelkfegvsvkctdikkelsed

LVARVFRVqNISrlQEGHLLVRHFQFLRWSAyRDTPDSKKAFLHLLAEVDKWQAEsgdgrTIVHCLNGGGRSGTFCACATVLEMIRCHN-LVDVFFAAKT
. | ..| ..   .. .  |.| ..  |.. . .|...| .|.|.  | | ..       .||| .| .||.|. |   . ..|  ..  .|.    | |
vekrtlvv-tfe--kkkeftvthllykgWke-lnapeepkealelikfveksktp-----vvVHCsdGisRsatlaaielgyqliikskgkldllslike

LRNYKPNMVETMDQYHFCYDVAL
|. ... ..|  .. |   . | 
lrkqRagaiqtelelafvilgil

Phosphatase PTPRU.AA Subfamily.N_Nematode_egg.PD 1230-1440 22 1.9e-16 51.7 In-house 54-256 (257) Show / Hide
Range on Protein: 1230-1440
Range on HMM: 54-256/257
Sequence Identity: 22% (49 aa)

NNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSawpCLQYWPEP----GRQQYGLMEVEFMSGTADEDLVARVFRVQN
...| |   .       ||..  ||. |  ||||.|.   .  ||||.   .|.    |  |||       .   | ...| .      | . || ... 
ddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakeser---ceyywpkaeseslvtvpGslrienlkvdskadplfrvtklkl

ISRLQEgHLLVRHFQFlRWSAyrdTPDSKKAfLHLLAEVDKwqAesgDGRTIVHCLNGGGRSGTFCACAT-VLEMIRCHNL-VDVFFAAKTLRNYKPNMV
.   .|  | . |.|   .     . |     |..|  . .  .      ..|.. .|...|. |  . .|...|       |  | . ||  ..  ||.
vGgdde-elflehwqg-dvny---lsdvysp-lrvlrklrn--l---skpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsv

ETMDQYHFCYDVALEYL
. .| | | . | ..  
esvllylfvyrlvlffi

Phosphatase PTPRU.AA Subfamily.N_Nematode_eak.PD 1204-1351 24 1.2e-09 29.3 In-house 27-170 (281) Show / Hide
Range on Protein: 1204-1351
Range on HMM: 27-170/281
Sequence Identity: 24% (35 aa)

RDKNRSMDVLPPDRCLPFLISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQlNQSNSAWPCLQYWPEPGR-QQYGL
..|| ....| || |  | |.  . . ||||.|..       .|.|  . ..  . ||..|..    .||.| . .  ..|.|. .   .|| ..||  .
vnrnrvvkivpqdrylvrltssqlnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlle-dveekleksdkyfpdktevlkyGi

MEVEFMSGT-ADEDLVARVFRVqniSRLQEGHLlVRHFQFLRWSAYrDTP
 .   . |  | . .   .. .| |  | |...  |. . ..|       
ldverkeyavkrniletrllil---rkGnethr-vlhykvfGwtet-tlp

Phosphatase PTPRU.AA Subfamily.N_Fungi_PTP1.PD 1228-1299 29 8e-09 26.3 In-house 79-155 (343) Show / Hide
Range on Protein: 1228-1299
Range on HMM: 79-155/343
Sequence Identity: 29% (23 aa)

DSNNYINAAL---T-DSYTRSAAF--IVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAwPCLQYWPEPGRQQ
.|.||||     |  |    . |  | |  ||.||  ||.....  . . |..|...   |    | .||.| . .. 
stnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnle-kcyrYWqegsydd

Phosphatase PTPRU.AA Subfamily.N_Fungi_PTP1.PD 1375-1439 25 2.8e-06 17.9 In-house 262-341 (343) Show / Hide
Range on Protein: 1375-1439
Range on HMM: 262-341/343
Sequence Identity: 25% (20 aa)

RTIVHCLNGGGRSGTFCACATVLE------MIR--------CHNLVD-VFFAAKTLRNYKPNMVETMDQYHFCYDVALEY
.|||  | || ||...   .|.      ...          .. | ...  . ||. . .|| ..||. |.|. .| |  
pilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfy

Phosphatase PTPRU.AA Family.DSP.PD 1321-1395 22 6.3e-06 17.2 In-house 148-207 (387) Show / Hide
Range on Protein: 1321-1395
Range on HMM: 148-207/387
Sequence Identity: 22% (17 aa)

FrvqnisrlqeghllVRHFQFLRWsAYRDTPDSKKAFLhLLAEVDkWQAE---SgDGRTIVHCLNGGGRSGTFCACAT
.                ....||. .  |.. .. . | .   .| .  |   |  |.  |||  | ||||| ...  
k--------------elgikylri-pidDhnapplenl-fekaid-fieegnds-kgvVlVHCkaGkgRsgtliiaYl

Phosphatase PTPRU.AA Subfamily.DSP14.PD 1323-1421 22 1e-05 17.0 In-house 30-125 (138) Show / Hide
Range on Protein: 1323-1421
Range on HMM: 30-125/138
Sequence Identity: 22% (22 aa)

VQNISRlQEGHLLVRHFQFLRWSAyRDTPDSKkAFLHLLAEVDKW-QAESGDGRTIVHCLNGGGRSGTFCAcAtVLEMIRCHNLVDVFFAAKTLRNY-KP
. |... .. .  ..... ..    .|.|..|    |.   .||  .... .|.|.||| .|  || ...  |  |   .. .| . .. |. |.  .||
ivnvtt-elpetkledvktvkikv-eDkpeak-laehfdevadkieevkkkgGktlvhCvaGvsRsAslvl-a-ylmkyeklsLreayklvksaRpiirP

N
 
n

Sequence
Name Sequence Type Origin Length Description Download
PTPRU.AA Protein None 1446 None Fasta, JSON
PTPRU.NA RNA None 4338 None Fasta, JSON
PTPRU.AA.PD2_1175-1441 Protein Phosphatase Domain None 267 None Fasta, JSON
PTPRU.AA.PD1_893-1146 Protein Phosphatase Domain None 254 None Fasta, JSON