PTPRN
Species: Human
Alias: ICA512, IA-2/PTP, FLJ16131, PTPRN, IA-2, R-PTP-N, IA2
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RN
Protein domain

Protein domains of PTPRN.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Receptor_IA-2 PTPRN.AA Receptor_IA-2 468-558 64 1.1e-62 219.3 Pfam 1-91 (91) Show / Hide
Range on Protein: 468-558
Range on HMM: 1-91/91
Sequence Identity: 64% (59 aa)

AEEYGYIVTDQKPLSLAAGVKLLEILAEHVHMSSGSFINISVVGPALTFRIRHNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVGQRE
.||||||.|||.|||. .||.|.||||..|||....||||.|||||.|||.||||||...|||..||...|..||.||||.|||.|||.|.
DEEYGYIITDQDPLSTDEGVHLMEILAHMVHMHMSDFINIWVVGPAVTFRVRHNEQNMTTADVAKQAVDNKHQLEKQTGLRILQSGVGYRG

Phosphatase PTPRN.AA Subfamily.RN.PD 708-971 76 1.1e-156 511.0 In-house 1-264 (264) Show / Hide
Range on Protein: 708-971
Range on HMM: 1-264/264
Sequence Identity: 76% (203 aa)

RLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIV
||.|||.|||||.|||.|...|. | |.||||. ..|||||.|.||| |.| ..|||||||.|..||||.|||||||||||.|||||||||||.|..|||
rlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvviv

MLTPLVEDGVKQCDRYWPDEGASLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIV
.||.| |.|||||.|||||||...||.|||.||||||||.|.|||||||||.||.||||.|||||||||.||.|||...||.|||||||.||||||||.|
nltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivv

HCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVN
||||||||||.|||||.||.|..||||||||||||||.||||||||..||||||||||||||||
hcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeevn

Phosphatase PTPRN.AA PTPc 708-971 32 1.3e-112 381.33 SMART 1-308 (308) Show / Hide
Range on Protein: 708-971
Range on HMM: 1-308/308
Sequence Identity: 32% (102 aa)

RLAKEWQALCAYQAEPN--------TCATAQGEGNI--KKNRHP-DFLPYDHARIKLKVESSP----SRSDYINASPIIEHDPRMPAYIATQGPLSHTIA
 ...|.. |.... ...        .| .|. . |.  .|||.. | ..||| |.||| . .     . ||||||. |  . .|  .||.||||| |||.
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGY-WRPKRYICTQGPLPHTIE

DFWQMVWESGCTVIVMLTPLVED--------GVKQCDRYWPDEGASLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQT--------QETRTLTQFHFLSWP
|||.|||. .|..||||. ..|         |.. |..|||||    |. ..|...||.....|. .| |...| ..        .||||.|..|. .||
DFWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

AEGTPASTRPLLDFRRKVNKCYRGR-------------------SCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKD
  |.| |....|||.|.|..... .                   . ||.||||.|.|||||...||...... .    .||  .. ..|.||||.| ...
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN----VDIFQIVKMMRNQRPGMVQTEE

QFEFALTAVAEEVN
|. |   ...| . 
QYIFCYRCILEYIK

Phosphatase PTPRN.AA Y_phosphatase 734-968 41 1.7e-112 384.8 Pfam 1-243 (243) Show / Hide
Range on Protein: 734-968
Range on HMM: 1-243/243
Sequence Identity: 41% (103 aa)

NIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGV-KQ-CDRYWPD---EG
| .|||..| ..||| |.||. . ..  ||||||. |  ....  |||.||||..|||.|||.|||. .||.||||. ..|.|  .. |..||||   ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

ASLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQT--QETRTLTQFHFLSWPAEGTPAS-TRPLLDFRRKVNKCYR-GRSC--PIIVHCSDGAGRTGTYILI
   |  ..|..|||.  |.|. || | ..| ..  |||||.|..|...||  |.| | ....|||.|.|.|... ....  ||.||||.|.|||||...|
PMTYGDFQVTCVSEEH-CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAI

DMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
|... .| .. .  ||  ...|.| ||||.| . .|..|   ...|
DIMCQQMEHEGTV-DIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase PTPRN.AA Subfamily.R_Anemone_2.PD 709-970 40 1.1e-75 245.7 In-house 2-261 (262) Show / Hide
Range on Protein: 709-970
Range on HMM: 2-261/262
Sequence Identity: 40% (106 aa)

LAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASpIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVM
| .|...|   .... |. .|. . | .|||. . |.||..|.||.  ..   ||||||.  |.   |  ||||||.||..|| |||.|||| ...||||
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinan-yidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivm

LTPLVEDGVKQCDRYWPDEGASLYHVYEVNLVSeHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCY-RGRSCPIIV
|| ..| | ....||||..|.  | .  |.| . .. ..|...||| .|. ...|.|.. |||. ||| ||.|.|.  |||. |.|.|   .    ||.|
ltqeeergkakvhryWPskgsrsygklvvelke-evelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivv

HCSDGAGRTGTYILIDMVLNRMAKgVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEV
||| | ||||..| .|..|.|...  . .|.  |....|.||. .|. |||.||... | .  
hcsaGvGrtGvfiavdillerika-ealvdvfqtvkqlreqrnlmvqtkdqyefiydvlleal

Phosphatase PTPRN.AA Subfamily.R_Anemone_1.PD 709-969 39 7.1e-75 243.2 In-house 2-256 (258) Show / Hide
Range on Protein: 709-969
Range on HMM: 2-256/258
Sequence Identity: 39% (102 aa)

LAKEWQALCAYQAEpnTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRmPAYIATQGPLSHTIADFWQMVWESGCTVIVM
.|.|.| |   ..|  .  .|. . | ||||. | ...||.|. |. .|. ..||||||| .  .| .  |.||||.||..|..|||.|||.  ..||||
yaaefqrlkeikee--ekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdkt-rafiatqapleetvedFWrmvwqekigviVm

LTPLVEDGVKQCDRYWPDeGASLYHVYEVNLVSEHIWCeDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIVH
|| |.|   |.| .|||| ... |  ..|.| ..     |. .|.. |......|.|...|.||..||| |  .. .|..||||.|  .  . |..||||
LtnliegekkkchqYwPd-stekygelrvslrkkevfa-dyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvh

CSDGAGRTGTYILIDMVLNRmAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEE
.| ||||... || .|.. ||  | .||  ... .| .|| .|..|.|. |.|| |     
CsaGvgRtGaflvidamleq-akkekvvDifnyvkairedrphmvqtkeqyvfihlavlea

Phosphatase PTPRN.AA Subfamily.R_Sponge_2.PD 722-970 38 2e-71 231.7 In-house 13-261 (262) Show / Hide
Range on Protein: 722-970
Range on HMM: 13-261/262
Sequence Identity: 38% (97 aa)

EPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVeSSPSRSDYINASPIIEHdPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCD
.  .. .|. . |. |||... ||||. |..|.  .  . ||||||| .  .  |  |||||||||..|..||| ||||   . ||||| |.|.| ..| 
tefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgy-krrkayiatqgPlketveDfWRmvweykvstivmltnleengkekca

RYWPDE--GASLYHVYEVNLVSEHIwCEDFLVRSFYLKNVQTQET-RTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYR-GRSCPIIVHCSDGAGRTG
.|||..  ..  |  ..|.|..|.   .|. .| . |.. ...|  ...|||||..|| ...|... .||....|..  .  .. .|.|.||||.|||||
kYWPekvdeeveygkfkvtlkeeek-ladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtG

TYILIDMVLNRMaKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEV
.| .|.||.|. |  .|||.  .|...| .|.|||. ..|..|   |..| . 
tfialdsvlerl-kaeeeidvfevlktlrtkriglvqdaaqYvfihdalleyi

Phosphatase PTPRN.AA Subfamily.N12.PD 725-970 39 2.2e-70 228.0 In-house 23-269 (270) Show / Hide
Range on Protein: 725-970
Range on HMM: 23-269/270
Sequence Identity: 39% (99 aa)

TCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASpIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYW
. .... | |.||||. | ||||..|..|. ...   ||||||. .|..     .|||.||||..|. |||.|.||   ...||.  .|| ||.|.||||
steagekeenvkknrykDilPydksrvelskieeeegsdyinan-fikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryW

PDEG-ASL-YHVYEVNLVSEHIWCEDFLVRSFYLKNVqtQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIVHCSDGAGRTGTYILI
.||  .| .  .||.| .|.   .|||.|.. ...   .|.|...|||. .||  |.|.|. .||.. ..|..  .  . |..|||| | ||||| | ||
peegeeelefgefevtleeekavdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiai

DMVLNRMAKGVK--EIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEV
.| . . ..    |.|.   . ..| ||. ||..|.|.|.   |||| | 
dyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv

Phosphatase PTPRN.AA Subfamily.RB.PD 724-967 38 8.5e-70 226.3 In-house 16-257 (261) Show / Hide
Range on Protein: 724-967
Range on HMM: 16-257/261
Sequence Identity: 38% (95 aa)

NTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDpRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRY
.....|. . | .|||.   |||||.|.||.  .. | .|||||. | ..   .  ||||||||..|. |||.||||. ...||||| ||| |..|..||
qavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgyn-spreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeY

WPDEG-ASLYHVYEVNLVSEHIwCEDFLVRSFYLKNvqTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGR--SCPIIVHCSDGAGRTGTYI
|..  . ||   .|.|..|.   ... .|.| ...   .|.|...|.||.|||  |.| .|..|||| |.|..  . .  . ||.|||| | |||||.| 
WPadeepvlyGdikvtllaeke-ldewvirefkiek--gkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfi

LIDMVLNRMAKgVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVA
.|..|... .    .|..... ..| .|  || ...|. |  .... 
aldrllqaiee-ndyvdvfgvvaelReeRnllvqtekqyifihecll

Phosphatase PTPRN.AA Subfamily.RA.PD 709-968 38 1.8e-69 225.2 In-house 2-263 (266) Show / Hide
Range on Protein: 709-968
Range on HMM: 2-263/266
Sequence Identity: 38% (102 aa)

LAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIiEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVM
| .|...| . .   ... ||. | | ||||  . ||||..|. | | .    ||||||| | .   .   .||.|||...|. |||.|.||.. |||||
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfi-dGyrekdkfiaaqGpkeetvedfwrmiweqksativm

LTPLVEDGVKQCDRYWPDEGASLYHVYEVNLvSEHIWCEDFLVRSFYLK----NVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSC-
 | | . ..| .||||||.  |    |..  ..  .||. || | ..    . . ...| ..|||| |||  | ||... .|.. .||.|. .  .  ||
ltelkerkeekcaqywpdeGlvtyGeirvev-kdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanh

PIIVHCSDGAGRTGTYILIDMVLNRMaKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
.|||| |.|||||.| .| ||.|. |  . .|.  .....| ||| .|... |.||   .. |  
pivvhcsaGvGrtGtfivldavlerv-kaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle

Phosphatase PTPRN.AA Subfamily.N6.PD 710-968 37 8.9e-67 216.6 In-house 15-292 (295) Show / Hide
Range on Protein: 710-968
Range on HMM: 15-292/295
Sequence Identity: 37% (104 aa)

AKEWQALCAYQAEPN-TCATAQGEGNIKKNRHPDFLPYDHARIKLK-VESSPSRSDYINASPI--------IEHD----PRMPAYIATQGPLSHTIADFW
.|.. |. ...| . ..  ..   | .|||  . ||.||.|..|| .|.| . ||||||. |          .      ..  ||||||.|..|..|||.
weefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFW

QMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGAS-LYHVYEVNLVSEhIWCEDFLVRSFYLKNV-QTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRK
|||.  ..||||.|  || | ..| ||||||. .  . |..|. .||    .|. .| | ...  . .|.|.. |.|| .||  |.|...  .|.| ..|
rmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisE-kstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfled

VNKCYR--GRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGV--KEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
|| ..   .. ||.||||.| |||||.|.||.||. . .     .|||  ....|| || ||| ...|..| ..||.  
vnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavqf

Phosphatase PTPRN.AA Subfamily.RK.PD 709-969 35 1.8e-66 215.2 In-house 2-265 (267) Show / Hide
Range on Protein: 709-969
Range on HMM: 2-265/267
Sequence Identity: 35% (94 aa)

LAKEWQAL--CAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPsRSDYINASPIiEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVI
| .|...|   ... . . | .|. . | .|||  | |.||.....|..      ||||||. | .   |  |.|.||||| .|..|||..|...|. ||
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaali-dsykrpaafivtqgPlqetvkdfWrlvydencasi

VMLTPL-VEDGVKQCDRYWPDEGASLYHVYEVNLVSEHIWcEDFLVRSFYLKN--VQTQETRTLTQFHFLSWPAE-GTPASTRPLLDFRRKVNKCYRG-R
||| | || |  .| .|||...   |   .|.||. ..  .|..|| | ...   . .|.|.. ||.||.||.  ..| | | ||..|.|.|     .  
vmlteldvevgrvkClkyWPedtevrygdikvelveaeld-adlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeee

SCPIIVHCSDGAGRTGTYILIDMVLNrMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEE
.|.|||..||||.||.| ||.||. |..  . .|.  .   .|.... .|  ..|..|   .. |   
eGrivvhClaGaGrsGtfiaidivle-mieregvvdvfnavktlrnrkvnmveteeqykfvydvilea

Phosphatase PTPRN.AA Subfamily.N3.PD 720-966 37 4.8e-66 213.8 In-house 11-256 (261) Show / Hide
Range on Protein: 720-966
Range on HMM: 11-256/261
Sequence Identity: 37% (95 aa)

QAEP-NTCATAQGEGNIKKNRHPDFLPYDHARIKLKveSSPSrsDYINASPIIEHDPR---MPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVED
. .|  .. .|.   |..|||. | ||||..|.|||  .|..  |||||. .    |    .  ||||||||..| .||||||||  .|.||||| |||.
rkkpglaisaarkpenlaknryrdilpydatrvklk--eset--dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlver

GVKQCDRYWPDEGASL-YHVYEVNLVSEhIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPIIVHCSDGAG
| ..| .|||... .| .  ..|.. .|    . ...| ..||. .|.| |...|. .|.|| .| | ..  .|.| ..|.|. .|..|..|||| | ||
GrvkChqyWPetedelefgefsvrceke-detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGig

RTGTYILIDMVLNrMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAV
|| .||... |  .    ... . . . ..||||  ||....|..|   |. 
rtGvlilletala-lieaaepvypldivrtmrdqramlvqtvsqykfvCeai

Phosphatase PTPRN.AA Subfamily.N_Choan_1.PD 712-969 34 7.5e-66 213.4 In-house 5-260 (262) Show / Hide
Range on Protein: 712-969
Range on HMM: 5-260/262
Sequence Identity: 34% (89 aa)

EWQALCAYQAEpNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDpRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTP
|...| . . . ||.  .. . |..|||. .   ||..|.|.. ... . .|||||. .   .    .|||||||. .....|||||||   ..|||.| 
eyeklaeigvd-ntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgyk-gekeyiatqgPvPaslvsfWqmvweqkvsaivmvtr

LVEDGVKQCDRYWPDEGA-SLYHVYEVNLVSEHIwCEDFLVRSFYLkNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRS-CPIIVHC
 .| |  .| |||||| .   .  . |. .||.   . .. | | | . .. |||...|.....||  | ||.|. ||.||..|.|. . .. .|...||
eieagklkChryWPdenselklgdvtvkslseee-kktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihC

SDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEE
| | ||||||| .| .......  ...|. |.....| .|  .|..  |.||   || . 
saGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavlda

Phosphatase PTPRN.AA Subfamily.RG.PD 709-967 34 2.9e-65 211.5 In-house 2-260 (264) Show / Hide
Range on Protein: 709-967
Range on HMM: 2-260/264
Sequence Identity: 34% (89 aa)

LAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDpRMPAYIATQGPLSHTIADFWQMVWESGCTVIVM
|.......   ...  ...... | | .|||. . ......|.||.  .    .|||||| |  .  |  .||.||||| .|| |||.|.||..||||| 
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyr-rskeyivtqgplketiedFWrmiWehnaqiivm

LTPLVEDGVKQCDRYWPD-EGASLYHVYEVNLVSEHIWcEDFLVRSFYLKNVQTQETRT--LTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGRSCPI
|.| | ...|.|||. ...  .  ..|.|.|..   ... ||.| ||| .... ..   .|.|. .||  |.| || . | | .|... . .. ||.||.
ltdldekgrrdedvyWPkkdeplelealkvtllskekl-skytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPi

IVHCSDGAGRTGTYILIDMVLNRMAKgVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVA
| |.||.|||| .| .|... |  . ...  .| ..| .||||| ...|. |   |.     
vvhdsaGvgragtyialdtllqqlek-eeavnvyqvlklirakRpglvtteEqyvfiydall

Phosphatase PTPRN.AA Subfamily.R_Ecdysozoa.PD 709-968 31 2.8e-62 201.5 In-house 2-266 (269) Show / Hide
Range on Protein: 709-968
Range on HMM: 2-266/269
Sequence Identity: 31% (86 aa)

LAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMpAYIATQGPLSHTIADFWQMVWESGCTVIVM
|..|.. | |    . .. ... . |  |||..|  ..|. |.|||.      ||||||| |. .. .   .|| |.|.  || |||.|..|   |.|||
leeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekk-kfiaaqdPveatigDfWrmiaeqevtlivm

LTPLvEDGVKQCDRYWPDEGASLYHVYEVNLVSEHIwCEDFLVRSFYLKNVQ---TQETRTLTQFHFLSWP-AEGTPASTRPLLDFRRKVNKCYRGR---
|. | ..  ..|..|||.|    |    |.||||.  ..|.  |.... ...    ...| ..|... .|.     | ..| ||.. ..|.. |.     
lsnl-teknrkcakyWpiedevqygdilvklvseek-hsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnkls

--SCPIIVHCSDGAGRTGTYILIDMVLNRMAKgVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
    ||.|||| |.||.|... .|..|... .  ...|| .|  ..| ||. ||.| .|..|   |.|.
gsrsPivvhCsaGvgrsgifvaldlllqqlka-edkvdifetvkkLrsqrnllvqsleqyvflyralad

Phosphatase PTPRN.AA Subfamily.N13.PD 711-967 36 3.7e-62 201.4 In-house 4-255 (259) Show / Hide
Range on Protein: 711-967
Range on HMM: 4-255/259
Sequence Identity: 36% (94 aa)

KEWQALCAYQAEpNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSpsrsdYINASPI-IEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVML
.|.. |   ..  .|| ... . | .|||. . ||||..|.||. |..     ||||| | .. .     |||.|||| .|..||||||||..||.|.| 
eefkelrelkpl-dtcevgkkkenkdknryrnvlPydetrvklgdegg-----yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamv

TPLVEDGVKQCDRYWPDEGASLYHVYE---VNLVSeHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRgRSCPII
 .|.|  .|.||||..  .  .|..   |.|.      ..| ||.. .|.....|.| .....| .||  |.|.|. .|. | ..|..  .  . ||.||
tlekekgkvkchrywPerknkklkvsnrlevellk-vqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPiv

VHCSDGAGRTGTYILIDMVLNRMAKGVkEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVA
|| | ||.|..| ||.||. ...   |.|.  .....|.|| |.|..|||. |   |.   
vhcsaGiGrsGvlitidvvlglierdk-efdvkeivrklreqrqgvvqtkdqyifvykail

Phosphatase PTPRN.AA Subfamily.N9.PD 724-968 41 5.1e-61 197.7 In-house 16-272 (275) Show / Hide
Range on Protein: 724-968
Range on HMM: 16-272/275
Sequence Identity: 41% (102 aa)

NTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASpIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRY
|  ...  .|..|||. | | ||..|.||. ..  . ||||||.  ..   .  |.||||||| .|. |||.||||. . |||| | .|| |.| .|||.
Gtflasklranleknrytdvlcydetrvklakldedeasdyinan-fvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqy

WPDEG--ASLYHVYEVNLVSEHiWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKC-------------YRGRSCPIIVH
|   .. .  ..|. |. .   ||. ||.. .|||.|.|.|..| | |||||  |.| |.  |||...|| ... .  ||.|||| | |||||.| .|. 
wpleeessaefgdlsvsnveve-veedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvh

CSDGAGRTGTYILIDMVLNRMAKgVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
|.|. . |  .|.  |....| ||   .. ..|.||   || |                 
csaGiGrtGtfitldiclarlee-vgtvdvvetvkllrtqrafsiqtpeqyefcylavle

Phosphatase PTPRN.AA Subfamily.N5_RR.PD 732-967 33 2.4e-56 182.2 In-house 21-261 (265) Show / Hide
Range on Protein: 732-967
Range on HMM: 21-261/265
Sequence Identity: 33% (82 aa)

EGNIKKNRHPDFLPYDHARIKLKVESSPSR-SDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGAS
|. .|||. . || ...|. |. ||| .  |.||||  |  .| .  ||.||||||..||||||.|...  ..|||||| | |   ..|.|.||.     
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedy

----LYHVYEVNlVSEHIWCEDFLVRSFYLKNVQTqETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRG---RSCPIIVHCSDGAGRTGTYILID
   |   |.. |.| . ..|. ||...||...   .|... . . .|| . .| ....|||. ..|..  .    .  |..|||| | |||| .| |.. 
eiserygdveik-veeiverndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiais

MVLNRMAKGvKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVA
.... .  . .|.  .  ..| .| |.|....|.|.   |..  
iavrqlree-ivvdvlkivcnlrldrGGmvqtseqyelihralc

Phosphatase PTPRN.AA Subfamily.N1.PD 725-969 38 1e-55 180.2 In-house 19-266 (268) Show / Hide
Range on Protein: 725-969
Range on HMM: 19-266/268
Sequence Identity: 38% (96 aa)

TCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSpsrsDYINASpIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYW
...|. . | ..||. |  ||||.||||. ..     |||||| ..| .     || |||||.||.  |||||||  .  ..||  .|| ..|  ||| |
etreaklpenrglnryrdvspydhsrikleradv----dyinas-lveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqyw

PDEGAS----LYH-VYEVNLVSEHIwCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNK--CYRGRSCPIIVHCSDGAGRTG
  .    | .  ..|.|.||..  . |||| . |....|||||....||.  ||  | | |   .|.|  || .  .      |...||| | ||.||. 
pqeeeeaellleetklkvkliseer-ksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsg

TYILIDMVLNRMAKGVK--EIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEE
|.| .| .. |  .   .||   | ..| .| ||.   || .|. .|. |    
tlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaileg

Phosphatase PTPRN.AA Subfamily.N14.PD 722-966 33 4.8e-54 174.6 In-house 14-270 (275) Show / Hide
Range on Protein: 722-966
Range on HMM: 14-270/275
Sequence Identity: 33% (84 aa)

EPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPsRSDYINASPIIE-HDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQC
|  .. ||. . | .|||..|.|||...|..|.      ...||||| |      .   ||..|||| .|. ||||||||.| ..|||||||| ... .|
edallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeks

DRYWPDEGASLYHV-YEVNLVSEHIW--CEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVN-------KCY---RGRSCPIIV
.|... .  .| ..   |...     . .  ... || . ..| ||.  . .  || .| |   ...|.| ..|.       .. .. |..||||.|.||
fkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlv

HCSDGAGRTGTYILIDMVLNRMAKGvKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAV
||  || |.... . .. .||||  .|...| ||  ||..  |..|  ...        
hCsaGvGrtGvlilsdlliatlehn-eeidikkvlarLrkqrmllvqtlaqykfvykvl

Phosphatase PTPRN.AA Subfamily.N23.PD 720-968 36 4.3e-52 168.4 In-house 90-347 (350) Show / Hide
Range on Protein: 720-968
Range on HMM: 90-347/350
Sequence Identity: 36% (91 aa)

QAEPNtCATAQGEGNIKKNRHPDFLpYDHARIKLKVESSP-SRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVK
.| |.     | ||  ...  ||    |..|.||.. . | ...|||||. . |  |  | .||||||.  |.||||.||||    |||||||| . ..|
tavpq-prhlqtegsGqqqgtpdsr-hdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnkl

QCDRYWPDE-G-ASLYHVYEVNLVSEHiWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCY---RGRS------CPIIV
|.||| . | . |.  ..| | |..   | .  | . |.  ...  |.....|. .|.  | |.|   ||.|  .|...|   ||||.||| | |||||.
kcdqYwPidegetnlfgdlrvslkslr-ssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiil

HCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
 ..  ... . .|   |.|   ....| ||   |. |.....  .|| |            
hCsaGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkklyeavle

Phosphatase PTPRN.AA Subfamily.RC.PD 710-968 32 4.6e-52 168.2 In-house 3-285 (288) Show / Hide
Range on Protein: 710-968
Range on HMM: 3-285/288
Sequence Identity: 32% (92 aa)

AKEWQALCAYQAEpNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVE-------------S------SPSRSDYINASPIIEH-DPRmpAYIATQGPLSH
|.| |  ...   |   |. | | .|||. | ||||. |..|| |             |      |   |.||||| |  . .|.   |||.||||  |.
eaefqrlpsvrsk-rtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpe--kyiaaqGplke

TIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWpDEGASLYHVYEVNLvSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLD
 |||.|..|   .|||||| | |   ..| .|| .||   |   ||.|  ..  . |...| . |.| . ...|..||. . ||.|. |.  . ||..  
tvddfwrmiferkvkvivmltelkeGdrekcaeyw-eeGkrayGdvevdl-kdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellk

F----------RRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRmAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
        .|...   .  | |..|||.||..|||..| .. .|.  ..  . .|.   . ..| .||..|. ..|. ....|      
liqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallalles-leaeekvdvfqvvkklrkarplmvsveeqyillydvlve

Phosphatase PTPRN.AA Subfamily.N_Choan_2.PD 733-969 34 2.4e-51 165.6 In-house 20-264 (266) Show / Hide
Range on Protein: 733-969
Range on HMM: 20-264/266
Sequence Identity: 34% (83 aa)

GNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGASLY
| . ||. | ||  ..|..|. ... |.. ||||  .   | .  .|||..|||  |. .||.|.||.  | |||.|.|.|.| |.|.|||| |  .  .
rnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekv

HV--YEVNLVSEHIWCE-DFLVRSFYLKNvqTQETRTLTQFHFLSWPAEGTPASTR------PLLDFRRKVNKCYR--GRSCPIIVHCSDGAGRTGTYIL
.   ... ....   |  ....   |..   .|||.|. |.. .|| .| | ..        ||.  |.|...   .. |..||||.| ||||| |.||.
kladgkikvlalseekeegyiltrlrlek--kgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtlia

IDMVLNRMAKGvKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEE
... . .  |..|..| .|..| .|. ||.  .|.|..  ||.|    
iDiavrlLeet-kkvdvlaiieelRkdRmalvqhpeqyellykavvey

Phosphatase PTPRN.AA Subfamily.N_Nematode_4.PD 721-968 31 1.6e-45 146.7 In-house 13-261 (264) Show / Hide
Range on Protein: 721-968
Range on HMM: 13-261/264
Sequence Identity: 31% (79 aa)

AEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKvESSPSRsDYINASPIIEhdPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQC
.| ....   | | .|||. | |  |..|. || . .|.. ||| || .    |    ||.|||||..|..||| ||..  ..|.|||  |.|.||..| 
kappnvtasaseknsdknryadilcidetrvvlk-nrdpdn-dyihaswmrm--PdkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekc

DRYWPDEGAS--LYHVYEVNLVSEHIW-CEDFLVRSFYLKNVQ-TQETRT----LTQFHFLSWPAEGTPASTRPLLDFRRKVNKcyRGRSCPIIVHCSDG
||.|..      .  |...|| ..     | ...|. . |.. .... .    .  ...  |. . .|  ..|.... . |.|  . .. ||.|||| | 
aryypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaG

AGRTGTYILIDMVlNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
||| |.. ||.  . . . . ||..   . ..|  | . |.|. || | |..|   
vGrtatlvGidya-tirirenseievldivrelramrlkavqshlqflfllvvlie

Phosphatase PTPRN.AA Subfamily.N20.PD 726-968 36 9.6e-44 141.1 In-house 18-254 (257) Show / Hide
Range on Protein: 726-968
Range on HMM: 18-254/257
Sequence Identity: 36% (88 aa)

CATAQGEGNIKKNRHPDFLPYDHARIKLKVEsspsrSDYINASPI-IEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYW
. .   | .|||. | |||| .|. |         |||||| | |        ||||||||  || |||||| |  . || |.|  .| |..| .|||  
fnsgnqpsnreknryrdilpydstrvplgks-----kdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhyw

PDEGASLYHV--YEVNLVSEHIwCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRgrSCPIIVHCSDGAGRTGTYILI
      .  . | |   .|  . |..| | . .  |  .... |..|  ||  |||||.  .. . |   |..   . |..|||| | |||| .. .|.|
pislkkplelkhfrvflenyqi-lqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshl--tgpmvvhcsagigrtgvflcv

DMVLNRMAKGVkEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
.  . | .  ..|   . ..|.|| |.|..|.|. |.   | |   
dvvfcaivknc-sfnimdivaqmreqrsgmvqtkeqyhfcydivle

Phosphatase PTPRN.AA Subfamily.N_Nematode_1.PD 709-961 30 5.6e-38 121.9 In-house 2-255 (265) Show / Hide
Range on Protein: 709-961
Range on HMM: 2-255/265
Sequence Identity: 30% (78 aa)

LAKEWQALCAYQAEPnTCATAQGEGNIKKNRHPDFLPYDHARIKLKVEssPSRSDYINASPIiEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVM
| .|..||  .. |  .  . . . . .|||. |    |..|.||. |  |. |||| |  .     .   .| .|.|| .|||||| ||       |||
lrdefralkkfndee-kvkafkeaqeadknrykdvgcldknrvklaee--plpsdyihanyv-gtptnpkrficaqaPldktiadfwymvlqekveaivm

LTPLVEDGVKQCDRYWPDEGASLYHVYEV--------NLVSEHIWCEDFLVRSFYLKNVQ-TQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVnkcyR
|  |.| | |.|  |.| .  .  .. |         .| ....  ..  ..   |.     ..||..|....  ||  | |.     |..  .|    |
lckliekgkkkcaeyfpakegeklefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleav----r

GRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEF
|   ||.|||| | ||||| . |...|.....| .  |.   ....|.||...  |. |   
gskgPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylf

Phosphatase PTPRN.AA PTPc_motif 866-968 35 1.2e-37 132.28 SMART 1-92 (92) Show / Hide
Range on Protein: 866-968
Range on HMM: 1-92/92
Sequence Identity: 35% (38 aa)

TLTQFHFLSWPAE-----GTPASTRPLLDFRRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFE
|....|...||       |.|    ..|.|.|.|.|       ||.||||.|.|||||...|||....       .||  |....|.||||.| ...|. 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ-------VDIFQTVKEMRKQRPGMVQTEEQYI

FALTAVAE
|   ...|
FCYRCILE

Phosphatase PTPRN.AA Subfamily.R_Nematode_3.PD 728-968 21 4.1e-37 119.1 In-house 21-264 (267) Show / Hide
Range on Protein: 728-968
Range on HMM: 21-264/267
Sequence Identity: 21% (53 aa)

TaqgeGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEhdPRMPAYIATQGPL--------SHTIADFWQMVWESGCTVIVMLTPLVE---DG
.     .....|. ... . . |..||   .   .|.|.|. .    |     | ||.|.          ||  ||.|. . ....|||   ||   ...
s----kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvec--pnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgee

VKQCDRYWPDEGASLYHVYEVNLVS---EHIWCEDFLVRSFYLkNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYrgrsCPIIVHCSDGA
..| .|.|..     .. .|..     ..   ||.  |.. . ... ... | |  .. .|.....|.....|.  ..|.|.      |..|||||| .|
eekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfveksk----tpvvVHCsdGi

GRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
..|   |... . ..|  ...|... ....| ||.| . .. .. |... .    
sRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilk

Phosphatase PTPRN.AA Subfamily.R_Nematode_2.PD 729-961 27 4.5e-36 115.6 In-house 24-251 (261) Show / Hide
Range on Protein: 729-961
Range on HMM: 24-251/261
Sequence Identity: 27% (62 aa)

AQGEGNIKKNRHPDFLPYDHARIKLKVESspSRSDyINASPIIEhDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEG
.  |.|.||    ...... .|.    |.. | |  .   . .   .|||||||. |  ||| ||    .  ||||.||   ..|..|.| |  .  .  
saaylpkdkhRypdvPCkpetavevivdg--krvp-ihanwvpt-agnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfplet

ASLYH--VYEVNLVS-EHIWCEDFLVRSFYLKNVQT-QETRTLTQFHFLSWPAEGTPASTRPLLdfrrKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDM
 .... || |.|  ..  .|..  .. .   .|||.| . . .||..|.| |   |.. .  ..   ||.|||| | |||...| .... ... .  ..|
sqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelf----eLlelvkksekPivvhCsaGiGRtmafigtey

VLNRMAKgVKEIDIAATLEHVRDQRPGLVRSKDQFEF
 .. .|...|..|.  .. . |. .            
larevea-dptieltealkelrehRwkgiqtesqlyw

Phosphatase PTPRN.AA Subfamily.N_Nematode_5.PD 722-967 27 5.1e-35 112.1 In-house 13-254 (258) Show / Hide
Range on Protein: 722-967
Range on HMM: 13-254/258
Sequence Identity: 27% (67 aa)

EPNTCATAQGEGNIKKNRHPDFLPYDHARIklKVESSPsrSDYINASPIIEHDPRMpAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPlVEDGVKQCD
||.. . . | |.||||..|.  .|. |.  |..  .  ..||||| |   | .   .| || ||..|..|||.|| .  .|.|.|..  |.  ..   .
kpnketckafeknlkknrskdvkilDetrV--kltded--dsYinaskiklddlek-kliltQlPlpdteedFWrmvyqekitsvvllve-deelketav

RYWPDEGASlYHVYEVNLVSEHIWCEDFLV-RSFYLKNVQT--QETRTLTQFHFLSWPAEGTPASTRPLLD-FRRKVNKCYRGRSCPIIVHCSDGAGRTG
.|.|  . |  ..  ..      ..      .... .     |   ..  |.  |. .  |... ...     || . . |.. |..|... |.||.|| 
sffpletgd-ylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvsdlGlgRag

TYILIDMVLNRMAKGvKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVA
.|.... . . .| ||..|...|...|.|||| | | .|. .. .||.  
tflllsvaieqlnng-kepnideilkkirsqRpgavesliqyasvyaavl

Phosphatase PTPRN.AA Subfamily.N_Nematode_6.PD 719-968 28 9.3e-34 108.2 In-house 6-250 (253) Show / Hide
Range on Protein: 719-968
Range on HMM: 6-250/253
Sequence Identity: 28% (72 aa)

YQAEPNTCATAQGE---GNIKKNRHPDFLPYDHARIKLKVESspsrSDYINASpIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVED
|.. ||.... . .   .. ..||...   .| .|.||. .       || |. ...  ..   .| ||.||  || .||.|.|| . ||||  |||.| 
ykdspneaseseataflkfkdrnrytniqCcdagrlkladde----dfyihan-lvkistkprrlictqaplegtieefwkmilssgveyivmlcelvek

GVKQCDRYWPDEGASLYHVYEV-NLV-SEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRgrscPIIVHCSDGA
... .| .|.     .. .. . .  ..   .  ||||      ...|   .  .|. .||  | ||    | .   | |. .    ||.|||| | |||
gkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvkkdkk----PivvhCsaGv

GRTGTYILIDMVLNRMAKgVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAE
|| .|| ..|. . . .. ...   | ..|..|   |. . |. .||| |     
GrtGtlaliliilealrl-pdfqgvkdllvklreerfravqtevqylyalrcvle

Phosphatase PTPRN.AA Subfamily.N_Fungi_PTP1.PD 733-858 32 5e-26 82.6 In-house 44-182 (343) Show / Hide
Range on Protein: 733-858
Range on HMM: 44-182/343
Sequence Identity: 32% (44 aa)

GNIKKNRHPDFLPYDHARIKLK--------VESSPSRSDYINASPII------EHDPRMpAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVK
|||. . |||.|.|.|||        .. | | .|||||. .       | .|    |||||.||  |. ||.... . ..||..||..|| ....|.||
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdf-kYiatqaPlpstvddfykvillnkvkvilsltsdvelnle

QCDRYWPDEGASLYHVYEVNLVSEHIWCEDFLVRSFYLKN
|.. . . ..|   .   . .  .|   .|. .|.     
kcyrYWqegsydditvklaskwenimgindsslysadvkk

Phosphatase PTPRN.AA Subfamily.N_Nematode_egg.PD 726-961 23 7.2e-24 75.8 In-house 18-247 (257) Show / Hide
Range on Protein: 726-961
Range on HMM: 18-247/257
Sequence Identity: 23% (56 aa)

CATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASpIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDgvKQCDRYWP
||  . . .| | .     . .|.||...      |.| |   .. .| .  .| .| ||  |  |||.||..  .  |||||  .|   ..|. |||  
lttaasdnylekarskrvhckessrvklelrrGqylddfihan-rvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyywp

DEGASLYHVYEVNLVSE--HI-WCEDFLVRSFYLKNVQTQETRTLTQfhFLSWPAEGTPASTRPLldfrrKVNKCYRGRSCPIIVHCSDGAGRTGTYILI
 .    .   .|  |  ..    | | |   || | ...     .     .  . .     ||     .| .  |  | |..|.. .|  ...| . |..
kaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelfle--hwqgdvnylsdvyspl-----rvlrklrnlskpvvvqdilGvskaatlvai

DMVLNRMAKG-VKEIDIAATLEHVRDQRPGLVRSKDQFEF
 | .. .| .    .  .   .| .|.  | |  .. |  
eiallsllrGpitkslvlravvflrlrrrlsvesvllylf

Phosphatase PTPRN.AA Subfamily.N_Nematode_eak.PD 727-883 25 4.8e-19 59.9 In-house 19-172 (281) Show / Hide
Range on Protein: 727-883
Range on HMM: 19-172/281
Sequence Identity: 25% (40 aa)

ATAQGEGNIKKNRHPDFLPYDHARIKLKvESSPSRSDYINASpIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPD
..   ....||  . .|.|.  ..|   |   |  ||||| ..|       || |  .  . .  ||||| |     ||.|   || .... |.|.||..
rvtarleavnrnrvvkivpqdrylvrlt-ssqlnrdGyinas-laefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpd

EGASL-YHVYEVNLVSEHIWCEDFLVRSFYLKnvQTQETRTLTQFHFLSWPAEGTPAS
  | | ...|.  .  .  . . .| . |.  . .||  .  ...  |    .|    
ktevlkyGildverkeyavkrniletrllilr--kGnethrvlhykvfGwtettlpky

Phosphatase PTPRN.AA Subfamily.N_Fungi_PTP1.PD 898-961 36 5.9e-10 29.8 In-house 256-333 (343) Show / Hide
Range on Protein: 898-961
Range on HMM: 256-333/343
Sequence Identity: 36% (27 aa)

YRGRSCPIIVHCSDGAGRTGTYILIDMVLN------RMAKGVKEIDIA--------ATLEHVRDQRPGLVRSKDQFEF
|| ||.|||| | |||||.. .|..|.       . |  ...| |         .. ..| ||  .|...||| |   
dnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfif

Phosphatase PTPRN.AA Family.DSP.PD 797-961 18 1.9e-09 28.5 In-house 128-238 (387) Show / Hide
Range on Protein: 797-961
Range on HMM: 128-238/387
Sequence Identity: 18% (31 aa)

MvWESGCTVIVMLTplvedgvkqcdrywpdegaslyhvyevnlvsehiwcedflvrsfylKNvQTQETRtLTQFHFLSWPAEGTPASTRPLLdFRRKVNK
.  | | |.|| ||                                              .. ..|.|    ....| .| . ..|..  .| | ... .
l-kelgvtkivnlt----------------------------------------------dd-kpqftk-elgikylripidDhnapplenl-fekaidf

CYRGR--SCPIIVHCSDGAGRTGTYILIDMVLNrmakgvKEIDIAATLEHVRDQRPGLVRSKDQFEF
  |.  .  . |||  | ||.|| | . .. .      . .   ..|..||..||| .. ...|   
ieegndskgvVlVHCkaGkgRsgtliiaYlmks------egltleealdwvrskRpgvitpnqgflk

Phosphatase PTPRN.AA Subfamily.PTPDC1.PD 872-961 26 8.8e-08 23.0 In-house 139-219 (229) Show / Hide
Range on Protein: 872-961
Range on HMM: 139-219/229
Sequence Identity: 26% (23 aa)

FLSWPAEGTPaSTRPLLDFRRKVNKCYrgRSCPIIVHCSDGAGRTGTYILIDMVLNrmakgvKEIDIAATLEHVRDQRPGLVRSKDQFEF
...  |.. |   .||  . |.     .   | |||  | ||||  |   .| .      |... .  .. ||..||  .....| |.  
nfglkDygva-sleriLdivkvvdfal--eegkiavHCHAGlGRtGvliacylvya------krltaeeaiklvrskrpksiqtreqvel

Phosphatase PTPRN.AA Subfamily.DSP23.PD 892-958 25 5.4e-06 17.7 In-house 57-116 (128) Show / Hide
Range on Protein: 892-958
Range on HMM: 57-116/128
Sequence Identity: 25% (17 aa)

RKVNKCYRgRSCPIIVHCSDGAGRTGTYILIDMVLNRmakgvkEIDIAATLEHVRDQRPGLVRSKDQ
| |.. .. .  .. |||  | ||||| .   .| ..      ..  . ..  || .|.| . ...|
riveeaek-keeavgvhcalGlGrtGtllacylvkee------glaaddaiaevrkrrkGsietveq

Sequence
Name Sequence Type Origin Length Description Download
PTPRN.AA Protein None 979 None Fasta, JSON
PTPRN.NA RNA None 2937 None Fasta, JSON
PTPRN.AA.PD_708-971 Protein Phosphatase Domain None 264 None Fasta, JSON