Gene PTEN
PTEN
Species: Human
Alias: BZS, PTEN1, MHAM, MMAC1, 10q23del, PTEN, MGC11227, TEP1
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PTEN.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PTEN.AA | PTPc_motif | 23-183 | 12 | 8.4e-07 | 26.64 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 23-183
Range on HMM: 1-92/92
Sequence Identity: 12% (21 aa)
LDLTYIYPNIIAM-----GFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDN
| |.| . | | |....|... .|
TVHHYHYTNWPDHVEKDSGVPE-----------DSILEFIRHVRK-------------------------------------------------------
HVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLK
.|| || ||||.......... | . |. . . . |.. | .|.
-PIVVHCSAGCGRTGTFCAIDMMMQQ-------VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCILE
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| Phosphatase | PTEN.AA | Subfamily.PTEN.PD | 24-347 | 38 | 1.3e-89 | 291.8 | In-house | 1-303 (305) | Show / Hide |
Range on Protein: 24-347 Range on HMM: 1-303/305 Sequence Identity: 38% (127 aa) DLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIH |..||..|.|....|.|..|.....|..|....|....|...|...|.|........|..|||.|||.|||||.|||.....||.|.||.||...|.|.| disyilvnlivlsypvetyekllyrnslddlillltvykgkgklrilnargekedsdfdgrvavypfdDhnpptleLleeivedvdkwLkedksnVvavH CKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETipmfSGGTCNPQFVVCQLKVK |||||||||||||||||..|.. .|.|||..|.|.||.||||||||||||||.|.|.|.|. . | |.| .. | || .| | . | |. CkaGkGRtGvmicayLlksgikksadealaiydekRtkdkkGVtiPSQrRYvqYfsklvkssvpyskvslnvceirfse----sscvqnlgmvecsisvl IYSS--NSGPTRREDKFM------YFEFPQPLPVCGDIKVEFFHKQNkmlkKDKMFHFWVNTFFipgpeetsekVENGSLCDQeiDsiCSIeradndkEY |. | | . . . .||.||.|.|. .| . |||.|||| || | |. | .. . . || hdsatenakpdrlktlpidfqksfvltikpsipvsgdvkfeltkksp----dkiichfwlntff----------vrnyspces--d--gtv-------nk LVLTLTKNDLDKANKDKANRYFSPNFKVKLYF .|...| .|| .. || .||. . | yihtlskseiddvhkdsehkrfseefkisivf |
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| Phosphatase | PTEN.AA | PTEN_C2 | 188-349 | 29 | 2.1e-51 | 181.87 | Pfam | 1-141 (141) | Show / Hide |
Range on Protein: 188-349 Range on HMM: 1-141/141 Sequence Identity: 29% (50 aa) YRPVALLFHKMMF-ETIPMF-SGGTC-NPQFVVCQLKVKI---YSSNSGPTRR-EDKFMYFEFPQPLPVCGDIKVEFFHKQ-NK--MLKKDKMFHFWVNT . |..| .|.... ..||.| .||.| .|.. . | ..|. .... ..... ..| ..|.||||.||.||.|....||. .. ......||.|| || PPPKPLFLHCIIMDHGIPNFKQGGGCWRPYIQIYQNDQKVFYTCKKYWHCKKYKQQKCCIFKFPQPCPVQGDVKIQCYHKGPSDLPWMYEECMFRFWFNT FFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTK .||.. .. .||..||.||||.|||... |.|.|||...|.. CFIEH-------------------------------NNNRLTFPKNELDKAWKDKKWKRFPPDFKVEVVFSE |
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| Phosphatase | PTEN.AA | Family.DSP.PD | 26-300 | 25 | 5.4e-43 | 139.0 | In-house | 95-363 (387) | Show / Hide |
Range on Protein: 26-300 Range on HMM: 95-363/387 Sequence Identity: 25% (71 aa) TYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIkpFCEDLDqWLSE--DDNHVAAIH || . .. | | | |...| . ... . |.... || ||. ... | . . .. ..|..|||.|.||.. |....| ...| |...|...| tydhfervengkpseilphlylgsllaaknlewlkelgvtkivnltddkpqftkelgikylripidDhnapplenl--fekaid-fieegndskgvVlVH CKAGKGRTGVMICAYLLHRgKFLKAQEALDFYGEVRtrdkKGVTIPSQRrYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQF--VVCQLK |||||||.|..|.|||... . |...||||.. ..| .||..|.|. .. ... |.|. | . . ..... . .. . . ..| .|.| CkaGkgRsgtliiaYlmks-egltleealdwvrskR----pgvitpnqg-flkqlkdlekeklkvssevmelrfvissivqnlgsvevsvsvlkkvatek VKIYSSNSGPTRREDKFMyFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEI . .. .|.. . ||. ||.|||.|.| . .| .. .. .| .|. .| | | ..| akldrlkiLvideqekvv-itikdglplsgDVkvelfkknldkiirdiilntfFvtnyikdeslvlvkkeldelhkski |
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| Phosphatase | PTEN.AA | Subfamily.TPIP.PD | 81-281 | 36 | 2.4e-38 | 123.4 | In-house | 1-210 (245) | Show / Hide |
Range on Protein: 81-281 Range on HMM: 1-210/245 Sequence Identity: 36% (76 aa) FNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDK-----KGVTIPSQRRYV |. || . .||| |.|| . |......||..| ..| ||||| |||||| ..||.|.. . ||.|.|.||..|| || . .|||||.||| | fhnrvsrimiddhnvPtleelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliaseifltaeesldyfgerrtdkthsnkfqGvetPsqnryv YYYSYLLKN-HLDYRPVALLFHKMMFetIPMFSGGTCNPQFVVCQLKVKIYSSNS-GPT-----RREDKFMYFEFPQPlPVCGDIKVEFFHKQNKMLKKD . . . . | .|| | . | | |. . | | ..|| | | . || . . | |. |.||.|| . . gylaqvkhlynwnlpprrilfikrfi--iysirgdvcdlkvqvvmekkvvfsstslgncsilhdietdkilinvydgp-plyddvkvqffssnlpkyydn KMFHFWVNTFFIP | ||.|| || cpfffwfntsfiq |
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| Phosphatase | PTEN.AA | Subfamily.Tensin.PD | 81-289 | 32 | 1.8e-32 | 104.0 | In-house | 1-213 (237) | Show / Hide |
Range on Protein: 81-289 Range on HMM: 1-213/237 Sequence Identity: 32% (69 aa) FNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKK--GVTIPSQRRYVYYY .| .| .. . |. | || . |. |. ||. | ..| ..||| ||||.||.|.||. . |..||| . | |.| |||||||||| |.| lnekvldlGWPdllaPpleklcsickalesWlkadpqnvvvlhckGgkGrigvvisaymhyskisasadaaldrfalkrfyddkvsgvtqPsqrryveyf SYLLKNHLDYRPVALLFHKMMFETIPMF-SGGTCNPQFVVCQLKVKIYSSNSGPTR-REDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVN ||.. . |..| .....|| | |.|.|.| . . | .|.| . . . . | . ||. |..||. . ..| .| | sgllsgsiklnssplflhyvilhgipnfdskggcrpflkiyqalqlvytsgvynvagedterlcitiepalllkgdvlvkcyhkklrsttrdvvfrvqfh TFFIPGPEETSEK | . . . || tgaikdlklvfek |
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| Phosphatase | PTEN.AA | Subfamily.PRL.PD | 52-161 | 27 | 9.3e-15 | 46.0 | In-house | 13-120 (140) | Show / Hide |
Range on Protein: 52-161 Range on HMM: 13-120/140 Sequence Identity: 27% (30 aa) DVVRFLDSKHKNHYKIYNLCAERHYDTAKF---NCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGkfLKA | .|.. .|.. | . | ||..|. . .| ...|.| ..| |... . | | . .|..... |.|| || ||. |... |.| .| ..| tvekfieelkkenvkevvrvcepsydaeklkeegievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalalieaG--mky QEALDFygeVRTR ..| .|.. edavef---irek |
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| Phosphatase | PTEN.AA | Subfamily.CDC14.PD | 38-174 | 28 | 1.2e-12 | 39.3 | In-house | 136-250 (258) | Show / Hide |
Range on Protein: 38-174 Range on HMM: 136-250/258 Sequence Identity: 28% (39 aa) PAERLEGVYRNNIDDVVRfLDSKhknhykiynLCAERHYDTAKFNCrvAQYPFEDHNPPQLELIKPFCEDLDQWlseddNHVAAIHCKAGKGRTGVMICA | . || .||. ..|| |..| | ..... | |. |.| |. ...| | | ... . .|.|||||||||..| .| Peklleyfrknnvttivr-Lnkk---------lYdakkftdaGfah--lDlffiDGtvPsdailkkfleiteka-----eGaiavhCkaGLGrtgtligc YLLHRGKFlKAQEALDFYGEVRtrdkKGVTIPSQRRY |... .| .|.|.. . .| | | |. | ylikhyrf-taaetiawlriar----PGsvigpqqty |
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| Phosphatase | PTEN.AA | Subfamily.DSP11.PD | 52-160 | 25 | 1.5e-12 | 38.8 | In-house | 10-123 (141) | Show / Hide |
Range on Protein: 52-160 Range on HMM: 10-123/141 Sequence Identity: 25% (29 aa) DVVRFLDSKHKNHYKIYNLC-AERHYDTAKFNCRVAQY---PFEDHNPPQLELIKPFCEDLDQWL--SEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKF |... |..|.|. . .| ..|.|.. ... . .| |. |. | .| |.| ....| ..|.... ..|| | ||| .||||... . dlleklqeknkklGLvidltntdryykkkeltdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegy lKAQEALDFYGEVRT ....|.. . |.| -spedaieafeearG |
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| Phosphatase | PTEN.AA | Subfamily.PTPDC1.PD | 85-172 | 31 | 8.6e-12 | 36.2 | In-house | 137-217 (229) | Show / Hide |
Range on Protein: 85-172 Range on HMM: 137-217/229 Sequence Identity: 31% (27 aa) VAQYPFEDHNPPQLELIKPFCEDLDQWLsedDNHVAAIHCKAGKGRTGVMICAYLLHRGKfLKAQEALDFygeVRTRDKKGVTIPSQR . .....|.. . || | .|. | . |.|| ||.|||||.|..||.. . |.|.||... || . | . .| fynfglkDygvasleriLdivkvvdfal---eegkiavHCHAGlGRtGvliacylvyakr-ltaeeaikl---vrskrpksiqtreqv |
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| Phosphatase | PTEN.AA | Subfamily.DSP23.PD | 82-179 | 27 | 2.3e-11 | 35.2 | In-house | 33-124 (128) | Show / Hide |
Range on Protein: 82-179 Range on HMM: 33-124/128 Sequence Identity: 27% (26 aa) NCRVAQYPFEDHNPPQLELIKPFCEDLDQwlSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKfLKAQEALdfyGEVRTRDKKGVTIPSQRRYVYYYS . . . .|. || || .. . . ... .|. . ..|| | |||| .. ||.. . | |..|. ||| | | . |. | | sltlrridipdfcPPaleqvarlvrivee--aekkeeavgvhcalGlGrtGtllacylvkeeg-laaddai---aevrkrrkGsietveqekavkdye |
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| Phosphatase | PTEN.AA | Subfamily.RNGTT.PD | 71-160 | 23 | 6.5e-10 | 30.2 | In-house | 29-121 (140) | Show / Hide |
Range on Protein: 71-160 Range on HMM: 29-121/140 Sequence Identity: 23% (21 aa) CAERHYDTAKF---NCRVAQYPFEDH-NPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFlKAQEALDFYGEVRT ..|.|| .. ... . . . . |. | .| | . ...|.. ..| ..|| | ||| .|.|||... .. . ..|.. . .| ntsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedw-sveaavalfakarp |
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| Phosphatase | PTEN.AA | Subfamily.R_Anemone_2.PD | 54-182 | 22 | 6.6e-10 | 30.3 | In-house | 129-258 (262) | Show / Hide |
Range on Protein: 54-182 Range on HMM: 129-258/262 Sequence Identity: 22% (30 aa) VRFLDSKHKNHYKIYNLCAERHYDTAKfnCRVAQYP---FEDHNPPQ--LELIKpFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYL-LHRgkfLK | .... ..| . .. .|. .. | |. . |.. |. .|.. . . ... | .... ..|| || |||||| |.| .|| velkeevelsdyvlrsfkvkrteeeee--rqvrqfhytsWpdegvpesgaslld-lvrqvekaqqesgagpivvhcsaGvGrtGvfiavdiller---ik AQEALDFYGEVRT-RDKKGVTIPSQRRYVYYYSYLL .. .| .. |.. |... . . . .|.. | || aealvdvfqtvkqlreqrnlmvqtkdqyefiydvll |
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| Phosphatase | PTEN.AA | Subfamily.PTPMT1.PD | 45-160 | 25 | 1.8e-09 | 28.8 | In-house | 21-128 (146) | Show / Hide |
Range on Protein: 45-160 Range on HMM: 21-128/146 Sequence Identity: 25% (29 aa) VYRNNIDDVVRFldskhKNHYKIYNLCAERHyDTAKFNCRVAQYPFEDHNP-PQLELIKPFCEDLDQWLSEDDnHVaAIHCKAGKGRTGVMICAYLLHRG |. .|. || . . |.. .|. . . . | . |.. |. |.|| .. | ... |. . | .|||||..| ... .||... | vekenvkavvsl-----neeyelkalanste-ewkklGveqlqlatvDfteapslekleegvefiekvaskgs-sv-YvHCkAGrtRsatlvacylmkkk KfLKAQEALDFYGEVRT |...|| .| . | k-lspeeavkflkkkRp |
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| Phosphatase | PTEN.AA | Subfamily.R_Sponge_2.PD | 53-181 | 21 | 2.3e-09 | 28.4 | In-house | 127-257 (262) | Show / Hide |
Range on Protein: 53-181 Range on HMM: 127-257/262 Sequence Identity: 21% (28 aa) VVRFLDSKHKNHYKIYNLCAERHYDtAKFNCRVAQYPF----EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHrgKFLKA .| . .... ..|.| .| .. . . |.|. | |. | . . . ... . .. |.. ..|..| |||||. . . . ||| | kvtlkeeekladyiirklklskeks-segeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfialdsvl--erlka QEALDFYGEVRT-RDKKGVTIPSQRRYVYYYSYL .| . ..| | |. . . .||. . | eeeidvfevlktlrtkriglvqdaaqYvfihdal |
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| Phosphatase | PTEN.AA | Subfamily.N5_RR.PD | 37-180 | 19 | 4.3e-09 | 27.4 | In-house | 114-259 (265) | Show / Hide |
Range on Protein: 37-180 Range on HMM: 114-259/265 Sequence Identity: 19% (28 aa) FPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKfNCRVAQYP-FEDHN-PPQLELIKPFCEDLDQWLSEDDNHVA--AIHCKAGKGRTG || .. . . .| ... . ...|.|.. .| . . . .. |. . ||. | . . . .... .. .|.....| .|| || |||| fPdaedyeiserygdveikveeiverndysvrklvlkylerver-svkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtG VMICAYLLHRgkFLKAQEALDFYGEV-RTRDKKGVTIPSQRRYVYYYSY ..|.. . | |.... .| . | . | ..| . .. .| . . cfiaisiavr--qlreeivvdvlkivcnlrldrGGmvqtseqyelihra |
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| Phosphatase | PTEN.AA | Subfamily.RB.PD | 54-182 | 21 | 1.7e-08 | 25.5 | In-house | 129-257 (261) | Show / Hide |
Range on Protein: 54-182 Range on HMM: 129-257/261 Sequence Identity: 21% (29 aa) VRFLDSKHKNHYKIYNLCAERHYDtakfNCRVAQY---PFEDHNPP-QLELIKPFCEDLDQWLSED-DNHVAAIHCKAGKGRTGVMICAYLLHrgKFLKA | | .|..... | .. |.. . . .| || . ||. | . . . |.. ........ .. .|| || ||||. | |. ..... vtllaekeldewvirefkiekgke----krkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrll--qaiee QEALDFYGEVR-TRDKKGVTIPSQRRYVYYYSYLL .| .| | | .. . . ....|.. .. || ndyvdvfgvvaelReeRnllvqtekqyifihecll |
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| Phosphatase | PTEN.AA | Subfamily.RK.PD | 92-182 | 19 | 1.1e-07 | 22.6 | In-house | 172-263 (267) | Show / Hide |
Range on Protein: 92-182 Range on HMM: 172-263/267 Sequence Identity: 19% (18 aa) DH--NPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHrgKFLKAQEALDFYGEVRT-RDKKGVTIPSQRRYVYYYSYLL .. | . . . . .... .|... .|| || ||.|. | . . .. .. .| . |.| |..| . . .|.. | | eyrdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtfiaidivl--emieregvvdvfnavktlrnrkvnmveteeqykfvydvil |
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| Phosphatase | PTEN.AA | Subfamily.R_Ecdysozoa.PD | 53-183 | 20 | 2.1e-07 | 21.7 | In-house | 127-266 (269) | Show / Hide |
Range on Protein: 53-183 Range on HMM: 127-266/269 Sequence Identity: 20% (29 aa) VVRFLDSKHKNHYKIYNLCAERHY-DTAKFNCRVAQYPFEDHN-----PPQLELIKPFCEDLDQWLSED----DNHVAAIHCKAGKGRTGVMICAYLLHR .|.. .......| | .| . .. . . .| || . . | . . . . | . . . . . .||.||||.|.... || lvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgrsgifvaldlllq GkfLKAQEALDFYGEVRT-RDKKGVTIPSQRRYVYYYSYLLK ||| . .| . |. | .. . . | ..||. | |.. q--lkaedkvdifetvkkLrsqrnllvqsleqyvflyralad |
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| Phosphatase | PTEN.AA | Subfamily.RA.PD | 113-182 | 30 | 2.4e-07 | 21.7 | In-house | 194-262 (266) | Show / Hide |
Range on Protein: 113-182 Range on HMM: 194-262/266 Sequence Identity: 30% (21 aa) SEDDNHVAAIHCKAGKGRTGVMICAYLLHrgKFLKAQEALDFYGEVR-TRDKKGVTIPSQRRYVYYYSYLL . || ..|| || |||| .| . . .||.. || .. |. | .. . .. .|.. | || qqsanhpivvhcsaGvGrtGtfivldavl--ervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvll |
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| Phosphatase | PTEN.AA | Subfamily.R_Anemone_1.PD | 104-183 | 19 | 3.4e-07 | 21.5 | In-house | 178-255 (258) | Show / Hide |
Range on Protein: 104-183 Range on HMM: 178-255/258 Sequence Identity: 19% (16 aa) FCEDLDQWlSEDDNHVAAIHCKAGKGRTGVMICAYLLH-RgkfLKAQEALDFYGEV-RTRDKKGVTIPSQRRYVYYYSYLLK . ... . |. ... .|| || ||||. . . . . .|... .| . | . | .. .. .. .||. .. .|. lrrkvqks-slagarpvvvhCsaGvgRtGaflvidamleq---akkekvvDifnyvkairedrphmvqtkeqyvfihlavle |
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| Phosphatase | PTEN.AA | Subfamily.N12.PD | 92-178 | 25 | 9.8e-07 | 19.4 | In-house | 174-262 (270) | Show / Hide |
Range on Protein: 92-178 Range on HMM: 174-262/270 Sequence Identity: 25% (23 aa) DHNPPQ-LELIKPFCEDLDQWLSeDDNHVAAIHCKAGKGRTGVMICA-YLLHRGKFLKAQEALDFYGEVRT-RDKKGVTIPSQRRYVYYY ||. |. . . . |.. . . .... ..|| || ||||..| | . | | .| || . | . | .. . .. .|.. | DhgvPssaksllelielvrelqe-sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvy |
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| Phosphatase | PTEN.AA | Subfamily.N14.PD | 100-182 | 22 | 1.5e-06 | 18.9 | In-house | 188-271 (275) | Show / Hide |
Range on Protein: 100-182 Range on HMM: 188-271/275 Sequence Identity: 22% (19 aa) LIKPFCEDLDQWLS--EDDNHVAAIHCKAGKGRTGVMICAYLLHrgKFLKAQEALDFYGEVR-TRDKKGVTIPSQRRYVYYYSYLL .. .. .. . .. . .|| || |||||.| . || . |. .| .| .. | .. . ... .| . |. |. evqsvrrktnsevesvkeskPPvlvhCsaGvGrtGvlilsdlli--atlehneeidikkvlarLrkqrmllvqtlaqykfvykvli |
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| Phosphatase | PTEN.AA | Subfamily.N13.PD | 92-181 | 24 | 2.6e-06 | 18.4 | In-house | 167-254 (259) | Show / Hide |
Range on Protein: 92-181 Range on HMM: 167-254/259 Sequence Identity: 24% (23 aa) DHNPPQ--LELIKpFCEDLDQwLSEdDNHVAAIHCKAGKGRTGVMICAYLLhrGKFLKAQEALDFYGEVRT-RDKKGVTIPSQRRYVYYYSYL ||. |. ||.. | .. . | . |. ..|| || ||.||.|. . . .. .. .| ||. |... . .. .|.. | . dhgvPssaaelvq-fvaevrl-lqt-dagPivvhcsaGiGrsGvlitidvv--lglierdkefdvkeivrklreqrqgvvqtkdqyifvykai |
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| Phosphatase | PTEN.AA | Subfamily.N6.PD | 55-176 | 22 | 3.7e-06 | 17.7 | In-house | 158-285 (295) | Show / Hide |
Range on Protein: 55-176 Range on HMM: 158-285/295 Sequence Identity: 22% (28 aa) RFLDSKHKNHYKIYNLCAErHYDTAKFNCRVAQYPFE---DHNPP-QLELIKPFCEDLDQWLSED-DNHVAAIHCKAGKGRTGVMIC-AYLLHRGKFLKA . .. |....|.. .. . | |. | . .. || |. ||. | . . . | ||... .| .. .|| || |||| .| .|.. ... tsisEkstadYtlRefsvs-hkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgl QEALDFYGEVRT-RDKKGVTIPSQRRYVY .|.. ... | .. . .. | . dvdidisksikdvrsqrsglvqteaqykf |
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| Phosphatase | PTEN.AA | Subfamily.DSP19.PD | 110-154 | 29 | 5.4e-06 | 17.6 | In-house | 74-115 (139) | Show / Hide |
Range on Protein: 110-154 Range on HMM: 74-115/139 Sequence Identity: 29% (13 aa) QWLSEDdnHVAAIHCKAGKGRTGVMICAYLLHrGKFLKAQEALDF . .|.| . .||.|| |. .. |||.. . |. ..||. earskd--grvlvHCnAGvSRsasvviaylmk-deelslekalek |
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| Phosphatase | PTEN.AA | Subfamily.N_Choan_1.PD | 103-182 | 26 | 5.8e-06 | 17.2 | In-house | 179-258 (262) | Show / Hide |
Range on Protein: 103-182 Range on HMM: 179-258/262 Sequence Identity: 26% (21 aa) PFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRgKFLKAQEALDFYGEVRT-RDKKGVTIPSQRRYVYYYSYLL | ... . ... .. ||| || ||||. | | . . . .|||| |. | .. . . . .| . | .| efrkavlkatkkktkaplvihCsaGvGrtGtyialDrlvk-aveekaealdvkavvaelrkernlmvqtlvqyefvykavl |
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