Gene ILKAP
ILKAP
Species: Human
Alias: FLJ10181, MGC4846, ILKAP, PP2C-DELTA, DKFZp434J2031
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of ILKAP.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | ILKAP.AA | Group.PPM.PD | 89-390 | 36 | 1.5e-90 | 294.1 | In-house | 20-321 (459) | Show / Hide |
Range on Protein: 89-390 Range on HMM: 20-321/459 Sequence Identity: 36% (112 aa) SEELVEKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITEECrppsslitrvSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISVE---- . .|... . .. . ||. ||...|.|.||.|.||| ... ... |.|.||||||| .|..|||..|...| ....| . .. ||. dqasaehhlessagsgnglrygvasmqgwrkemEDrhvivenfdnnd----------sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksae ---------KTVKRCLLDTFKHTDEEFLKQASSQK-PAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNeesqkhAALSLSKEHNPTQYEERMRIQKA .| ..|. .||.. ..|.... | .. |.||...| .. ||.||.|||||.||| . | |||.|.|.. |||||.|||| |. |||.|.|. asldnddrgekvkkalrsafleldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrng------kavplskdHkpenpeEreRIeka GGNVRD-GRVLGVLEVSRSIGDGQYKRcG---VTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDekiqtreGKSAADARYEAACNRL |||..|| ..|. . |.. ||.. ..||..|.|. ||.|||. |...||.|.|. . ||. |. ...|....||...|...||. gGsveidgRvnGilavsRalGdhdlkk-eeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlek-------kkkelkkdleeiaerl ANKAVQRGSA------DNVTVMVVRI ||.||.||.. vdealakgstgdgtscDNiTvivvtl |
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| Phosphatase | ILKAP.AA | Subfamily.ILKAP.PD | 103-388 | 62 | 5.1e-142 | 462.6 | In-house | 5-298 (298) | Show / Hide |
Range on Protein: 103-388 Range on HMM: 5-298/298 Sequence Identity: 62% (182 aa) VIFGLKGYVAERKGEREEMQDAHVILNDITEECRPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISVEKTVKRCLLDTFKHTDEEF .. |.|..||||||||||.||||||||..|..| ..| ..||||.||||||.| |||.|||..||.....|.|| || . .|..|.||.|.||.|||||| skyklegafaerkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeef LKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQK-----HAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQ |.||..||.|||||||..||.|||.||.||||||.|.|.|..||..| .|...|||.|.|..||||.|||||||.|||||||||||||||||||.. lklaskakPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGvlevsRsiGDgr YKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDE---KIQTREGKSAADARYEAACNRLANKAVQRGSADNVTVMVV |..||.| ||...|.||.||.|..||||||.|||. .|.|.|||..|||| ||...|||||...|.|.||.|||..||.|||.|||||..| fkelgvistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlededdrkikqeegksaeevrfevacerlAseavkrgssDnvtvllv |
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| Phosphatase | ILKAP.AA | PP2Cc | 94-388 | 24 | 2.4e-95 | 323.99 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 94-388
Range on HMM: 1-338/338
Sequence Identity: 24% (94 aa)
EKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITEECRPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISVE---------
. ....|....|. .. ...| |..|.||||. . .|.||||||| .........||..|.. .. . . .
HS-MGYNSGWRYGY--MESSMQGWRHPMEDAHVCRP-----------------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEP
------------KTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKH-----AALSLSKEHNPTQYEE
. ....| ..|. .|||. .||...| ..| ||.||.|||||.||| ... ... |. |...|.| . .|
EMWWRMWHDKWFEDWEDALRKAFLRMDEEI--------------CTAVVALIRGNKLYVANVGDSRAVLCRNGND-NWWGIRHYTAHQLTEDHKPDNEDE
RMRIQKAGG--------NVRDG-----RVLGV---LEVSRSIGDGQYKR-----------------------CGVTSVPDIRRCQL------TPNDRFIL
| ||..||| |... ||.|| |.|||..||..||. ..|...||. ..| || |.|..
RRRIEQAGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLI
LACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKSAADA------------RYEAACNRLANKAVQRGSADNVTVMVV
|.||||. |....|.| .. .||. .. . .. |... ...|..||...| ||.||.||
LCCDGLWDVMSNQEVVDIVRKCLRKWHHK-PVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----CDNMTVIVV
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| Phosphatase | ILKAP.AA | Family.PPM.PD | 102-389 | 37 | 2.5e-84 | 273.6 | In-house | 10-285 (495) | Show / Hide |
Range on Protein: 102-389 Range on HMM: 10-285/495 Sequence Identity: 37% (112 aa) SVIFGLKGYVAERKGEREEMQDAHVILNDITEECrppsslitRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISV-------EKTVKRCLLDT | ..||. ||. .|.|.||.||||..... .. ..|.|.||||||| .|..|||..||..|... | | .. ||..| .. sssnglrygvasmqgwrsemeDahvvvenlenne--------dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrka FKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNeesqkhAALSLSKEHNPTQYEERMRIQKAGGNVRD--GRVLGVLEVSRS |. .|||. ........ .. |.||..|| .. ||.||.|||||.||| . | |||.|.|.. ||| ||.||||.|. ||||||.|||.. fleldeelseelneksagkdsGtTAvvvlirgkklyvAnaGDsravLcrng------kavelskdHkpenpeEreRIekagGkvvirdgrvnGvlavsRa IGDGQYKR---CGVTSVPDIRRCQLTPN-DRFILLACDGLFKVFTPEEAVNFILSCLedekiqtregkSAADARYEAACNRLANKAVQRGSADNVTVMVV || ..|. ..|...|||. ..||.. |.|. ||.|||. |...||.|... . | . ....|.....| ..|...|| ||.||.|| lGdfdlkkeeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretl-----------eekeedleeiaeeLvdealakgsrDNiTvlvv R a |
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| Phosphatase | ILKAP.AA | PP2C | 107-383 | 31 | 4e-69 | 240.77 | Pfam | 1-284 (284) | Show / Hide |
Range on Protein: 107-383 Range on HMM: 1-284/284 Sequence Identity: 31% (95 aa) LKGYVAERKGEREEMQDAHVILNDITEECRPPSSLITRVSYFAVFDGHGGIRASKFAAQNLH----QNLIRKFPKGDV-ISVEKTVKRCLLDTFKH--TD . . . . | |..| |||..... . || ...|||||||||..|.|.....|| . | .. . . | |...| ..| || WDYGFCRMQGWRHFMEDAHHCYPNMNCS----SSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNP---KDVEQALRKSFLECDTD EEFLK---QASS--QKPAWKDGSTATCVLAVDNI--LYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVR---DGRVLGV-LE ..| . . . . |. |.||.|.. ... ||.||.|||||.||| .. . |.. | |. .|| ||..||| | .|| || |. MMFYSAPWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNW--VHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLA VSRSIGDGQYKR--------CGVTSVPDIR-RCQLTPN-DRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKSAADARYEAACNRLANKAVQRG |||..|| .|| ..||..||| ..|| | |..||||||. | ...|.. .. .|..|.. .. ||..|.......| VSRAFGDFHYKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWN------------DPMEACEKLVDYCIAYG SADNV | ||. SEDNI |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1A.PD | 110-389 | 32 | 7.3e-61 | 196.1 | In-house | 13-277 (309) | Show / Hide |
Range on Protein: 110-389 Range on HMM: 13-277/309 Sequence Identity: 32% (94 aa) YVAERKGEREEMQDAHVILNDITEEcrppsslITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRK--FPKGDVISVEKTVKRCLLDTFKHTDEEFLKQAS ... .| | || |||.. |.... . |.|||||||.| ..||..|..|....... | .. | ...|| | ..| ..||. |... glssmqgwRvemEDahtavidlpsk-------lkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekirklve SQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNeesqkhAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRC------ .| . | ||||..|| .. ||.||.|||||.|.| . .. ...| |.. .|. ||..||| | .|| | | |||..|| .||. lskgedksGsTavvvlvspkklylancGDsRavlsrng------kvvfateDHkpsdpkEkeRienAgGsvmikRvnGsLAvsRalGDydykekpekkat --GVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEdekiqtregksaADARYEAACNRLANKAVQRGSADNVTVMVVR |.. |... .. . .| |..|||||.. | . ||...|. | || . . |...|.| ......|| ||..|..| eqlvspepevtvierdeedeflvlacDGiwDvmsneevaefvksrle------------vtddleevanelldtcLekgsrDNmsvilvl |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1E.PD | 113-388 | 36 | 2.3e-57 | 184.4 | In-house | 17-267 (269) | Show / Hide |
Range on Protein: 113-388 Range on HMM: 17-267/269 Sequence Identity: 36% (102 aa) ERKGEREEMQDAHVILNDITEECRPpsSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGD--VisvektvkRCLLDTFKHTDEEFLKQAssQK |..| | | ||.|.|. | . . ..|||||||||. |.|.||..||..|.|. . . . | ..||.|||||..| .. .. avknkrrkmEDrhvaledlnelfel--kdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa--------ealkeafkltDerflqka--er PAWKDGSTATCVLAVDNILYIANLGDSRAILCRyneesqKHAALSLSKEHNPTQYEERMRIQKAGGNVR---DGRVLGVLEVSRSIGDGQYKRCgVTSVP | |||| .|| . ||.| ||||.|.|.| | |..| | |.| . .|. ||..||| | || ||| |||.||| ..|. |.. .|. eklksGstavvvliekdqlyvaWlGDsqallvr------kgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklkpy-vsgea DIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQtregksaadarYEAACNRLANKAVQRGSADNVTVMVV ...|. .. ...||||||. |...||.|. . . |.|.. . .. . . | ..| ..||.||.||.|| dvaeveldgsedylilacDGlwDvvneeevvklveefladgaed-----------lsevakllveaakeagssDnitvvvv |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1G2.PD | 115-350 | 34 | 4.4e-53 | 170.3 | In-house | 18-243 (275) | Show / Hide |
Range on Protein: 115-350 Range on HMM: 18-243/275 Sequence Identity: 34% (84 aa) KGEREEMQDAHVILNDITEECRPPsslitRVSYFAVFDGHGGIRASKFAAQNLHQNLIRkfpkGDV-IsvEKTVKRCLLDTFKHTDEEFLKQASSQKpaW .| | .| |||.. |.. |. . ....||||||||| ...|.|...|.. . . | .....| |.|..||||.||. . .. qGyrlnmeDahilenelleksddk-----slalfavfDGhGGakvakyagkklikkiak----kksfk--egaleqilkdafletDeellkdeklkd--e KDGSTATCVLAVDNILYIANLGDSRAILCRYNEesqkhaALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCG--------VTS . ||||. || .. ||.|| |||||.|. . . .|| .| |.. .|. ||..||| | .|| |.| .||..|| ..|.. || saGstavvvlikeeklyvanaGDsravlsskgn------vkalsfDhkPqeesekkriiaagGfvelnrvngnLalsralgDfefkknvkkkpeeqivta VPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKI |||. .|...| |..|||||.. |.| .| |... . | ... vPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgak |
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| Phosphatase | ILKAP.AA | Subfamily.LRR-PP2C.PD | 112-390 | 29 | 4.9e-45 | 144.0 | In-house | 15-257 (257) | Show / Hide |
Range on Protein: 112-390 Range on HMM: 15-257/257 Sequence Identity: 29% (84 aa) AERKGEREEMQDAHVILNDITEECRppSslitrvSYFAVFDGHGGIRASKFAAQNLHQNLIRKfpkgdvISVEKT-VKRCLLDTFKHTDEEFlkqasSQK .. | | |.| || .. . |.|.|||||| .|.|||...|.. | . . .... ...| ...|... . |.. sdmiGrrptmedelviyGsfrdksd--e------dyyalfdGhgGraaakfaseelykilael------ldlnnanPlkslkkaykeistqi-----ser PaWKDGSTATCVLAVDNILYIANLGDSRAILCryneeSQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDG----RVLGVLEVSRSIGDgQYKRCGVTSV | |.||. || ... ||||.||||..|| .. | || .|.|.. .|. ||...||.| . || | | |||..|| . |.. p-kfiGttaasvliiedkvyianvGdsrvvlc-----qkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGd-sflePfvvpd PDIR-RCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKiqtregksaadaryeaACNRLANKAVQRGSADNVTVMVVRI ||. . . .|.|..|||||.. . . ||||. ... . || |...| ..| ..|| ||..|.|... PdlsqsleiskkdkflilacdGiwdlisdeeaveivagisdpek----------------aaeklrdlayssGstdnisvivikl |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1L.PD | 115-389 | 34 | 1.4e-40 | 129.6 | In-house | 20-272 (273) | Show / Hide |
Range on Protein: 115-389
Range on HMM: 20-272/273
Sequence Identity: 34% (98 aa)
KGEREEMQDAHVILNDITEEcrppssliTRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVI---SVEKTVKRCLLDTFKHTDEEFLKQASSQKP
.| |..|.| | .||... | |.||||||||| |..|| . | ... .|. . | .| . .. | | ||..|..| ...
lGrrprmedrfeieediknk--------tgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekakraed
awKDGSTATCVLAVDNILYIANLGDSRAILCryneeSQKHAALSLSKEHNPTQYEERMRIQKAGGNVR---DGRVLGVLEVSRSIGDGQYKRCG-VTSVP
|.|| | .. | .||.|||| .|. .. |. || .| | | .|| ||.|||| . || ||| .||..|| | | . |
--iaGttalialvqesdlivanvGdsrGvly-----dkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkdknlviadp
DIRRCQLTP-NDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQTregKSaadaryeaacnrLANKAVQRGSADNVTVMVVR
|| .| . .|..||.|||. |. ||||.||. |.. .. . || |. .. .|||||.||.||.
diltfdlddhkpeflilasdGlwdtfsneeavrfikerlkepdfGa---ks------------lvlesfkrGsvdnitvlvvk
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| Phosphatase | ILKAP.AA | Subfamily.PPM1K.PD | 143-389 | 32 | 1.4e-39 | 126.1 | In-house | 35-263 (264) | Show / Hide |
Range on Protein: 143-389 Range on HMM: 35-263/264 Sequence Identity: 32% (81 aa) TRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKgdvisvEKTVKRCLLDTFKHTDEEFLKQA---SSQKPAWKDGSTATCVLAVDN-ILYIANLGDSR . |||||||||| | |. ..|.. . | ..| || ... | . |. |... . . ... . |.||| .| | |.|.|||||||| pdllyfavfdGhgGssaadfvhdkleeivrrllek------ekdleevlkqafeeldkklkrylefsvaeaellssGttatvsllrdGnelvlaslGdsr AILCRYNEesqkhaALSLSKEHNPTQYEERMRIQKAGGNVR-----DGRVLGVLEVSRSIGDGQYKRCGVTSVPDIRRCQL-TPNDRFILLACDGLFKVF || . | |.|.|.| . ||. ||..|||.| .| ..| ..||.|| . || || . |. .. ...| |..| ||. | . .| ailcrnGk------akkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkryGviatPetkslkvkhaadsflvlitdgisfvv TPEEAVNFILSCLEDEKiqtregksaadaryeaACNRLANKAVQRGSADNVTVMVVR ... | . |. | . ....|.| || ||.|..|| nsqelcdlvrlchdpee----------------aahavteqalqygsednatavvvp |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1G.PD | 207-389 | 35 | 1.8e-37 | 119.7 | In-house | 299-481 (482) | Show / Hide |
Range on Protein: 207-389 Range on HMM: 299-481/482 Sequence Identity: 35% (68 aa) SSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYneesqkHAALSLSKEHNPTQYEERMRIQKAGGNVR-DGRVLGVLEVSRSIGDGQYKRC---- .|..| |.||. | .. |..|| ||||..|.| || || .| | .|. ||.||||.| |||| | | .|| .||||. kseepGkdsGttavvaLvkgkklivanaGDsRcvlsrn------GkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeLp ----GVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQtregKSAADARYEAACNRLANKAVQRGS-ADNVTVMVVR .. .|||. ||..| |. |||||.. | . .| |.|. . |.... . |. .. | . ||.. |.||.||..|. aeeqmisalPDikklilteedeFlvlacDGiWnvmssqevvdFvraklkesees----kklseiceeLlDaCLapdtsgDGtGCDnmtvvivq |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1D.PD | 111-281 | 28 | 6.1e-30 | 94.6 | In-house | 12-180 (311) | Show / Hide |
Range on Protein: 111-281
Range on HMM: 12-180/311
Sequence Identity: 28% (48 aa)
VAERKGEREEMQDAHVILNDITEECRppsslITRVSYFAVFDGHGGIRASKFAAQNLHQNLIR--KFPKGDVISVEKTVKRCLLDTFKHTDEEFLKQASS
.. ..|.|. |.| .| . .| . . ...|||||||| |.||| ..| ... . || . .| . ... |.| ... . . ..
seadqGgrkymeDvvaivlereesae-----eaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpkt
-QKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDG
|.||..|. . ||.|. |||...| ... .| | | |.| | . ||. ||...||.| .
ksgllstaGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaak
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| Phosphatase | ILKAP.AA | Subfamily.PDP.PD | 183-299 | 30 | 6.2e-18 | 55.4 | In-house | 123-254 (409) | Show / Hide |
Range on Protein: 183-299
Range on HMM: 123-254/409
Sequence Identity: 30% (39 aa)
VEKTVKRCLLDTFKHTDEEFLKQASSQ--KPA--------WKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQkHAALSLSKEHNPTQYEERMRIQ
|..|.. | .|.. |... ..| .. . |..|...| .. |..|| ||.||.|.. .||.. . | .|||... .|| ||.|.
kelkveealkkaFlrlDkdislealkkleekvleeavlkvalsGacallaliegtelhvAntGDcravlgvqeeegs-weavkLskdqtadneeEveRik
KAG---GN---VRDGRVLGVLEVSRSIGDGQYK
. .|.||.|| | .| || .||
keHPgeesktvirngRlLgeLaPlRAFGdvryK
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| Phosphatase | ILKAP.AA | Subfamily.TAB1.PD | 214-330 | 35 | 1.8e-16 | 50.1 | In-house | 136-267 (336) | Show / Hide |
Range on Protein: 214-330 Range on HMM: 136-267/336 Sequence Identity: 35% (42 aa) KDGSTATCVLAVDNILYIANLGDSRAILCRYNEESqkHAALSLSKEHNPTQYEERMRIQKAG---GNVRDGRVLGVLEVSRSIGDGQYKRC--------- ..|.|| .| . | ||.||.|||||||.. ... . || .|| .| |... | .... ..|| | ||||| . |. . |||. . sgGttavvalilnnkLyvaNvGdsrAilvesekdg--ikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykikkgykevdvlss ----GVTSVPDIRRCQLTPNDR-FILLACDGLFK .. . |.|| |||.| AkgePiiatPdingpkdindlegfllLmSdGlyk |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1H.PD | 179-273 | 35 | 8.8e-14 | 41.2 | In-house | 130-214 (402) | Show / Hide |
Range on Protein: 179-273 Range on HMM: 130-214/402 Sequence Identity: 35% (33 aa) DVISVEKTVKRCLLDTFKHTDEEFLKQASSQKpaWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEEsqkhaaLSLSKEHNPTQyeERMRIQK || |. |. | . |.. || .. .. . | | || .| ... ||.|| |||||||.| .| ||... | |||.|. kkiskeeLviGalesaflemDeqiarereayr--ikGGCtalvalvllgklYvanaGDsRailvrkdei------iplsadftPet--eRqRlqe |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1D.PD | 287-388 | 36 | 6.8e-13 | 38.6 | In-house | 207-311 (311) | Show / Hide |
Range on Protein: 287-388 Range on HMM: 207-311/311 Sequence Identity: 36% (39 aa) LEVSRSIGD-----GQYKRCGVTSVPDIRRCQLTPNDR-FILLACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKSAADARYEAACNRLANKAVQrgsA | |.||.|| . .. | .||. .|.||.. ||.|| |||..| |||.||... . | .... ...| | | . | .| ..| .. | LavaRslGDlWsynaksgeyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealqrwrskklr---a DNVTVMVV |||.|.|| Dnvsvivv |
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| Phosphatase | ILKAP.AA | Subfamily.PDP.PD | 303-361 | 29 | 2.5e-10 | 30.3 | In-house | 284-342 (409) | Show / Hide |
Range on Protein: 303-361 Range on HMM: 284-342/409 Sequence Identity: 29% (17 aa) VTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKSAADA .|. |.. .|..||.|..|| |||. ....||.|. . |...| .. ...|. ltaePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkknkakvaaepakl |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1G.PD | 115-206 | 30 | 7e-10 | 28.8 | In-house | 18-94 (482) | Show / Hide |
Range on Protein: 115-206 Range on HMM: 18-94/482 Sequence Identity: 30% (28 aa) KGEREEMQDAHVILNDITEECrppsslitrvSYFAVFDGHGGIRASKFAAQNLHQNLirkfpKGDVISVEKTVKRCLLDTFKHTDEEFLKQA .| |..| ||| . |..|.. | |||.||||| .|..|..| . | | .. | |...| ..| . |...|... qGWRvsmeDahncildldedt----------slfavyDGhGGkevakycakklPdll-----keskaykegdvekaleeaflkvDkklltee |
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| Phosphatase | ILKAP.AA | Subfamily.PHLPP.PD | 229-341 | 29 | 3.4e-08 | 23.0 | In-house | 119-226 (257) | Show / Hide |
Range on Protein: 229-341 Range on HMM: 119-226/257 Sequence Identity: 29% (34 aa) LYIANLGDSRAILCRYNEesqkhaALSLSKEHNPTQY-EERMRIQKAGGNV-RDGRVLGVLEVSRSIGDgQYKRCGVTSVPDIRRCQLTPNDRFILLACD | || |. ...|.| | ||| . . || ||..| . . |..| ||.| .| .| . | | .| .||..| ...| . ltaanvgkcklvlirnGk------plplskvyileiddeelkrikeakaiitednkvnGviestrilGy-tflfPvvlPkphvrsvlLteqdEllilGnk GLFKVFTPEEAVNFI .|..|. .|||. . alWevlsideaveav |
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| Phosphatase | ILKAP.AA | Subfamily.TAB1.PD | 147-205 | 30 | 9.7e-08 | 21.4 | In-house | 38-93 (336) | Show / Hide |
Range on Protein: 147-205 Range on HMM: 38-93/336 Sequence Identity: 30% (18 aa) YFAVFDGHGGIRASKFAAQNLHQNLIrkfpKGDVI-SVEKTVKRCLLDTFKHTDEEFLKQ .|||||. | .|..|..|.| ..|. .||. . | ..|. || .......|... lyavfdGydGekaaefveqrLvaell----lgdlseeaeaepkllllqvieeverkffes |
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| Phosphatase | ILKAP.AA | Family.PPTC7.PD | 148-243 | 26 | 5e-07 | 19.8 | In-house | 37-128 (262) | Show / Hide |
Range on Protein: 148-243 Range on HMM: 37-128/262 Sequence Identity: 26% (26 aa) FAVFDGHGGIRASKFAAQNLHQNLIRKFPKGdVIsvekTVKRCLLDTFKHTDEEFLKQASSQKPawKDGSTATCVLAV---DNILYIANLGDSRAILCR ..| || || | . .. ..|..| . | . | . | . | .. . . .....| . ||. ||... |. |. ||||||. | lgvADgvggwreygvdssafsselmkkcerl-vk----eskfkplkpkkllkaayaelleekvp--vvGsstAcvvvldredkklesanlGDsgflvvR |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1H.PD | 144-175 | 41 | 5.1e-07 | 18.9 | In-house | 63-94 (402) | Show / Hide |
Range on Protein: 144-175 Range on HMM: 63-94/402 Sequence Identity: 41% (13 aa) RVSYFAVFDGHGGIRASKFAAQNLHQNLIRKF . ||..||||.| |. |...||. | .|. playfglfDGhaGsgaalvaskllhkhlkekl |
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| Phosphatase | ILKAP.AA | Subfamily.PPM1H.PD | 276-388 | 23 | 6.4e-07 | 18.6 | In-house | 272-402 (402) | Show / Hide |
Range on Protein: 276-388 Range on HMM: 272-402/402 Sequence Identity: 23% (30 aa) GNVRDGRVLGVLEVSRSIGDGQYKRCGV--------TSVPDIRRCQLTP----NDRFILLACDGLFKVFTPEEAVNFILSCLEDE-KIQTREGKSAADA- |. . |.|. . |.| .|| . | . ..||..| .|| .| ..|| |||. | . ||. . . . |.. . .....| . gegkkaRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvdsedkkrytavaqeL ----RYEAACNRLANKAVQRGSADNVTVMVV | . . | . .| |...|.|. vaaarGklkdkgWrlkeekaasvDDisvfvi |
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| Phosphatase | ILKAP.AA | Subfamily.PPTC7.PD | 148-245 | 22 | 9.4e-07 | 18.9 | In-house | 38-131 (263) | Show / Hide |
Range on Protein: 148-245 Range on HMM: 38-131/263 Sequence Identity: 22% (23 aa) FAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVisvekTVKRCLLDTFKHTDEEFLKQASSQKPawKDGSTATCVLAVDNI---LYIANLGDSRAILCRY ..| || || | . .. ..|..| . . | . .. | .. . . .....| . ||. .|....|. |. |||||| . | lgVADgvggwreygidpsefskelmkkcerivk-----eskfkerkpkkileaayqelleekvp--vvGsstacivvldredkklesaNlGDSgflVvRn N . g |
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| Phosphatase | ILKAP.AA | Subfamily.PDP.PD | 139-189 | 25 | 2.9e-06 | 17.0 | In-house | 31-82 (409) | Show / Hide |
Range on Protein: 139-189 Range on HMM: 31-82/409 Sequence Identity: 25% (13 aa) SSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKF-PKGDVISVEKTVKR ..| .. |.||||||| ... ..| . . . .| .. ..|...| kllesngvlfgvfDGHggaacaeavskrLlkyvaasllkkqvlleaeeaeks |
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