PP2D1
Species: Human
Alias: PP2D1
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPM
Family: PPM
Subfamily: PP2D1
Protein domain

Protein domains of PP2D1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase PP2D1.AA Group.PPM.PD 162-624 33 1.7e-81 264.1 In-house 28-324 (459) Show / Hide
Range on Protein: 162-624
Range on HMM: 28-324/459
Sequence Identity: 33% (101 aa)

K-ICHLLIKGVGICEDRNSTWKADMNDKFTVVSNFGNKPnvCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTTDEQQIINSFytvfREeya
..  ..|.... . .. |...|.|....|.||.|..  .|||.||||.||.|||... .||  |..||.| . .......|..  |.     |.|. .||
lessagsgnglrygvasmqgwrkemEDrhvivenfdnnd--sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldndd----rg---

aiedlfsainkteavrceyEDTHKAFAKAFWRMDRLLGLGRKEVS-RVQWSGCSAVTCILEgkpkspyahknwkrknthdglaesspsqempkiiSGILH
. .||...|. |  ...| . ....||..||...... |.|||.|. .||||||||  .|.|.|...| .||.|| ..|  .   .     |.|.....|
-------------------ekvkkalrsafleldedlseeanekeepgkdsGtTAvvalin----------------------------------gkkly

VANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISS-NepygLVEGQVKTTRGLGFhgnLKLKKS---IIPAPQTISVPIDDLCQFLIVATN
.||.    .|||.   ... |.. .|......||..|..|||.||..|||  ....|....|. .. ..| .. .||..|| .||.      |||||.|.
vANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidg----RvnGilavsRalGd---hdlkkeeqmvsaePdvsvvklteedeflvlAsD

GLWEVLDKEEVTALAMTTFHMyketycpiipnkspskgpllfstsepnltksqsnihvlfqyksvsevrvsttnskenlsdsnyskyciynpenvetfpa
.||..                                                                                               
GlWdvlsneevvefvretlek-------------------------------------------------------------------------------

etthrkpcsekvtdrptsvndvatnekesdTKSFYEGAAEYVSHELVNAALLAGSR------DNITVMVIFLNGS
                                                                           
------------------------------kkkelkkdleeiaerlvdealakgstgdgtscDNiTvivvtlnda

Phosphatase PP2D1.AA Family.PPM.PD 168-624 33 1.1e-81 264.7 In-house 12-289 (495) Show / Hide
Range on Protein: 168-624
Range on HMM: 12-289/495
Sequence Identity: 33% (106 aa)

IKGVGICEDRNSTWKADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTTDEQQIinsfytvfreeyaaiedlfs
..|.... . .. |...|.|...||.|..|......||.||||.||.|||... .|.  |..||.| | ....|..|..|. ..|. |||...|. |  .
snglrygvasmqgwrsemeDahvvvenlennedfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessa--------------------

ainkteavrceyEDTHKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEG-KpkspyahknwkrknthdglaesspsqempkiisgiLHVANTGNV
..|.|....||..||.....| |                                   |.|||.|. .||||||||  .|.|.|...|..||.|| ..| 
------------ekvkealrkafleldeelseelneksagkdsGtTAvvvlirgkk-----------------------------------lyvAnaGDs

QAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSnePYGLVEGQVKTTRGLGFhgnLKLKK----SIIPAPQTISVPID-DLCQFLIVATNGLWEVL
 ...  . | |.|.....|.||.    .|||    .... |.. ||... . ..||..|..|||.||..|||  |...|.. .| ..| ...|||..|| 
ravLcrngkavelskdHkpenpeEreRIekagGkvvi--rdgrvnGvlavsRalGd---fdlkkeeqaivsaePditsvkltqeedeflvlasdGlWdvl

DKEEVTALAMTTFhmyketycpiipnkspskgpllfstsepnltksqsnihvlfqyksvsevrvsttnskenlsdsnyskyciynpenvetfpaetthrk
.||||||||.|..|...                                                                                   
sneevvelvretl---------------------------------------------------------------------------------------

pcsekvtdrptsvndvatnekesdtkSFYEGAAEYVSHELVNAALLAGSRDNITVMVIFLNGS
                                                               
--------------------------eekeedleeiaeeLvdealakgsrDNiTvlvvalyen

Phosphatase PP2D1.AA Subfamily.PPM1A.PD 172-475 24 6.2e-30 94.4 In-house 13-246 (309) Show / Hide
Range on Protein: 172-475
Range on HMM: 13-246/309
Sequence Identity: 24% (59 aa)

GICEDRNstWKADMNDKFTVVSNFGN-KPNVCFFGLFDGHHGASAAELTSMELPVLLLHQlSKFDpsyqmttdeqqiinsfytvfreeyaaiedlfsain
|. . ..  |.. | |..|.| .. .  ..  ||..|||| |..... .. .|   .|.. ..|... . . |....|. |.| ..|  .    .  .. 
glssmqg--wRvemEDahtavidlpsklkdwsffavfDGHaGskvskycakhlleailee-eefk-----------------------------------

kTEAVRCEYEDTHKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEgkpkspyahknwkrknthdglaesspsqempkiiSGILHVANTGNVQAVL
. ||. ||.....| .|| |   |||.||||    |..| . ...|..|| . |  .  .     |.|..  .| || .         . .. ..| |..
-askeksskekvkealrkgfLelDekirklvelskgedksGsTavvvlvs----------------------------------pkklylancGDsRavl

CRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEpyglVEGQVKTTRGLGFHGN------LKLKKSIIPAPQTISVPIDDLCQFLIVATNGLWEVLDKE
... .|.  .||..|. |.|.|...|||...  ....                                                               
srngkvvfateDHkpsdpkEkeRienAgGsvmikR----vnGsLAvsRalGDydykekpekkateqlvspepevtvierdeedeflvlacDGiwDvmsne

EVTALAMTTFH
           
evaefvksrle

Phosphatase PP2D1.AA PP2Cc 162-619 13 2.1e-26 94.99 SMART 1-338 (338) Show / Hide
Range on Protein: 162-619
Range on HMM: 1-338/338
Sequence Identity: 13% (71 aa)

KICHLLIKGVGICE--DRNSTWKADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQM----------TTDEQQIIN
.  . . .|.  .   ... .|.  | | . ..          |||.|||| | ..|.  .  |.  |. .|.. . ....           . .    .
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP---------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMW-W-R-MW

SFYTVFREEYAAIEDLFSAINKTEAVRCEYEDTHKAFAKAFWRMDRLLGLGRKEVSRVQWSGCSAVTCILEGKPKSPYAHKNWKRKNTHDGLAESSPSQE
     |.   .|... | ....                                        |.||.... |.                           
-HDKWFEDWEDALRKAFLRMDEEI--------------------------------------CTAVVALIRGNK--------------------------

MPKIISGILHVANTGNVQAVLCRNGK----------GFCLTKEHTTRNTNERRRILQNGA-------VISSNEPY--GLVEGQ---VKTTRGLGFHGNLK
        |.|||.|  .|||||||.             ||..|.  |  ||||| | |.          .|..     | |.      .| .| |   .
--------LYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKW

LK----------------------KSIIPAPQTISVPI------DDLCQFLIVATNGLWEVLDKEEVTALAMT---------------------TFHMYK
 |                        .|. |.. .. .      ..  .||| .. |||.|.. .||  ...                            
-KEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLWDVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMR-----

ETYCPIIPNKSPSKGPLLFSTSEPNLTKSQSNIHVLFQYKSVSEVRVSTTNSKENLSDSNYSKYCIYNPENVETFPAETTHRKPCSEKVTDRPTSVNDVA
                                                                                                    
----------------------------------------------------------------------------------------------------

TNEKESDTKSFYEGAAEYVSHELVNAALLAGSRDNITVMVI
     .   .   .... .. .|...|.    .||.||.|.
-----H-R-QKKHNDPMEAAKRLCDCAI----CDNMTVIVV

Phosphatase PP2D1.AA PP2C 310-466 26 8.2e-20 72.93 Pfam 114-250 (284) Show / Hide
Range on Protein: 310-466
Range on HMM: 114-250/284
Sequence Identity: 26% (45 aa)

SGCSAVTCILEGKPKSPYAHKNWKRKNTHDGLAESSPSQEMPKIISGILHVANTGNVQAVLCRNGKGF----CLTKEHTTRNTNERRRILQNGAVISSNE
|||.||.... .. .                                ||.||| |  .|||||||. .     ||. |.  |..||||| | |  ..   
SGCTAVCAYIRNQKN--------------------------------ILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWW-

PYGLVEGQ-VKTTRGLGFHGNLK------LKKSIIPAPQTI-SVPIDDL-CQFLIVATNGLWEVLDKEEV
  . | |. .  .| .|..  ..       .. ....|..  ...|..   .||| |. |||.|....||
GFWRVNGVWLAVSRAFGDFHYKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEV

Phosphatase PP2D1.AA Subfamily.PPM1E.PD 356-475 30 3.6e-19 59.0 In-house 121-236 (269) Show / Hide
Range on Protein: 356-475
Range on HMM: 121-236/269
Sequence Identity: 30% (36 aa)

GILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYgLVEGQVKTTRGLGfhgNLKLKKSIIPAPQTISVPIDDLCQFLIVATN
|.||  |. ||.|.|.|.   |.| |   . .|..|| ..| ..   . .  | |..  .| .|   . |||. ..  ... .|..|....||.|..|||
dqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigaw-RvnGvLsvsRaiG---DvklkpyvsgeadvaeveldgsedylilacD

GLWEVLDKEEVTALAMTTFH
.|...|||. |    ..   
GlwDvvneeevvklveefla

Phosphatase PP2D1.AA Subfamily.PPM1K.PD 358-469 34 6.2e-19 58.2 In-house 119-230 (264) Show / Hide
Range on Protein: 358-469
Range on HMM: 119-230/264
Sequence Identity: 34% (39 aa)

LHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSN-EPYGLVEGQVKTTRGLGfhgNLKLKKS-IIPAPQTISVPID-DLCQFLIVAT
| .|..|. .|.||||||  .|||.|.  ...|..||.. |  ...|     ||....  || ||   .|.||.. .|  |.| |. .. .||.. |.|.
lvlaslGdsrailcrnGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslG---dldlkryGviatPetkslkvkhaadsflvlit

NGLWEVLDKEEVTAL
  |....|.. |   
dgisfvvnsqelcdl

Phosphatase PP2D1.AA Subfamily.PHLPP.PD 355-467 32 2e-16 49.8 In-house 116-223 (257) Show / Hide
Range on Protein: 355-467
Range on HMM: 116-223/257
Sequence Identity: 32% (37 aa)

SGILHVANTGNVQAVLCRNGKGFCLTKEHTTRNT-NERRRILQNGAVISSNepyGLVEGQVKTTRGLGFhgnLKLKKSIIPAPQTISVPIDDLCQFLIVA
|. | .|| |. ..||.||||   |.| ..     .| .|| .. |.|  .   . |.| ...|| ||.     |  ...| |.  ||...   .||.  
sftltaanvgkcklvlirnGkplplskvyileiddeelkrikeakaiited---nkvnGviestrilGy---tflfPvvlPkphvrsvlLteqdEllilG

TNGLWEVLDKEEVT
..|||||. .|.. 
nkalWevlsideav

Phosphatase PP2D1.AA Subfamily.PPM1L.PD 358-470 34 2.4e-16 49.9 In-house 127-239 (273) Show / Hide
Range on Protein: 358-470
Range on HMM: 127-239/273
Sequence Identity: 34% (39 aa)

LHVANTGNVQAVLC-RNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYgLVEGQVKTTRGLGFHgNLKLKKSIIPAPQTISVPIDDL-CQFLIVATN
| ||| |. . ||. ..||   |. .|  .. .||.|| . |  |. .  .  |.| . |.| || .  || |. .|. |. ..  .||..|||.|..||
livanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvw-rvaGvlatsralGdy-plkdknlviadpdiltfdlddhkpeflilasd

GLWEVLDKEEVTALA
|. .  ||    .  
Glwdtfsneeavrfi

Phosphatase PP2D1.AA Subfamily.ILKAP.PD 353-480 25 2.9e-15 46.3 In-house 126-258 (298) Show / Hide
Range on Protein: 353-480
Range on HMM: 126-258/298
Sequence Identity: 25% (36 aa)

IISGILHVANTGNVQAVLCRN---GK--------GFCLTKEHTTRNTNERRRILQNGAVISSNEpyglVEGQVKTTRGLGfHGNLKLKKsIIPAPQTISV
..  .|.||| |. .|||.|.   |.          .|.|.||. . .||.|| . |.|.  .     | | ..  | .|  |. |    .|  |..  .
vvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgR----vlGvlevsRsiG-Dgrfkelg-vistPdvkkc

PIDDLCQFLIVATNGLWEVLDKEEVTALAMTTFHMYKET
 ...  .|...| .|||.|....||   .. ...  ...
eLtenDlfvvlaCDGLwkvfeadevvkfilkvlededdr

Phosphatase PP2D1.AA Subfamily.LRR-PP2C.PD 353-469 29 1e-13 41.2 In-house 108-223 (257) Show / Hide
Range on Protein: 353-469
Range on HMM: 108-223/257
Sequence Identity: 29% (34 aa)

IISGILHVANTGNVQAVLC-RNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYGLVEGQVKTTRGLGfhgNLKLKKSIIPAPQTI-SVPIDDLCQFL
||     .|| |. ..||| ..|    |. .|   . .|..|| . |  . |.     |.|..  .| ||   .  |.  ..| |.|. |    .|||.|
iiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralG---dsflePfvvpdPdlsqsleiskkdkfl

IVATNGLWEVLDKEEVTAL
 .|.|...  ||   .   
ilacdGiwdlisdeeavei

Phosphatase PP2D1.AA Subfamily.PPM1G.PD 357-468 33 4.9e-13 39.0 In-house 320-434 (482) Show / Hide
Range on Protein: 357-468
Range on HMM: 320-434/482
Sequence Identity: 33% (36 aa)

ILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNepyGLVEGQVKTTRGLGFHG-----NLKLKKSIIPA-PQTISVPIDDLCQFL
| ||| |.  .||.||||   |  .|   . .|..|| . |  .  .   | | | .   | || |      .| ..  .| | |. .  .||..|..|.
klivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvtld---gRvnGGLnlsRalGDhaYktneeLpaeeqmisalPDikklilteedeFl

IVATNGLWEVLDKEEVTA
| |.. .||         
vlacDGiWnvmssqevvd

Phosphatase PP2D1.AA Subfamily.PPM1G2.PD 356-472 30 9.3e-13 37.9 In-house 118-236 (275) Show / Hide
Range on Protein: 356-472
Range on HMM: 118-236/275
Sequence Identity: 30% (36 aa)

GILHVANTGNVQAVLCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEpyglVEGQVKTTRGLG---FHGNLKL--K-KSIIPAPQTISVPIDDLCQF
| |||.|. .|||. .|.   |. .|  ....|..|| ..| ... |     | |..   | ||   |  | |.  . . .   |  ..|.   ||..| 
eklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvelnr----vngnLalsralgDfefkknvkkkpeeqivtavPDvlvkkldeddef

LIVATNGLWEVLDKEEVTALAMT
.|.|.|| ..||  |  .     
lvLaCDGiWDvltnkevvdlvre

Phosphatase PP2D1.AA Subfamily.PDP.PD 200-396 21 3.5e-11 33.0 In-house 36-222 (409) Show / Hide
Range on Protein: 200-396
Range on HMM: 36-222/409
Sequence Identity: 21% (46 aa)

NVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTTDEQQII------NSFYTVFREEYAAIEDLFSA---INKTEAVRCEYEDTHKAFAKAF
| ..||.|||| || .||  | .|.  .  .| | .   ... .|...       .   .   . . . ..|. .    .  |..  . .....|  |||
ngvlfgvfDGHggaacaeavskrLlkyvaasllkkqvlleaeeaekslkellsilklekkpndsvlkeskklykeslkkyvqelleakelkveealkkaF

WRMDRLLGlgrKEVSR-VqwsgcsavtcilegkpkspyahKNWKRKNTHDGLAESSPSQEMPKIISGILHVANTGNVQAVLCR-NGKG----FCLTKEHT
 |.|. .    .|  . .                      .. . ...    | |     .  | .  |||||||  .|||.. ...|      |.|..|
lrlDkdis---lealkkl----------------------eekvleeavlkvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqt

TRNTNERRRILQ
..|..| .|| .
adneeEveRikk

Phosphatase PP2D1.AA Subfamily.PPM1L.PD 183-263 25 2.9e-09 26.7 In-house 24-99 (273) Show / Hide
Range on Protein: 183-263
Range on HMM: 24-99/273
Sequence Identity: 25% (20 aa)

ADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFdpsyqMTTDEQQIINSFYTVFREEYAAIE
|.|.|..  .  || .  ||..|||| |  ||| .   |.  ....| ..      .  |...  .| ... .|  ...  
prmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknkliel-----dadkentvpinfsklltdeilsvd

Phosphatase PP2D1.AA Subfamily.PPM1G.PD 180-230 26 1.1e-08 24.6 In-house 19-67 (482) Show / Hide
Range on Protein: 180-230
Range on HMM: 19-67/482
Sequence Identity: 26% (13 aa)

TWKADMNDKFTVVSNFGNkpNVCFFGLFDGHHGASAAELTSMELPVLLLHQ
|. .|.|  ... .. .  .. .|. .||| |.  |. .. .|| || .. 
GWRvsmeDahncildlde--dtslfavyDGhGGkevakycakklPdllkes

Phosphatase PP2D1.AA Subfamily.LRR-PP2C.PD 182-234 32 1.5e-08 24.3 In-house 21-73 (257) Show / Hide
Range on Protein: 182-234
Range on HMM: 21-73/257
Sequence Identity: 32% (17 aa)

KADMNDKFTVVSNFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKF
.. |.|....  .| .|..  .. ||||| | .||. .| ||. .| . |  .
rptmedelviyGsfrdksdedyyalfdGhgGraaakfaseelykilaelldln

Phosphatase PP2D1.AA Subfamily.PPM1H.PD 194-319 23 3.7e-08 22.5 In-house 57-174 (402) Show / Hide
Range on Protein: 194-319
Range on HMM: 57-174/402
Sequence Identity: 23% (29 aa)

NFGNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTTDEQQIINsfyTVFREEYAaieDLFSAINKTEAVRCEyEDTHKAFAKAFWRM
.  .| .. .||||||| | .|| ..|  |   | ..|..     . . .|.. ..   .  .|  .   .  .   . . .. | ||. .|| .|| ..
skeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellleksaeklalg---eerkeapt---epseifveekkiske-eLviGalesaflem

DRLLGLGRKEVsrVQWSGCSAVTCI-L
   |..    .  ||.|.  . |    
Deqiarereay--rikGGCtalvalvl

Phosphatase PP2D1.AA Subfamily.PPM1G2.PD 180-319 14 1.2e-07 21.1 In-house 19-115 (275) Show / Hide
Range on Protein: 180-319
Range on HMM: 19-115/275
Sequence Identity: 14% (19 aa)

TWKADMNDKFTV---VSNFGNKPNVCFFGLFDGHHGASAAELTSMElpvlllhqlskfdpsyqmttdeqqiinsfytvfreeyaaiedL-----Fsaink
.. .|.|  ..   . .  ..... .|..|||| ||..|. .. .                                          |. ...    ...
GyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkk------------------------------------------likkiak-----

teavRCEYE--DTHKAFAKAFWRMDRLLglGRKEVSRVQWSGCSAVTCIL
. .|| ..|. |   ..|  . . .|. ||. ..                
----kksfkegaleqilkdafletDeel--lkdeklkdesaGstavvvli

Phosphatase PP2D1.AA Subfamily.PPM1E.PD 184-237 28 1.9e-07 20.5 In-house 24-84 (269) Show / Hide
Range on Protein: 184-237
Range on HMM: 24-84/269
Sequence Identity: 28% (17 aa)

DMNDKFTVVSNF------GNKPNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKF-DPS
|.|.. .....       ....  ||. |||| |  ||. ....|. || .| .   ||  
kmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa

Phosphatase PP2D1.AA Subfamily.ILKAP.PD 183-253 20 3.6e-07 19.7 In-house 21-99 (298) Show / Hide
Range on Protein: 183-253
Range on HMM: 21-99/298
Sequence Identity: 20% (16 aa)

ADMNDKFTVVSNFGNK--------PNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTTDEQQIINSFYT
..|.|. ...... ..         .| ....|||| |  |.|..  .|   ....|.| | | . .. .. ....| .
eemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkk

Phosphatase PP2D1.AA Subfamily.PDP.PD 435-473 38 7e-07 18.8 In-house 287-325 (409) Show / Hide
Range on Protein: 435-473
Range on HMM: 287-325/409
Sequence Identity: 38% (14 aa)

APQTISVPIDDLCQFLIVATNGLWEVLDKEEVTALAMTT
|. .| ..    .||..|| |||..|..|||  | .   
ePevtshklrendkFLvlatDGLwdllsneevvslVgeh

Phosphatase PP2D1.AA Subfamily.PPM1D.PD 174-262 17 1.2e-06 17.9 In-house 11-96 (311) Show / Hide
Range on Protein: 174-262
Range on HMM: 11-96/311
Sequence Identity: 17% (16 aa)

CEDRNSTWKADMNDKFTVVS---NFGNKPNVCFFGLFDGHHGASAAELTSMELPVlLLHQLSKFdpsyqMTTDEQQIINSFYTVFREEYAAI
.   ..  .  |.| ...|.   . ... .  |...|||| |  ||. .. .|    ... .||     ..........     | .   |.
tseadqGgrkymeDvvaivlereesaeeaeaafvavfDGHGGkeAakfarehlws-vikkqkkf-----lssepedvleAireaflatheam

Phosphatase PP2D1.AA Subfamily.PPM1A.PD 592-624 41 1.4e-06 17.7 In-house 249-281 (309) Show / Hide
Range on Protein: 592-624
Range on HMM: 249-281/309
Sequence Identity: 41% (13 aa)

GAAEYVSHELVNAALLAGSRDNITVMVIFLNGS
.| |..||.. .|  |||||..|....|.|.  
ddleevanelldtcLekgsrDNmsvilvllpga

Phosphatase PP2D1.AA Subfamily.TAB1.PD 356-423 27 2.1e-06 16.8 In-house 149-219 (336) Show / Hide
Range on Protein: 356-423
Range on HMM: 149-219/336
Sequence Identity: 27% (19 aa)

GILHVANTGNVQAVLCRNG----KGFCLTKEHTTRNTNERRRILQNGAVISSNEPYGLVeGQVKTTRGLGFH
|.||| |. .|.|...     |   |  .|.. | .|  |. . |  |      ... |. ..|| .| .  
nkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrl-gskeaTRsiGdy

Phosphatase PP2D1.AA Subfamily.TAB1.PD 179-255 23 3.5e-06 16.1 In-house 18-90 (336) Show / Hide
Range on Protein: 179-255
Range on HMM: 18-90/336
Sequence Identity: 23% (18 aa)

STWKADMNDKFTVvsnfGNKPNVCFFGLFDGHHGASAAELTSMELPVLLL-HQLSKFDPSYQMTTDEqQIINSFYTVF
|. . ...||. .     .. ..  ...|||. | .|||..  .|   ||  .||. ..   . . . |.|. .  .|
ssedhenedkvfs----rteddiilyavfdGydGekaaefveqrLvaelllgdlseeaeaepkllll-qvieeverkf

Phosphatase PP2D1.AA Subfamily.PPM1E.PD 594-621 59 6.2e-06 15.6 In-house 242-269 (269) Show / Hide
Range on Protein: 594-621
Range on HMM: 242-269/269
Sequence Identity: 59% (16 aa)

AEYVSHELVNAALLAGSRDNITVMVIFL
. |...||.||  |||.|||||.|.|| 
lsevakllveaakeagssDnitvvvvfl

Phosphatase PP2D1.AA Subfamily.PPM1H.PD 415-478 31 7.5e-06 14.9 In-house 284-357 (402) Show / Hide
Range on Protein: 415-478
Range on HMM: 284-357/402
Sequence Identity: 31% (23 aa)

KTTRGLGFH------GNLKLKKSIIPAPQTISVPIDDLC----QFLIVATNGLWEVLDKEEVTALAMTTFHMYK
.||||| |       ||..|  . |.|.   . ....     . ||.||.|||.||. |||...   ... .. 
gvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvd

Phosphatase PP2D1.AA Subfamily.PPM1H.PD 354-396 32 8.5e-06 14.7 In-house 174-214 (402) Show / Hide
Range on Protein: 354-396
Range on HMM: 174-214/402
Sequence Identity: 32% (14 aa)

ISGILHVANTGNVQAVLCRNGKGFCLTKEHTTRntNERRRILQ
. | |.||| |. .|.|.|...   | ...|     ||.|...
llgklYvanaGDsRailvrkdeiiplsadftPe--teRqRlqe

Sequence
Name Sequence Type Origin Length Description Download
PP2D1.AA Protein None 630 None Fasta, JSON
PP2D1.NA RNA None 1890 None Fasta, JSON
PP2D1.AA.PD_162-619 Protein Phosphatase Domain None 458 None Fasta, JSON