Gene PPM1B
PPM1B
Species: Human
Alias: PPM1B, PP2CBETA, PP2CB, PPC2BETAX, PP2C-beta-X, MGC21657
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPM1B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPM1B.AA | Family.PPM.PD | 11-366 | 38 | 3.3e-114 | 372.1 | In-house | 4-357 (495) | Show / Hide |
Range on Protein: 11-366
Range on HMM: 4-357/495
Sequence Identity: 38% (138 aa)
EKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLeDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGF
.... .. .|||||| .|||||| ||||||..| .. . |.|.|.|.|||.|...|.... .| .... .... . || . | | |.||. .|..|
aarteasssnglrygvasmqgwrsemeDahvvvenlenne-dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkaf
LKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI--QRVNGSLAVSRALGDYDYK
|..||.... . . ..||.||| |.|..|..|. |.|||||||.|||.. ..|||| ||.|.|||..|||.|.| .||||.|||||||||.|.|
leldeelseelneksagkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvirdgrvnGvlavsRalGdfdlk
CvdgkgpTEQL-VSPEPEVYEILRA-EEDEFIILACDGIWDVMSNEELCEYVKSRL-EVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEA
.||. ||.||.. . |||||..||.||.|||.||||..|.|...| | . |||.... .||..|.||||||.....|......|.....
k------eeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsrDNiTvlvvalyenikqqnrf
VKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAV
|.....|............... || .|.......... .. ... . . .|..|..
vlnknslmtrrstfedttlrrlqeeispptgnlamvftdiksstflwelfpnamrtaikth
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| Phosphatase | PPM1B.AA | Subfamily.PPM1A.PD | 13-326 | 66 | 1.5e-157 | 513.7 | In-house | 1-309 (309) | Show / Hide |
Range on Protein: 13-326 Range on HMM: 1-309/309 Sequence Identity: 66% (210 aa) HNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRaagksGSALELSVENVKNGIRTGFLK .|..|.|||||||||||||||||||||||||...|..|.|||||||.||||||.|..||..||||.|...|.|. .|. . |.|.||...|.|||. eneegegnglryglssmqgwRvemEDahtavidlpsklkdwsffavfDGHaGskvskycakhlleaileeeefk-----askeksskekvkealrkgfLe IDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDG .|| .|....|..|.|.||||||.|..|||..|..|||||||||.|||.|.|.|.||||..|.|||||.||||||||.||||||||||||||||||. . lDekirklvelskgedksGsTavvvlvspkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmikRvnGsLAvsRalGDydykekpe KGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSEL |..|||||||||||. | | |||||..||||||||||||||..|.|||||||.||||.|.|...||||.||||||||..||....|||||.||.||..|| kkateqlvspepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtddleevanelldtcLekgsrDNmsvilvllpgapkvseeaikkekel DKHLESRVEEIMEK ||.||..|||..|| dkeleekveevlek |
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| Phosphatase | PPM1B.AA | Group.PPM.PD | 12-370 | 40 | 3.3e-118 | 385.3 | In-house | 28-395 (459) | Show / Hide |
Range on Protein: 12-370 Range on HMM: 28-395/459 Sequence Identity: 40% (150 aa) KHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLedwSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSV------ENVKNG .. .| ||||||| .|||||| ||||.|..| . . |||.|.|||.|...|.... .| .... . . .. | . .| |. |.||. . lessagsgnglrygvasmqgwrkemEDrhvivenfdnnd---sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvkka IRTGFLKIDEYMRNFSDLRN-GMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI-QRVNGSLAVSRALG |..||..||.... .. . ..||.||| ..|..|..|. |.|||||||.|||.. ..|||| ||.|.|||..|||||.| .||||.||||||||| lrsafleldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidgRvnGilavsRalG DYDYKCvdgkgpTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEV-----SDDLENVCNWVVDTCLHKGSR------DNMSIVL .|.| .||.||.||.| . |||||..||.||.|||.||||..|.|...|| . |||.... .||..|.|||.||.....|....|. dhdlkk------eeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgstgdgtscDNiTviv VCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPpGGGLAGKRNVIEAVYSRL ....|.|||...|...|...|.|..||||.. . .... .. ..||. . . ..||. .....|..| .| vtlndamrrqleivkkeevleeelafmvaelteksgltallsvqlklldaqaeeeitsv-qdglqvtdrngeiiyqgl |
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| Phosphatase | PPM1B.AA | PP2Cc | 13-293 | 29 | 1.2e-99 | 338.24 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 13-293 Range on HMM: 1-338/338 Sequence Identity: 29% (110 aa) HNAHGAGNGLRYGL--SSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAG----------------KSGSA |. .| ..|.|||. |||||||..||||| ... ||.|.|||.|...|.||. ||.||. ...| . . HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP----------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWR-MW- LELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQ----------VCFSTQDHKPCNPREKERIQNAG . . |.... .| .||..|| . .||| . |.....|. |.|||||||.|||. . . |.|||| |..|..||..|| HDKWFEDWEDALRKAFLRMDEEI--------------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAG G--------SVMIQ-----RVNGS---LAVSRALGDYDYKCVD----------------GKGPTEQLVSPEPEVYEILR------AEEDEFIILACDGIW | || . ||||. ||||||.||..||. . ....|..|..||.|... . ..|.|.||.|||.| GRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKW-KEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLW DVMSNEELCEYVKSRL-----------------------EVSDDLENVCNWVVDTCLHKGSRDNMSIVLV |||||.|....|...| .. |.. ... ..| .. .|||....| DVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----CDNMTVIVV |
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| Phosphatase | PPM1B.AA | PP2C | 22-288 | 39 | 4e-99 | 340.4 | Pfam | 1-284 (284) | Show / Hide |
Range on Protein: 22-288 Range on HMM: 1-284/284 Sequence Identity: 39% (116 aa) LRYGLSSMQGWRVEMEDAHTAVVGIP---HGLEDWSFFAVYDGHAGSRVANYCSTHLL----EHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKID ..||...||||| .|||||.. | ..|.||||.|||.|...|.||. || ... ...|. . ..|....| .||..| WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNP---------KDVEQALRKSFLECD EYMRNFS---DLRN----GMDRSGSTAVGVMISPKH--IYFINCGDSRAVLYRNGQVC----FSTQDHKPCNPREKERIQNAGGSVM---IQRVNGS-LA . | | . | ..||.||| ..|.... .|. ||||||||| |||.. . |.|||| |..|..||..|||.|| .||||. || TDMMFYSAPWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLA VSRALGDYDYKCVDGKGPTEQLVSPEPEVY-EILRAEE-DEFIILACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNM ||||.||..||. ....|.||.|..||.. |. . .. |||.||||||.|||||..|.|. |..... .|.. .|. .||.|. .||.||. VSRAFGDFHYKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIAYGSEDNI |
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| Phosphatase | PPM1B.AA | Subfamily.PPM1G2.PD | 17-293 | 38 | 4.9e-82 | 265.3 | In-house | 5-275 (275) | Show / Hide |
Range on Protein: 17-293 Range on HMM: 5-275/275 Sequence Identity: 38% (109 aa) GAGNGLRYGLSSMQGWRVEMEDAHTA---VVGIPHGlEDWSFFAVYDGHAGSRVANYCSTHLLEHITTnedfraagksgsALELSVENVKNGIRTGFLKI || . .. |.|||||.|..|||||. .. . .. ..|||.||| |..||.|....| . |.. ... ..... .. .||.. ganariavgvssmqGyrlnmeDahilenelleksdd-kslalfavfDGhGGakvakyagkklikkiak------------kksfkegaleqilkdaflet DEYMRNFSDLRNgmDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGK || ... . |.. . .||||| |.|. ...| |.||||||| .|.| . |||| . ||.||..||| | ..||||.||.||||||. .| . | Deellkdeklkd--esaGstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvelnrvngnLalsralgDfefkknvkk GPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSR------DNMSIVLV .| ||.| .|.| . |.|||..|||||||||..|.|....|..|| .|..... ..|.|| .|. |||..|.| kpeeqivtavPDvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapdssntgvGcDnmtvviv |
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| Phosphatase | PPM1B.AA | Subfamily.PPM1E.PD | 27-294 | 33 | 7.9e-56 | 179.3 | In-house | 16-268 (269) | Show / Hide |
Range on Protein: 27-294 Range on HMM: 16-268/269 Sequence Identity: 33% (92 aa) SSMQGWRVEMEDAHTAVVGIPHGLE-----DWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKsgsalelsvenvkNGIRTGFLKIDEYMRNFS .... | ||| | |. . . .| . .||||.|||.|. |.| ..|| |.. .|.. . . .. .| ..|| . . . aavknkrrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa-------------ealkeafkltDerflqka DlRNGMdRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI---QRVNGSLAVSRALGDYDYKcvdgkgpteQ |... .|||||| |.|. ...| |||.|.| |.|.. .. ||| ...||.||..||| |. ||||.|.||||.||...| . e-rekl-ksGstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk---------p LVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSD-DLENVCNWVVDTCLHKGSRDNMSIVLVC || |..| |. ......||||||.|||. .||... |.. |. . ||..| . .|.. ..||.||...|.| yvsgeadvaeveldgsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvvvf |
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| Phosphatase | PPM1B.AA | PP2C_C | 289-369 | 64 | 2e-55 | 185.13 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 289-369 Range on HMM: 1-82/82 Sequence Identity: 64% (53 aa) SIVLVCFSNAPKVSDEAVKKDSELDKHLESRVEEIMEK-SGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSR ||...|| .|||||.|||||. ||||.||.|||||.|| ..|...|||.|||. |..|.||||||||||. ||..|||||.. SIIIICFPGAPKVSEEAVKKEAELDKYLEQRVEEIIEKMHSEHEYPDLLHVMKCLASEDIPNLPPGGGLHSKRSCIEAVYNQ |
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| Phosphatase | PPM1B.AA | Subfamily.PPM1G.PD | 126-294 | 42 | 5.5e-49 | 157.7 | In-house | 304-481 (482) | Show / Hide |
Range on Protein: 126-294 Range on HMM: 304-481/482 Sequence Identity: 42% (76 aa) GMDrSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVM-IQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEP | | ||.||| .. |... | ||||.|| |||. |||| .. |.|||..||| | |||| | .||||||. || ..||..| |. Gkd-sGttavvaLvkgkklivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeLpaeeqmisalP EVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVS---DDLENVCNWVVDTCLHKGS------RDNMSIVLVC . . . |||||..|||||||.||| .| ..|...|. | | ..|. ..|.|| . |||..|.| DikklilteedeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLlDaCLapdtsgDGtGCDnmtvvivq |
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| Phosphatase | PPM1B.AA | Subfamily.LRR-PP2C.PD | 20-293 | 34 | 1.2e-46 | 149.2 | In-house | 8-255 (257) | Show / Hide |
Range on Protein: 20-293 Range on HMM: 8-255/257 Sequence Identity: 34% (87 aa) NGLRYGLSSMQGWRVEMEDAHTaVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAgKSGSALELSVENVKNGIrtgflkideymrn . .. | | | | | ||| . . | .. .| ..|..|||.|.. |...| .| .. | | . .|. . .... |. |.||. |.| srfkvgfsdmiGrrptmedelv-iyGsfrdksdedyyalfdGhgGraaakfaseelykilaelldlnna-nPlkslkkaykeistqi------------- fsdlR--NgmDRSGSTAVGVMISPKHIYFINCGDSRAVLY-RNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ----RVNGSLAVSRALGDYdYkcvdg ...| | ||||.|| ..| . |||| ...|..||...|| |. .|||| ||||||||| . | | |.|.. .. ..|.|.| ----serp--kfiGttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGds-f----- kgpTEQLVSPEPEVY-EILRAEEDEFIILACDGIWDVMSNEELCEYVKSrlevSDDLENVCNWVVDTCLHKGSRDNMSIVLV ||||||||..|.|| .| | . . | |. .. .| ..|| ||.|.... ---lePfvvpdPdlsqsleiskkdkflilacdGiwdlisdeeaveivag----isdpekaaeklrdlayssGstdnisvivi |
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| Phosphatase | PPM1B.AA | Subfamily.ILKAP.PD | 25-293 | 31 | 2.2e-46 | 148.6 | In-house | 12-298 (298) | Show / Hide |
Range on Protein: 25-293 Range on HMM: 12-298/298 Sequence Identity: 31% (89 aa) GLSSMQGWRVEMEDAHTAVVGIP-------HGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNedFRAagKSGSALElsvENVKNGIRTGFLKIDEYM . .. .| | ||||||. . . . . |..||.||||||| .... ..| ..| .. . .. || . ...| ..| | || . . afaerkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkvivek--lpk--edvsakd---keikkclvdafkktDeef RNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNG---Q--------VCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYD .. . . ..||||| |.. .| | |||.|||.|. . . ..||.| . |..|||.|||.|.||.|.|.|||..|| .| . lklaskakPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGvlevsRsiGDgr YKCVDgkgpteqlVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDD---------------LENVCNWVVDTCLHKGSRDNMSIV . |. .|.| . |.| |..|||||.|.|....| ... . || ||.| .|. . ...|| ||....|| fkelg--------vistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlededdrkikqeegksaeevrfevacerlAseavkrgssDnvtvl LV lv |
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| Phosphatase | PPM1B.AA | Subfamily.PPM1L.PD | 28-295 | 32 | 1.1e-41 | 133.2 | In-house | 18-273 (273) | Show / Hide |
Range on Protein: 28-295 Range on HMM: 18-273/273 Sequence Identity: 32% (88 aa) SMQGWRVEMEDAHTAVVGIPHGLEdWSFFAVYDGHAGSRVANYCSTHLLEHITTNE-DFrAAGKSGSaLELsveNVKNGIRTGFLKIDEYMrnFSDLRNG |..| | .||| . .| .. . |||||.||| | |... | . | .. .. .| | . . . | .. . | .|| .... .| .| svlGrrprmedrfeieediknktg-esffavfdGhGGefaaefakdvlvkaiknkliel-dadkent-vpi---nfsklltdeilsvdekl--lekakra MDRSGSTAVGVMISPKHIYFINCGDSRAVLY-RNGQVCFSTQDHKPCNPREKERIQNAGGSVMI---QRVNGSLAVSRALGDYDYKcvdgkgpTEQLVSP .||. ... ... | |||| ||| ..|. . |||| ...|. ||..||| . . ||.| ||.||||||| | ..|| ..|.. ediaGttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk-------dknlvia EPEVYEI-LRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDdleNVCNWVVDTCLHKGSRDNMSIVLVCF . | . ||.|||.||.|| .|||| ....| ||. | .| . ..|| ||.....|. dpdiltfdlddhkpeflilasdGlwdtfsneeavrfikerlkepd---fGakslvlesfkrGsvdnitvlvvkl |
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| Phosphatase | PPM1B.AA | Subfamily.PPM1D.PD | 26-291 | 30 | 7.4e-40 | 127.2 | In-house | 12-309 (311) | Show / Hide |
Range on Protein: 26-291 Range on HMM: 12-309/311 Sequence Identity: 30% (93 aa) LSSMQGWRVEMEDAHTAVVGIPH-G-LEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFraagksgsaLELSVENVKNGIRTGFLKIDEYMRNF--- .. || | ||| . |. . . ....|.||.||| | |.. . ||.. |. ...| | . |.| . || .||..| |.. . seadqGgrkymeDvvaivlereesaeeaeaafvavfDGHGGkeAakfarehlwsvikkqkkf---------lssepedvleAireaflatheamkkklae -SDLRNGM-DRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQ------VCFSTQDHKPCNPREKERIQNAGGSVMIQ----RV---------NGS---- ..| .|.|| |.| ...| . |||..|| . . |.|||| .|.|||||...||.|...|| || || WpktksgllstaGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaaksGvkRvvWkRprlehngptvid ----LAVSRALGD-YDYKCVDGkgptEQLVSPEPEVYEILR-AEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSDD----LENVCNWVVDTCLHKGSR |.|.||| . |. | | .|||||.|.. . .|..||||| ||.|.|.. |. . |..|.. ..| . .|.. |.. .. ||. eiPFLavaRslGDlWsynaksg----eyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealqrwrs -----DNMSIV |.. kklraDnvsvi |
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| Phosphatase | PPM1B.AA | Subfamily.PPM1K.PD | 24-294 | 30 | 1.6e-38 | 122.5 | In-house | 12-263 (264) | Show / Hide |
Range on Protein: 24-294 Range on HMM: 12-263/264 Sequence Identity: 30% (82 aa) YGLSSMQGWRVEMEDAHTavvgIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDfrAAGKSGSALELSVENVKNgirtgflkideYMRNFSDL | |..| | | || . . . .| .|||.|||.|| |... ..| |.. . . | . |.. ..... .. . . ||.| vGkdsliGkraenedrfk----lkeldpdllyfavfdGhgGssaadfvhdkleeivrrlle--kekdleevlkqafeeldk-----------klkrylef R---NGMDRSGSTAVGVM-ISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI-----QRVNGSLAVSRALGDYDYKCVdGkg | .. ... . |||||.| |||. |.||.| . |||||..||||| .||. ||..|.||| | | | . || svaeaellssGttatvsllrdGnelvlaslGdsrailcrnGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkry-G-- pteQLVSPEPEVYEIlRAEEDEFIILACDGIWDVMSNEELCEYVKsrleVSDDLENVCNWVVDTCLHKGSRDNMSIVLVC .. . ..| |..| ||| .|....|||..|. . | |. . |... | || ||..|.| ---viatPetkslkv-khaadsflvlitdgisfvvnsqelcdlvr----lchdpeeaahavteqalqygsednatavvvp |
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| Phosphatase | PPM1B.AA | Subfamily.PPM1G.PD | 17-96 | 43 | 1.4e-23 | 73.9 | In-house | 5-80 (482) | Show / Hide |
Range on Protein: 17-96 Range on HMM: 5-80/482 Sequence Identity: 43% (35 aa) GAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPhglEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAaGKSGSALE .. . | || |.||||||.|||||.... . ||.|.||||||| |. ||.||...| . .. .. ... |. .||| esneelsygasamqGWRvsmeDahncildld---edtslfavyDGhGGkevakycakklPdllkeskayke-gdvekale |
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| Phosphatase | PPM1B.AA | Subfamily.PDP.PD | 100-269 | 26 | 1.7e-20 | 63.8 | In-house | 125-333 (409) | Show / Hide |
Range on Protein: 100-269 Range on HMM: 125-333/409 Sequence Identity: 26% (55 aa) ENVKNGIRTGFLKIDEYMR--NF-----SDLRNG---MDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVC-----FSTQDHKPCNPREKERIQNAG ..|.. ....||..|. .. . ..|.. . ||..|. ..|...... | ||.|||| .. . ..|. |..||||... lkveealkkaFlrlDkdislealkkleekvleeavlkvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeH ---GS---VMIQRVNGSLAVSRALGDYDYKC---VDGKG----PTEQLVSP-----------EPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKS | .. .|. |.|| .|| ||. || .. | . .. | | |||| . .|.| |..|| ||.||..|||| ..|. PgeesktvirngRlLgeLaPlRAFGdvryKwskelqkkvlekllevkvvepkdyktPPYltaePevtshklrendkFLvlatDGLwdllsneevvslVge RLEVSDDLE |. ... . hlakkknka |
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| Phosphatase | PPM1B.AA | Subfamily.PPM1H.PD | 190-266 | 39 | 2.1e-13 | 40.0 | In-house | 277-357 (402) | Show / Hide |
Range on Protein: 190-266 Range on HMM: 277-357/402 Sequence Identity: 39% (32 aa) QRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVY--EI--LRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSD .|. . ..|.| |||.. | || . ..||.||| .. . .||. .||| ||.|||.|||| | |.. |. | aRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvd |
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| Phosphatase | PPM1B.AA | Subfamily.PHLPP.PD | 147-260 | 29 | 6.2e-13 | 38.6 | In-house | 122-228 (257) | Show / Hide |
Range on Protein: 147-260 Range on HMM: 122-228/257 Sequence Identity: 29% (34 aa) INCGDSRAVLYRNGQ-VCFSTQDHKPCNPREKERIQNAGGSVMI-QRVNGSLAVSRALGDYDykcvdgkgpTEQLVSPEPEVYEILRAEEDEFIILACDG | |. ..|| |||. . .| ... | .||..| . . ..||| .. .| || . . | |.|.| ..| .|.||..|| ... anvgkcklvlirnGkplplskvyileiddeelkrikeakaiitednkvnGviestrilGytf---------lfPvvlPkphvrsvlLteqdEllilGnka IWDVMSNEELCEYVKS |.|.| .|. | |. lWevlsideaveavrn |
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| Phosphatase | PPM1B.AA | Subfamily.TAB1.PD | 116-277 | 24 | 1.1e-12 | 37.6 | In-house | 124-305 (336) | Show / Hide |
Range on Protein: 116-277
Range on HMM: 124-305/336
Sequence Identity: 24% (45 aa)
YMRNFSDLRNGMdRSGSTAVGVMISPKHIYFINCGDSRAVLYRNG----QVCFSTQDHKPCNPREKERIQNAG---GSVMIQRVNGSLAVSRALGDYDYK
. ....| . . . |.||| ..| ...| .|.|||||.| .. .| .|| |. | .|... | . . ... || |..||| |
kinrlkelesei-sgGttavvalilnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykik
----CVDG-KGPTEQLVSPEPEVYEILRAEEDE-FIILACDGIWDVMS--------NEELCEYVKSRLEVSDDLENVCNWVVD
|| . ... . .|.. . .. | |..| ||. . . . .| | ...|.| .|..| . |||
kgykevdvlssAkgePiiatPdingpkdindlegfllLmSdGlykalieltnpptadvslallviqeaeksatlddvaqavvd
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| Phosphatase | PPM1B.AA | Subfamily.PPM1H.PD | 104-182 | 27 | 1.5e-09 | 27.3 | In-house | 140-214 (402) | Show / Hide |
Range on Protein: 104-182 Range on HMM: 140-214/402 Sequence Identity: 27% (21 aa) NGIRTGFLKIDEYMRNfsDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNprEKERIQN . . ||..|| ... . .. .. | ||. ... . .| | |||||.| |.... .|. | |..|.|. GalesaflemDeqiar--ereayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadftPet--eRqRlqe |
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