Gene PPM1N
PPM1N
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPM1N.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPM1N.AA | PP2Cc | 56-324 | 29 | 1.7e-79 | 271.3 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 56-324
Range on HMM: 1-338/338
Sequence Identity: 29% (107 aa)
HGGAEASGGLRFGA--SAAQGWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFGARHLPGHVLQELGPEPSEP--------------------
| .. .|.|.| |. |||| .|||||. . .|.| ||||| ..|.. ..||. |...|| . ...
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP----------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHD
---EGVREALRRAFLSADERLRSLWPRVETGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAG-----------AVAFSTEDHRPLRPRERERIHAAGG---
| . .|||.|||..||.. |||||.|... || |..|||||||.|.| |.. ||||.| ...||.|| .|||
KWFEDWEDALRKAFLRMDEEI-----------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQL-TEDHKPDNEDERRRIEQAGGRVM
-----TIRRR-----RVEGS---LAVSRALGDFTYK---------------EAPGRPPELQLVSAEPEVAALAR------QAEDEFMLLASDGVWDTVSG
... || |. ||||||.||. || | |.. ..|.|||.| . .|.|..|..||.|| .|
PMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLWDVMSN
AALAGLVASRLRLGLAPELL-----------------------CAQLLDTCLCKGSLDNMTCILV
. .| ..|| . . .|..|. |. ||||.|.|
QEVVDIVRKCLRKWHHK-PVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI---CDNMTVIVV
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| Phosphatase | PPM1N.AA | Subfamily.PPM1A.PD | 60-356 | 50 | 7.2e-120 | 389.9 | In-house | 5-308 (309) | Show / Hide |
Range on Protein: 60-356 Range on HMM: 5-308/309 Sequence Identity: 50% (154 aa) EASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFGARHLPGHVLQE----LGPEPSEPEGVREALRRAFLSADERLRsLW ... |||.| |..||||..|||||.....||. ..|..|||.|||.|.......|.|| ..|.| . | |. | |.||||..||..||..| . gegnglryglssmqgwRvemEDahtavidlpsklkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekir-kl PRVETG----GCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSRALGDFTYKEAPGRPPELQLV .....| |.||||.||||. ||||.||||||||||.|.|.|.||||.|..|.|.|||..|||.. ..||.|||||||||||..|||.| .... ||| velskgedksGsTavvvlvspkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmikRvnGsLAvsRalGDydykekpekkateqlv SAEPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRLGLAPELLCAQLLDTCLCKGSLDNMTCILVCFPGAPRPSEEAIRRELALDAALGCRI |.||||....|..||||..||.||.||..| . .| .|.|||... .| ....||||||.||| |||..|||..||||..|||||..| .||..| ... spepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtddleevanelldtcLekgsrDNmsvilvllpgapkvseeaikkekeldkeleekv AELCA .|... eevle |
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| Phosphatase | PPM1N.AA | Group.PPM.PD | 59-401 | 35 | 1.7e-94 | 307.1 | In-house | 32-396 (459) | Show / Hide |
Range on Protein: 59-401 Range on HMM: 32-396/459 Sequence Identity: 35% (131 aa) AEASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPpgwALFAVLDGHGGARAARFGARHLPGHVLQELGPEPSEP---------------EGVREALRRA |. |||.|... ||||. |||.|.. ... . ..|.| ||||||.||.| |..|| .....|. . .| | |..||| | agsgnglrygvasmqgwrkemEDrhvivenfdnnd---sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvkkalrsa FLSADERLRSLWPRVE----TGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRR-RRVEGSLAVSRALGDFTY || ||.|.. . | ..|.||||.|.... || |..|||||||.|.| . ..|| | .|.|||||..|||... ||.|.|||||||||. . fleldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidgRvnGilavsRalGdhdl KEapgrppELQLVSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRL-----GLAPELLCAQLLDTCLCKGSL------DNMTCILVCFP |. | |.|||||.| . . ||||. |||||.|| .| .. .|...| . ..| . .|.|..| ||| ||.|.|.|... kk------eeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgstgdgtscDNiTvivvtln GAPRPSEEAIRRELALDAALGCRIAELCASAQKPPSLNTVFRTLASEDIPDLPPGGGLDCKATVIAEVYSQICQ .|.| ..|....| .|...| ...|||. .... |......|..... ....... .......|...| damrrqleivkkeevleeelafmvaelteksgltallsvqlklldaqaeeeitsvqdglqvtdrngeiiyqgls |
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| Phosphatase | PPM1N.AA | Family.PPM.PD | 59-396 | 36 | 1.6e-91 | 297.3 | In-house | 9-356 (495) | Show / Hide |
Range on Protein: 59-396 Range on HMM: 9-356/495 Sequence Identity: 36% (130 aa) AEASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPpGWALFAVLDGHGGARAARFGARHLPGHVLQELGPEPSEP---------EGVREALRRAFLSADE |. | |||.|... ||||. |||||. .| . . ..||.| ||||||.||.| |..|. .....| . .|. | |.||||.|||. || asssnglrygvasmqgwrsemeDahvvvenlenne-dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkaflelde RLRSLWPRVE---TGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRR--RRVEGSLAVSRALGDFTYKEapgr .|.. ... ..|.||||.|.... || |..|||||||.|.| . ..|| | .|.|||||..|||... ||.|.||||||||||.|. elseelneksagkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvirdgrvnGvlavsRalGdfdlkk---- ppELQL-VSAEPEVAALARQ-AEDEFMLLASDGVWDTVSGAALAGLVASRL-RLGLAPELLCAQLLDTCLCKGSLDNMTCILVCFPGAPRPSEEAIRREL | |. |||||.. . . ||||. |||||.|| .| .. || ..| . . ..| ....|.|..| ||| ||.|...|....... ........ . --eeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsrDNiTvlvvalyenikqqnrfvlnkn ALDAALGCRIAELCASAQKPPSLNTVFRTLASEDIPDLPPGGGLDCKATVIAEVY |.. . ... . . ..|. | .|. . . .|| . . ..| ..|. .|. . slmtrrstfedttlrrlqeeispptgnlamvftdiksstflwelfpnamrtaikt |
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| Phosphatase | PPM1N.AA | PP2C | 65-319 | 35 | 3.5e-75 | 260.87 | Pfam | 1-284 (284) | Show / Hide |
Range on Protein: 65-319
Range on HMM: 1-284/284
Sequence Identity: 35% (101 aa)
LRFGASAAQGWRARMEDAHCTWLSLP---GLPPGWALFAVLDGHGGARAARFGARHLP----GHVLQELGPEPSEPEGVREALRRAFLS--ADERLRS--
...|... |||| |||||. .. . . |..||| |||||..||.. . ||. .. ....|. | .|||..||. .|. ..|
WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYSAP
-LWPR-----VETGGCTAVVLLVSPRF--LYLAHCGDSRAVLSRAGAVA----FSTEDHRPLRPRERERIHAAGGTIR---RRRVEGS-LAVSRALGDFT
. ...|||||. .... || |.||||||||.|.| .. . |.||.| ...||.|| .|||.. || |. ||||||.|||
WHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGDFH
YKEAPGRPPELQLVSAEPEVA-ALARQAE-DEFMLLASDGVWDTVSGAALAGLVASRLRLGLAPELLCAQLLDTCLCKGSLDNM
|| .. .|. |.|.|||.. .. . |||..||.||.|| .| . ..| ... . |...| .|.|.|. .|| ||.
YKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIAYGSEDNI
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| Phosphatase | PPM1N.AA | Subfamily.PPM1G2.PD | 65-324 | 39 | 3.5e-69 | 223.1 | In-house | 10-275 (275) | Show / Hide |
Range on Protein: 65-324 Range on HMM: 10-275/275 Sequence Identity: 39% (106 aa) LRFGASAAQGWRARMEDAHCT---WLSLPGlPPGWALFAVLDGHGGARAARFGARHLPGHVLQelgPEPSEPEGVREALRRAFLSADERLRSL-WPRVET ...|.|. ||.| ||||| . |... . |||||.||||||..|......| . . . . . ....|. |||. || |.. . |. iavgvssmqGyrlnmeDahilenelleksd-dkslalfavfDGhGGakvakyagkklikkiak---kksfkegaleqilkdafletDeellkdeklkdes GGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAAL |.|||| |.. . || | .|||||||| .| | . ||.| . |..|| ||||.. || |.||.|||||||..|..|| |.| |.|.| .. aGstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfvelnrvngnLalsralgDfefkknvkkkpeeqivtavPDvlvk ARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRLGLAPELLCAQLLDTCLCKGSL------DNMTCILV .|||..|| ||.|| .. . . || .||. | ... .. .|||.|| . | ||||...| kldeddeflvLaCDGiWDvltnkevvdlvrerlvsgakldeiieelldkclapdssntgvGcDnmtvviv |
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| Phosphatase | PPM1N.AA | PP2C_C | 320-398 | 48 | 2.7e-49 | 164.93 | Pfam | 1-82 (82) | Show / Hide |
Range on Protein: 320-398 Range on HMM: 1-82/82 Sequence Identity: 48% (40 aa) TCILVCFPGAPRPSEEAIRRELALDAALGCRIAELC---ASAQKPPSLNTVFRTLASEDIPDLPPGGGLDCKATVIAEVYSQ ..|..||||||..||||...| .||..| .|..|.. .|....|.|..|...|||||||.|||||||..|...|..||.| SIIIICFPGAPKVSEEAVKKEAELDKYLEQRVEEIIEKMHSEHEYPDLLHVMKCLASEDIPNLPPGGGLHSKRSCIEAVYNQ |
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| Phosphatase | PPM1N.AA | Subfamily.PPM1E.PD | 69-325 | 36 | 3.4e-47 | 151.0 | In-house | 15-268 (269) | Show / Hide |
Range on Protein: 69-325 Range on HMM: 15-268/269 Sequence Identity: 36% (90 aa) ASAAQGWRARMEDAHCTWLSLPGL-----PPGWALFAVLDGHGGARAARFGARHLPGHVLQELGpEPSEPEgvrEALRRAFLSADERLRSL-WPRVETGG . | .. | .||| | . .| | . | |||.||||| ||.. |.||. .. .. ...|. |||..|| .|||. ...|.|||| | iaavknkrrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqek-lkedpa---ealkeafkltDerflqkaereklksG CTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIR---RRRVEGSLAVSRALGDFTYKeapgrppelQLVSAEPEVAA .. . ||.| |||.|.| | | . .. |.| |..|..|| .|||.. || |.|.||||.|| ..|. ||.|..|| .. . ......||.|| stavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklk---------pyvsgeadvae LARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRLGL-APELLCAQLLDTCLCKGSLDNMTCILVC .||.| . || . |. | . . .|... .|| ||.| ..| veldgsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvvvf |
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| Phosphatase | PPM1N.AA | Subfamily.PPM1G.PD | 161-326 | 40 | 9.4e-44 | 140.5 | In-house | 307-482 (482) | Show / Hide |
Range on Protein: 161-326 Range on HMM: 307-482/482 Sequence Identity: 40% (72 aa) GGCTAVVLLVSPRFLYLAHCGDSRAVLSRAG-AVAFSTeDHRPLRPRERERIHAAGGTIR-RRRVEGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVA |.|||| || . |. | ||||.||||.| |. .| ||.| . |.|||..||| . || | | .|||||| .||. |.| |..|| |.. sGttavvaLvkgkklivanaGDsRcvlsrnGkaldlsi-DhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeLpaeeqmisalPDik ALARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRLG---LAPELLCAQLLDTCLCKG------SLDNMTCILVCF |. . ||||. ||.||.|...| | ..|. . .| .|||.|| . ||||...| . klilteedeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLlDaCLapdtsgDGtGCDnmtvvivql |
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| Phosphatase | PPM1N.AA | Subfamily.LRR-PP2C.PD | 66-324 | 31 | 3.5e-41 | 131.4 | In-house | 11-255 (257) | Show / Hide |
Range on Protein: 66-324 Range on HMM: 11-255/257 Sequence Identity: 31% (82 aa) RFGASAAQGWRARMEDAHCTWLSLPGLpPGWALFAVLDGHGGARAARFGARHLPGHVLQELGPEPSEPEgvrEALRRAFLSADERLrSLWPrvETGGCTA . | | | |. ||| . | . .. ..|..||||| .||.| . .|. . . | ....|. ..|..|. . . .. |.| |.||. kvgfsdmiGrrptmedelviyGsfrdk-sdedyyalfdGhgGraaakfaseelykilaelldlnnanPl---kslkkaykeistqi-serp--kfiGtta VVLLVSPRFLYLAHCGDSRAVLS-RAGAVAFSTEDHRPLRPRERERIHAAGGTIRRR----RVEGSLAVSRALGDFTYKeapgrPpelqLVSAEPEVA-A ..|. . |.| ||||.||. . | . ||.| ..|..||...|||. ||.| |||||||||. | | ..|.. .| . asvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsfle-----P----fvvpdPdlsqs LARQAEDEFMLLASDGVWDTVSGAALAGLVASRLrlglAPELLCAQLLDTCLCKGSLDNMTCILV .|.|..|| ||.|| .| .||. || . .| | .|| ||.. |.. leiskkdkflilacdGiwdlisdeeaveivagis----dpekaaeklrdlayssGstdnisvivi |
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| Phosphatase | PPM1N.AA | Subfamily.ILKAP.PD | 71-286 | 33 | 1.2e-35 | 113.4 | In-house | 15-245 (298) | Show / Hide |
Range on Protein: 71-286 Range on HMM: 15-245/298 Sequence Identity: 33% (78 aa) AAQGWRARMEDAHCTWLSLPGL---PP----GWALFAVLDGHGGARAARFGARHLPGHVLQELGPEPSEP--EGVREALRRAFLSADERLRSLWPR---V .| |. ||||| | . . .|| |||.| ||..| |..| .....| | . .. .|. || ..|| ..| . | erkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflklaskakPv ETGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAF-----------STEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSRALGDFTYKEAPgrppe |.||||.|| || | |||.||| || . ..|| | ||.||. |||..| || |.|.|||..|| .||. WkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdgRvlGvlevsRsiGDgrfkelg----- lqlVSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALA |...|.| . ...| |..|| ||.|.... . . ---vistPdvkkceLtenDlfvvlaCDGLwkvfeadevv |
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| Phosphatase | PPM1N.AA | Subfamily.PPM1L.PD | 71-326 | 35 | 4.8e-35 | 111.4 | In-house | 18-273 (273) | Show / Hide |
Range on Protein: 71-326 Range on HMM: 18-273/273 Sequence Identity: 35% (91 aa) AAQGWRARMEDAHCTWLSLPGlPPGWALFAVLDGHGGARAARFGARHLPGHVLQEL-----GPEPSEPEGVREALRRAFLSADERLR-SLWPRVETGGCT . .| | |||| . | .||| ||||| || | |. ....| | ..| . | ||.||.| ... |.||.. svlGrrprmedrfeieedikn-ktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekakraediaGtt AVVLLVSPRFLYLAHCGDSRAVLSRA-GAVAFSTEDHRPLRPRERERIHAAGGTIRRR---RVEGSLAVSRALGDFTYKEapgrppeLQLVSAEPEVAAL ||. . | .| |||| || | . ||.| ...|| ||. ||| | | ||.| ||.||||||. |..|| |.|.. .. . . ||..| alialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkd-------knlviadpdiltf AR-QAEDEFMLLASDGVWDTVSGAALAGLVASRLRlglAPELLCAQLLDTCLCKGSLDNMTCILVCF ||||.||| | . || |.. | . .||.||.| ..| . dlddhkpeflilasdGlwdtfsneeavrfikerlk---epdfGakslvlesfkrGsvdnitvlvvkl |
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| Phosphatase | PPM1N.AA | Subfamily.PPM1D.PD | 65-289 | 34 | 2.8e-34 | 108.9 | In-house | 8-267 (311) | Show / Hide |
Range on Protein: 65-289 Range on HMM: 8-267/311 Sequence Identity: 34% (88 aa) LRFGASAAQGWRARMEDAHCTWLSL--PGLPPGWALFAVLDGHGGARAARFGARHLPGHVLQELGPEPSEPEGVREALRRAFLSADERL---RSLWPRVE || ..| || | ||| . |. . ..| .|| ||||| ||.| .|| . . .. . |||| |.||.|.|||. | ... ||. . lrvtseadqGgrkymeDvvaivlereesaeeaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpktk -----TGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGA------VAFSTEDHRPLRPRERERIHAAGGTIRRR----RV---------EGS--------L | | || |... . ||.|| |||..||. |.||.| |.|.|||. .|| . . ||.| |||.|.|||. | sgllstaGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaaksGvkRvvWkRprlehngptvideiPFL AVSRALGDF-TYKEAPGRppelQLVSAEPEVAALARQAEDE-FMLLASDGVWDTVSGAALAGLV ... |. .|| ||.| .. ..| |..|||||.|. ..... .| avaRslGDlWsynaksge----yvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvv |
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| Phosphatase | PPM1N.AA | Subfamily.PPM1K.PD | 67-325 | 36 | 9.8e-32 | 100.3 | In-house | 12-263 (264) | Show / Hide |
Range on Protein: 67-325 Range on HMM: 12-263/264 Sequence Identity: 36% (95 aa) FGASAAQGWRARMEDAHCtwlsLPGLPPGWALFAVLDGHGGARAARFGARHLPGHVLQELgpePSEpEGVREALRRAFLSADERLRSLWPR------VET | . .| || || . | | | ||| |||||. || | .| .| . | . | . ..| | .||. |..|.... | || |.|| vGkdsliGkraenedrfk----lkeldpdllyfavfdGhgGssaadfvhdkleeivrrll---eke-kdleevlkqafeeldkklkrylefsvaeaells GGCTA-VVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIR-----RRRVEGSLAVSRALGDFTYKEApGrppelqlVSAE | || |||||.| | | |.|| | | |.|||.||||.. . .|.. ||..|.|||.. |. | | |.|| | |. sGttatvsllrdGnelvlaslGdsrailcrnGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkry-G-------viat PEVAALAR-QAEDEFMLLASDGVWDTVSGAALAGLVasrlRLGLAPELLCAQLLDTCLCKGSLDNMTCILVC | |..| .||. . |. |. || || || . .. | || || |...| Petkslkvkhaadsflvlitdgisfvvnsqelcdlv----rlchdpeeaahavteqalqygsednatavvvp |
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| Phosphatase | PPM1N.AA | Subfamily.PPM1G.PD | 63-152 | 43 | 1.6e-18 | 57.3 | In-house | 8-91 (482) | Show / Hide |
Range on Protein: 63-152 Range on HMM: 8-91/482 Sequence Identity: 43% (38 aa) GGLRFGASAAQGWRARMEDAHCtwlSLPGLPPGWALFAVLDGHGGARAARFGARHLPgHVLQELgpEPSEPEGVREALRRAFLSADERLR | .|||| |||| ||||| .. | ..|||| |||||. |.. |..|| ..|.| . . . |..||. |||. |. |. eelsygasamqGWRvsmeDahn---cildldedtslfavyDGhGGkevakycakklP-dllkes--kaykegdvekaleeaflkvDkkll |
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| Phosphatase | PPM1N.AA | Subfamily.PDP.PD | 151-291 | 28 | 1e-15 | 48.1 | In-house | 155-324 (409) | Show / Hide |
Range on Protein: 151-291
Range on HMM: 155-324/409
Sequence Identity: 28% (47 aa)
LRSLWPRVETGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVA-----FSTEDHRPLRPRERERIHAA---GG---TIRRRRVEGSLAVSRALGDFTYK
|... .| . | .|.. |.... |..| ||.|||| . . ..|. ..| |||... ||. |. |.|| .||||. ||
leeavlkvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLaPlRAFGdvryK
E---A-----------PGRPP-ELQ---LVSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVAS
. ..| ... ..||||| . .| |..||.|| ||..| . . ||
wskelqkkvlekllevkvvepkdyktPPYltaePevtshklrendkFLvlatDGLwdllsneevvslVge
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| Phosphatase | PPM1N.AA | Subfamily.PPM1H.PD | 136-208 | 40 | 6.8e-13 | 38.3 | In-house | 138-211 (402) | Show / Hide |
Range on Protein: 136-208 Range on HMM: 138-211/402 Sequence Identity: 40% (30 aa) VREALRRAFLSADERLRSLWPR-VETGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRER | || |||. || .. . .|||||.| || ||.| |||||.|.| ... .|. | |.| viGalesaflemDeqiarereayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadftPeteRqR |
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| Phosphatase | PPM1N.AA | Subfamily.TAB1.PD | 148-280 | 28 | 8.5e-13 | 38.0 | In-house | 125-269 (336) | Show / Hide |
Range on Protein: 148-280
Range on HMM: 125-269/336
Sequence Identity: 28% (42 aa)
DERLRSLWPRVEtGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAG----AVAFSTEDHRPLRPRERERIHAAG---GTIRRRRVEGSLAVSRALGDFTYKE
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inrlkeleseis-gGttavvalilnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdykikk
APGRPPELQLVS-----AEPEVAALARQAEDE-FMLLASDGVWDTV
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gykevdvlssAkgePiiatPdingpkdindlegfllLmSdGlykal
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| Phosphatase | PPM1N.AA | Subfamily.PPM1H.PD | 216-293 | 30 | 1.7e-08 | 23.8 | In-house | 272-353 (402) | Show / Hide |
Range on Protein: 216-293 Range on HMM: 272-353/402 Sequence Identity: 30% (25 aa) GTIRRRRVEGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAAL----ARQAEDEFMLLASDGVWDTVSGAALAGLVASRL |. .. |. . ..|.| ||| | . ..|..||| | . ||. ..||.||.|| .| . | .|.. | gegkkaRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevl |
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