Gene PPM1F
PPM1F
Species: Human
Alias: KIAA0015, PPM1F, hFEM-2, FEM-2, CAMKP, POPX2, CaMKPase
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPM1F.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPM1F.AA | PP2Cc | 144-411 | 27 | 6.2e-89 | 302.67 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 144-411
Range on HMM: 1-338/338
Sequence Identity: 27% (101 aa)
VPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTD-----------------
.. . .|. .. ...... . |..|||.|| | .|.||||||| ..|.|.. | | . |.... ..|
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP---------------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWW
----------PEGALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQ----------VVKLMEPHRPERQDEKARIEAL
.| |||.||.|.| . .| |.||| | .|.||..|||...| ..|. .. | | |.|...||..|||..
RMWHDKWFEDWEDALRKAFLRMDEEI------------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQA
GG--------FVSHMDC--WRVNGT---LAVSRAIGDVFQK------------------------PYVSGEADAASRAL------TGSEDYLLLACDGFF
|| .|. .| |||||. ||||||.||.. | |||. | | .. | | . | |.|.||| .
GGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLW
DVVPHQEVVGLVQSHLT----------------------RQQGSGLRVAEELVAAARERGSHDNITVMVV
||...|||| .|...|. .. .. ..|..|. .|. .||.||.||
DVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----CDNMTVIVV
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| Phosphatase | PPM1F.AA | Subfamily.PPM1E.PD | 145-413 | 59 | 8.49999999999e-129 | 418.6 | In-house | 2-269 (269) | Show / Hide |
Range on Protein: 145-413 Range on HMM: 2-269/269 Sequence Identity: 59% (160 aa) PLAARaSQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFLR ||... ||... |||.|..|.|||||||||.|...|.||.|.| .||.||||||||||.||.|||.|.|....||..|..||. ||.|||..||..||. Plevk-sqkeyevsiaavknkrrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpaealkeafkltDerflq KAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAA ||.||.|.||.|.|..||....|.||||||||..||..|..|.||.||.|||.|||.|||..||.| ....|||||.|.|||||||| .|||||||||.| kaereklksGstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklkpyvsgeadva SRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFL . .|.||||||.|||||..|||...||| ||...|...... .||..||.||.|.||.|||||.|||| eveldgsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvvvfl |
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| Phosphatase | PPM1F.AA | PP2C | 155-406 | 34 | 3.9e-101 | 347.09 | Pfam | 1-284 (284) | Show / Hide |
Range on Protein: 155-406 Range on HMM: 1-284/284 Sequence Identity: 34% (99 aa) WLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVH----TNAARQPELPTD----PEGALREAFRR--TDQMFLR | ........ |..|||.|...|..|. |. .....|||||||||..||.|.. |.| | .......|.. .| |||..|.. ||.|| . WDYGFCRMQGWRHFMEDAHHCYPNMNCS--SSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYS ---KAKR----ERLQSGTTGVCALIAGAT--LHVAWLGDSQVILVQQGQVV----KLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGT-LAVSRAIGD .... | ..||.| |||.| . . |.||..|||...| ..|... |.. |.|...||..||...||.|.....|||||. ||||||.|| APWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGD VFQKP---------YVSGEADAA-SRALTGS-EDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNI ...|| .|. | | .. .| . ...|.|||||..||...|||...|..... . . ....|.|| ....||.||| FHYKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWN-DPMEACEKLVDYCIAYGSEDNI |
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| Phosphatase | PPM1F.AA | Group.PPM.PD | 147-416 | 38 | 1.2e-73 | 238.4 | In-house | 30-324 (459) | Show / Hide |
Range on Protein: 147-416
Range on HMM: 30-324/459
Sequence Identity: 38% (105 aa)
AARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFglsdpvnrAYFAVFDGHGGVDAARYAAVHVHTNAARQPELP-------------------TDP
.|.... ..... .. |..||||||. .|.. ..|.||||||| ||..|| . . . ..| .....|||.|| ..|. . ..|....
ssagsgnglrygvasmqgwrkemEDrhvivenfdnnd--------sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekv
EGALREAFRRTDQMFLRKAKRER---LQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDcwRVNGTLAV
.|||| |.||| | .|.||..|||...|...|..|.| . | ||...|. |||..||.| . ||||.||||||.||. | || | | ..
kkalrsafleldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidg--RvnGilav
SRAIGDVFQKPY---VSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTR----QQGSGLRVAEELVAAARERGSH------DNITVMVV
|| ...| ||.|| .||. .||| .|...|. .. . .||.|| .|...|||||||.||.| |
sRalGdhdlkkeeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgstgdgtscDNiTvivv
FLRDP
tlnda
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| Phosphatase | PPM1F.AA | Family.PPM.PD | 150-415 | 36 | 1.3e-73 | 238.2 | In-house | 10-288 (495) | Show / Hide |
Range on Protein: 150-415 Range on HMM: 10-288/495 Sequence Identity: 36% (105 aa) ASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFglsdpvNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELP-------------TDPEGALREAFR .|.... ..... . |..|||.|| . .... . ..|.||||||| ||..|| . | . ..| | .. . |||.|| sssnglrygvasmqgwrsemeDahvvvenlenne------dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkafl RTDQMFLRKAKRER--LQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHmDCWRVNGTLAVSRAIGDVFQK ..|. . ....... .|||| |..|| | .|.||..|||...|...|..|.| . | ||...|. |||..||.|. .||||.||||||.||.. | eldeelseelneksagkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvi-rdgrvnGvlavsRalGdfdlk P----YVSGEADAASRALTGS-EDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRD . .|| | | | ||.. ...| ||.|| .||. .||| ||...| ... . ..||||| .| ..||.|||||.||.| . keeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsrDNiTvlvvalye |
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| Phosphatase | PPM1F.AA | Subfamily.PPM1A.PD | 154-415 | 31 | 3.2e-58 | 187.5 | In-house | 9-281 (309) | Show / Hide |
Range on Protein: 154-415 Range on HMM: 9-281/309 Sequence Identity: 31% (87 aa) QWLVSIHAIRNTRRKMEDRHVSLPSFNQlfglsDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQP--------ELPTDPEGALREAFRRTDQMFLRK . ... . .. |..||| |. .... . ..|||||||.| ....|.| |.... .. . .. . |||..|..|. ... glryglssmqgwRvemEDahtavidlps-----klkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekirkl AKRER--LQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMdcwRVNGTLAVSRAIGDVFQKPY------- . .. .||.| |..|. .| .| .||| .|...|.|| | |.| ...|| |||. ||.| ||||.||||||.|| . | velskgedksGsTavvvlvspkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmik---RvnGsLAvsRalGDydykekpekkate --VSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQgSGLRVAEELVAAARERGSHDNITVMVVFLR-D ||.|.. .. . . ....|.||||| .||. .||. .|.|.|.... .||.||. . |.||.||..|..|.| qlvspepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtd-dleevanelldtcLekgsrDNmsvilvllpga |
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| Phosphatase | PPM1F.AA | Subfamily.LRR-PP2C.PD | 155-411 | 33 | 1.5e-49 | 158.8 | In-house | 10-255 (257) | Show / Hide |
Range on Protein: 155-411 Range on HMM: 10-255/257 Sequence Identity: 33% (87 aa) WLVSIHAIRNTRRKMEDRHVSLPSFNqlfglsDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPEL-PTDPEGALREAFRRTDQMFlrkAKRErLQS . |. . | |||. | ||. | . |.|.|||||| .||..|. ... | .| ...|. .|..|.. .. .. ..| fkvgfsdmiGrrptmedelviyGsfr------dksdedyyalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqi---serp-kfi GTTGVCALIAGATLHVAWLGDSQVILV-QQGQVVKLMEPHRPERQDEKARIEALGGFVSHM-DCWRVNGTLAVSRAIGDVFQKPYVSGEADAA-SRALTG ||| . .|| . .| .|||.|.| ..| ..| |.| ..|. ||..|||.| |||||||||||.||.| .|.| . | | . GttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsflePfvvpdPdlsqsleisk SEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQqgsglRVAEELVAAARERGSHDNITVMVV .. .|.||||| .|.. .| | .| . . . ||.| | ..|| |||.|.|. kdkflilacdGiwdlisdeeaveivagisdpe-----kaaeklrdlayssGstdnisvivi |
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| Phosphatase | PPM1F.AA | Subfamily.PPM1G2.PD | 152-411 | 35 | 2.1e-49 | 158.3 | In-house | 7-275 (275) | Show / Hide |
Range on Protein: 152-411 Range on HMM: 7-275/275 Sequence Identity: 35% (96 aa) QRQWLVSIHAIRNTRRKMEDRHVSLPSfnqLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTD-PEGALREAFRRTDQMFLRKAKRER . . |.. ... | .||| |. . |. .|| . |.||||||||| ..|.||. ... |..... . | .|..|| .||..|.. | . nariavgvssmqGyrlnmeDahilene---lleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdeklkd LQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMdcwRVNGTLAVSRAIGDV-FQKPY--------VSGEA ..|.| | .|| | || |||. .| ..|.| .| |.|....|| ||.| ||||. ||||.||.|||.|||.| | . | esaGstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfveln---rvngnLalsralgDfefkknvkkkpeeqivtavP DAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQgSGLRVAEELVAAARERGSH------DNITVMVV . |. ....|.||||| .||. .||| ||...|.... . ...|||. . . |. ||.||..| DvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsga-kldeiieelldkclapdssntgvGcDnmtvviv |
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| Phosphatase | PPM1F.AA | Subfamily.ILKAP.PD | 154-411 | 31 | 8.2e-46 | 146.8 | In-house | 7-298 (298) | Show / Hide |
Range on Protein: 154-411 Range on HMM: 7-298/298 Sequence Identity: 31% (91 aa) QWLVSIHAIRN-TRRKMEDRHVSLPSFNQLFGLSDP--VNRAYFAVFDGHGGVDAARYAAVHVHTNAAR------QPELPTDPEGALREAFRRTDQMFLR | . .| |. |..||| || | ... ... . .|.||||||.| |...|| ..| . . . . .. . .|..||..||. ||..| yklegafaerkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflk KAKR--ERLQSGTTGVCALIAGATLHVAWLGDSQVILVQ---QGQ--------VVKLMEPHRPERQDEKARIEALGGFVSHMdcwRVNGTLAVSRAIGDV .. ..|.|.|..|. . .|.|| ||||. .|. .|. .| | . | | ..|. ||. ||.| .||.| |.|||.||| |.. laskakPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdg---RvlGvlevsRsiGDg -FQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQ--------QG-SGL----R-VAEELVAAARERGSHDNITVMVV |. . | || . ...||||| ..|. .||| ... | . .| | . ..| | . | .||| ||.||..| rfkelgvistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlededdrkikqeegksaeevrfevacerlAseavkrgssDnvtvllv |
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| Phosphatase | PPM1F.AA | Subfamily.PPM1L.PD | 153-412 | 32 | 2.4e-41 | 132.1 | In-house | 10-272 (273) | Show / Hide |
Range on Protein: 153-412 Range on HMM: 10-272/273 Sequence Identity: 32% (87 aa) RQWLVSIHAIRNTRRKMEDRhvslpsFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV------HT---NAARQPELPTDPEGALREAFRRTDQMFL .. |...... | .|||| |. .... .. .||||||||| || .| . . .|... ..| . . | .|. .| |||| kkqnvavysvlGrrprmedr------feieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekll RKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILV-QQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVF--QKPYVSGE . .||| . ||... | || .|||. .|. ..|. . | |.|.. |. ||. |||.. .|||.| ||.|||.|| .| | . | . ekakraediaGttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkdknlviad ADAASRALTGS-EDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSglrvAEELVAAARERGSHDNITVMVVF | ..|.||.||..| .| | .. .| . | || . ||| |||||.|| pdiltfdlddhkpeflilasdGlwdtfsneeavrfikerlkepdfG----akslvlesfkrGsvdnitvlvvk |
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| Phosphatase | PPM1F.AA | Subfamily.PPM1K.PD | 191-412 | 36 | 2.8e-37 | 118.5 | In-house | 37-263 (264) | Show / Hide |
Range on Protein: 191-412
Range on HMM: 37-263/264
Sequence Identity: 36% (82 aa)
RAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFLRKAK-----RERLQSGTTGVCALI-AGATLHVAWLGDSQVILVQQGQ
||||||||||. || .. .... | | | | | .|| |. . | .. .| |.|||| .|. | | .| ||||. || ..|.
llyfavfdGhgGssaadfvhdkleeivrrllekekdleevlkqafeeldkklkrylefsvaeaellssGttatvsllrdGnelvlaslGdsrailcrnGk
VVKLMEPHRPERQDEKARIEALGGFVSH--MDCWRVNGTLAVSRAIGDVFQKPY-VSGEADAASRAL-TGSEDYLLLACDGFFDVVPHQEVVGLVQSHLT
|| . | |||..|| || | ||.|. .. .||. ||..|..||. |.| | . .. | . ... .|.| ||.|| ||. ||. ..
akkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkryGviatPetkslkvkhaadsflvlitdgisfvvnsqelcdlvrlchd
RQQgsglrVAEELVAAARERGSHDNITVMVVF
|. .. .| . ||.|| |..||
pee-----aahavteqalqygsednatavvvp
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| Phosphatase | PPM1F.AA | Subfamily.PPM1D.PD | 156-411 | 28 | 1.5e-30 | 96.6 | In-house | 9-311 (311) | Show / Hide |
Range on Protein: 156-411
Range on HMM: 9-311/311
Sequence Identity: 28% (85 aa)
LVSIHAIRNTRRKMEDRHVSLPSFNQLFGlsdPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPE----GALREAFRRTDQMFLR-------
|. .| . |. |||. . . .. . |..|||||||| .||..| |. .. .| .. .... |.|||| | .. ...
rvtseadqGgrkymeDvvaivlereesae---eaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpk
KAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQ------VVKLMEPHRPERQDEKARIEALGGFVSHM-----DCWRV-----NGT-------
. .||| . .| . |.|| |||...| .. . .|.. |.|| .|| ||| ||| |... .|. || |||
tksgllstaGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaaksGvkRvvWkRprlehngptvideiP
-LAVSRAIGDVF-----QKPY-VSGEADAASRALTGSED-YLLLACDGFFDVVPHQEVVGLVQSHLTRQQG---SGLRVAEELVAAARERGSH-----DN
.|..||.. .. | || | | | |...|. ...|| ||...|.. ...| .|... . .... ||. || | .| .. ||..|.||
FLavaRslGDlWsynaksgeyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealqrwrskklraDn
ITVMVV
vsvivv
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| Phosphatase | PPM1F.AA | Subfamily.PPM1G.PD | 247-394 | 41 | 7.4e-29 | 91.3 | In-house | 301-457 (482) | Show / Hide |
Range on Protein: 247-394 Range on HMM: 301-457/482 Sequence Identity: 41% (60 aa) KRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVShMDCwRVNGTLAVSRAIGDVFQKP---------YV . .|||| | ||. | .| || ||| .| ..|. . | |.|| . |..|||. || | .| |||| | .|||.|| . |.| | ..|| eepGkdsGttavvaLvkgkklivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvt-ldg-RvnGGLnlsRalGDhaYktneeLpaeeqmi SGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGS--GLRVAEELV ...| ||||| ..|. |||| |...|. .. | .. |||. salPDikklilteedeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLl |
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| Phosphatase | PPM1F.AA | Subfamily.PHLPP.PD | 264-411 | 25 | 3.2e-13 | 39.5 | In-house | 116-257 (257) | Show / Hide |
Range on Protein: 264-411 Range on HMM: 116-257/257 Sequence Identity: 25% (38 aa) GATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQ-DEKARIEALGGFVSHMDcwRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACDGF || .| |. ...|...|. . | . . | . .| || ... . .||| .. .| .| .| |.| . | || ...|.| ..... sftltaanvgkcklvlirnGkplplskvyileiddeelkrikeakaiitedn--kvnGviestrilGytflfPvvlPkphvrsvlLteqdEllilGnkal FDVVPHQEVVGLVqshltRQQGSGLRVAEELVAAARERGSHDNITVMVV |. .|.| | |.. . | .| || | | .|.....|| Wevlsideaveav-----rnvedplvaAkklvdlaqsygaadsvsalvv |
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| Phosphatase | PPM1F.AA | Subfamily.TAB1.PD | 250-333 | 34 | 2.6e-11 | 33.1 | In-house | 134-221 (336) | Show / Hide |
Range on Protein: 250-333 Range on HMM: 134-221/336 Sequence Identity: 34% (29 aa) RLQSGTTGVCALIAGATLHVAWLGDSQVILVQQG----QVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQ .. ||| | ||| |.|| .|||. |||.. .|..| | . .|| |.. || . .. .. | |.||| eisgGttavvalilnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdyki |
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| Phosphatase | PPM1F.AA | Subfamily.PPM1H.PD | 229-306 | 34 | 1.1e-10 | 31.0 | In-house | 140-215 (402) | Show / Hide |
Range on Protein: 229-306 Range on HMM: 140-215/402 Sequence Identity: 34% (27 aa) GALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERqdEKARIEAL ||| .|| . |.. | .. |.. | | . ||. |.|| |||. |||.......| . . || |. |. | GalesaflemDeqiarereayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadftPet--eRqRlqel |
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| Phosphatase | PPM1F.AA | Subfamily.PDP.PD | 334-383 | 36 | 2.5e-09 | 27.1 | In-house | 281-330 (409) | Show / Hide |
Range on Protein: 334-383 Range on HMM: 281-330/409 Sequence Identity: 36% (18 aa) KPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQ ||.. | . |. |. .. .|.|| || .|.. ..||| ||. ||.... PPYltaePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkk |
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| Phosphatase | PPM1F.AA | Subfamily.PPM1G.PD | 152-246 | 27 | 4.3e-08 | 22.9 | In-house | 7-94 (482) | Show / Hide |
Range on Protein: 152-246 Range on HMM: 7-94/482 Sequence Identity: 27% (26 aa) QRQWLVSIHAIRNTRRKMEDRHVSLPSFNQlfglsdpvNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPEL-PTDPEGALREAFRRTDQMFLRKA ... ... |. | ||| | .. ... . . |||.||||| . |.|.| .. . | | ||.||| |..| .. neelsygasamqGWRvsmeDahncildlde--------dtslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkklltee |
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| Phosphatase | PPM1F.AA | Subfamily.PDP.PD | 233-331 | 31 | 2.1e-07 | 20.7 | In-house | 145-251 (409) | Show / Hide |
Range on Protein: 233-331 Range on HMM: 145-251/409 Sequence Identity: 31% (34 aa) EAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQ---G--QVVKLMEPHRPERQDEKARIEALGGFVSH---MDCWRVNGTLAV ||...... |..| . ||.. ..||| | .|||| ||.. .| .| | ..||| . . . ..| ||.. . . |. |.|| ealkkleekvleeavlkvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLaP SRAIGDV .|| ||| lRAFGdv |
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| Phosphatase | PPM1F.AA | PP2C_SIG | 171-413 | 13 | 2.9e-07 | 28.84 | SMART | 1-250 (250) | Show / Hide |
Range on Protein: 171-413
Range on HMM: 1-250/250
Sequence Identity: 13% (40 aa)
DRHVSLPSFNQ---------LFGLSDPVN--RAYFAVFDGHG---GVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFLRKAKRERLQSGTT
|.|. . ... . .| | |.. |..| |. ||.... ..| . . . .. .|... . .. | .||
DDHWDIYQYYEDATQVCGDWYDFWKIPEGQDRYFFVIGDVMGWAHGLPAALMMGM-ARTMMRTFWHE------SPPQILERCNRWIYQN-NHEECGMFTT
GVCALI----AGATLHVAWLGDSQVILVQ--QGQVVKLMEP---------------HRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKP
.|... |..||... |.| . |. .|. | . . ... . . .|| .. |
MCCCVYMPDFATHTLWYCHCGHSPPYLYRAMDGGRVEHTHDHYLVQHYVMRIIDEEDAKHHPWHNWTGPPLGMEPDYM----------------------
YVSGEADAASRALTGSE-DYLLLACDGFFDVVPHQE-------VVGLVQSHLTRQQGSGLR-VAEELVAAARERGSHDNITVMVVFL
. .. .. . | .... || .... .|. . ... .|.. . . ..|| . . ... ||..||.|| .
-------YDVQEFQYEPGDRFVMCTDGVTEARNPQGEFFGEEWLQEILEEHQCCCPQEIAQRIMQELMEHMGDHNGHDDMTVIVVKV
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| Phosphatase | PPM1F.AA | Subfamily.PPTC7.PD | 218-287 | 25 | 7.5e-06 | 15.9 | In-house | 70-135 (263) | Show / Hide |
Range on Protein: 218-287 Range on HMM: 70-135/263 Sequence Identity: 25% (18 aa) ARQPELPTDPEGALREAFRRtdqmfLRKAKRERLQSGTTGVCALIAGA-TLHVAWLGDSQVILVQQGQVVK .. . ...|. |..|... |...|. .. | |. . .| . .|..| |||| .. | .|.|| keskfkerkpkkileaayqe-----lleekvpvvGsstacivvldredkklesaNlGDSgflVvRngkvvh |
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