PPM1F
Species: Human
Alias: KIAA0015, PPM1F, hFEM-2, FEM-2, CAMKP, POPX2, CaMKPase
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPM
Family: PPM
Subfamily: PPM1E
Protein domain

Protein domains of PPM1F.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase PPM1F.AA PP2Cc 144-411 27 6.2e-89 302.67 SMART 1-338 (338) Show / Hide
Range on Protein: 144-411
Range on HMM: 1-338/338
Sequence Identity: 27% (101 aa)

VPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTD-----------------
.. .  .|. .. ...... . |..|||.||  |               .|.||||||| ..|.|.. | | . |.... ..|                 
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP---------------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWW

----------PEGALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQ----------VVKLMEPHRPERQDEKARIEAL
          .| |||.||.|.|  .            .| |.||| | .|.||..|||...| ..|.          .. | | |.|...||..|||..
RMWHDKWFEDWEDALRKAFLRMDEEI------------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQA

GG--------FVSHMDC--WRVNGT---LAVSRAIGDVFQK------------------------PYVSGEADAASRAL------TGSEDYLLLACDGFF
||        .|.  .|  |||||.   ||||||.||.. |                        |||. | |  .. |      | . | |.|.||| .
GGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLW

DVVPHQEVVGLVQSHLT----------------------RQQGSGLRVAEELVAAARERGSHDNITVMVV
||...|||| .|...|.                      .. ..  ..|..|. .|.    .||.||.||
DVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----CDNMTVIVV

Phosphatase PPM1F.AA Subfamily.PPM1E.PD 145-413 59 8.49999999999e-129 418.6 In-house 2-269 (269) Show / Hide
Range on Protein: 145-413
Range on HMM: 2-269/269
Sequence Identity: 59% (160 aa)

PLAARaSQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFLR
||... ||... |||.|..|.|||||||||.|...|.||.|.|  .||.||||||||||.||.|||.|.|....||..|..||. ||.|||..||..||.
Plevk-sqkeyevsiaavknkrrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpaealkeafkltDerflq

KAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAA
||.||.|.||.|.|..||....|.||||||||..||..|..|.||.||.|||.|||.|||..||.| ....|||||.|.|||||||| .|||||||||.|
kaereklksGstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvigawRvnGvLsvsRaiGDvklkpyvsgeadva

SRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFL
. .|.||||||.|||||..|||...||| ||...|......  .||..||.||.|.||.|||||.||||
eveldgsedylilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvvvfl

Phosphatase PPM1F.AA PP2C 155-406 34 3.9e-101 347.09 Pfam 1-284 (284) Show / Hide
Range on Protein: 155-406
Range on HMM: 1-284/284
Sequence Identity: 34% (99 aa)

WLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVH----TNAARQPELPTD----PEGALREAFRR--TDQMFLR
| ........ |..|||.|...|..|.    |. .....|||||||||..||.|.. |.|    | .......|..    .| |||..|..  ||.|| .
WDYGFCRMQGWRHFMEDAHHCYPNMNCS--SSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYS

---KAKR----ERLQSGTTGVCALIAGAT--LHVAWLGDSQVILVQQGQVV----KLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGT-LAVSRAIGD
   ....    | ..||.| |||.| . .  |.||..|||...| ..|...     |.. |.|...||..||...||.|.....|||||. ||||||.||
APWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGD

VFQKP---------YVSGEADAA-SRALTGS-EDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNI
...||         .|. | |   .. .| . ...|.|||||..||...|||...|.....  . . ....|.||  ....||.|||
FHYKPNHTCFPKEQPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWN-DPMEACEKLVDYCIAYGSEDNI

Phosphatase PPM1F.AA Group.PPM.PD 147-416 38 1.2e-73 238.4 In-house 30-324 (459) Show / Hide
Range on Protein: 147-416
Range on HMM: 30-324/459
Sequence Identity: 38% (105 aa)

AARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFglsdpvnrAYFAVFDGHGGVDAARYAAVHVHTNAARQPELP-------------------TDP
.|.... ..... .. |..||||||.  .|..          ..|.|||||||  ||..|| . . . ..| .....|||.|| ..|. . ..|....  
ssagsgnglrygvasmqgwrkemEDrhvivenfdnnd--------sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekv

EGALREAFRRTDQMFLRKAKRER---LQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDcwRVNGTLAV
  .|||| |.||| | .|.||..|||...|...|..|.| . | ||...|. |||..||.|   .  ||||.||||||.||.  |     || | |  ..
kkalrsafleldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidg--RvnGilav

SRAIGDVFQKPY---VSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTR----QQGSGLRVAEELVAAARERGSH------DNITVMVV
 ||  ...| ||.|| .||.  .||| .|...|.     .. .   .||.|| .|...|||||||.||.| |                            
sRalGdhdlkkeeqmvsaePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgstgdgtscDNiTvivv

FLRDP
     
tlnda

Phosphatase PPM1F.AA Family.PPM.PD 150-415 36 1.3e-73 238.2 In-house 10-288 (495) Show / Hide
Range on Protein: 150-415
Range on HMM: 10-288/495
Sequence Identity: 36% (105 aa)

ASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFglsdpvNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELP-------------TDPEGALREAFR
.|.... ..... .  |..|||.|| . ....        . ..|.|||||||  ||..|| . | . ..| |               .. . |||.|| 
sssnglrygvasmqgwrsemeDahvvvenlenne------dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkafl

RTDQMFLRKAKRER--LQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHmDCWRVNGTLAVSRAIGDVFQK
..|. . .......   .|||| |..|| | .|.||..|||...|...|..|.| . | ||...|. |||..||.|.    .||||.||||||.||.. |
eldeelseelneksagkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvi-rdgrvnGvlavsRalGdfdlk

P----YVSGEADAASRALTGS-EDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRD
.    .|| | |  |  ||.. ...| ||.|| .||.  .||| ||...| ... .  ..||||| .| ..||.|||||.||.| .
keeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsrDNiTvlvvalye

Phosphatase PPM1F.AA Subfamily.PPM1A.PD 154-415 31 3.2e-58 187.5 In-house 9-281 (309) Show / Hide
Range on Protein: 154-415
Range on HMM: 9-281/309
Sequence Identity: 31% (87 aa)

QWLVSIHAIRNTRRKMEDRHVSLPSFNQlfglsDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQP--------ELPTDPEGALREAFRRTDQMFLRK
.  ... . .. |..||| |.   ....        . ..|||||||.| ....|.| |....  ..         .  .. . |||..|..|.   ...
glryglssmqgwRvemEDahtavidlps-----klkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekirkl

AKRER--LQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMdcwRVNGTLAVSRAIGDVFQKPY-------
. ..   .||.| |..|.   .| .| .|||  .|...|.||   | |.| ...|| |||. ||.|      ||||.||||||.|| . |          
velskgedksGsTavvvlvspkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmik---RvnGsLAvsRalGDydykekpekkate

--VSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQgSGLRVAEELVAAARERGSHDNITVMVVFLR-D
 ||.|.. .. . . ....|.||||| .||.  .||. .|.|.|....    .||.||.  . |.||.||..|..|.|    
qlvspepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtd-dleevanelldtcLekgsrDNmsvilvllpga

Phosphatase PPM1F.AA Subfamily.LRR-PP2C.PD 155-411 33 1.5e-49 158.8 In-house 10-255 (257) Show / Hide
Range on Protein: 155-411
Range on HMM: 10-255/257
Sequence Identity: 33% (87 aa)

WLVSIHAIRNTRRKMEDRHVSLPSFNqlfglsDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPEL-PTDPEGALREAFRRTDQMFlrkAKRErLQS
. |.   .   |  |||. |   ||.      |  .  |.|.|||||| .||..|. ...   |   .| ...|. .|..|.. .. ..   ..|     
fkvgfsdmiGrrptmedelviyGsfr------dksdedyyalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqi---serp-kfi

GTTGVCALIAGATLHVAWLGDSQVILV-QQGQVVKLMEPHRPERQDEKARIEALGGFVSHM-DCWRVNGTLAVSRAIGDVFQKPYVSGEADAA-SRALTG
||| . .|| .    .| .|||.|.|  ..|  ..|   |.|  ..|. ||..|||.|       |||||||||||.||.| .|.|  . |   |   . 
GttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsflePfvvpdPdlsqsleisk

SEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQqgsglRVAEELVAAARERGSHDNITVMVV
.. .|.||||| .|..  .| | .| .    .     . ||.|   | ..|| |||.|.|.
kdkflilacdGiwdlisdeeaveivagisdpe-----kaaeklrdlayssGstdnisvivi

Phosphatase PPM1F.AA Subfamily.PPM1G2.PD 152-411 35 2.1e-49 158.3 In-house 7-275 (275) Show / Hide
Range on Protein: 152-411
Range on HMM: 7-275/275
Sequence Identity: 35% (96 aa)

QRQWLVSIHAIRNTRRKMEDRHVSLPSfnqLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTD-PEGALREAFRRTDQMFLRKAKRER
. .  |.. ...  | .||| |.  .    |. .||  . |.||||||||| ..|.||. ...   |.....  .  | .|..|| .||..|.. | .  
nariavgvssmqGyrlnmeDahilene---lleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdeklkd

LQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMdcwRVNGTLAVSRAIGDV-FQKPY--------VSGEA
..|.| | .||    | ||  |||. .| ..|.| .|   |.|....|| ||.| ||||.     ||||.||.|||.|||.|          |  . |  
esaGstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfveln---rvngnLalsralgDfefkknvkkkpeeqivtavP

DAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQgSGLRVAEELVAAARERGSH------DNITVMVV
 . |. ....|.||||| .||.  .||| ||...|.... .  ...|||.  .  . |.      ||.||..|   
DvlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsga-kldeiieelldkclapdssntgvGcDnmtvviv

Phosphatase PPM1F.AA Subfamily.ILKAP.PD 154-411 31 8.2e-46 146.8 In-house 7-298 (298) Show / Hide
Range on Protein: 154-411
Range on HMM: 7-298/298
Sequence Identity: 31% (91 aa)

QWLVSIHAIRN-TRRKMEDRHVSLPSFNQLFGLSDP--VNRAYFAVFDGHGGVDAARYAAVHVHTNAAR------QPELPTDPEGALREAFRRTDQMFLR
| . .| |.  |..||| || |  ...    ...   . .|.||||||.|  |...|| ..| .  .      . .  .. . .|..||..||. ||..|
yklegafaerkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflk

KAKR--ERLQSGTTGVCALIAGATLHVAWLGDSQVILVQ---QGQ--------VVKLMEPHRPERQDEKARIEALGGFVSHMdcwRVNGTLAVSRAIGDV
..     ..|.|.|..|. . .|.|| ||||. .|.    .|.        .| | . | |  ..|. ||.  ||.| .||.| |.|||.|||  |..  
laskakPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdg---RvlGvlevsRsiGDg

-FQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQ--------QG-SGL----R-VAEELVAAARERGSHDNITVMVV
|. . |     ||  . ...||||| ..|.  .|||  ... |  .        .| |      . ..| | . | .||| ||.||..|      
rfkelgvistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlededdrkikqeegksaeevrfevacerlAseavkrgssDnvtvllv

Phosphatase PPM1F.AA Subfamily.PPM1L.PD 153-412 32 2.4e-41 132.1 In-house 10-272 (273) Show / Hide
Range on Protein: 153-412
Range on HMM: 10-272/273
Sequence Identity: 32% (87 aa)

RQWLVSIHAIRNTRRKMEDRhvslpsFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHV------HT---NAARQPELPTDPEGALREAFRRTDQMFL
..  |......  | .||||      |.   .... ..  .|||||||||  || .|   .      .    .|... ..| . .  | .|. .| ||||
kkqnvavysvlGrrprmedr------feieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekll

RKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILV-QQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVF--QKPYVSGE
.   .||| . ||...  | || .|||. .|. ..|. . |   |.|..  |. ||.  |||..   .|||.| ||.|||.||    .|  |  . |  .
ekakraediaGttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplkdknlviad

ADAASRALTGS-EDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSglrvAEELVAAARERGSHDNITVMVVF
  |     ..|.||.||..|    .| |  .. .|   .      |  ||  .  ||| |||||.||      
pdiltfdlddhkpeflilasdGlwdtfsneeavrfikerlkepdfG----akslvlesfkrGsvdnitvlvvk

Phosphatase PPM1F.AA Subfamily.PPM1K.PD 191-412 36 2.8e-37 118.5 In-house 37-263 (264) Show / Hide
Range on Protein: 191-412
Range on HMM: 37-263/264
Sequence Identity: 36% (82 aa)

RAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFLRKAK-----RERLQSGTTGVCALI-AGATLHVAWLGDSQVILVQQGQ
||||||||||. || ..  ....   |  |   | |  | .||   |. . | ..     .| |.||||   .|.  |  | .| ||||. || ..|.  
llyfavfdGhgGssaadfvhdkleeivrrllekekdleevlkqafeeldkklkrylefsvaeaellssGttatvsllrdGnelvlaslGdsrailcrnGk

VVKLMEPHRPERQDEKARIEALGGFVSH--MDCWRVNGTLAVSRAIGDVFQKPY-VSGEADAASRAL-TGSEDYLLLACDGFFDVVPHQEVVGLVQSHLT
|| . | |||..|| || | ||.|.   ..  .||. ||..|..||.  |.| |  . .. |  .  ... .|.|  ||.||  ||.  ||.     .. 
akkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkryGviatPetkslkvkhaadsflvlitdgisfvvnsqelcdlvrlchd

RQQgsglrVAEELVAAARERGSHDNITVMVVF
     |. .. .| . ||.|| |..||     
pee-----aahavteqalqygsednatavvvp

Phosphatase PPM1F.AA Subfamily.PPM1D.PD 156-411 28 1.5e-30 96.6 In-house 9-311 (311) Show / Hide
Range on Protein: 156-411
Range on HMM: 9-311/311
Sequence Identity: 28% (85 aa)

LVSIHAIRNTRRKMEDRHVSLPSFNQLFGlsdPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPE----GALREAFRRTDQMFLR-------
|. .| .  |. |||. .   . ..        . |..|||||||| .||..|  |. ..  .| .. ....     |.||||  | ..       ... 
rvtseadqGgrkymeDvvaivlereesae---eaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpk

KAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQ------VVKLMEPHRPERQDEKARIEALGGFVSHM-----DCWRV-----NGT-------
.   .|||  . .| .  |.||  |||...| .. .        .|.. |.||  .|| ||| ||| |...      .|.      ||         |||
tksgllstaGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaaksGvkRvvWkRprlehngptvideiP

-LAVSRAIGDVF-----QKPY-VSGEADAASRALTGSED-YLLLACDGFFDVVPHQEVVGLVQSHLTRQQG---SGLRVAEELVAAARERGSH-----DN
.|..||..     .. | || | |   | |...|. ...|| ||...|.. ...| .|... . ....  ||. ||  | .| ..     ||..|.||  
FLavaRslGDlWsynaksgeyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqsrsvakalvkealqrwrskklraDn

ITVMVV
      
vsvivv

Phosphatase PPM1F.AA Subfamily.PPM1G.PD 247-394 41 7.4e-29 91.3 In-house 301-457 (482) Show / Hide
Range on Protein: 247-394
Range on HMM: 301-457/482
Sequence Identity: 41% (60 aa)

KRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVShMDCwRVNGTLAVSRAIGDVFQKP---------YV
.  .|||| | ||. | .| ||  |||  .| ..|. . |   |.|| . |..|||. || |  .|  |||| | .|||.|| . |.|   |   ..|| 
eepGkdsGttavvaLvkgkklivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvt-ldg-RvnGGLnlsRalGDhaYktneeLpaeeqmi

SGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGS--GLRVAEELV
 ...| ||||| ..|.  ||||  |...|. .. |    .. |||.             
salPDikklilteedeFlvlacDGiWnvmssqevvdFvraklkeseeskklseiceeLl

Phosphatase PPM1F.AA Subfamily.PHLPP.PD 264-411 25 3.2e-13 39.5 In-house 116-257 (257) Show / Hide
Range on Protein: 264-411
Range on HMM: 116-257/257
Sequence Identity: 25% (38 aa)

GATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQ-DEKARIEALGGFVSHMDcwRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACDGF
|| .|  |. ...|...|. . | . .  | . .|  ||    ...   .  .||| .. .| .| .|  |.|  .    |  ||  ...|.|  .....
sftltaanvgkcklvlirnGkplplskvyileiddeelkrikeakaiitedn--kvnGviestrilGytflfPvvlPkphvrsvlLteqdEllilGnkal

FDVVPHQEVVGLVqshltRQQGSGLRVAEELVAAARERGSHDNITVMVV
|.  .|.|  |     |.. . | .|  ||  |   | .|.....||  
Wevlsideaveav-----rnvedplvaAkklvdlaqsygaadsvsalvv

Phosphatase PPM1F.AA Subfamily.TAB1.PD 250-333 34 2.6e-11 33.1 In-house 134-221 (336) Show / Hide
Range on Protein: 250-333
Range on HMM: 134-221/336
Sequence Identity: 34% (29 aa)

RLQSGTTGVCALIAGATLHVAWLGDSQVILVQQG----QVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQ
.. ||| | |||    |.|| .|||. |||..     .|..|   |  . .||  |.. ||  . ..   .. |     |.|||    
eisgGttavvalilnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrlgskeaTRsiGdyki

Phosphatase PPM1F.AA Subfamily.PPM1H.PD 229-306 34 1.1e-10 31.0 In-house 140-215 (402) Show / Hide
Range on Protein: 229-306
Range on HMM: 140-215/402
Sequence Identity: 34% (27 aa)

GALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERqdEKARIEAL
||| .|| . |..  |  .. |.. | | . ||.    |.||  |||. |||.......| . . ||   |. |.  |
GalesaflemDeqiarereayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadftPet--eRqRlqel

Phosphatase PPM1F.AA Subfamily.PDP.PD 334-383 36 2.5e-09 27.1 In-house 281-330 (409) Show / Hide
Range on Protein: 334-383
Range on HMM: 281-330/409
Sequence Identity: 36% (18 aa)

KPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQ
||.. | .  |. |. .. .|.|| || .|.. ..||| ||. ||.... 
PPYltaePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkk

Phosphatase PPM1F.AA Subfamily.PPM1G.PD 152-246 27 4.3e-08 22.9 In-house 7-94 (482) Show / Hide
Range on Protein: 152-246
Range on HMM: 7-94/482
Sequence Identity: 27% (26 aa)

QRQWLVSIHAIRNTRRKMEDRHVSLPSFNQlfglsdpvNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPEL-PTDPEGALREAFRRTDQMFLRKA
...  ... |.   |  ||| | ..  ...        . . |||.||||| . |.|.| ..      .      | | ||.|||   |..| .. 
neelsygasamqGWRvsmeDahncildlde--------dtslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkklltee

Phosphatase PPM1F.AA Subfamily.PDP.PD 233-331 31 2.1e-07 20.7 In-house 145-251 (409) Show / Hide
Range on Protein: 233-331
Range on HMM: 145-251/409
Sequence Identity: 31% (34 aa)

EAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQ---G--QVVKLMEPHRPERQDEKARIEALGGFVSH---MDCWRVNGTLAV
||......  |..|  .   ||.. ..||| | .||||  ||.. .| .|   |  ..||| . .  . ..|  ||..      .   .   |. |.|| 
ealkkleekvleeavlkvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLaP

SRAIGDV
.|| |||
lRAFGdv

Phosphatase PPM1F.AA PP2C_SIG 171-413 13 2.9e-07 28.84 SMART 1-250 (250) Show / Hide
Range on Protein: 171-413
Range on HMM: 1-250/250
Sequence Identity: 13% (40 aa)

DRHVSLPSFNQ---------LFGLSDPVN--RAYFAVFDGHG---GVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFLRKAKRERLQSGTT
|.|.  . ...          .   .|    |  |.. |..|   |. ||....  ..|    .  .       . .. .|... . ..   |    .||
DDHWDIYQYYEDATQVCGDWYDFWKIPEGQDRYFFVIGDVMGWAHGLPAALMMGM-ARTMMRTFWHE------SPPQILERCNRWIYQN-NHEECGMFTT

GVCALI----AGATLHVAWLGDSQVILVQ--QGQVVKLMEP---------------HRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKP
 .|...    |..||...  |.| . |.   .|. |   .                 .  ... . .  .|| ..  |                      
MCCCVYMPDFATHTLWYCHCGHSPPYLYRAMDGGRVEHTHDHYLVQHYVMRIIDEEDAKHHPWHNWTGPPLGMEPDYM----------------------

YVSGEADAASRALTGSE-DYLLLACDGFFDVVPHQE-------VVGLVQSHLTRQQGSGLR-VAEELVAAARERGSHDNITVMVVFL
       . .. ..  . | .... || .... .|.       . ... .|..   .   .  ..|| . . ... ||..||.|| .
-------YDVQEFQYEPGDRFVMCTDGVTEARNPQGEFFGEEWLQEILEEHQCCCPQEIAQRIMQELMEHMGDHNGHDDMTVIVVKV

Phosphatase PPM1F.AA Subfamily.PPTC7.PD 218-287 25 7.5e-06 15.9 In-house 70-135 (263) Show / Hide
Range on Protein: 218-287
Range on HMM: 70-135/263
Sequence Identity: 25% (18 aa)

ARQPELPTDPEGALREAFRRtdqmfLRKAKRERLQSGTTGVCALIAGA-TLHVAWLGDSQVILVQQGQVVK
..  . ...|.  |..|...     |...|. .. | |. . .| .   .|..| |||| .. | .|.|| 
keskfkerkpkkileaayqe-----lleekvpvvGsstacivvldredkklesaNlGDSgflVvRngkvvh

Sequence
Name Sequence Type Origin Length Description Download
PPM1F.AA Protein None 454 None Fasta, JSON
PPM1F.NA RNA None 1362 None Fasta, JSON
PPM1F.AA.PD_144-413 Protein Phosphatase Domain None 270 None Fasta, JSON