PPM1G
Species: Human
Alias: PPM1G, PP2CGAMMA, PPP2CG, MGC2870, MGC1675, PP2CG
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPM
Family: PPM
Subfamily: PPM1G
Protein domain

Protein domains of PPM1G.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase PPM1G.AA PP2Cc 15-503 19 4.5e-106 359.61 SMART 1-338 (338) Show / Hide
Range on Protein: 15-503
Range on HMM: 1-338/338
Sequence Identity: 19% (111 aa)

GDGVGAPRLPLPYGF--SAMQGWRVSMEDAHNCIPELDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEG------------------------
 . .| .   . ||.  |.|||||..||||| |.|       .| |.||||| |.| ||.| |..... ..  ...                        
HS-MGYNSG-WRYGYMESSMQGWRHPMEDAHVCRP-------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHDKW

--KLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGL
  .. .||..|||..| ..                                                                                 
FEDWEDALRKAFLRMDEEI---------------------------------------------------------------------------------

NGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSS
                                                                                                    
----------------------------------------------------------------------------------------------------

EEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGK----------ALDMSYDHKPEDEVELAR
                                          .|||||||||..|.|||.||||.|.. .|.          |.....||||..|.|..|
------------------------------------------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRR

IKNAGGK-------VTMDG-----RVNGG---LNLSRAIGDHFYKRNK----------------NLPPEEQMISALPDIKVLTL------TDDHEFMVIA
|..|||.       . |..     ||||    |..|||.|||.||. |                .||..|....|.||... .|      |.|..|....
IEQAGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKW-KEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILC

CDGIWNVMSSQEVVDFIQSKISQRDENGEL------------------RLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIII
|||.|.|||.|||||.... ......  ..                    .... ..| |...          |||||.|..
CDGLWDVMSNQEVVDIVRKCLRKWHHK-PVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----------CDNMTVIVV

Phosphatase PPM1G.AA Subfamily.PPM1G.PD 19-505 59 2e-223 733.0 In-house 4-482 (482) Show / Hide
Range on Protein: 19-505
Range on HMM: 4-482/482
Sequence Identity: 59% (288 aa)

GAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIA
....  |.||.||||||||||||||||| .||..|..|.|||||||.||| ||||.|||..|..||||||...||||.|||..|.||.|||..|||..||
desneelsygasamqGWRvsmeDahncildldedtslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkkllteeilkelkeia

GRPTEDEDEKEkvadedDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNS
|...|...|||      |...|||. |.|||....||||..|.....| ....||..|..|.  |. .. || .|.|.||....|.  ..|.....|...
geekeegeeke------deeeeeaerlteeaelpleellekykelkkkkdldlksadgseesevsaaaakeaaseesereedneeeeeegkdseeksken

ERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGME
|. ||.....|... . |......||..|| ..||.|.|||.|.|||||.||||||....|||...||||||.|||||..||.|||.|||.|........
elktenaelkeeeeeeeeeeeeeesakeklvseakkklfeddeeesdeadeeeedskdskeeeeeesseeaedeedededeeeeedeeeededelaedll

GK-EEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQM
|| ||||.||||||||||..||.||||||||||||.|..|||||.|.||||||||||.||..||||||.|||||||||||||.|||.||.|..||.||||
gkseepGkdsGttavvaLvkgkklivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeLpaeeqm

ISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENgelRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICF
||||||||.|.||...||.|.|||||||||||||||||...|.....|.   . ||.|.|||||.|||||||||||||||||..|. .
isalPDikklilteedeFlvlacDGiWnvmssqevvdFvraklkesees---kklseiceeLlDaCLapdtsgDGtGCDnmtvvivql

Phosphatase PPM1G.AA Group.PPM.PD 21-533 46 1.1e-111 363.8 In-house 34-349 (459) Show / Hide
Range on Protein: 21-533
Range on HMM: 34-349/459
Sequence Identity: 46% (149 aa)

PRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAklttEEvikelaqiagr
. .| ||...||||| .|||.|... ..|.....|.|.|||||.|.| ..|| ||.|.| |. .|. ...|. ..|.|. |      ..|. .. .|.|.
sgnglrygvasmqgwrkemEDrhvivenfdnndsffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldndd----rg-----------

ptededekekvadeddvdneeaallheeatmtieelltrygqnchkgpphsksgggtgeepgsqglngeagpedstretpsqengptakaytgfssnser
|. || |.||.|.||||.|||||||||||.||.|.||||||||.|....||| ..|.|||||.. |  ||..|||.|..||||||.|..|||.||| .|.
----------------------------------------------------------------------------------------------------

gteagqvgepgiptgeagpscssasDKLPRVAKSKFFEDSEDESDEAEEEEedseecseeedgysseeaeneededdteeaeeddeeeeeemmvpgmegk
||||.|| ||..|..||...||.|.|.||.|.|.|..|||.|........... .   |..| |.|.|..||. .| ||||.|||.|.|.....     .
-------------------------ekvkkalrsafleldedlseeaneke-------------------------------------------------

eEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRnknlppEEQMISA
|.  .....||| |..  ||.                                                                               
-epgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidgRvnGilavsRalGdhdlkk------eeqmvsa

LPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENgELRLLSSIVEELLDQCLAP-DTsGDGTGCDNMTCIIICFKPRNTAELQPESGK
                                                                                                    
ePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkke-lkkdleeiaerlvdealakgst-gdgtscDNiTvivvtlndamrrqleivkke

RKLEEVLSTEGAEE
              
evleeelafmvael

Phosphatase PPM1G.AA Family.PPM.PD 22-529 42 3.3e-98 319.3 In-house 12-310 (495) Show / Hide
Range on Protein: 22-529
Range on HMM: 12-310/495
Sequence Identity: 42% (128 aa)

RLPLPYGFSAMQGWRVSMEDAHNCIPELDS--ETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEgklqkaledaF----------Laidaklttee
. .| ||...||||| .|||||... .|..  ....|.|.|||||.|.| ..|| |..|.|.|. .|..|. .. ...|.|. |. |.|..|...|.|||
snglrygvasmqgwrsemeDahvvvenlennedfslfgvfDGhgGaeaaefaakklhkilkkqlekkd----------deksstsaessa----------

vikelaqiagrptededekekvadeddvdneeaallheeatmtieelltrygqnchkgpphsksgggtgeepgsqglngeagpedstretpsqengptak
|||||.|||||.|.||||||||.|....||| ..|.|||||.. |  ||..|||||.. ||||||.|..|||.||...|.      |||. .|| |||..
----------------------------------------------------------------------------------------------------

aytgfssnsergteagqvgepgiptgeagpscssasDKLPRVAKSKFFEDSEDESDEAEEEEedseecseeedgysseeaeneededdteeaeeddeeee
..|| ...||.|.|.||.|.|.|..|||.......     . .   |..| |||.|..||....      ||.|.......     . .    |..|.. 
------------------------------------ekvkealrkafleldeelseelneks--------------------------------------

eemmvpgmegkeePGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM-DGRVNGGLNLSRAIGDHFYKRn
.||                                                                                                 
-------------agkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvirdgrvnGvlavsRalGdfdlkk-

knlppEEQM-ISALPDIKVLTLT-DDHEFMVIACDGIWNVMSSQEVVDFIQSKIsqrdeNGELRLLSSIVEELLDQCLAPDTSgdgtgcDNMTCIIICFK
                                                                                                    
-----eeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretl-----eekeedleeiaeeLvdealakgsr------DNiTvlvvaly

PRNTAELQPESGKRKLEEVLSTE
                       
enikqqnrfvlnknslmtrrstf

Phosphatase PPM1G.AA Subfamily.PPM1G2.PD 324-503 50 1.5e-68 221.0 In-house 103-275 (275) Show / Hide
Range on Protein: 324-503
Range on HMM: 103-275/275
Sequence Identity: 50% (90 aa)

GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDgRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPD
...|.||||.||. ..|.||||||||.|.|..|..  .|.||||..| |  ||..||| | .. |||| | ||||.||. .|.|....||||.. |.||.
desaGstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfveln-rvngnLalsralgDfefkknvkkkpeeqivtavPD

IKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDEngelrlLSSIVEELLDQCLAPDTSGDGTGCDNMTCIII
 |  |..|.||.|.||||||.|....||||......... .      |..|.|||||.|||||.|  | ||||||..|. 
vlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgak------ldeiieelldkclapdssntgvGcDnmtvviv

Phosphatase PPM1G.AA PP2C 325-492 41 2.6e-67 234.75 Pfam 112-284 (284) Show / Hide
Range on Protein: 325-492
Range on HMM: 112-284/284
Sequence Identity: 41% (74 aa)

SDSGTTAVVALIRGKQ--LIVANAGDSRCVVSEAGKAL----DMSYDHKPEDEVELARIKNAGGKVTM--DGRVNGG-LNLSRAIGDHFYKRNKNLPPEE
..||.|||.|.||...  |.|||.||||.|.. .|.|      ..|||||..| | .||..||| |     .||||  |..|||.||..|| |....|.|
WHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGDFHYKPNHTCFPKE

QMISALPDIK-VLTLTDD-HEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDG
|...| |||  . ..|.| .||...||||.|.|||.|||.|.... .|. .       .. . |.|.| |.|. .. ..
QPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWN------DPMEACEKLVDYCIAYGSEDNI

Phosphatase PPM1G.AA Subfamily.PPM1A.PD 318-512 40 2.1e-61 197.9 In-house 104-287 (309) Show / Hide
Range on Protein: 318-512
Range on HMM: 104-287/309
Sequence Identity: 40% (79 aa)

EGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMdGRVNGGLNLSRAIGDHFYKRNKNLPPEEQM
...    ||.||||.|.. |.|..||.|||| |.|..||.  ...|||| |. |  ||.||||.|.. .|||| | .|||.||..||........||..|
velskgedksGsTavvvlvspkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmi-kRvnGsLAvsRalGDydykekpekkateql

ISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDEngelrlLSSIVEELLDQCLAPDTSgdgtgcDNMTCIIICF--KPRNTAE
. |...|.. ....||.|.|||||| |||..||..|..|...  |.      |.....||||.||  ..       |||..|....   |. . |  
vspepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtdd------leevanelldtcLekgsr------DNmsvilvllpgapkvsee

Phosphatase PPM1G.AA Subfamily.PPM1E.PD 288-476 32 5.7e-38 120.8 In-house 73-250 (269) Show / Hide
Range on Protein: 288-476
Range on HMM: 73-250/269
Sequence Identity: 32% (62 aa)

EAENEEDEDDTEEAEEDDEEEEEEMMVPGMegkEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMD
....|....|..|| ..  .. .|...      |. .  ||.||||.||...|| ||  |||. .. . |.|. .   ||||.| | .||..||| | . 
lvrqeklkedpaealkeafkltDerflqka---ereklksGstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvi

G--RVNGGLNLSRAIGDHFYKrnknlppeeQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENgELRLLSSIV
|  |||| |..||||||  .|         ...|. .|.  ..|.........||||.|.|.  .|||. ... ...  |.. ..  ..| 
gawRvnGvLsvsRaiGDvklk---------pyvsgeadvaeveldgsedylilacDGlwDvvneeevvklveefladgaed-lsevakllv

Phosphatase PPM1G.AA Subfamily.ILKAP.PD 320-502 35 1.2e-33 106.8 In-house 110-297 (298) Show / Hide
Range on Protein: 320-502
Range on HMM: 110-297/298
Sequence Identity: 35% (69 aa)

KEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVS---EAGK--------ALDMSYDHKPEDEVELARIKNAGGKVTmDGRVNGGLNLSRAIGDHFYKRN
|..|   .|.||||.|. .  | ||| |||. |.    |.|.        .. .|.||.| .. |  ||..||| |. ||||.| |. ||.|||  .|. 
kakPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvr-dgRvlGvlevsRsiGDgrfkel

KnlppeeqmISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRD-ENGELRLLSSIVE---ELLDQCLAPDTSGDGTGcDNMTCII
         ... ||.| ..||..  |.|.||||.|.|.. .|||.||.. . ..| .. . .   |  |   |.  . ||..   |.. ||.| .. 
g--------vistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlededdrkikqeegksaeevrfevacerlAseavkrgss-Dnvtvll

Phosphatase PPM1G.AA Subfamily.PPM1L.PD 326-462 45 7e-33 104.3 In-house 112-245 (273) Show / Hide
Range on Protein: 326-462
Range on HMM: 112-245/273
Sequence Identity: 45% (61 aa)

DSGTTAVVALIRGKQLIVANAGDSRCVVS-EAGKALDMSYDHKPEDEVELARIKNAGGKVTMDG--RVNGGLNLSRAIGDHFYKrNKNlppeeqMISALP
.||||..||.....||||| |||| |.  . |||. .|.||||..  |  |||.||| ....|  ||.| | .|||.||.  | .||.. | |||  . |
iaGttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk-dkn------lviadp

DIKVLTLTDD-HEFMVIACDGIWNVMSSQEVVDFIQSKISQ
 |   ||...|.||.|. .| .| | ||. ....       
diltfdlddhkpeflilasdGlwdtfsneeavrfikerlke

Phosphatase PPM1G.AA Subfamily.LRR-PP2C.PD 325-464 39 1.6e-32 102.9 In-house 97-231 (257) Show / Hide
Range on Protein: 325-464
Range on HMM: 97-231/257
Sequence Identity: 39% (54 aa)

SDSGTTAVVALIRGKQLIVANAGDSRCVVS-EAGKALDMSYDHKPEDEVELARIKNAGGKVTMD---GRVNGGLNLSRAIGDHFYKrnknlpPeeqMISA
||||...|| ... ..|| |||| |..   | |  .|.|||| .| |  ||...||.|  .    |||| | .|||.|| | .|    . . ||..  |.
kfiGttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsfle------P---fvvp

LPDIK-VLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSkISQRD
 . ...|...||||||...| .| |. . . ||. .         
dPdlsqsleiskkdkflilacdGiwdlisdeeaveivag-isdpe

Phosphatase PPM1G.AA Subfamily.PPM1K.PD 325-458 40 2e-27 86.2 In-house 102-233 (264) Show / Hide
Range on Protein: 325-458
Range on HMM: 102-233/264
Sequence Identity: 40% (52 aa)

SDSGTTAVVALIR-GKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMD----GRVNGGLNLSRAIGDHFYKRNKnlppeeqmIS
.||||| |.|.| |..|..|. |||| ..   |||  .. ||.|| . |  |||.|||.|...     .||. | ..|..||   ||. | |. | | . 
lssGttatvsllrdGnelvlaslGdsrailcrnGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkryG--------vi

ALPDIKVLTL-TDDHEFMVIACDGIWNVMSSQEVVDFIQS
 ..  |.|.  ||| .|..|||. |...            
atPetkslkvkhaadsflvlitdgisfvvnsqelcdlvrl

Phosphatase PPM1G.AA Subfamily.PPM1G2.PD 27-113 46 2.3e-27 86.0 In-house 12-103 (275) Show / Hide
Range on Protein: 27-113
Range on HMM: 12-103/275
Sequence Identity: 46% (42 aa)

YGFSAMQGWRVSMEDAHNCIPEL-----DSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKE
| |.|||.|..|||||   .||     |...|.|.|.|||||..|| |..| |  .|. .|..|||.|...|.||||..| .|. .| .|. 
vgvssmqGyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdeklkd

Phosphatase PPM1G.AA Subfamily.PDP.PD 326-468 30 1.2e-23 74.3 In-house 164-334 (409) Show / Hide
Range on Protein: 326-468
Range on HMM: 164-334/409
Sequence Identity: 30% (51 aa)

DSGTTAVVALIRGKQLIVANAGDSRCVVS---EAG--KALDMSYDHKPEDEVELARIKNAGG-----KVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEE
||..|..|||.|..| |||.||.|.|.    | |  .|  .| |.  . | |. |||..        | ..||. | |  .|| ||  || .|.|  .  
lsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLaPlRAFGdvryKwskelqkkv

-------Q-----------MISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGE
      .            ..| |..    |. .  |.|.| ||.|...|..|||. ..  ....... . 
lekllevkvvepkdyktPPYltaePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkknkak

Phosphatase PPM1G.AA Subfamily.PPM1A.PD 25-112 38 1.8e-23 73.3 In-house 10-107 (309) Show / Hide
Range on Protein: 25-112
Range on HMM: 10-107/309
Sequence Identity: 38% (37 aa)

LPYGFSAMQGWRVSMEDAHNCIPELDS---ETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAY-------KEGKLQKALEDAFLAIDAKLTTEEVIK
| || |.||||||.||||| .. .| |   . . |.|.|||.|..|. |||| | ..| .....       .. |...||...||..| |...  .. 
lryglssmqgwRvemEDahtavidlpsklkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekirklvels

Phosphatase PPM1G.AA PP2C 25-102 39 2e-19 71.51 Pfam 1-93 (284) Show / Hide
Range on Protein: 25-102
Range on HMM: 1-93/284
Sequence Identity: 39% (37 aa)

LPYGFSAMQGWRVSMEDAHNCIP------ELDSETAMFSVYDGHGGEEVALYCAKYLP----DIIKDQKAYKEG---KLQKALEDAFLA--ID
. |||..||||| .||||| |.|      . ... . | |.||||| ..| ||.| |.    .|.| .| ..||   ....|| ..||.  .|
WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTD

Phosphatase PPM1G.AA Subfamily.TAB1.PD 326-454 34 6.1e-16 48.4 In-house 136-274 (336) Show / Hide
Range on Protein: 326-454
Range on HMM: 136-274/336
Sequence Identity: 34% (48 aa)

DSGTTAVVALIRGKQLIVANAGDSRCVVSEAG----KALDMSYDHKPEDEVELARIKNAG---GKVTMDGRVnGGLNLSRAIGDH----FYKRNKNLPP-
|||||||||  ..| ||| |||| .. |      |.  .| ||  . | || |.|. |   ...   .|. |. .  |.|||.     ||.. |   ...
sgGttavvalilnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrl-gskeaTRsiGdykikkgykevdvlssA

EEQMISALPDIKVLTLTDDHE-FMVIACDGIWNVMssQEVVD
 | | |||.     .| | |...  ||. . .   |. .   
kgePiiatPdingpkdindlegfllLmSdGlykal--ieltn

Phosphatase PPM1G.AA Subfamily.PHLPP.PD 340-457 28 3.4e-15 46.0 In-house 118-227 (257) Show / Hide
Range on Protein: 340-457
Range on HMM: 118-227/257
Sequence Identity: 28% (34 aa)

QLIVANAGDSRCVVSEAGKALDMSYDHKPEDE-VELARIKNAGGKVTMDGRVNGGLNLSRAIGdHFYKRNKNLPPeeqmisalPDIKVLTLTDDHEFMVI
| .||.|. . |.   || | .|  .  | .  || |||.| . .| |..||| .. .| .| ...     ||         | .. ..||.. |.... 
tltaanvgkcklvlirnGkplplskvyileiddeelkrikeakaiitednkvnGviestrilG-ytflfPvvlPk--------phvrsvlLteqdEllil

ACDGIWNVMSSQEVVDFIQ
 ...|.|.| .|.|. .. 
GnkalWevlsideaveavr

Phosphatase PPM1G.AA Subfamily.PPM1D.PD 324-387 39 1.5e-13 40.8 In-house 111-180 (311) Show / Hide
Range on Protein: 324-387
Range on HMM: 111-180/311
Sequence Identity: 39% (27 aa)

GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGK------ALDMSYDHKPEDEVELARIKNAGGKVTMD
| .|||| | .||...| ||. |||. |..   .      |  .  |||||.  |  ||...||.|..  
lstaGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaak

Phosphatase PPM1G.AA Subfamily.PPM1K.PD 28-107 34 2e-13 40.3 In-house 13-90 (264) Show / Hide
Range on Protein: 28-107
Range on HMM: 13-90/264
Sequence Identity: 34% (27 aa)

GFSAMQGWRVSMEDAHnCIPELDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKaYKEGKLQKALEDAFLAIDAKLTT
|. ...| |   ||   .. ||| .   |.|.|||||   | .. . |  |... .  ||  |.. | .||. .| ||. 
GkdsliGkraenedrf-klkeldpdllyfavfdGhgGssaadfvhdkleeivrrll-ekekdleevlkqafeeldkklkr

Phosphatase PPM1G.AA Subfamily.PPM1E.PD 30-108 34 6e-13 38.7 In-house 16-101 (269) Show / Hide
Range on Protein: 30-108
Range on HMM: 16-101/269
Sequence Identity: 34% (29 aa)

SAMQGWRVSMEDAHNCIPEL----D----SETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLqKALEDAFLAIDAKLTTE
|... |  ||| | ....|    .    .| |.|.|.||||| | | | |. |.  . .|.  ||  . .||..|| ..| ....  
aavknkrrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa-ealkeafkltDerflqk

Phosphatase PPM1G.AA Subfamily.PPM1D.PD 394-503 26 7.9e-13 38.4 In-house 207-311 (311) Show / Hide
Range on Protein: 394-503
Range on HMM: 207-311/311
Sequence Identity: 26% (29 aa)

LNLSRAIGDHFyKRnkNLPPEEQMISALPDIKVLTLTDDHE-FMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRllSSIVEELLDQCLApDTSGDG
|...|..|| .     |   .| ..|  ||.|| ||. ..| |...| ||.|||......|...... ...  ..|    .|... |...|   ..    
LavaRslGDlW-sy--naksgeyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqs--rsvakalvkealq-rwrskk

TGCDNMTCIII
 .||.. |.. 
lraDnvsvivv

Phosphatase PPM1G.AA Subfamily.PPM1D.PD 31-106 33 1e-11 34.7 In-house 14-97 (311) Show / Hide
Range on Protein: 31-106
Range on HMM: 14-97/311
Sequence Identity: 33% (28 aa)

AMQGWRVSMEDAHNCIPE-----LDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYK---EGKLQKALEDAFLAIDAKLT
| || |  |||      |      . |.|...|.|||||.| | .  . |   ||.|| .    . ....|...||||.  .. 
adqGgrkymeDvvaivlereesaeeaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamk

Phosphatase PPM1G.AA Subfamily.PPM1H.PD 320-372 40 1.8e-11 33.6 In-house 157-209 (402) Show / Hide
Range on Protein: 320-372
Range on HMM: 157-209/402
Sequence Identity: 40% (21 aa)

KEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEV
.|.     | ||.|||.  ..| |||||||| .... ..  ..| |. || | 
reayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadftPeteR

Phosphatase PPM1G.AA Subfamily.ILKAP.PD 28-105 27 1.2e-10 31.3 In-house 12-104 (298) Show / Hide
Range on Protein: 28-105
Range on HMM: 12-104/298
Sequence Identity: 27% (25 aa)

GFSAMQGWRVSMEDAHNCIPELDS----------ETAMFSVYDGHGGEEVALYCAKYLPDIIK-----DQKAYKEGKLQKALEDAFLAIDAKL
.|.  .| |  |||||  . .||.          . . ..|.|||.|.. . ..|. | . |.     .. . |. ...|.| ||| . |.. 
afaerkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeef

Phosphatase PPM1G.AA Subfamily.LRR-PP2C.PD 28-107 27 2.8e-10 30.1 In-house 13-94 (257) Show / Hide
Range on Protein: 28-107
Range on HMM: 13-94/257
Sequence Identity: 27% (22 aa)

GFSAMQGWRVSMEDAHNCIPELD--SETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTT
||| | | | .|||      .    |.  .....|||||.. | .... |. |...    .. . .|.|..|. .|. ... 
gfsdmiGrrptmedelviyGsfrdksdedyyalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqise

Phosphatase PPM1G.AA Subfamily.PPM1L.PD 31-119 32 6.8e-10 28.9 In-house 18-114 (273) Show / Hide
Range on Protein: 31-119
Range on HMM: 18-114/273
Sequence Identity: 32% (32 aa)

AMQGWRVSMEDAHNCIPELDSET--AMFSVYDGHGGEEVALYCAKYLPDIIKDQK----AYKEGKL----QKALEDAFLAIDAKLTTEevIKELAQIAG
...| |  |||  .   ... .|   .|.|.||||||  | .. . |.. ||..     | || ..    .| |.|  |..| || ..  .|   .|||
svlGrrprmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllek--akraediaG

Phosphatase PPM1G.AA Subfamily.PPM1H.PD 389-470 26 5e-09 25.6 In-house 278-363 (402) Show / Hide
Range on Protein: 389-470
Range on HMM: 278-363/402
Sequence Identity: 26% (23 aa)

RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDD----HEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELR
|. . .  .| .|||  |  ..      ..|. |...|| ||.      . ...| ||.|.|.| .||   ... .|. |.. . |
RllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvdsedkkr

Sequence
Name Sequence Type Origin Length Description Download
PPM1G.AA Protein None 546 None Fasta, JSON
PPM1G.NA RNA None 1638 None Fasta, JSON
PPM1G.AA.PD_15-503 Protein Phosphatase Domain None 489 None Fasta, JSON