Gene PPM1G
PPM1G
Species: Human
Alias: PPM1G, PP2CGAMMA, PPP2CG, MGC2870, MGC1675, PP2CG
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPM1G.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPM1G.AA | PP2Cc | 15-503 | 19 | 4.5e-106 | 359.61 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 15-503
Range on HMM: 1-338/338
Sequence Identity: 19% (111 aa)
GDGVGAPRLPLPYGF--SAMQGWRVSMEDAHNCIPELDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEG------------------------
. .| . . ||. |.|||||..||||| |.| .| |.||||| |.| ||.| |..... .. ...
HS-MGYNSG-WRYGYMESSMQGWRHPMEDAHVCRP-------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHDKW
--KLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGL
.. .||..|||..| ..
FEDWEDALRKAFLRMDEEI---------------------------------------------------------------------------------
NGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSS
----------------------------------------------------------------------------------------------------
EEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGK----------ALDMSYDHKPEDEVELAR
.|||||||||..|.|||.||||.|.. .|. |.....||||..|.|..|
------------------------------------------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRR
IKNAGGK-------VTMDG-----RVNGG---LNLSRAIGDHFYKRNK----------------NLPPEEQMISALPDIKVLTL------TDDHEFMVIA
|..|||. . |.. |||| |..|||.|||.||. | .||..|....|.||... .| |.|..|....
IEQAGGRVMPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKW-KEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILC
CDGIWNVMSSQEVVDFIQSKISQRDENGEL------------------RLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIII
|||.|.|||.|||||.... ...... .. .... ..| |... |||||.|..
CDGLWDVMSNQEVVDIVRKCLRKWHHK-PVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----------CDNMTVIVV
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| Phosphatase | PPM1G.AA | Subfamily.PPM1G.PD | 19-505 | 59 | 2e-223 | 733.0 | In-house | 4-482 (482) | Show / Hide |
Range on Protein: 19-505 Range on HMM: 4-482/482 Sequence Identity: 59% (288 aa) GAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIA .... |.||.||||||||||||||||| .||..|..|.|||||||.||| ||||.|||..|..||||||...||||.|||..|.||.|||..|||..|| desneelsygasamqGWRvsmeDahncildldedtslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkkllteeilkelkeia GRPTEDEDEKEkvadedDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNS |...|...||| |...|||. |.|||....||||..|.....| ....||..|..|. |. .. || .|.|.||....|. ..|.....|... geekeegeeke------deeeeeaerlteeaelpleellekykelkkkkdldlksadgseesevsaaaakeaaseesereedneeeeeegkdseeksken ERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGME |. ||.....|... . |......||..|| ..||.|.|||.|.|||||.||||||....|||...||||||.|||||..||.|||.|||.|........ elktenaelkeeeeeeeeeeeeeesakeklvseakkklfeddeeesdeadeeeedskdskeeeeeesseeaedeedededeeeeedeeeededelaedll GK-EEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQM || ||||.||||||||||..||.||||||||||||.|..|||||.|.||||||||||.||..||||||.|||||||||||||.|||.||.|..||.|||| gkseepGkdsGttavvaLvkgkklivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvtldgRvnGGLnlsRalGDhaYktneeLpaeeqm ISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENgelRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICF ||||||||.|.||...||.|.|||||||||||||||||...|.....|. . ||.|.|||||.|||||||||||||||||..|. . isalPDikklilteedeFlvlacDGiWnvmssqevvdFvraklkesees---kklseiceeLlDaCLapdtsgDGtGCDnmtvvivql |
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| Phosphatase | PPM1G.AA | Group.PPM.PD | 21-533 | 46 | 1.1e-111 | 363.8 | In-house | 34-349 (459) | Show / Hide |
Range on Protein: 21-533
Range on HMM: 34-349/459
Sequence Identity: 46% (149 aa)
PRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAklttEEvikelaqiagr
. .| ||...||||| .|||.|... ..|.....|.|.|||||.|.| ..|| ||.|.| |. .|. ...|. ..|.|. | ..|. .. .|.|.
sgnglrygvasmqgwrkemEDrhvivenfdnndsffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldndd----rg-----------
ptededekekvadeddvdneeaallheeatmtieelltrygqnchkgpphsksgggtgeepgsqglngeagpedstretpsqengptakaytgfssnser
|. || |.||.|.||||.|||||||||||.||.|.||||||||.|....||| ..|.|||||.. | ||..|||.|..||||||.|..|||.||| .|.
----------------------------------------------------------------------------------------------------
gteagqvgepgiptgeagpscssasDKLPRVAKSKFFEDSEDESDEAEEEEedseecseeedgysseeaeneededdteeaeeddeeeeeemmvpgmegk
||||.|| ||..|..||...||.|.|.||.|.|.|..|||.|........... . |..| |.|.|..||. .| ||||.|||.|.|..... .
-------------------------ekvkkalrsafleldedlseeaneke-------------------------------------------------
eEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRnknlppEEQMISA
|. .....||| |.. ||.
-epgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidgRvnGilavsRalGdhdlkk------eeqmvsa
LPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENgELRLLSSIVEELLDQCLAP-DTsGDGTGCDNMTCIIICFKPRNTAELQPESGK
ePdvsvvklteedeflvlAsDGlWdvlsneevvefvretlekkkke-lkkdleeiaerlvdealakgst-gdgtscDNiTvivvtlndamrrqleivkke
RKLEEVLSTEGAEE
evleeelafmvael
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| Phosphatase | PPM1G.AA | Family.PPM.PD | 22-529 | 42 | 3.3e-98 | 319.3 | In-house | 12-310 (495) | Show / Hide |
Range on Protein: 22-529
Range on HMM: 12-310/495
Sequence Identity: 42% (128 aa)
RLPLPYGFSAMQGWRVSMEDAHNCIPELDS--ETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEgklqkaledaF----------Laidaklttee
. .| ||...||||| .|||||... .|.. ....|.|.|||||.|.| ..|| |..|.|.|. .|..|. .. ...|.|. |. |.|..|...|.|||
snglrygvasmqgwrsemeDahvvvenlennedfslfgvfDGhgGaeaaefaakklhkilkkqlekkd----------deksstsaessa----------
vikelaqiagrptededekekvadeddvdneeaallheeatmtieelltrygqnchkgpphsksgggtgeepgsqglngeagpedstretpsqengptak
|||||.|||||.|.||||||||.|....||| ..|.|||||.. | ||..|||||.. ||||||.|..|||.||...|. |||. .|| |||..
----------------------------------------------------------------------------------------------------
aytgfssnsergteagqvgepgiptgeagpscssasDKLPRVAKSKFFEDSEDESDEAEEEEedseecseeedgysseeaeneededdteeaeeddeeee
..|| ...||.|.|.||.|.|.|..|||....... . . |..| |||.|..||.... ||.|....... . . |..|..
------------------------------------ekvkealrkafleldeelseelneks--------------------------------------
eemmvpgmegkeePGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM-DGRVNGGLNLSRAIGDHFYKRn
.||
-------------agkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvirdgrvnGvlavsRalGdfdlkk-
knlppEEQM-ISALPDIKVLTLT-DDHEFMVIACDGIWNVMSSQEVVDFIQSKIsqrdeNGELRLLSSIVEELLDQCLAPDTSgdgtgcDNMTCIIICFK
-----eeqaivsaePditsvkltqeedeflvlasdGlWdvlsneevvelvretl-----eekeedleeiaeeLvdealakgsr------DNiTvlvvaly
PRNTAELQPESGKRKLEEVLSTE
enikqqnrfvlnknslmtrrstf
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| Phosphatase | PPM1G.AA | Subfamily.PPM1G2.PD | 324-503 | 50 | 1.5e-68 | 221.0 | In-house | 103-275 (275) | Show / Hide |
Range on Protein: 324-503 Range on HMM: 103-275/275 Sequence Identity: 50% (90 aa) GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDgRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPD ...|.||||.||. ..|.||||||||.|.|..|.. .|.||||..| | ||..||| | .. |||| | ||||.||. .|.|....||||.. |.||. desaGstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeesekkriiaagGfveln-rvngnLalsralgDfefkknvkkkpeeqivtavPD IKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDEngelrlLSSIVEELLDQCLAPDTSGDGTGCDNMTCIII | |..|.||.|.||||||.|....||||......... . |..|.|||||.|||||.| | ||||||..|. vlvkkldeddeflvLaCDGiWDvltnkevvdlvrerlvsgak------ldeiieelldkclapdssntgvGcDnmtvviv |
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| Phosphatase | PPM1G.AA | PP2C | 325-492 | 41 | 2.6e-67 | 234.75 | Pfam | 112-284 (284) | Show / Hide |
Range on Protein: 325-492 Range on HMM: 112-284/284 Sequence Identity: 41% (74 aa) SDSGTTAVVALIRGKQ--LIVANAGDSRCVVSEAGKAL----DMSYDHKPEDEVELARIKNAGGKVTM--DGRVNGG-LNLSRAIGDHFYKRNKNLPPEE ..||.|||.|.||... |.|||.||||.|.. .|.| ..|||||..| | .||..||| | .|||| |..|||.||..|| |....|.| WHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWWGFWRVNGVWLAVSRAFGDFHYKPNHTCFPKE QMISALPDIK-VLTLTDD-HEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDG |...| ||| . ..|.| .||...||||.|.|||.|||.|.... .|. . .. . |.|.| |.|. .. .. QPVTAEPDITPEHKITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWN------DPMEACEKLVDYCIAYGSEDNI |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1A.PD | 318-512 | 40 | 2.1e-61 | 197.9 | In-house | 104-287 (309) | Show / Hide |
Range on Protein: 318-512 Range on HMM: 104-287/309 Sequence Identity: 40% (79 aa) EGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMdGRVNGGLNLSRAIGDHFYKRNKNLPPEEQM ... ||.||||.|.. |.|..||.|||| |.|..||. ...|||| |. | ||.||||.|.. .|||| | .|||.||..||........||..| velskgedksGsTavvvlvspkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmi-kRvnGsLAvsRalGDydykekpekkateql ISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDEngelrlLSSIVEELLDQCLAPDTSgdgtgcDNMTCIIICF--KPRNTAE . |...|.. ....||.|.|||||| |||..||..|..|... |. |.....||||.|| .. |||..|.... |. . | vspepevtvierdeedeflvlacDGiwDvmsneevaefvksrlevtdd------leevanelldtcLekgsr------DNmsvilvllpgapkvsee |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1E.PD | 288-476 | 32 | 5.7e-38 | 120.8 | In-house | 73-250 (269) | Show / Hide |
Range on Protein: 288-476 Range on HMM: 73-250/269 Sequence Identity: 32% (62 aa) EAENEEDEDDTEEAEEDDEEEEEEMMVPGMegkEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMD ....|....|..|| .. .. .|... |. . ||.||||.||...|| || |||. .. . |.|. . ||||.| | .||..||| | . lvrqeklkedpaealkeafkltDerflqka---ereklksGstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvi G--RVNGGLNLSRAIGDHFYKrnknlppeeQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENgELRLLSSIV | |||| |..|||||| .| ...|. .|. ..|.........||||.|.|. .|||. ... ... |.. .. ..| gawRvnGvLsvsRaiGDvklk---------pyvsgeadvaeveldgsedylilacDGlwDvvneeevvklveefladgaed-lsevakllv |
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| Phosphatase | PPM1G.AA | Subfamily.ILKAP.PD | 320-502 | 35 | 1.2e-33 | 106.8 | In-house | 110-297 (298) | Show / Hide |
Range on Protein: 320-502
Range on HMM: 110-297/298
Sequence Identity: 35% (69 aa)
KEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVS---EAGK--------ALDMSYDHKPEDEVELARIKNAGGKVTmDGRVNGGLNLSRAIGDHFYKRN
|..| .|.||||.|. . | ||| |||. |. |.|. .. .|.||.| .. | ||..||| |. ||||.| |. ||.||| .|.
kakPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvr-dgRvlGvlevsRsiGDgrfkel
KnlppeeqmISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRD-ENGELRLLSSIVE---ELLDQCLAPDTSGDGTGcDNMTCII
... ||.| ..||.. |.|.||||.|.|.. .|||.||.. . ..| .. . . | | |. . ||.. |.. ||.| ..
g--------vistPdvkkceLtenDlfvvlaCDGLwkvfeadevvkfilkvlededdrkikqeegksaeevrfevacerlAseavkrgss-Dnvtvll
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| Phosphatase | PPM1G.AA | Subfamily.PPM1L.PD | 326-462 | 45 | 7e-33 | 104.3 | In-house | 112-245 (273) | Show / Hide |
Range on Protein: 326-462 Range on HMM: 112-245/273 Sequence Identity: 45% (61 aa) DSGTTAVVALIRGKQLIVANAGDSRCVVS-EAGKALDMSYDHKPEDEVELARIKNAGGKVTMDG--RVNGGLNLSRAIGDHFYKrNKNlppeeqMISALP .||||..||.....||||| |||| |. . |||. .|.||||.. | |||.||| ....| ||.| | .|||.||. | .||.. | ||| . | iaGttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafrGvwrvaGvlatsralGdyplk-dkn------lviadp DIKVLTLTDD-HEFMVIACDGIWNVMSSQEVVDFIQSKISQ | ||...|.||.|. .| .| | ||. .... diltfdlddhkpeflilasdGlwdtfsneeavrfikerlke |
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| Phosphatase | PPM1G.AA | Subfamily.LRR-PP2C.PD | 325-464 | 39 | 1.6e-32 | 102.9 | In-house | 97-231 (257) | Show / Hide |
Range on Protein: 325-464 Range on HMM: 97-231/257 Sequence Identity: 39% (54 aa) SDSGTTAVVALIRGKQLIVANAGDSRCVVS-EAGKALDMSYDHKPEDEVELARIKNAGGKVTMD---GRVNGGLNLSRAIGDHFYKrnknlpPeeqMISA ||||...|| ... ..|| |||| |.. | | .|.|||| .| | ||...||.| . |||| | .|||.|| | .| . . ||.. |. kfiGttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvstvvtsrvnGtlavsralGdsfle------P---fvvp LPDIK-VLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSkISQRD . ...|...||||||...| .| |. . . ||. . dPdlsqsleiskkdkflilacdGiwdlisdeeaveivag-isdpe |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1K.PD | 325-458 | 40 | 2e-27 | 86.2 | In-house | 102-233 (264) | Show / Hide |
Range on Protein: 325-458 Range on HMM: 102-233/264 Sequence Identity: 40% (52 aa) SDSGTTAVVALIR-GKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMD----GRVNGGLNLSRAIGDHFYKRNKnlppeeqmIS .||||| |.|.| |..|..|. |||| .. ||| .. ||.|| . | |||.|||.|... .||. | ..|..|| ||. | |. | | . lssGttatvsllrdGnelvlaslGdsrailcrnGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkryG--------vi ALPDIKVLTL-TDDHEFMVIACDGIWNVMSSQEVVDFIQS .. |.|. ||| .|..|||. |... atPetkslkvkhaadsflvlitdgisfvvnsqelcdlvrl |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1G2.PD | 27-113 | 46 | 2.3e-27 | 86.0 | In-house | 12-103 (275) | Show / Hide |
Range on Protein: 27-113 Range on HMM: 12-103/275 Sequence Identity: 46% (42 aa) YGFSAMQGWRVSMEDAHNCIPEL-----DSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKE | |.|||.|..||||| .|| |...|.|.|.|||||..|| |..| | .|. .|..|||.|...|.||||..| .|. .| .|. vgvssmqGyrlnmeDahilenelleksddkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdeklkd |
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| Phosphatase | PPM1G.AA | Subfamily.PDP.PD | 326-468 | 30 | 1.2e-23 | 74.3 | In-house | 164-334 (409) | Show / Hide |
Range on Protein: 326-468
Range on HMM: 164-334/409
Sequence Identity: 30% (51 aa)
DSGTTAVVALIRGKQLIVANAGDSRCVVS---EAG--KALDMSYDHKPEDEVELARIKNAGG-----KVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEE
||..|..|||.|..| |||.||.|.|. | | .| .| |. . | |. |||.. | ..||. | | .|| || || .|.| .
lsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRikkeHPgeesktvirngRlLgeLaPlRAFGdvryKwskelqkkv
-------Q-----------MISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGE
. ..| |.. |. . |.|.| ||.|...|..|||. .. ....... .
lekllevkvvepkdyktPPYltaePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkknkak
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| Phosphatase | PPM1G.AA | Subfamily.PPM1A.PD | 25-112 | 38 | 1.8e-23 | 73.3 | In-house | 10-107 (309) | Show / Hide |
Range on Protein: 25-112 Range on HMM: 10-107/309 Sequence Identity: 38% (37 aa) LPYGFSAMQGWRVSMEDAHNCIPELDS---ETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAY-------KEGKLQKALEDAFLAIDAKLTTEEVIK | || |.||||||.||||| .. .| | . . |.|.|||.|..|. |||| | ..| ..... .. |...||...||..| |... .. lryglssmqgwRvemEDahtavidlpsklkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekirklvels |
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| Phosphatase | PPM1G.AA | PP2C | 25-102 | 39 | 2e-19 | 71.51 | Pfam | 1-93 (284) | Show / Hide |
Range on Protein: 25-102 Range on HMM: 1-93/284 Sequence Identity: 39% (37 aa) LPYGFSAMQGWRVSMEDAHNCIP------ELDSETAMFSVYDGHGGEEVALYCAKYLP----DIIKDQKAYKEG---KLQKALEDAFLA--ID . |||..||||| .||||| |.| . ... . | |.||||| ..| ||.| |. .|.| .| ..|| ....|| ..||. .| WDYGFCRMQGWRHFMEDAHHCYPNMNCSSSGKDSWHFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTD |
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| Phosphatase | PPM1G.AA | Subfamily.TAB1.PD | 326-454 | 34 | 6.1e-16 | 48.4 | In-house | 136-274 (336) | Show / Hide |
Range on Protein: 326-454 Range on HMM: 136-274/336 Sequence Identity: 34% (48 aa) DSGTTAVVALIRGKQLIVANAGDSRCVVSEAG----KALDMSYDHKPEDEVELARIKNAG---GKVTMDGRVnGGLNLSRAIGDH----FYKRNKNLPP- ||||||||| ..| ||| |||| .. | |. .| || . | || |.|. | ... .|. |. . |.|||. ||.. | ... sgGttavvalilnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLGldieqikqnkrl-gskeaTRsiGdykikkgykevdvlssA EEQMISALPDIKVLTLTDDHE-FMVIACDGIWNVMssQEVVD | | |||. .| | |... ||. . . |. . kgePiiatPdingpkdindlegfllLmSdGlykal--ieltn |
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| Phosphatase | PPM1G.AA | Subfamily.PHLPP.PD | 340-457 | 28 | 3.4e-15 | 46.0 | In-house | 118-227 (257) | Show / Hide |
Range on Protein: 340-457 Range on HMM: 118-227/257 Sequence Identity: 28% (34 aa) QLIVANAGDSRCVVSEAGKALDMSYDHKPEDE-VELARIKNAGGKVTMDGRVNGGLNLSRAIGdHFYKRNKNLPPeeqmisalPDIKVLTLTDDHEFMVI | .||.|. . |. || | .| . | . || |||.| . .| |..||| .. .| .| ... || | .. ..||.. |.... tltaanvgkcklvlirnGkplplskvyileiddeelkrikeakaiitednkvnGviestrilG-ytflfPvvlPk--------phvrsvlLteqdEllil ACDGIWNVMSSQEVVDFIQ ...|.|.| .|.|. .. GnkalWevlsideaveavr |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1D.PD | 324-387 | 39 | 1.5e-13 | 40.8 | In-house | 111-180 (311) | Show / Hide |
Range on Protein: 324-387 Range on HMM: 111-180/311 Sequence Identity: 39% (27 aa) GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGK------ALDMSYDHKPEDEVELARIKNAGGKVTMD | .|||| | .||...| ||. |||. |.. . | . |||||. | ||...||.|.. lstaGttasvviirreklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaak |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1K.PD | 28-107 | 34 | 2e-13 | 40.3 | In-house | 13-90 (264) | Show / Hide |
Range on Protein: 28-107 Range on HMM: 13-90/264 Sequence Identity: 34% (27 aa) GFSAMQGWRVSMEDAHnCIPELDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKaYKEGKLQKALEDAFLAIDAKLTT |. ...| | || .. ||| . |.|.||||| | .. . | |... . || |.. | .||. .| ||. GkdsliGkraenedrf-klkeldpdllyfavfdGhgGssaadfvhdkleeivrrll-ekekdleevlkqafeeldkklkr |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1E.PD | 30-108 | 34 | 6e-13 | 38.7 | In-house | 16-101 (269) | Show / Hide |
Range on Protein: 30-108 Range on HMM: 16-101/269 Sequence Identity: 34% (29 aa) SAMQGWRVSMEDAHNCIPEL----D----SETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLqKALEDAFLAIDAKLTTE |... | ||| | ....| . .| |.|.|.||||| | | | |. |. . .|. || . .||..|| ..| .... aavknkrrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpa-ealkeafkltDerflqk |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1D.PD | 394-503 | 26 | 7.9e-13 | 38.4 | In-house | 207-311 (311) | Show / Hide |
Range on Protein: 394-503 Range on HMM: 207-311/311 Sequence Identity: 26% (29 aa) LNLSRAIGDHFyKRnkNLPPEEQMISALPDIKVLTLTDDHE-FMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRllSSIVEELLDQCLApDTSGDG |...|..|| . | .| ..| ||.|| ||. ..| |...| ||.|||......|...... ... ..| .|... |...| .. LavaRslGDlW-sy--naksgeyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelkeeqs--rsvakalvkealq-rwrskk TGCDNMTCIII .||.. |.. lraDnvsvivv |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1D.PD | 31-106 | 33 | 1e-11 | 34.7 | In-house | 14-97 (311) | Show / Hide |
Range on Protein: 31-106 Range on HMM: 14-97/311 Sequence Identity: 33% (28 aa) AMQGWRVSMEDAHNCIPE-----LDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYK---EGKLQKALEDAFLAIDAKLT | || | ||| | . |.|...|.|||||.| | . . | ||.|| . . ....|...||||. .. adqGgrkymeDvvaivlereesaeeaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamk |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1H.PD | 320-372 | 40 | 1.8e-11 | 33.6 | In-house | 157-209 (402) | Show / Hide |
Range on Protein: 320-372 Range on HMM: 157-209/402 Sequence Identity: 40% (21 aa) KEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEV .|. | ||.|||. ..| |||||||| .... .. ..| |. || | reayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadftPeteR |
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| Phosphatase | PPM1G.AA | Subfamily.ILKAP.PD | 28-105 | 27 | 1.2e-10 | 31.3 | In-house | 12-104 (298) | Show / Hide |
Range on Protein: 28-105 Range on HMM: 12-104/298 Sequence Identity: 27% (25 aa) GFSAMQGWRVSMEDAHNCIPELDS----------ETAMFSVYDGHGGEEVALYCAKYLPDIIK-----DQKAYKEGKLQKALEDAFLAIDAKL .|. .| | ||||| . .||. . . ..|.|||.|.. . ..|. | . |. .. . |. ...|.| ||| . |.. afaerkGereemeDahvilndldeqtrkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeef |
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| Phosphatase | PPM1G.AA | Subfamily.LRR-PP2C.PD | 28-107 | 27 | 2.8e-10 | 30.1 | In-house | 13-94 (257) | Show / Hide |
Range on Protein: 28-107 Range on HMM: 13-94/257 Sequence Identity: 27% (22 aa) GFSAMQGWRVSMEDAHNCIPELD--SETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTT ||| | | | .||| . |. .....|||||.. | .... |. |... .. . .|.|..|. .|. ... gfsdmiGrrptmedelviyGsfrdksdedyyalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqise |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1L.PD | 31-119 | 32 | 6.8e-10 | 28.9 | In-house | 18-114 (273) | Show / Hide |
Range on Protein: 31-119 Range on HMM: 18-114/273 Sequence Identity: 32% (32 aa) AMQGWRVSMEDAHNCIPELDSET--AMFSVYDGHGGEEVALYCAKYLPDIIKDQK----AYKEGKL----QKALEDAFLAIDAKLTTEevIKELAQIAG ...| | ||| . ... .| .|.|.|||||| | .. . |.. ||.. | || .. .| |.| |..| || .. .| .||| svlGrrprmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllek--akraediaG |
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| Phosphatase | PPM1G.AA | Subfamily.PPM1H.PD | 389-470 | 26 | 5e-09 | 25.6 | In-house | 278-363 (402) | Show / Hide |
Range on Protein: 389-470 Range on HMM: 278-363/402 Sequence Identity: 26% (23 aa) RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDD----HEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELR |. . . .| .||| | .. ..|. |...|| ||. . ...| ||.|.|.| .|| ... .|. |.. . | RllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvdsedkkr |
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