Gene PPM1H
PPM1H
Species: Human
Alias: FLJ13253, PPM1H, NERPP-2C, ARHCL1, URCC2, KIAA1157
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPM1H.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPM1H.AA | PP2Cc | 67-505 | 17 | 2.9e-39 | 137.7 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 67-505
Range on HMM: 1-338/338
Sequence Identity: 17% (88 aa)
ILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAVTSTPNRNSSKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLL
. |. ||.| . | ..|| .| . . .||||.|. .| ... |
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP---------------------------------------------FFGVFDGHGGHECAQYCRKHL
QHHITEQLQDIVDIL------KNSAVLPPTCLGEEPENTPANSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERER
.|. |.|| | . . . .| . . .. .... .. ||..||..|| .|
HEHLAEELQFHKDDDYKENDEMQ-D-EP----------------------------------EMW-W-R-MW-HDKWFEDWEDALRKAFLRMDEEI----
SSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGE----------IIPMSSEFTP--ETERQRLQYLAF--MQPHLLGNEFTHLEFPRRVQRKELGK
|||.... .||||||.|||||...|||. ..... . .| |.||.|.. . |
--------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGGRVM-------------------------
KMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMAT---IGVTRGLGDHDLKVHDSNIYIK------------------PFLSSAPEVRIYDLSK--
. . .. ... .|| . . |.| .|||..| ... | |.... |.| . .|.
------------------P-MHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKW-KED-E-KIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMT
--YDHGSDDVLILATDGLWDVLSNEEVAEAITQFL------PNCDP------------DDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVY
... || |||..||||||.||.|| . ....| |.... . . ||. |.. |. |...|
VPTPD--DDFLILCCDGLWDVMSNQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI-----------------CDNMTVI
VI
|.
VV
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| Phosphatase | PPM1H.AA | Subfamily.PPM1H.PD | 68-505 | 57 | 3.9e-202 | 661.5 | In-house | 2-402 (402) | Show / Hide |
Range on Protein: 68-505 Range on HMM: 2-402/402 Sequence Identity: 57% (254 aa) LKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAgAVTSTPnrnsskrrsslpnGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQ .|..|.||||.|||||||||||..|||||...||..|||. .|||.. ||. .|||.|..| ....|..|||||||||||.|||.||. pkdlrklPwaaGYaevinagkselneDqaaakvlllkkke-svtska-------------geeeelkekskeeklplayfglfDGhaGsgaalvaskllh HHITEQLQDIVDILKNSAVlPPTCLGEEPENTPAnsrtltraaslrggvgapgspsTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSSYNISG .|..|.|.|....|..... ....||||....|. .| ..|..||||..|.||||||||||.||| ||.|||..|.|.| khlkekledvlellleksa-eklalgeerkeapt----------------------epseifveekkiskeeLviGalesaflemDeqiarereayrikG GCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDED |||||....||||||||||||||||..|..||||.|..|||||||||||.|||..|.|||.|||.|||..|...|.||...||||.|||||||||.|.|| GCtalvalvllgklYvanaGDsRailvrkdeiiplsadftPeteRqRlqelaflkPeLlgkeftrlefqkRlkkkdlgqrvlyRdqnmtGWayktveeeD LKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRY ||||||.|||||||..||||||||||||.|||.|.|..||||||..||||..||..... .||||||||||||||||||||||.....|...|..|..|| lkfplisgegkkaRllatigvtRGlGDheLkvvdtnlsikPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvdsedkkry TLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVI | .||.||..|||.|||.|||..... .|.|||||.|| tavaqeLvaaarGklkdkgWrlkeekaasvDDisvfvi |
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| Phosphatase | PPM1H.AA | Group.PPM.PD | 77-508 | 27 | 8.2e-75 | 242.2 | In-house | 3-322 (459) | Show / Hide |
Range on Protein: 77-508 Range on HMM: 3-322/459 Sequence Identity: 27% (113 aa) ATGYAEVINAGKSTHNEDQASCEVLTvKKKAGAVTSTPNRNSSKRRSSLPNGEGLQLKENSESEGvscHYWSLFDGHAGSGAAVVASRLLQHHITEQLQD ||||.|||||. .|||||| | ...|| . . .| ... .. . || .... .....||||.|. || .|.. | .....||.. yvgyaeainagktvqnedqasaehhl-essagsgnglrygvasmqgwrkemEDrhvivenfdnnd---sffgVfDGHgGaeaaefaakkLpkilkkqlkk IVDILKNSAVLPPTCLGEepenTPansrtltraaslrggvgapgspstpptrfftekkipheCLVIGALESAFKEMDLQIERERSSYN---ISGGCTALI | .... .. . . | .||.|||.|.| ....|..... ...|.||.... kkdevskksaeasldndd----rg--------------------------------------ekvkkalrsafleldedlseeanekeepgkdsGtTAvv VICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPE--TERQRLQYLAfmqphllgnefthlefprrvqrkelgkkmlyrdfnmtGWayktiededlkfP . .||||||||||||.. |||...|.| ...|| .||.|.. .. |.||. ...|.|.|||| alingkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekag-------------------------------------Gs------------v ---LiygegkkaRVMATIGVTRGLGDHDLKVhdsniyIKPFLSSAPEVRIYDLSkydHGsDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYT ||| ....|. |.|. ..|. . |..|.||.||||||||||||.| . . |. .... .... .|..||..|.. | |. . .| eidg--------RvnGilavsRalGdhdlkk------eeqmvsaePdvsvvklt---ee-deflvlAsDGlWdvlsneevvefvretlekkkkelkkdle LAAQDLVMRARGVlkdrGwriSNDRLGSGDDISVYVIPLI |.|.| |. | eiaerlvdealak----g---stgdgtscDNiTvivvtln |
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| Phosphatase | PPM1H.AA | Family.PPM.PD | 72-509 | 22 | 3.5e-62 | 200.5 | In-house | 11-288 (495) | Show / Hide |
Range on Protein: 72-509
Range on HMM: 11-288/495
Sequence Identity: 22% (94 aa)
RRLPWATGYAEVInAGKSTHnEDQASCevltvkK------KagavtstpnrnsskrrsslpngeglqlkensesegvSCHYWSLFDGHAGSGAAVVASRL
. ....|.|. .|.. ||. .. . .......||||.|. || .|.. |
ssnglrygvasmq-gwrsem-eDahvv------venlenne------------------------------------dfslfgvfDGhgGaeaaefaakk
LQHHITEQLQDIVDILKNS-----AvlpptclgeepentpansrtltraaslrggvgapgspstpptrfftekkipheCLVIGALESAFKEMDLQIERER
.....||.. | .... | | ||..||.|.| ....|..
lhkilkkqlekkddeksstsaessa-----------------------------------------------------ekvkealrkafleldeelseel
SSYN--ISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPE--TERQRLQYLAfmqphllgnefthlefprrvqrkelgkkmlyrdfnmt
... ..|.||..|.. .||||||||||||...|||.....| ...|| .||.|.. ..|. ...||. .. |.|.||
neksagkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEreRIekag-------------------------------------
GWayktiededlK-FpliygegKKARVMATIGVTRGLGDHDLKVhdsN--IyikpFLSSAPEVRIYDLSkydHGSDDVLILATDGLWDVLSNEEVAEAIT
|.||| . . ..|. |... ..|. . .|..|.||.||||||||||||.| . . | .. .... .|..|| .| |..
Gk----------vvi-------rdgrvnGvlavsRalGdfdlkk---eeqa----ivsaePditsvklt---qeedeflvlasdGlWdvlsneevvelvr
QFLpncdPDDPHRYTLAAQDLVMRArgvLKDRgwrisndrlgSGDDISVYVIPLIH
|.|.|.| |. | .
etl----eekeedleeiaeeLvdea---lakg----------srDNiTvlvvalye
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| Phosphatase | PPM1H.AA | Subfamily.PPM1G2.PD | 138-313 | 35 | 2.3e-18 | 56.4 | In-house | 37-152 (275) | Show / Hide |
Range on Protein: 138-313 Range on HMM: 37-152/275 Sequence Identity: 35% (40 aa) ESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEqlqdivdilknsavlpptclgeepentpansrtltraaslrggvgapgspstpptrffteKKIPH .|. |. ....|||| |. .| |.. |.. |..|| .| . .|. ||.|.| .. .... . | |.||..|. ||||||||||||.. .| ksddkslalfavfDGhGGakvakyagkklikkiak------------------------------------------------------------kksfk ECLVIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQ .. .| . |..| egaleqilkdafletDeellkdeklkdesaGstavvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeese |
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| Phosphatase | PPM1H.AA | Subfamily.ILKAP.PD | 244-504 | 23 | 5.8e-18 | 55.3 | In-house | 92-297 (298) | Show / Hide |
Range on Protein: 244-504 Range on HMM: 92-297/298 Sequence Identity: 23% (54 aa) ALESAFKEMDLQIERER--SSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSeftpeteRQRLQYLAFMQPHLLGNEfthlefprrvqr .| |||. | .. .. . |.|| .|. . .||||| |||.|...|. | . . .. . . | ...|. . | clvdafkktDeeflklaskakPvWkdGstavvvlvvdnvlyvanlGDskavlaRakeegdkag-------estiasvlLskdHtpasy------------ kelgkkmlyrdfnmtgwayktieDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDsniyikpfLSSAPEVRIYDLSKYDHgsddVLILATDGLWD .. ||. ..| | .|| | . ..| |.|. .|..|. ..|| ||||.|....||.. |.. | . ... .|. .. -----------------------eerkriqkaGgvvrdgRvlGvlevsRsiGDgrfkelg--------vistPdvkkceLtenDl----fvvlaCDGLwk VLSNEEVAEAITQFLPNCdpddphRYTLAAQDLVMRARGV-LKDRGWRISND--RLGSGDDISVYV |. | .. |. .. . ||.|...| . vfeadevvkfilkvlede------ddrkikqeegksaeevrfevacerlAseavkrgssDnvtvll |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1D.PD | 145-456 | 23 | 2.1e-16 | 50.1 | In-house | 42-271 (311) | Show / Hide |
Range on Protein: 145-456
Range on HMM: 42-271/311
Sequence Identity: 23% (59 aa)
HYWSLFDGHAGSGAAVVASRLLQHHITEQLQDiVDILKNSavlpptclgeepentpansrtltraaslrggvgapgspstpptrfftekkipheclVIGA
. ..|||| | || |.. | . |..| . . ...|. |...|| .. ......... | || .||. |||||. |||....
afvavfDGHGGkeAakfarehlwsvikkqkkf-lsseped--------------------------------------------------------vleA
LESAFKEMDLQIERERSSY-------NISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEiipmsseftpetERQRLQYLAFMQPHLLgnefTHLEFPR
. . . ..|... | ..| .|.. || |. . . . | . .| .. .. . . |.| |||
ireaflatheamkkklaeWpktksgllstaGttasvviirreklyvahvGDsgivlgvkep------------kekklrakeltkdHkP----espeEke
RVQrkEL-GKKMLYRDFNMTGWAYKTIEDEDLkfpliygegKKARVMATIGVTRGLGDHDLKVHDSNIYIkpfLSSAPEVRIYDLskyDHGSDDVLILAT
. |. |.| |.| . | | .....|||.||||.||. |.. . ...
rie--elGGevaaksGvkRvvWkRprlehngp---------tvideiPFLavaRslGDlWsynaksgeyv---vsPePdvkvrtl---dpneekfiilas
DGLWDVLSNEEVAEAITQFL
DGlwnvltpedavsvvekee
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| Phosphatase | PPM1H.AA | Subfamily.PPM1A.PD | 379-456 | 38 | 1.2e-15 | 47.6 | In-house | 172-245 (309) | Show / Hide |
Range on Protein: 379-456 Range on HMM: 172-245/309 Sequence Identity: 38% (30 aa) KARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKydhgSDDVLILATDGLWDVLSNEEVAEAITQFL . || .. |.| |||.| | ... . .|. |||.. . .. .|. |.||.||.|||.||||||| ... | ikRvnGsLAvsRalGDydykekpekkateqlvspepevtvierde----edeflvlacDGiwDvmsneevaefvksrl |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1L.PD | 136-314 | 27 | 3.2e-15 | 46.4 | In-house | 34-161 (273) | Show / Hide |
Range on Protein: 136-314 Range on HMM: 34-161/273 Sequence Identity: 27% (36 aa) NSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAVlpptclgeepentpansrtltraaslrggvgapgspstpptrfftekkI . ...... .. ..|||| | || | .| . | ..|... .|.| .. |. . |. ... .|. .....|. |.|||| . .| ||| ediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvp------------------------------------------------i PHECLVIGALESAFKEMdlqIERERSSYNISgGCTALIVICLLGKLYVANAGDSRAIII-RNGEIIPMSSEFTPETERQR |||| ... ..|. ||.| . |. ..| nfsklltdeilsvdekl---lekakraedia-GttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvker |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1G.PD | 266-312 | 45 | 8.7e-12 | 35.0 | In-house | 306-352 (482) | Show / Hide |
Range on Protein: 266-312 Range on HMM: 306-352/482 Sequence Identity: 45% (20 aa) SGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETER |.||.. . ||.||||||||... |||. . .| . || | dsGttavvaLvkgkklivanaGDsRcvlsrnGkaldlsiDhkPeDev |
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| Phosphatase | PPM1H.AA | Subfamily.PDP.PD | 403-460 | 39 | 1.2e-11 | 34.6 | In-house | 277-330 (409) | Show / Hide |
Range on Protein: 403-460 Range on HMM: 277-330/409 Sequence Identity: 39% (23 aa) NIYIKPFLSSAPEVRIYDLSKydhgSDDVLILATDGLWDVLSNEEVAEAITQFLPNCD . . |.|.. ||| . |.. .| |.||||||||.||||||.. ....| . . dyktPPYltaePevtshklre----ndkFLvlatDGLwdllsneevvslVgehlakkk |
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| Phosphatase | PPM1H.AA | PP2C | 150-303 | 19 | 1.3e-11 | 43.33 | Pfam | 41-156 (284) | Show / Hide |
Range on Protein: 150-303 Range on HMM: 41-156/284 Sequence Identity: 19% (34 aa) FDGHAGSGAAVVASRLLQ----HHITEQLQDIVD-ILKNSAVLPPTCLGEEPENTPANSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGA ||||.|. || ... | .. |. .. . . .| | FDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNP----------------------------------------------------------KDVEQA LESAFKEMDLQIERER---SSYN------ISGGCTALIVICLLGK--LYVANAGDSRAIIIRNGEII----PMS | ..| | | .. . .. | ...||||.... | |||||.|||||...|||... ... LRKSFLECDTDMMFYSAPWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLT |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1E.PD | 240-314 | 32 | 1.6e-11 | 34.0 | In-house | 84-156 (269) | Show / Hide |
Range on Protein: 240-314 Range on HMM: 84-156/269 Sequence Identity: 32% (24 aa) LviGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQR . ||..|||..| .. . .. .. .|.|| .|. .|||| |||.|...|.||.. . . || |. . a--ealkeafkltDerflqkaereklksGstavvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEk |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1A.PD | 242-314 | 34 | 3.8e-11 | 32.9 | In-house | 86-162 (309) | Show / Hide |
Range on Protein: 242-314 Range on HMM: 86-162/309 Sequence Identity: 34% (26 aa) IGALESAFKEMDLQIERERSSYNI--SGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPE--TERQR ||...| |.| .|... . . |.|| |. |||.||.|||||...|||. . .... | .|..| kealrkgfLelDekirklvelskgedksGsTavvvlvspkklylancGDsRavlsrngkvvfateDHkpsdpkEkeR |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1E.PD | 380-459 | 38 | 1.2e-10 | 31.2 | In-house | 172-238 (269) | Show / Hide |
Range on Protein: 380-459 Range on HMM: 172-238/269 Sequence Identity: 38% (30 aa) ARVMATIGVTRGLGDHDLkvhdsniyiKPFLSSAPEVRIYDLSkydhGSDDVLILATDGLWDVLSNEEVAEAITQFLPNC || .. |.| .|| .| ||..|. ..| ..| ||.|.||||.||||||. .||| .....|| . wRvnGvLsvsRaiGDvkl---------kpyvsgeadvaeveld----gsedylilacDGlwDvvneeevvklveefladg |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1L.PD | 381-456 | 38 | 3.2e-10 | 30.0 | In-house | 178-243 (273) | Show / Hide |
Range on Protein: 381-456 Range on HMM: 178-243/273 Sequence Identity: 38% (29 aa) RVMATIGVTRGLGDHDLKvhDSNIYIkpflsSAPEVRIYDLSKYDhgsDDVLILATDGLWDVLSNEEVAEAITQFL || . ..| |||. || | |. | . |.. .|| ... . ||||.||||| .|||| . | . | rvaGvlatsralGdyplk--dknlvi-----adpdiltfdlddhk---peflilasdGlwdtfsneeavrfikerl |
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| Phosphatase | PPM1H.AA | Subfamily.TAB1.PD | 251-297 | 44 | 6.9e-10 | 28.5 | In-house | 120-167 (336) | Show / Hide |
Range on Protein: 251-297 Range on HMM: 120-167/336 Sequence Identity: 44% (21 aa) EMDLQIERER-SSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNG . . .|.| . .|||| ||.... | |||||| ||||||.... kyeekinrlkeleseisgGttavvalilnnkLyvaNvGdsrAilvese |
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| Phosphatase | PPM1H.AA | Subfamily.LRR-PP2C.PD | 379-454 | 33 | 7.1e-10 | 28.8 | In-house | 163-226 (257) | Show / Hide |
Range on Protein: 379-454 Range on HMM: 163-226/257 Sequence Identity: 33% (25 aa) KARVMATIGVTRGLGDhdlkvhdsnIYIKPFLSSAPEVRIydlSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQ .|| |. |.| ||| ....||. . |.. | . .| |||| ||.||..|.|| | . . tsrvnGtlavsralGd---------sflePfvvpdPdlsq---sleiskkdkflilacdGiwdlisdeeaveivag |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1G2.PD | 379-454 | 31 | 7.7e-10 | 28.5 | In-house | 165-236 (275) | Show / Hide |
Range on Protein: 379-454 Range on HMM: 165-236/275 Sequence Identity: 31% (23 aa) KARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSkydhGSDDVLILATDGLWDVLSNEEVAEAITQ || .. . | |||. | ... |.| . .|. .|. |.|| ||.||||.|.|| . . . lnrvngnLalsralgDfefkknvkkkpeeqivtavPDvlvkkld----eddeflvLaCDGiWDvltnkevvdlvre |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1K.PD | 245-314 | 32 | 3.8e-09 | 26.2 | In-house | 77-154 (264) | Show / Hide |
Range on Protein: 245-314 Range on HMM: 77-154/264 Sequence Identity: 32% (25 aa) LESAFKEMDLQIERERSSY-----NISGGCTALIVICLLG-KLYVANAGDSRAIIIRNGEIIPMSSEFTPETE--RQR | ||.|.| ...| | | || ... | .| .|. ||||||. |||. .... .|| . ..| lkqafeeldkklkrylefsvaeaellssGttatvsllrdGnelvlaslGdsrailcrnGkakkltkdhdPerkeeker |
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| Phosphatase | PPM1H.AA | PP2C | 388-456 | 29 | 5.7e-09 | 33.79 | Pfam | 192-258 (284) | Show / Hide |
Range on Protein: 388-456 Range on HMM: 192-258/284 Sequence Identity: 29% (21 aa) VTRGLGDHDLKVHDSNIYIKPFLSSAPEVR-IYDLSKYDHGS-DDVLILATDGLWDVLSNEEVAEAITQFL |.| .||...| .. .. ...|.. .... . |. ||||.||||||.|..|| . . |.. VSRAFGDFHYKPNHTCFPKEQPVTAEPDITPEHKITP----DHDEFLILACDGLWDVMSDQEVCDIVRQCR |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1G.PD | 380-458 | 29 | 2.1e-08 | 23.9 | In-house | 368-442 (482) | Show / Hide |
Range on Protein: 380-458 Range on HMM: 368-442/482 Sequence Identity: 29% (23 aa) ARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKydhgSDDVLILATDGLWDVLSNEEVAEAITQFLPN || . . | |||| | . . .| |.... | . |. |.||.||.|.|.| .|| . ... | . gRvnGGLnlsRalGDhaYktneeLpaeeqmisalPDikklilte----edeFlvlacDGiWnvmssqevvdFvraklke |
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| Phosphatase | PPM1H.AA | Subfamily.PPTC7.PD | 423-484 | 29 | 4.5e-08 | 23.2 | In-house | 173-230 (263) | Show / Hide |
Range on Protein: 423-484 Range on HMM: 173-230/263 Sequence Identity: 29% (18 aa) KYDHGSDDVLILATDGLWDVLSNEEVAEAITqflpNCDPDDPHRYTLAAQDLVMRARGVLKD ... ..|...|||||..| ||..|. | .. . . |... |.|. |...|| . .| sfevkkgDlillatDGvfDNlsedeilevlk----elkerdeeelqllanslaekarelsld |
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| Phosphatase | PPM1H.AA | Subfamily.PDP.PD | 147-295 | 23 | 4.6e-08 | 22.9 | In-house | 40-193 (409) | Show / Hide |
Range on Protein: 147-295 Range on HMM: 40-193/409 Sequence Identity: 23% (38 aa) WSLFDGHAGSGAAVVASRLLQHHITEQL---QDIVDILKNSAVLPPTCLGEEPENTPaNSRTLTRAASLrggvgapgspSTPPTRFFTEKKIPH-ECLVI ..||||.| .| |. | .... .| |..... .. | . . |..| | .|.....| . . ........ | | fgvfDGHggaacaeavskrLlkyvaasllkkqvlleaeeaekslkellsilklekkp-ndsvlkeskkl----------ykeslkkyvqelleakelkve GALESAFKEMDLQIERERS-------S------YNISGGCtALIVICLLGKLYVANAGDSRAIIIR ||..||...| .| | . .|| | ||.. .|.|||.||.||.. . ealkkaFlrlDkdislealkkleekvleeavlkvalsGac-allaliegtelhvAntGDcravlgv |
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| Phosphatase | PPM1H.AA | Subfamily.LRR-PP2C.PD | 244-314 | 31 | 6.7e-08 | 22.3 | In-house | 80-147 (257) | Show / Hide |
Range on Protein: 244-314 Range on HMM: 80-147/257 Sequence Identity: 31% (23 aa) ALESAFKEMDLQIererSSYNISGGCTALIVICLLGKLYVANAGDSRAIII-RNGEIIPMSSEFTPETERQR .|. |.||...|| | . . |.|| |. . | |.|| ||||... ..| .| . | |... slkkaykeistqi----serpkfiGttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseesee |
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| Phosphatase | PPM1H.AA | Family.PPTC7.PD | 423-484 | 27 | 8e-08 | 22.4 | In-house | 172-229 (262) | Show / Hide |
Range on Protein: 423-484 Range on HMM: 172-229/262 Sequence Identity: 27% (17 aa) KYDHGSDDVLILATDGLWDVLSNEEVAeaitQFLPNCDPDDPHRYTLAAQDLVMRARGVLKD ... ..|...|||||..| ||.... ..| . . |... |.|. |...|| . .| sfevkkgDiillatDGvfDnlsedqil----eelkelkerdeeelqllanslaekareLsfd |
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| Phosphatase | PPM1H.AA | Family.PPTC7.PD | 262-305 | 34 | 1e-07 | 22.1 | In-house | 93-138 (262) | Show / Hide |
Range on Protein: 262-305 Range on HMM: 93-138/262 Sequence Identity: 34% (15 aa) SYNISGGCTALIVIC--LLGKLYVANAGDSRAIIIRNGEIIPMSSE . |..||..|. ||..|| ||| ...|.|... |.| kvpvvGsstAcvvvldredkklesanlGDsgflvvRegkvvhrske |
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| Phosphatase | PPM1H.AA | Subfamily.PPTC7.PD | 262-305 | 39 | 1.1e-07 | 21.9 | In-house | 94-139 (263) | Show / Hide |
Range on Protein: 262-305 Range on HMM: 94-139/263 Sequence Identity: 39% (17 aa) SYNISGGCTALIVICLLG--KLYVANAGDSRAIIIRNGEIIPMSSE . |..|| ||. ||..|| ||| ...|||... |.| kvpvvGsstacivvldredkklesaNlGDSgflVvRngkvvhrske |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1K.PD | 378-454 | 28 | 1.9e-07 | 20.7 | In-house | 168-233 (264) | Show / Hide |
Range on Protein: 378-454 Range on HMM: 168-233/264 Sequence Identity: 28% (22 aa) KKARVMATIGVTRGLGDHDLKVHDsnIYikpflsSAPEVRIYdlsKYDHGSDDVLILATDGLWDVLSNEEVAEAITQ | .| . . .|| ||| ||| . . . || . | .|..| |.| |||. .|....|... ... gkplvnsrlamtrslGdldlkryG--vi------atPetksl---kvkhaadsflvlitdgisfvvnsqelcdlvrl |
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| Phosphatase | PPM1H.AA | Subfamily.ILKAP.PD | 135-176 | 37 | 2.7e-06 | 17.0 | In-house | 38-79 (298) | Show / Hide |
Range on Protein: 135-176 Range on HMM: 38-79/298 Sequence Identity: 37% (15 aa) ENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQD ....|. . |...||||||| |. | . |...| |.| rkekskvsrvsyyavfDGhaGsrasefaaeklhkviveklpk |
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| Phosphatase | PPM1H.AA | Subfamily.PPM1A.PD | 144-174 | 35 | 9.4e-06 | 15.1 | In-house | 41-71 (309) | Show / Hide |
Range on Protein: 144-174 Range on HMM: 41-71/309 Sequence Identity: 35% (10 aa) CHYWSLFDGHAGSGAAVVASRLLQHHITEQL ....||||||| .. .... | ..|.|. wsffavfDGHaGskvskycakhlleaileee |
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