Gene PPM1M
PPM1M
Species: Human
Alias: PP2Ceta, PPM1M, FLJ32332, PP2C-eta, PP2CE
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPM1M.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPM1M.AA | Subfamily.PPM1H.PD | 63-447 | 57 | 2e-172 | 563.6 | In-house | 4-402 (402) | Show / Hide |
Range on Protein: 63-447 Range on HMM: 4-402/402 Sequence Identity: 57% (227 aa) RGRTLPWNAGYAEIINAEKSEFNEDQAACGKLCIRRCE-----FGAEEEWLTLCPEEFLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGLVA | |||.|||||.|||.|||.||||||. .|.....| .|.|||. . . || |. .|..|||||.|..||..|...||..|...||.|.| |.... dlrklPwaaGYaevinagkselneDqaaakvlllkkkesvtskageeeelkekskeeklplayfglfDGhaGsgaalvaskllhkhlkekledvlellle TQ-PPMHL-NGRCICPSDP--QFVEEKGIRAEDLVIGALESAFQECDEVIGRELEASGQMGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEF ....| ..|. .|..| .||||| |..|.||||||||||.|.||.| || || ..||||||||. |.||||.||||||||||||.|||.||| .||| ksaeklalgeerkeaptepseifveekkiskeeLviGalesaflemDeqiarereayrikGGCtalvalvllgklYvanaGDsRailvrkdeiiplsadf TPETERQRIQQLAFVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQL ||||||.|.|||..||||. |||||||..||| .||||.||.||..|.||.||.||..|||.|||.|.|..||||.|..|.||||||.|.|.|||...|| tPeteRqRlqelaflkPeLlgkeftrlefqkRlkkkdlgqrvlyRdqnmtGWayktveeeDlkfplisgegkkaRllatigvtRGlGDheLkvvdtnlsi KPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPG-NQEDPHRFSKLAQMLIHSTQGKEDS----LTEEGQVSYDDVSVFVI || .||.|.|||..|.| .||||...||||||||||||.||..||..|. ..||..|....||.|.....||... |.||...|.||.||||| kPfLspvPevrvldltqvesleDdvlilatDGLWdvlsneevaeivrevlskvdsedkkrytavaqeLvaaarGklkdkgWrlkeekaasvDDisvfvi |
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| Phosphatase | PPM1M.AA | Group.PPM.PD | 65-454 | 26 | 2.1e-72 | 234.2 | In-house | 34-326 (459) | Show / Hide |
Range on Protein: 65-454
Range on HMM: 34-326/459
Sequence Identity: 26% (102 aa)
RTLPWNAGYAEIInAEKSEFnEDQAA-CGKLCIRRcefgaeeewltlcpeefltgHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGLVATQPPMH
. ... |.|. ...| ||. . .. .....||||||..|| .||..|...| .||. . ... ...|.
sgnglrygvasmq-gwrkem-EDrhvivenfdnnd--------------------sffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeas
LNGRCicpSDpqfveekgiraeDLVIGALESAFQECDEVIGRELEASG---QMGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPE--TE
. . | .||.|||.|.|| . .| . .. . .|.||.||. ..|||.||||||||.|.| ....||| ...|| .||.|
ldndd---rg------------ekvkkalrsafleldedlseeanekeepgkdsGtTAvvalingkklyvANaGDSravLcrngkavplskdHkpenpeE
RQRIQQLAfvypellageftrlefprrlkgddlgqkvlfrdhhmsGWsykrveksdlkyplIHGQGrqaRLLGTLAVSRGLGDHQLRVldtniqLKPFLL
|.... |. .. .| |..|.|||||.||||.|.... . |.|.|....
reRIekag-------------------------------------Gs--------------veidg---RvnGilavsRalGdhdlkk------eeqmvs
SVPQVTVLDVDqlelQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPG-NQEDPHRFSKLAQMLIHSTQGKEdsLTeEGQVSYDDVSVFVIPLHSQGQ
.||...|.|.||||||||||.|. .||. | ..|. ..... |..|. .. .| | . . |.|...|.|. |.. .
aePdvsvvklt----eedeflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakg--st-gdgtscDNiTvivvtlndamr
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| Phosphatase | PPM1M.AA | Family.PPM.PD | 64-456 | 26 | 1.2e-66 | 215.1 | In-house | 10-293 (495) | Show / Hide |
Range on Protein: 64-456
Range on HMM: 10-293/495
Sequence Identity: 26% (102 aa)
GRTLPWNAGYAEIInAEKSEFnEDQAACgklcirRCEFGAEEewltlcpeeflTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGLVATQPPMH
. ....|.|. ..|| ||. . ... .| . .....|||||| .|| .||..||..| .||| . . . .|..
sssnglrygvasmq-gwrsem-eDahvv------venlenne-----------dfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaess
LngrcicpsdpqfveekgiraeDLVIGALESAFQECDEVIGRELEASG--QMGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPE--TER
. | ||..||.|.|| . .||. . . .|.||.|.. ..|||.||||||||.|.|. ....|| ...|| .||.||
a---------------------ekvkealrkafleldeelseelneksagkdsGtTAvvvlirgkklyvAnaGDsravLcrngkavelskdHkpenpeEr
QRIQQLAfvypellageftrlefprrlkgddlgqkvlfrdhhmsGWsykrveksdL-KyplihgqgRQARLLGTLAVSRGLGDHQLRVldtNIQLkpFLL
.... |. . |..|. |.|||||.|||..|. |. .. ..|..|..
eRIekag-------------------------------------Gk---------vvi--------rdgrvnGvlavsRalGdfdlkk---eeqa--ivs
SVPQVTVLDVDqleLQEDDVVVMATDGLWDVLSNEQVAWLVRSFLpgnQEDPHRFSKLAQMLIHSTQGKEDSlteegqvsyDDVSVFVIPLHSQGQES
... .||...|.|.||||||||||.|. |||. | .|. ......|..|... | . |...|.|. |. . ...
aePditsvklt---qeedeflvlasdGlWdvlsneevvelvretl---eekeedleeiaeeLvdealakgsr---------DNiTvlvvalyenikqq
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| Phosphatase | PPM1M.AA | PP2Cc | 67-447 | 17 | 5.4e-47 | 163.37 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 67-447
Range on HMM: 1-338/338
Sequence Identity: 17% (82 aa)
LPWNAGYAEIINAE-------KSEFNEDQAACGKLCIRRCEFGAEEEWLTLCPEEFLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVE------
. . . . .... . .|| .| . ..||||||...| ... ||..| ..|... .
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP--------------------------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKEN
--GLVATQPPMHLNGRCICPSDPQFVEEKGIRAEDLVIGALESAFQECDEVIGRELEASGQMGGCTALVAVSLQGKLYMANAGDSRAILVRRDE------
. . .| .. . .. ... .... ||..||...|| | |||.||. .||| ||.|||||.| | ..
DEMQ-D-EP---------EMW-W-R-MW-HDKWFEDWEDALRKAFLRMDEEI------------CTAVVALIRGNKLYVANVGDSRAVLCRNGNDNWWGI
----IRPLSFEFTP--ETERQRIQQLA---FVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQ--ARLLGT--
...|... .| |.||.||.|. . . .. . .|..|.
RHYTAHQLTEDHKPDNEDERRRIEQAGGRVM----------------------------------------------P-MHRQWVMNWNCDVWRVNGVPI
-LAVSRGLGDHQLRVLD----------------TNIQLKPFLLSVPQVTVLDVDQLEL---QEDDVVVMATDGLWDVLSNEQVAWLVRSFL---------
||||| .|||... . ...|.. ..|.||. . .| . ..|| .....||||||.||..| ..||..|
PLAVSRAFGDHYYKW-KEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQM-TVPTPDDDFLILCCDGLWDVMSNQEVVDIVRKCLRKWHHKPVK
-------------PGNQEDPHRFSKLAQMLIHSTQGKEDSLTEEGQVSYDDVSVFVI
... .|| . .|. .. |...| |.
NQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----------------CDNMTVIVV
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| Phosphatase | PPM1M.AA | Subfamily.PPM1G2.PD | 119-263 | 28 | 4.6e-22 | 68.5 | In-house | 44-157 (275) | Show / Hide |
Range on Protein: 119-263 Range on HMM: 44-157/275 Sequence Identity: 28% (41 aa) HYWALFDGHGGPAAAILAANTLHSCLRRqleavveglvatqppmhlngrcicpsdpqfveeKGIRAEDLVIGALESAFQECDEVIGRELEASGQMGGCTA ..|.|||||| ..| |.. |.. . . | .|. . .|. || |.|| . .. .. .. |.||.| alfavfDGhGGakvakyagkklikkiak---------------------------------kksfkegaleqilkdafletDeellkdeklkdesaGsta LVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPET--ERQRIQ .. . |||.||||||||.| . ... |||. |.. |..||. vvvlikeeklyvanaGDsravlsskgnvkalsfDhkPqeesekkrii |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1D.PD | 120-446 | 21 | 6.8e-20 | 61.5 | In-house | 43-310 (311) | Show / Hide |
Range on Protein: 120-446
Range on HMM: 43-310/311
Sequence Identity: 21% (72 aa)
YWALFDGHGGPAAAILAANTLHSCLRRQLEAvveglvATQPPMHlngrcicpsdpqfveekgiraedlVIGALESAFQECDEVIGRELEA-----SGQ--
. |.|||||| || | . | | ...| . ...| . |. |...|| .. | . ..|.||. | ||
fvavfDGHGGkeAakfarehlwsvikkqkkf------lsseped------------------------vleAireaflatheamkkklaeWpktksglls
MGGCTALVAVSLQGKLYMANAGDSRAILVRRDEirplsfeftpeTErqriqqlAFVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRD-HHMSGWSYKRve
| . . |||.|. |||...| ... .| .. .. | . . . . ..|| .| . . |. .|
taGttasvviirreklyvahvGDsgivlgvkep-----------ke-------kklrakeltkdHkPespeEkerieelGGevaaksGvkRvvWkRpr--
ksdlkY----PlihgqgRQARLLGTLAVSRGLGDhqlrVLDTNIQLKPFLLSvPQVTVLdVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQ
| .. . |||.| ||| . | . . .. | |. | | .|. .|......|.||||.||. |.. .|.. .. ..
-----lehngp------tvideiPFLavaRslGD----lWsynaksgeyvvs-PePdvk-vrtldpneekfiilasDGlwnvltpedavsvvekeeekke
EDPHRFSKLAQMLIHSTQGKedslTEEGQVSYDDVSVFV
.. |..|.... .. ... .. |.||| |
lkeeqsrsvakalvkealqr----wrskklraDnvsviv
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| Phosphatase | PPM1M.AA | Subfamily.PPM1A.PD | 325-409 | 38 | 3e-16 | 49.5 | In-house | 171-251 (309) | Show / Hide |
Range on Protein: 325-409 Range on HMM: 171-251/309 Sequence Identity: 38% (32 aa) RQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDqlelQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQED . |. |.||||| |||.. . . . . . . |.|||.. | .||. .|.|.||.|||.|||.|| .|.| | ... mikRvnGsLAvsRalGDydykekpekkateqlvspepevtvierd----eedeflvlacDGiwDvmsneevaefvksrlevtddl |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1A.PD | 111-264 | 26 | 3.8e-16 | 49.2 | In-house | 34-165 (309) | Show / Hide |
Range on Protein: 111-264 Range on HMM: 34-165/309 Sequence Identity: 26% (41 aa) CPEEFLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVveglvatqppmhlngrcicpsdpqfvEEKGIRAEDLVIGALESAFQECDEVIGRELEAS .|... . ..|.||||.| .. .|..|.. . .. | ..| . .. | ||...| |.||| .. | | lpsklkdwsffavfDGHaGskvskycakhlleaileeeefk--------------------------askeksskekvkealrkgfLelDekirklvels G--QMGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTP--ETERQRIQQ . |.|| |.. . |||.||.|||||.|.| . . . | ..|..||.. kgedksGsTavvvlvspkklylancGDsRavlsrngkvvfateDHkpsdpkEkeRien |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1E.PD | 119-265 | 30 | 3.8e-16 | 49.1 | In-house | 48-162 (269) | Show / Hide |
Range on Protein: 119-265 Range on HMM: 48-162/269 Sequence Identity: 30% (44 aa) HYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGLvatqppmhlngrcicpsdpqfveekgiraedlviGALESAFQECDEVIGRELEASGQMGGCTA ..| |||||| || ||. ||. | || .. . . ||..||...|| . . |. .|.|| |. affavfDGHgGveaakyaaahlhellvrqeklkedpa----------------------------------ealkeafkltDerflqkaereklksGsta LVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPET--ERQRIQQL . . .||.| |||.|.||| |.. | || |..||... vvvliekdqlyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieea |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1L.PD | 116-264 | 26 | 2.6e-14 | 43.3 | In-house | 40-166 (273) | Show / Hide |
Range on Protein: 116-264 Range on HMM: 40-166/273 Sequence Identity: 26% (40 aa) LTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVveglvatqppmhlngrcicpsD-------PqfveekgIRAEDLVigalESAFQECDEVIGRELE . .. |.|||||| || | . | ....| . | | | . |. .|| . ..... .. | tgesffavfdGhGGefaaefakdvlvkaiknkliel---------------------dadkentvp-------infskll----tdeilsvdekllekak ASGQMGGCTALVAVSLQGKLYMANAGDSRAILVRRDE-IRPLSFEFTPET--ERQRIQQ .|||.|. . .| .|| |||| .|. .. ||||. |. ||.||.. raediaGttalialvqesdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikk |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1G2.PD | 326-446 | 27 | 9e-14 | 41.3 | In-house | 165-274 (275) | Show / Hide |
Range on Protein: 326-446 Range on HMM: 165-274/275 Sequence Identity: 27% (33 aa) QARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDqlelQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNqedpHRFSKLAQMLIHSTQ | |.||.|| |||.. . .. || |.| ..| ..|. .|.| ||.||||.|..| |||. | . .. ..... |.... . lnrvngnLalsralgDfefkknvkkkpeeqivtavPDvlvkkld----eddeflvLaCDGiWDvltnkevvdlvrerlvsg----akldeiieelldkcl GKEdslTEEGQVSYDDVSVFV . .... | |...| . apd---ssntgvGcDnmtvvi |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1E.PD | 326-425 | 32 | 2.6e-12 | 36.6 | In-house | 171-254 (269) | Show / Hide |
Range on Protein: 326-425 Range on HMM: 171-254/269 Sequence Identity: 32% (32 aa) QARLLGTLAVSRGLGDHQlrvldtniqLKPFLLSVPQVTVLDVDQlelqEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQEDphrFSKLAQMLIHSTQ . | |.|.||| .|| . |||.. . ..|. ...|. ..|....|.||||||. .|.| ||..|| ..|| |..|..|... . awRvnGvLsvsRaiGDvk---------lkpyvsgeadvaeveldg----sedylilacDGlwDvvneeevvklveefladgaed---lsevakllveaak |
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| Phosphatase | PPM1M.AA | PP2C | 328-415 | 28 | 9.2e-12 | 43.87 | Pfam | 184-269 (284) | Show / Hide |
Range on Protein: 328-415 Range on HMM: 184-269/284 Sequence Identity: 28% (26 aa) RLLGT-LAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVT-VLDVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQEDPHRFSK |. |. ||||| .||... .| .. ..|..| . ... ..|. ...|.||||||.|...| .||... .. || .... RVNGVWLAVSRAFGDFHYKPNHTCFPKEQPVTAEPDITPEH---KITPDHDEFLILACDGLWDVMSDQEVCDIVRQCRSDWN-DPMEACE |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1G.PD | 200-263 | 39 | 5.2e-11 | 32.4 | In-house | 294-358 (482) | Show / Hide |
Range on Protein: 200-263 Range on HMM: 294-358/482 Sequence Identity: 39% (26 aa) DEVIGRElEASGQMGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPE--TERQRIQ ....|.. | |. |.||.||. . ||..|||||||..| | . ||.. || .|..||. edllgks-eepGkdsGttavvaLvkgkklivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRie |
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| Phosphatase | PPM1M.AA | Subfamily.PDP.PD | 325-415 | 31 | 6e-11 | 32.3 | In-house | 234-338 (409) | Show / Hide |
Range on Protein: 325-415 Range on HMM: 234-338/409 Sequence Identity: 31% (33 aa) RQARLLGTLAVSRGLGDHQLRV---LDTNI--------QLKP-FLLSVPQVTV-LDVDQLELQ-EDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQEDP |. ||||.|| .| || ... |. .. .| . . | .| .| . .|. .| .|.|||||||.||||.|. || .|..... . rngRlLgeLaPlRAFGdvryKwskelqkkvlekllevkvvepkdyktPPYltaePevtshklrendkFLvlatDGLwdllsneevvslVgehlakkknka HRFSK .. kvaae |
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| Phosphatase | PPM1M.AA | Subfamily.ILKAP.PD | 322-408 | 29 | 7e-11 | 32.0 | In-house | 183-257 (298) | Show / Hide |
Range on Protein: 322-408 Range on HMM: 183-257/298 Sequence Identity: 29% (26 aa) GQGRQARLLGTLAVSRGLGDHQLRVLDtniqlkpfLLSVPQVTVLDVDQlelqEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQE |. |. |.|| |.||| .|| . . |. . | |.|. ..... .| ||.| ||||.|.....|. . . | ... gvvrdgRvlGvlevsRsiGDgrfkelg--------vistPdvkkceLte----nDlfvvlaCDGLwkvfeadevvkfilkvlededd |
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| Phosphatase | PPM1M.AA | Subfamily.TAB1.PD | 122-265 | 30 | 8.7e-11 | 31.3 | In-house | 40-194 (336) | Show / Hide |
Range on Protein: 122-265 Range on HMM: 40-194/336 Sequence Identity: 30% (49 aa) ALFDGHGGPAAAILAANTLHSCLR-RQLeavVEGlvATQPPMHLNGRCICPSDPQF-------VEEKG-IRAEDLVIGALESAFQECDEVIGRELEASG- |.|||. | || .....| . | .| | |.. |..| . | . .| |.|. ..... | ..... .| || | avfdGydGekaaefveqrLvaelllgdl---see--aeaepkllllqvieeverkffesiddavaeradlkstlpkgvasyeleekyeekinrlkelese QMGGCTALVAVSLQGKLYMANAGDSRAILVRRD----EIRPLSFEFTP--ETERQRIQQL || ||.||. | |||.|| ||||||||... ... || . . | | .|...| isgGttavvalilnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdL |
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| Phosphatase | PPM1M.AA | PP2C | 119-265 | 25 | 2.1e-10 | 39.0 | Pfam | 36-173 (284) | Show / Hide |
Range on Protein: 119-265 Range on HMM: 36-173/284 Sequence Identity: 25% (44 aa) HYWALFDGHGGPAAAILAANTLH------SCLRRQLEAVVEGLVATQPPMHLNGRCICPSDPQFVEEKGIRAEDLVIGALESAFQE--CDEVIGR---EL |. | |||||| || ....|| .|.... .| || ..|.| |... . . HFFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNP--------------------------------KDVEQALRKSFLECDTDMMFYSAPWHE EA----SGQMGGCTALVAVSLQGK--LYMANAGDSRAILVRRDEIR----PLSFEFTP--ETERQRIQQL .. . .||||..|. | || ||.|||||.| |..... .|.. .| | || ||.|. QNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQA |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1G.PD | 327-421 | 30 | 2.3e-10 | 30.3 | In-house | 368-457 (482) | Show / Hide |
Range on Protein: 327-421 Range on HMM: 368-457/482 Sequence Identity: 30% (29 aa) ARLLGTLAVSRGLGDHQLRVlDTNIQLKPFLLSvpqvTVLDVDQLELQ-EDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQEDpHRFSKLAQMLI | | | .|| |||| . .... .. ..| . |. .| |. ||. .|.|.||.|.|.| ..| ||. | ..|. .. |... |. gRvnGGLnlsRalGDhaYkt-neeLpaeeqmis----alPDikklilteedeFlvlacDGiWnvmssqevvdFvraklkesees-kklseiceeLl |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1K.PD | 191-264 | 37 | 4.4e-10 | 29.2 | In-house | 76-157 (264) | Show / Hide |
Range on Protein: 191-264 Range on HMM: 76-157/264 Sequence Identity: 37% (30 aa) ALESAFQECDEVIGRELEAS-----GQMGGCTALVAVSLQGK-LYMANAGDSRAILVRRDEIRPLSFEFTPE--TERQRIQQ | ||.|.|. . | || | . | || |.. .|. | .|. ||||||| |. . . |. . .|| .|..||.. vlkqafeeldkklkrylefsvaeaellssGttatvsllrdGnelvlaslGdsrailcrnGkakkltkdhdPerkeekerika |
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| Phosphatase | PPM1M.AA | Subfamily.LRR-PP2C.PD | 326-397 | 33 | 1.4e-09 | 27.7 | In-house | 163-222 (257) | Show / Hide |
Range on Protein: 326-397 Range on HMM: 163-222/257 Sequence Identity: 33% (23 aa) QARLLGTLAVSRGLGDhqlrvldtnIQLKPFLLSVPQVTVldvDQLELQEDDVVVMATDGLWDVLSNEQVAW .|. ||||||| ||| . |.||... |... ..| ...| ||.||..|.|. tsrvnGtlavsralGd---------sflePfvvpdPdlsq---sleiskkdkflilacdGiwdlisdeeave |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1L.PD | 328-401 | 32 | 1.7e-09 | 27.5 | In-house | 178-241 (273) | Show / Hide |
Range on Protein: 328-401 Range on HMM: 178-241/273 Sequence Identity: 32% (24 aa) RLLGTLAVSRGLGDHQLRvlDTNiqlkpFLLSVPQVTVLDVDQLelqEDDVVVMATDGLWDVLSNEQVAWLVRS |. | ||.|| |||. |. | | .... |.. .|.|.. . . ...|.||||| .|||. .. rvaGvlatsralGdyplk--dkn-----lviadpdiltfdlddh---kpeflilasdGlwdtfsneeavrfike |
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| Phosphatase | PPM1M.AA | Subfamily.LRR-PP2C.PD | 192-265 | 31 | 6.7e-09 | 25.5 | In-house | 81-153 (257) | Show / Hide |
Range on Protein: 192-265 Range on HMM: 81-153/257 Sequence Identity: 31% (24 aa) LESAFQECDEVIgrelEASGQMGGCTALVAVSLQGKLYMANAGDSRAILVRRDEI-RPLSFEFTPE--TERQRIQQL |. |..| . | . ... |.|| ... .. | |.|| ||||..| ..| . . ||.. | |..||..| lkkaykeistqi----serpkfiGttaasvliiedkvyianvGdsrvvlcqkdgtakrlsldhkPseeseekrisel |
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| Phosphatase | PPM1M.AA | Subfamily.ILKAP.PD | 191-245 | 35 | 1.5e-08 | 24.3 | In-house | 92-148 (298) | Show / Hide |
Range on Protein: 191-245 Range on HMM: 92-148/298 Sequence Identity: 35% (20 aa) ALESAFQECDEVIGRELEASG--QMGGCTALVAVSLQGKLYMANAGDSRAILVRRDE .| ||.. || . .. ... |.|| |.. .. .||.|| |||.|.|.|..| clvdafkktDeeflklaskakPvWkdGstavvvlvvdnvlyvanlGDskavlaRake |
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| Phosphatase | PPM1M.AA | Family.PPTC7.PD | 367-421 | 27 | 4e-08 | 23.3 | In-house | 169-220 (262) | Show / Hide |
Range on Protein: 367-421 Range on HMM: 169-220/262 Sequence Identity: 27% (15 aa) DVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFlpgNQEDPHRFSKLAQMLI | . |....|....||||..| ||..|. .. ...|... .||. |. dstsfevkkgDiillatDGvfDnlsedqileelkel---kerdeeelqllansla |
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| Phosphatase | PPM1M.AA | Subfamily.PPTC7.PD | 368-419 | 24 | 9.6e-08 | 22.0 | In-house | 171-219 (263) | Show / Hide |
Range on Protein: 368-419 Range on HMM: 171-219/263 Sequence Identity: 24% (12 aa) VDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFlpgNQEDPHRFSKLAQM . |....|....||||..| ||.... .. ...|... ||. stsfevkkgDlillatDGvfDNlsedeilevlkel---kerdeeelqllans |
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| Phosphatase | PPM1M.AA | Subfamily.PDP.PD | 121-245 | 23 | 2.2e-07 | 20.6 | In-house | 40-196 (409) | Show / Hide |
Range on Protein: 121-245 Range on HMM: 40-196/409 Sequence Identity: 23% (37 aa) WALFDGHGGPAAAILAANTLHSCLRRQL--EAVVE-----------GLVATQPPMHLNGRCICPSDPQFVE------EKGI-RAEDLVIGALESAFQECD ..|||||| |.| . | . . .| . |.. | .. . | . | . . | .. . |. | ||..||...|. fgvfDGHggaacaeavskrLlkyvaasllkkqvlleaeeaekslkellsilklekkpndsvlkeskklykeslkkyvqelleakelkveealkkaFlrlD EVIGRELEAS------------GQMGGCTALVAVSLQGKLYMANAGDSRAILVRRDE | | .. . | .||.|. . .|..||.||.||.| ...| kdislealkkleekvleeavlkvalsGacallaliegtelhvAntGDcravlgvqee |
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| Phosphatase | PPM1M.AA | Subfamily.ILKAP.PD | 119-148 | 44 | 1.6e-06 | 17.7 | In-house | 48-77 (298) | Show / Hide |
Range on Protein: 119-148 Range on HMM: 48-77/298 Sequence Identity: 44% (13 aa) HYWALFDGHGGPAAAILAANTLHSCLRRQL |.|.||||.|. |. .||..||... ..| syyavfDGhaGsrasefaaeklhkvivekl |
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| Phosphatase | PPM1M.AA | Subfamily.PPM1K.PD | 119-149 | 50 | 4.3e-06 | 16.1 | In-house | 38-68 (264) | Show / Hide |
Range on Protein: 119-149 Range on HMM: 38-68/264 Sequence Identity: 50% (15 aa) HYWALFDGHGGPAAAILAANTLHSCLRRQLE | |.||||||..|| . . |. ..|| || lyfavfdGhgGssaadfvhdkleeivrrlle |
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| Phosphatase | PPM1M.AA | Subfamily.LRR-PP2C.PD | 119-150 | 50 | 5e-06 | 16.1 | In-house | 41-72 (257) | Show / Hide |
Range on Protein: 119-150 Range on HMM: 41-72/257 Sequence Identity: 50% (16 aa) HYWALFDGHGGPAAAILAANTLHSCLRRQLEA .|.|||||||| ||| |...|. |. |.. dyyalfdGhgGraaakfaseelykilaelldl |
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