Gene PPM1K
PPM1K
Species: Human
Alias: PP2Ckappa, DKFZp667B084, PTMP, PPM1K, hPTMP, DKFZp761G058, PP2Cm, UG0882E07
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPM1K.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPM1K.AA | Subfamily.PPM1K.PD | 84-346 | 67 | 1.2e-146 | 477.0 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 84-346 Range on HMM: 1-264/264 Sequence Identity: 67% (179 aa) GKPIPKISLENVGCASQIGKRKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLS-ADAT ||||||||...||..|.||||.||||||....|....|||||.|||||..||||.|...|.....||.|||.||..|. ||.|.||........| |.|. gkpipkisvdsvGkdsliGkraenedrfklkeldpdllyfavfdGhgGssaadfvhdkleeivrrllekekdleevlkqafeeldkklkrylefsvaeae LLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKR ||.|||||||.|||||.|||.||.|||||||||.||..|||.||.||||.||||||..||.|.|||||.|.||.|||||||.||||||..||||.||||. llssGttatvsllrdGnelvlaslGdsrailcrnGkakkltkdhdPerkeekerikaagGsvewnslgkplvnsrlamtrslGdldlkryGviatPetks IKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF .|..||.||||||.||||.|.|||||.||.|..||||.||||||||||.|||.|||.||||||. lkvkhaadsflvlitdgisfvvnsqelcdlvrlchdpeeaahavteqalqygsednatavvvpl |
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| Phosphatase | PPM1K.AA | Group.PPM.PD | 94-349 | 35 | 6.1e-77 | 249.2 | In-house | 39-324 (459) | Show / Hide |
Range on Protein: 94-349 Range on HMM: 39-324/459 Sequence Identity: 35% (103 aa) NVGCASQIGKRKENEDRFDFAQLTDE-VLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKE-------------------KNLETLLTLAFLEIDKAFSS ..|.|| |.|||.|||. .. |. .|.|.|||||..||.|.. .. |... |.|. ..... |. ||||.|...|. rygvasmqgwrkemEDrhvivenfdnndsffgVfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvkkalrsafleldedlse HARLSAdATLLTSGTTATVALLrDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSlgqpHVNGRLAMTRSIGDLDLKTsG .|. . .|||||.|||. .| .|.|| .|||||.|||.||...|..||.||...|.|||.| ||.| ... ||| ||..|..|||||. . eaneke-epgkdsGtTAvvali-ngkklyvANaGDSravLcrngkavplskdHkpenpeEreRIekagGsveidg----RvnGilavsRalGdhdlkk-e ---VIAEPETKRIKLHHAdDSFLVLTTDGINFMVNSQEICDFVNQCHDP---------NEAAHAVTEQAIQYGTE------DNSTAVVVPFGAW |.|||... .|| .. | |||| .||. .....|...||.. . .|.| .. ..|.. |.. || |..|| . eqmvsaePdvsvvkltee-deflvlAsDGlWdvlsneevvefvretlekkkkelkkdleeiaerlvdealakgstgdgtscDNiTvivvtlnda |
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| Phosphatase | PPM1K.AA | Family.PPM.PD | 94-349 | 35 | 2.1e-76 | 247.4 | In-house | 16-289 (495) | Show / Hide |
Range on Protein: 94-349 Range on HMM: 16-289/495 Sequence Identity: 35% (98 aa) NVGCASQIGKRKENEDRFDFAQLTD---EVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKE-------------KNLETLLTLAFLEIDKAFSSHARL ..|.||. |.|.|.||.. ... . .. .|.|.||||| .||.|.. .. |.. . | |. ..... |. ||||.|...|.... rygvasmqgwrsemeDahvvvenlennedfslfgvfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkafleldeelseelne SAdaTLLTSGTTATVALLRDGIeLVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWnslGQPHVNGRLAMTRSIGDLDLKT---SGV . .|||||.|.|.|.. |.|| .|||||.|||.||...|. ||.||...|.|||.| ||.| . .. ||| ||..|..|| |||. .| ks--agkdsGtTAvvvlirgkk-lyvAnaGDsravLcrngkavelskdHkpenpeEreRIekagGkvvi---rdgrvnGvlavsRalGdfdlkkeeqaiv IAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCH-----DPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAW .|||... .|| . .| |||| .||. .....|....|.. |..|.|... ..|...|..|| |..|| . saePditsvkltqeedeflvlasdGlWdvlsneevvelvretleekeedleeiaeeLvdealakgsrDNiTvlvvalyen |
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| Phosphatase | PPM1K.AA | PP2Cc | 84-344 | 26 | 5.2e-72 | 246.45 | SMART | 1-338 (338) | Show / Hide |
Range on Protein: 84-344
Range on HMM: 1-338/338
Sequence Identity: 26% (96 aa)
GKPIPKISLENVGC--ASQIGKRKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKN--------------------------
.. | .|. |. | |...||.. .|.|.|||||...|..|. |. ... |...|
HS-MGYNSGWRYGYMESSMQGWRHPMEDAHVCRP------FFGVFDGHGGHECAQYCRKHLHEHLAEELQFHKDDDYKENDEMQDEPEMWWRMWHDKWFE
-LETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGK----------PMKLTIDHTPERKDEKERIKKCGGFV
.| .| |||..|... .||.|||.|.. | ||.||||||.|||.|. . || ||.|.. ||..||...|| |
DWEDALRKAFLRMDEEI----------------CTAVVALIRGNK-LYVANVGDSRAVLCRNGNDNWWGIRHYTAHQLTEDHKPDNEDERRRIEQAGGRV
A-----WNSLGQ---PHVNGR---LAMTRSIGDLDLKT-----------------------SGVIAEPETKRIKLH-----HADDSFLVLTTDGINFMVN
. | . .. . |||. ||..|..|| ..|. ..|||||... ..|. || ||.| .||. ...
MPMHRQWVMNWNCDVWRVNGVPIPLAVSRAFGDHYYKWKEDEKIEWNRWYQMFDPRLPFKEPYVIAEPDVTHHELWQMTVPTPDDDFLILCCDGLWDVMS
SQEICDFVNQCH---------------------------DPNEAAHAVTEQAIQYGTEDNSTAVVV
.||..|.| .| || ||| . ..|| .|| |..||
NQEVVDIVRKCLRKWHHKPVKNQAQENAHMMRHRQKKHNDPMEAAKRLCDCAI----CDNMTVIVV
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| Phosphatase | PPM1K.AA | PP2C | 122-339 | 35 | 7.2e-55 | 193.4 | Pfam | 37-284 (284) | Show / Hide |
Range on Protein: 122-339 Range on HMM: 37-284/284 Sequence Identity: 35% (90 aa) YFAVYDGHGGPAAADFCHTHME----KCIMDLLPKEKN----LETLLTLAFLE--IDKAFSSHARLSADA--T--LLTSGTTATVALLRDGI-ELVVASV .|||.||||| ||..|. |.. .. . .| | .||| .| .| | |. .... . ..||.||..|..|. | || . FFAVFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYS-APWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANC GDSRAILCRKGKPM----KLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGR-LAMTRSIGDLDLK-------TS-GVIAEPETK-RIKLHHADDSF |||||.|||.|.. || ||.|.. ||..||.. ||.| | |. ||| ||..|..||...| .. .|.|||.. .|. .| | GDSRAVLCRNGNAHNWVHQLTYDHKPSNEDERRRIRQAGGWVMWW--GFWRVNGVWLAVSRAFGDFHYKPNHTCFPKEQPVTAEPDITPEHKITPDHDEF LVLTTDGINFMVNSQEICDFVNQC-HD---PNEAAHAVTEQAIQYGTEDNS |.| .||. ....||.||.| || .| |.||. . . .|.||.||| LILACDGLWDVMSDQEVCDIVRQCRSDWNDPMEACEKLVDYCIAYGSEDNI |
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| Phosphatase | PPM1K.AA | Subfamily.PPM1E.PD | 103-344 | 35 | 5e-54 | 173.4 | In-house | 21-267 (269) | Show / Hide |
Range on Protein: 103-344 Range on HMM: 21-267/269 Sequence Identity: 35% (91 aa) KRKENEDRF----DFAQLTD-----EVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARlsadATLLTSGTTATVA ||. |||. |. .| . | .|||.||||| ||.. .|. . ... ... .. | || ..|..| ..| |.||.|| |. krrkmEDrhvaledlnelfelkdekeraffavfDGHgGveaakyaaahlhellvrqeklkedpaealkeafkltDerflqkae----reklksGstavvv LLRDGIeLVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNslGQPHVNGRLAMTRSIGDLDLKTSgVIAEPETKRIKLHHADDsFL |.. | || .|||.|.|.|||. ..|. | |||.|||.||.. ||.| . |. ||| |...|.||| .|| |..|... ...|....| .| liekdq-lyvaWlGDsqallvrkgeavqlmkpHkPeredEkkRieeagGlvvvi--gawRvnGvLsvsRaiGDvklkpy-vsgeadvaeveldgsed-yl VLTTDGINFMVNSQEICDFVN-----QCHDPNEAAHAVTEQAIQYGTEDNSTAVVV .|..||. .|| .|... |. . .| .|.|. . |.|.. | .|| |.||| ilacDGlwDvvneeevvklveefladgaedlsevakllveaakeagssDnitvvvv |
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| Phosphatase | PPM1K.AA | Subfamily.PPM1A.PD | 95-348 | 30 | 2.2e-53 | 171.6 | In-house | 12-280 (309) | Show / Hide |
Range on Protein: 95-348 Range on HMM: 12-280/309 Sequence Identity: 30% (86 aa) VGCASQIGKRKENEDRFD----FAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDL--------LPKEKNLETLLTLAFLEIDKAFSSHARLSADAT .| .|. | | | || . ... ... .|||.|||.| .. .| .|. . |.. ....... | .|||.|.. ....||. . yglssmqgwRvemEDahtavidlpsklkdwsffavfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekirklvelskged llTSGTTATVALLRDGiELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNslgqpHVNGRLAMTRSIGDLDLKTS--------GV ||.||.|.|... .|..| .|||||.|.|.|| . | || | ...|||||.. ||.| . ||| ||..|..|| | |.. | --ksGsTavvvlvspk-klylancGDsRavlsrngkvvfateDHkpsdpkEkeRienAgGsvmik-----RvnGsLAvsRalGDydykekpekkateqlv IAEPETKRIKLHHADDsFLVLTTDGINFMVNSQEICDFVNQC----HDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGA ..|||.. |. .. |. ||||..||| .....|...||.. .|..|.|... ..... |..|| ....| . . spepevtvierdeede-flvlacDGiwDvmsneevaefvksrlevtddleevanelldtcLekgsrDNmsvilvllpg |
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| Phosphatase | PPM1K.AA | Subfamily.LRR-PP2C.PD | 94-344 | 32 | 2.4e-47 | 151.6 | In-house | 11-255 (257) | Show / Hide |
Range on Protein: 94-344 Range on HMM: 11-255/257 Sequence Identity: 32% (81 aa) NVGCASQIGKRKENEDRFD----FAQLTDEVlYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKN-LETLLTLAFLEIDKAFssharlsA--DatlLTS .|| . ||.| ||.. | . .|| |.|..||||| |||.|. ...| . .|| .. . |. |. ||. .. ||||... kvgfsdmiGrrptmedelviyGsfrdksded-yyalfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqi-------serp---kfi GTTATVALLRDGiELVVASVGDSRAILC-RKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNsLGQPHVNGRLAMTRSIGDLDLKtSGVIAEPETKRIKL |. . ..| |||||..|| ..| .|..|| | ..|..||.. ||.| . ||| ||..|..|| |. |...|. .. . .| | Gttaasvliied-kvyianvGdsrvvlcqkdgtakrlsldhkPseeseekriselGGtvvst-vvtsrvnGtlavsralGdsfle-PfvvpdPdlsqsle HHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVV |.|. ||| .. .| .. | . ||..|| . ..| . |..|| . .|. iskkdkflilacdGiwdlisdeeaveivagisdpekaaeklrdlayssGstdnisvivi |
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| Phosphatase | PPM1K.AA | Subfamily.PPM1L.PD | 93-346 | 34 | 4.4e-46 | 147.6 | In-house | 12-273 (273) | Show / Hide |
Range on Protein: 93-346 Range on HMM: 12-273/273 Sequence Identity: 34% (92 aa) ENVGCASQIGKRKENEDRFDFAQL-TDE--VLYFAVYDGHGGPAAADFCHTHMEKCIMDLL-----PKEKNL----ETLLTLAFLEIDKAFSSHARLSAD .|| | |.|.. ||||.... ... .|||.||||| ||.|.. . | |.. | ||... ..||| | .|. ..|. . | qnvavysvlGrrprmedrfeieediknktgesffavfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekakraed atllTSGTTATVALLRDgIELVVASVGDSRAILCR-KGKPMKLTIDHTPERKDEKERIKKCGGFVAWNslGQPHVNGRLAMTRSIGDLDLKTSG-VIAEP ..|||| .||... .|.|| ||||| .|. .|| . |. || |.. |. |||| |||.|.. | |.| ||..|..|| || |||.|. ----iaGttalialvqe-sdlivanvGdsrGvlydkrGkaiplsfdhkpqqvkerkrikkaGGfiafr--GvwrvaGvlatsralGdyplkdknlviadp ETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVN-QCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF ..|.. . ||.|..||. .| . |. . ..|. |.... .. . |. || | .|| . diltfdlddhkpeflilasdGlwdtfsneeavrfikerlkepdfGakslvlesfkrGsvdnitvlvvkl |
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| Phosphatase | PPM1K.AA | Subfamily.PPM1G2.PD | 117-337 | 34 | 8.8e-44 | 139.8 | In-house | 40-258 (275) | Show / Hide |
Range on Protein: 117-337 Range on HMM: 40-258/275 Sequence Identity: 34% (78 aa) TDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLL-PKEKNLETLLTLAFLEIDKAFSSHARLSADatllTSGTTATVALLRDGIeLVVASVGDSRAILCR .... .|||.||||| ..| .. ... | |. || .||..| ||||.|. . .. .|. . ..|.||.|.|... |.||.|||||.|. | dkslalfavfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkdeklkde----saGstavvvlikeek-lyvanaGDsravlss KGKPMKLTIDHTPERKDEKERIKKCGGFVAWNslgqpHVNGRLAMTRSIGDLDLKTSG--------VIAEPETKRIKLHhADDSFLVLTTDGINFMVNSQ |. .|..|| |....||.||.. ||||. | ||| ||. |..|| |.. | |.|. ||.|| |||| ||| .....|.. kgnvkalsfDhkPqeesekkriiaagGfveln-----rvngnLalsralgDfefkknvkkkpeeqivtavPDvlvkkld-eddeflvLaCDGiWDvltnk EICDFVNQCHDPNEAAHAVTEQAIQYGTED |.|.. . . ....|. .. . evvdlvrerlvsgakldeiieelldkclap |
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| Phosphatase | PPM1K.AA | Subfamily.ILKAP.PD | 117-324 | 32 | 1.4e-43 | 139.4 | In-house | 44-259 (298) | Show / Hide |
Range on Protein: 117-324 Range on HMM: 44-259/298 Sequence Identity: 32% (72 aa) TDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPK------EKNLETLLTLAFLEIDKAFSSHARlsADATLLTSGTTATVALLRDGIeLVVASVGDSR .| |.||.|||.|. |..|......|.|.. ||| .|... |. || . |. | ..|. .. .|.||.|.|. | . ||| .|||.|.| vsrvsyyavfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflklas--kakPvWkdGstavvvlvvdnv-lyvanlGDsk AILCRKGK-----------PMKLTIDHTPERKDEKERIKKCGGFVAWNslgqpHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHAdDSFLVLTTDG .|. . .. |. |||| ..|..||.| ||.| . |.| |.. ||||| |..|||..|..|...| . | |.||. ||. avlaRakeegdkagestiasvlLskdHtpasyeerkriqkaGgvvrdg-----RvlGvlevsRsiGDgrfkelgvistPdvkkceLten-DlfvvlaCDG INFMVNSQEICDFVNQCHDPNEAAH .. .|. .|.... . .. . Lwkvfeadevvkfilkvlededdrk |
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| Phosphatase | PPM1K.AA | Subfamily.PPM1G.PD | 185-317 | 46 | 1.6e-32 | 103.4 | In-house | 306-440 (482) | Show / Hide |
Range on Protein: 185-317 Range on HMM: 306-440/482 Sequence Identity: 46% (59 aa) TSGTTATVALLRDGiELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSlgqpHVNGRLAMTRSIGDLDLK--------TSGVIA |||||.|||... .|.|| .||||..|.|.|| . | ||| || . |.|||.| || | . ||| | . | .|| |. | |. | | . dsGttavvaLvkgk-klivanaGDsRcvlsrnGkaldlsiDhkPeDeveleRiekaGGkvtldg----RvnGGLnlsRalGDhaYktneeLpaeeqmisa EPETKRIKLHHaDDSFLVLTTDGINFMVNSQEICDFVNQCH .| |||| .||| ...|||. |||.. lPDikklilte-edeFlvlacDGiWnvmssqevvdFvrakl |
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| Phosphatase | PPM1K.AA | Subfamily.PPM1D.PD | 97-323 | 29 | 5.1e-30 | 94.9 | In-house | 12-277 (311) | Show / Hide |
Range on Protein: 97-323 Range on HMM: 12-277/311 Sequence Identity: 29% (76 aa) CASQIGKRKENEDRFDFAQ------LTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMD---LLP-KEKNLETLLTLAFLEIDKAFSSHAR---LSADATL ... | || ||.. . . | ..||.||||| || | . |. . | . .| ..... . |||.. .| . ... .| |.||| seadqGgrkymeDvvaivlereesaeeaeaafvavfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpktksgll LTSGTTATVALLRDgIELVVASVGDSRAILCRKGK------PMKLTIDHTPERKDEKERIKKCGGFVA---------WNSLGQPhVNGR--------LAM |.| ..| .| || ||||...| | . . .|| || || .|||||...|| || |.. ||. ||..||.||| staGttasvviirr-eklyvahvGDsgivlgvkepkekklrakeltkdHkPespeEkerieelGGevaaksGvkRvvWkRprle-hngptvideiPFLav TRSIGDL---DLKTSGVI--AEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAA . |. . ||..| .|. ... |..|..||. ...... ..|.. . .| aRslGDlWsynaksgeyvvsPePdvkvrtldpneekfiilasDGlwnvltpedavsvvekeeekkelk |
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| Phosphatase | PPM1K.AA | Subfamily.PHLPP.PD | 122-344 | 23 | 1.7e-18 | 56.8 | In-house | 41-257 (257) | Show / Hide |
Range on Protein: 122-344 Range on HMM: 41-257/257 Sequence Identity: 23% (52 aa) YFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALlRDGIELVVASVGDSRAILCRKGKPMK . ..|| . | . ... . |.|| | .. .| ... . . ..|| .| | .| ||. ...|.| |||. | vyGlidGdrnselpsllqctmadvlkeevqkdkneevyianillvshrklGeaGqklGasallirikedrvdi-assftltaanvgkcklvlirnGkplp LTIDHTPERK-DEKERIKKCGGFVAWNSlgqpHVNGRLAMTRSIGDLDLKTSgVIAEPETKRIKLHHaDDSFLVLTTDGINFMVNSQEICDFVNQCHDPN . .. | .| .|||. ... .. .||| .. || .| | . |. .|. . ..| . .| .|.| ...... .|. . | . .|| || lskvyileiddeelkrikeakaiitedn----kvnGviestrilGytflfPv-vlPkphvrsvlLte-qdEllilGnkalWevlsideaveavrnvedpl EAAHAVTEQAIQYGTEDNSTAVVV ....| ||..|...|.|| vaAkklvdlaqsygaadsvsalvv |
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| Phosphatase | PPM1K.AA | Subfamily.TAB1.PD | 184-271 | 39 | 1.2e-15 | 47.5 | In-house | 135-223 (336) | Show / Hide |
Range on Protein: 184-271 Range on HMM: 135-223/336 Sequence Identity: 39% (36 aa) LTSGTTATVALLrDGIELVVASVGDSRAILCRKG----KPMKLTIDHTPERKDEKERIKKCGgfVAWNSLGQPHVNGRLAMTRSIGDLDLKT . |||| |||. .| || ||||||||... | .| ||. . .|| .|.|. | . . . | .. | ||||||. .|. isgGttavvali-lnnkLyvaNvGdsrAilvesekdgikvkQLsvdHnvdNedElkRlkdLG--ldieqikqnkrlgskeaTRsiGdykikk |
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| Phosphatase | PPM1K.AA | Subfamily.PDP.PD | 141-240 | 35 | 6.1e-14 | 42.2 | In-house | 111-223 (409) | Show / Hide |
Range on Protein: 141-240 Range on HMM: 111-223/409 Sequence Identity: 35% (40 aa) HMEKCIMDLLPK-EKNLETLLTLAFLEIDKAFSSHARLS-----ADATLL---TSGTTATVALLrDGIELVVASVGDSRAILCRK---G--KPMKLTIDH ...| . .||.. |...| |. |||..|| .| | . . ..| .||..|..||. .| || ||..||.||.|... | ...||..|. slkkyvqelleakelkveealkkaFlrlDkdislealkkleekvleeavlkvalsGacallali-egtelhvAntGDcravlgvqeeegsweavkLskdq TPERKDEKERIKKC | . ..| ||||| tadneeEveRikke |
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| Phosphatase | PPM1K.AA | Subfamily.PPM1G.PD | 94-177 | 31 | 2.3e-12 | 36.9 | In-house | 11-96 (482) | Show / Hide |
Range on Protein: 94-177 Range on HMM: 11-96/482 Sequence Identity: 31% (27 aa) NVGCASQIGKRKENEDRFDF-AQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLL-PKEKNLETLLTLAFLEIDKAFSSHARL ..|... | |.. || . .|.... ||||||||| | .| ... . . . || ..|. |. |||..|| . ... | sygasamqGWRvsmeDahncildldedtslfavyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkkllteeil |
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| Phosphatase | PPM1K.AA | Subfamily.PPM1H.PD | 160-240 | 41 | 4.6e-11 | 32.3 | In-house | 142-215 (402) | Show / Hide |
Range on Protein: 160-240 Range on HMM: 142-215/402 Sequence Identity: 41% (33 aa) LTLAFLEIDKAFSSHArlsaDATLLTSGTTATVALLRDGiELVVASVGDSRAILCRKGKPMKLTIDHTPERkdEKERIKKC | ||||.|. . .| .. | || |||. .| | || |||||||.||.. ..| |.||| |..|... lesaflemDeqiarer----eayrikGGCtalvalvllg-klYvanaGDsRailvrkdeiiplsadftPet--eRqRlqel |
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| Phosphatase | PPM1K.AA | Subfamily.PDP.PD | 274-331 | 29 | 3.1e-07 | 20.2 | In-house | 284-340 (409) | Show / Hide |
Range on Protein: 274-331 Range on HMM: 284-340/409 Sequence Identity: 29% (17 aa) VIAEPETKRIKLHHaDDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAI ..|||| ||.. .| |||| |||. .....|. . |.. . .. . |. ... ltaePevtshklre-ndkFLvlatDGLwdllsneevvslVgehlakkknkakvaaepa |
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| Phosphatase | PPM1K.AA | Subfamily.TAB1.PD | 103-171 | 27 | 9.7e-07 | 18.1 | In-house | 20-90 (336) | Show / Hide |
Range on Protein: 103-171 Range on HMM: 20-90/336 Sequence Identity: 27% (20 aa) KRKENEDRFDFaQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIM--DLLPK-EKNLETLLTLAFLEIDKAF . .||||.. . . .|.. .||.||. | ||.| . .. . .. ||. . | . . || .. |... | edhenedkvfs-rteddiilyavfdGydGekaaefveqrLvaelllgdlseeaeaepkllllqvieeverkf |
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| Phosphatase | PPM1K.AA | PP2C_SIG | 93-346 | 13 | 4e-06 | 11.81 | SMART | 1-250 (250) | Show / Hide |
Range on Protein: 93-346 Range on HMM: 1-250/250 Sequence Identity: 13% (39 aa) ENVGCASQIGKRKEN--EDRFDFAQLTDE--VLYFAVYDGHG--GPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTS . ... .|. . .. | .|| .. . . |.. |..| . ..| . . . .. ... .....| . |.. . DDHWDIYQYYEDATQVCGDWYDFWKIPEGQDRYFFVIGDVMGWAHGLPAALMMGMARTMMRTFWHE--SPPQILERCNRWIYQN---------NHEECGM GTTATVALL---RDGIELVVASVGDSRAILCRKGKPMKLTIDHTP---------ERKDEKERIKKCGGFVAWNSLG-QPHVNGRLAMTRSIGDLDLKTSG .||...... . .| ....|.|. | | .. ....... || .. . .... || .|.. .... FTTMCCCVYMPDFATHTLWYCHCGHSPPYLYRA-MDGGRVEHTHDHYLVQHYVMRIIDEEDAKHHPWHNWTGPPLGMEPDYM-------------YDVQE VIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQ-----------EICDFVNQCHDPNEAAH----AVTEQAIQYGTEDNSTAVVVPF . || .. .|. |||. ..|.| ..... |..| | |. . |.. ....|. | .|| . FQYEP-----------GDRFVMCTDGVTEARNPQGEFFGEEWLQEILEEHQ--CCCPQEIAQRIMQELMEHMGDHNGHDDMTVIVVKV |
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