Gene PPP1CA
PPP1CA
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPP1CA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPP1CA.AA | Family.PPP.PD | 27-301 | 56 | 8.10000000001e-139 | 452.6 | In-house | 65-341 (349) | Show / Hide |
Range on Protein: 27-301 Range on HMM: 65-341/349 Sequence Identity: 56% (156 aa) NVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH . ||...|. |. . .|.. ..|.|||.|||...|||||||..||||||. .|.||.. .||||||||||||.|.|.|.||.|.|..||..|||||||| kkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnh ECASINRIYGFYDECKRRY--NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKdVQGWGENDRGV |..|.|..||||.|.|..| . .....|...||.||.||..||||.|.||||||.|.|..|||.| ||...|..|||||||||||.. ..|| .|.||| EsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpee-qkgwkpnkRGv SFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADK .|.||...| |||.|..||||.|||.|||.||||||.|.|||.|||||||||..|..|...||..|..|....||... gfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskh |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP1C.PD | 30-299 | 91 | 2.6e-175 | 571.2 | In-house | 1-270 (271) | Show / Hide |
Range on Protein: 30-299 Range on HMM: 1-270/271 Sequence Identity: 91% (246 aa) LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS |.|.||| ||||.|||||||||||||||||||.|||||||.|||||||.||||||||||||||||||||||||||.|||||||||||||||||||||||| lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas INRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA |||||||||||||||||||||||.|||||||.||||||||||.||||||||.|.||||||.|||||||.|||||||||||||.|.||||||||||||||| inriygfydeckrryniklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfga EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA .||.|||.|||||||.||||||||||||||||||||||||||||||||||||.|||||.|.||||||||| dvvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilkpa |
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| Phosphatase | PPP1CA.AA | PP2Ac | 30-300 | 47 | 1.4e-166 | 560.58 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 30-300
Range on HMM: 1-321/321
Sequence Identity: 47% (153 aa)
LTENEIRGLCLKSREIFLSQPILLELE----APLKICGDIHGQYYDLLRLF---EYGG-FPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
....||. || ...||| ..| ..|.| .| ..|||||||..|||||| . .| .||..||.|||||||||..|.|.||||..|||.||.|||||
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL
RGNHECASIN---RIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSP------DLQSMEQIRRIMR----PTDVPDQGLLCDLLWS
|||||| ..| ..|||||||||.| . ..|| |..||...|..|... ||.| |||||| .... ..||.| | | . || ||.||||||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS
DP--------DKDVQGWGEND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVE----DGYEFFAKR-----QLVTLFSAPNYCGEFDNAGAMMSV----
|| |..|.||. | ||.|..||. || .|..|..||||.||||.|. |||||...| .|.|.|||||||...||..|.|.|
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK
------DETLMCSFQILKPAD
|. |.|.|. .||.
VIQYKMDKNLKCHFVQFKPQM
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| Phosphatase | PPP1CA.AA | Group.PPP.PD | 27-301 | 56 | 8.10000000001e-139 | 452.6 | In-house | 65-341 (349) | Show / Hide |
Range on Protein: 27-301 Range on HMM: 65-341/349 Sequence Identity: 56% (156 aa) NVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPES-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNH . ||...|. |. . .|.. ..|.|||.|||...|||||||..||||||. .|.||.. .||||||||||||.|.|.|.||.|.|..||..|||||||| kkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnh ECASINRIYGFYDECKRRY--NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKdVQGWGENDRGV |..|.|..||||.|.|..| . .....|...||.||.||..||||.|.||||||.|.|..|||.| ||...|..|||||||||||.. ..||.|.|||. EsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpee-qkgwkpnkRGv SFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADK |.||...| |||.|..||||.|||.|||.||||||.|.|||.|||||||||..|..|...||..|..|....||... gfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskh |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP_Nematode_6.PD | 31-299 | 60 | 4.90000000001e-135 | 438.8 | In-house | 2-271 (272) | Show / Hide |
Range on Protein: 31-299 Range on HMM: 2-271/272 Sequence Identity: 60% (164 aa) TENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI .|.|. |. .....| .|. |.|.|||.|.|||||||| ||||||. |||||..||||||||||||.||||.|.||||||.|.|.|||||||||||..| keeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceai NRIYGFYDECKRRYN-IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA ||.||||||..|||. .|...| ..|| ||..|.| ..|.| |||||. |.|..|.|.. ||.| ... | |||||||.. |.|| || |||| .||. nrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGe EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA ..|.|.|.| |.||..||||||.|||||||...|||.||||.|||.|||| |.|.||| |..||..|||. davkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlkpe |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP4C.PD | 31-297 | 49 | 4.8e-105 | 340.6 | In-house | 2-268 (271) | Show / Hide |
Range on Protein: 31-297 Range on HMM: 2-268/271 Sequence Identity: 49% (132 aa) TENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI .|.|.. || |.|||.. . . ....| .|||||||.||||.||. || || |||||||.||||. |.||. ||||.|..||.. |.|||||. .| keeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqi NRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDkDVQGWGENDRGVSFTFGA ..||||||| |.| ....|. |. |. |..|||.|.|||| ||||||.......|| | | ..||..| |||||||||.|..||. || . ||.. tqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpe-daegwavsprgagylfgs EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILK ||..| .. |..|||||||.| .||.. .....|..|||||| | |.. .||.| |.|.. dvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkife |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP_Nematode_4.PD | 31-299 | 49 | 7.1e-105 | 340.1 | In-house | 2-270 (271) | Show / Hide |
Range on Protein: 31-299 Range on HMM: 2-270/271 Sequence Identity: 49% (132 aa) TENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI |..|| . ....|| .. | |.|||.|. ||.|.|. || |||. | .|| ..|||||||||.|..|.. ||...||.|... .||||||| ||. tkeeiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasv NRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAE |..||||.||. .| ..|| .| ||| |||.|.. .|..| ||||||.| |....| | .| ..|.||| ||||.|||..|..| . ||.|.||| .| nkkygfyeecvtkygeelwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkg VVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA | . .. ..||| |||||| |||| .. |.|.|.||.|||| |||.|.. .||.| |.. | |. vvedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislvalvpe |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP2C.PD | 30-299 | 49 | 2.5e-100 | 325.2 | In-house | 1-270 (271) | Show / Hide |
Range on Protein: 30-299 Range on HMM: 1-270/271 Sequence Identity: 49% (133 aa) LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS |.|.|.. || |..||. . . |...|. .|||.|||..||| || || |..||||.||||||| |.||..||.| |..|.| .|||||| leeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrq INRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDkDVQGWGENDRGVSFTFG | ..||||||| |.| | ..|| ||| |..||..|.||..||| |||||| ......|| . | .|| .| .|||||||||| .||| || .||| itqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpd-drggwgisprgagytfg AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA .. .| .. .| |..||||.| .||.. .|..||.||||||| | .|.. .|..| || .|| kdiseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdpa |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP_Nematode_3.PD | 85-299 | 54 | 7.6e-99 | 320.6 | In-house | 93-307 (308) | Show / Hide |
Range on Protein: 85-299 Range on HMM: 93-307/308 Sequence Identity: 54% (117 aa) SNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME ..||||||||||| |.| . ||.|.|..||.. |||||||| ..|. |||| |.|.||. .|...| ||.||..|.|..||.| |||.| .| ... kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlk QIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMS |. .. ||.|.|| |.|.|| |.|||..|.|. | || .. |||. | .||.|.||||. |||||||||||||| |.|||.||||.|||..||..|..| qldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavls VDETLMCSFQILKPA ||. |..|...|.| vdkklvisltvlrpe |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP_Nematode_5.PD | 34-299 | 48 | 2.8e-96 | 311.6 | In-house | 5-273 (274) | Show / Hide |
Range on Protein: 34-299 Range on HMM: 5-273/274 Sequence Identity: 48% (127 aa) EIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRI .| . | ... . |||.|||..|.||||||. ||||.|. | .|. .||||||||||| .||| . ||...||.||.. |||||||. ||.. dilevlekikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkinkl YGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVP--DQGLLCDLLWSDPDKDVQGWGEND-RGVSFTFGAE |||..| |.... .|.|.| | |. ||. |.|...|.| |||.||.|.|..... . .|||.|| ||||.||.|| .. | |..| || ..| .. ygfkeelkkkrqeslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkk VVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA |.| |.||| |||.|.|.||.|.....|||.|||| |.||| ||.. |...| || ||| evddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpe |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP6C.PD | 30-294 | 46 | 6.4e-96 | 310.6 | In-house | 1-265 (271) | Show / Hide |
Range on Protein: 30-294 Range on HMM: 1-265/271 Sequence Identity: 46% (123 aa) LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS |.|||.. || . ...| . . ...|. .|||||||.|||. || || |...|.||||.|||| ||||. .||. |.|||.. |||||||. lpenelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrq INRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPdKDVQGWGENDRGVSFTFG | ..|||||||...| | . || .|. |. |.||||.||...| |||||||.. ..||| | | ...| .| .|||.||||.||. | .|| . ||. itqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdp-edvetwavsprgagylfg AEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQ .|. .|.| .|.|||||||.||.|.... . .|||..|||||| | ........ ... skvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereak |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP_Nematode_2.PD | 32-297 | 45 | 2.4e-89 | 288.8 | In-house | 3-278 (281) | Show / Hide |
Range on Protein: 32-297
Range on HMM: 3-278/281
Sequence Identity: 45% (126 aa)
ENEIRGLCLKSREIFLSQPILLELEA---PLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECA
..||| .. ... ||... ||... |... .|.|||. ||||.| . |. |.|||||||||||.||.|...|||||| .||. ||||||||
keeiriisnyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedv
SINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKD-VQGWGENDRGVS
|||.|||. .|| | |. . |.||.||.||.. .|..| |||.|| |...|.| .|||. || || ||||||||.| .||. ||.||
nttltygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargis
FTFGAEVVAKFLHKHDLDLICRAHQVVE----DGYEFFAKRQLVTLFSAPNYCGEfDNAGAMMSVDETLMCSFQILK
.|. || || .. ||||. ||||... .|. . |. .||.|||| || . .| ... ..| | ||
fsfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsm-kndssvlkleevktlqfvklk
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| Phosphatase | PPP1CA.AA | Subfamily.PPP3C.PD | 32-290 | 41 | 1.8e-87 | 283.1 | In-house | 3-274 (292) | Show / Hide |
Range on Protein: 32-290 Range on HMM: 3-274/292 Sequence Identity: 41% (111 aa) ENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASIN |... . .. ... ... |||.|||. ..||||||.||||.||| || | ...||||||||||| |.|.. |.| ||.||...||||||||| . eesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhlt RIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDV------QGWGEN-DRGVS . | .|.| .|. .........|..||.||....| .|.||||||...|...|... | ..| .| ||||||||| .|. . .| || |. .. . eyftfkeevkikyseevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrGcs FTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAK------RQLVTLFSAPNYCGEFDNAGAMMSVDETLM |..||.| || | |||.. ..||. . | |.||||||||.. ..| .|.. ... . yfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennvl |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP5C.PD | 40-289 | 45 | 2.6e-84 | 272.9 | In-house | 80-335 (346) | Show / Hide |
Range on Protein: 40-289 Range on HMM: 80-335/346 Sequence Identity: 45% (116 aa) LKSREIFLSQPILLELEAP----LKICGDIHGQYYDLLRLFEYGGFPPES-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIY |.. |.. ..| |.|.. | . .|||||||.|||| .|| | | |. ||| ||.|||| |.|.| .||..|. ||..||| ||||| ..|..| leakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhesdnmnkly GFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKdVQGWGENDRGVSFTFGAEVVA || .|.| .|. |. . ||. || ||.| ...||.. .|||| | | ....|.| | .. |..|||..||||||.. .|.. |||...|| .| | GfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqe-anGrspskrGvgiqfGpdvtk KFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSV-DETL ||.. .|.|| |.|.| |.|||. . .|.|.||||||| . .| ||.... .. | kflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddl |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP_Nematode_7.PD | 31-297 | 38 | 2.9e-72 | 233.1 | In-house | 2-293 (296) | Show / Hide |
Range on Protein: 31-297 Range on HMM: 2-293/296 Sequence Identity: 38% (112 aa) TENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLF----------EYGGFP-PESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFF ..||. |. . | | .. .|.|. .|. | ||||||| || |. . ... .. ..|||||||||..|.| |.|..|.|| ||.... sknellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyi LLRGNHECASINRIYGFYDECKRRY----NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPT-DVPDQGLLCDLLWSDP----- |||||||. .|| |.| | . | .... | ..| .|.||.| |||.| |||.|||.|.|.|..| || .| .. | |||..|| llrGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvql ---DKDVQGWGEN-DRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILK .. . .| ||.|..|. | .. .| .|.|| |||| .|..|||...|.|.||||.| .|.|| ||.. |. | ..|. laavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangklsiaslr |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP7C.PD | 59-291 | 34 | 1.5e-57 | 184.7 | In-house | 70-329 (338) | Show / Hide |
Range on Protein: 59-291 Range on HMM: 70-329/338 Sequence Identity: 34% (89 aa) LKICGDIHGQYYDLLRLFEYGGFPPE-SNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY---NIKLWKTFTD ...|||.||. ||| .. |.| . .|.| ||.|||||.|.| ...|.|. . ||....| ||||| .| ||| | . .| .|. ... | vtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfalllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlled CFNCLPIAAIVDEKIFCCHGGLSP--DLQSMEQIRR-----IMRPT----DVPDQG------------LLCDLLWSDPDKDVQGWGENDRGVSFTFGAEV | ||.|...||||. .|||.| ||. ...| | ...|. . . . . |.||||| ... . || ||..| .|. vfawlplatlidekilivhGGisdktdlelldkiersklvsvlkpprlkeeaesesgeekkltleewrqildilwsdpkaqeGckpntlrGgGsyfGpdv VAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMC |.|..|.|. |.|. .|||| .....|.||| || | | || . . ..|. tkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdltp |
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| Phosphatase | PPP1CA.AA | Metallophos | 57-252 | 28 | 2.5e-44 | 158.37 | Pfam | 1-124 (124) | Show / Hide |
Range on Protein: 57-252 Range on HMM: 1-124/124 Sequence Identity: 28% (56 aa) APLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCF ... .||||||||.||.|||| . . ...|.|||||||..|.|.|.||..||..|| .....||||.....|. |||| | ..| .. ..| MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E-------NDW-MWWWWF NCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVE ..| | ..| ||.|.||.. |. ...|...|.|. |. -WMPLA-LDDWKILCMHGPP----------------------------------------------------------FCK-NGVDYVIRGHTHVP |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP_Nematode_1.PD | 49-298 | 28 | 6.2e-42 | 133.7 | In-house | 19-269 (273) | Show / Hide |
Range on Protein: 49-298 Range on HMM: 19-269/273 Sequence Identity: 28% (72 aa) QPILLE-LEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECK-RRYNI .. ||| .||.....||| ..| |||.... |.|.| .||||. .| || |||.. .|| |. ||.|...|||..|. .. | . | . . | etslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrligelrvrfpds KLWKTFTDCFN----CLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDvQGWGENDrgvsfTFGA-EVVAKFLHKHDL .. . ||.||... |... ..|.|. .. ... . | .. .. .| |. . ||| .. ..| . | |.... nkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiP-sPvtend-----idekskivkellkatdm DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKP |...|| .|| | | .|.||.||... ...| |...|.|| .|. .. svmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfkliek |
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| Phosphatase | PPP1CA.AA | Subfamily.PPP_Nematode_3.PD | 31-83 | 51 | 4.7e-18 | 55.3 | In-house | 2-54 (308) | Show / Hide |
Range on Protein: 31-83 Range on HMM: 2-54/308 Sequence Identity: 51% (27 aa) TENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPP .|.|. ||...||.| ..|. ||||||..|.||||||. ||| |.. |.| kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwpl |
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