PPP1CB
Species: Human
Alias: MGC3672, PPP1CD, PPP1CB, PP-1B
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP1C
Protein domain

Protein domains of PPP1CB.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase PPP1CB.AA Family.PPP.PD 28-304 55 1.1e-136 445.5 In-house 67-345 (349) Show / Hide
Range on Protein: 28-304
Range on HMM: 67-345/349
Sequence Identity: 55% (156 aa)

QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHEC
|....||  |. . .|.. ..|.|||.|||...|||||||..||||||. .|.||.  .||||||||||||.|.|.|.||.|.|..||..|||||||||.
qleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEs

ASINRIYGFYDECKRRF--NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKdVQGWGENDRGVSF
.|.|..||||.|.|...  . .....|...||.||.||..||||.|.||||||.|.|..|||.| ||...|..|||||||||||.. ..||.|.|||.|.
rsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpee-qkgwkpnkRGvgf

TFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKY
||.|.|.|||....||||.|||.|||.||||||.|.|||.|||||||||..|.. ...||..|..|....|||..| .. 
vFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklrl

Phosphatase PPP1CB.AA Subfamily.PPP1C.PD 29-298 88 5.8e-174 566.8 In-house 1-270 (271) Show / Hide
Range on Protein: 29-298
Range on HMM: 1-270/271
Sequence Identity: 88% (240 aa)

MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS
..|||.| || |.|||||||||||||||||||.|||||||.|||||||.||||||.|||||||||||||||||||.||||||||||||||||||||||||
lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas

INRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA
||||||||||||||.||||||||.|||||||.||||||||||.||||||||.|.||||||.|||||||.|||||||||||||.|.|||||||||||||||
inriygfydeckrryniklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfga

DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS
|||.|||..||||||.|||||||||||||||||||||||||||||||||||..|||||.|.||||||||.
dvvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilkpa

Phosphatase PPP1CB.AA PP2Ac 29-299 47 6.6e-167 561.71 SMART 1-321 (321) Show / Hide
Range on Protein: 29-299
Range on HMM: 1-321/321
Sequence Identity: 47% (151 aa)

MTEAEVRGLCIKSREIFLSQPILLELE----APLKICGDIHGQYTDLLRLF---EYGG-FPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
|.. |.. || ...||| ..| ..|.|    .| ..|||||||. ||||||   . .| .||. ||.|||||||||..|.|.||||..|||.||.|||||
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL

RGNHECASIN---RIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSP------DLQSMEQIRRIMR----PTDVPDTGLLCDLLWS
|||||| ..|   ..|||||||||.  . ..|| |..||...|..|... ||.| ||||||      .... ..||.| |    | . || ||.||||||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS

DP--------DKDVQGWGEND-RGVSFTFGADVVSKFLNRHDLDLICRAHQVVE----DGYEFFAKR-----QLVTLFSAPNYCGEFDNAGGMMSV----
||        |..|.||. |  ||.|..||.|||..|.....||||.||||.|.    |||||...|     .|.|.|||||||...||.. .|.|    
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK

------DETLMCSFQILKPSE
      |. |.|.|. .|| .
VIQYKMDKNLKCHFVQFKPQM

Phosphatase PPP1CB.AA Group.PPP.PD 28-304 55 1.1e-136 445.5 In-house 67-345 (349) Show / Hide
Range on Protein: 28-304
Range on HMM: 67-345/349
Sequence Identity: 55% (156 aa)

QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHEC
|....||  |. . .|.. ..|.|||.|||...|||||||..||||||. .|.||.  .||||||||||||.|.|.|.||.|.|..||..|||||||||.
qleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEs

ASINRIYGFYDECKRRF--NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKdVQGWGENDRGVSF
.|.|..||||.|.|...  . .....|...||.||.||..||||.|.||||||.|.|..|||.| ||...|..|||||||||||.. ..|| .|.|||.|
rsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpee-qkgwkpnkRGvgf

TFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKY
.||.|.|.|||....||||.|||.|||.||||||.|.|||.|||||||||..|.. ...||..|..|....|||..| ..
vFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklrl

Phosphatase PPP1CB.AA Subfamily.PPP_Nematode_6.PD 30-298 60 9.69999999999e-135 437.8 In-house 2-271 (272) Show / Hide
Range on Protein: 30-298
Range on HMM: 2-271/272
Sequence Identity: 60% (163 aa)

TEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI
.|.|.  |. .....| .|. |.|.|||.|.||||||||.||||||. |||||.|||||||||||||.||||.|.||||||.|.|.|||||||||||..|
keeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceai

NRIYGFYDECKRRFN-IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA
||.||||||..||..  .|...| ..|| ||..|.| ..|.| |||||. |.|..|.|.. ||.| ... |  |||||||.. |.|| || |||| .||.
nrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGe

DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS
|.| |.|.. |.||..||||||.|||||||...|||.||||.|||.|||| ..|.||| |..||..|||.
davkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlkpe

Phosphatase PPP1CB.AA Subfamily.PPP_Nematode_4.PD 29-297 48 5.5e-104 337.1 In-house 1-269 (271) Show / Hide
Range on Protein: 29-297
Range on HMM: 1-269/271
Sequence Identity: 48% (129 aa)

MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS
.|. |.  .  ....|| ..  | |.|||.|. ||.|.|. || |||.  | .||  ..|||||||||.|..|.. ||...||.|... .||||||| ||
ltkeeiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheias

INRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA
.|..||||.||. .. ..|| .|  ||| |||.|.. .|..| ||||||.| |....| | .|. .| ||| ||||.|||..|..| .  ||.|.||| .
vnkkygfyeecvtkygeelwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgk

DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKP
|| .   . ..||| |||||| |||| .. |.|.|.||.||||| ||. .. .||.|  |.. | |   
gvvedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislvalvp

Phosphatase PPP1CB.AA Subfamily.PPP4C.PD 30-296 49 3.8e-103 334.4 In-house 2-268 (271) Show / Hide
Range on Protein: 30-296
Range on HMM: 2-268/271
Sequence Identity: 49% (131 aa)

TEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI
.| ||. || |.|||.. .  . ....|  .|||||||. |||.||. ||  || |||||||.||||. |.||. ||||.|..||..  |.|||||. .|
keeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqi

NRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDkDVQGWGENDRGVSFTFGA
 ..||||||| |.. ....|.  |. |. |..|||.|.|||| ||||||.......|| | | ..||. | |||||||||.|..||.   ||  . ||.|
tqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpe-daegwavsprgagylfgs

DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILK
||..| .. |..|||||||.| .||..  .....|..||||||    |   .. .||.|   |.|.. 
dvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkife

Phosphatase PPP1CB.AA Subfamily.PPP2C.PD 30-298 48 6e-98 317.3 In-house 2-270 (271) Show / Hide
Range on Protein: 30-298
Range on HMM: 2-270/271
Sequence Identity: 48% (131 aa)

TEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI
.|.||. || |..||.  .  . |...|. .|||.|||. ||| ||  ||  |..||||.|||||||  |.||..||.| |..|.|   .||||||   |
eeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqi

NRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDkDVQGWGENDRGVSFTFGA
 ..||||||| |.. | ..|| ||| |..||..|.||..||| |||||| ......|| . |  .||  | .|||||||||| .|||   ||  .||| |
tqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpd-drggwgisprgagytfgk

DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS
.  .| .. .| |..||||.| .||..  .|..||.|||||||    | .... .|..|  ||   .|. 
diseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdpa

Phosphatase PPP1CB.AA Subfamily.PPP_Nematode_3.PD 84-298 53 8e-98 317.3 In-house 93-307 (308) Show / Hide
Range on Protein: 84-298
Range on HMM: 93-307/308
Sequence Identity: 53% (114 aa)

ANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME
.|||||||||||  |.| . ||.|.|..||.. ||||||||  ..|. |||| |.|.|.. .|...|   ||.||..|.|..||.| |||.| .| ...|
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlk

QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMS
. .. ||.|.|| |.|.|| |.|||..|.|. |  || .. |||. | .||...||||. |||||||||||||| |.|||.||||.|||..||.. ..||
qldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavls

VDETLMCSFQILKPS
|. |..|...|.|. 
vdkklvisltvlrpe

Phosphatase PPP1CB.AA Subfamily.PPP_Nematode_5.PD 40-298 47 4.2e-96 311.0 In-house 12-273 (274) Show / Hide
Range on Protein: 40-298
Range on HMM: 12-273/274
Sequence Identity: 47% (123 aa)

KSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDEC
| ...    . |||.|||..|.||||||. ||||.|.  | .|. .||||||||||| .||| . ||...||.||..  |||||||.  ||..|||..| 
kikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkinklygfkeel

KRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDT--GLLCDLLWSDPDKDVQGWGEND-RGVSFTFGADVVSKFLN
|.... .|.|.| | |. ||. |.|...|.| |||.||.|.|..... . .||   .   ||||||.||.|| ..   |  |..|  ||  .| ..|.. 
kkkrqeslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllk

RHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS
|.||| |||.|.|.||.|.....|||.|||| |.||  | | ..|...|  ||  |||    
kldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpe

Phosphatase PPP1CB.AA Subfamily.PPP6C.PD 30-293 44 2.8e-92 298.6 In-house 2-265 (271) Show / Hide
Range on Protein: 30-293
Range on HMM: 2-265/271
Sequence Identity: 44% (118 aa)

TEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI
.|.|.. || .  ...| .  .  ...|. .|||||||. ||. ||  ||  |...|.||||.||||  ||||. .||. |.|||..  |||||||.  |
penelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqi

NRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPdKDVQGWGENDRGVSFTFGA
 ..|||||||.... | . || .|. |. |.||||.||...| |||||||.. ..||| | | ...|  | .|||.|||| .||. |   .||  . ||.
tqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdp-edvetwavsprgagylfgs

DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQ
 |...|..  .|.|||||||.||.|.... . .|||..||||||    |   .......   ...
kvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereak

Phosphatase PPP1CB.AA Subfamily.PPP_Nematode_2.PD 32-296 45 8.9e-88 283.7 In-house 4-278 (281) Show / Hide
Range on Protein: 32-296
Range on HMM: 4-278/281
Sequence Identity: 45% (123 aa)

AEVRGLCIKSREIFLSQPILLELEA---PLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS
|.| ..  ... ||... ||...    |... .|.|||..||||.|   . |.  .|||||||||||.||.|...||||||.||.  ||||||||     
eeiriisnyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvn

INRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKD-VQGWGENDRGVSF
  |||.|||. ..|    | |. . |.||.||.||.. .|..| |||.|| |...|.| .|||. ||  || ||||||||.|   .||.   ||.||.|.
ttltygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisf

TFGADVVSKFLNRHDLDLICRAHQVVE----DGYEFFAKRQLVTLFSAPNYCGEfDNAGGMMSVDETLMCSFQILK
  || || .  ||||. ||||...    .|. . |. .||.|||| || .  .|   .. ..|     |  ||   
sfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsm-kndssvlkleevktlqfvklk

Phosphatase PPP1CB.AA Subfamily.PPP3C.PD 31-289 40 3.1e-85 275.8 In-house 3-274 (292) Show / Hide
Range on Protein: 31-289
Range on HMM: 3-274/292
Sequence Identity: 40% (107 aa)

EAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASIN
|...  .  .. ... ... |||.|||. ..||||||. |||.||| || | ...|||||||||||  |.|..  |.| ||.||...|||||||||  . 
eesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhlt

RIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDV------QGWGEN-DRGVS
  . | .|.| ... .........|..||.||....| .|.||||||...|...|... |  ..| .| ||||||||| .|. . .|  || |. ..   
eyftfkeevkikyseevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrGcs

FTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAK------RQLVTLFSAPNYCGEFDNAGGMMSVDETLM
|..||.. ||  | |||.. ..||. . |        |.||||||||.. ..| . .. ...  .       
yfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennvl

Phosphatase PPP1CB.AA Subfamily.PPP5C.PD 39-288 44 5.7e-82 265.2 In-house 80-335 (346) Show / Hide
Range on Protein: 39-288
Range on HMM: 80-335/346
Sequence Identity: 44% (113 aa)

IKSREIFLSQPILLELEAP----LKICGDIHGQYTDLLRLFEYGGFPPEA-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIY
... |.. ..| |.|.. |    . .|||||||. ||| .||  | | |   ||| ||.||||  |.|.| .||..|. ||..||| |||||  ..|..|
leakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhesdnmnkly

GFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKdVQGWGENDRGVSFTFGADVVS
|| .|.| ... |. . ||. || ||.| ...||.. .|||| | |   ....|.| | .. |. |||..||||||..  .|..  |||...|| || .|
GfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqe-anGrspskrGvgiqfGpdvtk

KFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV-DETL
||.  .|.|| |.|.| |.|||.  . .|.|.||||||| . .| |..... .. | 
kflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddl

Phosphatase PPP1CB.AA Subfamily.PPP_Nematode_7.PD 31-296 37 2.1e-71 230.3 In-house 3-293 (296) Show / Hide
Range on Protein: 31-296
Range on HMM: 3-293/296
Sequence Identity: 37% (109 aa)

EAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLF----------EYGGFP-PEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
. |.  |. .  | | .. .|.|. .|. | |||||||.|| |.           .  ...  .  ..|||||||||..|.||.|..|.|| ||....||
knellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyil

LRGNHECASINRIYGFYDECKRRFNI----KLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPT-DVPDTGLLCDLLWSDP------
|||||. .||  |.|  | . |..     .... | ..|  .|.||.| |||.| |||.|| |.|.|.|..| ||  .| .  |  |||..||       
lrGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqll

--DKDVQGWGEN-DRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILK
  ..   . .|  ||.|..|.   |... .. .|.|| |||| .|..|||...|.|.||||.| .|.|| | .. |.     | ..|.   
aavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangklsiaslr

Phosphatase PPP1CB.AA Metallophos 56-251 28 4.6e-44 157.49 Pfam 1-124 (124) Show / Hide
Range on Protein: 56-251
Range on HMM: 1-124/124
Sequence Identity: 28% (56 aa)

APLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCF
... .|||||||| ||.|||| .   .  ...|.|||||||..|.|.|.||..||..|| .....||||.....|. |||| |       ..| .. ..|
MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E-------NDW-MWWWWF

NCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVE
 ..| | ..| ||.|.||..                                                          |.  ...|...|.|. |.
-WMPLA-LDDWKILCMHGPP----------------------------------------------------------FCK-NGVDYVIRGHTHVP

Phosphatase PPP1CB.AA Subfamily.PPP_Nematode_1.PD 48-296 29 2e-41 132.0 In-house 19-268 (273) Show / Hide
Range on Protein: 48-296
Range on HMM: 19-268/273
Sequence Identity: 29% (73 aa)

QPILLE-LEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NI
.. ||| .||.....||| ..|.|||....  |.|.|  .||||. .| || |||.. .||  |. ||.|...|||..|.     .. | . || . . |
etslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrligelrvrfpds

KLWKTFTDCFN----CLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDvQGWGENDrgvsfTFG-ADVVSKFLNRHDL
..   .       ||.||... |... ..|.|. ..  ...  . |     .     .. .| |.  .   |||      .. . .| . |   |.... 
nkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiP-sPvtend-----idekskivkellkatdm

DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILK
|...|| .|| |  | .|.||.||...  ...| | ..|.||  .|. ..      
svmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfklie

Phosphatase PPP1CB.AA Subfamily.PPP7C.PD 57-190 41 6.4e-39 123.5 In-house 69-205 (338) Show / Hide
Range on Protein: 57-190
Range on HMM: 69-205/338
Sequence Identity: 41% (55 aa)

PLKICGDIHGQYTDLLRLFEYGGFPP-EANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF---NIKLWKTFT
...|||.||.  ||| ..   |.|  | .|.| ||.|||||.|.| ...|.|. . ||....| |||||   .|  |||  | . ... |. ... | | 
evtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfalllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlle

DCFNCLPIAAIVDEKIFCCHGGLSpDLQSMEQIRRIMR
 ||.|...||||. .|||.| |  ..| . .| |    
dvfawlplatlidekilivhGGis-dktdlelldkier

Phosphatase PPP1CB.AA Subfamily.PPP7C.PD 200-289 35 3.3e-21 65.2 In-house 239-328 (338) Show / Hide
Range on Protein: 200-289
Range on HMM: 239-328/338
Sequence Identity: 35% (32 aa)

LCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLM
. |.||||| ..   . .  ||    ||.|| .|.|....|.|. |.|.   .||||  .....|.||| ||  |  | |  . . ..|.
ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdlt

Phosphatase PPP1CB.AA Subfamily.PPP_Nematode_3.PD 30-81 51 9.4e-18 54.3 In-house 2-53 (308) Show / Hide
Range on Protein: 30-81
Range on HMM: 2-53/308
Sequence Identity: 51% (27 aa)

TEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFP
.|.|.  || ..||.| ..|. ||||||..|.||||||. ||| |..  |.|
kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwp

Sequence
Name Sequence Type Origin Length Description Download
PPP1CB.AA Protein None 327 None Fasta, JSON
PPP1CB.NA RNA None 981 None Fasta, JSON
PPP1CB.AA.PD_29-299 Protein Phosphatase Domain None 271 None Fasta, JSON