Gene PPP1CB
PPP1CB
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPP1CB.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPP1CB.AA | Family.PPP.PD | 28-304 | 55 | 1.1e-136 | 445.5 | In-house | 67-345 (349) | Show / Hide |
Range on Protein: 28-304 Range on HMM: 67-345/349 Sequence Identity: 55% (156 aa) QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHEC |....|| |. . .|.. ..|.|||.|||...|||||||..||||||. .|.||. .||||||||||||.|.|.|.||.|.|..||..|||||||||. qleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEs ASINRIYGFYDECKRRF--NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKdVQGWGENDRGVSF .|.|..||||.|.|... . .....|...||.||.||..||||.|.||||||.|.|..|||.| ||...|..|||||||||||.. ..||.|.|||.|. rsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpee-qkgwkpnkRGvgf TFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKY ||.|.|.|||....||||.|||.|||.||||||.|.|||.|||||||||..|.. ...||..|..|....|||..| .. vFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklrl |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP1C.PD | 29-298 | 88 | 5.8e-174 | 566.8 | In-house | 1-270 (271) | Show / Hide |
Range on Protein: 29-298 Range on HMM: 1-270/271 Sequence Identity: 88% (240 aa) MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS ..|||.| || |.|||||||||||||||||||.|||||||.|||||||.||||||.|||||||||||||||||||.|||||||||||||||||||||||| lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas INRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA ||||||||||||||.||||||||.|||||||.||||||||||.||||||||.|.||||||.|||||||.|||||||||||||.|.||||||||||||||| inriygfydeckrryniklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfga DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS |||.|||..||||||.|||||||||||||||||||||||||||||||||||..|||||.|.||||||||. dvvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilkpa |
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| Phosphatase | PPP1CB.AA | PP2Ac | 29-299 | 47 | 6.6e-167 | 561.71 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 29-299
Range on HMM: 1-321/321
Sequence Identity: 47% (151 aa)
MTEAEVRGLCIKSREIFLSQPILLELE----APLKICGDIHGQYTDLLRLF---EYGG-FPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
|.. |.. || ...||| ..| ..|.| .| ..|||||||. |||||| . .| .||. ||.|||||||||..|.|.||||..|||.||.|||||
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL
RGNHECASIN---RIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSP------DLQSMEQIRRIMR----PTDVPDTGLLCDLLWS
|||||| ..| ..|||||||||. . ..|| |..||...|..|... ||.| |||||| .... ..||.| | | . || ||.||||||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS
DP--------DKDVQGWGEND-RGVSFTFGADVVSKFLNRHDLDLICRAHQVVE----DGYEFFAKR-----QLVTLFSAPNYCGEFDNAGGMMSV----
|| |..|.||. | ||.|..||.|||..|.....||||.||||.|. |||||...| .|.|.|||||||...||.. .|.|
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK
------DETLMCSFQILKPSE
|. |.|.|. .|| .
VIQYKMDKNLKCHFVQFKPQM
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| Phosphatase | PPP1CB.AA | Group.PPP.PD | 28-304 | 55 | 1.1e-136 | 445.5 | In-house | 67-345 (349) | Show / Hide |
Range on Protein: 28-304 Range on HMM: 67-345/349 Sequence Identity: 55% (156 aa) QMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEA-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHEC |....|| |. . .|.. ..|.|||.|||...|||||||..||||||. .|.||. .||||||||||||.|.|.|.||.|.|..||..|||||||||. qleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEs ASINRIYGFYDECKRRF--NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKdVQGWGENDRGVSF .|.|..||||.|.|... . .....|...||.||.||..||||.|.||||||.|.|..|||.| ||...|..|||||||||||.. ..|| .|.|||.| rsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpee-qkgwkpnkRGvgf TFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKY .||.|.|.|||....||||.|||.|||.||||||.|.|||.|||||||||..|.. ...||..|..|....|||..| .. vFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklrl |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP_Nematode_6.PD | 30-298 | 60 | 9.69999999999e-135 | 437.8 | In-house | 2-271 (272) | Show / Hide |
Range on Protein: 30-298 Range on HMM: 2-271/272 Sequence Identity: 60% (163 aa) TEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI .|.|. |. .....| .|. |.|.|||.|.||||||||.||||||. |||||.|||||||||||||.||||.|.||||||.|.|.|||||||||||..| keeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceai NRIYGFYDECKRRFN-IKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA ||.||||||..||.. .|...| ..|| ||..|.| ..|.| |||||. |.|..|.|.. ||.| ... | |||||||.. |.|| || |||| .||. nrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGe DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS |.| |.|.. |.||..||||||.|||||||...|||.||||.|||.|||| ..|.||| |..||..|||. davkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlkpe |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP_Nematode_4.PD | 29-297 | 48 | 5.5e-104 | 337.1 | In-house | 1-269 (271) | Show / Hide |
Range on Protein: 29-297 Range on HMM: 1-269/271 Sequence Identity: 48% (129 aa) MTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS .|. |. . ....|| .. | |.|||.|. ||.|.|. || |||. | .|| ..|||||||||.|..|.. ||...||.|... .||||||| || ltkeeiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheias INRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA .|..||||.||. .. ..|| .| ||| |||.|.. .|..| ||||||.| |....| | .|. .| ||| ||||.|||..|..| . ||.|.||| . vnkkygfyeecvtkygeelwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgk DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKP || . . ..||| |||||| |||| .. |.|.|.||.||||| ||. .. .||.| |.. | | gvvedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislvalvp |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP4C.PD | 30-296 | 49 | 3.8e-103 | 334.4 | In-house | 2-268 (271) | Show / Hide |
Range on Protein: 30-296 Range on HMM: 2-268/271 Sequence Identity: 49% (131 aa) TEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI .| ||. || |.|||.. . . ....| .|||||||. |||.||. || || |||||||.||||. |.||. ||||.|..||.. |.|||||. .| keeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqi NRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDkDVQGWGENDRGVSFTFGA ..||||||| |.. ....|. |. |. |..|||.|.|||| ||||||.......|| | | ..||. | |||||||||.|..||. || . ||.| tqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpe-daegwavsprgagylfgs DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILK ||..| .. |..|||||||.| .||.. .....|..|||||| | .. .||.| |.|.. dvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkife |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP2C.PD | 30-298 | 48 | 6e-98 | 317.3 | In-house | 2-270 (271) | Show / Hide |
Range on Protein: 30-298 Range on HMM: 2-270/271 Sequence Identity: 48% (131 aa) TEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI .|.||. || |..||. . . |...|. .|||.|||. ||| || || |..||||.||||||| |.||..||.| |..|.| .|||||| | eeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqi NRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDkDVQGWGENDRGVSFTFGA ..||||||| |.. | ..|| ||| |..||..|.||..||| |||||| ......|| . | .|| | .|||||||||| .||| || .||| | tqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpd-drggwgisprgagytfgk DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS . .| .. .| |..||||.| .||.. .|..||.||||||| | .... .|..| || .|. diseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdpa |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP_Nematode_3.PD | 84-298 | 53 | 8e-98 | 317.3 | In-house | 93-307 (308) | Show / Hide |
Range on Protein: 84-298 Range on HMM: 93-307/308 Sequence Identity: 53% (114 aa) ANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME .||||||||||| |.| . ||.|.|..||.. |||||||| ..|. |||| |.|.|.. .|...| ||.||..|.|..||.| |||.| .| ...| kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldlk QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMS . .. ||.|.|| |.|.|| |.|||..|.|. | || .. |||. | .||...||||. |||||||||||||| |.|||.||||.|||..||.. ..|| qldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavls VDETLMCSFQILKPS |. |..|...|.|. vdkklvisltvlrpe |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP_Nematode_5.PD | 40-298 | 47 | 4.2e-96 | 311.0 | In-house | 12-273 (274) | Show / Hide |
Range on Protein: 40-298 Range on HMM: 12-273/274 Sequence Identity: 47% (123 aa) KSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDEC | ... . |||.|||..|.||||||. ||||.|. | .|. .||||||||||| .||| . ||...||.||.. |||||||. ||..|||..| kikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkinklygfkeel KRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDT--GLLCDLLWSDPDKDVQGWGEND-RGVSFTFGADVVSKFLN |.... .|.|.| | |. ||. |.|...|.| |||.||.|.|..... . .|| . ||||||.||.|| .. | |..| || .| ..|.. kkkrqeslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllk RHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPS |.||| |||.|.|.||.|.....|||.|||| |.|| | | ..|...| || ||| kldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkpe |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP6C.PD | 30-293 | 44 | 2.8e-92 | 298.6 | In-house | 2-265 (271) | Show / Hide |
Range on Protein: 30-293 Range on HMM: 2-265/271 Sequence Identity: 44% (118 aa) TEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASI .|.|.. || . ...| . . ...|. .|||||||. ||. || || |...|.||||.|||| ||||. .||. |.|||.. |||||||. | penelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqi NRIYGFYDECKRRF-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPdKDVQGWGENDRGVSFTFGA ..|||||||.... | . || .|. |. |.||||.||...| |||||||.. ..||| | | ...| | .|||.|||| .||. | .|| . ||. tqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdp-edvetwavsprgagylfgs DVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQ |...|.. .|.|||||||.||.|.... . .|||..|||||| | ....... ... kvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereak |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP_Nematode_2.PD | 32-296 | 45 | 8.9e-88 | 283.7 | In-house | 4-278 (281) | Show / Hide |
Range on Protein: 32-296 Range on HMM: 4-278/281 Sequence Identity: 45% (123 aa) AEVRGLCIKSREIFLSQPILLELEA---PLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECAS |.| .. ... ||... ||... |... .|.|||..||||.| . |. .|||||||||||.||.|...||||||.||. |||||||| eeiriisnyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvn INRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKD-VQGWGENDRGVSF |||.|||. ..| | |. . |.||.||.||.. .|..| |||.|| |...|.| .|||. || || ||||||||.| .||. ||.||.|. ttltygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisf TFGADVVSKFLNRHDLDLICRAHQVVE----DGYEFFAKRQLVTLFSAPNYCGEfDNAGGMMSVDETLMCSFQILK || || . ||||. ||||... .|. . |. .||.|||| || . .| .. ..| | || sfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsm-kndssvlkleevktlqfvklk |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP3C.PD | 31-289 | 40 | 3.1e-85 | 275.8 | In-house | 3-274 (292) | Show / Hide |
Range on Protein: 31-289 Range on HMM: 3-274/292 Sequence Identity: 40% (107 aa) EAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASIN |... . .. ... ... |||.|||. ..||||||. |||.||| || | ...||||||||||| |.|.. |.| ||.||...||||||||| . eesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhlt RIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDV------QGWGEN-DRGVS . | .|.| ... .........|..||.||....| .|.||||||...|...|... | ..| .| ||||||||| .|. . .| || |. .. eyftfkeevkikyseevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrGcs FTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAK------RQLVTLFSAPNYCGEFDNAGGMMSVDETLM |..||.. || | |||.. ..||. . | |.||||||||.. ..| . .. ... . yfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennvl |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP5C.PD | 39-288 | 44 | 5.7e-82 | 265.2 | In-house | 80-335 (346) | Show / Hide |
Range on Protein: 39-288 Range on HMM: 80-335/346 Sequence Identity: 44% (113 aa) IKSREIFLSQPILLELEAP----LKICGDIHGQYTDLLRLFEYGGFPPEA-NYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIY ... |.. ..| |.|.. | . .|||||||. ||| .|| | | | ||| ||.|||| |.|.| .||..|. ||..||| ||||| ..|..| leakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhesdnmnkly GFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKdVQGWGENDRGVSFTFGADVVS || .|.| ... |. . ||. || ||.| ...||.. .|||| | | ....|.| | .. |. |||..||||||.. .|.. |||...|| || .| GfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqe-anGrspskrGvgiqfGpdvtk KFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSV-DETL ||. .|.|| |.|.| |.|||. . .|.|.||||||| . .| |..... .. | kflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddl |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP_Nematode_7.PD | 31-296 | 37 | 2.1e-71 | 230.3 | In-house | 3-293 (296) | Show / Hide |
Range on Protein: 31-296 Range on HMM: 3-293/296 Sequence Identity: 37% (109 aa) EAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLF----------EYGGFP-PEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL . |. |. . | | .. .|.|. .|. | |||||||.|| |. . ... . ..|||||||||..|.||.|..|.|| ||....|| knellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyil LRGNHECASINRIYGFYDECKRRFNI----KLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPT-DVPDTGLLCDLLWSDP------ |||||. .|| |.| | . |.. .... | ..| .|.||.| |||.| |||.|| |.|.|.|..| || .| . | |||..|| lrGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqll --DKDVQGWGEN-DRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILK .. . .| ||.|..|. |... .. .|.|| |||| .|..|||...|.|.||||.| .|.|| | .. |. | ..|. aavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangklsiaslr |
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| Phosphatase | PPP1CB.AA | Metallophos | 56-251 | 28 | 4.6e-44 | 157.49 | Pfam | 1-124 (124) | Show / Hide |
Range on Protein: 56-251 Range on HMM: 1-124/124 Sequence Identity: 28% (56 aa) APLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCF ... .|||||||| ||.|||| . . ...|.|||||||..|.|.|.||..||..|| .....||||.....|. |||| | ..| .. ..| MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E-------NDW-MWWWWF NCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVE ..| | ..| ||.|.||.. |. ...|...|.|. |. -WMPLA-LDDWKILCMHGPP----------------------------------------------------------FCK-NGVDYVIRGHTHVP |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP_Nematode_1.PD | 48-296 | 29 | 2e-41 | 132.0 | In-house | 19-268 (273) | Show / Hide |
Range on Protein: 48-296 Range on HMM: 19-268/273 Sequence Identity: 29% (73 aa) QPILLE-LEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NI .. ||| .||.....||| ..|.|||.... |.|.| .||||. .| || |||.. .|| |. ||.|...|||..|. .. | . || . . | etslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrligelrvrfpds KLWKTFTDCFN----CLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDvQGWGENDrgvsfTFG-ADVVSKFLNRHDL .. . ||.||... |... ..|.|. .. ... . | . .. .| |. . ||| .. . .| . | |.... nkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiP-sPvtend-----idekskivkellkatdm DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILK |...|| .|| | | .|.||.||... ...| | ..|.|| .|. .. svmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfklie |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP7C.PD | 57-190 | 41 | 6.4e-39 | 123.5 | In-house | 69-205 (338) | Show / Hide |
Range on Protein: 57-190 Range on HMM: 69-205/338 Sequence Identity: 41% (55 aa) PLKICGDIHGQYTDLLRLFEYGGFPP-EANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF---NIKLWKTFT ...|||.||. ||| .. |.| | .|.| ||.|||||.|.| ...|.|. . ||....| ||||| .| ||| | . ... |. ... | | evtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfalllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlle DCFNCLPIAAIVDEKIFCCHGGLSpDLQSMEQIRRIMR ||.|...||||. .|||.| | ..| . .| | dvfawlplatlidekilivhGGis-dktdlelldkier |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP7C.PD | 200-289 | 35 | 3.3e-21 | 65.2 | In-house | 239-328 (338) | Show / Hide |
Range on Protein: 200-289 Range on HMM: 239-328/338 Sequence Identity: 35% (32 aa) LCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLM . |.||||| .. . . || ||.|| .|.|....|.|. |.|. .|||| .....|.||| || | | | . . ..|. ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdlt |
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| Phosphatase | PPP1CB.AA | Subfamily.PPP_Nematode_3.PD | 30-81 | 51 | 9.4e-18 | 54.3 | In-house | 2-53 (308) | Show / Hide |
Range on Protein: 30-81 Range on HMM: 2-53/308 Sequence Identity: 51% (27 aa) TEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFP .|.|. || ..||.| ..|. ||||||..|.||||||. ||| |.. |.| kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnGwp |
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