PPP2CB
Species: Human
Alias: PP2CB, PPP2CB
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP2C
Protein domain

Protein domains of PPP2CB.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase PPP2CB.AA Subfamily.PPP5C.PD 4-290 39 1.7e-86 280.1 In-house 50-343 (346) Show / Hide
Range on Protein: 4-290
Range on HMM: 50-343/346
Sequence Identity: 39% (117 aa)

KAFTKE-LDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCP----VTVCGDVHGQFHDLMELFRIGGK-SPDTNYLFMGDYVDRGYYSVETV
.  ||| ... .|.... |.|..  . ..  .|||.| |.. . |.. |    .|||||.||||.||...|.. |. |..  ||| ||.|||| .|||..
ekitkefvkellelfkkqkklhkkyalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsvevi

TLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYgNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSI-DTLDHIRALDRLQEVPHEGPMC
 .|...|. ||... . |||||| .. ..||| .|.  || ...| . ||..|..|||. ... ... .||||  .   |||..| .|| .. |.||...
ltllgfkllypnhfflsrGnhesdnmnklyGfegevkaky-tekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglll

DLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMEL-DDTLKYSFLQFD
.||||||... | . | || | .|| |... | . |.|.|. |.|.. .|||.  || ...|.||||||| .||..|...| .| ||  | .|. 
ellwsdpqeanGrspskrGvgiqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkfktfe

Phosphatase PPP2CB.AA Subfamily.PPP2C.PD 23-293 92 5.4e-189 615.9 In-house 1-271 (271) Show / Hide
Range on Protein: 23-293
Range on HMM: 1-271/271
Sequence Identity: 92% (252 aa)

LNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQ
|.|..|..|||||||||.|||||.||.||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||.||||||||||||||
leeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrq

ITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQ
||||||||||||||||||||||||||||||||||||||.|||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||.
itqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpddrggwgisprgagytfgk

DISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP
||||.||..|||||||||||||||||||.||||||||||||||||||||||||.||||.||||||||||||
diseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdpap

Phosphatase PPP2CB.AA PP2Ac 23-293 44 1.5e-158 533.96 SMART 1-321 (321) Show / Hide
Range on Protein: 23-293
Range on HMM: 1-321/321
Sequence Identity: 44% (142 aa)

LNENQVRTLCEKAKEILTKESNVQEVR----CPVTVCGDVHGQFHDLMELF---RIGG-KSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITIL
.... .. ||...|||. .|.|. ||      |||||||.||||.||..||   ...|  .|.|||.|.|||||||..|.|...||...|..||.....|
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL

RGNHESRQIT---QVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSP------SIDTLDHIRALDR----LQEVPHEGPMCDLLWS
|||||.|...   |.||||||| |||.....||.|...|...||.||....|.| ||||||      .| ||| || .||     || |..|.|||||||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS

DP---------DDRGGWGISP-RGAGYTFGQDISETFNHANGLTLVSRAHQLVM----EGYNWCHDR-----NVVTIFSAPNYCYRCGNQAAIMEL----
||         ..  ||.... ||..|.||.|. . | ..|.| |. ||||.|.    .|| ..|||      ..|||||||||..|.| ||.|..    
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK

------DDTLKYSFLQFDPAP
      |. || .| ||.|..
VIQYKMDKNLKCHFVQFKPQM

Phosphatase PPP2CB.AA Subfamily.PPP4C.PD 24-292 69 1.3e-146 476.9 In-house 2-270 (271) Show / Hide
Range on Protein: 24-292
Range on HMM: 2-270/271
Sequence Identity: 69% (185 aa)

NENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQI
.|..|..||.||.||| .|||||.| .|||||||.||||.||.|||..||. |.|||||.||.||||.|||||  ||.|||||||.|||..|||||||||
keeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqi

TQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQD
|||||||||||||||.|.||.| |..||||.|.|..||.|||.||||||||.|||.||..|| ||||||||.||||||||.|||..||||||| ||.|..
tqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgsd

ISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPA
|.||.||...|..||||||||||..  ...|.|..||||||||||| |||.|||..|.. |  |. |  
vveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaa

Phosphatase PPP2CB.AA Subfamily.PPP6C.PD 23-289 60 1.3e-134 437.4 In-house 1-267 (271) Show / Hide
Range on Protein: 23-289
Range on HMM: 1-267/271
Sequence Identity: 60% (161 aa)

LNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQ
|.||... ||.. ...| .||||| |..|||||||.||||.||.|||| ||. |||.|.|.||.|||||||.||.|.|..||..||.|||.|||||||||
lpenelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrq

ITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQ
||||||||||||.||||||.|||.|..|| |...|..|.|..|.|||||| . |||.|| ..| ||.||.|..|||.||||.|   | .||||||| ||.
itqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgs

DISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQF
 ... |.| | | |..||||||.||...  | ..||..||||||||||| |.|..|.|. . ..  |
kvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereaklf

Phosphatase PPP2CB.AA Family.PPP.PD 6-294 50 1.1e-133 435.7 In-house 51-341 (349) Show / Hide
Range on Protein: 6-294
Range on HMM: 51-341/349
Sequence Identity: 50% (146 aa)

FTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDT-NYLFMGDYVDRGYYSVETVTLLVALK
..  .. ||...| |||....| .|.|.|||.| ||.|..|| .|.|||||.||||.||..||.|.|. |.. .|||.|||||||..|||...||.|||.
tpdlvkelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalk

VRYPERITILRGNHESRQITQVYGFYDECLRKYGN-ANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDP
.||.|...||||||||....|||||.|. .|| . ......|...|..|||.||.|..|.|.||||||.. .||.||...| .|.|.||..||||||||.
llypsrffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdp

DDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR
.. ||  ..||.|..||.|. | | . |.| |. |||..|.|||.....|..||||||||||....|.||....|..||.|. ||.|... 
eeqkgwkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskh

Phosphatase PPP2CB.AA Group.PPP.PD 6-294 50 1.1e-133 435.7 In-house 51-341 (349) Show / Hide
Range on Protein: 6-294
Range on HMM: 51-341/349
Sequence Identity: 50% (146 aa)

FTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDT-NYLFMGDYVDRGYYSVETVTLLVALK
..  .. ||...| |||....| .|.|.|||.| ||.|..|| .|.|||||.||||.||..||.|.|. |.. .|||.|||||||..|||...||.|||.
tpdlvkelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalk

VRYPERITILRGNHESRQITQVYGFYDECLRKYGN-ANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDP
.||.|...||||||||....|||||.|. .|| . ......|...|..|||.||.|..|.|.||||||.. .||.||...| .|.|.||..||||||||.
llypsrffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdp

DDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR
.. ||  ..||.|..||.|. | | . |.| |. |||..|.|||.....|..||||||||||....|.||....|..||.|. ||.|... 
eeqkgwkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskh

Phosphatase PPP2CB.AA Subfamily.PPP1C.PD 23-290 49 1.8e-104 339.0 In-house 1-268 (271) Show / Hide
Range on Protein: 23-290
Range on HMM: 1-268/271
Sequence Identity: 49% (133 aa)

LNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQ
|.|...|.||.||.||. ..  . |...|. ..||.|||..||. ||  ||  |..||||.|||||||  |.||..||.|.|..|||.. .||||||. .
lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas

ITQVYGFYDECLRKYgNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDR-GGWGISPRGAGYTFG
|...||||||| |.| | ..|| |.| |. ||..|.|| .|||.||||||.. .|..|| . |  .||..| .|||||||||..  ||| . ||  .|||
inriygfydeckrry-niklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfg

QDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFD
.|. |.| . . | |. ||||.| .||.. ..|..||.||||||| .  | .|.| .|..|  ||  ..
advvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilk

Phosphatase PPP2CB.AA Subfamily.PPP_Nematode_6.PD 24-290 46 2.3e-98 318.5 In-house 2-269 (272) Show / Hide
Range on Protein: 24-290
Range on HMM: 2-269/272
Sequence Identity: 46% (122 aa)

NENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQI
.|... .|.|.||....|.. . ||  |..||||.|||. ||. ||  ||  ||.||||.||||||| .|.|...||.| ||..|... .||||||  .|
keeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceai

TQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDD-RGGWGISPRGAGYTFGQ
 .|||||||. |.| ...... | ..|..||||||| |.|.|.|||||... .||..|.| | .. ..|    |||||||..   ||  . ||....||.
nrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGe

DISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFD
|  . . .   . || ||||.| .||..  ....|||||||.|| .| ||.|..|. |. ||  .   
davkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlk

Phosphatase PPP2CB.AA Subfamily.PPP_Nematode_4.PD 27-292 40 2.4e-86 279.3 In-house 5-270 (271) Show / Hide
Range on Protein: 27-292
Range on HMM: 5-270/271
Sequence Identity: 40% (108 aa)

QVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQV
.. ..  .|..|...|... |.  |. | ||.|.||.||..|| . |. |.. ..|.|||||||  ..|.. ||..||.||..|| .||||||  .. ..
eiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnkk

YGFYDECLRKYGNaNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRG-GWGISPRGAGYTFGQDIS
||||.||  |||. ..|  |   |. ||..||.  ...|.||||||.. .||..|   .  | .. | . ||||.|||... .|  | ||..||||... 
ygfyeecvtkyge-elwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgvv

ETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPA
|   .  .. |. ||||.|..||.    |...|.||.||||    |||.. ||..|. |. .. |. 
edvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislvalvpe

Phosphatase PPP2CB.AA Subfamily.PPP3C.PD 23-280 42 3.8e-85 275.5 In-house 1-271 (292) Show / Hide
Range on Protein: 23-280
Range on HMM: 1-271/292
Sequence Identity: 42% (116 aa)

LNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQ
|.|...  . |.| ..| ||... ||  |.||.||.||||.||..|| .|||  .|.|||.||||||||.|.|.|  | |||. ||.|. .||||||.|.
leeesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrh

ITQVYGFYDECLRKYGNaNVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGW--------GISPR
.|. . | .|.  ||.. .|.. ... || |||.||.... .|.|||||| |..|| |..|||..|.|. ||.||||||||.. |           |.||
lteyftfkeevkikyse-evyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvr

GAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHD------RNVVTIFSAPNYCYRCGNQAAIMELDD
  | ..   . .| . | |  . |||.   .||.  ..        ..|.||||||.    |.||...... 
GcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyen

Phosphatase PPP2CB.AA Subfamily.PPP_Nematode_5.PD 24-291 37 4.5e-77 248.6 In-house 2-272 (274) Show / Hide
Range on Protein: 24-291
Range on HMM: 2-272/274
Sequence Identity: 37% (100 aa)

NENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQI
..... .. ||.|..|   . . ||. |.|..||.|||..||. .|   |..|...|||.|||||||  |.| . || .||..||... .|||||| ..|
sdkdilevlekikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkki

TQVYGFYDECLRKYGnANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE--VPHEGPMCDLLWSDPDDRgGWGIS---PRGAGY
 ..|||..|  .|..  ...| | |.| .||| | |. .|.|.|||.|| ...|| ..|| . ..|| . ||||.||.     ..     |.    ||. 
nklygfkeelkkkrq-eslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekd-aktfelnkiraisv

TFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDP
  . . .  .. |. |||... |||..  |. .||.|||||. .  | .|.. ....|. || .. |      
vfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlkp

Phosphatase PPP2CB.AA Subfamily.PPP_Nematode_2.PD 27-282 42 3.8e-76 245.5 In-house 5-270 (281) Show / Hide
Range on Protein: 27-282
Range on HMM: 5-270/281
Sequence Identity: 42% (110 aa)

QVRTLCEKAKEILTKESNVQEV---RCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQI
..| ... ||. ... | . .|     |||| .|.|||. ||. .| | .  . ..|||.|||||||  |||.| ||.|.|.||. . .||||||  . |
eiriisnyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvnt

TQVYGFYDECLRKYGN--ANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPD--DRGGWGISPRGAGYT
  |||.|||| ||..    ||... | |..|||.||. ....|.|||.|| .. |. |  ..|||  |  ||||||||.  .| ||..| ||  ..|.. 
tltygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisfs

FGQDISETFNHANGLTLVSRAHQLVME----GYNWCHDRNVVTIFSAPNYCyRCGNQAAIMELDDTL
. | | . |.| || |||||. |    |. .  .  .|..||| ||    .|..... |.       
fddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnyl-smkndssvlkleevk

Phosphatase PPP2CB.AA Subfamily.PPP_Nematode_3.PD 77-291 44 7e-74 238.6 In-house 92-306 (308) Show / Hide
Range on Protein: 77-291
Range on HMM: 92-306/308
Sequence Identity: 44% (96 aa)

DTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYgNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDT
.|||.||||||| .|.| |.||.|||..||.....|||||||| . . |||| |. ..| .|.... |   |  |||.|.|. .|.|.|||.| ..  |.
ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkry-saalyeafqlafnvlplcavvnkkilcmhGGiseelld

LDHIRALDRLQEVPHEGPMCDLLWSDPDDR-GGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAI
 . .|.|  ..|  | ..|| |.||| .  |.  |.||||  ||..  . |..   | || ||||.|..||..  ||..|||||||.|| .  | ||...
lkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav

MELDDTLKYSFLQFDP
.|. |. |.  . |  
lsvdkklvisltvlrp

Phosphatase PPP2CB.AA Subfamily.PPP_Nematode_7.PD 25-285 34 1.4e-60 194.8 In-house 3-288 (296) Show / Hide
Range on Protein: 25-285
Range on HMM: 3-288/296
Sequence Identity: 34% (97 aa)

ENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELF----------RIGGKS-PDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITI
.|.. .|....|| . || .. |.  |||. ||.|||..||. .           .. . |   . ..|.|||||||..|.|..|..|||. ||... .|
knellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyil

LRGNHESRQITQVYGFYDE---CLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDR-LQEVPHEGPMCDLLWSDPDDRGGW
|||||.. |   |.|  |    | |    .... | . | ..||.|||  .|.|.|||.|| ...|..|. ..| |.|| ..    |||..|| |  .  
lrGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqll

GISPRGAGYTFGQ--DISETFNHA--------NGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYS
.. . . |.. .  ..| .||.|        ..| |. |||| .||...  |. ..||||||.|    .|. |.....   | |  
aavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangkls

Phosphatase PPP2CB.AA Metallophos 50-245 27 2.1e-41 148.65 Pfam 1-124 (124) Show / Hide
Range on Protein: 50-245
Range on HMM: 1-124/124
Sequence Identity: 27% (53 aa)

CPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDL
 ....|||.|||..||..||.|. . ......|.|||||||..| |.. ||...|..|| .. ..||||........|||| |        |.| .. ..
MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E--------NDW-MWWWW

FDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVM
| ..||  |.|. |.| ||..                                                         |   ||. .| |.|. |.
F-WMPLA-LDDWKILCMHGPP---------------------------------------------------------FCK-NGVDYVIRGHTHVP

Phosphatase PPP2CB.AA Subfamily.PPP7C.PD 8-185 34 2e-40 128.4 In-house 22-205 (338) Show / Hide
Range on Protein: 8-185
Range on HMM: 22-205/338
Sequence Identity: 34% (63 aa)

KELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRC----PVTVCGDVHGQFHDLME-LFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVA
..... .|.... |.|  . | ..  ..|..| .  |...|       ||||||.||...||.  |.. |  |.. .|.| ||.||||  ||| . .|.|
ddveklleafklkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfa

LKVRYPERITILRGNHESRQITQVYGFYDECLRKY--GNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDtLDHIRALDR
| . ||. . . |||||   .   |||  |   ||   .... . . |.| .|||..|.| .|. .|||.| . | |. ...|  
lllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdktd-lelldkier

Phosphatase PPP2CB.AA Subfamily.PPP_Nematode_1.PD 30-287 23 8e-35 110.3 In-house 8-265 (273) Show / Hide
Range on Protein: 30-287
Range on HMM: 8-265/273
Sequence Identity: 23% (60 aa)

TLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGF
| |.| .|. . | .. .  .|||.||. ... ||...... |  ..  .||.|. .| | .|.|.. .|.  |. ||...||||..|   .     .. 
elledalkiaeetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrl

YDECLRKYGNANVWKYF----TDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRggwgiSPRGAGYTFGQ-DI
|   .. ..| |.        |   ||. |... .......|.|. |   ... |..| ...    .. . | |       ||   .  ...  |     
igelrvrfpdsnkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiP-----sPvtendidekski

SETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFL
 |  .... |....| |||  . . ...|..||...|. ... .|  || .|           
vkellkatdmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfk

Phosphatase PPP2CB.AA Subfamily.PPP7C.PD 195-289 36 2.9e-22 68.7 In-house 239-334 (338) Show / Hide
Range on Protein: 195-289
Range on HMM: 239-334/338
Sequence Identity: 36% (34 aa)

MCDLLWSDPDDR-GGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQF
. |.|||||  . | .  . ||.|  || |... . .  .|.|. |.|.  .|||...|...|.||||| ||     |. | . | ..|...|.  
ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdltprivqy

Phosphatase PPP2CB.AA Subfamily.PPP_Nematode_3.PD 24-73 42 3e-13 39.5 In-house 2-51 (308) Show / Hide
Range on Protein: 24-73
Range on HMM: 2-51/308
Sequence Identity: 42% (21 aa)

NENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGG
.|...  || .|.|.. ||    |...|||..||.||||.||. |. . |
kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG

Sequence
Name Sequence Type Origin Length Description Download
PPP2CB.AA Protein None 309 None Fasta, JSON
PPP2CB.NA RNA None 927 None Fasta, JSON
PPP2CB.AA.PD_23-293 Protein Phosphatase Domain None 271 None Fasta, JSON