Gene PPP3CA
PPP3CA
Species: Human
Alias: PPP2B, CCN1, CNA1, CALNA1, CALNA, CALN, PPP3CA
External Links:
COSMIC
,
Entrez Gene
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPP3CA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPP3CA.AA | Family.PPP.PD | 47-347 | 48 | 3.7e-124 | 404.3 | In-house | 59-349 (349) | Show / Hide |
Range on Protein: 47-347
Range on HMM: 59-349/349
Sequence Identity: 48% (143 aa)
KAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSP-ANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLF
.. .. .||.. .|... | . .|..|.|||...||.|||||||||| ||..||...| | |...|||||||||||.||.|..|.|.|||.|||. .|||
veafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrff
LLRGNHECRHLTEYFTFKQECKIKY--SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPledfgnEK
|||||.|.......|..|.| || .|..|......|..||||||.....||||||||||...||.|||..|..||| |..||.||||||. |... .|
llRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdp------ee
tQEHFTHNTvRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAPNYLDVYNNKAAVLKYENNV-MNIRQFNCSPHPYW
. ||..... . ||..||..||| | |||| ...||..... . |.||||||||.. |.|||||||...|. ..|.||..|.|...|....
-qkgwkpnk-RGvgfvFgpdavekflkknnldliiRahevveeGyeffanrk------lvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklr
LPNFM
lkedk
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| Phosphatase | PPP3CA.AA | Subfamily.PPP3C.PD | 56-347 | 79 | 5e-178 | 580.4 | In-house | 1-292 (292) | Show / Hide |
Range on Protein: 56-347 Range on HMM: 1-292/292 Sequence Identity: 79% (233 aa) LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRH |||..||.||.|.|..|..|..||...||.||.|||||||.||.|||||||.||.|.|||||||||||||||||||||.|||| ||..|||||||||||| leeesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrh LTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRG ||||||||.|.||||||.||.|.|..||.||||||.||.||||||||||||..||||.||||||||||.||.||.||||||||.|.|.|.|.|..|.||| lteyftfkeevkikyseevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrG CSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFM ||||||| |||||||.|.||||.||||||||||||||||..||||||||.|||||||||||||||||||||||.|||.||||.||||||||| csyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennvlnirkfncsehpywlpnfm |
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| Phosphatase | PPP3CA.AA | PP2Ac | 56-347 | 42 | 1.4e-164 | 554.01 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 56-347 Range on HMM: 1-321/321 Sequence Identity: 42% (136 aa) LEESVALRIITEGASILRQEKNLLDID----APVTVCGDIHGQFFDLMKLF---EVGG-SPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLL . ........ | . |.|||.|.. .. .||||||||||||.||. || ...| |..|.|.|||||||||..||||...|...||.||. ||| MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL RGNHECRHLT---EYFTFKQECKIKY-SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSP------EINTLDDIRKLDR----FKEPPAYGPMCDILWS |||||||| . .|. |..|||.|| ..|... ....|...||.||.|...||.|||||| .|.||||||..|| ..||| |.|||.||| RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS DP--LEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQD----AGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKY--E || ...|...........|..||.||.. ...|.||...||| | |||.... ||... ...|. .. ||||||||||.| ..|.|||.|. . DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTR-VHKLITIFSAPNYCDQCDNHAAVMKVNDH NNVMNIRQFNCSPHPYWLPNFM ........ |...|.... ..| KVIQYKMDKNLKCHFVQFKPQM |
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| Phosphatase | PPP3CA.AA | Group.PPP.PD | 47-347 | 48 | 3.7e-124 | 404.3 | In-house | 59-349 (349) | Show / Hide |
Range on Protein: 47-347
Range on HMM: 59-349/349
Sequence Identity: 48% (143 aa)
KAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSP-ANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLF
.. .. .||.. .|... | . .|..|.|||...||.|||||||||| ||..||...| | |...|||||||||||.||.|..|.|.|||.|||..||||
veafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrff
LLRGNHECRHLTEYFTFKQECKIKY--SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPledfgnEK
||||.|.......|..|.| || .|..|......|..||||||.....||||||||||...||.|||..|..||| |..||.||||||. |... .|.
llRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdp------ee
tQEHFTHNTvRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAPNYLDVYNNKAAVLKYENNV-MNIRQFNCSPHPYW
||..... . ||..||..||| | |||| ...||..... . |.||||||||.. |.|||||||...|. ..|.||..|.|...|....
-qkgwkpnk-RGvgfvFgpdavekflkknnldliiRahevveeGyeffanrk------lvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhklr
LPNFM
lkedk
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| Phosphatase | PPP3CA.AA | Subfamily.PPP4C.PD | 62-328 | 44 | 8.9e-85 | 274.1 | In-house | 7-260 (271) | Show / Hide |
Range on Protein: 62-328 Range on HMM: 7-260/271 Sequence Identity: 44% (115 aa) LRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFT .. .. || .| |. .|.||||||||||||.||..||.|||. .|.||||||.||||..|.|. | | |||. ||. . |.|||||.|..|. . | kalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqitqvyg FKQECKIKY-SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEdfgnekTQeHFtHNTVRGCSYFY .|| || | .|. |.. || |.|||..... .||||||||.|.|||.|| .|| .| | ||.||.||||| ... . . || |.. .| . fydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdped------ae-gw-avsprgagylf SYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAPNYLDVYNNKAAVLKYENNV | ..|.. | |||. ||... . . ..|..||||| |.||.|...... gsdvveqfneandielicrahqlvmegyklhfnek------vltvwsapnycyrcgnvaaileldeel |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP1C.PD | 61-330 | 40 | 1.7e-83 | 270.1 | In-house | 6-262 (271) | Show / Hide |
Range on Protein: 61-330 Range on HMM: 6-262/271 Sequence Identity: 40% (108 aa) ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYF ..... |. .. ||...||. ..||||||. ||..||| || |....||||||||||| |.| .. | |.|| ||...||||||||| ... ...| irklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecasinriy TFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPledfgnEKTQEHFTHNTvRGCSYFY .||| .|. ... . .|.|.|||.||..... .||||||||....|..||.. | . | | .||.||||| .|. .....| || |. .. gfydeckrryniklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdp------dkevkgwgend-rgvsftf SYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAPNYLDVYNNKAAVLKYENNVMN | .||....| |.|||. . ||... | | |.|.|||||| . ..| .||.. ..... gadvvekflkkhdldlivrahqvvedgyeffakrq------lvtlfsapnycgefdnagavmsvdeellc |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP5C.PD | 48-335 | 39 | 3.5e-79 | 256.0 | In-house | 62-343 (346) | Show / Hide |
Range on Protein: 48-335 Range on HMM: 62-343/346 Sequence Identity: 39% (116 aa) AHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGDIHGQFFDLMKLFEVGGSPANT-RYLFLGDYVDRGYFSIECVLYLWALKILYPK .. |. .|.. .||.|..| ..|... |..|. | .||||||||||.||. .||. |.|... ||| ||.|||| ||.|..| |...|.|||. elfkkqkklhkkyalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypn TLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLS-PEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGN .|| ||||| .. . . |..|.| ||.|.|.| . |. |||| ..|...| ||||| . ||||.||.||...|||.....||||| | | .. hfflsrGnhesdnmnklyGfegevkakytekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqeanGr EKTQehfthntvRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAPNYLDVYNNKAAVLKYENNVM--NIRQFN . || . . .||..||| |.|.|| .. ||.. .. . |||.|||||| |.||.|... ... . ....|. spsk--------rGvgiqfGpdvtkkflkennleliirshevkeeGyevehdGk------litvfsapnycdqmgnkgafitlrgddlkpkfktfe |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP2C.PD | 62-335 | 44 | 3.9e-79 | 255.6 | In-house | 7-268 (271) | Show / Hide |
Range on Protein: 62-335 Range on HMM: 7-268/271 Sequence Identity: 44% (119 aa) LRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFT ... . ||..|.|. .. .|||||||.||||.||..|| .||. .| |||.||||||||.|.|.| .| |||. |.. . .||||||| .|. . | kklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqitqvyg FKQECKIKYSE-RVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGnektqehFtHNTVRGCSYFY .|| ||.. |. | ||.|||.||...| .|.||||||.|.|||.||.|||..| | |||||.||||| . |. . ||. | . || fydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpddrgg-------w-gisprgagytf SYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSqttgfpSLITIFSAPNYLDVYNNKAAVLKYENNVM-NIRQFN ..|.| . |||. || . ..|||||||| |.||.|. .... ..||. gkdiseefnktngltlvsrahqlvmegynwshdr------nvvtifsapnycyrcgnqaailelddelkysflqfd |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP_Nematode_6.PD | 62-329 | 39 | 2.4e-76 | 246.3 | In-house | 7-262 (272) | Show / Hide |
Range on Protein: 62-329 Range on HMM: 7-262/272 Sequence Identity: 39% (103 aa) LRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFT |..... ......| |....||..||||||||. ||..||. || | .. ||||||||||| .|.| .| | | |. .|..||||||||| .. . . | lkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceainrvyG FKQECKIKYS-ERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPledfgnEKTQEHFTHNTvRGCSYFY ..|.. .|. .|.| | ..|. |||.||. .. ||.|||||.....||..|.| | ...|.||||| |.... ...|. || |. . || . fydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdp------enavkgwaens-rGvsvvf SYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAPNYLDVYNNKAAVLKYENNVM .|.. .. . |||. || .. . . |.||||||.|.. ..| |||.| ..... GedavkkllekldidlvarahqvvqdGyeffaekk------lvtifsaphycgqfdnaaavmkvdeklv |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP6C.PD | 67-328 | 42 | 1.6e-74 | 240.4 | In-house | 12-260 (271) | Show / Hide |
Range on Protein: 67-328 Range on HMM: 12-260/271 Sequence Identity: 42% (111 aa) EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQEC . .| .| |. . .||||||||||||.||..|| ||. .|.|.||||.|||||.|.| . .| .||. ||. . |||||||.|..|. . | .||. lvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqitqvygfydec KIKYSE-RVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPlEDFgnektqEHFtHNTVRGCSYFYSYPAV || . .. |.. || |..||....| |||||||||...|||.|| ..| .| | |..||..|||| || |.. . . || |.. . | lnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdp-edv------etw-avsprgagylfgskvt CEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAPNYLDVYNNKAAVLKYENNV |.. ||| | |||. . |.. . . . |.|..||||| | |..|. |.. kefvhinnlklicrahqlveeglkymfdek------lvtvwsapnycyrcgniasilaledae |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP_Nematode_4.PD | 63-328 | 38 | 3.2e-70 | 226.4 | In-house | 8-260 (271) | Show / Hide |
Range on Protein: 63-328 Range on HMM: 8-260/271 Sequence Identity: 38% (102 aa) RIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTF .| | .|. .||.| .|.||. | ||.|.|| ||..||.. | . .....||||||||| .||... |..||| |.. ..||||||| .. . | svireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnkkygf KQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPledfgNEKTQEHFThnTVRGCSYFYSY .||. || | .. .|. ||..||. .. ||.|||||||. .||..| . |.. |. |.||.|| ..|..| .. ..|| || . yeecvtkygeelwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadp-----dnkveewka--sirgisytfgk PAVCEFLQHNNLLSILRAHEAQDAGYRMYrksqtTGfPSLITIFSAPNYLDVYNNKAAVLKYENNV | . .. .. |.|||. || . .| |||.||.||| . ..| ||||| ..|. gvvedvckslevdliirahqvvqdgyevl-----sg-rklitvfsvpnycaqfknaaavlkldenl |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP_Nematode_5.PD | 62-326 | 38 | 7.2e-68 | 218.4 | In-house | 7-261 (274) | Show / Hide |
Range on Protein: 62-326 Range on HMM: 7-261/274 Sequence Identity: 38% (102 aa) LRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFT | .. . |.|. ||...||.|..||||||. ||...|. | .....||||||||||| |.| .|.|..|||.|||. |||||||.... . . | levlekikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkinklyg FKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAY--GPMCDILWSDPledfgnEKTQEHFTHNTVRGCSYF |.| | |..|..| | | ||| | .... ||.|||.||....||... | . . | || . |.||.|| || .. | | .|. | . fkeelkkkrqeslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadp------ekdaktfelnkiraisvv YSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAPNYLDVYNNKAAVLKYEN | ..|.. .. |.|||| .. || .. . . |.|.|||| | | .||.. .. fGkkevddllkkldidlivrahevseeGyaflfdkr------lvtvfsapyysgedtnlgavvvvsk |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP_Nematode_2.PD | 71-327 | 42 | 5e-67 | 215.6 | In-house | 16-269 (281) | Show / Hide |
Range on Protein: 71-327 Range on HMM: 16-269/281 Sequence Identity: 42% (112 aa) ILRQEKNLLDIDA---PVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECK . . ||..| |||| .|.|||. ||...| . ..|....||||||||||| |.| || | |.| |||. ||||||||| | . | .||. aflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvnttltygffdecl IKYS---ERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPledfgnEKTQEHFTHNTVRGCSYFYSYPA ||. |.|. .|||..||||||. .. ||.|||.|| .. |.|| |..| |.|| ||.||||| |||.. . || |. . .| ekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdp------ektervgwslsargisfsfddiv VCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGfpSLITIFSAPNYLDVYNNkAAVLKYENN .| ..|.| ..|||. . .| | . .| |...||| ||| |. ..||| |. vekfcadndldlvvrahqlskemirqghklrang--rlvslfsalnylsmknd-ssvlkleev |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP_Nematode_7.PD | 63-328 | 35 | 1.9e-63 | 204.2 | In-house | 8-285 (296) | Show / Hide |
Range on Protein: 63-328 Range on HMM: 8-285/296 Sequence Identity: 35% (98 aa) RIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLF-----------EVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNH .| . ...||.|..| .|||. ||||||. ||... .. | .....|||||||||. ||||. .|||||||. ..|||||||. slidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyillrGnh ECRHLTEYFTFKQECK----IKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAY-GPMCDILWSDP--LEDFGNEKT . . |..| . . ....|. ..| .|||||. .. ||||||.|| ...|.||....| . . |.|..|| . ... etkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqllaavse QEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAPNYLDVYNNKAAVLKYENNV ....|.||| |. . || .. ...|| |.|||. .|..... . |.||||||.| . .|. |||| | | kpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkk------Lltifsaprymnesdnsgavlkveang |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP_Nematode_3.PD | 110-329 | 40 | 9e-58 | 185.8 | In-house | 92-298 (308) | Show / Hide |
Range on Protein: 110-329 Range on HMM: 92-298/308 Sequence Identity: 40% (89 aa) NTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTL . .||||||||||| |||| |. | |||.|||. .|||||||| | . . | .|.| .||...|.| || .|||.|..|.. ||.|||.| |. | ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGiseelldl DDIRKLDRFKEPPAYGPMCDILWSDPledfgnEKTQEHFtHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAP . . ||.| . | | ..|. |.|| ... ... ... || . . .|| |||.. .| ..|||. || .. . |.|||||| kqldklkrpldipdvGvladltwadp------daevkgy-kesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrk------lvtifsap NYLDVYNNKAAVLKYENNVM .| .| ||||. ..... sycGqldniaavlsvdkklv |
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| Phosphatase | PPP3CA.AA | Metallophos | 83-285 | 23 | 3.7e-36 | 131.26 | Pfam | 1-124 (124) | Show / Hide |
Range on Protein: 83-285 Range on HMM: 1-124/124 Sequence Identity: 23% (47 aa) APVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAF .....|||||||. ||..|||.. . .. ..|.|||||||. |.||...|...|..||. ...||||...|..... |. | ... .... | MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E-------NDW-MWWWWF DCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHE ..||| | . .||.||.. |.. |.. ..|.|. -WMPLA-LDDWKILCMHGPP-----------------------------------------------------------------FCK-NGVDYVIRGHT AQD .. HVP |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP7C.PD | 52-219 | 36 | 4.6e-35 | 110.8 | In-house | 33-207 (338) | Show / Hide |
Range on Protein: 52-219 Range on HMM: 33-207/338 Sequence Identity: 36% (64 aa) KEGRLEESVALRIITEGASILRQEKNLLDIDA----PVTVCGDIHGQFFDLMKLFEVGGSPAN-TRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFL .. | | |. | . .|.| .|. . . ||||||.||.. ||. .. | |.. |.| ||.|||| |.| .| | ||..||| ..| lkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfalllvypkevyl LRGNHECRHLTEYFTFKQECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSpEINTLDDIRKLDRFK ||||| | . | .| . || .... | | ||||.|.... | ||||.| .. |. . |..| | nrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGis-dktdlelldkiersk |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP_Nematode_1.PD | 65-212 | 31 | 1.2e-28 | 90.1 | In-house | 9-162 (273) | Show / Hide |
Range on Protein: 65-212 Range on HMM: 9-162/273 Sequence Identity: 31% (48 aa) ITEGASILRQEKNLLD-IDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFK . | | . .| ||. |.|.|||.||| ... ||...... | | . ..||||. .| | .| | .| | |. ||| ...|||..| . .. lledalkiaeetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrli QECKIKYSE----RVYDACMDA-FDCLPLAALMNQQFLCVHGGLSPEINTLDDI | .... . | .|.. ||.||..|.. |.|..|.|. | ... gelrvrfpdsnkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknv |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP7C.PD | 226-329 | 32 | 3.7e-14 | 42.0 | In-house | 238-328 (338) | Show / Hide |
Range on Protein: 226-329 Range on HMM: 238-328/338 Sequence Identity: 32% (33 aa) PMCDILWSDPledfgneKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQttgfpsLITIFSAPNYLDVYNNKAAVLKYE . ||||||| |.|| . ||.|| .. ..||. || ..|.|| . || . ... ..||||| || ..|. | .| ... qildilwsdp-------kaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkk------vltifsasnyyeeGsnrGayvklg NNVM . kdlt |
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| Phosphatase | PPP3CA.AA | Subfamily.PPP_Nematode_3.PD | 72-109 | 48 | 8.9e-11 | 31.4 | In-house | 17-54 (308) | Show / Hide |
Range on Protein: 72-109 Range on HMM: 17-54/308 Sequence Identity: 48% (18 aa) LRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPA . .|. |...||||..||||||| ||. |... | | fwkeplkleleapvtivGdihGqfedllalldlnGwpl |
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