Gene PPP4C
PPP4C
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPP4C.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPP4C.AA | Subfamily.PPP7C.PD | 5-184 | 36 | 6e-38 | 120.3 | In-house | 22-207 (338) | Show / Hide |
Range on Protein: 5-184 Range on HMM: 22-207/338 Sequence Identity: 36% (67 aa) SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDS----PVTVCGDIHGQFYDLKE-LFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLA .|... .|... .|.. | . .....|.. |..|| . ||||||.||.. || |.. | .| .|.| ||||||| ||| |.|.| ddveklleafklkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfa LKVRYPDRITLIRGNHESRQITQVYGFYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSiQTLDQIRTIDRKQ | . || . | ||||| . ||| | || . . | ..| .| |...|| ||. ||||.| . |. .|.|.. lllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdk-tdlelldkiersk |
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| Phosphatase | PPP4C.AA | Subfamily.PPP4C.PD | 20-290 | 90 | 2.7e-176 | 574.2 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 20-290 Range on HMM: 1-271/271 Sequence Identity: 90% (245 aa) IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ |||.|||||||||||||||||||||||||||||||||||||||.|||.||||||||||||.||||||||||||||||||||||||||||||||||||||| ikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrq ITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGS |||||||||||||||||..|||||||.||||||.||||||||||||||||||.|||.||.|||||||||.||.||||||||||..||.|||||||||||| itqvygfydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgs DVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAP |||.|||.||||..|||||||||||||.||||.|||||||||||||||||||||||||.|.||| |||||. dvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaaa |
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| Phosphatase | PPP4C.AA | PP2Ac | 20-290 | 41 | 2.4e-149 | 503.38 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 20-290
Range on HMM: 1-321/321
Sequence Identity: 41% (134 aa)
IKESEVKALCAKAREILVEESNVQRVD----SPVTVCGDIHGQFYDLKELF---RVGG-DVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLI
. ..|...|| ...||. |.|. .|. .||||||||||||.|| .|| ...| .|.|||.|.||.||||..|.|. .||...|..||....|
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL
RGNHESRQIT---QVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSP------SIQTLDQIRTIDR----KQEVPHDGPMCDLLWS
|||||.|... |.||||||| |||... .| ...| |....|.|.|..||.|.|||||| .|.|||.|| ||| || |..|.|||||||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS
DP---------EDTTGWGVSP-RGAGYLFGSDVVAQFNAANDIDMICRAHQLVM----EGYKWHFNE-----TVLTVWSAPNYCYRCGNVAAILEL----
|| .. ||. .. ||..| || ||| .| .|..|.|.||||.|. .||.. ... ..|..||||||..|.| ||....
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK
------DEHLQKDFIIFEAAP
|. |. |. |....
VIQYKMDKNLKCHFVQFKPQM
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| Phosphatase | PPP4C.AA | Subfamily.PPP2C.PD | 21-290 | 69 | 7e-149 | 484.4 | In-house | 2-271 (271) | Show / Hide |
Range on Protein: 21-290 Range on HMM: 2-271/271 Sequence Identity: 69% (186 aa) KESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI .|.|||.|| ||.||| .||||. | |||||||.||||.|| ||||.||..|.||||||||.||||.||||| ||.||||||..|||..||||||||| eeeevkklcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqi TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSD |||||||||||||||. .||.| |..|||| |.|..|..|||.||||||||.|||.||..|| |||||.|||||||||||.|.|||.||||||| || |. tqvygfydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpddrggwgisprgagytfgkd VVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAP .|| .|.. ...||||||||||.| .. |.|..||||||||||| |||||||..|.. |. |. || iseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdpap |
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| Phosphatase | PPP4C.AA | Subfamily.PPP6C.PD | 21-290 | 66 | 3.7e-147 | 478.6 | In-house | 2-271 (271) | Show / Hide |
Range on Protein: 21-290 Range on HMM: 2-271/271 Sequence Identity: 66% (177 aa) KESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI .|.|.|.||.. ..|.|||||| | ||||||||||||||||.|||| ||.||.|.|.|.|||||||.||.||| .||.||..|||||||.||||||||| penelkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqi TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSD |||||||||||.|||....|.|||..|| |...||||....|||||||| ..||||||.|.| ||.||.|..|||.||||||| |||||||||||| |. tqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgsk VVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAP .|.. |....||||||||.||.|..|.| . ||||||||||||||.|.||.|... .... .|.| | vtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereaklfkavp |
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| Phosphatase | PPP4C.AA | Family.PPP.PD | 8-293 | 47 | 1.2e-129 | 422.4 | In-house | 56-343 (349) | Show / Hide |
Range on Protein: 8-293 Range on HMM: 56-343/349 Sequence Identity: 47% (135 aa) DRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPET-NYLFMGDFVDRGFYSVETFLLLLALKVRYPD .. .|.... . ....||..|. .|.|.| .|.|...|..|.||||||||||.|| .||...| |.. .|||.||.|||| .|||..|||.|||..||. kelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllyps RITLIRGNHESRQITQVYGFYDECLRKYGS-VTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG |..|.|||||||....|||||.|. .|| . .......|.|..|.|.|.||.||.||||||||....|||||.|.|..|.|..|..|||||||||.. | rffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkg WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQET | ..||.|..||.|.| .| |..|.|.|||..|.|||....|. ..|..||||||....| ||.|..|..|. .. .|...... wkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhkl |
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| Phosphatase | PPP4C.AA | Group.PPP.PD | 8-293 | 47 | 1.2e-129 | 422.4 | In-house | 56-343 (349) | Show / Hide |
Range on Protein: 8-293 Range on HMM: 56-343/349 Sequence Identity: 47% (135 aa) DRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPET-NYLFMGDFVDRGFYSVETFLLLLALKVRYPD .. .|.... . ....||..|. .|.|.| .|.|...|..|.||||||||||.|| .||...| |.. .|||.||.|||| .|||..|||.|||..||. kelveafkekkqleakevlelleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllyps RITLIRGNHESRQITQVYGFYDECLRKYGS-VTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG |..|.|||||||....|||||.|. .|| . .......|.|..|.|.|.||.||.||||||||....|||||.|.|..|.|..|..|||||||||.. | rffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkg WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQET | ..||.|..||.|.| .| |..|.|.|||..|.|||....|. ..|..||||||....| ||.|..|..|. .. .|...... wkpnkRGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhkl |
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| Phosphatase | PPP4C.AA | Subfamily.PPP1C.PD | 20-287 | 48 | 1.8e-102 | 332.4 | In-house | 1-268 (271) | Show / Hide |
Range on Protein: 20-287 Range on HMM: 1-268/271 Sequence Identity: 48% (130 aa) IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ .||.|...|| |||||.... . ....|. ..||||||..|| || || ||.||||.||.|||| |.|| .||||.|..||... |.|||||. . lkeaeirklclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas ITQVYGFYDECLRKYgSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPE-DTTGWGVSPRGAGYLFG |...||||||| |.| .. .|. ...|. | ..||.| |||||||||||....|.||| | | .||..| .||||||||....||| . || . ||. inriygfydeckrry-niklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfg SDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFE |||..| . .|.|.|.||||.| .||.. . ..|..|||||| . |..|.. .||.| | |.. advvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdeellcsfqilk |
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| Phosphatase | PPP4C.AA | Subfamily.PPP_Nematode_6.PD | 20-287 | 43 | 3.3e-93 | 301.6 | In-house | 1-269 (272) | Show / Hide |
Range on Protein: 20-287 Range on HMM: 1-269/272 Sequence Identity: 43% (117 aa) IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ |||.|.. |...|.... ... . |..|..||||||||. || || || |..||||.||.|||| .|.|. ||||| ||..|... |.||||| . ikeeellkllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnhecea ITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPED-TTGWGVSPRGAGYLFG | .|||||||. |.| |.... |.|..| |.|.. |.|.|.|||||.....|||.|.. |.. ... ||||||||. ..|| . ||... ||. inrvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfG SDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFE |.|... |||...||||.| .||.. . ..|..|||.||. | ||....||.|. | ... edavkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvdeklvvsfevlk |
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| Phosphatase | PPP4C.AA | Subfamily.PPP_Nematode_4.PD | 23-286 | 42 | 1.1e-85 | 277.2 | In-house | 4-267 (271) | Show / Hide |
Range on Protein: 23-286 Range on HMM: 4-267/271 Sequence Identity: 42% (110 aa) SEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQ |.... .|..|...|... ...|. | ||.|.|| ||..|| . | |||. ..|.||.|||| ..|...||..||.||.||| |.||||| .. .. eeiisvireaeaifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnk VYGFYDECLRKYGsVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPED-TTGWGVSPRGAGYLFGSDV ||||.|| ||| . .| . |. | .||.| |..|.||||||.. .||..| | . |.. | . ||||.||.. . .| | ||..|.|| .|| kygfyeecvtkyg-eelwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgv VAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIF . ..|.| ||||.|..||. ..||.|.||||| ||.| ||| |. ... . vedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenleislval |
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| Phosphatase | PPP4C.AA | Subfamily.PPP5C.PD | 24-289 | 41 | 3e-83 | 269.4 | In-house | 74-345 (346) | Show / Hide |
Range on Protein: 24-289 Range on HMM: 74-345/346 Sequence Identity: 41% (113 aa) EVKALCAKAREILVEESNVQRVD----SPVTVCGDIHGQFYDLKELFRVGGDVPET-NYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESR . .. .| |.| ... . .. . .||||||||||||| ..|.. | . |. ||| ||||||| .|||. |.||..|. ||...| |||||| .. yalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhesd QITQVYGFYDECLRKYGSvTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSP-SIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLF ..||| .|. || . .| ||.|..| |. .|. |.. ||||| |||..|.||| .. |..|....||||||....| . | || | || nmnklyGfegevkakyte-kvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqeanGrspskrGvgiqf GSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILEL-DEHLQKDFIIFEAA || .| |....| |.|.. .|||. . . ..||.|||||| . || .|...| ...|. | ||| GpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkfktfeav |
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| Phosphatase | PPP4C.AA | Subfamily.PPP3C.PD | 21-278 | 42 | 3.9e-83 | 268.9 | In-house | 2-272 (292) | Show / Hide |
Range on Protein: 21-278 Range on HMM: 2-272/292 Sequence Identity: 42% (114 aa) KESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI .|... . .| ..| .|... .|..|.||.|||||||||| .|| |||. .|.|||.||.|||| .|.|. | |.|||. ||.|. |.|||||.|.. eeesalkiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhl TQVYGFYDECLRKYGsVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGW--------GVSPRG |. . | .|. ||. .|. ..| || | |.|....| .|||||||| |..||.|...|| .|.|. ||.|||||||| .| |.|| teyftfkeevkikys-eevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrG AGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFN------ETVLTVWSAPNYCYRCGNVAAILELDEH |... |..| ||. | |||. .||. . . ...|..|||||. | ||.|..... csyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyenn |
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| Phosphatase | PPP4C.AA | Subfamily.PPP_Nematode_2.PD | 23-281 | 43 | 3.5e-78 | 252.2 | In-house | 4-272 (281) | Show / Hide |
Range on Protein: 23-281 Range on HMM: 4-272/281 Sequence Identity: 43% (116 aa) SEVKALCAKAREILVEESNVQRVDS---PVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ |.. .. |.. ..| | . ||| |||| .|.|||. ||. .| . . . ..|||.||.|||| |||. |||||.|.||| . |.||||| . | eeiriisnyakkaflefsallrvdeeclpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvn ITQVYGFYDECLRKYGS--VTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT--TGWGVSPRGAGY |||.|||| ||. ||.. . |..| |.|.| .|..|.|||.|| .. |..| |.| || | ||||||||| | .||..| || . | ttltygffdeclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisf LFGSDVVAQFNAANDIDMICRAHQLVME----GYKWHFNETVLTVWSAPNYCYrCGNVAAILELDEHLQK . || .| | ||.|.. |||||. | |.|...| .....|| || .| ...| |.| sfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnyls-mkndssvlkleevktl |
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| Phosphatase | PPP4C.AA | Subfamily.PPP_Nematode_5.PD | 23-285 | 35 | 8.4e-72 | 231.3 | In-house | 4-269 (274) | Show / Hide |
Range on Protein: 23-285 Range on HMM: 4-269/274 Sequence Identity: 35% (92 aa) SEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQ ... . |....| . . .|..|.|..||||||. || .| | |...|||.||.|||| |.| |||..||..|| .. |.||||| ..| . kdilevlekikstlkplaalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkink VYGFYDECLRKYGsVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE--VPHDGPMCDLLWSDPED-TTGWGV-SPRGAGYLFG .|||..| .|.. .... ..| .|.| |... .|.|.|||.|| ...||..... . ...| . ||||.||| . . . |. .|| .| lygfkeelkkkrq-eslykkfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfG SDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFII .. |||.| |||... |||.. |.. ..||.||| |.. |..|.. ... |. |. kkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvv |
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| Phosphatase | PPP4C.AA | Subfamily.PPP_Nematode_3.PD | 74-287 | 40 | 4.9e-71 | 229.3 | In-house | 92-305 (308) | Show / Hide |
Range on Protein: 74-287 Range on HMM: 92-305/308 Sequence Identity: 40% (86 aa) ETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYgSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQT .|||.||.|||| .|.| .||.|||..|||...|.||||||| . . |||| |. ..| |.... .| | |.|... ||.|.|||.| .. |. ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkry-saalyeafqlafnvlplcavvnkkilcmhGGiseelld LDQIRTIDRKQEVPHDGPMCDLLWSDPEDT-TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAI |. ...| ..| | ..|| |.||. . .|. |.|||| .||.. | .|. |.|.. ||||.|..||.. . ..|..|||.|| . |.||.|. lkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav LELDEHLQKDFIIFE .|..|. . .. lsvdkklvisltvlr |
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| Phosphatase | PPP4C.AA | Subfamily.PPP_Nematode_7.PD | 22-280 | 31 | 1.9e-53 | 171.4 | In-house | 3-286 (296) | Show / Hide |
Range on Protein: 22-280
Range on HMM: 3-286/296
Sequence Identity: 31% (89 aa)
ESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELF-----------RVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITL
..|. |. .. | . .| .. .. |||. ||||||. || . ... .. ..|.||.|||| .|.||..|||. || .. |.||
knellslidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyil
IRGNHESRQITQVYGFYDE---CLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRK-QEVPHDGPMCDLLWSDPEDTTGW
|||.. | |.| | | | . ... |.| .. |.|.. ||.|||||.|| ...|..|. |.| .|| .| |||..|| |. . ..
lrGnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqll
GVSP----------RGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQ
|| . |. | .. .....| |||| .||.|. .. .||..|||.| .| |.|... .
aavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkveangk
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| Phosphatase | PPP4C.AA | Metallophos | 47-242 | 25 | 1.9e-43 | 155.42 | Pfam | 1-124 (124) | Show / Hide |
Range on Protein: 47-242 Range on HMM: 1-124/124 Sequence Identity: 25% (49 aa) SPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEI ....|||||||..||..||... . . ....|.||.|||| .| |...||...|..||... ..||||........|||| | ..| .. .. MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E--------NDW-MWWWW FDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVM | .. | ..|.||.|.||.. | |..| ..|.|. |. F-WMPLA-LDDWKILCMHGPP---------------------------------------------------------FCK-NGVDYVIRGHTHVP |
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| Phosphatase | PPP4C.AA | Subfamily.PPP_Nematode_1.PD | 30-287 | 24 | 1.1e-36 | 116.4 | In-house | 11-268 (273) | Show / Hide |
Range on Protein: 30-287 Range on HMM: 11-268/273 Sequence Identity: 24% (62 aa) AKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDE .| .|. | | .. ....|||.||| ... ||...... | .| .||.|...| | .|.|. |.|| |. || .. ..||..| . .. | edalkiaeetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrlige CLRKYGSVTVWRYCTEI----FDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTtgwgvSPRGAGYLFGS-DVVAQ .. || | | . |... |...|..|.|. |. ... ...|.. ... . | . || . ... .| . | | lrvrfpdsnkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfldidiP-----sPvtendidekskivke FNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFE .... |....| |||. ... ..|..||... |..| .| .|. .|. .| llkatdmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfklie |
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| Phosphatase | PPP4C.AA | Subfamily.PPP7C.PD | 192-287 | 32 | 7.2e-20 | 60.8 | In-house | 239-335 (338) | Show / Hide |
Range on Protein: 192-287 Range on HMM: 239-335/338 Sequence Identity: 32% (31 aa) MCDLLWSDPEDTTGW-GVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFE . |.|||||. ..| . ||.| ||.|| ... . ..... |.|. .|||.. |..|||..|| || | | . | ..|... . ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdltprivqyq |
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| Phosphatase | PPP4C.AA | Subfamily.PPP_Nematode_3.PD | 21-70 | 46 | 1.9e-13 | 40.2 | In-house | 2-51 (308) | Show / Hide |
Range on Protein: 21-70 Range on HMM: 2-51/308 Sequence Identity: 46% (23 aa) KESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGG ||.|. || .|||.. .| ....|||..||||||| ||. |. . | kekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG |
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