Gene PPP5C
PPP5C
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPP5C.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| TPR | PPP5C.AA | TPR | 28-61 | 44 | 5.3e-09 | 37.15 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 28-61 Range on HMM: 1-34/34 Sequence Identity: 44% (15 aa) AEELKTQANDYFKAKDYENAIKFYSQAIELNPSN || .. ..| |.| .||. ||..|..|.||.|.| AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR | PPP5C.AA | TPR_1 | 28-61 | 44 | 2.9e-09 | 36.31 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 28-61 Range on HMM: 1-34/34 Sequence Identity: 44% (15 aa) AEELKTQANDYFKAKDYENAIKFYSQAIELNPSN || .. .| |.| ..|. ||..| .|.||||.| AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR | PPP5C.AA | TPR_2 | 28-61 | 38 | 1.2e-08 | 34.72 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 28-61 Range on HMM: 1-34/34 Sequence Identity: 38% (13 aa) AEELKTQANDYFKAKDYENAIKFYSQAIELNPSN || . ... |.|..||. ||..| .|..|.| | AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR | PPP5C.AA | TPR_1 | 96-129 | 14 | 1e-06 | 27.46 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 96-129 Range on HMM: 1-34/34 Sequence Identity: 14% (5 aa) IKGYYRRAASNMALGKFRAALRDYETVVKVKPHD . .|.... ...|.. .|. .|. .... |.. AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| Phosphatase | PPP5C.AA | Subfamily.PPP5C.PD | 135-480 | 71 | 2.9e-194 | 634.5 | In-house | 1-346 (346) | Show / Hide |
Range on Protein: 135-480 Range on HMM: 1-346/346 Sequence Identity: 71% (246 aa) KYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKET |..||.|.||.||||.||||||.|.|||..||.|..|.||.|.|||||..|.|..|.|||....|.|||||.|.|..||...||.|.||..|||.| .|| klkeceklvkekafekaiagdeekksvvekldlealtveddyegpkleeekitkefvkellelfkkqkklhkkyalkilleakellkklpslveitipet EKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEV .|||||||.|||||||||||||||||||.|||.|||||||||||||||||||.|||||||.||.| |||||.||||..||||||||||||.....||.|| kkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhesdnmnklyGfegevkakytekvadlftev FEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGY |.|||||..|| |||..||||||||||||||.|||.||.|||..|....|||||||..|||| |||||..|||||||| ||.||||..||||||||.||| fnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqeanGrspskrGvgiqfGpdvtkkflkennleliirshevkeeGy EVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP ||.| |...|||||||||||||||...|.|.|.||.|.|..|.||. evehdGklitvfsapnycdqmgnkgafitlrgddlkpkfktfeave |
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| TPR | PPP5C.AA | TPR | 96-129 | 14 | 6e-06 | 26.96 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 96-129 Range on HMM: 1-34/34 Sequence Identity: 14% (5 aa) IKGYYRRAASNMALGKFRAALRDYETVVKVKPHD .. .|... . ...|.. |. .|. .... |.. AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| Phosphatase | PPP5C.AA | PP2Ac | 204-480 | 41 | 1.2e-167 | 564.21 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 204-480
Range on HMM: 1-321/321
Sequence Identity: 41% (134 aa)
LHRKCAYQILVQVKEVLSKLSTLVETT-LKETEKITVCGDTHGQFYDLLNIF---ELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHL
.|....||.. .|||........|| . . .|...|||||.||||.|||..| ..||.|.....| |.||.||||..|.|.|. ||..|..||..|.|
MHKHEIYQLCHEVKEIFRQEPNMVEVEET-PTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFL
LRGNHETDNMN---QIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFS-----EDGVTLDDIRKIER----NRQPPDSGPMCDLLW
||||||...|| |.|||..|.|.|| ..... |.|.|.|.||. .||.|.|.|||||.. .. .||||||.|.| ..||| |.||||||
LRGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLW
SDP---------QPQNGRSISK-RGVSCQFGPDVTKAFLEENNLDYIIRSHEVKA----EGYEVAHGG-----RCVTVFSAPNYCDQMGNKASYIHL---
||| |...|..... ||.|..|||||.. |.. ||||.|||.|... .|||. |.. ...|.|||||||||..|.|.....
SDPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDH
------QGSDLRPQFHQFTAVP
....|...|.||....
KVIQYKMDKNLKCHFVQFKPQM
|
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| Phosphatase | PPP5C.AA | Family.PPP.PD | 137-483 | 48 | 1e-140 | 458.8 | In-house | 3-343 (349) | Show / Hide |
Range on Protein: 137-483 Range on HMM: 3-343/349 Sequence Identity: 48% (166 aa) QECNKIVKQKAFERAIagDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKetek ....|..|.||...|. .|.|.| |..|..|... ........ .. |.|....|||....|..|.|..|.....| ..||.|.| ..|.| . .|||| kkikklakakaaakae--aeekksevkklsdeesievedsytgprlsfkltpdlvkelveafkekkqleakevlelleeakellkkepnlleveap---- ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKY--TAQMYELFSEV ||.||||.|||..|..||||...|.|.|.||.||||.|||||||.||..|||||..|.|||||||....|..|||..|||.|| ....||||.|||.|| itvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqev FEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGY |||..|..|.|..|||| |.. ..||.||||||. .||..|..||||||||..|.| . .||||...||||....||..||||.|||.|||. ||||. . FnwLPlaalidekilcvhGGl-speltsldqirkierpleppkegllcdllWsdpeeqkgwkpnkRGvgfvFgpdavekflkknnldliiRahevveeGy EVAHGGRCVTVFSAPNYCDQMGNKASYIHLqGSDLRPQFHQFTAVPHPN ....||.|||||||....|||..... . .|. .. || ...|. effanrklvTifsapnYcgeysnkaavlkv-dknlklsivqfkpskhkl |
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| Phosphatase | PPP5C.AA | Group.PPP.PD | 137-483 | 48 | 1e-140 | 458.8 | In-house | 3-343 (349) | Show / Hide |
Range on Protein: 137-483 Range on HMM: 3-343/349 Sequence Identity: 48% (166 aa) QECNKIVKQKAFERAIagDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKetek ....|..|.||...|. .|.|.| |..|..|... ........ .. |.|....|||....|..|.|..|.....| ..||.|.| ..|.| . .|||| kkikklakakaaakae--aeekksevkklsdeesievedsytgprlsfkltpdlvkelveafkekkqleakevlelleeakellkkepnlleveap---- ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKY--TAQMYELFSEV ||.||||.|||..|..||||...|.|.|.||.||||.|||||||.||..|||||..|.|||||||....|..|||..|||.|| ....||||.|||.|| itvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvygfyeevkskykkgeeiyelfqev FEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGY |||..|..|.|..|||| |.. ..||.||||||. .||..|..||||||||..|.| . .||||...||||....||..||||.|||.|||. ||||. . FnwLPlaalidekilcvhGGl-speltsldqirkierpleppkegllcdllWsdpeeqkgwkpnkRGvgfvFgpdavekflkknnldliiRahevveeGy EVAHGGRCVTVFSAPNYCDQMGNKASYIHLqGSDLRPQFHQFTAVPHPN ....||.|||||||....|||..... . .|. .. || ...|. effanrklvTifsapnYcgeysnkaavlkv-dknlklsivqfkpskhkl |
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| Phosphatase | PPP5C.AA | Subfamily.PPP_Nematode_6.PD | 211-464 | 43 | 1e-78 | 254.1 | In-house | 8-257 (272) | Show / Hide |
Range on Protein: 211-464 Range on HMM: 8-257/272 Sequence Identity: 43% (109 aa) QILVQVKEVLSKLSTLVETtlkeTEKITVCGDTHGQFYDLLNIFELNGLPSETNpYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMN ..| ..|.|..| ..||| |.|||| |||. ||| .|. .| | ..| |.| ||.||||..|.|||| |. .|..|..| |||||||. .|. kllelakkvfkkqkslvev----eapikvcGdihGqysdllrlfdkggfppdan-ylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceain QIYGFEGEVKAKYT-AQMYELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQP-QNGRSISKRGVSCQFGP .||| ||. .|. ...|. | |||..|||. . |..| ||||| |. .||..|...|..... |||||||. ..| . ..||||..|| |. rvyGfydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGl-skklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGe DVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHL |..||. ..| ..|.|.| .||| . . ||.||||.||.|. | |. ... davkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkv |
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| Phosphatase | PPP5C.AA | Subfamily.PPP4C.PD | 230-479 | 46 | 1.2e-78 | 254.0 | In-house | 22-270 (271) | Show / Hide |
Range on Protein: 230-479 Range on HMM: 22-270/271 Sequence Identity: 46% (115 aa) TLKE-TEKITVCGDTHGQFYDLLNIFELNGLPSETNpYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYT-AQM ... .||||| ||||||||..|...| ||| |.| ||||||| .||| .| | .|. |||. .|.|||||. .. |.||| |.|| |..... nvqrvdspvtvcgdihgqfydllelfkvggdvpetn-ylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqitqvygfydeclrkygsaev YELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSH .|||..|.|| |.||....|||| | . |||.|| |.|... |..||.||||||||. ..| ..| || || ||.. | |.|... |.|.|.. wryctevfdylslaaiidgkifcvhggl-spsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgsdvveqfneandielicrah EVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLqGSDLRPQFHQFTAV |||.. . .||.|||||| . ||.|. ..| ..|. .|. | |. qlvmegyklhfnekvltvwsapnycyrcgnvaailel-deeldkdfkifeaa |
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| Phosphatase | PPP5C.AA | Subfamily.PPP3C.PD | 205-486 | 40 | 2.7e-78 | 253.0 | In-house | 2-289 (292) | Show / Hide |
Range on Protein: 205-486 Range on HMM: 2-289/292 Sequence Identity: 40% (121 aa) HRKCAYQILVQVKEVLSKLSTLVETtlkeTEKITVCGDTHGQFYDLLNIFELNGLPSETNpYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNH ... | .|. .. ..|.| .||.| |||.|| ||||||||..||..| |..|. |.| ||.||||.||.|..| |. .|. ||....|||||| eeesalkiieeaakllkkeetllev----eapitviGdihGqfydllklfevgGkpastk-ylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnh ETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRS-------- |. . . . |. ||| ||. ..|| . | |. |||| .|.| | .|||| | . .||||.|..| ..|| |||.|||||||| . |.. ecrhlteyftfkeevkikyseevyealmesfdslplaallnqkflcvhGGl-speikslddikkldrfkeppasGplcdllwsdpledygeeetseeflp ISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHG------GRCVTVFSAPNYCDQMGNKASYIHLQGSDLrpQFHQFTAVPHPNVKP | || |. .. . ||..|.| |||.||.. .||.. . .|.||||||.| |||. .... .| . ..|.. .|| . | nsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyennvl--nirkfncsehpywlp |
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| Phosphatase | PPP5C.AA | Subfamily.PPP1C.PD | 211-464 | 41 | 1.2e-76 | 247.7 | In-house | 8-256 (271) | Show / Hide |
Range on Protein: 211-464 Range on HMM: 8-256/271 Sequence Identity: 41% (106 aa) QILVQVKEVLSKLSTLVETtlkeTEKITVCGDTHGQFYDLLNIFELNGLPSETNpYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMN ..... .|.. . .|.| . ..|| |||..||| .|| .| |.|.| |.| ||.|||| |.| |. |. .|. ||..|.|||||||. ..| klclkareiflsqpillel----eaplkivGdihGqyadllrlfekggfppesn-ylflGdyvdrGkqsletivlllaykikypenffllrGnhecasin QIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPD .|||| |.| .|. .... | ..|..||.| .. |....|||| | | .|..||.|.| . ||.| .||||||||. ..| . ..|||| || || riygfydeckrryniklwktfvdcfnclpvaaivdekifcvhGGl-spdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfgad VTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHL . ||....|| |.|.|.| .||| . . ||.|||||||... | .. . . vvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsv |
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| Phosphatase | PPP5C.AA | Subfamily.PPP2C.PD | 216-478 | 43 | 2.5e-74 | 239.9 | In-house | 13-269 (271) | Show / Hide |
Range on Protein: 216-478 Range on HMM: 13-269/271 Sequence Identity: 43% (113 aa) VKEVLSKLSTLVETTLketeKITVCGDTHGQFYDLLNIFELNGLPSETNpYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGF ||.||| | . | . .||||| ||||.|||..| . | .|| |.| ||.|||| .|||.. | .|. |.. .||||||... |.||| akeilskesnvkevkc----pvtvcgdvhgqfhdllelfriggkspdtn-ylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqitqvygf EGEVKAKYT-AQMYELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAF |. ||. |.....|...|..|||. ...... .|||| | |||.||...| .. | |||||||||||. ..| .|| || .|| |....| . ydeclrkygnanvwkyftdlfdylpltalvdnqifclhggl-spsidtldkiraldrlqevphegpmcdllwsdpddrggwgisprgagytfgkdiseef LEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQgSDLRPQFHQFTA .|.| . |.|.. |||. .| ||.||||||| . ||.|. . |. .|. .| || nktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaaileld-delkysflqfdp |
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| Phosphatase | PPP5C.AA | Subfamily.PPP6C.PD | 228-480 | 44 | 6.4e-74 | 238.4 | In-house | 20-271 (271) | Show / Hide |
Range on Protein: 228-480 Range on HMM: 20-271/271 Sequence Identity: 44% (112 aa) ETTLK-ETEKITVCGDTHGQFYDLLNIFELNGLPSETNpYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYT-A |.... . .||||| |||||||...| | .|. |.| ||||||| .|.| . .|. .|. |||. |||||||. .. |.||||.. || |. esnvqpvsspvtvcgdihgqfydleelfrtggqvpdts-yvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqitqvygfydeclnkygna QMYELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIR . ...||. |..| |...|| .|||| | | |||.|| |||... | |..|||.||||. . ..|.|| ||||| |.. |||. |.|.|.. nawkyctkvfdlltiaaiideqvlcvhggl-spdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgskvtkefvhinnlklicr SHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDlRPQFHQFTAVP ||.. . |||.|||||| . || || ..|. .. ... |.||| ahqlveeglkymfdeklvtvwsapnycyrcgniasilaledae-ereaklfkavp |
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| Phosphatase | PPP5C.AA | Subfamily.PPP_Nematode_5.PD | 209-465 | 38 | 2.3e-69 | 223.3 | In-house | 6-260 (274) | Show / Hide |
Range on Protein: 209-465 Range on HMM: 6-260/274 Sequence Identity: 38% (99 aa) AYQILVQVKEVLSKLSTLVETtlkeTEKITVCGDTHGQFYDLLNIFELNGLPSETNpYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDN ...| ..|..| |..|.| .. ||..||.|||. |||.||. | ..... |.| ||.||||. |.||.| || .|..|| . |||||||| .. ilevlekikstlkplaallev----eapitivGdihGqlddllrifnavGaapkvq-ylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkk MNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDS--GPMCDLLWSDPQPQ-NGRSISK-RGVSC |..|||. |.| |. ..|. | .||. ||| .. ..| ||||. |.. .||... .....| . | . ||||.||. . .. . | |..| | inklygfkeelkkkrqeslykkfndvfselplcarvskrilcmhGGi-spklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisv QFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQ | . .|.. ..| |.|.|||. |||. |.||||||||. . | .. .... vfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvs |
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| Phosphatase | PPP5C.AA | Subfamily.PPP_Nematode_4.PD | 212-476 | 38 | 2.4e-69 | 223.5 | In-house | 9-267 (271) | Show / Hide |
Range on Protein: 212-476 Range on HMM: 9-267/271 Sequence Identity: 38% (102 aa) ILVQVKEVLSKLSTLVETtlkeTEKITVCGDTHGQFYDLLNIFELNGLPSETNpYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQ .. ......|. ..||| | | || |.|| || ..|.| | . |. ..| ||.|||| ..||.. || .|. |.|. |||||||. ..|. vireaeaifsdekalvei----eapikvvgdlhaqfqdlirlfdllgrvpeek-lvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnk IYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDV .||| |.. || ... .| ..|. ||... | ||| ||||| | . ..||..| | . ...| | . ||||.||... .. | ||.| || .| kygfyeecvtkygeelwadfqrcfnrlpisaliakkvlcmhggl-spelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgv TKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQgSDLRPQFHQF . . ..| |||.|.| .|||| | . .||||.||||.|.| |. . |. ..|. .. .. vedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkld-enleislval |
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| Phosphatase | PPP5C.AA | PPP5 | 135-229 | 63 | 1.8e-64 | 215.61 | Pfam | 1-97 (97) | Show / Hide |
Range on Protein: 135-229 Range on HMM: 1-97/97 Sequence Identity: 63% (62 aa) KYQECNKIVKQKAFERAIAG-DEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYK-DQKKLHRKCAYQILVQVKEVLSKLSTLVET |..||.|||.|.||||||. ||..|||.|..|.|.|||||.|.||.|||.|||| |||..|.|.| .|||||.|||||||.||||.|.|...||.. KLKECEKIVRQIAFERAIHVPDEQPRSVYDMIDMENMTIEDDYDGPRLEDNKVTIEFMKDMMEWFKVQQKKLHKKCAYQILCQVKEILKKCPSLVDI |
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| Phosphatase | PPP5C.AA | Subfamily.PPP_Nematode_3.PD | 264-465 | 45 | 2.2e-64 | 207.4 | In-house | 93-294 (308) | Show / Hide |
Range on Protein: 264-465 Range on HMM: 93-294/308 Sequence Identity: 45% (91 aa) NPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTL . |.| ||.|||| ||.||.. || .||||||. .|||||||. ..|. ||| ||| .| |..|| | .|. |||. .||.| ||||. ||. . |. kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysaalyeafqlafnvlplcavvnkkilcmhGGi-seelldl DDIRKIERNRQPPDSGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYI . |..| . || | ..|| |.||... .| |.|| . ||.. |.||.. .|| ..|.|.| .||| . . ||.||||.|| |. | |. .. kqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavl HLQ .. svd |
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| Phosphatase | PPP5C.AA | Subfamily.PPP_Nematode_2.PD | 217-466 | 43 | 1.4e-62 | 201.0 | In-house | 14-268 (281) | Show / Hide |
Range on Protein: 217-466 Range on HMM: 14-268/281 Sequence Identity: 43% (109 aa) KEVLSKLSTLVETTlKETEKITVCGDTHGQFYDLLNIFELNGLPSEtNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFE |. . . |.|.. .|. .|| .| |||. ||| || .|. |. . |.| ||.||||. ||||.| |. .| |||||||||||| | ||| | kkaflefsallrvd-eeclpvtvvadlhgqsidllriflineapgi-skylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvnttltygff GEVKAKYTA---QMYELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQP--QNGRSISKRGVSCQFGPDVT . ||. ... . . |. |||| | .||| .|||. | |.|| |||| || ||||||||. ..| |.|.||.| |. | . | declekyndkgekvwlmiidafnhlplaalildkvlcahggi-sphlekledidkierplvvpsyglacdllwsdpektervgwslsargisfsfddivv KAFLEENNLDYIIRSHEVKAE----GYEVAHGGRCVTVFSAPNYCdQMGNKASYIHLQG ..|.|| ..|.|.. | |. . .|| |..||| |||.|..| ..|. ekfcadndldlvvrahqlskemirqghklrangrlvslfsalnyl-smkndssvlklee |
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| Phosphatase | PPP5C.AA | Subfamily.PPP7C.PD | 168-373 | 43 | 1.3e-61 | 198.1 | In-house | 2-207 (338) | Show / Hide |
Range on Protein: 168-373 Range on HMM: 2-207/338 Sequence Identity: 43% (91 aa) ESMTIEDEYSGPKLEDgKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYI ||. ..|.|.||.|. .... ...|.. .| .|.|| | .|| . |.|| .| .. . . ....||||| ||.. ||| |. |||||. |||. esievpdsytgprlsf-plllddveklleafklkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyv FNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKY---TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLfsEDGVTLD |||||||||. |||..| || . |.|| ...| ||||| .| ||| ||. || .... .|. .|| ||||| |.|.||.|||. | |. fnGdfvdrGkesveillilfalllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGi--sdktdle DIRKIERNR . ||||.. lldkiersk |
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| Phosphatase | PPP5C.AA | Subfamily.PPP_Nematode_7.PD | 212-466 | 32 | 2.4e-47 | 151.3 | In-house | 9-283 (296) | Show / Hide |
Range on Protein: 212-466 Range on HMM: 9-283/296 Sequence Identity: 32% (89 aa) ILVQVKEVLSKLSTLVETtlkeTEKITVCGDTHGQFYDLLNIF----------ELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR .. .|||...| ||.| .|. || |||. || | . .|. .. ..| ||.||||| |.| |.| .|.||| .. ||||| lidavkelfkkektlaei----spPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyillr GNHETDNMNQIYGFEGEVKA----KYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLfSEDGVTLDDIRKIERNRQPPDSG-PMCDLLWSDPQPQ---- ||| .| |.|. |.. . . ..|| | ||| ..||| . |.| .|||. |..|.||..||| .. . |||..|| Gnhetkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggi-spklesledinsierPlaevtedslakdllfadpldvqlla ------NGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQG . .. .||.| |. . . . .||. |.|.|. .||.. . .|.||||.| ....|. . ..... avsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkvea |
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| Phosphatase | PPP5C.AA | Metallophos | 235-431 | 26 | 7.9e-38 | 136.8 | Pfam | 1-124 (124) | Show / Hide |
Range on Protein: 235-431 Range on HMM: 1-124/124 Sequence Identity: 26% (52 aa) EKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEV .|..|||.|||..|| |... . . . . .||.||.|||| | |.|. || .|..||......||||. ...|. ||| | .. .. .. MRILHCGDIHGQYDDL-NRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E-------NDW-MWWWW FEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKA | |.||| ...|.|.|||.. |.. |..||.|| |. . F-WMPLA-LDDWKILCMHGPP----------------------------------------------------------FCK-NGVDYVIRGHTHVP |
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| Phosphatase | PPP5C.AA | Subfamily.PPP7C.PD | 381-478 | 46 | 3.1e-32 | 101.5 | In-house | 239-336 (338) | Show / Hide |
Range on Protein: 381-478 Range on HMM: 239-336/338 Sequence Identity: 46% (46 aa) MCDLLWSDPQPQNGRS-ISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLqGSDLRPQFHQFTA . |.|||||. |.| . || . ||||||| .|. ||...||||| | ||||..|. ...|.||| || .. |. .|..| |.||.|.. |. | ildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvkl-gkdltprivqyqa |
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| Phosphatase | PPP5C.AA | Subfamily.PPP_Nematode_1.PD | 228-460 | 26 | 6.3e-24 | 74.6 | In-house | 19-252 (273) | Show / Hide |
Range on Protein: 228-460 Range on HMM: 19-252/273 Sequence Identity: 26% (63 aa) ETTLKE--TEKITVCGDTHGQFYDLLNIFELNGLPSEtNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKA---- ||.| | . ..||.|| ... |||.|..| | | | . ..| |...| | .|.| .| |. | || .. .|||..||.. . ||.. etslleyieadvtviGdirsryadlldilkltGwPfe-qkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrligelrvrfpd --KYTAqMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEdGVTLDDIRKIERNR---QPPDSGPMCDLLWSDPQPQNGRSISKRGvscqfgpDVTKAFLE |. | . . .. . ||.| .| |.| ...|. | ... ..|. .. .. | |.|. | .. . | | .. snkwra-lnaiikrllkrlPvaavlnkkllavysgvssn-ikekknvvavkrgiifenhstrvevqfldidiPsPvtendideks-------kivkellk ENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKAS . .|||..| ||| . | .|..||... . |. atdmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGv |
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| Phosphatase | PPP5C.AA | Subfamily.PPP_Nematode_3.PD | 235-261 | 58 | 3.1e-08 | 23.1 | In-house | 28-54 (308) | Show / Hide |
Range on Protein: 235-261 Range on HMM: 28-54/308 Sequence Identity: 58% (14 aa) EKITVCGDTHGQFYDLLNIFELNGLPS .|..|| |||| ||| ...||| | apvtivGdihGqfedllalldlnGwpl |
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