Gene PPP6C
PPP6C
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPP6C.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPP6C.AA | PP2Ac | 56-326 | 39 | 9.60000000001e-142 | 478.11 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 56-326
Range on HMM: 1-321/321
Sequence Identity: 39% (127 aa)
FLRFLKERLCDYVCDLLLEESNVQPVS----TPVTVCGDIHGQFYDLCELF---RTGG-QVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLL
. . .||..|.... |.|. .|. ||||||||||||.|| .|| . .| ..|.||| |.||.||||..|.|. ..|...| ..|....||
MHKHEIYQLCHEVKEIFRQEPNMVEVEETPTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFLL
RGNHESRQIT---QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSP------DIKTLDQIRTIER----NQEIPHKGAFCDLVWS
|||||.|... |.|||||||. ||.... | ... .|... ..|||. .|||.|||||| .|.|||.|| |.| ||.|..| ||| ||
RGNHECRHMNMWVQYYGFYDECKRKYYHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQHPPQEPPDWGLMCDLLWS
DP---------EDVDTWAISP-RGAGWLFGAKVTNEFVHINNLKLICRAHQLVH----EGYKFMFDE-----KLVTVWSAPNYCYRCGNIASIMVF----
|| .|. | ... ||.. ||..|..|| . |||.||.||||.| .||.|..|. ||.|..||||||..|.| |..| .
DPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHK
------KDVNTREPKLFRAVP
.. ...|....
VIQYKMDKNLKCHFVQFKPQM
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| Phosphatase | PPP6C.AA | Subfamily.PPP6C.PD | 61-326 | 84 | 1.1e-173 | 565.6 | In-house | 6-271 (271) | Show / Hide |
Range on Protein: 61-326 Range on HMM: 6-271/271 Sequence Identity: 84% (226 aa) KERLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVY ...|||.|.|||||||||||||.|||||||||||||||.||||||||||||.|.|.|||||||||||||||.||.||||.|||||||||||||||||||| lkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqitqvy GFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNE ||||||..||||||||.|||||||.||.||.||||.||||||||||.|||||||.|||.||||||||||||||||||||.|||.||||||.|||.|||.| gfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqeiphkgafcdlvwsdpedvetwavsprgagylfgskvtke FVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVP |||||||||||||||||.||.|.|||||||||||||||||||||||||. ..| ..||.|||.||| fvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasilaledaeereaklfkavp |
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| Phosphatase | PPP6C.AA | Subfamily.PPP4C.PD | 63-325 | 66 | 3.2e-142 | 462.5 | In-house | 8-270 (271) | Show / Hide |
Range on Protein: 63-325 Range on HMM: 8-270/271 Sequence Identity: 66% (175 aa) RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGF .|| . ..|.|||||| | .||||||||||||||| |||. ||.||.|||.|.|||||||.||.||| |||||...||||||.||||||||||||||| alcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqitqvygf YDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFV |||| |||.|. |||||.|||.|..||.||..|.||||||||.|.|||.||.|.|.||.||.|..|||.||||||...||.||||||.|||..|...|. ydeclrkygsaevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedaegwavsprgagylfgsdvveqfn HINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAV . |...||||||||| ||||..|.||..||||||||||||||.|.|. ... .. |.| |. eandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaa |
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| Phosphatase | PPP6C.AA | Subfamily.PPP2C.PD | 63-315 | 62 | 2.4e-128 | 417.0 | In-house | 8-260 (271) | Show / Hide |
Range on Protein: 63-315 Range on HMM: 8-260/271 Sequence Identity: 62% (158 aa) RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGF .||. ..| .||||..|..|||||||.||||.|| |||| ||..|||||.||||.|||||||.|| |.|.||| ....|||.|||||||||||||||| klcekakeilskesnvkevkcpvtvcgdvhgqfhdllelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqitqvygf YDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFV |||| |||||| |.| | .||.| ..||.|.||.|.|||||| |.|||.||...| ||.||.|..|||.||||.| |.|||||||. || ....|| ydeclrkygnanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldrlqevphegpmcdllwsdpddrggwgisprgagytfgkdiseefn HINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVN . |.|.|..|||||| |||.. |...||..||||||||||| |.|. . | ktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddel |
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| Phosphatase | PPP6C.AA | Family.PPP.PD | 63-328 | 47 | 1.2e-124 | 405.9 | In-house | 75-342 (349) | Show / Hide |
Range on Protein: 63-328 Range on HMM: 75-342/349 Sequence Identity: 47% (127 aa) RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDT-NYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG .|.. ...|| .|.|.. |..|.||||||||||.||..||...|. |.. .|.|.||.||||..|.|....|.|||...|.|..|||||||||....||| elleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvyg FYDECQTKYGN-ANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNE ||.|...|| . .. ......||..|..||||||.||||||||||....|||||.|||..|.|..|..|||.|||||... |. ..||.|..||...... fyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkgwkpnkRGvgfvFgpdavek FVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDS |.. |||.||.|||..|.|||.|....||||..||||||....|.|... ... . . ..|..... flkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhk |
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| Phosphatase | PPP6C.AA | Group.PPP.PD | 63-328 | 47 | 1.2e-124 | 405.9 | In-house | 75-342 (349) | Show / Hide |
Range on Protein: 63-328 Range on HMM: 75-342/349 Sequence Identity: 47% (127 aa) RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDT-NYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG .|.. ...|| .|.|.. |..|.||||||||||.||..||...|. |.. .|.|.||.||||..|.|....|.|||...|.|..|||||||||....||| elleeakellkkepnlleveapitvcGDihGqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvyg FYDECQTKYGN-ANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNE ||.|...|| . .. ......||..|..||||||.||||||||||....|||||.|||..|.|..|..|||.|||||... |. ..||.|..||...... fyeevkskykkgeeiyelfqevFnwLPlaalidekilcvhGGlspeltsldqirkierpleppkegllcdllWsdpeeqkgwkpnkRGvgfvFgpdavek FVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDS |.. |||.||.|||..|.|||.|....||||..||||||....|.|... ... . . ..|..... flkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhk |
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| Phosphatase | PPP6C.AA | Subfamily.PPP1C.PD | 63-312 | 47 | 2.4e-93 | 302.4 | In-house | 8-257 (271) | Show / Hide |
Range on Protein: 63-312 Range on HMM: 8-257/271 Sequence Identity: 47% (119 aa) RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGF .|| ...|.. . ...|. ..||||||..|| || .|| |..||.|.||.|||| |||| . |||.| |.|... |||||||..|...|||| klclkareiflsqpilleleaplkivGdihGqyadllrlfekggfppesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecasinriygf YDECQTKYgNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAISPRGAGWLFGAKVTNEF |||. .| | . |. . .|..| |||..||.|.|||||||||.|.|.||| |.| ..|.|| .|||.||||. .| .|.. || . |||.| ..|.. ydeckrry-niklwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarptdvpdkGllcdllwsdpdkevkgwgendrgvsftfgadvvekf VHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFK ..|.||.||||.| .||.|. . .|||..|||||| . |....|. . lkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvd |
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| Phosphatase | PPP6C.AA | Subfamily.PPP_Nematode_6.PD | 63-312 | 43 | 5.4e-86 | 278.0 | In-house | 8-258 (272) | Show / Hide |
Range on Protein: 63-312 Range on HMM: 8-258/272 Sequence Identity: 43% (108 aa) RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGF .|.. . ... ... . | .|..||||||||. || || || ||.||.|.||.|||| .|||. . ||| |.|.|...||||||| .| .||||| kllelakkvfkkqkslveveapikvcGdihGqysdllrlfdkggfppdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceainrvyGf YDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPED-VDTWAISPRGAGWLFGAKVTNEF ||.| .| ... . .||..| ..||. ..|||.|||||. .|.|||.|...| .. ...||.|||||. |. || . ||.. ||... ..... . ydevqrrykstrlyaafqevfnalpltalvsgrilcmhGGlskklksldqlrelkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGedavkkl VHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFK . |..||||.| .||.|. . ||||..|||.|| . | |..| . lekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvd |
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| Phosphatase | PPP6C.AA | Subfamily.PPP3C.PD | 63-313 | 41 | 2.5e-80 | 259.7 | In-house | 8-271 (292) | Show / Hide |
Range on Protein: 63-313 Range on HMM: 8-271/292 Sequence Identity: 41% (108 aa) RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGF .. . ...|| .|... |..|.||.|||||||||| .|| ||. .|.|.|.||.|||||.|.|. ||.||| ..|.|. |||||||.|..|. . | kiieeaakllkkeetlleveapitviGdihGqfydllklfevgGkpastkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhlteyftf YDECQTKYGNaNAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPE-DV------DTW-AISPRGAGWLFG .|...||.. . . ... ||.| .|||.... |||||||||.||.||.|....| .|.|..|..|||.|||| |... |.|| .... | . || keevkikyse-evyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfkeppasGplcdllwsdpledygeeetseeflpnsvrGcsyfys AKVTNEFVHINNLKLICRAHQLVHEGYKFMFD------EKLVTVWSAPNYCYRCGNIASIMVFKD .. |.| | |||. ..||. . |.|..|||||. | |... ... ykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkyen |
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| Phosphatase | PPP6C.AA | Subfamily.PPP_Nematode_4.PD | 70-312 | 40 | 1.3e-78 | 253.9 | In-house | 15-257 (271) | Show / Hide |
Range on Protein: 70-312 Range on HMM: 15-257/271 Sequence Identity: 40% (99 aa) DLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTK .. .|... . .|. | ||.|.|| || .|| |.||.. ..|.||.|||| ..|.. |..|| ...||| ||||||| .. ..||||.||.||| aifsdekalveieapikvvgdlhaqfqdlirlfdllgrvpeeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnkkygfyeecvtk YGNaNAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLK |. . | ..|. | ..||| ...||.||||||.. .||..| | . | ...| ||.|.||. .| | | ||....|| .| .. . ...| yge-elwadfqrcfnrlpisaliakkvlcmhgglspelisldelrnipkpienldrgllidllwadpdnkveewkasirgisytfgkgvvedvckslevd LICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFK | ||||.|..||. . ||.||.|.|||| | |... . liirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkld |
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| Phosphatase | PPP6C.AA | Subfamily.PPP5C.PD | 82-325 | 43 | 2.5e-78 | 253.2 | In-house | 100-345 (346) | Show / Hide |
Range on Protein: 82-325 Range on HMM: 100-345/346 Sequence Identity: 43% (108 aa) STPVTVCGDIHGQFYDLCELFRTGGQVPD-TNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNaNAWRYCT .. .|||||||||||||...|. |.. . |.| ||||||| .|.|. ||..| .|... | |||||| .. ..||| .|...||. . |. tkkitvCgdihgqfyDllnifelnGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhesdnmnklyGfegevkakyte-kvadlft KVFDMLTVAALIDEQILCVHGGL-SPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHE ||. | .| .|.|..| ||||| | | |||..|.|.||.. |..|....|.||||.. . | || | || ||..|.. |||.|| |.|.. .|| evfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeeglllellwsdpqeanGrspskrGvgiqfGpdvtkkflkennleliirshevkee GYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTR-EPKLFRAV |... | ||.||.|||||| . || .... .. . . . | | || GyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkfktfeav |
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| Phosphatase | PPP6C.AA | Subfamily.PPP_Nematode_5.PD | 81-313 | 38 | 3.8e-71 | 229.1 | In-house | 26-261 (274) | Show / Hide |
Range on Protein: 81-313 Range on HMM: 26-261/274 Sequence Identity: 38% (91 aa) VSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGnANAWRYCT | .|.|..||||||. || .| |. |...|.|.||.|||| ||| .|..|| ..| .. ||||||| ..| ..|||..| . |.. . .. veapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkinklygfkeelkkkrq-eslykkfn KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEI--PHKGAFCDLVWSDPE-DVDTWAIS-PRGAGWLFGAKVTNEFVHINNLKLICRAHQL .|| |.. | ....|||.|||.||..|.||....... . ..| ||.|.||| | .|.. |. .|| |. ..... ...|| |||... dvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldidlivrahev VHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKD .|||.|.||..||||.||| |. . |.....| .. seeGyaflfdkrlvtvfsapyysgedtnlgavvvvsk |
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| Phosphatase | PPP6C.AA | Subfamily.PPP_Nematode_3.PD | 110-312 | 43 | 2.9e-70 | 226.8 | In-house | 92-294 (308) | Show / Hide |
Range on Protein: 110-312 Range on HMM: 92-294/308 Sequence Identity: 43% (87 aa) DTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNaNAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKT .|.|.||.|||| .|.| . |.||| ..||...||||||||| . . |||| |.. .| . . . ..| .| ..|.....|||.|||.| .. |. ykkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysa-alyeafqlafnvlplcavvnkkilcmhGGiseelld LDQIRTIERNQEIPHKGAFCDLVWSDPE-DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASI |. ...| .|| | .||.|.||. .|.... |.|||| .|||| .||.. .|.|. ||||.|..||.|. | ||||..|||.|| . |||... lkqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaav MVFK . lsvd |
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| Phosphatase | PPP6C.AA | Subfamily.PPP_Nematode_2.PD | 82-316 | 41 | 1.2e-69 | 224.2 | In-house | 30-271 (281) | Show / Hide |
Range on Protein: 82-316 Range on HMM: 30-271/281 Sequence Identity: 41% (100 aa) STPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNA--NAWRYC . |||| .|.|||. || .| . . . ..|.|.||.|||| |.|. |||.| ..|| . ||||||| . | |||.|||. ||.. .|.. clpvtvvadlhgqsidllriflineapgiskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvnttltygffdeclekyndkgekvwlmi TKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD--TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV . |..| .|||| ...||.|||.|| .. |..| ||| .| | |||.||||| .|..| || . |. | ..| . |.|.|. |||||..| idafnhlplaalildkvlcahggisphlekledidkierplvvpsyglacdllwsdpektervgwslsargisfsfddivvekfcadndldlvvrahqls HE----GYKFMFDEKLVTVWSAPNYCYrCGNIASIMVFKDVNT |.|. .. .||...|| || .| .|.. .. |.| kemirqghklrangrlvslfsalnyls-mkndssvlkleevkt |
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| Phosphatase | PPP6C.AA | Subfamily.PPP_Nematode_7.PD | 64-311 | 34 | 2.2e-55 | 177.7 | In-house | 9-281 (296) | Show / Hide |
Range on Protein: 64-311
Range on HMM: 9-281/296
Sequence Identity: 34% (95 aa)
LCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELF------RTGGQV-----PDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHE
|.| | .|. .| .. .|.|||. ||||||. || . . | . ..|.||.||||..|.| . ..||| .| .. |||||||
lidavkelfkkektlaeispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyillrGnhe
SRQITQVYGFYDECQTKYGNA---NAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERN-QEIPHKGAFCDLVWSDPEDVDTWAISP--
.. | |.| | ... ... . . .|| . .|||. |.|||||||.|| ...|..|. ||| .|. .. ||...|| ||.. |..
tkainfayefreelenrlskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierPlaevtedslakdllfadpldvqllaavsek
--------RGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVF
|| . |. . ... . .||||| |||| . ||.||.|.||.|..|||.| .| ... .
pkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkv
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| Phosphatase | PPP6C.AA | Subfamily.PPP_Nematode_1.PD | 68-320 | 23 | 3.9e-38 | 121.2 | In-house | 13-265 (273) | Show / Hide |
Range on Protein: 68-320 Range on HMM: 13-265/273 Sequence Identity: 23% (59 aa) VCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQ ... | | .. . ..|||.||| ... || ..... | .. ..|.|...| | .|||. || | .| .. .|||..| . .. | . . alkiaeetslleyieadvtviGdirsryadlldilkltGwPfeqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrligelr TKYGNANAWRYCTK----VFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSdpeDVDtwAISPRGAGWLFGA-KVTNEFV . ..| || . | |||... ..|.|..|.|. || ... ...|.. .. ... . |.| || . ... |. | . . vrfpdsnkwralnaiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiifenhstrvevqfl---did--iPsPvtendidekskivkell HINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPK .... |....|.|||.| ....|.|..||... | ..... . ..| katdmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsidkdlkvtfk |
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| Phosphatase | PPP6C.AA | Metallophos | 83-278 | 25 | 8.9e-38 | 136.62 | Pfam | 1-124 (124) | Show / Hide |
Range on Protein: 83-278 Range on HMM: 1-124/124 Sequence Identity: 25% (49 aa) TPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKV ....|||||||..|| .||. . . .....||.||.||||..|.|.. .|...| . |... ..||||........|||| | |.| .. .. MRILHCGDIHGQYDDLNRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E--------NDW-MWWWW FDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVH | . | |.| |||.||.. |. |......|.|. | F-WMPLA-LDDWKILCMHGPP---------------------------------------------------------FCK-NGVDYVIRGHTHVP |
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| Phosphatase | PPP6C.AA | Subfamily.PPP7C.PD | 81-220 | 42 | 8.4e-35 | 109.9 | In-house | 66-207 (338) | Show / Hide |
Range on Protein: 81-220 Range on HMM: 66-207/338 Sequence Identity: 42% (60 aa) VSTPVTVCGDIHGQFYDLCEL-FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYG--NANAWR .| ||||||.||.. ||. . .. | .. .|.| ||||||| |.| |.|| .| . | ||||| . ||| | ..||... | iskevtvcgdlhgklddlllilyknGlpsaenpyvfnGdfvdrGkesveillilfalllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilr YCTKVFDMLTVAALIDEQILCVHGGLSpDIKTLDQIRTIERNQ .|| | .|.||||.|| ||||.| |. |. . |||.. lledvfawlplatlidekilivhGGis-dktdlelldkiersk |
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| Phosphatase | PPP6C.AA | Subfamily.PPP7C.PD | 229-311 | 33 | 1.9e-18 | 56.2 | In-house | 240-323 (338) | Show / Hide |
Range on Protein: 229-311 Range on HMM: 240-323/338 Sequence Identity: 33% (28 aa) CDLVWSDPEDVD-TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVF |..||||. . .. . ||.| ||. ||..... ||.|. |.|. .|||.|. ..|..|..|| || | . . . ldilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvkl |
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| Phosphatase | PPP6C.AA | Subfamily.PPP_Nematode_3.PD | 64-105 | 43 | 4.7e-08 | 22.4 | In-house | 9-50 (308) | Show / Hide |
Range on Protein: 64-105 Range on HMM: 9-50/308 Sequence Identity: 43% (17 aa) LCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTG || .|. .| . .|||..||||||| || |. lcyrarelfwkeplkleleapvtivGdihGqfedllalldln |
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