PPEF1
Species: Human
Alias: PPP7C, PP7, PPEF, PPEF1
External Links: COSMIC , Entrez Gene
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: PPP
Family: PPP
Subfamily: PPP7C
Protein domain

Protein domains of PPEF1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
IQ PPEF1.AA IQ 17-37 57 6e-06 23.12 Pfam 1-21 (21) Show / Hide
Range on Protein: 17-37
Range on HMM: 1-21/21
Sequence Identity: 57% (12 aa)

LRAALIIQNWYRGYKARLKAR
 |||..|| |.|||.|| . |
HRAAIKIQAWWRGYLARKHYR

Phosphatase PPEF1.AA Family.PPP.PD 75-456 36 9.80000000001e-129 419.4 In-house 10-341 (349) Show / Hide
Range on Protein: 75-456
Range on HMM: 10-341/349
Sequence Identity: 36% (139 aa)

KEELELRNQSLEsEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIqTSPskeVTICGDLH
|.. . .... | ..   .. . ..||.|.|||.||||.|.||.. .. |.|||||.. |.|..|||.| |.|..||..||.... ..|   .|.|||.|
kakaaakaeaee-kksevkklsdeesievedsytgprlsfkltpdlvkelveafkekkqleakevlelleeakellkkepnllev-eap---itvcGDih

GKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLhGKRILQILEEFYAWLPIG
|..|||. .|..||||...|.|.|.||.|||||.|.|....|..  |.||. ..|.|||||. ..| .|||..|. .|||  |..|.....|. |||. .
GqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvygfyeevkskykk-geeiyelfqevFnwLPla

TIVDNEILVIHGGISE-TTDLNLLHRVERNKmksvlipptetnrdhdtdskhnK-VgvtfnahgriktngsptehltehEWEQIIDILWSDPRGKNGCFP
..|..||..|||.|. .|.|. ....||..                      .                         ......|.|||||. ..|. ||
alidekilcvhGGlspeltsldqirkierpl----------------------epp-----------------------kegllcdllWsdpeeqkgwkp

NTcRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKA
. ||.|..||||...|.|.|..|...||.||...||||.....|.||||||.||..|.||..|..|.    . ...|.. .|  
nk-RGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskh

Phosphatase PPEF1.AA Subfamily.PPP7C.PD 99-455 61 1.7e-188 615.2 In-house 2-338 (338) Show / Hide
Range on Protein: 99-455
Range on HMM: 2-338/338
Sequence Identity: 61% (219 aa)

DSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVF
.||.|||||.||||.|||...|.. ||||||....|||.|||..|.||||||||.||.....|. |||||.|||||||||||.||.|||||||..|||||
esievpdsytgprlsfplllddveklleafklkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyvf

NGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLH
|||||||||.|.|||.||....||||....||||||||...||||||.||. .||| |||.||..||...||||..|..|..||..|||||..|||.||.
nGdfvdrGkesveillilfalllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdktdlelld

RVERNKMKSVLIPPtETNRDHDTDSKHNKvgvtfnahgriktngspteHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKM
..||.|..||| || .........|...|                   .||..||.||.|||||||. ..||.|||.||||.|||||||.|.|.||.|..
kiersklvsvlkpp-rlkeeaesesgeek-------------------kltleewrqildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlel

LIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTK
|||||||||||||..|. ||.||||||||||||||||||.||.. .|||..|||..|
lirsheckpeGyefthnkkvltifsasnyyeeGsnrGayvklgkdltprivqyqask

Phosphatase PPEF1.AA PP2Ac 134-455 31 1.1e-139 471.27 SMART 1-321 (321) Show / Hide
Range on Protein: 134-455
Range on HMM: 1-321/321
Sequence Identity: 31% (112 aa)

LHAHYVLEVLFETKKVLKQMPNFTHIQ-TSPSKEVTICGDLHGKLDDLFLIF---YKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHL
.|.|.......| |....|.||. ... | |.  ||.|||.||..|||. .|   .|||.|.....|||.||.||||..|||... |.. ...|||  .|
MHKHEIYQLCHEVKEIFRQEPNMVEVEET-PTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFL

NRGNHEDFMMN---LRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISE----TTDLNLLHRVERNKMKSVLIPPTETNRDHDTD
.|||||. .||    .|||  |. .||  ..|||..|..|...|.|......|.||. |||.|.    |.... |.   . ....               
LRGNHECRHMNMWVQYYGFYDECKRKY--YHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQ---------------

SKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDP---------RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKP----EG
                      ....  ..|....|.|||||         .  .|. ||. ||...||||||... ..|..|.. ||.|.|..    .|
----------------------HPPQEPPDWGLMCDLLWSDPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDG

YEICHDG-----KVVTIFSASNYYEEGSNRGAYIKL----------CSGTTPRFFQYQVTK
||..||.     |..|||||.||. ...| .|..|.          ...  ..|.|.. ..
YEFWHDRDTRVHKLITIFSAPNYCDQCDNHAAVMKVNDHKVIQYKMDKNLKCHFVQFKPQM

Phosphatase PPEF1.AA Group.PPP.PD 75-456 36 9.80000000001e-129 419.4 In-house 10-341 (349) Show / Hide
Range on Protein: 75-456
Range on HMM: 10-341/349
Sequence Identity: 36% (139 aa)

KEELELRNQSLEsEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIqTSPskeVTICGDLH
|.. . .... | ..   .. . ..||.|.|||.||||.|.||.. .. |.|||||.. |.|..|||.| |.|..||..||.... ..|   .|.|||.|
kakaaakaeaee-kksevkklsdeesievedsytgprlsfkltpdlvkelveafkekkqleakevlelleeakellkkepnllev-eap---itvcGDih

GKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLhGKRILQILEEFYAWLPIG
|..|||. .|..||||...|.|.|.||.|||||.|.|....|..  |.||. ..|.|||||. ..| .|||..|. .|||  |..|.....| .|||. .
GqfdDLlrlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvygfyeevkskykk-geeiyelfqevFnwLPla

TIVDNEILVIHGGISE-TTDLNLLHRVERNKmksvlipptetnrdhdtdskhnK-VgvtfnahgriktngsptehltehEWEQIIDILWSDPRGKNGCFP
..|..||..|||.|. .|.|. ....||..                      .                         ......|.|||||. ..|. ||
alidekilcvhGGlspeltsldqirkierpl----------------------epp-----------------------kegllcdllWsdpeeqkgwkp

NTcRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKA
. ||.|..||||...|.|.|..|...||.||...||||.....|.||||||.||..|.||..|..|.    . ...|.. .|  
nk-RGvgfvFgpdavekflkknnldliiRahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskh

Phosphatase PPEF1.AA Subfamily.PPP5C.PD 88-304 40 9e-63 202.1 In-house 24-239 (346) Show / Hide
Range on Protein: 88-304
Range on HMM: 24-239/346
Sequence Identity: 40% (88 aa)

EQDMRDRWDyVDSIDVPDSYNGPRLQF-PLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYK
.. . .. | .... | |.|.||.|.   .|   .. ||| ||.|. ||  |.|..| |.|..||..| ...|... .|..|.|||.||.||. || .||
kksvvekld-lealtveddyegpkleeekitkefvkellelfkkqkklhkkyalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifel

NGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKlhgKRILQILEEFYAWLPIGTIVDNEILVIHG
||||.|||.|||||||||  |.|....|    |.|||...|.|||||   ||  |||. |. .||.   ....... | .|||.........||.|||. 
nGlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhesdnmnklyGfegevkakyt---ekvadlftevfnwlPlahvinekvlvvhG

GISETTDLNL--LHRVERNK
.. .. |  |....||.   
Glfsedgvtlddlrkidrna

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_6.PD 138-440 34 4.2e-54 173.4 In-house 5-257 (272) Show / Hide
Range on Protein: 138-440
Range on HMM: 5-257/272
Sequence Identity: 34% (89 aa)

YVLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDF
.|..| ..|||.|. . .  ... |   ...|||.||.  ||. .| |.| | . | |.| ||.||||..|.|....| .. .||.. | |||||  ..|
ellkllelakkvfkkqkslvevea-p---ikvcGdihGqysdllrlfdkggfppdan-ylflGdyvdrGrqslevillllaykvkfpnnffllrGnhece

MMNLRYGFTKEILHKYKLhgKRILQILEEFYAWLPIGTIVDNEILVIHGGISEttdlnllhrvernkmksvlipptetnrdhdtdskhnkvgvTFNAHGR
  ||| .|. ..||   .|. . ..| ...||. ..| . || .|||.|.....  ....   |..   |      ||.|||||  .   . .  || ..
ainrvyGfydevqrryks--trlyaafqevfnalpltalvsgrilcmhGGlsk----------------------------------------klksldq

IKTNGSPTEHLTEhewEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAY
 |||.  |.|.| .. ...|.|.   .|||   . |.|||||| .| ..  |  | .|.                                         
lrelkrpldskee---slaidllwsdpenavkgwaensrGvsvvfGedavkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaav

IKL
   
mkv

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_5.PD 139-292 38 8.5e-35 109.9 In-house 6-151 (274) Show / Hide
Range on Protein: 139-292
Range on HMM: 6-151/274
Sequence Identity: 38% (57 aa)

VLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM
.|||| ..|..|| .. . .... |   .||.||.||.||||. || . | ... . |.| ||.|||| .|.|. ..|. ||. .|| |||||   .|  
ilevlekikstlkplaallevea-p---itivGdihGqlddllrifnavGaapkvq-ylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkk

MNLRYGFTKEILHKYKlhgKRILQILEEFYAWLPIGTIVDNEILVIHGGISETT
||| .|. .|..   ... .  .. .. ||. ..|.. || .|||||.      
inklygfkeelkkkrq---eslykkfndvfselplcarvskrilcmhGGispkl

Phosphatase PPEF1.AA Subfamily.PPP1C.PD 139-302 32 4.5e-34 108.1 In-house 6-162 (271) Show / Hide
Range on Protein: 139-302
Range on HMM: 6-162/271
Sequence Identity: 32% (53 aa)

VLEVLFETKKVLKQMPNFTHIQTSpskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM
. ... ...... . | . .....    . |.||.||.  ||. .| |.| |.| | |.| ||.|||||.|.| ...| .  . ||....||||||   .
irklclkareiflsqpilleleap----lkivGdihGqyadllrlfekggfppesn-ylflGdyvdrGkqsletivlllaykikypenffllrGnhecas

MNLRYGFTKEILHKYKLhgkRILQILEEFYAWLPIGTIVDNEILVIHGGISET-TDLNLLHRVER
|  |||  |.  .|..   .. ... . . .||. .|||..|...|||.|   ..|. ..|..| 
inriygfydeckrryni---klwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriar

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_2.PD 152-303 34 7.4e-34 106.8 In-house 19-169 (281) Show / Hide
Range on Protein: 152-303
Range on HMM: 19-169/281
Sequence Identity: 34% (53 aa)

QMPNFTHIQTSpSKEVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILH
... . ...   .  ||. .||||.  ||  ||  |. |. .. |.| ||.||||..|.|....| .    ||. | | ||||||.   | |||  | |.
efsallrvdee-clpvtvvadlhgqsidllriflineapgisk-ylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvnttltygffdecle

KYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETT-DLNLLHRVERN
||. .|... . . . .  ||. ... . .| .|||||    .|. ....|| 
kyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierp

Phosphatase PPEF1.AA Subfamily.PPP4C.PD 140-301 32 4.7e-32 101.2 In-house 7-162 (271) Show / Hide
Range on Protein: 140-301
Range on HMM: 7-162/271
Sequence Identity: 32% (53 aa)

LEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMM
..  .....| .  | ..... |   ||.|||.||.. ||  .|  .|   |.| |.| |||||||..|.| ...| .  . ||. ..||||||   .  
kalcakareilveesnvqrvds-p---vtvcgdihgqfydllelfkvggdvpetn-ylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrqi

NLRYGFTKEILHKYKlhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISET-TDLNLLHRVE
 ||| .|.|.||     .. .   | . .|....|.|..|...|||.|   . |. .  ..  
tqvygfydeclrkyg--saevwryctevfdylslaaiidgkifcvhgglspsistldeirsid

Phosphatase PPEF1.AA Subfamily.PPP5C.PD 354-452 48 3.7e-31 98.1 In-house 245-343 (346) Show / Hide
Range on Protein: 354-452
Range on HMM: 245-343/346
Sequence Identity: 48% (47 aa)

EQIIDILWSDPRGKNGCFPNtCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL-CSGTTPRFFQYQ
.....|||||. .||  |   || |..||||||.| |.. .|...||||| | ||||. ||||..|.||| || .. .|.||.|.|  ..|.| ...   
glllellwsdpqeanGrsps-krGvgiqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkfktfe





Phosphatase PPEF1.AA Subfamily.PPP3C.PD 136-304 31 2.2e-30 95.7 In-house 3-164 (292) Show / Hide
Range on Protein: 136-304
Range on HMM: 3-164/292
Sequence Identity: 31% (54 aa)

AHYVLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHE
.. .|... |. |.||. ... .... |   .|..||.||.  ||. .|  .| |.. . |.| ||.||||  |||... |    . ||.|.| ||||| 
eesalkiieeaakllkkeetllevea-p---itviGdihGqfydllklfevgGkpastk-ylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhe

DFMMNLRYGFTKEILHKYKlhgKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHRVERNK
 ..   . | .|. .||.   ... . | | .  ||. ...... | .|||.| | ..|. .....| | 
crhlteyftfkeevkikys---eevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfk

Phosphatase PPEF1.AA Subfamily.PPP6C.PD 158-303 36 1.1e-28 90.1 In-house 22-164 (271) Show / Hide
Range on Protein: 158-303
Range on HMM: 22-164/271
Sequence Identity: 36% (53 aa)

HIQTSpSKEVTICGDLHGKLDDLFLIFYKNGLPSERnPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLhg
.|.  |  ||.|||.||.. ||  .| . |   .   ||| |||||||  |.| .  | .  . ||. . | |||||   .   ||| .||.||      
nvqpv-sspvtvcgdihgqfydleelfrtggqvpdt-syvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqitqvygfydeclnkygn--

KRILQILEEFYAWLPIGTIVDNEILVIHGGISET-TDLNLLHRVERN
  . . . .  |.|..|.|...| .|||.|   . |. .. .||.  
anawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirviera

Phosphatase PPEF1.AA Subfamily.PPP2C.PD 145-294 34 2.7e-28 88.9 In-house 12-155 (271) Show / Hide
Range on Protein: 145-294
Range on HMM: 12-155/271
Sequence Identity: 34% (51 aa)

ETKKVLKQMPNFTHIQTSpskeVTICGDLHGKLDDLFLIFyKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYG
..|..|..  |  ....     ||.|||.||.. ||. .| . |  |    |.| ||.||||  |.| . .| .  . |.. . . |||||.   |||  
kakeilskesnvkevkcp----vtvcgdvhgqfhdllelf-riggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqitqvyg

FTKEILHKYKlhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD-L
| | ||      . ... ... .||. ..|||.|...|||.| . | |   
fydeclrkyg--nanvwkyftdlfdylpltalvdnqifclhgglspsidtl

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_4.PD 139-291 32 2.3e-27 85.9 In-house 6-150 (271) Show / Hide
Range on Protein: 139-291
Range on HMM: 6-150/271
Sequence Identity: 32% (48 aa)

VLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM
. .|..|..... .  ....|.. |   . . ||||.. .||  .|   | . |   .|| ||.||||...||.|..| .. |.. . | |||||   .|
iisvireaeaifsdekalveiea-p---ikvvgdlhaqfqdlirlfdllgrvpeek-lvflgdyvdrgpqgievlillfclkiryrdrivllrgnheias

MNLRYGFTKEILHKYklhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISET
 .||| .|  .||   |. .   ... .  ||| ... . .| .|||.|    
vnkkygfyeecvtky---geelwadfqrcfnrlpisaliakkvlcmhgglspe

Phosphatase PPEF1.AA Metallophos 165-407 16 2e-26 98.88 Pfam 1-124 (124) Show / Hide
Range on Protein: 165-407
Range on HMM: 1-124/124
Sequence Identity: 16% (40 aa)

KEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL
  ...|||.|| .||| ... . . . . . ..|.||.||||..|.| .. | . .. ||.  .. ||||..  .| .|||  |          ..    
MRILHCGDIHGQYDDL-NRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E----------NDW-MW

EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDP
 . . |.|   ..|  ||. ||..                                                                            
WWWF-WMPLA-LDDWKILCMHGPP----------------------------------------------------------------------------

RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKP
                         ..  .... .|| |. .|
-------------------------FCK-NGVDYVIRGHTHVP

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_7.PD 162-292 36 2.7e-26 82.2 In-house 25-166 (296) Show / Hide
Range on Protein: 162-292
Range on HMM: 25-166/296
Sequence Identity: 36% (51 aa)

SPSKEVTICGDLHGKLDDLFLIF----------YKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILH
. |  ||| ||.||. .||. |            | .|.  |. .|| ||.||||..||| . ..    ..||... | |||||   .|  |.|..|.  
eispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyillrGnhetkainfayefreelen

K-YKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETT
.  | .||.| .  .| ....|. ..| . || .|||||.  
rlskidgkeiyekfnevfsfmplaalvgekilcvhggispkl

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_3.PD 194-303 38 3.8e-25 78.6 In-house 93-200 (308) Show / Hide
Range on Protein: 194-303
Range on HMM: 93-200/308
Sequence Identity: 38% (42 aa)

NPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKlhgKRILQILEEFYAWLPIGTIVDNEILVIHGGISET-T
. |.| ||.||||  |||....|    |.||. ..| |||||   .| .||| .|. ..|.   ... ....  .  ||. ..|...|| .||||||  .
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrys---aalyeafqlafnvlplcavvnkkilcmhGGiseell

DLNLLHRVERN
||. |....| 
dlkqldklkrp

Phosphatase PPEF1.AA Subfamily.PPP2C.PD 355-452 36 1.4e-19 60.3 In-house 172-268 (271) Show / Hide
Range on Protein: 355-452
Range on HMM: 172-268/271
Sequence Identity: 36% (35 aa)

QIIDILWSDPRGKNGcFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQ
. |.|||||  ..| .  . || |  || |.. .. .. .|... |.|.   |||. .|| .||||||| ||     |..| ..|    .|.|..   
pmcdllwsdpddrgg-wgisprgagytfgkdiseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfd

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_5.PD 331-441 31 1.8e-18 56.4 In-house 150-260 (274) Show / Hide
Range on Protein: 331-441
Range on HMM: 150-260/274
Sequence Identity: 31% (33 aa)

TFNAHGRIKTNGSPTEHLTEHEwEQIIDILWSDPRGK-NGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYE
..   .|.   || .|. .|   ..|.||.||  . ..  .|  |.    ||  .  ..|.| ......|.|| . |||.| ..||.|||. |  | .| 
klksldslkalkkpttplacde-glqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysg

EGSNRGAYIKLC
|| ...      
edtnlgavvvvs

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_3.PD 356-439 33 3.2e-18 55.8 In-house 209-292 (308) Show / Hide
Range on Protein: 356-439
Range on HMM: 209-292/308
Sequence Identity: 33% (28 aa)

IIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIK
. |. |.||  .   . .. || |  ||..   . |.|..|....|.|.   .|||   | |.|||||| .|  .  | .|.. 
ladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavls

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_1.PD 150-291 24 4e-18 55.6 In-house 14-155 (273) Show / Hide
Range on Protein: 150-291
Range on HMM: 14-155/273
Sequence Identity: 24% (35 aa)

LKQMPNFTHIQTsPSKEVTICGDLHGKLDDLFLIFYKNGLPSErNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEI
|| . . . ..     .||..||. ..  ||. |.   | | | . ..| |...| || | | |.||  |   ||... . ||..|  ..     .  |.
lkiaeetslley-ieadvtviGdirsryadlldilkltGwPfe-qkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrligel

LHKYKLHG--KRILQILEEFYAWLPIGTIVDNEILVIHGGISET
  ..      . .  |. ..   ||. .... ..|....|.| .
rvrfpdsnkwralnaiikrllkrlPvaavlnkkllavysgvssn

Phosphatase PPEF1.AA Subfamily.PPP1C.PD 356-440 37 1.6e-17 53.8 In-house 172-256 (271) Show / Hide
Range on Protein: 356-440
Range on HMM: 172-256/271
Sequence Identity: 37% (32 aa)

IIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL
. |.|||||  .   . .  ||    || || .| |.|..|....|.|.   .|||. .. ..||.||| || .|  | || ...
lcdllwsdpdkevkgwgendrgvsftfgadvvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsv

Phosphatase PPEF1.AA Subfamily.PPP4C.PD 355-448 31 1.8e-16 50.1 In-house 172-264 (271) Show / Hide
Range on Protein: 355-448
Range on HMM: 172-264/271
Sequence Identity: 31% (29 aa)

QIIDILWSDPRGKNgCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRF
...|.|||||. .. ..  . || |  || ||...  .. ......|.|.   |||.   . ||.|..|| ||     |  | ..| . ..|  
plcdllwsdpedae-gwavsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdf

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_4.PD 355-440 33 1.8e-15 46.8 In-house 171-256 (271) Show / Hide
Range on Protein: 355-440
Range on HMM: 171-256/271
Sequence Identity: 33% (28 aa)

QIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL
.||.||.||  |   . .. || .  || .|  ..  . .....||.|.   .|||.    |..|.||. || .   | .|.||  
llidllwadpdnkveewkasirgisytfgkgvvedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkl

Phosphatase PPEF1.AA Subfamily.PPP6C.PD 355-438 32 7.6e-15 44.7 In-house 172-254 (271) Show / Hide
Range on Protein: 355-438
Range on HMM: 172-254/271
Sequence Identity: 32% (27 aa)

QIIDILWSDPRGKNgCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYI
. |..||||   .  .  . || |  ||  ||.....  .||...|.|.   ||..   | |.||..|| ||     |  . . 
afcdlvwsdpedve-twavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgniasil

Phosphatase PPEF1.AA Subfamily.PPP3C.PD 355-442 27 2.4e-14 43.1 In-house 171-271 (292) Show / Hide
Range on Protein: 355-442
Range on HMM: 171-271/292
Sequence Identity: 27% (28 aa)

QIIDILWSDPRGKN-------GCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHD------GKVVTIFSASNYYEEGSNRGAYIKLC
.. |.|||||  .           ||. ||  ....   ... |.| .|  .||.||.. .||.  ..        ..|.|||.|| .  .|..| .|. 
plcdllwsdpledygeeetseeflpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkye

S
.
n

Phosphatase PPEF1.AA PPP5 98-159 29 1.1e-12 44.06 Pfam 34-97 (97) Show / Hide
Range on Protein: 98-159
Range on HMM: 34-97/97
Sequence Identity: 29% (19 aa)

VDSIDVPDSYNGPRLQ-FPLTCTDIDLLLEAFK-EQQILHAHYVLEVLFETKKVLKQMPNFTHI
.......|.|.||||.   .| . .. ..| ||  |. || ...  .| ..|..||. |..  |
MENMTIEDDYDGPRLEDNKVTIEFMKDMMEWFKVQQKKLHKKCAYQILCQVKEILKKCPSLVDI

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_7.PD 356-441 32 5.6e-12 35.2 In-house 188-282 (296) Show / Hide
Range on Protein: 356-441
Range on HMM: 188-282/296
Sequence Identity: 32% (30 aa)

IIDILWSDP---------RGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLC
. |.|..||         . |     |. ||    |.    ... .|..||...|.|.  |||..   | |..|||||..|.|  |.|| .|.  
akdllfadpldvqllaavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesdnsgavlkve

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_2.PD 357-440 29 7.7e-10 28.0 In-house 179-266 (281) Show / Hide
Range on Protein: 357-440
Range on HMM: 179-266/281
Sequence Identity: 29% (25 aa)

IDILWSDPR-GKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHE----CKPEGYEICHDGKVVTIFSASNYYEEGsNRGAYIKL
|.|||||   ..  .  . ||    |.  |  |. .. .|....|.|.      ..|. .  .|..|..||| ||   . |. .||   
cdllwsdpektervgwslsargisfsfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsmk-ndssvlkl

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_1.PD 386-439 24 1.1e-07 21.4 In-house 202-255 (273) Show / Hide
Range on Protein: 386-439
Range on HMM: 202-255/273
Sequence Identity: 24% (13 aa)

VTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIK
.  ..|   .....|||..  .|||  . . ...|..||... ..  |||. . 
ivkellkatdmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvls

Efhand PPEF1.AA efhand 570-598 37 1.4e-07 32.21 Pfam 1-29 (29) Show / Hide
Range on Protein: 570-598
Range on HMM: 1-29/29
Sequence Identity: 37% (11 aa)

DLEIIFNAIDTDHSGLISVEEFRAMWKLF
.|. .|. .|.|..| |..|||..|.| .
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL

Phosphatase PPEF1.AA Subfamily.PPP_Nematode_3.PD 141-191 30 5.3e-06 15.7 In-house 8-54 (308) Show / Hide
Range on Protein: 141-191
Range on HMM: 8-54/308
Sequence Identity: 30% (15 aa)

EVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPS
|. . ..... . | . .... |   |||.||.||. .||  ..  || | 
elcyrarelfwkeplklelea-p---vtivGdihGqfedllalldlnGwpl

Sequence
Name Sequence Type Origin Length Description Download
PPEF1.AA Protein None 653 None Fasta, JSON
PPEF1.NA RNA None 1959 None Fasta, JSON
PPEF1.AA.PD_98-455 Protein Phosphatase Domain None 358 None Fasta, JSON