Gene PPEF2
PPEF2
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of PPEF2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | PPEF2.AA | Family.PPP.PD | 89-542 | 48 | 3.6e-148 | 483.3 | In-house | 16-342 (349) | Show / Hide |
Range on Protein: 89-542
Range on HMM: 16-342/349
Sequence Identity: 48% (172 aa)
TEDRFAQDSEMKKCSDYESIEVPDSYTGPRLSFPLLPDHATALVEAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVsTCYseeITVCGDLHGQLDDLI
.... ..||.||.||.|||||.||||||||||.|.||....|||||. |.||.|..||.||.|.|..| . ||...| ... ||||||.|||.|||.
kaeaeekksevkklsdeesievedsytgprlsfkltpdlvkelveafkekkqleakevlelleeakellkkepnllev-eap---itvcGDihGqfdDLl
FIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVhGKEILRTLQDVFCWLPLATLIDEKV
.|..||||..|..|.|.||.|||||.|||....|||..|.||..|.|.|||||...|| .|||..||..||| |.||....|.||.|||||.|||||.
rlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvygfyeevkskykk-geeiyelfqevFnwLPlaalideki
LILHGGVSD-ITDLELLDKIERSKivstmrcktrqksekqmeekrranqkssaqgpipwflpesrslpssplrlgsykaqktsrsssipcsgsldgrels
|..|||.|. .|.|. ..||||..| . ......|.|||||..|.|.|.|. ||.|..||||.....|.|.|....||.|
lcvhGGlspeltsldqirkierpl----------------------------------------------------------------------------
rqvrssvelelercrqqagllvtgekE-EpsrsaseadseagelrkptqeEWRQVVDILWSDPMAQEGCKANTiRGGGCYFGPDVTQQLLQKYNMQFLIR
|...|||||..|||..|||||.||.. .||..|..|....|. |||....|
--------------------------epp---------------------kegllcdllWsdpeeqkgwkpnk-RGvgfvFgpdavekflkknnldliiR
SHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVT
ahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhk
|
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| Phosphatase | PPEF2.AA | Subfamily.PPP7C.PD | 105-540 | 76 | 6.00000000001e-198 | 646.3 | In-house | 1-338 (338) | Show / Hide |
Range on Protein: 105-540
Range on HMM: 1-338/338
Sequence Identity: 76% (259 aa)
YESIEVPDSYTGPRLSFPLLPDHATALVEAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYV
||||||||||||||||||||.|....|.|||.||..|||.|||..|.||||.|.|||||.||||..|.|.||||||||.||||..|.|||||||.|..||
yesievpdsytgprlsfplllddveklleafklkkllhakyvllilretkkvlkqlpnisrvstaiskevtvcgdlhgklddlllilyknGlpsaenpyv
FNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSDITDLELL
||||||||||.|||||.||||..||||||..||||||||...||||||.|||..|||||||.|||.|.|||.|||||||||||.||.|||.||.||||||
fnGdfvdrGkesveillilfalllvypkevylnrGnhedyilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdktdlell
DKIERSKIVSTMRcktrqksekqmeekrranqkssaqgpipwflpesrslpssplrlgsykaqktsrsssipcsgsldgrelsrqvrssvelelercrqq
|||||||.||...|.|...||.||.|| .|.|.|||||..|||||||.||||||.||.||||.|||||||..||||||...||||||||||||||.||.|
dkiersklvsvlk---------------------------------------------------------------------------------------
agllvtgekeePSRSASEADSEAGELRKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVL
||||||||||||.|||||||||||..|||.||||||.|
-----------pprlkeeaesesgeekkltleewrqildilwsdpkaqeGckpntlrGgGsyfGpdvtkkllqkynlellirsheckpeGyefthnkkvl
TIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANK
tifsasnyyeeGsnrGayvklgkdltprivqyqask
|
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| Phosphatase | PPEF2.AA | Group.PPP.PD | 89-542 | 48 | 3.6e-148 | 483.3 | In-house | 16-342 (349) | Show / Hide |
Range on Protein: 89-542
Range on HMM: 16-342/349
Sequence Identity: 48% (172 aa)
TEDRFAQDSEMKKCSDYESIEVPDSYTGPRLSFPLLPDHATALVEAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVsTCYseeITVCGDLHGQLDDLI
.... ..||.||.||.|||||.||||||||||.|.||....|||||. |.||.|..||.||.|.|..| . ||...| ... ||||||.|||.|||.
kaeaeekksevkklsdeesievedsytgprlsfkltpdlvkelveafkekkqleakevlelleeakellkkepnllev-eap---itvcGDihGqfdDLl
FIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVhGKEILRTLQDVFCWLPLATLIDEKV
.|..||||..|..|.|.||.|||||.|||....|||..|.||..|.|.|||||...|| .|||..||..||| |.||....|.||.|||||.|||||.
rlfdinglppaenkylFlGDyVDRGkfsvEvilllfalkllypsrffllRGnhEsrsvnkvygfyeevkskykk-geeiyelfqevFnwLPlaalideki
LILHGGVSD-ITDLELLDKIERSKivstmrcktrqksekqmeekrranqkssaqgpipwflpesrslpssplrlgsykaqktsrsssipcsgsldgrels
|..|||.|. .|.|. ..||||..| . ......|.|||||..|.|.|.|. ||.|..||||.....|.|.|....||.|
lcvhGGlspeltsldqirkierpl----------------------------------------------------------------------------
rqvrssvelelercrqqagllvtgekE-EpsrsaseadseagelrkptqeEWRQVVDILWSDPMAQEGCKANTiRGGGCYFGPDVTQQLLQKYNMQFLIR
|...|||||..|||..|||||.||.. .||..|..|....|. |||....|
--------------------------epp---------------------kegllcdllWsdpeeqkgwkpnk-RGvgfvFgpdavekflkknnldliiR
SHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVT
ahevveeGyeffanrklvTifsapnYcgeysnkaavlkvdknlklsivqfkpskhk
|
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| Phosphatase | PPEF2.AA | PP2Ac | 141-540 | 26 | 2e-119 | 404.0 | SMART | 1-321 (321) | Show / Hide |
Range on Protein: 141-540
Range on HMM: 1-321/321
Sequence Identity: 26% (119 aa)
LHARYVLNLLYETKKHLVQLPNINRVS-TCYSEEITVCGDLHGQLDDLIFIF---YKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHL
.|. ... |..| |. . |.|| .|. | .. .|||||.|||.|||. .| .|||.|.|. |||.||.||||. |.|... ||.. ..||. |.|
MHKHEIYQLCHEVKEIFRQEPNMVEVEET-PTPPVTVCGDIHGQFDDLLRLFKKEDKNGKPPPYTNYVFLGDYVDRGPWSIECICLLFCYKICYPNNFFL
NRGNHEDHMVN---LRYGFTKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVS-------DITDLELLDKIERSKIVSTMRCKTRQKSEK
.|||||. ..| .||| |...|| ..|.|. .|..| |.||..||. |.|. |||.| .|. |. . .|.| .
LRGNHECRHMNMWVQYYGFYDECKRKY--YHKRIWKIFQECFSWMPLCALINNKILCMHGGLSPRECQTDHIHTLDDIRNIDRPQ---------------
QMEEKRRANQKSSAQGPIPWFLPESRSLPSSPLRLGSYKAQKTSRSSSIPCSGSLDGRELSRQVRSSVELELERCRQQAGLLVTGEKEEPSRSASEADSE
----------------------------------------------------------------------------------------------------
AGELRKPTQ-EEWRQVVDILWSDP---------MAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKP----EGYEFCHNR-----KVLTIF
..| . ..| . |.||||| ..|...|..||...||||||. . ..|.|.. ||.|.|.. .||||.|.| |..|||
----HPPQEPPDWGLMCDLLWSDPVDFQWFHDDQWVPGWQPNCMRGMSYYFGPDVVDEFCKKNNLDLIIRAHQCVQYQMMDGYEFWHDRDTRVHKLITIF
SASNYYEVGSNRGAYVKL----------GPALTPHIVQYQANK
||.||. ..| .|. |. . | .|.||.....
SAPNYCDQCDNHAAVMKVNDHKVIQYKMDKNLKCHFVQFKPQM
|
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| Phosphatase | PPEF2.AA | Subfamily.PPP5C.PD | 96-310 | 43 | 8.3e-63 | 202.2 | In-house | 24-238 (346) | Show / Hide |
Range on Protein: 96-310 Range on HMM: 24-238/346 Sequence Identity: 43% (93 aa) DSEMKKCSDYESIEVPDSYTGPRLSF-PLLPDHATALVEAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKN . . . | |.. | |.|.||.| . . . |.| |. ...|| .|.|..| |.|. | .|| . ... ...||||||.|||||. || .||| kksvvekldlealtveddyegpkleeekitkefvkellelfkkqkklhkkyalkilleakellkklpslveitipetkkitvCgdihgqfyDllnifeln GLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKvhgKEILRTLQDVFCWLPLATLIDEKVLILHGG ||.|..|.||||||||| |||....|..| |.||..|.|.||||| . .| |||. || .||. .... ...||.|||||..|.||||..|||. GlpseenpylfngDfvdrGsfsveviltllgfkllypnhfflsrGnhesdnmnklyGfegevkakyt---ekvadlftevfnwlPlahvinekvlvvhGG VSDITD--LELLDKIERS . . |. | ||.| lfsedgvtlddlrkidrn |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_6.PD | 173-310 | 42 | 1.4e-42 | 135.6 | In-house | 29-164 (272) | Show / Hide |
Range on Protein: 173-310 Range on HMM: 29-164/272 Sequence Identity: 42% (58 aa) EITVCGDLHGQLDDLIFIFYKNGLPsPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVhgKEILRTLQ |.||||.||| ||. .| |.| | |. |.| ||.||||. |.|....|.|. . .|..| | ||||| ...| ||| .|| ..|| ... ..|. pikvcGdihGqysdllrlfdkggfp-pdanylflGdyvdrGrqslevillllaykvkfpnnffllrGnheceainrvyGfydevqrryks--trlyaafq DVFCWLPLATLIDEKVLILHGGVSD-ITDLELLDKIERS || .|||..|. ...| .|||.|. ...|. | ...| evfnalpltalvsgrilcmhGGlskklksldqlrelkrp |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_2.PD | 155-315 | 42 | 1.2e-41 | 132.4 | In-house | 15-174 (281) | Show / Hide |
Range on Protein: 155-315 Range on HMM: 15-174/281 Sequence Identity: 42% (69 aa) KHLVQLPNINRVSTCySEEITVCGDLHGQLDDLIFIFYKNGLPsPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTK | ... . . ||. . .|| .||||| || || |. | . . |.| ||.||||..|||....|.|. ||. ||||||| | ||| | kaflefsallrvdee-clpvtvvadlhgqsidllriflineap-giskylflgdyvdrgrqsvevvllllaykhlypdhlfllrgnhedvnttltygffd EVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSD-ITDLELLDKIERSKIVST ..||. .|. . . . | | ||||.|| .||| .|||.| . .|| .||||| .| . eclekyndkgekvwlmiidafnhlplaalildkvlcahggisphlekledidkierplvvps |
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| Phosphatase | PPEF2.AA | Subfamily.PPP1C.PD | 146-311 | 37 | 2.4e-39 | 125.3 | In-house | 6-164 (271) | Show / Hide |
Range on Protein: 146-311 Range on HMM: 6-164/271 Sequence Identity: 37% (61 aa) VLNLLYETKKHLVQLPNINRVSTcyseEITVCGDLHGQLDDLIFIFYKNGLPsPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHM . .|. .... ... | . .... . ..||.||| ||. .| |.| | || .|.| ||.||||| |.| ...|.|. . ||..|.|||||| . irklclkareiflsqpillelea----plkivGdihGqyadllrlfekggfp-pesnylflGdyvdrGkqsletivlllaykikypenffllrGnhecas VNLRYGFTKEVMNKYKVHgkeILRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIERSK | ||| |. .|... . .|..|.| .||.|...|||....|||.| |...|| . .|.| inriygfydeckrrynik---lwktfvdcfnclpvaaivdekifcvhGGlspdlksleqirriarpt |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_5.PD | 172-306 | 42 | 3.9e-39 | 124.2 | In-house | 28-159 (274) | Show / Hide |
Range on Protein: 172-306 Range on HMM: 28-159/274 Sequence Identity: 42% (56 aa) EEITVCGDLHGQLDDLIFIFYKNGLPsPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKvhgKEILRTL . ||..||.|||||||. || . | . |. |.| ||.|||| .|.|. ..||.. . |||. || ||||| . .| |||.|...|.. ... .. . apitivGdihGqlddllrifnavGaa-pkvqylflGdyvdrGakslevslllfslkiaypkkvhllrgnhevkkinklygfkeelkkkrq---eslykkf QDVFCWLPLATLIDEKVLILHGGVSD-ITDLELLDK ||| ||| . .....| .|||.|. . |. | ndvfselplcarvskrilcmhGGispklksldslka |
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| Phosphatase | PPEF2.AA | Subfamily.PPP4C.PD | 146-312 | 40 | 4.7e-37 | 117.7 | In-house | 6-166 (271) | Show / Hide |
Range on Protein: 146-312 Range on HMM: 6-166/271 Sequence Identity: 40% (67 aa) VLNLLYETKKHLVQLPNINRVSTCyseeITVCGDLHGQLDDLIFIFYKNGlPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHM | .| .... ||. |..|| . .|||||.|||. ||. .| .| ||..|.| |||||||. ||| ...| |. . ||. .|||||| . vkalcakareilveesnvqrvdsp----vtvcgdihgqfydllelfkvgg-dvpetnylflgdfvdrgfysvetfllllalkvrypdritlirgnhesrq VNLRYGFTKEVMNKYKvhGKEILRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIERSKI ||| .|...|| |. | .|| .|.||..||.|....|||.| .|. |. . |.| . itqvygfydeclrkyg--saevwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqe |
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| Phosphatase | PPEF2.AA | Subfamily.PPP6C.PD | 161-313 | 41 | 6.5e-35 | 110.5 | In-house | 21-167 (271) | Show / Hide |
Range on Protein: 161-313
Range on HMM: 21-167/271
Sequence Identity: 41% (63 aa)
PNINRVSTcyseEITVCGDLHGQLDDLIFIFYKNGlPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKY
|.. ||. .|||||.|||. || .| . | |. |||| ||||||| |.| . |... . ||.. | ||||| . . ||| .|..|||
snvqpvss----pvtvcgdihgqfydleelfrtgg-qvpdtsyvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqitqvygfydeclnky
KVhgKEILRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIERSKIV
. . . .|| |..|..|||.|| .|||.| |.. |. . |||.. .
gn--anawkyctkvfdlltiaaiideqvlcvhgglspdvktldqirvieraqei
|
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_4.PD | 173-307 | 44 | 7.1e-35 | 110.5 | In-house | 29-157 (271) | Show / Hide |
Range on Protein: 173-307 Range on HMM: 29-157/271 Sequence Identity: 44% (59 aa) EITVCGDLHGQLDDLIFIFYKNGLPsPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYkvhGKEILRTLQ | | ||||.| .||| .| | . || .|| ||.||||. ..|.|..||.. . |... | ||||| || .||| .|.. || |.|. ..| pikvvgdlhaqfqdlirlfdllgrv-peeklvflgdyvdrgpqgievlillfclkiryrdrivllrgnheiasvnkkygfyeecvtky---geelwadfq DVFCWLPLATLIDEKVLILHGGVSDitDLELLDKI .| ||...|| .||| .|||.| .| ||.. rcfnrlpisaliakkvlcmhgglsp--elisldel |
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| Phosphatase | PPEF2.AA | Subfamily.PPP3C.PD | 147-311 | 37 | 1.2e-33 | 106.5 | In-house | 7-164 (292) | Show / Hide |
Range on Protein: 147-311 Range on HMM: 7-164/292 Sequence Identity: 37% (62 aa) LNLLYETKKHLVQLPNINRVSTcyseEITVCGDLHGQLDDLIFIFYKNGLPSpERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMV |... |. | | . ... .|.. |||.||.||| ||. .| .| |. . .|.| ||.|||| |.|... |.|. . ||....|||||| ... lkiieeaakllkkeetllevea----pitviGdihGqfydllklfevgGkpa-stkylflGdyvdrGyfsiecvlylyalkiaypsrlfllrGnhecrhl NLRYGFTKEVMNKYKvhgKEILRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIERSK . | .|| ||. .|. .| . | ||||.|...| | .|||.| .|..|. ..|..| | teyftfkeevkikys---eevyealmesfdslplaallnqkflcvhGGlspeikslddikkldrfk |
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| Phosphatase | PPEF2.AA | Subfamily.PPP2C.PD | 151-309 | 35 | 3.6e-33 | 104.9 | In-house | 11-163 (271) | Show / Hide |
Range on Protein: 151-309 Range on HMM: 11-163/271 Sequence Identity: 35% (57 aa) YETKKHLVQLPNINRVSTcyseEITVCGDLHGQLDDLIFIFyKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRY ..|. | . |.. |.. .|||||.|||. ||. .| . | ||. |.| ||.|||| ||| . .| |. . |.. . ||||| . || ekakeilskesnvkevkc----pvtvcgdvhgqfhdllelf-riggkspdtnylfmgdyvdrgyysvetvtllvalkvrykeritilrgnhesrqitqvy GFTKEVMNKYKvhGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSDIT-DLELLDKIER | |.. || .. . . |.| .|||..|.|.... ||||.| |. . ...| gfydeclrkyg--nanvwkyftdlfdylpltalvdnqifclhgglspsidtldkiraldr |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_7.PD | 170-310 | 39 | 9.9e-33 | 103.3 | In-house | 26-178 (296) | Show / Hide |
Range on Protein: 170-310 Range on HMM: 26-178/296 Sequence Identity: 39% (60 aa) YSEEITVCGDLHGQLDDLIFIF----------YKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNK | .|. ||.||| .||. | | .|. .. .|| ||.||||. |.| . ..||. ..||... | ||||| . .| |.|..|. |. ispPvtivGdihGqyeDLvriLnarvskeeakqksalsfvrkkfvfLGdYvdrGsksieCisLvfalkilyptkyillrGnhetkainfayefreelenr -YKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSD-ITDLELLDKIERS | .|||| ..||...|||.|. ||.| .|||.|. .. || ...||| lskidgkeiyekfnevfsfmplaalvgekilcvhggispklesledinsierP |
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| Phosphatase | PPEF2.AA | Metallophos | 172-492 | 14 | 8.9e-30 | 110.05 | Pfam | 1-124 (124) | Show / Hide |
Range on Protein: 172-492
Range on HMM: 1-124/124
Sequence Identity: 14% (47 aa)
EEITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHGKEILRTL
|..|||.|||.||| .. . . . . ..|.||.||||..| | .. ||.... ||. ... ||||... .| .||| | .. .
MRILHCGDIHGQYDDL-NRLFEII-E-KPDFVIFTGDYVDRGPWSDECIWLLFCYKMNYPGPVYWVRGNHDYMHGNDFYGFY-E----------NDW-MW
QDVFCWLPLATLIDEKVLILHGGVSDITDLELLDKIERSKIVSTMRCKTRQKSEKQMEEKRRANQKSSAQGPIPWFLPESRSLPSSPLRLGSYKAQKTSR
...| |.||| |.| |.|. ||..
WWWF-WMPLA-LDDWKILCMHGPP----------------------------------------------------------------------------
SSSIPCSGSLDGRELSRQVRSSVELELERCRQQAGLLVTGEKEEPSRSASEADSEAGELRKPTQEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDV
----------------------------------------------------------------------------------------------------
TQQLLQKYNMQFLIRSHECKP
... .. .|| |. .|
---FCK-NGVDYVIRGHTHVP
|
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_3.PD | 201-311 | 42 | 1.3e-29 | 93.2 | In-house | 93-201 (308) | Show / Hide |
Range on Protein: 201-311 Range on HMM: 93-201/308 Sequence Identity: 42% (47 aa) RSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVhgkEILRTLQDVFCWLPLATLIDEKVLILHGGVS-DIT . |.| ||.|||| |.|....|||. |.||. .| ||||| || .||| .|| ..|.. .. ..| .| |||......|.| .|||.| ... kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrysa---alyeafqlafnvlplcavvnkkilcmhGGiseell DLELLDKIERSK ||. |||..| dlkqldklkrpl |
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| Phosphatase | PPEF2.AA | Subfamily.PPP5C.PD | 439-538 | 43 | 2e-29 | 92.4 | In-house | 245-344 (346) | Show / Hide |
Range on Protein: 439-538 Range on HMM: 245-344/346 Sequence Identity: 43% (43 aa) RQVVDILWSDPMAQEGCKaNTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKL-GPALTPHIVQYQ .....||||| ..| . .. || |..||||||.. |.. |.. .||||| | ||||. |. |..|.||| || . .|.||...| ||.|.. ...| glllellwsdpqeanGrs-pskrGvgiqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlkpkfktfe A a |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_6.PD | 429-526 | 35 | 7e-20 | 61.2 | In-house | 160-258 (272) | Show / Hide |
Range on Protein: 429-526 Range on HMM: 160-258/272 Sequence Identity: 35% (34 aa) ELRKPTQEEW-RQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLG ||..|.... .|.||||| . |. || .. || |. ..||.| ......|.|. .|||| ..|..|||||.| . | | .|. elkrpldskeeslaidllwsdpenavkgwaensrGvsvvfGedavkkllekldidlvarahqvvqdGyeffaekklvtifsaphycgqfdnaaavmkvd |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_5.PD | 438-537 | 32 | 1.3e-19 | 60.1 | In-house | 171-271 (274) | Show / Hide |
Range on Protein: 438-537 Range on HMM: 171-271/274 Sequence Identity: 32% (32 aa) WRQVVDILWSDPMA-QEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQY .||.||.|| ... . | ||. || . .||.| ......|.|| . |||.| .....|.|||. | .||| |.. .| .|. . eglqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvl Q k |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_1.PD | 170-314 | 28 | 2.4e-19 | 59.6 | In-house | 26-172 (273) | Show / Hide |
Range on Protein: 170-314 Range on HMM: 26-172/273 Sequence Identity: 28% (39 aa) YSEEITVCGDLHGQLDDLIFIFYKNGLPsPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHG--KEI ..||.||. .. || |. | | .|. ..| |...| || |.| |.||. . |||.. . ||..| ..|. |. .. . . .. . ieadvtviGdirsryadlldilkltGwP-feqkilflGnlldsGkssleellillcskkcyPknvvilrGeyetelvksdrrligelrvrfpdsnkwral LRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIERSKIVS ||.|.... |.| ...||| | . . . ..| | naiikrllkrlPvaavlnkkllavysgvssnikekknvvavkrgiife |
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| Phosphatase | PPEF2.AA | Subfamily.PPP1C.PD | 432-528 | 34 | 9.2e-19 | 57.8 | In-house | 162-259 (271) | Show / Hide |
Range on Protein: 432-528 Range on HMM: 162-259/271 Sequence Identity: 34% (32 aa) KPTQ-EEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPA .||. .. ..|.||||| . .. || || || ...|.|.......|.|. .|||| ..|...|.||| || . | ||... rptdvpdkGllcdllwsdpdkevkgwgendrgvsftfgadvvekflkkhdldlivrahqvvedgyeffakrqlvtlfsapnycgefdnagavmsvdee |
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| Phosphatase | PPEF2.AA | Subfamily.PPP2C.PD | 441-538 | 34 | 1.3e-18 | 57.2 | In-house | 173-269 (271) | Show / Hide |
Range on Protein: 441-538 Range on HMM: 173-269/271 Sequence Identity: 34% (33 aa) VVDILWSDPMAQEGCKAnTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQA ..|.||||| . | . || | || |..... .. ..... |.|. |||...|.|.|.||||| || |..| ..| .|....|.. mcdllwsdpddrggwgi-sprgagytfgkdiseefnktngltlvsrahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddelkysflqfdp |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_3.PD | 441-526 | 33 | 5.3e-18 | 55.1 | In-house | 209-294 (308) | Show / Hide |
Range on Protein: 441-526 Range on HMM: 209-294/308 Sequence Identity: 33% (28 aa) VVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLG . |. |.|| |.. ... || | ||.. ...|.|.......|.|. .|||| .||..||||| .| | .|... ladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavlsvd |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_4.PD | 431-533 | 31 | 1.1e-17 | 54.2 | In-house | 161-264 (271) | Show / Hide |
Range on Protein: 431-533 Range on HMM: 161-264/271 Sequence Identity: 31% (32 aa) RKPTQEEWRQ-VVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPAL || .. | ..|.||.|| . ..||| . || .| .. .. .....||.|. .||| ||..|.||. || . | .| .|| .| pkpienldrgllidllwadpdnkveewkasirgisytfgkgvvedvckslevdliirahqvvqdgyevlsgrklitvfsvpnycaqfknaaavlkldenl TPHI .. eisl |
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| Phosphatase | PPEF2.AA | Subfamily.PPP4C.PD | 440-530 | 38 | 3.9e-17 | 52.3 | In-house | 172-261 (271) | Show / Hide |
Range on Protein: 440-530 Range on HMM: 172-261/271 Sequence Identity: 38% (35 aa) QVVDILWSDPMAQEGCkANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALT ...|.||||| .|| | . || | || ||..|. .. ......|.|. |||.. |.||||..|| || | | ..| .| plcdllwsdpedaegw-avsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeld |
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| Phosphatase | PPEF2.AA | Subfamily.PPP3C.PD | 440-541 | 26 | 4.4e-15 | 45.6 | In-house | 171-284 (292) | Show / Hide |
Range on Protein: 440-541 Range on HMM: 171-284/292 Sequence Identity: 26% (30 aa) QVVDILWSDPMAQ-------EGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHN------RKVLTIFSASNYYEVGSNRGAYVKLG .. |.|||||. . | . |..|| .... . ..||| .. .||.||.. .||. .. ..|.|||.|| .| .|..| .|. plcdllwsdpledygeeetseeflpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfpslitlfsapnyldvynnkaavlkye PAlTPHIVQYQANKV . .| ....... nn-vlnirkfncseh |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_7.PD | 429-525 | 28 | 1e-14 | 44.2 | In-house | 174-281 (296) | Show / Hide |
Range on Protein: 429-525 Range on HMM: 174-281/296 Sequence Identity: 28% (30 aa) ELRKPTQEEWR--QVVDILWSDPMA---------QEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGS ....| .| . |.|..||. . . |..|| |. ... .|.|.. ..|.|. |||..|..|.||||||..| . |. sierPlaevtedslakdllfadpldvqllaavsekpkyeknevrglsvvfneaavedvCrklnlklivrahqkipegfkffadkkLltifsaprymnesd NRGAYVKL || .|. nsgavlkv |
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| Phosphatase | PPEF2.AA | Subfamily.PPP6C.PD | 441-521 | 32 | 1e-14 | 44.3 | In-house | 173-252 (271) | Show / Hide |
Range on Protein: 441-521 Range on HMM: 173-252/271 Sequence Identity: 32% (26 aa) VVDILWSDPMAQEGCkANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGA ..|..|||| | | . || | || ||..... |.....|.|. ||... . |. |..|| || | . fcdlvwsdpedvetw-avsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnias |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_2.PD | 441-519 | 25 | 1.1e-08 | 24.3 | In-house | 178-261 (281) | Show / Hide |
Range on Protein: 441-519 Range on HMM: 178-261/281 Sequence Identity: 25% (20 aa) VVDILWSDPMAQEG-CKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHE----CKPEGYEFCHNRKVLTIFSASNYYEVGSNR |.||||| | . . || |. | ... .. ......|.|. ..|. . | .....||| || .. acdllwsdpektervgwslsargisfsfddivvekfcadndldlvvrahqlskemirqghklrangrlvslfsalnylsmknds |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_1.PD | 471-525 | 29 | 4.9e-08 | 22.5 | In-house | 202-256 (273) | Show / Hide |
Range on Protein: 471-525 Range on HMM: 202-256/273 Sequence Identity: 29% (16 aa) VTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKL . ..||. .|. .|||.. .||| |. . ...|..||... . |||. . . ivkellkatdmsvmirsnsvvreGylftlknrlitltsatklqkdynnrGvvlsi |
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| Efhand | PPEF2.AA | efhand | 656-684 | 31 | 6.6e-07 | 29.69 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 656-684 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) NLETIFRIIDSDHSGFISLDEFRQTWKLF |. .|...| |..|.|...||.. .| . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| Phosphatase | PPEF2.AA | Subfamily.PPP_Nematode_3.PD | 173-198 | 45 | 4.4e-06 | 16.0 | In-house | 29-54 (308) | Show / Hide |
Range on Protein: 173-198 Range on HMM: 29-54/308 Sequence Identity: 45% (11 aa) EITVCGDLHGQLDDLIFIFYKNGLPS .|..||.||| .||. .. || | pvtivGdihGqfedllalldlnGwpl |
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