Aque_g18552.t1_6
Species: A.queenslandica
Alias: Aque_g18552.t1_6
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: R_Sponge_1
Protein domain

Protein domains of Aque_g18552.t1_6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Fn3 Aque_g18552.t1_6.AA FN3 266-353 21 4.5e-11 44.04 SMART 1-69 (69) Show / Hide
Range on Protein: 266-353
Range on HMM: 1-69/69
Sequence Identity: 21% (21 aa)

PTAPVDD--IFFSSVESM------SITVSWDEVPCNGRNGPITGYYLTYTNITSNTSYTVNITGGNNRMYNLTGLIPY----TNYTVSIIPYNYNMNGPA
| .| ..  . ...| |       |.|.||..         |.||                        | .||| |.    |.|..... .| |..|. 
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG





Fn3 Aque_g18552.t1_6.AA FN3 365-444 22 3.4e-08 34.48 SMART 1-69 (69) Show / Hide
Range on Protein: 365-444
Range on HMM: 1-69/69
Sequence Identity: 22% (22 aa)

PGVISD---LRHA-RTPT------RINTVWNPPTIPNGIITVYEIRYRESTSTGPYNITNTTNTYYSIAGLIPN----TSYTIGVRAYTS--IGPG
||  ..   ||    |.|       ..  |.||          ...||                 | . || |.    | |.. |||...   |.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----------IVGYR-----------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Phosphatase Aque_g18552.t1_6.AA PTPc 640-870 22 2.2e-29 104.83 SMART 1-308 (308) Show / Hide
Range on Protein: 640-870
Range on HMM: 1-308/308
Sequence Identity: 22% (69 aa)

GLERIEEATYSTVMKPK--------KPVIEEFPS-----------DMTTEEGCQVLLKG---------------------YKEKKAFIIAESPMFNTARN
|.... |  ..  ....        .. . ..|            |    . . | ||                      |...|..| .  |. .|   
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWKMIDDRNVTAIVILCHENEN--------NQEVCYQYWPSTSIALVIGEYNITLLNENTNN-RYIERKFEVKNNNT--------GVKQSVTQFQITNWD
||.|. . ....|| || ..|.        ..| | ||||..   .. | . .|...|.. .  |. |.|||.| ..        . ...||... ||| 
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

STGEVKNPQTILMIIEEMYRTQRKRGN------------------TSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV--
  |  ..|. .| .|...  .|. ..|                  . ||||||. .||.. |||. . ... ..   .|.||..|. | | ||.|||   
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQ

-----VSVQLYLA
       .. |. 
YIFCYRCILEYIK

Phosphatase Aque_g18552.t1_6.AA Subfamily.R_Sponge_2.PD 677-864 34 1e-51 167.0 In-house 60-249 (262) Show / Hide
Range on Protein: 677-864
Range on HMM: 60-249/262
Sequence Identity: 34% (66 aa)

LKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPST-SIALVIGEYNITLLNENTNNRYIERKFEVKNNNT-GVKQSVT
. |||..||.| . .|. .|. .||.|. . .|. ||.|.  .||..|.| .|||..   .  .|....|| .|.. . || ||........ . .. ||
vdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvt

QFQITNWDSTGEVKNPQTILMIIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVS
||. ..| ...  |.  ..| .|... |.|.| ||..|.|.|||.|||.  |.|  . ... |.|..||||.|||. |....| ||... 
qfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaq

Phosphatase Aque_g18552.t1_6.AA Y_phosphatase 678-861 34 6.4e-50 176.73 Pfam 38-230 (243) Show / Hide
Range on Protein: 678-861
Range on HMM: 38-230/243
Sequence Identity: 34% (66 aa)

KG-YKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQ-EV-CYQYWPS--TSIALVIGEYNITLLNENTNNRYIERKFEVKNNNT--GVK
.| |...||.|..  || .|   ||.|. . ..|.|| || . |... |  |.||||.   .  ...| . .|. .|.... |. |.|||.| ..  . .
DGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQET

QSVTQFQITNWDSTGEVKN-PQTILMIIEEMYRTQRKRGNT--SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
..||... |||   |  .. |. .| .|...   |.. ..    ||||||. .||.. |||. . . ....||..|.||..|. | | ||.|||
RTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQT

Phosphatase Aque_g18552.t1_6.AA Subfamily.R_Anemone_2.PD 677-862 32 5.3e-46 148.3 In-house 63-247 (262) Show / Hide
Range on Protein: 677-862
Range on HMM: 63-247/262
Sequence Identity: 32% (61 aa)

LKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSiALVIGEYNITLLNENTNNRYIERKFEVKNNNTGVKQSVTQF
. ||..|||.| . .|. .| ..||.|. ..| . ||.| .|.|. .  . .||||.  .  .|. ...| .| . . |. |.|.||....  .. | ||
idGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWPskg-srsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqf

QITNWDSTGEVKNPQTILMIIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
..|.|  .|  ... ..| .. .. ..|.. |.. ||||||  |||  .|.|  . ... | |...||||..|  | |..  ||| 
hytsWpdegvpesgaslldlvrqvekaqqesgagpivvhcsaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtk

Phosphatase Aque_g18552.t1_6.AA Subfamily.R_Anemone_1.PD 675-862 27 2.8e-43 139.4 In-house 59-243 (258) Show / Hide
Range on Protein: 675-862
Range on HMM: 59-243/258
Sequence Identity: 27% (51 aa)

VLLKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPStsIALVIGEYNITLLNENTNNRYIERKFEVKNNNTGVKQSVT
. |.......|||....|. .|  .||.|. . ....||.|   .|.... | ||||.   .   ||....| ....   || |.. ......  .. |.
sylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnliegekkkchqYwPd--stekygelrvslrkkevfadyiirtlvlskkketeerevv

QFQITNWDSTGEVKNPQTILMIIEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|.. |.|   |  .. ...| . ... .. ...|....|||||. |||.  |..  . ... |.| |.|.|...|. | ..|  ||| 
qyhftvWpdkgvPqyatavLglrrkvqks-slagarpvvvhCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtk

Phosphatase Aque_g18552.t1_6.AA Subfamily.RA.PD 676-864 33 5.6e-43 138.2 In-house 62-253 (266) Show / Hide
Range on Protein: 676-864
Range on HMM: 62-253/266
Sequence Identity: 33% (61 aa)

LLKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIaLVIGEYNITLLNENTNNRYIERKFEVKNNNT----GVKQ
..||.||. || |. |. .|  .||.|| ... ..||.| . .| ..| |.||||.  . .  || .... .|.  . |  |.| |.. ... |.||  |
fidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqywpdeGl-vtyGeirvevkdetvledytvrdflvtqlpdatrekksr

SVTQFQITNWDSTGEVKNPQTILMIIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVS
.|   |   ... .| ..... ..|.. .| .||||||  |||.  |..  . ... |.|...|||...|. | |.|  |||           
lvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleq

Phosphatase Aque_g18552.t1_6.AA Subfamily.N_Choan_1.PD 677-870 28 1.1e-40 130.7 In-house 62-256 (262) Show / Hide
Range on Protein: 677-870
Range on HMM: 62-256/262
Sequence Identity: 28% (55 aa)

LKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIALVIGEYNITLLNENTNNRYIERKFEVkNNNTGVKQSVTQF
..|||..|..|....|. ..  .||.|. ...|.|||.. .| |...  |..|||  . .| .|.. .. |.|.....||||||......| ...|.|..
vpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWPdenselklgdvtvkslseeekktyierkfkl-eresgetreveql

QITNWDSTGEVKNPQTILMIIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV-IDVFQVLKSQRIQKPGSVQTVVSVQ-LYLA
 |.|  .|  .... .|   ........|. ....|.|||  |||.  . |  . .......   .|| .|... | ..   |||.|  . .|.| 
aytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvyka

Phosphatase Aque_g18552.t1_6.AA Subfamily.R_Ecdysozoa.PD 677-862 32 2e-40 129.7 In-house 63-254 (269) Show / Hide
Range on Protein: 677-862
Range on HMM: 63-254/269
Sequence Identity: 32% (64 aa)

LKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEvCYQYWPSTsIALVIGEYNITLLNENTNNRYIERKFEVKNNN---TGVKQSV
.||||||| ||.| .|. .|. .||.|| ...|| ||.| ...|.|.. | .|||        |. ...| .|.. . ||.|...| ...      .. |
ikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknrk-cakyWpie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkv

TQFQITNWDSTGEV-KNPQTILMIIEEMYRTQRKR----GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.|.. |.|.|  .| . ....| .||...  ...      .. ||||||  ||||..| | .  ....|.|  .|.|.. |  | |..  || .
vqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsl

Phosphatase Aque_g18552.t1_6.AA Subfamily.RG.PD 677-862 28 1.3e-39 127.2 In-house 63-249 (264) Show / Hide
Range on Protein: 677-862
Range on HMM: 63-249/264
Sequence Identity: 28% (54 aa)

LKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIALVIGEYNITLLNENTNNRYIERKFEVKNNNTGVKQS--VT
..||. .|..|..  |. .|. .||.|| ..|.. ||.| . .|. .. . .|||.   .| ......|||.... ..|. |.| .||...  ...  |.
idGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvr

QFQITNWDSTGEVKNPQTILMIIEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|.. |.|  .|  .     |. ..   .....  .  ||||.|  |||.....|  | ... ..|  ..|.||||  | ..|| |.| 
qyhytkWPdmgsPestlfvlifvkkeeaanke-eaGPivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtte

Phosphatase Aque_g18552.t1_6.AA Subfamily.RB.PD 677-864 27 1.3e-38 123.9 In-house 62-248 (261) Show / Hide
Range on Protein: 677-864
Range on HMM: 62-248/261
Sequence Identity: 27% (52 aa)

LKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIALVIGEYNITLLNENTNNRYIERKFEVKNNNTgvKQSVTQF
..||. .. .| .  |. .|  .||.|. ......||.| .  |. .| | .|||... . . |. ..|||.|.... .. |.|.......  |..|.|.
ipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgke--krkvrqy

QITNWDSTGEVKNPQTILMIIEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVS
. | |   |  ....|.| ..... .. .|.  .. ||||||  |||.  | |  . ... ... ..||| |. . | ..   ||| . 
hftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekq

Phosphatase Aque_g18552.t1_6.AA Subfamily.RK.PD 676-862 28 4.2e-38 122.1 In-house 63-252 (267) Show / Hide
Range on Protein: 676-862
Range on HMM: 63-252/267
Sequence Identity: 28% (54 aa)

LLKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHE-NENNQEVCYQYWPSTSIaLVIGEYNITLLNENTNNRYIERKFEVKN--NNTGVKQS
|. .||  .|||..  |. .| ..||... | | ..||.| .   |. .  |..|||  .     |. ...|.. .... .. | | |..   ... | |
lidsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyWPedte-vrygdikvelveaeldadlvvrifrveklargqeeire

VTQFQITNWDSTGE-VKNPQTILMIIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|| ..| .  .  .. ...| .| .. ..| . ..  |||||..  ||| .|.| .. ..  ..|||.|||.. |. | .|.  |.|    
vrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmvete

Phosphatase Aque_g18552.t1_6.AA Subfamily.N12.PD 676-862 31 9.4e-38 120.9 In-house 67-255 (270) Show / Hide
Range on Protein: 676-862
Range on HMM: 67-255/270
Sequence Identity: 31% (58 aa)

LLKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTS-IALVIGEYNITLLNENTNN-RYIERKFEVKNNntGVKQSV
..|| ..|...| | .|. .|  .||.||.. ||. .|..|.| |...  | .|||..   .| .||...|| .|.. .  .. | ..|.... ...|.|
fikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaq--kesrkv

TQFQITNWDSTGEVKNPQTILMIIEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTV
|. |.|   |  ......| .||.. ..|. . .. .|||||  |||    .|   . .  |.| .   .|||... . | |..|||     
yqfhytaWPDhgvPssaksllelielvrelqe-sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtk

Phosphatase Aque_g18552.t1_6.AA Subfamily.RC.PD 676-867 29 6.5e-35 111.8 In-house 80-278 (288) Show / Hide
Range on Protein: 676-867
Range on HMM: 80-278/288
Sequence Identity: 29% (57 aa)

LLKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWpsTSIALVIGEYNITLLNENTNNRYIERKFEVKNNNTGVKQSVTQ
...||. . .| |. |. .|  .||.|| .| |. ||.| . .| ..|.| .||         |. .. | ...  . || ||.|..|.. |||.| |.|
fidsykkpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrekcaeyw--eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtq

FQITNWDSTGEVKNPQTILMIIEEM--YRTQRKRG-------NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSVQ
   .  ..|. .| .|. .     |...         | ..|||.| ..|. .|.|  . ..  ..| ..|||||.|  | ..|. |..    .|     
iqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyi

L
 
l

Phosphatase Aque_g18552.t1_6.AA Subfamily.N23.PD 685-867 27 2.1e-34 110.1 In-house 148-340 (350) Show / Hide
Range on Protein: 685-867
Range on HMM: 148-340/350
Sequence Identity: 27% (52 aa)

AFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTS-IALVIGEYNITLLNENTNNRYIERKFEVKNNNTGVKQSVTQFQITNWDS
||.. .|. .|.  ||.|. .. .  ||.| .|.|.|.  | ||||     . . |.....| .... . .|||..... |..  ...|.....|.|   
pfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslkslrssegwiervlhlqhndvstvrlvchlhtttWse

TGEVKNPQTILMIIEE---MYrTQRKRGN------TSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQTVVSVQL
|  | |...| ...|   .| .|... .        |..|||  |||. .||   . |.. .  .|.|.. .|..  | |.  .||..| ..  
iGvPksPedllaflgevetay-aqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvilkk

Phosphatase Aque_g18552.t1_6.AA Subfamily.N3.PD 684-863 26 8.2e-34 108.0 In-house 69-247 (261) Show / Hide
Range on Protein: 684-863
Range on HMM: 69-247/261
Sequence Identity: 26% (48 aa)

KAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIALVIGEYNITLLNENTNNRYIERKFEVKNNNTGVKQSVTQFQITNWDS
. .|..  |. .|| .||.|. ....| ||.|    |. .  |.||||.|.  |  ||..... .|.... |. |.. .|...|  .....|.|..|   
nryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpd

TGEVKNPQTILMIIEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
|  .... .| ..|.. |. |.  .. .|||||  .||. .. .  |.. .  ..  . . ....  | |.   ||||  
hgvPddsadflefverv-rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtvs

Phosphatase Aque_g18552.t1_6.AA Subfamily.N5_RR.PD 676-863 29 9.1e-34 108.0 In-house 59-251 (265) Show / Hide
Range on Protein: 676-863
Range on HMM: 59-251/265
Sequence Identity: 29% (55 aa)

LLKGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIALVI---GEYNITLLNENTNNRYIERKFEVKNNNTgVKQ
.|||.| .||.. .  |. ||  .||.||  ..|. ||.| . .|.|.. | .|.| .  . .    |. .|.  . ...| |  ||. .|. .  |..|
yikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkyler-ver

SVTQFQITNWDSTGEVKNPQTILMIIEEMYRTQRKRGNT--SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
|. .  |.|  .   ....|.| ...|. ...... .    .|||||  .||  .| |.  .... . |.|.||...|... | |||       
svkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtse

Phosphatase Aque_g18552.t1_6.AA Subfamily.N6.PD 681-866 26 1.2e-32 104.4 In-house 94-284 (295) Show / Hide
Range on Protein: 681-866
Range on HMM: 94-284/295
Sequence Identity: 26% (49 aa)

KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIALVIGEYNITLLNENTNNRYIERKFEVKN-NNTGVKQSVTQFQIT
...| .| .. .. .|  .||.|. . | . ||.. .|.| ... |..|||...    .|....| ..|.....|. |.|.|.. ..   ....|.. ..
ehqkryiatqgcLkdtvsdFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfk

NWDSTGEVKNPQTILMIIEEMYRTQRK-RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVVSVQ
|   |  |.|...| ..|.. ..|.. . . .||||||. .||   |    . ..  ...|.   ||. ...|. | |. | |||...   
aWPdhgvpkdpgvvlnfledvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqyk

Phosphatase Aque_g18552.t1_6.AA Subfamily.N9.PD 677-861 29 2.5e-32 103.4 In-house 62-259 (275) Show / Hide
Range on Protein: 677-861
Range on HMM: 62-259/275
Sequence Identity: 29% (57 aa)

LKGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWP-STSIALVIGEYNITLLNENTNNRYIERKFEVKNNNTGVKQSVTQ
..|||.||||| .  |. .| ..||.|. ...|  ||.  .  |...  | |||| ..  .   |..... .. .... | .|..|.|| .|....|| |
vdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvth

FQITNWDSTGEVKNPQTILMIIEEMYRTQR---------KRG---NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
|.. |   |  .. ...| ..|.. ..|          ..|   .  ||||||  .||.  |..   .... ...|..||....|| |.  |.||   
fqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqt

Phosphatase Aque_g18552.t1_6.AA Subfamily.N13.PD 680-862 23 1.5e-29 94.3 In-house 62-244 (259) Show / Hide
Range on Protein: 680-862
Range on HMM: 62-244/259
Sequence Identity: 23% (42 aa)

YKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIA--LVIGEYNITLLNENTNNRYIERKFEVKNNNTGVKQSVTQFQ
...  .|..  |. .|...||.|. ..... |... .| |...  | .|||..      | . ....||. .  . .  |...||....|. |.... ..
gedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahln

ITNWDSTGEVKNPQTILMIIEEMYRTQRkrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|   |  .... .. .. |. . |.   .. ||||||  .||| .. .  . ..  . .  .|| ..... | |. | |||    
fvkwPdhgvPssaaelvqfvaevrllqt--dagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtk

Phosphatase Aque_g18552.t1_6.AA Subfamily.N_Choan_2.PD 678-867 24 2.1e-29 93.5 In-house 58-256 (266) Show / Hide
Range on Protein: 678-867
Range on HMM: 58-256/266
Sequence Identity: 24% (48 aa)

KGYK-EKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPST---SIALVIGEYNITLLNENTNNRYIERKFEVKNnnTGVKQSV
.|.. |||..| | .|. .| ..||.|| ...|||||.. . .|.... | .|||.     ..|  |. ... |.|. .. || ......   | .....
rGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlek--kgetrrl

TQFQITNWDSTGEVKNP------QTILMIIEEMYRTQRKRGN-TSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSVQ
 |. ..|   | ....      . .| ..... |....  . . ..||||. |||. .. |  ....  .....|| ....  | ...  ||...  .| 
vHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqye

L
 
l

Phosphatase Aque_g18552.t1_6.AA Subfamily.N1.PD 681-863 25 3.1e-29 93.3 In-house 64-254 (268) Show / Hide
Range on Protein: 681-863
Range on HMM: 64-254/268
Sequence Identity: 25% (48 aa)

KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIA--LVIGE--YNITLLNENTNNRYIERKFEVKNNNTGVKQSVTQF
. |. .|..  |. .||  ||.|. ..|  |...| .  |.||  |.||||. . .  |.. |  ....|. |.... .. |..|... .|. ...|. |
eakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhf

QITNWDSTGEVKNPQTILMIIEEMYRTQR-KRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVV
.|   |  . |...| .. .. ..   ..  ...|.|||  .|||. ..   | . .   .|    .|. .||   | .. | .||     
hyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpd

Phosphatase Aque_g18552.t1_6.AA Subfamily.RN.PD 683-866 29 5.8e-29 92.1 In-house 70-253 (264) Show / Hide
Range on Protein: 683-866
Range on HMM: 70-253/264
Sequence Identity: 29% (54 aa)

KKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIAlVIGEYNITLLNENT-NNRYIERKFEVKNNNTGVKQSVTQFQITNW
. |.| ...|. .|  .||.|. .. |. || |.. .|.. . |..||| .  . | . |.. |. |    . |. | | .|| .|   ..||||    |
apayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckrywpdeGse-vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflsw

DSTGEVKNPQTILMIIEEMYRTQRKRGnTSIVVHCSDTVGRSAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTVVSVQ
 ..|   .....|     . .. | |  ..||||||| .||. ....    ...  |    ||.   |.  | |.|| |.|    .
peegvPasaksllefrrkvnksyrGrs-cpivvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfe

Phosphatase Aque_g18552.t1_6.AA Subfamily.R_Nematode_2.PD 681-868 27 7.3e-29 91.8 In-house 66-250 (261) Show / Hide
Range on Protein: 681-868
Range on HMM: 66-250/261
Sequence Identity: 27% (52 aa)

KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPS-TSIALVIGEYNITLLNENT--NNRYIERKFEVKNNNT-GVKQSVTQF
...| ||.. .|. ||  .|| |.   .|  ||.||.  |...| | .|.|. ||  |..| ..|. .....  ...  .|...|....     ..|| .
gnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthy

QITNWDSTGevkNPQTILMIIEEMYRTqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVvsVQLY
| ..|   |    |.. . . | .  .  |. .  ||||||  .||.  | ...   .. ...  | .. ||  | ... ..||    ||| 
qyeeWpdrg---vPkshaelfeLlelv--kksekPivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkgiqte--sqly

Phosphatase Aque_g18552.t1_6.AA Subfamily.R_Nematode_3.PD 685-864 23 4.8e-27 86.0 In-house 66-254 (267) Show / Hide
Range on Protein: 685-864
Range on HMM: 66-254/267
Sequence Identity: 23% (45 aa)

AFIIAESPM--------FNTARNFWKMIDDRNVTAIVILCHENE---NNQEVCYQYWPST-SIALVIGEYNITL--LNENTNNRYIERKFEVkNNNTGVK
.|.. ||.         .|   ||.||.. .|...| ||  .|   ...| | .|.|      | .......    .......|...| . . . .  ||
klIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfveedgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkke

QSVTQFQITNWDSTGEVKNPQTILMIIEEMYRTqrKrgnTSIVVHCSDTVGRSAMFCAAATTINKCKTEG-VIDVFQVLKSQRIQKPGSVQTVVS
  ... |   .  ..|...| .|. .     |   |..|||||| ..||| . |.   .... ..   .|. ...|. | |..| .||       
ftvthllykgWkelnapeepkealelikfveks--k---tpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtele

Phosphatase Aque_g18552.t1_6.AA Subfamily.N14.PD 682-863 24 9.9e-26 81.6 In-house 68-261 (275) Show / Hide
Range on Protein: 682-863
Range on HMM: 68-261/275
Sequence Identity: 24% (47 aa)

EKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPST---SIALVIGEYNITLLNENTNNRYIERKFEVKNNNTGVKQSVTQFQI
... .|.| .|. .| ..||.|. ...|. ||.| .|.|. .| ...|.|..      .  |....|    .. ...| .....|   .. ...|  .| 
kersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqy

TNWDSTGEVKNPQTILMIIEEMYRTQRKRGN---------TSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
|.|   |  ..... |  .||.   .||  .           ..||||. |||. .   .   |.  ... .||. .||.  | |.|||.    
tDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtla

Phosphatase Aque_g18552.t1_6.AA Subfamily.N_Nematode_4.PD 683-863 24 6.1e-24 75.8 In-house 65-250 (264) Show / Hide
Range on Protein: 683-863
Range on HMM: 65-250/264
Sequence Identity: 24% (46 aa)

KKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIA-LVIGEYNITLLNENTN--NRYIERKFEVKNNN----TGV-KQSVT
|  .| .  |. .|  .|| |.    ....|.||.  |...| | .|.|..|    ..|.|.|||......     | . ..|| .    .   .  |  
kfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvk

QFQITNWDstgEVKNPQTILMIIEeMYRT-QRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
.|.. |    .   |..   .|. .|.. . |. .. ||||||  |||.| .     .  . .  .|.| ....  |  . ..||. .  
hvqvdwwr---dqvaPldaapvik-lykavkkkkkekPivvhcsaGvGrtatlvGidyatirirenseievldivrelramrlkavqshl

Phosphatase Aque_g18552.t1_6.AA Subfamily.N20.PD 682-863 26 3.4e-22 70.3 In-house 64-243 (257) Show / Hide
Range on Protein: 682-863
Range on HMM: 64-243/257
Sequence Identity: 26% (48 aa)

EKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWP-STSIALVIGEYNITLLNENTNNRYIERKFEVKNNNTGVKQSVTQFQITN
|.  .| .. |...|  .||.|. . |   | .. .| |     ||.||| |    | .  . . | | .  . .| | |.| ...||  .|||.|.|.|
eeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkkplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftk

WDSTGEVKNPQTILMIIeemYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVV
   |   . ....  |     ... .    .|||||  .||. .| .    .     .  .......   | |. | |||   
wpdhgtpasadsfikyi---ryarkshltgpmvvhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtke

Phosphatase Aque_g18552.t1_6.AA Subfamily.N_Nematode_1.PD 683-864 26 6.6e-21 65.8 In-house 66-252 (265) Show / Hide
Range on Protein: 683-864
Range on HMM: 66-252/265
Sequence Identity: 26% (49 aa)

KKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSI---ALVIGEYNITLlNENTNNRYIERKF------EVKNNNTG-VKQS
| || | .|. .|  .|| |.   .| |||.||.  |. .  | .|.|...     .  .. .||. ..... . .|..... . .|  ...||..| |.
pkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegeklefkekgqkitv-enslgvkkleedeevikvtvlevegaGektrk

VTQFQITNWDSTGEvknPQTILMIIEEMYRTQRKRgnTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQTVVS
|   |    |.. | ..| . ... ..  . ||||||  .||.    | .  ..|    .. |. ...|. | |.  |.|| .          
vthyqWtdWPdrGv---Ppadlaalelleavrgsk--gPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaq

Phosphatase Aque_g18552.t1_6.AA Subfamily.N_Nematode_5.PD 683-862 20 5.2e-18 56.2 In-house 63-243 (258) Show / Hide
Range on Protein: 683-862
Range on HMM: 63-243/258
Sequence Identity: 20% (37 aa)

KKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCyQYWP-STSIALVIGEYNITLLNENTNNRY-IERKFEVKNNNTGVKQSVTQFQITN
.| .|..  |  .|...||.|. . ..|..|.|....| ..  . ...| .|   | .|.  |.  . .....   | ..||.. . .  ..  ..|.| 
ekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketav-sffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhltt

WDSTGEVKNPQTILM-IIEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
     .. . ..   ||.. ... .  |...||...  .||...| .... |.. ...  ... ..||. | |.||.|...  
WkkkkvPdkvkkvikraiekvlskkqg-knapvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesl

Phosphatase Aque_g18552.t1_6.AA Subfamily.N_Nematode_6.PD 681-863 23 1.2e-17 55.2 In-house 60-239 (253) Show / Hide
Range on Protein: 681-863
Range on HMM: 60-239/253
Sequence Identity: 23% (43 aa)

KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPST-SIALVIGEY-NITLLNENTNNRYIERKFEVKNNNTGVKQSVTQFQI
.... .| ...|. .|  .|||||    |. ||.||.  |. .| . .| ...   | .|... ... ....  .. . |   .... .  |  ..  ||
tkprrlictqaplegtieefwkmilssgveyivmlcelvekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihW

TNWDSTGEVKNPQTILMIIEEMyRTQRKrgntSIVVHCSDTVGRSA---MFCAAATTINKCKTEGVIDVFQVLKSQRIQkpgSVQTVV
   |   . .. | ... . . ..|     ||||||  |||     .   .  .. . . .|| |..  |. .|..   .|||.|   
anWPdhGvPdsflsalrllsvv-kkdkk----PivvhCsaGvGrtGtlaliliilealrlpdfqgvkdllvklreerfr---avqtev

Phosphatase Aque_g18552.t1_6.AA Subfamily.N_Nematode_egg.PD 684-863 24 4.1e-15 46.9 In-house 69-243 (257) Show / Hide
Range on Protein: 684-863
Range on HMM: 69-243/257
Sequence Identity: 24% (45 aa)

KAFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENnqEVCYQYWPS---TSIALVIGEYNITLLNENTNNRYIER--KFEVKNNNtGVKQSVTQFQi
||.|..|. ||  .||.|.   .|  ||.|    |.  | |  |||     |. .| | ..|. |. ...   . |  |..   .   .. .  .|  ..
nefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyywpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgd-deelflehwq-

TNWDSTGEVKNPQTILmiieemyRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKtEGVIDVFQVLKS---QRIQKPGSVQTVV
. ...|  |  .|       |  |.   . .||.. . | ..| . |. ... .    | |. ||..    | ... ||..|.     
gdvnylsdvysplrvl-------rklrnl-skpvvvqdilGvskaatlvaieiallsll-rGpitkslvlravvflrlrrrlsvesvl

Phosphatase Aque_g18552.t1_6.AA Subfamily.N_Fungi_PTP1.PD 685-833 25 1.8e-14 44.5 In-house 103-284 (343) Show / Hide
Range on Protein: 685-833
Range on HMM: 103-284/343
Sequence Identity: 25% (45 aa)

AFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIAL-----------VIGEYNITLLN-----ENTNNRYIERKFEVKNNN--
.| . .|. .|  .|.|.|   .|. |. |  . |.| | ||.||.  |.             ..|  ...|       | ..|  . .  . .|||  |
kYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegsydditvklaskwenimgindsslysadvkkeasdndnksddndlnnnndl

TGVK------QSVTQFQITNWDSTGEVKNPQTILMIIE--------EMYR--TQRKRGnTSIVVHCSDTVGRSAMFCAAATTI
 |.        | |.|. ||   . . ||. || ..|         . .   . .|. ..|.|||||||  ....    .   
tpvtaavsepyevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnars-spilvhCsaGvGrtGtlvtlDsll

Phosphatase Aque_g18552.t1_6.AA PTPc_motif 772-874 27 3e-13 51.28 SMART 1-92 (92) Show / Hide
Range on Protein: 772-874
Range on HMM: 1-92/92
Sequence Identity: 27% (30 aa)

SVTQFQITNWDST-----GEVKNPQTILMIIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVSVQ
.|.... |||        |  .  . || .|...          .||||||. .||...|||. . ...      .|.||..|. | |.||.|||    .
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYI

LYLAYEDR
   .    
FCYRCILE

Phosphatase Aque_g18552.t1_6.AA Family.DSP.PD 694-882 10 8.6e-09 26.2 In-house 119-250 (387) Show / Hide
Range on Protein: 694-882
Range on HMM: 119-250/387
Sequence Identity: 10% (21 aa)

FNTARNFWKMiDDRNVTAIVILChenennqevcyqywpstsialvigeynitllN------EntnnryierkfevknnntgvKQSVTQFQItNWDSTgEV
. .| |. ..  . .||.|| |.                                      .                    .....  .| ..|. .. 
llaaknlewl-kelgvtkivnlt-------------------------------ddkpqftk--------------------elgikylri-pidDh-na

KNPQT-ILMIIEeMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTIN-KCKTEgviDVFQVLKSQRiqkpgSVQTVVSVQlYLAYEDRIMSDYSMI
...  .  .|.    ....  .  ..|||   .|||.. ..|    . ... |   . .. ..|.|     . .. .. . .|..  . ....    
pplenlfekaid-fieegnds-kgvVlVHCkaGkgRsgtliiaYlmksegltle---ealdwvrskR-----pgvitpnqg-flkqlkdlekeklkv

Phosphatase Aque_g18552.t1_6.AA Subfamily.N_Nematode_eak.PD 685-787 20 2.1e-07 21.5 In-house 69-170 (281) Show / Hide
Range on Protein: 685-787
Range on HMM: 69-170/281
Sequence Identity: 20% (20 aa)

AFIIAESPMFNTARNFWKMIDDRNVTAIVILCHENENNQEVCYQYWPSTSIALVIGEYNITLLNE-NTNNRYIERKFEVKNNNTGvkQSVTQFQITNWDS
.|..  .  .    ||.|. ...  ||| | .. |.. |   .|.|  .  |  | ....  .    .| .  |.....|      |  ...  |  |  
kyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevlkyGildverkeyavkrniletrllilrkGnet--hrvlhykvfGwte

TGEV
    
ttlp

Sequence
Name Sequence Type Origin Length Description Download
Aque_g18552.t1_6.AA Protein None 998 None Fasta, JSON
Aque_g18552.t1_6.NA RNA None 2994 None Fasta, JSON
Aque_g18552.t1_6.AA.PD_640-874 Protein Phosphatase Domain None 235 None Fasta, JSON