• Phosphatome.Net

Gene Aque_PTPRB-1

Aque_PTPRB-1
Species: A.queenslandica
Alias: Aque_g31713.t1, Aque_PTPRB-1
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: RB
Protein domain

Protein domains of Aque_PTPRB-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Fn3 Aque_PTPRB-1.AA FN3 83-164 16 5.4e-16 60.39 SMART 1-69 (69) Show / Hide 
Range on Protein: 83-164
Range on HMM: 1-69/69
Sequence Identity: 16% (16 aa)

PTSPSD---VSYINISST------SIEVSWNPPTDFNGPNEGYVITYIRLESDTESMSTNRLTGTSFVIENLEKY----EQYSVTVVAFTD--KGPG
| .|..   ..  ...||      |...||.||          ...|.                  .....|. .     .|...|.|...  .|.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----------IVGYR------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 Aque_PTPRB-1.AA FN3 179-265 19 4.2e-10 40.82 SMART 1-69 (69) Show / Hide 
Range on Protein: 179-265
Range on HMM: 1-69/69
Sequence Identity: 19% (20 aa)

PGPPSN---VSTM-STNT------SISITWSPPLDPNGLLLSYSINVTLNSTYAQYLSFDVMTMSVSQNIFSYTLFDLLPF----AGYDISLQASTS--V
||||.|   ..    |.|      |....|.||       ..|.                            ||. .| |       | ....| ..  .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------IVGYR----------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDA

GLG
| |
GEG
Fn3 Aque_PTPRB-1.AA FN3 279-381 14 1.3e-07 32.54 SMART 1-69 (69) Show / Hide 
Range on Protein: 279-381
Range on HMM: 1-69/69
Sequence Identity: 14% (17 aa)

PAAPVAN--PMASPVSST------AVNVSWLPPNLSNWNGLITNYTIEYRTNDEYIRPSIEVTATLSSFANSDDPRAATTPLQLESIIIPSLHEF----V
| .|  .  . ...|.||       |..|| ||            ...||                                     ... |..      
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP------------IVGYR------------------------------------YTVTGLKPGQYPWT

NYSFIITLSNS--IGQI
.|.| ..  |.   |. 
EYEFRVRAVNGNDAGEG
Fn3 Aque_PTPRB-1.AA FN3 396-480 17 9.1e-09 36.37 SMART 1-69 (69) Show / Hide 
Range on Protein: 396-480
Range on HMM: 1-69/69
Sequence Identity: 17% (17 aa)

SGPPLD---VSVIVDSPS------TARISWSPPMYIDRNGIIVNYTVRIITTVRGTIRETNISNVSGNYYDASDLPQF----ASFNVTVAAATS--VGLG
 ||| .   ..|   ...      ....||.||        ||.|.                       |  ..|          ...|.| ..  .| |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP--------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
Fn3 Aque_PTPRB-1.AA FN3 495-586 15 4e-13 50.84 SMART 1-69 (69) Show / Hide 
Range on Protein: 495-586
Range on HMM: 1-69/69
Sequence Identity: 15% (17 aa)

PSAPDP---VIVKRRNDT------AIQVNWTRPAEPNGIILGYLIYYIGTKNNTGTEYSNINVLIIINVTDPNTLSYLITNLLAD----TQYFINVTAYT
|..|     . |.  ..|       ... |..|           ..|.                            | .|.| ..    |.| . |.|..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP----------IVGYR----------------------------YTVTGLKPGQYPWTEYEFRVRAVN

S--AGLG
.  || |
GNDAGEG
Phosphatase Aque_PTPRB-1.AA Subfamily.N6.PD 879-1132 41 9.7e-81 262.7 In-house 12-290 (295) Show / Hide 
Range on Protein: 879-1132
Range on HMM: 12-290/295
Sequence Identity: 41% (114 aa)

FKFSEEYEKVS--AVGLDHSKDASLLPENRAKNRYTNILAYDHSRVKLESI-DDEPGSDYINANYI------------PGYR-MRRAYIATQGPLPSTFD
. |.||.|...  ..   .|.. .  .||..|||| ||| .||.||.|.   .. |||||||||||            .. . . . ||||||.|..|  
lgfweefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvs

DFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWPGAQ-PEVYGEINVDMLSETEKSDWIVRKFKIT---KEKRSRTITHYQFVSWPDHGVPDEAGPALDFV
||||| |..||.||||.|. ||||. || |||| ..  . .|.|.| ..||....|...|.|...   |.|..|.| .|.| .||||||| ..|  |.|.
dFWrmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfl

REVHEVASS--AFGPVIVHCSAGVGRTGTFIALGTLLQHIKDHDW---VDLFGLASEMRQHRNHMIQTEPQYVFIHKAM
..|.. ...    ||..||||||.||||||| . ..|. |. . .   .|.     ..|..|  ..||| || |.||. 
edvnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykav
Phosphatase Aque_PTPRB-1.AA PTPc 880-1137 39 5.69999999999e-136 458.93 SMART 1-308 (308) Show / Hide 
Range on Protein: 880-1137
Range on HMM: 1-308/308
Sequence Identity: 39% (124 aa)

KFSEEYEKVSAVGLDH---------SKDASLLPENR--AKNRYT-NILAYDHSRVKLESIDDE----PGSDYINANYIPGYRMRRAYIATQGPLPSTFDD
.|.||.|.  ... .          |.. . .||||   ||||. .|..|||.|||| ....|    .||||||||||.||. ...||.||||||.|..|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWRMTWEQNSHVIVMLTQLVER--------GRTKCHRYWPGAQPEVYGEINVDMLSETEKS-DWIVRKFKITKEKR----------SRTITHYQFVSWPD
|||| |.|..|.||||....|.        || |||.|||   |..|| | | ..||. .. |...|.|..|. ..          .||.|||.. .|||
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWPD

HGVPDEAGPALDFVREVHEVASSA-------------------FGPVIVHCSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQY
||||. . . |||.|.|... |.                     ||..||||||.||||||.|. ...|.|..   ||.|.. ..||..|..|.||| ||
HGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQY

VFIHKAMVDACK
.|..... . .|
IFCYRCILEYIK
Phosphatase Aque_PTPRB-1.AA Y_phosphatase 905-1134 45 3.9e-124 423.51 Pfam 1-243 (243) Show / Hide 
Range on Protein: 905-1134
Range on HMM: 1-243/243
Sequence Identity: 45% (112 aa)

NRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPG-YRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGR-TK-CHRYWPG---AQ
|. ||||..|..|||.|||| .|.....|||||||||.| |.  .|||.||||.|.|..||||| |.|....||||....|.||  | ||.|||     |
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

PEVYGEINVDMLSETEKSDWIVRKFKITKEKR----SRTITHYQFVSWPDHGVPDE-AGPALDFVREVHEVAS-SAFG--PVIVHCSAGVGRTGTFIALG
|..|| . | . ||....|..||.|..|. ..    .||.|||.. .|||||||.  . . |||.|.|... . .  |  |..||||||.||||||.|. 
PMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCAID

TLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVD
...|...... ||.|.. ..||..|..|.||| ||.|.......
IMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase Aque_PTPRB-1.AA Subfamily.RB.PD 880-1136 56 8.49999999999e-124 403.5 In-house 1-260 (261) Show / Hide 
Range on Protein: 880-1136
Range on HMM: 1-260/261
Sequence Identity: 56% (148 aa)

KFSEEYEKVSAVGLDHSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVML
.||||||....|| |....|. ...||||||.||||.||||||||....||...|||||||||||...| |||||||||.|.||||||.||..|..||||
rfseeyeelkkvgkdqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivml

TQLVERGRTKCHRYWPGAQ-PEVYGEINVDMLSETEKSDWIVRKFKITKEKRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASSA--FGPVIVHC
|||||.|..||..|||  . | .||.|.|..|.|.|...|..|.|||.|.|..|....|.|.||||||||... . |||||.|.| ....   .|..|||
tqlvEkgkekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgkekrkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHC

SAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDAC
||||||||||||| .|||.|...|.||.||. .|.|..||...||| ||.|||....| .
saGvGRtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldll
Phosphatase Aque_PTPRB-1.AA Subfamily.R_Anemone_2.PD 881-1135 51 1.9e-108 353.4 In-house 2-260 (262) Show / Hide 
Range on Protein: 881-1135
Range on HMM: 2-260/262
Sequence Identity: 51% (133 aa)

FSEEYEKVSAVGLD-HSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVML
.|||||..| .     . ...| | |.|||||.||||||..||||. ...|.||||||||||.||| ..||||||.||| |..||||| ||||| |||||
lseeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivml

TQLVERGRTKCHRYWPGAQPEVYGEINVDMLSETEKSDWIVRKFKITK--EKRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVA-SSAFGPVIVHC
||..|||..|.|||||. ... ||...|.. .|.| ||...|.||...  |. .|..  ... ||||.|||....  ||.||.|...  .|  ||..|||
tqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhc

SAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDA
||||||||.|||. .||..||.   ||.|.  ...|..|| |.||. ||.||......|
saGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvllea
Phosphatase Aque_PTPRB-1.AA Subfamily.N_Choan_1.PD 881-1135 44 8.3e-94 305.3 In-house 2-260 (262) Show / Hide 
Range on Protein: 881-1135
Range on HMM: 2-260/262
Sequence Identity: 44% (114 aa)

FSEEYEKVSAVGLDHSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLT
| |||||....|.|..  ||  .||. ||||.|| |||..|||..  ...  .||||||..|||.  ..|||||||.|.....||.| |||. ..|||.|
fieeyeklaeigvdntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvt

QLVERGRTKCHRYWPGAQ-PEVYGEINVDMLSETEKSDWIVRKFKI-TKEKRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASSAF-GPVIVHCS
. .| |. |||||||  .    .|.. | .|||.||. .| ||||. ...  .|.... ....|||||||...   |.| ..|... ..    |...|||
reieagklkChryWPdenselklgdvtvkslseeekktyierkfkleresgetreveqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCs

AGVGRTGTFIALGTLLQHIKDHDW-VDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDA
||||||||.||| .|.......   .|.  . .|.|..|| |.||  || |..||. ||
aGvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvykavlda
Phosphatase Aque_PTPRB-1.AA Subfamily.R_Anemone_1.PD 881-1135 42 1e-92 301.9 In-house 2-256 (258) Show / Hide 
Range on Protein: 881-1135
Range on HMM: 2-256/258
Sequence Identity: 42% (109 aa)

FSEEYEKVSaVGLDHSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLT
...|.....  . ...|...  .||..||||..|.|.||||| ||. .... |||||| |. ... .||.||||.||..|..||||| |.... ||||||
yaaefqrlk-eikeeekevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLt

QLVERGRTKCHRYWPGaQPEVYGEINVDMLSETEKSDWIVRKFKITKEKRS--RTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASSAFGPVIVHCSA
.|.|   .|||.|||  ..| |||..| . .. ...|.|.|.....|.|..  |....|.|..|||.|||..|   |...|.|..   .   ||.|||||
nliegekkkchqYwPd-stekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsa

GVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDA
||||||.|... ..|...| .  ||.|     .|..| ||.||. ||||||.|...|
GvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvfihlavlea
Phosphatase Aque_PTPRB-1.AA Subfamily.R_Sponge_2.PD 883-1135 42 2.3e-91 297.4 In-house 3-260 (262) Show / Hide 
Range on Protein: 883-1135
Range on HMM: 3-260/262
Sequence Identity: 42% (111 aa)

EEYEKVSAVGLDHSKDASLLPENRAKNRYTNILAYDHSRVKLESiDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQL
|| ||..    . | ... |.|| .|||...||.||.|||.|.. |....||||||... ||. | |||||||||..|..||||| ||.... |||||.|
eeeeksveketefslsiaklkenvgKnRfkeilpydmsRvrLrt-dgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnl

VERGRTKCHRYWPGA--QPEVYGEINVDMLSETEKSDWIVRKFKITKEKR---SRTITHYQFVSWPDHGVPDEAGPALDFVREV-HEVASSAFGPVIVHC
.|.|. ||..||| .  .   ||...| . .|.. .|.|.||.|..|||    ....|...||.||.|.||..|.. |.....| ..   |  ....|.|
eengkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvC

SAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDA
|.||||||||||| ..|...|  . .|.| .  ..| .|. ..|.. ||||||.|. ..
sdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdalley
Phosphatase Aque_PTPRB-1.AA Subfamily.RG.PD 881-1135 40 9.4e-90 292.0 In-house 2-262 (264) Show / Hide 
Range on Protein: 881-1135
Range on HMM: 2-262/264
Sequence Identity: 40% (105 aa)

FSEEYEKVSAVG-LDHSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVML
..|..|... .   | . ..|  .||. |||..||.|...|||||... .. |.|||||.|| |||  ..||.|||||..|..||||| ||.|...||||
leeqfeeiqklkpkdieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivml

TQLVERGRTKCHRYWPG-AQPEVYGEINVDMLSETEKSDWIVRKFKITKEK----RSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASSAFGPVIV
|.|.|.|| ....|||  ..|. .....| .||....|. .||.| . . |    ..|....|.. .|||.|.|. . . | ||.    . ... ||..|
tdldekgrrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivv

HCSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDA
|.||||||.||.||| ||||...... |......  .|..|.....|| |||||..|....
hdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel
Phosphatase Aque_PTPRB-1.AA Subfamily.RA.PD 881-1134 42 7.2e-86 279.2 In-house 2-263 (266) Show / Hide 
Range on Protein: 881-1134
Range on HMM: 2-263/266
Sequence Identity: 42% (112 aa)

FSEEYEKVSAVGLD-HSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVML
. ||..|...| .  .. ... ..||. |||. .|| ||.||| |  .. |. |||||| .| ||| .  .||.|||.  | .||||| |||.|. ||||
leeefkkltsvkiqkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativml

TQLVERGRTKCHRYWPGAQPEVYGEINVDMLSETEKSDWIVRKFKIT------KEKRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASSAFG-PV
|.| ||...||..|||      ||||.| .  ||.  |. ||.| .|      .||.|| .. . | |||. ||| |.   |.....|...     . |.
telkerkeekcaqywpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpi

IVHCSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVD
.||||||||||||||.| ..|. .|  . .|.|.  ...|. | .|.||. ||.||.|.. .
vvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle
Phosphatase Aque_PTPRB-1.AA Subfamily.N9.PD 882-1134 42 1.3e-84 275.3 In-house 3-272 (275) Show / Hide 
Range on Protein: 882-1134
Range on HMM: 3-272/275
Sequence Identity: 42% (114 aa)

SEEYEKVSAVGLDHSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQ
|.||... .       .|| |. |  |||||..| ||..||||...|... |||||||.. ||. ..|.|||||||. |..||||| |||.|||| |..|
skeyadirnepveGtflasklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttr

LVERGRTKCHRYWPGA--QPEVYGEINVDMLSETEKSDWIVRKFKIT--KEKRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASSA---F-----
|||| || .|||    . . .|...|  ..  ...|. ||...|.  |...||..||.||.||||.|||..|   ||....||  ..|   .        
vvergrlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdesk

-----GPVIVHCSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVD
   |..||||||.|||||||.|   |..... . ||..   . .|. | ..|||. ||.| ..|...   
ghlsgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
Phosphatase Aque_PTPRB-1.AA Subfamily.RK.PD 881-1136 37 3.7e-84 273.5 In-house 2-266 (267) Show / Hide 
Range on Protein: 881-1136
Range on HMM: 2-266/267
Sequence Identity: 37% (101 aa)

FSEEYEKVSAVGLDH---SKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEpGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIV
. ||.| . .|  .    . |......||.|||...|||||.|.|.| |.|..  ||||||..| .|.  .|.|.|||||..|  ||||. ...|.  ||
lkeefetlnsvtpelqsedcdiakkdrnreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv

MLTQL-VERGRTKCHRYWPGAQPEVYGEINVDMLSETEKSDWIVRKFKITK----EKRSRTITHYQFVSWPDH-GVPDEAGPALDFVREVHEVASS-AFG
|||.| ||.|| || .|||      ||.|.| ... . ..| .|| |...|     .  |.. ..||..||.. .||...   |...|.|... .    |
mlteldvevgrvkClkyWPedtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeG

PVIVHCSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDAC
...|||.|| ||.|||||. ..|. |. .. ||.|  . ..|...  |..|| ||.|.. ....|.
rivvhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvnmveteeqykfvydvileal
Phosphatase Aque_PTPRB-1.AA Subfamily.N12.PD 897-1136 43 2.6e-82 267.4 In-house 24-269 (270) Show / Hide 
Range on Protein: 897-1136
Range on HMM: 24-269/270
Sequence Identity: 43% (106 aa)

KDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWPG
..|.  .||..|||| .|| ||.|||.|. |..|.||||||||.| | . . .|||.|||||.| |||||| ||.| ...||. ..|| |..||.|||| 
teagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpe

A-Q-PEVYGEINVDMLSETEKS-DWIVRKFKITKEKRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASSAFGPVIVHCSAGVGRTGTFIALGTLL
  . .  .||..|.. .|   . |...| .|....| ||... ... .||||||| .| . |.....|.|. .|   |..|||||||||||| ||.    
egeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvr

QHIKD---HDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDAC
. .|.    . .|.| |  |.|..|. ..||. ||....||... .
ellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
Phosphatase Aque_PTPRB-1.AA Subfamily.R_Ecdysozoa.PD 880-1135 41 1.5e-80 261.7 In-house 1-267 (269) Show / Hide 
Range on Protein: 880-1135
Range on HMM: 1-267/269
Sequence Identity: 41% (110 aa)

KFSEEYEKVSA-VGLDHSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVM
|. |||||. | .  ..|  .|   ||  |||| .| |.|. ||||. |  .  ||||||..| ||. .. .|| |.|. .|.||||| .||....||||
kleeeyekLearleiskstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivm

LTQLVERGRTkCHRYWPGAQPEVYGEINVDMLSETEKSDWIVRKFKITKEK-----RSRTITHYQFVSWP-DHGVPDEAGPALDFVREVHEVASSA----
..| |  |  |..|||  .   ||.|.|.. || ..||.| |.....| |      || .. |...|. |  ||. |   |.....|.|. .        
lsnlteknrk-cakyWpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsg

-FGPVIVHCSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDA
.|..|||||||||.|.|.||  |||..|  | ||.|    ..|..||..|   ||||...|..|    
srsPivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyralady
Phosphatase Aque_PTPRB-1.AA Subfamily.N3.PD 896-1135 44 4.9e-79 256.6 In-house 17-259 (261) Show / Hide 
Range on Protein: 896-1135
Range on HMM: 17-259/261
Sequence Identity: 44% (111 aa)

SKDASLLPENRAKNRYTNILAYDHSRVKLESIDDepgsDYINANY----IPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCH
. .|. .||| ||||| .||.||. ||||.. .     |||||||    ||.  .   ||||||||..|  |||.|.|||.|..|||||.||||||.|||
aisaarkpenlaknryrdilpydatrvklkeset----dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkCh

RYWPGAQPEV-YGEINVDMLSETEKSDWIVRKFKITKEK--RSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASSAFGPVIVHCSAGVGRTGTFIA
.|||  . |. .||..| . .| |.. ...|.. .....  ..|.|.. |...||||||||..   |.||..|... |..  ||.||||||.|||| .|.
qyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlil

LGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDA
| | |. |  .. |    . ..||. |  ..||. || |. .|.. |
letalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailka
Phosphatase Aque_PTPRB-1.AA Subfamily.N5_RR.PD 891-1134 41 5.7e-79 256.6 In-house 9-262 (265) Show / Hide 
Range on Protein: 891-1134
Range on HMM: 9-262/265
Sequence Identity: 41% (104 aa)

VGLDHSKDASLLPENRAKNRYTNILAYDHSRVKLESI-DDEPGSDYINANYIPGYRM-RRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRT
. |..|..   .. .  ||||..||  ..||| |||   ... |.||||||| ||.   .||.|||||||.| .||||| ......||||||.| |. |.
lPlnfsqeelevfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrq

KCHRYWPGAQP----EVYGEINVDMLSETEKSDWIVRKFKITKEKR-SRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASS---AFGPVIVHCSAGV
||..|.| |.     | ||.... . . .|. |. |||. ... .| .|...|| . .|||| .||.. . ||.|.||.| ...     .||.||||||.
kcavyfPdaedyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGi

GRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVD
|||| |||    .......  ||.... ...|..|  |.||. || .||.|.. 
GrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
Phosphatase Aque_PTPRB-1.AA Subfamily.N_Choan_2.PD 904-1136 38 2.7e-73 237.8 In-house 20-265 (266) Show / Hide 
Range on Protein: 904-1136
Range on HMM: 20-265/266
Sequence Identity: 38% (94 aa)

ENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRM-RRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWPGAQPE--
|.. |||..||   ..||.||...... . ||||||..|.   ...|||..||||.|  .|||| ||.... |||.|.|.|.||.|| ||||  . |   
rnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekv

-V-YGEINVDMLSETEKSDWIVRKFKITKEKRSRTITHYQFVSWPDHGVPDEAG------PALDFVREVHEVAS--SAFGPVIVHCSAGVGRTGTFIALG
. .|.|.|  |||. .. .|... ...|.. .|...|.....||||||| |..        |. .|.|..| .  .  .|..||||||||||||.||. .
kladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiD

TLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDAC
 .. .. .  ||.  . .|.|..|  ..|.  || ...||.|. . 
iavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavveya
Phosphatase Aque_PTPRB-1.AA Subfamily.N13.PD 883-1135 38 1.1e-72 236.1 In-house 4-257 (259) Show / Hide 
Range on Protein: 883-1135
Range on HMM: 4-257/259
Sequence Identity: 38% (100 aa)

EEYEKVSAVGLDHSKDASLLPENRAKNRYTNILAYDHSRVKLEsidDEPGsdYINANYI--PGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLT
||....  .    . . .   ||..|||| |.| ||..||||.   || |  ||||..|  |    .  |||.||||| | .|||.| |||...||.|.|
eefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklg---degg--yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvt

QLVERGRTKCHRYWPGAQP---EVYGEINVDMLSETEKSDWIVRKFKITKE--KRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASsAFGPVIVH
. .|.|. |||||||  .     |.. ..|..|  ...... ||......   ..|| ..| .||.||||||| .| . . ||.||.....   ||..||
lekekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqt-dagPivvh

CSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDA
||||.||.|..|.. ..|. |. .  .|.  .  ..|. |. ..||. ||.|..||....
csaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailev
Phosphatase Aque_PTPRB-1.AA Subfamily.RC.PD 884-1134 34 8.5e-68 220.1 In-house 5-285 (288) Show / Hide 
Range on Protein: 884-1134
Range on HMM: 5-285/288
Sequence Identity: 34% (98 aa)

EYEKVSAVGLDHSKDASLLPENRAKNRYTNILAYDHSRVKL-------------------ESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDF
|....  |   ...  .  .||..||||...| ||. ||.|                   . || | ||.|||| .| .|.  . |||.||||  | |||
efqrlpsvrskrtikiarkeenksknrysdvlpydynrvelkhelemskesehdsdessdddidseegskyinasfidsykkpekyiaaqGplketvddf

WRMTWEQNSHVIVMLTQLVERGRTKCHRYWpGAQPEVYGEINVDMLSETEKSDWIVRKFKIT--KEKRSRTITHYQFVSWPDHGVPDEAGPALDFV----
||| .|.  .||||||.| |  | || .|| .   . ||...||.  .   ||.|.||...   |.| ||..|..|. ||.....|.|    |...    
wrmiferkvkvivmltelkeGdrekcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvk

------REVHEVASSAFGPVIVHCSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVD
      |...       .|..|||..|..|||.|||| .||. ..  . ||.|..  ..|. |  |...| ||.......|.
qklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyillydvlve
Phosphatase Aque_PTPRB-1.AA Subfamily.N1.PD 896-1135 39 2.6e-61 198.9 In-house 19-266 (268) Show / Hide 
Range on Protein: 896-1135
Range on HMM: 19-266/268
Sequence Identity: 39% (99 aa)

SKDASLLPENRAKNRYTNILAYDHSRVKLESIDDepgsDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWP
.. .. |||||..||| ..  |||||.|||. |     |||||. .   ...| || |||||| | | ||.| |||||. ..|| ..||....||. |||
etreaklpenrglnryrdvspydhsrikleradv----dyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikCaqywp

GAQPE---VYGE--INVDMLSETEKSDWIVRKFKITK--EKRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVA--SSAFGPVIVHCSAGVGRTGTF
  . |   .. |  ..| ..|| .|| ..||.....   ....|.|.|...  ||| |||.     |.|. .|.|    ||  ||...|||||.||.||.
qeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsagigrsgtl

IALGTLLQHIKDHDW---VDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDA
  . |.| .| ...    ||.     |.|..|  .|||  |  |   |... 
slvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiaileg
Phosphatase Aque_PTPRB-1.AA Subfamily.N14.PD 883-1134 34 1e-60 196.7 In-house 4-272 (275) Show / Hide 
Range on Protein: 883-1134
Range on HMM: 4-272/275
Sequence Identity: 34% (92 aa)

EEYEKVSAVGLDHSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEpGSDYINANYIPG--YRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLT
|||...   .|   ... ||||  |||. ..| |...||.| .  ..  ..||||  |       .| ||..||||. |  |||.| |||. ..|||||.
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken-stgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlt

QLVERGRTKCHRYWPGA----QPEVYGEINVDMLSETEKSDWIVRKFKIT--KEKRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVAS---SA---
  | |..|...|.|      .   .|. .|     .. .  | ...|.     |. ||. | |.. |||||||..  . |.|..||. |     |     
eeeedgkeksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnseves

----FGPVIVHCSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVD
     ||.|||||||||||  |    |.. ..  . .|.    . .|. | ...||  || |..|...  
vkeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlik
Phosphatase Aque_PTPRB-1.AA Subfamily.RN.PD 895-1134 40 1.3e-60 196.3 In-house 17-261 (264) Show / Hide 
Range on Protein: 895-1134
Range on HMM: 17-261/264
Sequence Identity: 40% (98 aa)

HSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRR-AYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRY
..|...  ..|  |||....|.||||||||..   .  ||||||  |     |. |||||||||.||  |||.| ||| . |||.||.| || ..|.|||
stkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnltrleeegvkqckry

WPGAQPEVYGEINVDMLSETEK-SDWIVRKFKI--TKEKRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVASSAFGPVIVHCSAGVGRTGTFIALG
|    |||.  .|...||     |..|| | .   . ...||.| . |.|||..||| .| . |.| | |         |..||||.|.||||..|..  
wpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilid

TLLQHI-KDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVD
.|... |    .|.      .|. |.....|. |. |. .|... 
lvlerllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
Phosphatase Aque_PTPRB-1.AA Subfamily.N23.PD 912-1135 33 3.6e-57 185.4 In-house 109-348 (350) Show / Hide 
Range on Protein: 912-1135
Range on HMM: 109-348/350
Sequence Identity: 33% (80 aa)

TNILAYDHSRVKLE-SIDDEPGSDYINANYIPGY-RMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWPGA--QPEVYGEINV
|.    |..||||. | . .  .||||| |.     |   .||||||..||  ||| | ||| | ||||||. ||....||..||| .  .....|...|
tpdsrhdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrv

DMLSETEKSDWIVRKFKITKEK--RSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVA-----S----SAFGPVIVHCSAGVGRTGTFIALGTLLQHI
 . |... . || |........    |...| .. .|...|||.  .  |.|. ||...      .     .  |.|.||||||||||||  . . .. .
slkslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysairel

KDHD-WVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVDA
. ..  ...  . ...|| | .|.|.. .. .. .|.. |
tagngiiniprvvrrlrqqRkymvqkkvilkklyeavlea
Phosphatase Aque_PTPRB-1.AA Subfamily.N_Nematode_1.PD 902-1134 34 6.5e-54 174.4 In-house 23-262 (265) Show / Hide 
Range on Protein: 902-1134
Range on HMM: 23-262/265
Sequence Identity: 34% (82 aa)

LPENRAKNRYTNILAYDHSRVKLEsiDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWPGAQPEV
... ||||...   |..||||.  ..   |||| |||.      . .| .|.|| .| .||| |   ..   |||| .|.|.|..||. |.| .. |.  
eaqeadknrykdvgcldknrvkla--eeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkkkcaeyfpakegek

--YGE----INVD---MLSETEKSDWIVR--KFKITK-EKRSRTITHYQFVSWPDHGVPDEAGPALDFVREVHevasSAFGPVIVHCSAGVGRTGTFIAL
. |    | |.     . .|... ...  .....   ...|..||||.  |||.|||||... .|.    .  ||..||||||.||||| .|.  .|...
lefkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdrGvPpadlaalelleavr----gskgPivvhCsaGiGrtGtivai

GTLLQHIKD-HDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVD
 . .   |   |  ..|..||. |||. ||.|.|. ...       
eyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvlln
Phosphatase Aque_PTPRB-1.AA Subfamily.R_Nematode_2.PD 903-1133 33 3.3e-51 165.5 In-house 27-257 (261) Show / Hide 
Range on Protein: 903-1133
Range on HMM: 27-257/261
Sequence Identity: 33% (75 aa)

PENRAKNRYTNILAYDHSRVKLesIDDEPGSDyINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWPGAQPE--
.. |.|| ..   ....|.   | |.  .. | ||..|     . .|||||||  |..||| |   ..   ||||.| ||. ..||..|.|  . .  . 
ylpkdkhRypdvPCkpetavev--ivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkl

VYGEINVDMLSETE--KSDWIVRKFKITKEKR---SRTITHYQFVSWPDHGVPDEAGPALdfvrEVHEVASSAFGPVIVHCSAGVGRTGTFIALGTLLQH
| ... ..|. .  | .  .|..|.....    .||.||||. .|||.|||.|. |..  .  |..||||||.|||..||.   | .... .. . |  .
dlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpdrgvPkshaelf----eLlelvkksekPivvhCsaGiGRtmafigteylare

IKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMV
  |.|.|| . |||| |. ... ...            
veadptieltealkelrehRwkgiqtesqlywltlgal
Phosphatase Aque_PTPRB-1.AA Subfamily.N_Nematode_4.PD 903-1134 30 1.4e-49 160.2 In-house 24-261 (264) Show / Hide 
Range on Protein: 903-1134
Range on HMM: 24-261/264
Sequence Identity: 30% (73 aa)

PENRAKNRYTNILAYDHSRVKLEsiDDEPGSDYINANYIPGYrMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWPGAQPE--
.|  ||||..||  |..|| |.  . .|  ||| |...     .  ||.|||||. | .||| | ...  .|.||| .|.||  || ||.|  . .  ..
eknsdknryadilcidetrvvlk--nrdpdndyihaswmrmP-dkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvv

VYGEINVDMLSETEK--SDWIVRKFKITKEK---RSR----TITHYQFVSWPDHGVPDEAGPALDFVREVHEvaSSAFGPVIVHCSAGVGRTGTFIALGT
|. .. .. ..|.  .| |.. .|.|. .    .      . |.|.  |.|.  | .| | ... . |..   .  .|..|||||||||| |.. .    
kfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkk--kkkekPivvhcsaGvGrtatlvGidy

LLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVD
..|..   ...  .  |.|. | . .|.. |..|.   ...  
atirirenseievldivrelramrlkavqshlqflfllvvlie
Phosphatase Aque_PTPRB-1.AA Subfamily.N_Nematode_6.PD 883-1133 30 1e-48 157.5 In-house 4-249 (253) Show / Hide 
Range on Protein: 883-1133
Range on HMM: 4-249/253
Sequence Identity: 30% (79 aa)

EEYEKVSAVGLDHSkdASLLPENRAKNRYTNILAYDHSRVKLEsiDDEpgSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQL
||....  . ...  |. . ... .||||||  .| .|.||.  |||    || ||..      | .| ||.|| .| ..||.|   . .. |||| .||
keykdspneasese--ataflkfkdrnrytniqCcdagrlkla--dde--dfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcel

VERGRTKCHRYWPGA--QPEVYGEINVDMLSETEKSDWIVRK--FKITKEKRS-RTITHYQFVSWPDHGVPDEAGPALDFVREVHevasSAFGPVIVHCS
|.|. |. .| .    .  .....   .  . .. | |. .   .|.|.      . |... .||||||||.   || ..  |.    .   |..|||||
vekgkeksaeylsdkvGdarkitklctvikigrkdidkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvvk----kdkkPivvhCs

AGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMV
|||||||.. . ..|. ..  |  ..  |   .|. | . .|||.||.. .. .. 
aGvGrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvl
Phosphatase Aque_PTPRB-1.AA Subfamily.N20.PD 902-1133 37 1.5e-47 153.8 In-house 23-253 (257) Show / Hide 
Range on Protein: 902-1133
Range on HMM: 23-253/257
Sequence Identity: 37% (90 aa)

LPENRAKNRYTNILAYDHSRVKLESiddepGSDYINANYIPGYRM--RRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWPGAQ-
| || |||| .|| || .|| |         |||||.||          |||||||| || ||||.|  |.|| || |.|. .| |  ||..||| .   
qpsnreknryrdilpydstrvplgk-----skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislk

-PEVYGEINVDMLSETEKSDWIVRKFKITKEK--RSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEvaSSAFGPVIVHCSAGVGRTGTFIALGTLLQH
|     . | .        .|.| |.. ..    |... . ||  ||||| |  |   . ..|  ..  |   ||..||||||.|||| |...  ..  |
kplelkhfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryark--shltgpmvvhcsagigrtgvflcvdvvfca

IKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMV
     .... . ..||..|. |.||. || | .  .. 
ivkncsfnimdivaqmreqrsgmvqtkeqyhfcydivl
Phosphatase Aque_PTPRB-1.AA PTPc_motif 1033-1134 40 4e-44 153.81 SMART 1-92 (92) Show / Hide 
Range on Protein: 1033-1134
Range on HMM: 1-92/92
Sequence Identity: 40% (43 aa)

TITHYQFVSWPDH-----GVPDEAGPALDFVREVHEVASSAFGPVIVHCSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVF
|..||.. .||||     |||.   . |.|.|.|..       |..||||||.||||||.|. ...|.      || |..  |||..|..|.||| ||.|
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIF

IHKAMVD
..... .
CYRCILE
Phosphatase Aque_PTPRB-1.AA Subfamily.R_Nematode_3.PD 884-1133 26 1.5e-38 124.1 In-house 5-263 (267) Show / Hide 
Range on Protein: 884-1133
Range on HMM: 5-263/267
Sequence Identity: 26% (67 aa)

EYEKVSAVGLDHSKDASllpENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPgYRMRRAYIATQGPL--------PSTFDDFWRMTWEQNSHV
..||.  ..   ... |   .. ...|..... . ..||.|.       .|.|.||..         | ||.|.|| . || |  .......||| . ||
afekiaklakknatsls---kkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveq

IVMLTQLVE---RGRTKCHRYWPGAQPEVY--GEINVDM--LSETEKSDWIVRKFKITKEK-RSRTITHYQFVSWPDHGVPDEAGPALDFVREVHEVAss
   ..  || .|.| .. ..   ....|     ..  . |   |....| |||.||... .|.....|.|. .||. .. |...      ||.||||.|.
vvmlcdfveedgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfekkkeftvthllykgWkelnapeepkealelikfveksk--

afGPVIVHCSAGVGRTGTFIALGTLLQHIKDHD-WVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMV
.|..|. |     | |  ..  .||  | .|.|..| . |||| .. |.   ..             
--tpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgil
Phosphatase Aque_PTPRB-1.AA Subfamily.N_Nematode_5.PD 882-1134 23 9.5e-37 118.0 In-house 3-255 (258) Show / Hide 
Range on Protein: 882-1134
Range on HMM: 3-255/258
Sequence Identity: 23% (62 aa)

SEEYEKVSAVGLDHSkDASLLPENRAKNRYTNILAYDHSRVkleSIDDEPgSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQ
..|.||.... ...  . .   .|  |||....  .|..||   .  ||. ..||||..|    ... .| || |||.|  |||||  ... . .|.|..
ktefeklaslkpnke-tckafeknlkknrskdvkilDetrV---kltded-dsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllve

LVERGRTKChRYWP--GAQPEVYGEINVDMLSETEKSDWIvRKFKI--T--KEKRSRTITHYQFVSWPDHGVPDEAGPALDfvREVHEVASSA---FGPV
  |  .|..  ..|    .   .|.. . .   ..|.|    ....     .   |  ...|..|... |||.  ...   |....|.|.      ||.|
deelketav-sffpletgdylnlgkmfinnrkvevkedek-keytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvik--raiekvlskkqgknapv

IVHCSAGVGRTGTFIALGTLLQHIKDHDWVDLFGLASEMRQHRNHMIQTEPQYVFIHKAMVD
....|.||.|||..| .  . ...   ...  .  ..|. | .....  ||.....|..|  
vvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavld
Phosphatase Aque_PTPRB-1.AA Subfamily.N_Nematode_egg.PD 895-1132 25 3.6e-29 93.4 In-house 16-252 (257) Show / Hide 
Range on Protein: 895-1132
Range on HMM: 16-252/257
Sequence Identity: 25% (61 aa)

HSKDASLLPENRAKNRYTNILAYDHSRVKLESIDDEPGSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERgrTKCHRYW
|   ..  ... | |   .   . ||||||        |.| ||.. |  .   .| .| ||  | .||||| .... .|||||  .|    .|. ||| 
islttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyyw

PGAQPE--VY--GEINVDMLSETEKSDWIV--RKFKI-TKEKRSRTITHYQFvswpDHGVPDEAGPALDFVREVHEVASsafgPVIVHCSAGVGRTGTFI
|. |  |.  | .... |   .|.| .    |.|.   ..  . . |.|     |.    |  .| . ...     ||.|..  || ...|..|. . | 
pkaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelflehwqg----dvnylsdvysplrvlrklrnlsk----pvvvqdilGvskaatlv

ALGTLLQHIKDHDWV-DLFG-LASEMRQHRNHMIQTEPQYVFIHKAM
..     .  |       .|..|.  ...  .|.|... .       
aieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlv
Phosphatase Aque_PTPRB-1.AA Subfamily.N_Fungi_PTP1.PD 904-1009 42 4.7e-29 92.8 In-house 44-160 (343) Show / Hide 
Range on Protein: 904-1009
Range on HMM: 44-160/343
Sequence Identity: 42% (51 aa)

ENRAKNRYTNILAYDHSRVKLE-S------I-DDEPGSDYINANYIP----GYRMRRA--YIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTK
|  |||||.||| |.||||||. |      .     ..|||||||.     . ..     |||||.|||||.|||...  .. .||..||..|| .. ||
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek

CHRYWPGAQpevYGEINVDM
.|||.  .   | .|.| . 
cyrYWqegs---ydditvkl
Phosphatase Aque_PTPRB-1.AA Subfamily.N_Nematode_eak.PD 904-1049 26 2.5e-16 51.2 In-house 25-171 (281) Show / Hide 
Range on Protein: 904-1049
Range on HMM: 25-171/281
Sequence Identity: 26% (39 aa)

ENRAKNRYTNILAYDHSRVKLESIDDEPgSDYINANYIPGYRMRRAYIATQGPLPSTFDDFWRMTWEQNSHVIVMLTQLVERGRTKCHRYWPGAQPE-VY
|.  .||  .|. .|.  |.| |   ..   ||||  .    . | || |  .  .    ||.|  ||.|  ||.| . || .  |  .|.|    .  |
eavnrnrvvkivpqdrylvrltssqlnr-dGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledveekleksdkyfpdktevlky

GEINVDMLSE-TEKSDWIVRKFKITKEKRSRTITHYQFVSWPDHGVPD
| ..|.  .   ...   .|.....|   .  . ||..  | .  .| 
GildverkeyavkrniletrllilrkGnethrvlhykvfGwtettlpk
Phosphatase Aque_PTPRB-1.AA Subfamily.N_Fungi_PTP1.PD 1065-1132 30 2e-12 38.1 In-house 256-338 (343) Show / Hide 
Range on Protein: 1065-1132
Range on HMM: 256-338/343
Sequence Identity: 30% (25 aa)

ASSAFGPVIVHCSAGVGRTGTFIALGTLLQ------HIKD-----HDWVDLFG----LASEMRQHRNHMIQTEPQYVFIHKAM
..   |..||||||||||||...|  ||.      ....     . .  ..     .  |.|..|  |.|.  |..||..|. 
dnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeal
Phosphatase Aque_PTPRB-1.AA Family.DSP.PD 1014-1089 21 2.2e-10 31.8 In-house 123-205 (387) Show / Hide 
Range on Protein: 1014-1089
Range on HMM: 123-205/387
Sequence Identity: 21% (19 aa)

EKSDWIvRKFKI----------TKEKRSRTITHYQFvSWPDHGVPDEAGpaLdFVREVHeVASS---AFGPVIVHCSAGVGRTGTFIAL
....|  .. ..          .... .  |..... ...||..|. .   | |.. .  . ..   . | | ||| ||.||.|| |. 
knlewl-kelgvtkivnltddkpqftkelgikylri-pidDhnapplen--l-fekaid-fieegndskgvVlVHCkaGkgRsgtliia
Phosphatase Aque_PTPRB-1.AA Subfamily.PTPDC1.PD 1031-1128 30 3.4e-09 27.9 In-house 132-220 (229) Show / Hide 
Range on Protein: 1031-1128
Range on HMM: 132-220/229
Sequence Identity: 30% (29 aa)

SRTITHYQFvSWPDHGVPDeAGPALDFVREVHEVAssAFGPVIVHCSAGVGRTGTFIALGTLlqHIKDHDWVDlfgLASEMRQHRNHMIQTEPQYVFI
. |..|.| ...|.||.     .|| |. |  .     | . ||| || ||||  ||   .  . |. .  .     . .|..| .|||  |  ..  
rqgiyfynf-glkDygvas-leriLdivkvvdfal--eegkiavHCHAGlGRtGvliacylv--yakrltaee---aiklvrskrpksiqtreqvelv
Phosphatase Aque_PTPRB-1.AA Subfamily.DSP23.PD 1038-1124 29 3.2e-08 25.1 In-house 32-116 (128) Show / Hide 
Range on Protein: 1038-1124
Range on HMM: 32-116/128
Sequence Identity: 29% (26 aa)

QFVSWPDHGVPDEAGPALDFVRE---VHEVASSAFGPVIVHCSAGVGRTGTFIALGTllqhIKDHDWVDLfGLASEMRQHRNHMIQTEPQ
. ...   ..||   |||. | .   . |.|    ..| |||  |.|||||..|       .| ..         |.|..|.  |.||  
psltlrridipdfcPPaleqvarlvriveeaekkeeavgvhcalGlGrtGtllacyl----vkeeglaad-daiaevrkrrkGsietveq
Phosphatase Aque_PTPRB-1.AA Subfamily.CDC14.PD 1049-1088 40 1.6e-07 22.7 In-house 178-217 (258) Show / Hide 
Range on Protein: 1049-1088
Range on HMM: 178-217/258
Sequence Identity: 40% (16 aa)

DEAGPALDFVREVHEVASSAFGPVIVHCSAGVGRTGTFIA
| . |    ...  |.. .| | ..||| ||.|||||.|.
DGtvPsdailkkfleitekaeGaiavhCkaGLGrtgtlig
Phosphatase Aque_PTPRB-1.AA Subfamily.DSP19.PD 1053-1096 35 9.1e-06 17.0 In-house 67-105 (139) Show / Hide 
Range on Protein: 1053-1096
Range on HMM: 67-105/139
Sequence Identity: 35% (15 aa)

PALDFVREVHEVAssafGPVIVHCSAGVGRTGTfIALGTLLQHI
||||..|...      | |.|||.||| |. . .... |...  
ealdFieearskd----grvlvHCnAGvSRsas-vviaylmkde
Sequence
Name Sequence Type Origin Length Description Download
Aque_PTPRB-1.AA Protein None 1196 None Fasta, JSON
Aque_PTPRB-1.NA RNA None 3588 None Fasta, JSON
Aque_PTPRB-1.AA.PD_880-1137 Protein Phosphatase Domain None 258 None Fasta, JSON