• Phosphatome.Net

Gene aque_GAK-A

aque_GAK-A
Species: A.queenslandica
Alias: aque_GAK-A
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: Auxilin
Protein domain

Protein domains of aque_GAK-A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase aque_GAK-A.AA GAK 41-310 49 5.4e-144 481.46 In-house 1-277 (277) Show / Hide 
Range on Protein: 41-310
Range on HMM: 1-277/277
Sequence Identity: 49% (139 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYALKRQIVA-SENIKAIKQEITFLTQLSGHPHIINFIGAAS-SKD-PAGGSAEFLIVTELITGGELVDIVN---
. |..||||||..||.||||. || .||||| . .  .  .|| .|| .. .|.||. |. |..|.. |..    . ||.|. .|.  .. |||.     
YRVRCVIAEGGFAFVYVAQDVQTGREYALKRMLSHDMQANRAIINEICMMKKLQGHENIVQFCDASYISREESNQSQAEYLLLMEYCKFSQLVDCLKRME

-TRPLSPRQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGSVKLCDFGSATTQRLTPDHSWSATQRGLTEDEIQANTTPMYRAPEMIDLYS
   |.|.  |||.|| .| |..||||| |||||||||  .||.|.  ..  ||||||||||  . || |||| .| . |||.  .|||||| |||.||||
CYKPFSCDCVLRIFYQMCRAVQHMHSQKPPIIHRDIK--IENFLIGNQKTIKLCDFGSATTKSHYPDYSWSAQKRSMVEDEMFRHTTPMYRSPEMCDLYS

NYPINEKGDIWALGCLLYKLCFQEHPFEDSAKLRILNANYH--IPPGDNVYKEFHNIIRSCLVVDPTKRPSVDSIVAQL
|.||..| ||||.||.|| .|. .|||||.||||| |.||   ||| || |  || .|| || |.|  |...  .| ..
NWPIGHKQDIWAMGCMLYFMCYRQHPFEDGAKLRIINGNYMKPIPPQDNQYMCFHDLIRACLQVNPDERLDIAMVVEYM
Kinase aque_GAK-A.AA NAK 41-310 40 9.40000000001e-128 428.58 In-house 1-299 (299) Show / Hide 
Range on Protein: 41-310
Range on HMM: 1-299/299
Sequence Identity: 40% (123 aa)

LKVKKVIAEGGYGFVFVAQ---------DTSTGIDYALKRQIVAS--ENIKAIKQEITFLTQLSGHPHIINFIG-AASSKDPAGGSAEFLIVTELITGGE
..|.|..||||...|...|         ..|.|  |||||.|. |  . ..|.|.|| .. .|..|..|. .|. .....|   |. | ... |.  .| 
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS

LVDIVNTRP------LSPRQVLRVFYETCQAIAHMHSQTP--PIIHRDIKVGVENLLLTD---KGSVKLCDFGSATTQRLTPDHSWSATQRGLTEDEIQA
|.|. |.|       .. ...|. |...|.....||.. |  ||||||||  .||.|| .   .|  |||||||.||....|. .|.| .| . .|.|. 
LWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIK--IENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINK

NTTPMYRAPEMIDLYSNYPINEKGDIWALGCLLYKLCFQEHPFED------SAKLRILNANYH--IPPGDNVYKEFHNIIRSCLVVDPTKRPSVDSIVAQ
.||||||||||.||||| ||.|| |||||||.|||.|| .|||||      |.||.|.|.||   ||. .. ....|..|| .|..|| .||... .. |
YTTPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHPFEDCYQRHDSSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQ

L
|
L
Kinase aque_GAK-A.AA NAK-Unclassified 41-312 24 5.9e-81 275.26 In-house 1-405 (405) Show / Hide 
Range on Protein: 41-312
Range on HMM: 1-405/405
Sequence Identity: 24% (102 aa)

LKVKKVIAEGGYGFVFVAQ--------D------TSTGIDYALKRQIVASEN-IKAIKQEITFLTQLSGHPHIINFIGAASSKDPAG-GSAEFLIVTELI
 .. . .|||| .||....        |       |..  |.||| |. .|. ... | ||     . .||.|.  |.   ..   . .| | ... |. 
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQSYEVFMLMEYC

TGGELVDIVN------TRP-----LSPRQVLRVFYETCQAIAHMHSQTP--------------------------------------------PIIHRDI
 .| |.|. |      .|      .. . .|. .. .||.|. ||.. |                                            |.|||||
SRGSLQDFMNNQRTIYQRLTEQTRFHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHRDI

KVGVENLLLT---------------------------------------------------------DKG-SVKLCDFGSATTQRLTPDHSWSATQRGLT
|  .|| |.                                                          ...   |||||||... . |.     .....  
K--IENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIE---NRQEMQYL

EDEIQANTTPMYRAPEMIDLYSNYPINEKGDIWALGCLLYKLCFQEHPFEDSAKLR-------ILN--ANYHIPPGDNVYKEFHNIIRSCLVVDPTKRPS
.|.|  .||| ||||||||||.. ||.|| |||||||.|||.||   |||..  |        ||.  ..| .|.  |    .|| |. .|..||. ||.
QDWINMHTTPQYRAPEMIDLYRCCPIDEKIDIWALGCFLYKMCFYTTPFEMCGQLHNASVTYKILHGLGKYEFPSNHNYSNQLHNLIKIMLNEDPIQRPN

VDSIVAQLYP
.  .  ..  
IYQVLNHICQ
Kinase aque_GAK-A.AA BIKE 41-303 38 8.1e-75 254.87 In-house 1-261 (267) Show / Hide 
Range on Protein: 41-303
Range on HMM: 1-261/267
Sequence Identity: 38% (106 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYALKRQIVASE-NIKAIKQEITFLTQLSGHPHIINFIGAASSKDPAGGSAEFLIVTELITGGELVDIVNTRPLS
  | ...||||.  ||... .. |. .||||. |  | .... . |.... |.|||  |. .. ..      .|  | .| .|   . ..|.. | |   
VTVEEQLAEGGFAMVFLVR-DHKGNKCALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIG-NGVWECMILMEYCRH-QVVNMMNQRLQQ

P-----RQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKG--SVKLCDFGSATTQRLTPDHSWSATQRGLT--EDEIQANTTPMYRAPEMID
        ||..| ..| |.. .|    |||||| |  ||| ||.|.|     ||||||||.. | |       . | .  .|||. .||  ||||||||
GQYFTEQEVLQIFCDVCEAVSRLHHCQTPIIHRDLK--VENILLHDHGPPHYVLCDFGSATNKFLNPQ------KHGVNYVKDEIEKYTTMCYRAPEMID

LYSNYPINEKGDIWALGCLLYKLCFQEHPFEDSAKLRILNANYHIPPGDNVYKEFHNIIRSCLVVDPTKRPSV
|||  .|  | |||||||.||||||   ||. | .| | . |. ||   .  .| |  ||  | .|. |||..
LYSGKEITTKADIWALGCMLYKLCFFCLPFGES-QLAICDGNFTIPDNSKYSREMHCLIRYMLEPDMEKRPDI
Kinase aque_GAK-A.AA S_TKc 41-311 23 1.3e-55 192.01 SMART 1-231 (231) Show / Hide 
Range on Protein: 41-311
Range on HMM: 1-231/231
Sequence Identity: 23% (68 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYALKRQIVASENIKAIKQEITFLTQLSGHPHIINFIGAASSKDPAGGSAEFLIVTELITG--GELVDIVNTRP-
 .. ..| .|..| |. .....||  .|.|.        . |..||  | .  .||.|......  .        .. .|.|.. |  |.| |.   |. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGR

------LSPRQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGSVKLCDFGSATTQRLTPDHSWSATQRGLTEDEIQANTTPMYRAPEMIDL
      ... .. ...|..|.|....||.   |||||.|   ||.||..   .|.||||.|.                          || |.|||..  
HGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLK--PENILLDE--HIKICDFGLARQL-------------------TTFCGTPWYMAPEVL--

YSNYPINE-KGDIWALGCLLYKLCFQEHPFEDSAKLRILNANYHIPPGDNVYKEFHNIIRSCLVVDPTKRPSVDSIVA--------QLY
    . .  | |.|..||.|| ..  . ||.     ....            .|. ..|| ||..||.|||..  . .        .  
----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase aque_GAK-A.AA Pkinase 41-310 21 6e-48 170.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 41-310
Range on HMM: 1-293/293
Sequence Identity: 21% (68 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYALKRQIVASENIKAIKQ-----EITFLTQLSGHPHIINFIGAASSKDPAGGSAEFLIVTELITGG----ELVD
......| .|..| |. ... .||. .|.|.  . .|. .  ..     ||  .  | .||.|. ....  .      . .  .|.|.  ||    .| |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFD

IVN---TRPL--SPRQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGSV----KLCDFGSATTQRLTPDHSWSATQRGLTEDEIQANTTPM
..     ...  |.... ...|.........||.   |||||.|   ||.|. ..| .    |.||||.|   .         . ..   . .    || 
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLK--PENILIDNNGHIDACVKICDFGLAKQFD---------Y-NNS-MTTFCG--TPW

YRAPEMIDLYSNYPINEKGDIWALGCLLYKLCFQEHPFEDS------AKLRILNANYH------IPPGDNVY-----------------KEFHNIIRSCL
|.||| |   .. ..  | |.|..||.|| ... . || ..       .. ... . .      .|  ....                 .|.  .|..||
YMAPEVIR--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

VVDPTKRPSVDSIVAQ--L
 .||.|||. . |.    .
CKDPKKRPTAEQILQHPWF
Phosphatase aque_GAK-A.AA CAMK 46-306 17 5.5e-45 142.45 In-house 1-419 (425) Show / Hide 
Range on Protein: 46-306
Range on HMM: 1-419/425
Sequence Identity: 17% (73 aa)

VIAEGGYGFVFVAQDTSTG------------IDYALKR----QIV-------------------------ASENIKAIKQEITFLTQLSG------HPHI
.. .|..| |. .....|.              .| |     ..                            .. | ...||  . .|.|      ||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INFIGAASSKD---------PAGG-----SAEFLIVT---ELITGGEL----VDIVNTR----------------PLSPRQVLRVFYETCQAIAHMHSQT
|... .  ...                    .. .|.   |...||||     | .  .                 .. |.. |.|   |.|....||. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

PPIIHRDIKVGVENLLLTDK-----------------GSVKLCDFGSATTQRLTPDHSWSATQRGLTEDEIQ-------------ANTTPMYRA-PEMID
  |.|||.|   ||.||.|.                 . .|..||| |.  .   .    . . | .    .                || | | ||.. 
--IVHRDLK--PENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLN

LYS-----------NYPINEKGDIWALGCLLYKLCFQEHPFEDS-----------------AKLRILNANYHIPPGD----------------------N
  .           . ....| |.|..|..|| .   . ||...                  . .|....|. ||                        .
GKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHF

VYKEFHNIIRSCLVVDPTKRPSVDSI
| .|  . ||..|.|||.||.... .
VSQECKDLIRKMLQVDPEKRMTIEQC
Kinase aque_GAK-A.AA TKL-ciliate1 98-310 26 5e-42 141.62 In-house 55-279 (279) Show / Hide 
Range on Protein: 98-310
Range on HMM: 55-279/279
Sequence Identity: 26% (62 aa)

IINFIGAASSKDPAGGSAEFLIVTELITGGELVDIVNTRPL-----SPRQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGSVKLCDFGSA
| ..|.  . .. . .   | |..|.  .| ..||    .      .  . .|. ..  | . ..|.  .|.||||.|  ..|.|.      | |.|.. 
IKQHINLQQLQGISFYDNNFYIIMEHCHKGTMFDICHRKHSQIYMIKWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLK--MQNILYDEPYQYKICNFPHV

TT--QRLTPDHSWSATQRGLTEDEIQANTTPMYRAPEMID--LYSNYPINEKGDIWALGCLLYKLCFQEHPFEDSAKLRILNANYHIPPGD---------
..    ..   |  . |      |.|.|||....||| .|  ...||||||| ||.|.| ..| ||| . ||.   |.  .|    .. .          
KIADFHRIRNCSFQDMQ-----NEMQRNTTFHWMAPEQMDPHIFPNYPINEKIDIYAYGIVMYILCFRKTPFQQ--KMSVINIMCYWCEFPGRPNLGPQF

---NVYKEFHNIIRSCLVVDPTKRPSVDSIVAQL
       .|||..  |.  .| |||. . |   |
IHFDCPQNFHNLMMRCWCQNPNKRPNFNEIIQIL
Kinase aque_GAK-A.AA Ciliate-E2 41-302 18 5.3e-42 141.96 In-house 1-354 (365) Show / Hide 
Range on Protein: 41-302
Range on HMM: 1-354/365
Sequence Identity: 18% (73 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYA----------------LKRQIVASENI-----KAIKQEITFLT---------------QLSGHPHIINFIGA
 |. |.| .|..| |. ... ... ..|                 | .|.| ...     ..|||||  .                ..  ||.||... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

AS--SKDPAGGSAEFLIVTELITGGELVDIVNTRPLSP------------RQVLRVFYETCQ---------------AIAHMHSQTPPIIHRDIKVGVEN
    ...       . .|.|.. ||.| |. . ....             ......... .|               |. ..||. . |||||||   ||
FQEKDDN------NIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIK--PEN

LLLTDKGSVKLCDFGSATT-------------------------------QRLTPDHSWSATQRGLTEDEIQANT------TPMYRAPEMIDLYS-----
.|.     .|..||| ..                                |                   || |.      ||.| |||..   .     
ILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQ------------------IIQQNMFNTICGTPGYMAPEILNGKKYDNQQ

-NYPINEKGDIWALGCLLYKLCFQEHPFEDSAKLRILNANYHIP----------------PGDNVYKEFHNIIRS----CLVVDPTKRPS
   . ..| |||.||..|| ..| ..||       |.. .. .|                  ... .|  ..|.     .|..|| ||..
KQKGYDYKCDIWSLGVILYEMLFGKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT
Kinase aque_GAK-A.AA TKL 47-310 18 7.8e-42 145.3 In-house 1-364 (364) Show / Hide 
Range on Protein: 47-310
Range on HMM: 1-364/364
Sequence Identity: 18% (68 aa)

IAEGGYGFVFVAQDTS--------TGIDYALKRQIV-------------------------ASENIKAIKQEITFLTQLSG--HPHIINFIGAASSKDPA
| .||.| |. ..           || | | |.  .                         . |. .. ..|.  . ..|   ||.|. |.|.. . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------GGSAEFLIVTELITGGELVDIVNTRPLSPRQVLRVFYETCQAIAHMHSQT------PPIIHRDIKVGVENLLLTDKGS--------------V
       |.. .. ||.|.. || | ....     . | .|  ..........||..      |||||||.|   .|.|. ...               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLK--SKNILVDENWTNVSNYMYNPNADWCC

KLCDFGSAT-TQRLTPDHSWSATQR------GLTEDEIQANTTPMYRAPEMID---LYSNY----------PINEKGDIWALGCLLYKLCFQEHPFEDSA
|.|||| ..  .. . .  .. |..         .  .    || . |||...    |...          . .|| |... | .|. ..  ..|..|  
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

K-------------LRILNANYHIPPG------------DNVYKEFHNIIRSCLVVDPTKRPSVDSIVAQL
                . . ... |.             ... ... ...  |   ||.|||| . |. .|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase aque_GAK-A.AA STE 41-304 20 2.2e-35 122.43 In-house 1-349 (359) Show / Hide 
Range on Protein: 41-304
Range on HMM: 1-349/359
Sequence Identity: 20% (75 aa)

LKVKKVIAEGGYGFVFVAQDTS---------------TGIDYALKRQIVAS------------------ENIKAIKQEITFLTQLSG-HPHIINFIGAAS
..  ..| .|..| |. | .                 ||  .| |.  . .                  |... |..|| .. ...  ||.|....|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SKDP-AGGSAEFLIVTELITGGELVDIVNT-----RPLS----------PRQVLRVFYETCQA-IAHMHSQTPPIIHRDIKVGVENLLLTDKGSVKLCDF
 ...  .   |  |. |.. || | ||...     .||.            |. .. ......  .. ||.   |||||||    | ||     ||||||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIK--PANILL-----VKLCDF

GSATTQRLTPDHSWSATQRGLTEDEIQA---------NT-----TPMYRAPEMIDLYSNY---PINEKGDIWALGCLLYKLCFQEHPF---EDS-AKLRI
| ..    . ... . .        .           ..     || . |||.|.  ..    . ..| ||| |||..  ..  ..|.    .  | ..|
GVCGQLTDSMANI-Q-S-------NN-IIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMI

LNAN-------------YHIP--PGD------------------NVYKEFHNIIRSCLVVDPTKRPSVD
.. .              ..|  | .                  .. .||.. |. ||. || |||...
PFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTAS
Kinase aque_GAK-A.AA Ciliate-E2-Unclassified 42-306 20 5e-35 118.94 In-house 2-346 (352) Show / Hide 
Range on Protein: 42-306
Range on HMM: 2-346/352
Sequence Identity: 20% (74 aa)

KVKKVIAEGGYGFVFVAQDTSTGIDY-----ALKRQIVASENIKA---IKQEITFLTQL------------------SGHPHIINFIGAASSKDPAGGSA
|. |.| .||.| |. .|. ...  |     . | ||... .|.    |..|.. . ..                  . ||.|.... .  .|.      
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ------

EFLIVTELITGGELVDIVNT------------------RPLSPRQVL-----RVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKG---SVKLCDF
 . ||.|.. ||.| .. .                   . .. .|..     . |.. .|.. ..|..   |||||||   ||.|....|    .|..||
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIK--PENILFDNNGKNYYIKIIDF

GSAT---------TQRLTPDHSWSATQRGLTEDEIQANT--TPMYR----APEMIDLYSNYPIN-EKGDIWALGCLLYKLCFQEHPFED-----------
|..          |. .        .... . ....  .  ||.|     |||...   ..    .| |||.||..|| ..|...||.|           
GISKKYQQNNNCDTNQQ--------QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLIT

---------SAKLRILNANYHIPPGDN---------VYKEFHN-IIRSCLVVDPTKRPSVDSI
           .  |.. |. .|. ..          .|.| | .....|...| ||.. . |
QWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI
Phosphatase aque_GAK-A.AA Subfamily.PTEN.PD 401-564 29 1.1e-28 90.3 In-house 1-165 (305) Show / Hide 
Range on Protein: 401-564
Range on HMM: 1-165/305
Sequence Identity: 29% (49 aa)

DITYVTSRILVMSYPFEE-GGVGRPNVLKEVSAYLEGTHPSQY-LVFNLsGEQYDTDQLSGQVVDYEWPNRAMPPLESLVELCRQLDSWLRADFKNVLVI
||.|. . ..|.||| |   .. . |.| ..  .|   .  .   ..|   ..... ...|.|  |       |.|| | |.....|.|| .| .|| ..
disyilvnlivlsypvetyekllyrnslddlillltvykgkgklrilna-rgekedsdfdgrvavypfdDhnpptleLleeivedvdkwLkedksnVvav

HCKDGVHPSGILVVSYLLFLRALPSPSSALRLFTARRLPEGQGMDIsPSDRRYLNYMMAL-SRPAPY
||| |   .|.....|||.    .|.. ||....  |  ...|  | || |||..|   |     ||
HCkaGkGRtGvmicayLlksgikksadealaiydekRtkdkkGVti-PSQrRYvqYfsklvkssvpy
Kinase aque_GAK-A.AA TyrKc 41-310 20 1.8e-13 -4.95 SMART 1-280 (280) Show / Hide 
Range on Protein: 41-310
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

LKVKKVIAEGGYGFVFVAQDTSTGIDYALKRQIVASENIKAIKQEITFLTQL-SGHPHIINFIGAASSK-------DPAGGSAEFLIVTELITGGELVDI
.. .|.. || .| |. .. .   |. | |     .  .... .|.  ...|   ||.|....|.....       .|       .||.|.  .| | | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP------LMIVMEYMPHGDLKDY

V-NTRP-LSPRQVLRVFYETCQAIAHMHSQTPPIIHRDIKVGVENLLLTDKGSVKLCDFGSATTQRLTPDH-SWSATQRGLTEDEIQANTTPMYR-----
  ..|| |.... |   .  ..  .. ||.  ..||||.     | |..... || .||| .   |   |. ..        .| . . ..   .     
LRKHRPKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLA--ARNCLVGENHTVKISDFGLS---RDIYDDDQQG-----ESKDYYRKKEHKGGKTMLPI

---APEMIDLYSNYPINEKGDIWALGCLLY---KLCFQEHP------FEDSAKLRILNANYHIPPGDN--------VYKEFHNIIRSCLVVDPTKRPSVD
   ||| |  |. .  ..| |.|. | ...    .. | .|       ...  .. . . |  |. .|          .| ..|...|   || .||.  
RWMAPECI-NYGKF--TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

SIVAQL
 |. ..
EIHECF
Kinase aque_GAK-A.AA Pkinase_Tyr 41-169 22 2.7e-11 38.86 Pfam 1-137 (270) Show / Hide 
Range on Protein: 41-169
Range on HMM: 1-137/270
Sequence Identity: 22% (32 aa)

LKVKKVIAEGGYGFVFVAQDT----STGIDYALKRQ--IVASEN--IKAIKQEITFLTQLSGHPHIINFIGAAS-SKDPAGGSAEFLIVTELITGGELVD
..  |.. || .| |. .  .    .|.|. | |       .|.  ...  .|.  ..||  ||.|....|. .  ..|     . .||.|.  .| | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN----QIYIVMEYMPHGDLLD

IVNTR-----PLSPRQVLRVFYETCQAIAHMHSQTPPIIHRDI
   ..     ||.. . |   .. ... .. .|.   .||||.
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDL
Phosphatase aque_GAK-A.AA Subfamily.Tensin.PD 458-709 30 1.2e-33 106.3 In-house 2-236 (237) Show / Hide 
Range on Protein: 458-709
Range on HMM: 2-236/237
Sequence Identity: 30% (77 aa)

SGQVVDYEWPNRAMPPLESLVELCRQLDSWLRADFKNVLVIHCKDGVHPSGILVVSYLLFLRALPSPSSALRLFTARRLPEGQGM-DISPSDRRYLNYMM
.|.|. ||.   |||| |  .|..|.||| || .||.|.||| |    |. . .|. . .   |...||  |. .|. . . .  . || |||..|. .|
nekvldlGWPdllaPpleklcsickalesWlkadpqnvvvlhckGgkGrigvvisaymhyskisasadaaldrfalkrfyddkvsgvtqPsqrryveyfs

ALSRPApYKPHPHSFKLTGLNLTSVPIYnEARNGCKPFVEVFVDGERVHTSCnkenMDKLKEYTTKDGQISIPLNTTVYGNLLIIVHHIKSVPlTKRAem
   .  |   . . |    | ..| . ... ||.||. ..   . |.||     . ..    |.   |.|     . |..|.  .| |    |.|     
gllsgs-iklnssplflhyvilhgipnf-dskggcrpflkiyqalqlvytsg----vynvagedterlcitiepalllkgdvlvkcyhkklrs-ttrd--

gmsavKMFKFQIHTGFLstKMTSLTLEKNELDGSavKKTDRFPSSFKVLLNFS
    .|. |.||| .  | ..|..||..|| .   | .|||.  || | ||  
-----vvfrvqfhtgai--kdlklvfekedldea--lkderfpeyakvelvfs
Phosphatase aque_GAK-A.AA PTEN_C2 566-710 25 4.6e-18 66.82 Pfam 1-141 (141) Show / Hide 
Range on Protein: 566-710
Range on HMM: 1-141/141
Sequence Identity: 25% (39 aa)

PHPHSFKLTGLNL-TSVPIYNEARNGC-KPFVEVFVDGERVHTSCNKENMDKLKEY-TTKDGQISIPLNTTVYGNLLIIVHHIK-SV--PLTKRAEMGMS
|.|   .|... .  ..|.  ....|| .|.....   . |   .. .   ..|.| ..|.. . .| . .|.|  .| ..|.. |    ...       
PPPKPLFLHCIIMDHGIPNF-KQGGGCWRPYIQIYQNDQKVF--YTCKKYWHCKKYKQQKCCIFKFPQPCPVQGDVKIQCYHKGPSDLPWMYEEC-----

AVKMFKFQIHTGFLSTKMTSLTLEKNELDGSAVKKT--DRFPSSFKVLLNFSV
   || |...|.|...  . ||. |||||. | | .  .|||. ||| . || 
---MFRFWFNTCFIEHNNNRLTFPKNELDK-AWKDKKWKRFPPDFKVEVVFSE
Phosphatase aque_GAK-A.AA Subfamily.TPIP.PD 469-706 24 5e-18 55.4 In-house 13-241 (245) Show / Hide 
Range on Protein: 469-706
Range on HMM: 13-241/245
Sequence Identity: 24% (58 aa)

RAMPPLESLVELCRQLDSWLRADFKNVLVIHCKDGVHPSGILVVSYLLFLRALPSPSSALRLFTARRLPEGQGMDI----SPSDRRYLNYMMALSRPAPY
.| || || ...... || .| .||..|||| |    | .| ..|.   ..     .|  |. ||  . ..        || .||..|.. .   ..  |
hnvPtleelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliaseifltaeesldyfgerrtdkthsnkfqGvetPsqnryvgylaqvkhlynw

KPHPHSFkltgLNLTSVPIYNEARNGCKPFVEVFVDGERVHTSCNKENMDKLKEYTTKDGQISIPLNTTVYGNLLIivHHIkSVPLTKRAEmgmsAVkMF
.      | .  . ||.   . |   |.| .. . | .|..  |   |..  |    |..     .| .. .  . . || |  .     .  | | . |
nlpprri----lfikrfiiysirgdvcdlkvqvvmekkvvfsstslgncsilhdietdkilinvydgpplyddvkv--qff-ssnlpkyyd----nc-pf

KFQIHTGFLSTKmtSLTLEKNELDGSAVKKTD-RFPSSFKVLL
 |.  .   |.| .||||    .|.   .|  | | .      
ffwfntsfiqnn--rlclprneldnphkqkawkiyppefavei
Phosphatase aque_GAK-A.AA Family.DSP.PD 406-699 16 6.5e-15 45.1 In-house 140-368 (387) Show / Hide 
Range on Protein: 406-699
Range on HMM: 140-368/387
Sequence Identity: 16% (49 aa)

TsrilvmsypfeeggvgrpnvlkevsaylegthpsqylvfnlsgeqYDTD----QLSGQVVDYEWPNRAMPPLESLveLCRQLDsWLRA--DFKNVLVIH
|                                             .| .    .|. ..... ..    ||||.|  ... .| ..    | |.|..||
t---------------------------------------------ddkpqftkelgikylripidDhnapplenl--fekaid-fieegndskgvVlVH

CKDGVHPSGILVVSYLLFLRALPSPsSALRLFTARRlpegQgMDISPSDRrYLNYMMALSRPApYKPHPHSFKLTGLNLTSVPIYNeARNGCKPFVEVFV
| |.  || |.. ||.. . |  .  ||...  .|    .   | |... .| ....|. .   |.. . . |       |.      ......  . . 
CkaGkgRsgtliiaYlmksegltle-ealdwvrskR----p-gvitpnqg-flkqlkdlekek-lkvssevmelrfvissivqnlg-svevsvsvlkkva

DGERVHTSCnkenmDKLKEYTTKDGQISIPLNTTVYGNLLiivhhiksVPLTKRAEMGMSAVKMFKFQIHTGFLstKMTSLTLEKNELDGSAVKKTD-RF
 . . ...       |.   ..   | |     ..|  .        | |.|.    .    ..... .|..   |  || |.|.|||    .| .  ..
tekakldrl-----kiLvideqekvvitikdglplsgDVk--------velfkknldkiirdiilntfFvtnyi--kdeslvlvkkeldelhkskifdvy

P
 
k
Sequence
Name Sequence Type Origin Length Description Download
aque_GAK-A.AA Protein None 1285 None Fasta, JSON
aque_GAK-A.NA RNA None 3855 None Fasta, JSON