Gene aque_DUSP11
aque_DUSP11
Species: A.queenslandica
Alias: aque_DUSP11
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of aque_DUSP11.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | aque_DUSP11.AA | Subfamily.DSP11.PD | 54-190 | 56 | 2e-64 | 206.7 | In-house | 2-140 (141) | Show / Hide |
Range on Protein: 54-190 Range on HMM: 2-140/141 Sequence Identity: 56% (78 aa) VEKEFTSTQLVRMLQSKNLNLGLVIDLTNTDRYYSWKSFEDLGIEHYKLRCPGHEIPSEEIYKSFSERLSRFL--SKESNEYVAVHCTHGVNRTGYLICR .|..|....|...||.|| .||||||||||||||..|...| |....||.|||||.|..|..|.|.|....|| .|.......|||||||||||||||| eeerfapedlleklqeknkklGLvidltntdryykkkeltdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCr YLVEHCGFETEDAIKKFGDARGHSMERENYLKDLRKLVN ||....|...||||..| .|||||.||||||.||.||.. ylidvegyspedaieafeearGhslerenyledLkklak |
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| Phosphatase | aque_DUSP11.AA | Subfamily.RNGTT.PD | 55-188 | 43 | 2.1e-38 | 122.3 | In-house | 2-136 (140) | Show / Hide |
Range on Protein: 55-188 Range on HMM: 2-136/140 Sequence Identity: 43% (59 aa) EKEFTSTQLVRMLQSKNLNLGLVIDLTNTDRYYSWKSFEDLGIEHYKLRCPGH-EIPSEEIYKSFSERLSRFLSKESNEYVAVHCTHGVNRTGYLICRYL |..|....|. |.... .||||||||||.||| . .|. |... ||.| |. | |..| |.| . ..||.|. .| ..|||||| ||||.||. || eeafepemlksylktlkvklglvidltntsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayL VEHCGFETEDAIKKFGDARGHSMERENYLKDLRKL ||. .. |.|.. | || . .|.|||.| |. vekedwsveaavalfakarppGiykedylkelfkr |
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| Phosphatase | aque_DUSP11.AA | Family.DSP.PD | 69-199 | 27 | 3.1e-25 | 80.4 | In-house | 128-254 (387) | Show / Hide |
Range on Protein: 69-199 Range on HMM: 128-254/387 Sequence Identity: 27% (36 aa) SKNLNLGLVIDLTNTDRYYSWksfeDLGIEHYKLRCPGHEIPSEEIYksFSERLSrFLSK--ESNEYVAVHCTHGVNRTGYLICRYLVEHCGFETEDAIK |.|. ...|| ... .|||..... .. |. |. |.. | . . |... .|.. |.|||..|..|.| ||. ||... |.. |.|.. lkelgvtkivnltddkpqftk----elgikylripidDhnapplenl--fekaid-fieegndskgvVlVHCkaGkgRsgtliiaYlmksegltleeald KFGDAR-GHSMERENYLKDLRKLVNEGDKSNNET . ..| |. ....|| | .| .| | ..|. wvrskRpgvitpnqgflkqlkdlekeklkvssev |
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| Phosphatase | aque_DUSP11.AA | Subfamily.CDC14.PD | 70-165 | 31 | 1.1e-14 | 45.8 | In-house | 144-232 (258) | Show / Hide |
Range on Protein: 70-165 Range on HMM: 144-232/258 Sequence Identity: 31% (30 aa) KNLNLGLVIDLTNTdrYYSWKSFEDLGIEHYKLRCPGHEIPSEEIYKSFSERLSRFlskesNEYVAVHCTHGVNRTGYLICRYLVEHCGFETEDAI ...|. .. | . | |.|.| |..|. | .||..| |.| | . . . .|||| |. |||.|| ||. | .|....| rknnvttivrLnkk--lYdakkftdaGfahlDlffiDGtvPsdailkkfleiteka-----eGaiavhCkaGLGrtgtligcylikhyrftaaeti |
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| Phosphatase | aque_DUSP11.AA | Subfamily.PTEN.PD | 105-174 | 28 | 6.7e-14 | 43.0 | In-house | 68-138 (305) | Show / Hide |
Range on Protein: 105-174 Range on HMM: 68-138/305 Sequence Identity: 28% (20 aa) PGHEIPSEEIYKSFSERLSRFLSKESNEYVAVHCTHGVNRTGYLICRYLVEHCGFETE-DAIKKFGDARGH | |. |. ... | ....|...... ||||| | ||| .|| ||.... .... .|.. ....| . dDhnpptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadealaiydekRtk |
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| Phosphatase | aque_DUSP11.AA | Subfamily.DSP23.PD | 77-184 | 29 | 2.1e-11 | 35.1 | In-house | 17-122 (128) | Show / Hide |
Range on Protein: 77-184 Range on HMM: 17-122/128 Sequence Identity: 29% (31 aa) VIDLTNTDRYYSwKSFEDLGIEHYklRCPGHEIPSEEIYKSFSERLSRflSKESNEYVAVHCTHGVNRTGYLICRYLVEHCGFETEDAIKKFGDARGHSM ...||. . || .. ..|... . | . |. | . . . . .....| |.||| |. ||| |. |||.. |. ..|||| |.| | lvslttegapys-eaapsltlrri--dipdfcPPaleqvarlvrivee--aekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsi ER---ENYLKD . .|| etveqekavkd |
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| Phosphatase | aque_DUSP11.AA | Subfamily.TPIP.PD | 106-179 | 29 | 1.4e-10 | 32.3 | In-house | 12-86 (245) | Show / Hide |
Range on Protein: 106-179 Range on HMM: 12-86/245 Sequence Identity: 29% (22 aa) GHEIPSEEIYKSFSERLSRFLSKESNEYVAVHCTHGVNRTGYLICRYLVEHCGFET-EDAIKKFGDARGHSMERE |..| | .|.. . .|.|. .. ||.|| | .||| ..| .|.. |.| |.... ||. | . . dhnvPtleelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliaseifltaeesldyfgerrtdkthsn |
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| Phosphatase | aque_DUSP11.AA | Subfamily.PRL.PD | 83-179 | 26 | 1.9e-10 | 31.8 | In-house | 33-128 (140) | Show / Hide |
Range on Protein: 83-179 Range on HMM: 33-128/140 Sequence Identity: 26% (25 aa) TDRYYSWKSFEDLGIEHYKLRCPGHEIPSEEIYKSFSERLSRFLSKESNEYVAVHCTHGVNRTGYLICRYLVEHcGFETEDAIKKFGDARGHSMERE . |. . ... ||| | |..|. ... | | . ..|... ||||| |. |. |.. |.|. |...|||.. . | ..... cepsydaeklkeegievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalaliea-Gmkyedavefirekrrgainsk |
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| Phosphatase | aque_DUSP11.AA | Subfamily.PTPDC1.PD | 130-183 | 35 | 3.4e-10 | 30.8 | In-house | 165-218 (229) | Show / Hide |
Range on Protein: 130-183 Range on HMM: 165-218/229 Sequence Identity: 35% (19 aa) SNEYVAVHCTHGVNRTGYLICRYLVEHCGFETEDAIKKFGDARGHSMERENYLK .. .|||| | ||| ||. ||| . ...|.|||. . | .|. . .. eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqve |
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| Phosphatase | aque_DUSP11.AA | DSPc | 68-191 | 14 | 4.1e-10 | 37.08 | Pfam | 15-151 (151) | Show / Hide |
Range on Protein: 68-191 Range on HMM: 15-151/151 Sequence Identity: 14% (22 aa) QSKNLNLGLVIDLT-----NTDRYYSWKSFEDLGIEHYKLRCP-GHE---------IPSEEIYKSFSERLSRFLSK--ESNEYVAVHCTHGVNRTGYLIC . .... .||..| | ... . . .....| |. ... |.. | .... |... .... | |||..|..|...|.. FLQKHGITHVINCTMECPNN---------WFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYF-PMATDFIDDCRQKGGKVLVHCQAGISRSACLCI RYLVEHCGFETEDAIKKF-----GDAR-GHSMERENYLKDLRKLVNE .|| .. ..|. . . | .. ... |... |. . . AYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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| Phosphatase | aque_DUSP11.AA | Subfamily.DSP12.PD | 110-186 | 26 | 4.1e-08 | 24.5 | In-house | 59-136 (143) | Show / Hide |
Range on Protein: 110-186 Range on HMM: 59-136/143 Sequence Identity: 26% (21 aa) PSEEIYKSFSErLSRFLSK--ESNEYVAVHCTHGVNRTGYLICRYLVEHCGFETEDAIKKFGDARGHSMERENYLKDLR |.|.. . . | ||... | .. | |||. || | .. ||. . ... |.|.|. ... . |..|. |. peedlLshlde-avrFieeglekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekkkeiepNegFleQLk |
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| Phosphatase | aque_DUSP11.AA | Subfamily.PTPMT1.PD | 88-186 | 27 | 2.5e-07 | 21.7 | In-house | 44-141 (146) | Show / Hide |
Range on Protein: 88-186 Range on HMM: 44-141/146 Sequence Identity: 27% (27 aa) SWKSFEDLGIEHYKLRCPGH-EIPSEEIYKSFSERLSRFLSKESNeyVAVHCTHGVNRTGYLICRYLVEHCGFETEDAIKKFGDARGHSMERENYLKDLR | . ...||.|...| . |.|| | . | .... ||.|. | ||| | | . |. ||... . .|.|.| . . | .... .. |. steewkklGveqlqlatvDfteapslekleegvefiekvaskgss--vYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqirlkskqwralq |
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| Phosphatase | aque_DUSP11.AA | Subfamily.DSP10.PD | 71-172 | 25 | 4.6e-07 | 20.9 | In-house | 25-122 (141) | Show / Hide |
Range on Protein: 71-172
Range on HMM: 25-122/141
Sequence Identity: 25% (25 aa)
NLNLGLVIDLTNTdryySWKSFEDLGIEHYKlRCPGHEIPSEEIYKSFSERLSrFL--SKESNEYVAVHCTHGVNRTGYLICRYLVEHCGFETEDAIKKF
|.. |...|.. . . ||. |. .|| | | .. . ... . |.| | |. .. .. | |||. |. |. .. |...| ...| | ..|
rlgikyvlnvtts----vPnffeekglvryk-ripvsdsgkqnlkqkfeeale-fieearkrgsrvlvhchaGisrsatvviayvmkhlslslseaykfv
GDAR
kekr
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| Phosphatase | aque_DUSP11.AA | Family.OCA.PD | 70-149 | 25 | 5.6e-07 | 20.5 | In-house | 29-110 (165) | Show / Hide |
Range on Protein: 70-149 Range on HMM: 29-110/165 Sequence Identity: 25% (21 aa) KNLNLGLVIDLTNTD-RYYSW-KSFEDLGIEHYKLRCPGHEIPSEEIYKSFSERLSRFLSKESNEYVAVHCTHGVNRTGYLI |.|.| .| |.. . | | .|. |. . ... ... . .|| . |. ..| .. | | .||..|..||| .. ktLkLktiislspeelpqesllkfveeeniklihikvdkkkkdlveieeellkrvlkilldvdnypvlihcnkGkhrtglvv |
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| Phosphatase | aque_DUSP11.AA | Subfamily.OCA.PD | 70-149 | 25 | 5.6e-07 | 20.5 | In-house | 29-110 (165) | Show / Hide |
Range on Protein: 70-149 Range on HMM: 29-110/165 Sequence Identity: 25% (21 aa) KNLNLGLVIDLTNTD-RYYSW-KSFEDLGIEHYKLRCPGHEIPSEEIYKSFSERLSRFLSKESNEYVAVHCTHGVNRTGYLI |.|.| .| |.. . | | .|. |. . ... ... . .|| . |. ..| .. | | .||..|..||| .. ktLkLktiislspeelpqesllkfveeeniklihikvdkkkkdlveieeellkrvlkilldvdnypvlihcnkGkhrtglvv |
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| Phosphatase | aque_DUSP11.AA | DSPc | 62-191 | 14 | 6.8e-07 | 19.01 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 62-191 Range on HMM: 1-172/172 Sequence Identity: 14% (26 aa) QLVRML-----------Q------SKNLNLGLVIDLT------------NTDRYYSWKSFEDLGIEHYKLRCP-GHE-------IPSEEIYKSFSERLSR . .... . |..| .||..| | |..| . . . . ...| .. ... |.. | ..... GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKN-DMHY-TNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYF-PEVYD FLSK-ESNEY-VAVHCTHGVNRTGYLICRYLVEHCGFETEDAIKKF-----GDAR-GHSMERENYLKDLRKLVNE |... ... . | ||| .|..|...|.. || .. ..||. . ..| .. .. .|... |. . . FIHDCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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| Phosphatase | aque_DUSP11.AA | Subfamily.DSP3.PD | 105-188 | 27 | 1.5e-06 | 19.3 | In-house | 61-145 (148) | Show / Hide |
Range on Protein: 105-188 Range on HMM: 61-145/148 Sequence Identity: 27% (24 aa) PGHEIPSEEIYKSFSErLSRFLSK---ESNEYVAVHCTHGVNRTGYLICRYLVEHCGFETEDAIKKFGDARGHsMERENYLKDLRKL . ...|. .. | |.| . |. . ..| | |||..|. |. |. ||. . .. ..|||. . | . | .|| |..| evsDvpefdlskyfee-aadfidealsqkngkvlvhcvvGisRsatlvlayLmirrkltlkeaiktvrkkrei-lPneGflkqLlel |
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| Phosphatase | aque_DUSP11.AA | Subfamily.R_Sponge_2.PD | 97-184 | 25 | 1.8e-06 | 18.7 | In-house | 158-246 (262) | Show / Hide |
Range on Protein: 97-184 Range on HMM: 158-246/262 Sequence Identity: 25% (22 aa) IEHYK-LRCPGHEIPSEE-IYKSFSERLSRFLSKESNEYVAVHCTHGVNRTGYLICRYLVEHcGFETEDAIKKFGDARGHSMERENYLKD . ... . | || |... . .. .|. | |. |. . |.| .|| ||| |. . | . ...|. | | .. ..|..| vtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfialdsvle-rlkaeeeidvfevlktlrtkriglvqd |
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| Phosphatase | aque_DUSP11.AA | Subfamily.DSP19.PD | 110-186 | 25 | 5.3e-06 | 17.5 | In-house | 57-134 (139) | Show / Hide |
Range on Protein: 110-186 Range on HMM: 57-134/139 Sequence Identity: 25% (20 aa) PSEEIYKSFSERlSRFLSKE--SNEYVAVHCTHGVNRTGYLICRYLVEHCGFETEDAIKKFGDARGHSMERENYLKDLR | ... . ..| |. . .. | ||| || |. .. ||... ..|.|..| .|| | ..| |. petkllsylkea-ldFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpcikPneGFikqLk |
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| Phosphatase | aque_DUSP11.AA | Subfamily.N13.PD | 103-162 | 26 | 8.4e-06 | 16.6 | In-house | 164-215 (259) | Show / Hide |
Range on Protein: 103-162 Range on HMM: 164-215/259 Sequence Identity: 26% (14 aa) RCPGHEIPSEEIYK-SFSERLSRFlSKeSNEYVAVHCTHGVNRTGYLICRYLVehcgfetE . | |..||. . | .. .. . .. ..|||. |. |.| ||. . | kwPdhgvPssaaelvqfvaevrll-qt-dagPivvhcsaGiGrsGvlitidvv-------l |
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| Phosphatase | aque_DUSP11.AA | Subfamily.DSP8.PD | 99-177 | 22 | 8.5e-06 | 16.9 | In-house | 48-126 (143) | Show / Hide |
Range on Protein: 99-177 Range on HMM: 48-126/143 Sequence Identity: 22% (18 aa) HYKLRCPGHEIPSEEIYKSFSERLSrFLSK--ESNEYVAVHCTHGVNRTGYLICRYLVEHCGFETEDAIKKFGDARgHSME . ||.| .. .|.. | . |. |. | ..| | ||| | |. .. |.. . .....| . . | .... srflriPvkDkyeekllpwfdkale-fidkarsangkvlvhclaGisrsatvaiayimktlemsldeayrfvkekr-ptis |
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| Phosphatase | aque_DUSP11.AA | PTPc_motif | 98-191 | 13 | 1e-05 | 16.11 | SMART | 1-92 (92) | Show / Hide |
Range on Protein: 98-191 Range on HMM: 1-92/92 Sequence Identity: 13% (14 aa) EHYKLRCPG---H-----EIPSEEIYKSFSERLSRFLSKESNEYVAVHCTHGVNRTGYLICRYLVEHCGFETEDAIKKFGDARGHSMERENYLKDLRKLV ... . ... | .|. . .| ... . ||| .|..||| ... ... .. . .. .|.. . | .... | . . . . TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQ-VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCI NE | LE |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| aque_DUSP11.AA | Protein | None | 375 | None | Fasta, JSON |
| aque_DUSP11.NA | RNA | None | 1125 | None | Fasta, JSON |
| aque_DUSP11.AA.PD_62-191 | Protein Phosphatase Domain | None | 130 | None | Fasta, JSON |