Gene aque_DUSP19
aque_DUSP19
Species: A.queenslandica
Alias: aque_DUSP19
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of aque_DUSP19.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Phosphatase | aque_DUSP19.AA | DSPc | 72-212 | 23 | 4.3e-32 | 113.87 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 72-212 Range on HMM: 1-172/172 Sequence Identity: 23% (41 aa) EIGVALPRLFIASQDVAY--DKSALSVLGVTHILNVAADLPN-----------------AFPSDYVYCSVPMYDD-------EDEVLMQHY-SKCQDFID .. .|.|...|. .. .. |.....||..||.. |. ..|.. |...|| || .... ...| ... |||. GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH EALSKEDGRLLVHCRAGRSRSVSIAVAYMMHKDKSLTVEEALGKI-----RETR-PNADPNAGFFKQLKALEIE .. .. |. ||||.|| |||.....||.|.... .....|. . .. | | ||..|..||...| DC-RQKGGKVLVHCQAGISRSATLCIAYLMKYMN-MSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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| Phosphatase | aque_DUSP19.AA | Subfamily.DSP19.PD | 73-211 | 49 | 5.8e-58 | 185.6 | In-house | 2-138 (139) | Show / Hide |
Range on Protein: 73-211 Range on HMM: 2-138/139 Sequence Identity: 49% (69 aa) IGVALPRLFIASQDVAYDKSALSVLGVTHILNVAADLPNAFPSDYVYCSVPMYDDEDEVLMQHYSKCQDFIDEALSKEdGRLLVHCRAGRSRSVSIAVAY .... |||...|||||.||..|. |..|||||||...||.||.|. |.|....|.... |........|||.||.||. ||.||||.||.|||.|...|| vaevkprlylgsqdvaadkeilkklkitHilnvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskd-grvlvHCnAGvSRsasvviay MMHkDKSLTVEEALGKIRETRPNADPNAGFFKQLKALEI .|. |..|..|.|| |.||.||...||.||.||||..|. lmk-deelslekalekvrearpcikPneGFikqLkeyea |
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| Phosphatase | aque_DUSP19.AA | Subfamily.DSP3.PD | 77-210 | 35 | 5.8e-35 | 111.2 | In-house | 6-146 (148) | Show / Hide |
Range on Protein: 77-210 Range on HMM: 6-146/148 Sequence Identity: 35% (51 aa) LPRLFIASQDVAYDKSALSVLGVTHILNVAAD--------LPNAFPS-DYVYCSVPMYDDEDEVLMQHYSKCQDFIDEALSKEDGRLLVHCRAGRSRSVS |..... ..|| ||. | ||.||.|| | . .... . . |. |.. | . | ..... ||||||||...|..||||..| ||| . ypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsat IAVAYMMHKdKSLTVEEALGKIRETRpNADPNAGFFKQLKALE ..||.| . ..||..||. ..|. | . || ||.||| .|. lvlayLmir-rkltlkeaiktvrkkr-eilPneGflkqLleld |
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| Phosphatase | aque_DUSP19.AA | Subfamily.DSP1.PD | 77-208 | 38 | 1.3e-33 | 106.8 | In-house | 6-135 (139) | Show / Hide |
Range on Protein: 77-208 Range on HMM: 6-135/139 Sequence Identity: 38% (50 aa) LPRLFIASQDVAYDKSALSVLGVTHILNVAADLPNAFPSDYVYCSVPMYDDEDEVLMQHYSKCQDFIDEAlSKEDGRLLVHCRAGRSRSVSIAVAYMMHK |. |.. |. | ... |. |..|..|||.|.|||.|.. . | |.|. |.... ....... ||||.. |..|| ||||.|| ||| .|.||.|... ldfLyLGsaehasnlqlLkelkitallnvsaelpnvfeelfkyksipvednkkadisslfeeaidfidsv-kkkgGrvlvhCqaGisrsativlayLmke DKsLTVEEALGKIRETRPNADPNAGFFKQLKA | ...||| ... | .|| || .|| kk-vrleeafefvkqrrsiisPnfgfvgqLle |
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| Phosphatase | aque_DUSP19.AA | Subfamily.DSP12.PD | 77-209 | 34 | 6.4e-33 | 104.7 | In-house | 6-138 (143) | Show / Hide |
Range on Protein: 77-209 Range on HMM: 6-138/143 Sequence Identity: 34% (46 aa) LPRLFIASQDVAYDKSALSVLGVTHILNVAADLPNAFPS--DYVYCSVPMYDDEDEVLMQHYSKCQDFIDEALsKEDGRLLVHCRAGRSRSVSIAVAYMM ||.|.... . . ... |. | .||.| |. . . .... .....|...| |..|. .. .||.|.| ...| .|||| || ||||.| .||.| lpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieegl-ekegavlvHClagvSRSvtiviAYlm HKDKsLTVEEALGKIRETRPNADPNAGFFKQLKAL .|.| | .|.|| ...| .... ||.|| .||| kkek-lslekAlklvkekkkeiepNegFleQLklf |
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| Phosphatase | aque_DUSP19.AA | DSPc | 80-212 | 27 | 3.6e-31 | 110.29 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 80-212 Range on HMM: 1-151/151 Sequence Identity: 27% (42 aa) LFIASQDVAY-DKSALSVLGVTHILNVAADLPN---AFPSDYVYCSVP-MYD---------DEDEVLMQHYSKCQDFIDEALSKEDGRLLVHCRAGRSRS |...|. .. |. |...|.||..|.. .|| .|.. | ..| . | ... . |. ... |||| . .. |. ||||.|| ||| LYLGSYPHHMADPAFLQKHGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDC-RQKGGKVLVHCQAGISRS VSIAVAYMMHKDKSLTVEEALGKI-----RETR-PNADPNAGFFKQLKALEIE .....||.| ... ...||. . .. | |. ||..| .|| ..| ACLCIAYLMKYRNM-SYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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| Phosphatase | aque_DUSP19.AA | Subfamily.DSP6.PD | 77-210 | 35 | 7.1e-31 | 97.7 | In-house | 6-139 (141) | Show / Hide |
Range on Protein: 77-210 Range on HMM: 6-139/141 Sequence Identity: 35% (48 aa) LPRLFIASQDVAYDKSALSVLGVTHILNVAADLPNAFPS--DYVYCSVPMYDDEDEVLMQHYSKCQDFIDEALSKEDgRLLVHCRAGRSRSVSIAVAYMM ||.|.. |.. | . .|. |.. ..|||. .|||.| . . | .|. | . |.... . .||||| ||. .|||| || ||||....||.| lpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskks-kvlvhclaGvsrsvtvtlaylm HKdKSLTVEEALGKIRETRPNADPNAGFFKQLKALE .| ..|....| ... ..| || |..||. | kk-lalslndaydlvkkkksnisPnfnfmgqlldfe |
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| Phosphatase | aque_DUSP19.AA | Subfamily.LRR-DSP.PD | 77-210 | 39 | 1.3e-30 | 96.9 | In-house | 6-135 (137) | Show / Hide |
Range on Protein: 77-210 Range on HMM: 6-135/137 Sequence Identity: 39% (52 aa) LPRLFIASQDVAYDKSALSVLGVTHILNVAaDLPNAFPSDYVYCSVPMYDDEDEVLMQHYSKCQDFIDEAlsKEDGRLLVHCRAGRSRSVSIAVAYMMHK ...|.. ... | .|| | ..||||| || |. .| . | .. . | .. ..||. . . |||| .|.| .|.||||| |||....||.|.| idklylgcresamnksilkdnnvthilava-dfkplypdlfkyliidiedvdeadiyqhfkemnafideg--rekggvlihcragvsrsatlviaylmkk dKSLTVEEALGKIRETRPNADPNAGFFKQLKALE .||. .||| . . ||. || || .||| | -nslkfkealdlvikkrpriypnrgfldqlkkfe |
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| Phosphatase | aque_DUSP19.AA | Subfamily.DSP14.PD | 78-210 | 34 | 2e-30 | 96.6 | In-house | 7-136 (138) | Show / Hide |
Range on Protein: 78-210 Range on HMM: 7-136/138 Sequence Identity: 34% (46 aa) PRLFIAsQDVAYDKSALSVLGVTHILNVAADLPNAFPSDYVYCSVPMYDDEDEVLMQHYSKCQDFIDEaLSKEDGRLLVHCRAGRSRSVSIAVAYMMhKD . |... .| .|..|. ..|.|.||. .||. .| . ... |.... |..|. . | |.| ..|..|. |||| ||.||| |...||.| | esLyls-gaaalkkeklkkkkitlivnvttelpetkledvktvkikveDkpeaklaehfdevadkiee-vkkkgGktlvhCvaGvsRsAslvlaylm-ky KSLTVEEALGKIRETRPNADPNAGFFKQLKALE ..|...|| ....|| || ||.||| ..| eklsLreayklvksaRpiirPnvGFwkqlidyE |
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| Phosphatase | aque_DUSP19.AA | Subfamily.Slingshot.PD | 79-209 | 39 | 2.1e-30 | 96.3 | In-house | 8-136 (139) | Show / Hide |
Range on Protein: 79-209 Range on HMM: 8-136/139 Sequence Identity: 39% (50 aa) RLFIASQDVAYDKSALSVLGVTHILNVAADLPNAFPSDYVYCSVPMYDDEDEVLMQHYSKCQDFIDEAlSKEDGRLLVHCRAGRSRSVSIAVAYMMhKDK |.. |. | . |. ||..||||. .. | || .. |... .||.|.. |..|. . .||..| ... ..||||. | ||||. .|| | |. .| hlylGsewnasnleelkengveyilnvtkeidnffpekfkylnirvydeeetdllkhwnetykfieka-kekgskvlvhckmGvsrsastviayam-key SLTVEEALGKIRETRPNADPNAGFFKQLKAL ..|||| ..| | . ||.||.||||. elsleealeyvkerrsiikpnkgflkqlkvy |
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| Phosphatase | aque_DUSP19.AA | Subfamily.DSP10.PD | 76-210 | 38 | 2.2e-30 | 96.3 | In-house | 5-139 (141) | Show / Hide |
Range on Protein: 76-210 Range on HMM: 5-139/141 Sequence Identity: 38% (53 aa) ALPRLFIASQDVAYDKSALSVLGVTHILNVAADLPNAFPS--DYVYCSVPMYDDEDEVLMQHYSKCQDFIDEALsKEDGRLLVHCRAGRSRSVSIAVAYM || |.. .. | ||.||. ||....|||.. .|| | . | .|. | . . | |.... .||.|| |...|.||||.|| |||. ...||.| ilpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieear-krgsrvlvhchaGisrsatvviayv MhKDKSLTVEEALGKIRETRPNADPNAGFFKQLKALE | .||...|| ..| || || .| || .| m-khlslslseaykfvkekrPiisPnlnfmGqllefe |
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| Phosphatase | aque_DUSP19.AA | Family.DSP.PD | 77-212 | 39 | 5.9e-30 | 95.7 | In-house | 111-246 (387) | Show / Hide |
Range on Protein: 77-212 Range on HMM: 111-246/387 Sequence Identity: 39% (55 aa) LPRLFIASQDVAYDKSALSVLGVTHILNVAADlPNAFPS--DYVYCSVPMYDDEDEVLMQHYSKCQDFIDEALsKEDGRLLVHCRAGRSRSVSIAVAYMM ||.|...| . |... .|. ||||.|.|.. | .. | . . |. .|. | . . | .. |. |||.|. .. |. |||| ||..|| .. .||.| lphlylgsllaaknlewlkelgvtkivnltdd-kpqftkelgikylripidDhnapplenlfekaidfieegn-dskgvVlVHCkaGkgRsgtliiaYlm HKdKSLTVEEALGKIRETRP-NADPNAGFFKQLKALEIE .. . || |||| .|. || .. || ||.||||.|| | ks-egltleealdwvrskRpgvitpnqgflkqlkdleke |
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| Phosphatase | aque_DUSP19.AA | Subfamily.DSP8.PD | 77-210 | 34 | 2.4e-28 | 89.8 | In-house | 6-139 (143) | Show / Hide |
Range on Protein: 77-210 Range on HMM: 6-139/143 Sequence Identity: 34% (47 aa) LPRLFIASQDVAYDKSALSVLGVTHILNVAADLPN--AFPSDYVYCSVPMYDDEDEVLMQHYSKCQDFIDEALsKEDGRLLVHCRAGRSRSVSIAVAYMM || |.. || .. |...|. ||....||.. | . .. . .|. |. .| |.... |. .||| | ...|. |||| ||.|||..|.||.| lpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkar-sangkvlvhclaGisrsatvaiayim hKDKSLTVEEALGKIRETRPNADPNAGFFKQLKALE | .....|| ..| || .|| | || | -ktlemsldeayrfvkekrptispnlnflgqLleye |
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| Phosphatase | aque_DUSP19.AA | Subfamily.DSP15.PD | 77-209 | 35 | 1.5e-27 | 87.1 | In-house | 6-135 (138) | Show / Hide |
Range on Protein: 77-209 Range on HMM: 6-135/138 Sequence Identity: 35% (47 aa) LPRLFIASQDVAYDKSALSVLGVTHILNVAaDLPNAFPSDYVYCSVPMYDDEDEVLMQHYSKCQDFIDEALSKeDGRLLVHCRAGRSRSVSIAVAYMMHK || |.. . | ||. |. .|||| . | .. . | | ... | | |....... ||| .. . .| |||| || ||||...|||.| lpGlyvGnfrdakdkeqleenkithilsih-dsakplledikylcikaadsPdqdlskffkesidfihkcrle-ggnvlvhclaGisrsvtlvvayimtv dKSLTVEEALGKIRETRPNADPNAGFFKQLKAL .|. |.|| .. .|. |.||.|| .||. -telswedalkavkaarsvanPnvGfrrqlqef |
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| Phosphatase | aque_DUSP19.AA | Subfamily.STYX.PD | 77-210 | 34 | 1.7e-18 | 57.8 | In-house | 6-144 (146) | Show / Hide |
Range on Protein: 77-210 Range on HMM: 6-144/146 Sequence Identity: 34% (49 aa) LPRLFIASQDVAyDKSALSVL---GVTHILNVAAD-----LPNAFPSDYVYCSVPMYDDEDEVLMQHYSKCQDFIDEALSKeDGRLLVHCRAGRSRSVSI || ||. | || | || |.|||. . . . || .. | . . |. | ..... . ..|||..|.| |..||| || ||| .. lpglflgpysaa-mksklevlkehgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqk-ggkvlvhgnagisrsaal AVAYMMHKdKSLTVEEALGKIRETRPNADPNAGFFKQLKALE .||.| | || ..| | .||.|| .||| | viayimet-yglkyreafayvqerrfcinpnegfvsqlkeye |
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| Phosphatase | aque_DUSP19.AA | Subfamily.STYXL1.PD | 79-210 | 23 | 5.4e-17 | 53.2 | In-house | 9-141 (143) | Show / Hide |
Range on Protein: 79-210 Range on HMM: 9-141/143 Sequence Identity: 23% (32 aa) RLFIASQDVAYDKSALSVLGVTHILNVAAD---LPNAFPSDYVYCSVPMYDDEDEVLMQHYSKCQDFIDEALSkEDGRLLVHCRAGRSRSVSIAVAYMMH .|.. |.... | | .||. | | .. . ... |... |... .. .||.. |. .|| | |||.....||.|. klylGnykqaqnpaikkdlkvkahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkk-egevvlvfsnkGisrsaaviiaylmy KDKsLTVEEALGKIRETRPNADPNAGFFKQLKALE . | .| ..|. .... ..| || .| .||. | skk-itlkkaykylkkckenvkPnrafveqlseWe |
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| Phosphatase | aque_DUSP19.AA | Subfamily.PTPMT1.PD | 121-198 | 31 | 3.1e-13 | 40.7 | In-house | 57-132 (146) | Show / Hide |
Range on Protein: 121-198 Range on HMM: 57-132/146 Sequence Identity: 31% (23 aa) SVPMYDDEDEVLMQHYSKCQDFIDEALSKEDgRLLVHCRAGRSRSVSIAVAYMMHKdKSLTVEEALGKIRETRPNADP ... | . ... .. .||.. ||.. .. |||.|||.|| ... .|.|.| | |. ||| ... ||. qlatvDfteapslekleegvefiekvaskgs-svYvHCkAGrtRsatlvacylmkk-kklspeeavkflkkkRpqirl |
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| Phosphatase | aque_DUSP19.AA | Subfamily.PTPDC1.PD | 143-196 | 37 | 5.4e-10 | 30.0 | In-house | 160-210 (229) | Show / Hide |
Range on Protein: 143-196 Range on HMM: 160-210/229 Sequence Identity: 37% (20 aa) IDEALskEDGRLLVHCRAGRSRSVSIAVAYMMHKDKsLTVEEALGKIRETRPNA .| || |.|.. ||| ||. | .. .|...... || |||. ..|. ||.. vdfal--eegkiavHCHAGlGRtGvliacylvyakr-ltaeeaiklvrskrpks |
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| Phosphatase | aque_DUSP19.AA | Subfamily.PTEN.PD | 136-193 | 25 | 9.1e-09 | 25.9 | In-house | 78-136 (305) | Show / Hide |
Range on Protein: 136-193 Range on HMM: 78-136/305 Sequence Identity: 25% (15 aa) YSKCQDFIDEALSKEDGRL-LVHCRAGRSRSVSIAVAYMMHKDKSLTVEEALGKIRETR ... . .|. |.... . |||.||. |. . .||.... . . .||| |.| leeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadealaiydekR |
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| Phosphatase | aque_DUSP19.AA | Subfamily.CDC14.PD | 145-194 | 30 | 5.5e-08 | 23.6 | In-house | 192-240 (258) | Show / Hide |
Range on Protein: 145-194 Range on HMM: 192-240/258 Sequence Identity: 30% (15 aa) EALSKEDGRLLVHCRAGRSRSVSIAVAYMMHKdKSLTVEEALGKIRETRP |.. | .| . |||.|| | .. .|.... .| .|... .| .|| eitekaeGaiavhCkaGLGrtgtligcylikh-yrftaaetiawlriarP |
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| Phosphatase | aque_DUSP19.AA | Subfamily.R_Nematode_3.PD | 149-196 | 26 | 7e-07 | 19.7 | In-house | 196-248 (267) | Show / Hide |
Range on Protein: 149-196 Range on HMM: 196-248/267 Sequence Identity: 26% (14 aa) KEDGRLLVHCRAGRSRS---VSIAVAY--MMHKDKSLTVEEALGKIRETRPNA | ..||| .| ||| ..| ..| .......|.. . . ..|. |..| ksktpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRaga |
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| Phosphatase | aque_DUSP19.AA | Subfamily.DSP23.PD | 140-195 | 26 | 7.4e-07 | 20.2 | In-house | 56-109 (128) | Show / Hide |
Range on Protein: 140-195 Range on HMM: 56-109/128 Sequence Identity: 26% (14 aa) QDFIDEALSKeDGRLLVHCRAGRSRSVSIAVAYMMhKDKSLTVEEALGKIRETRPN ..|| | .. . ||| |. |. .. |.. | . |. ..|. .|. |. vriveeaekk-eeavgvhcalGlGrtGtllacylv-keeglaaddaiaevrkrrkG |
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| Phosphatase | aque_DUSP19.AA | Subfamily.R_Nematode_2.PD | 145-196 | 28 | 2.5e-06 | 17.8 | In-house | 187-242 (261) | Show / Hide |
Range on Protein: 145-196 Range on HMM: 187-242/261 Sequence Identity: 28% (16 aa) EALSKEDGRLLVHCRAGRSRSVSI-AVAYM---MHKDKSLTVEEALGKIRETRPNA |.. |.. ..||| || |.... ...|. . .|......||| ..|| |... elvkksekPivvhCsaGiGRtmafigteylareveadptieltealkelrehRwkg |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| aque_DUSP19.AA | Protein | None | 217 | None | Fasta, JSON |
| aque_DUSP19.NA | RNA | None | 651 | None | Fasta, JSON |
| aque_DUSP19.AA.PD_72-212 | Protein Phosphatase Domain | None | 141 | None | Fasta, JSON |