Gene aque_DUSP16
aque_DUSP16
Species: A.queenslandica
Alias: aque_DUSP16
External Links:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of aque_DUSP16.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Rhodanese | aque_DUSP16.AA | Rhodanese | 24-93 | 23 | 2e-06 | 22.24 | Pfam | 12-69 (102) | Show / Hide |
Range on Protein: 24-93 Range on HMM: 12-69/102 Sequence Identity: 23% (18 aa) EHYLVIDTRPLEDYERGHIATA-VSYPHDTAASSRSEEEREASLVAFARD--YSSQFYRPENPNPL-VLYG--DRA ..|..||.|| |.||.||| | |. |. .... . . .... .| |.|. .|. PDYVIIDVRPPEEYEKGHIPGAHVNIPW------------------LEEEHDLEELGIKLDKDKPIIVVYCHGNRS |
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| Phosphatase | aque_DUSP16.AA | Family.DSP.PD | 185-325 | 24 | 8.7e-22 | 68.2 | In-house | 106-247 (387) | Show / Hide |
Range on Protein: 185-325 Range on HMM: 106-247/387 Sequence Identity: 24% (35 aa) LPHQITKNVFMGSRVVPMSSHALSKMGMSHVIISEHQDIDMEELKNVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVF-VHGRSRSASVILA .|..|......|| ....|.. |..... .. .. .....|..|. | | ... ..| .. ||... ...|.||| .|..||...| | kpseilphlylgsllaaknlewlkelgvtkivnltddkpqftkelgikylripidDhnapplenlfekaidfieegndskgvVlVHCkaGkgRsgtliia YLMKTLEMNFESSWTHLRSKCWHLIDKSLVFEEQLVQWYREL |||| ...| .....||| . | . | .|| ... |. YlmksegltleealdwvrskRpgvitpnqgflkqlkdlekek |
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| Phosphatase | aque_DUSP16.AA | Subfamily.DSP8.PD | 186-325 | 41 | 1.3e-63 | 203.5 | In-house | 2-142 (143) | Show / Hide |
Range on Protein: 186-325 Range on HMM: 2-142/143 Sequence Identity: 41% (59 aa) PHQITKNVFMGSRVVPMSSHALSKMGMSHVI-ISEHQDIDMEELKNVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVFVH-GRSRSASVILA |..|..|...||.........|.|.|.|.|. |||....|.|.||....|..|||||..|..||.......|||||.|.||.|||... |.||||.|..| ptrilpnlylGsqkdsldeellkklgisyvlnisescpkdvellkesrflriPvkDkyeekllpwfdkalefidkarsangkvlvhclaGisrsatvaia YLMKTLEMNFESSWTHLRSKCwHLIDKSLVFEEQLVQWYREL |.||||||...........|. ..|...|.|..||.....|| yimktlemsldeayrfvkekr-ptispnlnflgqLleyekel |
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| Phosphatase | aque_DUSP16.AA | Subfamily.DSP19.PD | 188-304 | 28 | 4.7e-21 | 65.4 | In-house | 4-120 (139) | Show / Hide |
Range on Protein: 188-304 Range on HMM: 4-120/139 Sequence Identity: 28% (33 aa) QITKNVFMGSRVVPMSSHALSKMGMSHVIiSEHQDIDMEELKNVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVFVH-GRSRSASVILAYLM ........|| | .....|.| .. |.. . ... |...... .. |......| ..... ||..| |..||||| . |.||||||..|||| evkprlylgsqdvaadkeilkklkitHil-nvavgvpnvfpkdftyksieilDlpetkllsylkealdFieearskdgrvlvHCnAGvSRsasvviaylm KTLEMNFESSWTHLRSKC |. |...|.. ..|.. kdeelslekalekvrear |
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| Phosphatase | aque_DUSP16.AA | Subfamily.DSP1.PD | 186-322 | 24 | 6.7e-21 | 65.1 | In-house | 2-137 (139) | Show / Hide |
Range on Protein: 186-322 Range on HMM: 2-137/139 Sequence Identity: 24% (33 aa) PHQITKNVFMGSRVVPMSSHALSKMGMSHVIISEHQdIDMEELKNVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVFVH-GRSRSASVILAY | .| ...||.. . . |......... . .. . . . ||.|....... .| |||.. ...||||| . | ||||...||| pveildfLyLGsaehasnlqlLkelkitallnvsae-lpnvfeelfkyksipvednkkadisslfeeaidfidsvkkkgGrvlvhCqaGisrsativlay LMKTLEMNFESSWTHLRSKCwHLIDKSLVFEEQLVQWY |||. ....| ........ ..|. . | .||... Lmkekkvrleeafefvkqrr-siisPnfgfvgqLlefe |
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| Phosphatase | aque_DUSP16.AA | Subfamily.DSP14.PD | 188-320 | 23 | 5.4e-20 | 62.2 | In-house | 4-134 (138) | Show / Hide |
Range on Protein: 188-320 Range on HMM: 4-134/138 Sequence Identity: 23% (32 aa) QITKNVFMGsRVVPMSSHALSKMGMSHVIISEHQDIDMEeLKNVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVF-VHGRSRSASVILAYLM .||...... .. .. ..|.| ...... . ... |..|...| .|.||..... . .. . |... ...|..||. | |.|||||..||||| eitesLyls-gaaalkkeklkkkkitlivnvttelpetk-ledvktvkikveDkpeaklaehfdevadkieevkkkgGktlvhCvaGvsRsAslvlaylm KTLEMNFESSWTHLRSKcWHLIDKSLVFEEQLVQ | ... . ......|. .| | .||.. kyeklsLreayklvksa-RpiirPnvGFwkqlid |
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| Phosphatase | aque_DUSP16.AA | Subfamily.DSP12.PD | 188-323 | 23 | 6e-20 | 62.1 | In-house | 4-140 (143) | Show / Hide |
Range on Protein: 188-323 Range on HMM: 4-140/143 Sequence Identity: 23% (32 aa) QITKNVFMGSRVVPMSSHALSKMGMSHVIISEHQDI-DMEELKNVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVFV-HGRSRSASVILAYL .|......|.. .. . |... ..||. .. . .... |.|. . .. |...|..| . ..||.......| ||| | |||.....||| eilpglylggleavqerellkelkithvlsvikeelpelqkekgvkskliqilDepeedlLshldeavrFieeglekegavlvHClagvSRSvtiviAYl MKTLEMNFESSWTHLRSKCwHLIDKSLVFEEQLVQWYR ||. ....|. . ...| . | | ||| ... mkkeklslekAlklvkekk-keiepNegFleQLklfek |
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| Phosphatase | aque_DUSP16.AA | Subfamily.STYXL1.PD | 213-322 | 32 | 6.3e-20 | 62.2 | In-house | 31-141 (143) | Show / Hide |
Range on Protein: 213-322 Range on HMM: 31-141/143 Sequence Identity: 32% (36 aa) SHVIISEHQDIDMEELKN-VHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVFV-HGRSRSASVILAYLMKTLEMNFESSWTHLRsKCWHLIDK .|| .| . .. |.. ...|...|.|.|. ..|. . ..||.| . |. |||| .| ||||.||.|||| ..........|. || . . ahvnvssdaekliagladvakllhiavedeneadllerlkevvqfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitlkkaykylk-kckenvkP SLVFEEQLVQWY | ||| .| nrafveqlseWe |
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| Phosphatase | aque_DUSP16.AA | Subfamily.DSP6.PD | 186-321 | 26 | 1.7e-19 | 60.2 | In-house | 2-138 (141) | Show / Hide |
Range on Protein: 186-321 Range on HMM: 2-138/141 Sequence Identity: 26% (37 aa) PHQITKNVFMGSRVVPMSSHALSKMGMSHVIISEH-QDIDMEELKNVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVFVH-GRSRSASVILA | .|......||. . ...|.|.....|. . . || .... .. |..|. .|. . . .|||.| |.. ||| . | ||| .|.|| pveilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkykqipiedhlsqnlakffPeaiefidearskkskvlvhclaGvsrsvtvtla YLMKTLEMNFESSWTHLRSKCWHlIDKSLVFEEQLVQW ||||.|.. ..... ...| . | . | .||... ylmkklalslndaydlvkkkksn-isPnfnfmgqlldf |
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| Phosphatase | aque_DUSP16.AA | Subfamily.Slingshot.PD | 186-319 | 26 | 8.7e-19 | 58.0 | In-house | 2-134 (139) | Show / Hide |
Range on Protein: 186-319 Range on HMM: 2-134/139 Sequence Identity: 26% (35 aa) PHQITKNVFMGSRVVPMSSHALSKMGMSHVIiSEHQDIDMEELKNVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVFV-HGRSRSASVILAY . .| . ...|| . |...|..... ..|| .... |. | |......|. |. . .||.|| ... .|||| |||||...|| ||. askifdhlylGsewnasnleelkengveyil-nvtkeidnffpekfkylnirvydeeetdllkhwnetykfiekakekgskvlvhckmGvsrsastviay LMKTLEMNFESSWTHLRSKCwHLIDKSLVFEEQLV |...|......... ..| | .|| amkeyelsleealeyvkerr-siikpnkgflkqlk |
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| Phosphatase | aque_DUSP16.AA | Subfamily.DSP3.PD | 189-305 | 31 | 3.7e-18 | 56.2 | In-house | 5-131 (148) | Show / Hide |
Range on Protein: 189-305 Range on HMM: 5-131/148 Sequence Identity: 31% (39 aa) ITKNVFMGSRVVPMSSHALSKMGMSHVIISEHQ------DIDMEELKN--VHVLKCPVKDKNDENMLPCWEASCSFIDKAVSE-NGRVLVF-VHGRSRSA ....|..| . | . . | |.|. ||. . .. | | | |. .. | .|.| . .. .| . |||.|.|. ||.||||.| |||| . vypkvyvgdeavakdkekLkklGithvLnaaegkrllkvdtdaefYkdleikylGvevsDvpefdlskyfeeaadfidealsqkngkvlvhcvvGisRsa SVILAYLMKTLEMNFESSWTHLRSKCW .||||| . ... ... .. |.| . tlvlayLmirrkltlkeaiktvrkkre |
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| Phosphatase | aque_DUSP16.AA | DSPc | 185-324 | 21 | 4.5e-16 | 60.63 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 185-324 Range on HMM: 1-172/172 Sequence Identity: 21% (37 aa) LPHQITKNVFMGSRVVPM--SSHALSKMGMSHVI-ISEHQDI---------------DMEELKNVHVLKCP-VKD-------KNDENMLPCWEASCSFID | .||.... || . | .. |.| . ||| .. ... . . .. . . .| . | .|... .... ||. GPSEITPHLYLGSYPHHMEPNPCFLKKHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFIH KAVSENGRVLVF-VHGRSRSASVILAYLMKTLEMNFESSWTHL-----RSKCWHLIDKSLVFEEQLVQWYRE .. ...|.||| .| ||||... |||||. |. .... .. ... | .. | || .|.| DCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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| Phosphatase | aque_DUSP16.AA | Subfamily.DSP10.PD | 188-321 | 28 | 5.7e-16 | 49.0 | In-house | 4-138 (141) | Show / Hide |
Range on Protein: 188-321 Range on HMM: 4-138/141 Sequence Identity: 28% (39 aa) QITKNVFMGSRVVPMSSHALSKMGMSHVI-ISEHQDIDMEELKNVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVFVH-GRSRSASVILAYL .| ...|. . .||...|...|. . . .|| . |. . ||.|.. .|. .|.. ||..| ....|||| | | |||| |..||. silpflllGnekdaadkdaldrlgikyvlnvttsvPnffeekglvrykripvsdsgkqnlkqkfeealefieearkrgsrvlvhchaGisrsatvviayv MKTLEMNFESSWTHLRSKCwHLIDKSLVFEEQLVQW || |.. .. .. ...| | | | ||... mkhlslslseaykfvkekr-PiisPnlnfmGqllef |
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| Phosphatase | aque_DUSP16.AA | DSPc | 193-324 | 24 | 1.5e-14 | 52.48 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 193-324 Range on HMM: 1-151/151 Sequence Identity: 24% (37 aa) VFMGSRVVPM-SSHALSKMGMSHVI-ISE----HQDIDMEELKNVHVLKCP-VKD---------KNDENMLPCWEASCSFIDKAVSENGRVLVF-VHGRS .. || . | . |.| | .||| .. . . .. | ...| |.| ..|. . ... .|||.. ...|.||| .| | LYLGSYPHHMADPAFLQKHGITHVINCTMECPNN---WFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGIS RSASVILAYLMKTLEMNFESSWTHL-----RSKCWHLIDKSLVFEEQLVQWYRE |||....|||||. |. . . .. ... | . | || ...| RSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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| Phosphatase | aque_DUSP16.AA | Subfamily.STYX.PD | 190-320 | 25 | 2.7e-13 | 40.3 | In-house | 6-142 (146) | Show / Hide |
Range on Protein: 190-320 Range on HMM: 6-142/146 Sequence Identity: 25% (35 aa) TKNVFMGSRVVPMSSH--ALSKMGMSHVIISeHQDIDMEELK-----NVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVFV-HGRSRSASVI .|.| | |. | . |..|.. |.|. . .| . . | | |. ||.. .|||..... |.||| |||||....||. lpglflgpysaamksklevlkehgithivci-rqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalv LAYLMKTLEMNFESSWTHLRSKCWhLIDKSLVFEEQLVQ |.| ... ....... . . |. | .|| . iayimetyglkyreafayvqerrf-cinpnegfvsqlke |
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| Phosphatase | aque_DUSP16.AA | Subfamily.LRR-DSP.PD | 186-321 | 23 | 2.4e-12 | 37.2 | In-house | 2-134 (137) | Show / Hide |
Range on Protein: 186-321 Range on HMM: 2-134/137 Sequence Identity: 23% (32 aa) PHQITKNVFMGSRVVPMSSHALSKMGMSHVI-ISEHQDIDMEELKNVHVlkcPVKDKNDENMLPCWEASCSFIDKAVsENGRVLVFV-HGRSRSASVILA |..| .....|.| | | . ...|.. ... . . . .| . . ..| .. .. .. .|||. |.| ||.| ||||....||||| pdliidklylgcresamnksilkdnnvthilavadfkplypdlfkylii---diedvdeadiyqhfkemnafidegr-ekggvlihcragvsrsatlvia YLMKTLEMNFESSWTHLRSKcWHLIDKSLVFEEQLVQW ...|. . .| | | .|| .. ylmkknslkfkealdlvikk-rpriypnrgfldqlkkf |
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| Phosphatase | aque_DUSP16.AA | Subfamily.DSP15.PD | 188-322 | 22 | 2.7e-12 | 37.2 | In-house | 4-136 (138) | Show / Hide |
Range on Protein: 188-322 Range on HMM: 4-136/138 Sequence Identity: 22% (30 aa) QITKNVFMGSRVVPMSSHALSKMGMSHVIiSEHQDiDMEELKNVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVF-VHGRSRSASVILAYLM .. . ...|. .. |.. ..|.. | |.. |.... | ...| | .. .. | || |. |.| ||| . | |||... ||.| kvlpGlyvGnfrdakdkeqleenkithil-sihds-akplledikylcikaadsPdqdlskffkesidfihkcrleggnvlvhclaGisrsvtlvvayim KTLEMNFESSWTHLRSkCWHLIDKSLVFEEQLVQWY |...| . . ... . . . . |..|| ... tvtelswedalkavka-arsvanPnvGfrrqlqefe |
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| Phosphatase | aque_DUSP16.AA | Subfamily.PTPMT1.PD | 230-308 | 29 | 1.3e-10 | 31.6 | In-house | 52-131 (146) | Show / Hide |
Range on Protein: 230-308 Range on HMM: 52-131/146 Sequence Identity: 29% (23 aa) NVHVLKCPVKDKNDENMLPCWEASCSFIDKAVSENGRVLVFVH-GRSRSASVILAYLMKTLEMNFESSWTHLRSKCWHLI |. |. ...| . | | . .||.| |.. .| | ||.|||... .||||. ... |.....|..| .. GveqlqlatvDfteapslekleegvefiekvaskgssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpqir |
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Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| aque_DUSP16.AA | Protein | None | 333 | None | Fasta, JSON |
| aque_DUSP16.NA | RNA | None | 999 | None | Fasta, JSON |
| aque_DUSP16.AA.PD2_185-324 | Protein Phosphatase Domain | None | 140 | None | Fasta, JSON |