• Phosphatome.Net

Gene aque_PRL

aque_PRL
Species: A.queenslandica
Alias: aque_PRL
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: PRL
Protein domain

Protein domains of aque_PRL.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase aque_PRL.AA Subfamily.PRL.PD 29-166 59 6.5e-70 224.9 In-house 2-139 (140) Show / Hide 
Range on Protein: 29-166
Range on HMM: 2-139/140
Sequence Identity: 59% (82 aa)

KFLIINNPTSATLPNFINELEKNQAKIVVRCCEPSYSSEPLKAKGIDVIDLQFDDGGSPPEDIIRQWLVIVKDTFEKSPNCSLAVHCVAGLGRAPVLVAI
.|||...|. .|...||.||.|...| |||.|||||..| ||..||.|.||.||||..||......|| ..|..|...|....||||||||||||||||.
rflildepsdetvekfieelkkenvkevvrvcepsydaeklkeegievldlafddGavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlval

ALIEKGMKYHEAVDFIRNKRRGAINKRQLDFLENYKSK
||||.||||..||.|||.|||||||..||.|||.||.|
alieaGmkyedavefirekrrgainskqlkflekykak
Phosphatase aque_PRL.AA Subfamily.CDC14.PD 43-164 27 5.8e-21 66.8 In-house 138-255 (258) Show / Hide 
Range on Protein: 43-164
Range on HMM: 138-255/258
Sequence Identity: 27% (33 aa)

NFINELEKNQAKIVVRCCEPSYSSEPLKAKGIDVIDLQFDDGGSPPEDIIRQWLVIVKDTfekspNCSLAVHCVAGLGRAPVLVAIALIE-KGMKYHEAV
....   ||. . .||  .  |  .  ...|..  || | ||. |.. |....| |. ..     . ..|||| |||||  .|..  ||... .|.. ..
klleyfrknnvttivrLnkklYdakkftdaGfahlDlffiDGtvPsdailkkfleiteka-----eGaiavhCkaGLGrtgtligcylikhyrftaaeti

DFIRNKRRGAINKRQLDFLENYK
|  | | .   |  .|.. .   
awlriarPGsvigpqqtylvekq
Phosphatase aque_PRL.AA Family.DSP.PD 30-164 23 8.9e-21 66.1 In-house 113-241 (387) Show / Hide 
Range on Protein: 30-164
Range on HMM: 113-241/387
Sequence Identity: 23% (33 aa)

FLIINNPTSAtlpNFINELEKNQAKIVVRCCEPSYS--SeplkAKGIDVIDLQFDDGGSPPEDIIrqWLVIVKdTFEK--SPNCSLAVHCVAGLGRAPVL
.|.. ..  |   .   .|.... . .|.... . .  .     .|| ......||...|| ...  .  ...   |.  ...   .||| ||.||..|.
hlylgsllaa---knlewlkelgvtkivnltddkpqftk----elgikylripidDhnapplenl--fekaid-fieegndskgvVlVHCkaGkgRsgtl

VAIALIEK-GMKYHEAVDFIRNKRRGAINKRQLdFLENYK
.. |... |....||.|..| ||.| |. .|  ||...| 
iiaYlmksegltleealdwvrskRpgvitpnqg-flkqlk
Phosphatase aque_PRL.AA Subfamily.PTPDC1.PD 63-164 34 1.1e-14 45.9 In-house 124-224 (229) Show / Hide 
Range on Protein: 63-164
Range on HMM: 124-224/229
Sequence Identity: 34% (36 aa)

SYSSEPLKAKGIDVIDLQFDDGGSPPEDIIrqwLVIVKDTFEKSPNCSLAVHCVAGLGRAPVLVAIALI-EKGMKYHEAVDFIRNKRRGAINKR-QLDFL
||. | |. .|| .    ..| |... . |   | |||       .  .|||| |||||  ||.|  |.  | .. .||....|.||  .|. | |....
sYdpeelmrqgiyfynfglkDygvasleri---LdivkvvdfaleegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtreqvelv

ENYK
|...
eeFa
Phosphatase aque_PRL.AA Subfamily.DSP23.PD 71-158 26 1.6e-11 35.9 In-house 31-118 (128) Show / Hide 
Range on Protein: 71-158
Range on HMM: 31-118/128
Sequence Identity: 26% (24 aa)

AKGIDVIDLQFDDGGSPPEDIIRQWLVIVKDTFEKspNCSLAVHCVAGLGRAPVLVAIALI-EKGMKYHEAVDFIRNKRRGAINKR-QLD
|... .  .. .|   |  . . ... ||... .|  . ...|||. ||||.  |.|  |. |.|.   .|.  .|..|.|.|. . | .
apsltlrridipdfcPPaleqvarlvriveeaekk--eeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsietveqek
Phosphatase aque_PRL.AA Subfamily.RNGTT.PD 63-163 28 2e-11 35.3 In-house 33-133 (140) Show / Hide 
Range on Protein: 63-163
Range on HMM: 33-133/140
Sequence Identity: 28% (28 aa)

SYSSEPLKAKGIDVIDLQF-DDGGSPPEDIIRQWLVIVKDTFEKSPNCSLAVHCVAGLGRAPVLVAIALIEKG-MKYHEAVDFIRNKRRGAINKRQldFL
|  | |. .|.  | ||    | .| .. ..... .||. ..|.|.. ..|||  |  |.  |..  |.||  .. ..||.   . || |..  .|... 
yydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayLvekedwsveaavalfakarppGiyked--yl

ENY
   
kel
Phosphatase aque_PRL.AA Subfamily.PTPMT1.PD 54-165 27 4.7e-11 34.2 In-house 27-145 (146) Show / Hide 
Range on Protein: 54-165
Range on HMM: 27-145/146
Sequence Identity: 27% (33 aa)

KIVVRCCEPS------YSSEPLKAKGIDVIDLQFDDGGS-PPEDIIRQWLVIVKDTFEKSpnCSLAVHCVAGLGRAPVLVAIALI-EKGMKYHEAVDFIR
| || ..|         |.|  |..|.. . |   | .  |  . ... . ..... .|    |. ||| || .|.  |||  |. .| .. .|||.|..
kavvslneeyelkalansteewkklGveqlqlatvDfteapslekleegvefiekvaskg--ssvYvHCkAGrtRsatlvacylmkkkklspeeavkflk

NKRRGA-INKRQLDFLENYKS
.||.   ....|.. |...|.
kkRpqirlkskqwralqefke
Phosphatase aque_PRL.AA Subfamily.PTEN.PD 44-148 22 3.7e-09 27.8 In-house 33-136 (305) Show / Hide 
Range on Protein: 44-148
Range on HMM: 33-136/305
Sequence Identity: 22% (24 aa)

FINELEKNQAKIVVRCCEPSYSSEPLkakGIDVIDLQFDDGGSPPEDIIRQWLVIVKDTFEKSPNCSLAVHCVAGLGRAPVLVAIALIEKGMKYH--EAV
...   |.. |. . ... .. .  .      |.   |||  .|. .....    |.   ... .   |||| || ||. |...  |...|.| .  ||.
llltvykgkgklrilnargekedsdf---dgrvavypfdDhnpptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadeal

DFIRNKR
..  .||
aiydekR
Phosphatase aque_PRL.AA Subfamily.DSP11.PD 63-155 21 1.2e-07 23.1 In-house 34-129 (141) Show / Hide 
Range on Protein: 63-155
Range on HMM: 34-129/141
Sequence Identity: 21% (20 aa)

SYSSEPLKAKGIDVIDLQFDDGGSPPEDIIRQWLVIVKDTFE--KSPNCSLAVHCVAGLGRAPVLVAIALIE-KGMKYHEAVDFIRNKRRGAINKR
|. . |...|.    |.      | .......   ||.  |  |  .  ..|||  |. |.  |.   ||. .|.. ..|..   . |....    
yykkkeltdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaieafeearGhslere
Phosphatase aque_PRL.AA Subfamily.DSP3.PD 107-162 30 1.5e-07 22.9 In-house 88-144 (148) Show / Hide 
Range on Protein: 107-162
Range on HMM: 88-144/148
Sequence Identity: 30% (17 aa)

PNCSLAVHCVAGLGRAP-VLVAIALIEKGMKYHEAVDFIRNKRRGAINKRQLDFLEN
|  . ||||.|. |.. . .|  .| . .. .||.  .|.||    |.  |  | . 
kngkvlvhcvvGisRsatlvlayLmirrkltlkeaiktvrkkreilPneGflkqLle
Phosphatase aque_PRL.AA Subfamily.R_Nematode_3.PD 109-156 25 4e-07 21.1 In-house 199-253 (267) Show / Hide 
Range on Protein: 109-156
Range on HMM: 199-253/267
Sequence Identity: 25% (14 aa)

CSLAVHCVAGLGRAPVLVAIAL-IE------KGMKYHEAVDFIRNKRRGAINKRQ
.. |||..| .|. .|.|| | ..      . ... . .. .|..| |||.. . 
tpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtel
Phosphatase aque_PRL.AA Subfamily.DSP1.PD 108-149 33 4.3e-07 21.5 In-house 79-121 (139) Show / Hide 
Range on Protein: 108-149
Range on HMM: 79-121/139
Sequence Identity: 33% (14 aa)

NCSLAVHCVAGLGRAPVLVAIALI-EKGMKYHEAVDFIRNKRR
.    ||| ||. |.  .| . |. || ....|| .|....| 
gGrvlvhCqaGisrsativlayLmkekkvrleeafefvkqrrs
Phosphatase aque_PRL.AA Subfamily.DSP8.PD 105-161 40 6e-07 21.0 In-house 78-133 (143) Show / Hide 
Range on Protein: 105-161
Range on HMM: 78-133/143
Sequence Identity: 40% (24 aa)

KSPNCSLAVHCVAGLGRAPVlVAIALIEKG--MKYHEAVDFIRNKRrGAINKrQLDFLE
.| |..  ||| ||  |..  |||| | |   |.. ||  |...||  .|.. .| ||.
rsangkvlvhclaGisrsat-vaiayimktlemsldeayrfvkekr-ptisp-nlnflg
Phosphatase aque_PRL.AA Subfamily.RB.PD 97-144 27 1.1e-06 19.7 In-house 181-229 (261) Show / Hide 
Range on Protein: 97-144
Range on HMM: 181-229/261
Sequence Identity: 27% (13 aa)

VIVKDTFEKS-PNCSLAVHCVAGLGRAPVLVAIALIEKGMKYHEAVDFI
|... ||.  .  . ||| ||.||. . .|.  . . .. .. || .  
rtvreaiekkaskkPivvHCsaGvGRtGtfialdrllqaieendyvdvf
Phosphatase aque_PRL.AA Subfamily.N13.PD 101-155 26 1.1e-06 19.9 In-house 185-244 (259) Show / Hide 
Range on Protein: 101-155
Range on HMM: 185-244/259
Sequence Identity: 26% (16 aa)

DTFEKsPNCSLAVHCVAGLGRAPVLVAIALI------EKGMKYHEAVDFIRNKRRGAINKR
....  .  ..||| ||.||. ||..|  .      .| .. .| |  .|..|.| .  . 
rllqt-dagPivvhcsaGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtk
Phosphatase aque_PRL.AA Subfamily.DSP19.PD 104-151 21 1.5e-06 19.6 In-house 73-123 (139) Show / Hide 
Range on Protein: 104-151
Range on HMM: 73-123/139
Sequence Identity: 21% (11 aa)

EKSP--NCSLAVHCVAGLGRAPV-LVAIALIEKGMKYHEAVDFIRNKRRGA
|..   .  . ||| ||  |..   .|  . .. .....|.. .|..|. .
eearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpci
Phosphatase aque_PRL.AA PTPc_motif 72-167 18 2e-06 22.15 SMART 1-92 (92) Show / Hide 
Range on Protein: 72-167
Range on HMM: 1-92/92
Sequence Identity: 18% (19 aa)

KGIDVIDLQFDDG-----GSPPEDIIRQWLVIVKDTFEKSPNCSLAVHCVAGLGRAPVLVAIALIEKGMKYHEAVDFIRNKRRGAINKRQLDFLENYKSK
.   .  ..  |      | |  | | ...  |..        .. ||| || ||. ...|| ..   .   . |  .|. |.|..   .      .   
TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK--------PIVVHCSAGCGRTGTFCAIDMMMQQVDIFQTVKEMRKQRPGMVQTEEQYIFCYRCIL

D
.
E
Phosphatase aque_PRL.AA Subfamily.STYX.PD 84-153 33 2.2e-06 19.1 In-house 61-131 (146) Show / Hide 
Range on Protein: 84-153
Range on HMM: 61-131/146
Sequence Identity: 33% (24 aa)

GGSPPEDIIRqWLVIVKDTFEKSP--NCSLAVHCVAGLGRAPVLVAIALIE-KGMKYHEAVDFIRNKRRgAIN
.. |.||| .|  ||.  ..|      . ||  ||. |.  ||   ..|  |.|| ||  .....|   ||  
adntveniir-ylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrf-cin
Phosphatase aque_PRL.AA Subfamily.Slingshot.PD 105-162 28 2.9e-06 18.6 In-house 76-132 (139) Show / Hide 
Range on Protein: 105-162
Range on HMM: 76-132/139
Sequence Identity: 28% (17 aa)

KSPNCSLAVHCVAGLGR-APVLVAIALIEKGMKYHEAVDFIRNKRRgaINKRQLDFLEN
|. . .. |||  |. | | ...| |. | .....||.......|.  | |    ||..
kekgskvlvhckmGvsrsastviayamkeyelsleealeyvkerrs--iikpnkgflkq
Phosphatase aque_PRL.AA Subfamily.N12.PD 100-138 32 3.3e-06 17.9 In-house 191-229 (270) Show / Hide 
Range on Protein: 100-138
Range on HMM: 191-229/270
Sequence Identity: 32% (12 aa)

KDTFEKSPNCSLAVHCVAGLGRAPVLVAIALIEKGMKYH
....| .  |.||| || ||. ...|| .. . .| .  
vrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkae
Phosphatase aque_PRL.AA Subfamily.N5_RR.PD 106-145 28 4.2e-06 17.8 In-house 195-234 (265) Show / Hide 
Range on Protein: 106-145
Range on HMM: 195-234/265
Sequence Identity: 28% (11 aa)

SPNCSLAVHCVAGLGRAPVLVAIALIEKGMKYHEAVDFIR
.   . ||| ||.||. . .|| .  . .. .. || .. 
aklaPvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlk
Phosphatase aque_PRL.AA Subfamily.RA.PD 95-145 28 4.6e-06 17.7 In-house 185-235 (266) Show / Hide 
Range on Protein: 95-145
Range on HMM: 185-235/266
Sequence Identity: 28% (14 aa)

WLVIVKDTFEKSPNCSLAVHCVAGLGRAPVLVAIALIEKGMKYHEAVDFIR
|  || . ..| | ...||| || ||.  ....  . . .|  . .|  . 
llkkvkklqqqsanhpivvhcsaGvGrtGtfivldavlervkaerkldvfe
Phosphatase aque_PRL.AA Subfamily.N_Nematode_1.PD 83-138 35 5.1e-06 17.5 In-house 175-226 (265) Show / Hide 
Range on Protein: 83-138
Range on HMM: 175-226/265
Sequence Identity: 35% (19 aa)

DGGSPPEDIIRQWLvIVKDTFEKSPncsLAVHCVAGLGRAPVLVAIALIEKGMKYH
| | || |.    | . .   .|.|   ..||| ||.||.  .|||..|   .   
drGvPpadlaalel-leavrgskgP---ivvhCsaGiGrtGtivaieyildklleg
Phosphatase aque_PRL.AA Subfamily.LRR-DSP.PD 110-154 30 5.6e-06 17.7 In-house 79-125 (137) Show / Hide 
Range on Protein: 110-154
Range on HMM: 79-125/137
Sequence Identity: 30% (14 aa)

SLAVHCVAGLGRAPVL-VAIALIEKGMKYHEAVDFIRNKRRGA-INK
. .|| ||. |.  | .|  . .. .|..||.|.. .||     |. 
gvlihcragvsrsatlviaylmkknslkfkealdlvikkrpriypnr
Phosphatase aque_PRL.AA Subfamily.DSP10.PD 106-149 29 5.9e-06 17.7 In-house 79-123 (141) Show / Hide 
Range on Protein: 106-149
Range on HMM: 79-123/141
Sequence Identity: 29% (13 aa)

SPNCSLAVHCVAGLGRAP-VLVAIALIEKGMKYHEAVDFIRNKRR
. . .. ||| ||. |.  | .|  .  ...  .||  |...|| 
krgsrvlvhchaGisrsatvviayvmkhlslslseaykfvkekrP
Phosphatase aque_PRL.AA Subfamily.R_Anemone_2.PD 104-144 33 1e-05 16.8 In-house 190-230 (262) Show / Hide 
Range on Protein: 104-144
Range on HMM: 190-230/262
Sequence Identity: 33% (13 aa)

EKSPNCSLAVHCVAGLGRAPVLVAIALIEKGMKYHEAVDFI
..| .  ..||| ||.||. | .|.  . . .|  . ||  
qesgagpivvhcsaGvGrtGvfiavdillerikaealvdvf
Phosphatase aque_PRL.AA Subfamily.DSP6.PD 106-149 27 1e-05 16.7 In-house 79-123 (141) Show / Hide 
Range on Protein: 106-149
Range on HMM: 79-123/141
Sequence Identity: 27% (12 aa)

SPNCSLAVHCVAGLGRAP-VLVAIALIEKGMKYHEAVDFIRNKRR
| .... ||| ||. |.  | .|  . .. .   .| |....|. 
skkskvlvhclaGvsrsvtvtlaylmkklalslndaydlvkkkks
Sequence
Name Sequence Type Origin Length Description Download
aque_PRL.AA Protein None 173 None Fasta, JSON
aque_PRL.NA RNA None 519 None Fasta, JSON
aque_PRL.AA.PD_52-167 Protein Phosphatase Domain None 116 None Fasta, JSON