• Phosphatome.Net

Gene aque_RNGTT-A

aque_RNGTT-A
Species: A.queenslandica
Alias: aque_RNGTT-A
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: RNGTT
Protein domain

Protein domains of aque_RNGTT-A.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase aque_RNGTT-A.AA Subfamily.RNGTT.PD 76-197 57 4e-53 168.8 In-house 2-139 (140) Show / Hide 
Range on Protein: 76-197
Range on HMM: 2-139/140
Sequence Identity: 57% (79 aa)

KERFPPSVLTSYRDTY--RIGLVIDLTNTSRYYDKREL---------LQC-----APDVEKVKEFQMVCGEFFKDHPYGVVGVHCTHGFNRTGFLIVSYL
.|.| |..|.||..|.  ..|||||||||||||||.||         |||     ||. |..|.|.... ||.|..|. |.||||||||||||||||.||
eeafepemlksylktlkvklglvidltntsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayL

IDVECWDLEAAVATFSVARPPGIYKEHYLHELAGRYAD
...|.|..|||||.|. |||||||||.||.||. ||.|
vekedwsveaavalfakarppGiykedylkelfkryed
MRNA_cap_enzyme aque_RNGTT-A.AA mRNA_cap_enzyme 262-451 34 5.6e-87 207.97 Pfam 1-213 (213) Show / Hide 
Range on Protein: 262-451
Range on HMM: 1-213/213
Sequence Identity: 34% (73 aa)

QPVSMDV-QNIRFLNEKPYRVSWKADGTRYMLYIKGK---GQ---IYLIDRDNSVFNSPNITFLSRKR-EGEH----LRDCVADSELVLDKVDGA----V
|||||.  .|. || ...|.|.||.||.|||..| ..   |     |.||||....  .|..|  ... .||     . .   | |...|.. .     .
QPVSMSRRENMKFLKQNYYYVCWKTDGMRYMMFITDHPEYGEFKGCYMIDRDMNYYHVENMRFPCKYNKWGESLDKHHHYTLLDGEMCIDTIPMQETQCQ

RPRLLIYDIMMFEGSKDVARCDHQ--RRMLCIDRELIMPREEA--AKRGIIDKIREPFSVRAKQFWDVSESRMIL---EKYAPTLTHENDGLIYNPTNEP
.|| ||||.....|   |  ..     |  .| ||.| || ..  .| .....  .||||| | .|| . |. ..   .| .|.| ||.||||. ....|
QPRYLIYDCVAINGQCRVMQWPFYSRKRWEMIKREIIKPRNHNMKFKTHWYRYDMFPFSVRFKDMWDNWHSEKLVYYFHKFIPHLCHEIDGLIFQCWDTP

YKPGQCKDLLIWK
|.|| |..|. ||
YVPGRCQNLFKWK
Phosphatase aque_RNGTT-A.AA Subfamily.DSP11.PD 78-192 41 7.1e-27 83.9 In-house 5-136 (141) Show / Hide 
Range on Protein: 78-192
Range on HMM: 5-136/141
Sequence Identity: 41% (54 aa)

RFPPSVLTS-YRD-TYRIGLVIDLTNTSRYYDKRELLQC-------------APDVEKVKEFQMVCGEFF--KDHPYGVVGVHCTHGFNRTGFLIVSYLI
|| |. | .  ..  ...||||||||| |||.|.|| .               |. |.||.|. .  ||   ...   ..||||||| ||||.||  |||
rfapedlleklqeknkklGLvidltntdryykkkeltdegvkykklncpGhevpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCryli

DVECWDLEAAVATFSVARPPGIYKEHYLHELA
||| .. | |. .|. ||   . .|.||..| 
dvegyspedaieafeearGhslerenyledLk
Phosphatase aque_RNGTT-A.AA Family.DSP.PD 114-191 33 8.9e-16 48.0 In-house 163-240 (387) Show / Hide 
Range on Protein: 114-191
Range on HMM: 163-240/387
Sequence Identity: 33% (27 aa)

CAPDVEKVkeFQMVCGeFFKD--HPYGVVGVHCTHGFNRTGFLIVSYLIDVECWDLEAAVATFSVARPpGIYK--EHYLHEL
||..|..  |. ..  | ..   . ||| |||..| .|.| ||. ||.  | . ||.|.. .. .|| |. .  ...|..| 
napplenl--fekaid-fieegndskgvVlVHCkaGkgRsgtliiaYlmksegltleealdwvrskRp-gvitpnqgflkql
Phosphatase aque_RNGTT-A.AA Subfamily.DSP23.PD 114-180 33 8.8e-10 28.7 In-house 45-109 (128) Show / Hide 
Range on Protein: 114-180
Range on HMM: 45-109/128
Sequence Identity: 33% (22 aa)

CAPDVEKVKEFQMVCGEFFKDHpyGVVGVHCTHGFNRTGFLIVSYLIDVECWDLEAAVATFSVARPP
| | .|.|...  .. |  | .  . |||||  |. ||| |.  ||.  |    . |.|     |. 
cPPaleqvarlvriveeaekke--eavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkG
Phosphatase aque_RNGTT-A.AA Subfamily.PTEN.PD 115-178 29 3.5e-08 23.0 In-house 72-136 (305) Show / Hide 
Range on Protein: 115-178
Range on HMM: 72-136/305
Sequence Identity: 29% (19 aa)

APDVEKVKEFQMVCGEFFKDHPYGVVGVHCTHGFNRTGFLIVSYLIDVECWDL-EAAVATFSVAR
.| .| ..|.     .. |     || |||  |  ||| .|..||.     .  . |.| .. .|
pptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadealaiydekR
Phosphatase aque_RNGTT-A.AA Subfamily.CDC14.PD 116-182 29 4.4e-08 23.0 In-house 182-243 (258) Show / Hide 
Range on Protein: 116-182
Range on HMM: 182-243/258
Sequence Identity: 29% (20 aa)

PDVEKVKEFQMVCGEFfkdhpYGVVGVHCTHGFNRTGFLIVSYLIDVECWDLEAAVATFSVARPPGI
|. . .|.|  .. .       | . |||  |  ||| || .|||       . ..| . .|||  .
Psdailkkfleiteka-----eGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPGsv
Phosphatase aque_RNGTT-A.AA Subfamily.PTPDC1.PD 138-185 36 1.1e-07 21.4 In-house 167-214 (229) Show / Hide 
Range on Protein: 138-185
Range on HMM: 167-214/229
Sequence Identity: 36% (17 aa)

GVVGVHCTHGFNRTGFLIVSYLIDVECWDLEAAVATFSVARPPGIYKE
| ..|||  |  ||| || .||. ..  . | |. .    ||  |.  
gkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtr
Phosphatase aque_RNGTT-A.AA DSPc 138-170 33 2e-06 24.18 Pfam 86-118 (151) Show / Hide 
Range on Protein: 138-170
Range on HMM: 86-118/151
Sequence Identity: 33% (11 aa)

GVVGVHCTHGFNRTGFLIVSYLIDVECWDLEAA
| | |||..| .|.. |.. ||..  ..... |
GKVLVHCQAGISRSACLCIAYLMKYRNMSYNEA
Phosphatase aque_RNGTT-A.AA Subfamily.DSP12.PD 138-179 30 3e-06 17.3 In-house 82-123 (143) Show / Hide 
Range on Protein: 138-179
Range on HMM: 82-123/143
Sequence Identity: 30% (13 aa)

GVVGVHCTHGFNRTGFLIVSYLIDVECWDLEAAVATFSVARP
| | |||. |  |   ... ||.  | ..|| |. . . ...
gavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekkk
Phosphatase aque_RNGTT-A.AA Subfamily.PRL.PD 116-163 36 3.3e-06 16.9 In-house 60-107 (140) Show / Hide 
Range on Protein: 116-163
Range on HMM: 60-107/140
Sequence Identity: 36% (17 aa)

PDVEKVKEFQMVCGEFFKDHPYGVVGVHCTHGFNRTGFLIVSYLIDVE
|  | |.|.  .. | ||..|  .|.|||  |. |.  |.   ||.  
PpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalalieaG
Phosphatase aque_RNGTT-A.AA Subfamily.TPIP.PD 116-165 30 3.9e-06 16.5 In-house 16-65 (245) Show / Hide 
Range on Protein: 116-165
Range on HMM: 16-65/245
Sequence Identity: 30% (15 aa)

PDVEKVKEFQMVCGEFFKDHPYGVVGVHCTHGFNRTGFLIVSYLIDVECW
| .|..  |     |...  .  || .||  | .||| .. ..||  | .
PtleelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliaseif
Phosphatase aque_RNGTT-A.AA Subfamily.DSP19.PD 130-180 32 5e-06 16.3 In-house 70-122 (139) Show / Hide 
Range on Protein: 130-180
Range on HMM: 70-122/139
Sequence Identity: 32% (17 aa)

EFFKDH--PYGVVGVHCTHGFNRTGFLIVSYLIDVECWDLEAAVATFSVARPP
.| ..     |.| |||  |  |.  ....||.  |  .|| |. .   |||.
dFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpc
MRNA_cap_C aque_RNGTT-A.AA mRNA_cap_C 457-549 25 9.6e-11 39.98 Pfam 7-138 (138) Show / Hide 
Range on Protein: 457-549
Range on HMM: 7-138/138
Sequence Identity: 25% (34 aa)

FHLNIITEK---KFGML---EEKKAQL-LV-----------GSERCE---KIFSYLDL--------QVNKDAKKHSKKIIECSF-VNN----K--WKFLR
| |....|.   . |||    ...  | ..           |   |.   |.     .         . .| |. . ||.||.. |.|       |.|.|
FMLKMCFECIGGEDGMLDRFQQWRGYLDYMEMPNFQKGRWWGGYNCPFFCKMYVFNKMRIFDIEWEKWTNDEKPYNNKIVECTWLVDNKQKGRPEWVFMR

VRTDKGFPDSIETAKSICI---DSVNEDKLLE
.|||| .| .| ||...|    | | .. |.|
FRTDKSNPNHINTARKVCYSIEDNVTKEYLFE
Sequence
Name Sequence Type Origin Length Description Download
aque_RNGTT-A.AA Protein None 589 None Fasta, JSON
aque_RNGTT-A.NA RNA None 1767 None Fasta, JSON
aque_RNGTT-A.AA.PD_75-197 Protein Phosphatase Domain None 123 None Fasta, JSON