aque_RNGTT-B
Species: A.queenslandica
Alias: aque_RNGTT-B
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: DSP
Subfamily: RNGTT
Protein domain

Protein domains of aque_RNGTT-B.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase aque_RNGTT-B.AA Subfamily.RNGTT.PD 43-180 56 3e-60 191.7 In-house 3-139 (140) Show / Hide
Range on Protein: 43-180
Range on HMM: 3-139/140
Sequence Identity: 56% (78 aa)

NRFPLSMLIAFTECIpGHRMGLVIDLTKTSRYYDKRELLKCGIGHHKITCEGYGAAPNAEQVKEFQTLCVNFFKDHPDDIIGVHCTHGFNRTGFLIVSYL
..|  .||.....    ...|||||||.|||||||.|| | |. ..|. |.| | ||. ||.|.|..|. .|.|..||..|||||||||||||||||.||
eafepemlksylktl-kvklglvidltntsryydkeelekegvkyiklqcrGrGeaPtkeqtklfiklvkeflkkkPdevigvhCthGfnrtGflivayL

IDVECWDLESAVATFSMARPPGIYKEHYLHELAGRYAD
...|.|..|.|||.|..|||||||||.||.||. ||.|
vekedwsveaavalfakarppGiykedylkelfkryed

MRNA_cap_enzyme aque_RNGTT-B.AA mRNA_cap_enzyme 272-461 35 4.5e-92 220.22 Pfam 1-213 (213) Show / Hide
Range on Protein: 272-461
Range on HMM: 1-213/213
Sequence Identity: 35% (75 aa)

QPVSMDV-QNIRFLNEKPYRVSWKADGTRYMLYIKDK---GH---IYLIDRDNSVFNSPNITFLSRKR-EGEH----LRDCVADSELVLDKVDGA----V
|||||.  .|. || ...|.|.||.||.|||..| |.   |     |.||||....  .|..|  ... .||     . .   | |...|.. .     .
QPVSMSRRENMKFLKQNYYYVCWKTDGMRYMMFITDHPEYGEFKGCYMIDRDMNYYHVENMRFPCKYNKWGESLDKHHHYTLLDGEMCIDTIPMQETQCQ

RPRLLIYDIMMFEGSKDVAKCDHQ--RRMLCIDRELIMPREEA--AKRGIIDKIREPFSVRAKQFWDVSESRMIL---ESYVPKLTHENDGLIYNPTNQP
.|| ||||.....|   | ...     |  .| ||.| || ..  .| .....  .||||| | .|| . |. ..   .. .|.| ||.||||. ....|
QPRYLIYDCVAINGQCRVMQWPFYSRKRWEMIKREIIKPRNHNMKFKTHWYRYDMFPFSVRFKDMWDNWHSEKLVYYFHKFIPHLCHEIDGLIFQCWDTP

YKPGQCQDLLKWK
|.|| ||.|.|||
YVPGRCQNLFKWK

Phosphatase aque_RNGTT-B.AA Subfamily.DSP11.PD 59-175 46 3.4e-37 117.1 In-house 19-136 (141) Show / Hide
Range on Protein: 59-175
Range on HMM: 19-136/141
Sequence Identity: 46% (54 aa)

GHRMGLVIDLTKTSRYYDKRELLKCGIGHHKITCEGYGaAPNAEQVKEFQTLCVNFF--KDHPDDIIGVHCTHGFNRTGFLIVSYLIDVECWDLESAVAT
....|||||||.| |||.|.|| . |. ..|..| |    |. |.||.|..   .|   ... | .|||||||| ||||.||  ||||||.. | |. .|
nkklGLvidltntdryykkkeltdegvkykklncpGhe-vpekedvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyspedaiea

FSMARPPGIYKEHYLHELA
. ||   . .|.||..|  
feearGhslerenyledLk

Phosphatase aque_RNGTT-B.AA Family.DSP.PD 61-174 25 3.5e-17 52.4 In-house 132-240 (387) Show / Hide
Range on Protein: 61-174
Range on HMM: 132-240/387
Sequence Identity: 25% (30 aa)

RMGLVIDLT--KTSRYYdkrellKCGIGHHKITCEGYgAAPNAEQVkeFQTlCVNFFKDH--PDDIIGVHCTHGFNRTGFLIVSYLIDVECWDLESAVAT
..  ...||  |.. ..      . || ...| .. .  ||. |..  |.  ...| ...  .   . |||..| .|.| ||. ||.  | . |||.. .
gvtkivnltddkpqftk------elgikylripidDh-napplenl--fek-aidfieegndskgvVlVHCkaGkgRsgtliiaYlmksegltleealdw

FSMARPpGIYK--EHYLHEL
. .|| |. .  ...|..| 
vrskRp-gvitpnqgflkql

Phosphatase aque_RNGTT-B.AA Subfamily.CDC14.PD 64-165 26 3e-11 33.2 In-house 150-243 (258) Show / Hide
Range on Protein: 64-165
Range on HMM: 150-243/258
Sequence Identity: 26% (27 aa)

LVIDLTKTsrYYDKRELLKCGIGHHKITCEGyGAAPNAEQVKEFQTLCVNFfkdhpDDIIGVHCTHGFNRTGFLIVSYLIDVECWDLESAVATFSMARPP
.. | |    ||...  . |. |. .  .  |. |. . .|.| ... .      .  | |||  |  ||| || .|||       . ..| . .|||  
tivrLnkk--lYdakkftdaGfahlDlffiD-GtvPsdailkkfleiteka-----eGaiavhCkaGLGrtgtligcylikhyrftaaetiawlriarPG

GI
. 
sv

Phosphatase aque_RNGTT-B.AA Subfamily.DSP23.PD 66-165 25 9.5e-11 31.6 In-house 18-111 (128) Show / Hide
Range on Protein: 66-165
Range on HMM: 18-111/128
Sequence Identity: 25% (24 aa)

IDLTKTSRYYDKRellKCGIGHHKITCEGYgAAPNAEQVKEFQTLCVNFfkDHPDDIIGVHCTHGFNRTGFLIVSYLIDVECWDLESAVATFSMARPPGI
..||. .. | .      ... ..|  . .   |  |||...  .. .   .. .. .||||  |. ||| |.  ||.  |    . |.||.  |     
vslttegapysea---apsltlrridipdf-cPPaleqvarlvriveea--ekkeeavgvhcalGlGrtGtllacylvkeeglaaddaiaevrkrrkGsi





Phosphatase aque_RNGTT-B.AA Subfamily.PRL.PD 74-154 32 2e-09 27.1 In-house 36-114 (140) Show / Hide
Range on Protein: 74-154
Range on HMM: 36-114/140
Sequence Identity: 32% (26 aa)

YYDKRELLKCGIGHHKITCEGyGAAPNAEQVKEFQTLCVNFFKDHPDDIIGVHCTHGFNRTGFLIVSYLIDVEcWDLESAV
||  .| . ||  . .. .  ||.|  | |.|. .|. . ||..|. ...|||  |. |.  |.   ||.    . | || 
sydaeklkeegievldlafdd-GavPpkevvdeWlellkekfkeepkstvavhcvaGlGraPvlvalalieaG-mkyedav

Phosphatase aque_RNGTT-B.AA Subfamily.PTPDC1.PD 75-168 31 9.1e-09 24.8 In-house 125-214 (229) Show / Hide
Range on Protein: 75-168
Range on HMM: 125-214/229
Sequence Identity: 31% (28 aa)

YDKRELLKCGIGHHKITCEGYGAAPNAEQVkEFQTLcVNFFKdhPDDIIGVHCTHGFNRTGFLIVSYLIDVECWDLESAVATFSMARPPGIYKE
||. ||.. || ..... . ||.|.  . . .   . |.|     .  |.|||  |  ||| || .||. ..  . | |. .    |||.    
YdpeelmrqgiyfynfglkDygvasleriL-divkv-vdfal--eegkiavHCHAGlGRtGvliacylvyakrltaeeaiklvrskrpksiqtr

Phosphatase aque_RNGTT-B.AA Subfamily.PTEN.PD 98-161 26 3.1e-08 23.0 In-house 72-136 (305) Show / Hide
Range on Protein: 98-161
Range on HMM: 72-136/305
Sequence Identity: 26% (17 aa)

APNAEQVKEFQTLCVNFFKDHPDDIIGVHCTHGFNRTGFLIVSYLIDVECWD-LESAVATFSMAR
.|. | ..|.     .. |   . .. |||  |  ||| .|..||.     .  . |.| .. .|
pptleLleeivedvdkwLkedksnVvavHCkaGkGRtGvmicayLlksgikksadealaiydekR

Phosphatase aque_RNGTT-B.AA Subfamily.PTPMT1.PD 77-163 23 3.5e-07 19.9 In-house 45-129 (146) Show / Hide
Range on Protein: 77-163
Range on HMM: 45-129/146
Sequence Identity: 23% (20 aa)

KRELLKCGIGHHKITCEGYGAAPNAEQVKEFQTLCVNFFKDhpDDIIGVHCTHGFNRTGFLIVSYLIDVECWDLESAVATFSMARPP
..|  | |. . ...   .. ||. |...|  ..  .. ..   . . |||  |  | . |. .||.  . .  |.|| ..   || 
teewkklGveqlqlatvDfteapslekleegvefiekvask--gssvYvHCkAGrtRsatlvacylmkkkklspeeavkflkkkRpq

Phosphatase aque_RNGTT-B.AA Subfamily.DSP12.PD 111-163 24 9.4e-07 18.7 In-house 70-124 (143) Show / Hide
Range on Protein: 111-163
Range on HMM: 70-124/143
Sequence Identity: 24% (13 aa)

CVNFFKDHP--DDIIGVHCTHGFNRTGFLIVSYLIDVECWDLESAVATFSMARPP
.|.| ..    .. . |||. |  |   ... ||.  | ..||.|. . . ... 
avrFieeglekegavlvHClagvSRSvtiviAYlmkkeklslekAlklvkekkke

Phosphatase aque_RNGTT-B.AA Subfamily.TPIP.PD 99-148 24 1.7e-06 17.5 In-house 16-65 (245) Show / Hide
Range on Protein: 99-148
Range on HMM: 16-65/245
Sequence Identity: 24% (12 aa)

PNAEQVKEFQTLCVNFFKDHPDDIIGVHCTHGFNRTGFLIVSYLIDVECW
|. |..  |     ....  ..... .||  | .||| .. ..||  | .
PtleelvvftkevkewlakdlenvvaihckGGkgrtGtivcalliaseif

Phosphatase aque_RNGTT-B.AA Subfamily.DSP19.PD 107-163 25 3.9e-06 16.5 In-house 64-122 (139) Show / Hide
Range on Protein: 107-163
Range on HMM: 64-122/139
Sequence Identity: 25% (15 aa)

FQTLCVNFFKDHPD--DIIGVHCTHGFNRTGFLIVSYLIDVECWDLESAVATFSMARPP
.   ...| ..  .   .. |||  |  |.  ....||.  |  .||.|. .   |||.
ylkealdFieearskdgrvlvHCnAGvSRsasvviaylmkdeelslekalekvrearpc

Phosphatase aque_RNGTT-B.AA DSPc 123-174 22 5e-06 22.81 Pfam 88-145 (151) Show / Hide
Range on Protein: 123-174
Range on HMM: 88-145/151
Sequence Identity: 22% (13 aa)

IGVHCTHGFNRTGFLIVSYLIDVECWDLESAVATF-----SMARPPGIYKE-HYLHEL
. |||..| .|.. |.. ||..  ..... | . .      . | |.|.   .... |
VLVHCQAGISRSACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQL

MRNA_cap_C aque_RNGTT-B.AA mRNA_cap_C 464-565 33 1.2e-31 113.82 Pfam 1-138 (138) Show / Hide
Range on Protein: 464-565
Range on HMM: 1-138/138
Sequence Identity: 33% (46 aa)

ELNTVDFRLNIISEQ---KVGML---QEKKAQL-LVG---------SGRHTVLF-------SYLDL------HVNKEAKAHNNKIIECSF-VDK----K-
|.|||||.|... |.   . |||   |...  | ..           |.. . |       . ...       . .. |  ||||.||.. ||.      
EMNTVDFMLKMCFECIGGEDGMLDRFQQWRGYLDYMEMPNFQKGRWWGGYNCPFFCKMYVFNKMRIFDIEWEKWTNDEKPYNNKIVECTWLVDNKQKGRP

-WKFLRVRTDKSFPNSFETARSVCMSISQPVTKQWLLE
 |.|.|.|||||.||.. |||.|| ||. .|||  |.|
EWVFMRFRTDKSNPNHINTARKVCYSIEDNVTKEYLFE

Sequence
Name Sequence Type Origin Length Description Download
aque_RNGTT-B.AA Protein None 605 None Fasta, JSON
aque_RNGTT-B.NA RNA None 1815 None Fasta, JSON
aque_RNGTT-B.AA.PD_123-174 Protein Phosphatase Domain None 52 None Fasta, JSON