Aque_g32274.t1
Species: A.queenslandica
Alias: Aque_g32274.t1
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Myotubularin
Subfamily: C2-MTMR1
Protein domain

Protein domains of Aque_g32274.t1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C2 Aque_g32274.t1.AA C2 9-120 15 1.3e-07 32.51 SMART 1-92 (92) Show / Hide
Range on Protein: 9-120
Range on HMM: 1-92/92
Sequence Identity: 15% (20 aa)

KLRVEVLKARDLAPADTNGKSDPYCIVSLGQKVVQTSVQPQTL---FPEWMQ---SMAFFSSDLEPFALIQGGITEKIEIGFQRLIILSVGDMKGNKAIS
.|.| ...||.|         |||..|.      .|.| . ||    |.| .   .. |  ..                    . ....| |    . | 
TLTVHIIEARNLP--------DPYVKVY------KTKVVKNTLSGFNPVWNEWMETFYFDVHP--------------------Q-LRFEVWDH---DFIG

TTNLS--------------PMTTTTTQDSSMW
.....                .    . . .|
HCCIPPNNPHWHQWDGCIHLSDIL-GYRH-WW

Aque_g32274.t1.AA Myotub-related 421-507 29 1.3e-21 82.9 Pfam 31-121 (121) Show / Hide
Range on Protein: 421-507
Range on HMM: 31-121/121
Sequence Identity: 29% (27 aa)

RGRVPSLVWMDKVNGTFLLRSAQPLPGLSDKHSTEDETLLKYAIT-CY---EGEGLMIFDARSSSAATGNRIMGKGTEDVSRYYRCKLTHL
.||.| |.|. . ||. ..|..||| |.... . ||| |..   . .    ..  ..|.|||....|  ||..|.|.|. . |  ......
WGRFPVLCWRHQENGAVICRCSQPLVGWWGWRCKEDEKLVQAIMKANADMIQSRKMYIVDARPYTNAMANRAKGGGYENEEHYPNWEFVFM

C2 Aque_g32274.t1.AA C2 10-73 36 1.4e-17 62.45 Pfam 1-71 (90) Show / Hide
Range on Protein: 10-73
Range on HMM: 1-71/90
Sequence Identity: 36% (26 aa)

LRVEVLKARDLAPAD--TNGKSDPYCIVSLGQ-----KVVQTSVQPQTLFPEWMQSMAFFSSDLEPFAL-IQ
||| |..||.|.| |   |||||||. |.||.     .. .|.| . || |.| ... |   ......  ..
LRVHVIEARNLPPMDWDKNGKSDPYVKVYLGGDPKDTQKYKTKVIKNTLNPVWNETFTFD-VPPPDLQHTLR

Phosphatase Aque_g32274.t1.AA Family.Myotubularin.PD 530-664 57 9.7e-61 192.2 In-house 3-140 (141) Show / Hide
Range on Protein: 530-664
Range on HMM: 3-140/141
Sequence Identity: 57% (80 aa)

SSTRWYSSLESTQWIEYISLILKGSYLIARLIKIHSGSALIHCSDGWDRTAQLTSLTQIIIDSYYRTIDGFLTLIAKEWLSYGHKFKERLGHPLN---PN
....|.|.||||.|.|.|.|.||..  |.. .. .. | |.|||||||||||||||.|...|.|||||.||  || |||||.||||.|||||  .    .
eekkwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdksesee

ERSPIFLQFLDCVHQLMNQYPHAFQFNLSFLLTIAEHL
||||.||||.|||.||..|.|.||.|| |||..|..||
ersPvflqfidcvyqltkqfptafefnesflikildhl

Phosphatase Aque_g32274.t1.AA Subfamily.C2-MTMR1.PD 530-664 55 9.8e-61 192.4 In-house 2-136 (137) Show / Hide
Range on Protein: 530-664
Range on HMM: 2-136/137
Sequence Identity: 55% (74 aa)

SSTRWYSSLESTQWIEYISLILKGSYLIARLIKIHSGSALIHCSDGWDRTAQLTSLTQIIIDSYYRTIDGFLTLIAKEWLSYGHKFKERLGHPLNPNERS
|  .|.| ||||||. ||. .||..  ||| ..  . |||.|||||||||.||..|.|...| |||||||.  || ||||..||||.||||..  . |||
sdvqwlsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlggadsvsers

PIFLQFLDCVHQLMNQYPHAFQFNLSFLLTIAEHL
|||||||||..|.  |.| ||...  .|| .|.. 
piflqfldclyqvtkqfpsafeytarlllkladys

Phosphatase Aque_g32274.t1.AA Subfamily.MTMR1.PD 528-664 55 6e-56 177.0 In-house 9-148 (149) Show / Hide
Range on Protein: 528-664
Range on HMM: 9-148/149
Sequence Identity: 55% (78 aa)

STSSTRWYSSLESTQWIEYISLILKGSYLIARLIKIHSGSALIHCSDGWDRTAQLTSLTQIIIDSYYRTIDGFLTLIAKEWLSYGHKFKERLGHPLN---
|.  ..|.|.||.|.|.|.| |||.|.  ||  .. .. | ..|||||||||||||||. ...||||||| || .|| |||||.||||.||.||  .   
sideskwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaerighgdknha

PNERSPIFLQFLDCVHQLMNQYPHAFQFNLSFLLTIAEHL
 ..|||.||||.||| |...|.|.||.|| .||.|| .||
dadrspvflqfidcvwqvtrqfptafefneeflitildhl

Phosphatase Aque_g32274.t1.AA Subfamily.MTMR3.PD 534-663 46 6.2e-51 160.5 In-house 1-133 (135) Show / Hide
Range on Protein: 534-663
Range on HMM: 1-133/135
Sequence Identity: 46% (60 aa)

WYSSLESTQWIEYISLILKGSYLIARLIKIHSGSALIHCSDGWDRTAQLTSLTQIIIDSYYRTIDGFLTLIAKEWLSYGHKFKERLGHPLN---PNERSP
..|.||.|.|.. .| .|| .  ... .. ..   |.|||||||||.|...|.....| ||||..||  |. .|||..|||| .| ||  .|||.|.|||
flsalektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercp

IFLQFLDCVHQLMNQYPHAFQFNLSFLLTIAEH
.||||||| .|.| .|.|| .||. ...|    
vflqwldcvhqlkkqfptsfefneaflvklvqh

FYVE Aque_g32274.t1.AA FYVE 779-803 30 4e-06 23.37 Pfam 1-26 (71) Show / Hide
Range on Protein: 779-803
Range on HMM: 1-26/71
Sequence Identity: 30% (8 aa)

IVWMSDDKTKDCLSCHKKFSIL-RRK
 .|. |.  . | .|.|.|... ||.
PHWQPDSEVTHCMICQKPFTFFGRRR

Phosphatase Aque_g32274.t1.AA PTPc_motif 495-665 8 6e-06 18.55 SMART 1-92 (92) Show / Hide
Range on Protein: 495-665
Range on HMM: 1-92/92
Sequence Identity: 8% (15 aa)

DVSRYYRCKLTHL-----DIPNIHAVRESYEGLKQLALSTSSTRWYSSLESTQWIEYISLILKGSYLIARLIKIHSGSALIHCSDGWDRTAQLTSLTQII
 | .|.     .       .|  ... |  . ...                                          . ..|||.|..||... ..  ..
TVHHYHYTNWPDHVEKDSGVPE-DSILEFIRHVRK------------------------------------------PIVVHCSAGCGRTGTFCAIDMMM

IDSYYRTIDGFLTLIAKEWLSYGHKFKERLGHPLNPNERSPIFLQFLDCVHQLMNQYPHAFQFNLSFLLTIAEHLN
 .                                         . ....|.....| |...| .  ..  .. .|.
QQ-----------------------------------------VDIFQTVKEMRKQRPGMVQTEEQYIFCYRCILE

Sequence
Name Sequence Type Origin Length Description Download
Aque_g32274.t1.AA Protein None 822 None Fasta, JSON
Aque_g32274.t1.NA RNA None 2466 None Fasta, JSON