Gene Aque_g20958.t1
Aque_g20958.t1
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Aque_g20958.t1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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UDENN | Aque_g20958.t1.AA | uDENN | 2-101 | 22 | 2.1e-11 | 43.18 | Pfam | 1-95 (95) | Show / Hide |
Range on Protein: 2-101 Range on HMM: 1-95/95 Sequence Identity: 22% (24 aa) SQRLVEYLVIVGPGEVISTPEIPSQNVLDDMVTKVDVKPRVCQRFPTENR----ASGSLPAGIELFCRSQGWCLTSHP---PPPSFNNFILTSELGSHFY .|||..|.|..| . . ... ||.. ...| . . .| ....|| .|| . . . ..|.| |.|| | || .| MQRLFDYFVVCGYDKD------------HMHPLGRSYKPKILDQYPPKDHMQMFWDPPFPDAVPMFCFPDGWDWVTWRDRHYDPQFFSFVLTDEDGSRWY CCSLNFH .. ..| GFCRTFY |
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DENN | Aque_g20958.t1.AA | DENN | 184-384 | 20 | 1e-21 | 79.39 | SMART | 1-204 (204) | Show / Hide |
Range on Protein: 184-384 Range on HMM: 1-204/204 Sequence Identity: 20% (46 aa) SEPLSL-CLVAKYPIYDALQVLLKSIYIHHV--MGDTLDKFSSSQLPVSPHSTTMEELISELLIDLRFPLPGKPLVK------RSFG-PLKEL--TLVPL | .. |.. .| ... . .|...| ... . |. . .|. .. .| |||..| .|. |... .. . WTPKCIHCIISHHPWFNWFRKWLNELYRYWQSDHNQHLFHHE--------------FMIYLCHYPVPLPPPGKSIVFMSIVSYFQFHPPGNYYQPIEFCR NIMETIPYTS--DNTYRLLKAIGVHGLLQLFSLILVDGKLLFISSSITAITSAIISVVSLMYPIGIDHFSCLLI---PSGFVEYLHCITPFLMGLHRSLL .| . . . |....|| ..|||. || . .|.||... ..... ..|.|.|| . ....| | ..||.. .|..||.|.|.. PDDNRLPHIDENWDLHELFECLGVENIMQLFCCILLERRIIFHSSNYQMLSMCCHAFVALLYPF---QWQHIYIPILPASMLDYLCAPMPYIMGCHSSYF VELDEEPLD---VTLVDLDSG | ..||.. | .||.|.. EEVKPEPDEEDDVVVVDIDTN |
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UDENN | Aque_g20958.t1.AA | uDENN | 2-101 | 19 | 1.6e-09 | 38.84 | SMART | 1-114 (114) | Show / Hide |
Range on Protein: 2-101 Range on HMM: 1-114/114 Sequence Identity: 19% (24 aa) SQRLVEYLVIVGPGEVI------------------STPEIPSQNVLDDMVTKVDVKPRVCQRFPTENRASGSLPAGIELFCRSQGWCL-----TSHPPPP ..||..|....| . . .. . . ... || . ...| . . .| .|..|| || . . .|.| PHRLFDYFCVCGCPKDPGWWPDMHYACYQWEAPGRT-GC-F-C------PLQRSYKPEILYQYPEKDWWDFPFPDMIPMFCFPMGWDWCTWPRKTDRPDP SFNNFILTSELGSHFYCCSLNFH .| |.||.| || .|. ..| QFFTFVLTDEDGSRRYGFCRRFY |
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DENN | Aque_g20958.t1.AA | DENN | 184-384 | 24 | 9.1e-20 | 69.54 | Pfam | 1-207 (207) | Show / Hide |
Range on Protein: 184-384 Range on HMM: 1-207/207 Sequence Identity: 24% (52 aa) SEPLSLCLVAKYPIYDAL-QVLLKSIYIHHVMGDTLDKFSSSQLPVSPHSTTMEELISELLIDLRFPLPGKPLVKRS---FGPLKELTLVPLNIMETI-P | ..|.. ..| .... |. ||.... ..... .|| | . . .| .|..|. . || ||...| | .| ... ... | WIPKCYCIISRWPWFNTFWRKWLDCIYRRYTSCPHPRIPPSS--PRVGMWNPIERYIQNLCYEVPFPPPGRTQVLFSFIPLGVYEPILFQRPSPDSELHP YTSDNTYR-LLKAIGVHGLLQLFSLILVDGKLLFISSSITAITSAIISVVSLMYPIGIDHFSCLLIP---SGFVEYLHCITPFLMGLHRSLLV--ELDEE ... .. |... |. .|.|| ..| . .|.||.. |... .||.|.|| . .. || ..||.. .||.||.|.... .|... VWEHIDFHPLFRCLGPENCLHLFCCVLTEHRIIFHSSHYAMLTLCCHAVVALLYPF---QWQHIYIPICPARLLDYLCAPCPFIMGVHSRYFDSKLLYDP PLDVTLVDLDSG |.||..|||| . PDDVVCVDLDTN |
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SBF2 | Aque_g20958.t1.AA | SBF2 | 628-766 | 31 | 3e-18 | 61.91 | Pfam | 45-188 (233) | Show / Hide |
Range on Protein: 628-766 Range on HMM: 45-188/233 Sequence Identity: 31% (46 aa) FSSRILEARKYFPSVTMSLRQRVTTPIFIPELVNKLMRNGA-YLSPDQFEVMVRLVNCAL-----VDEK-IAMQILPLTSVFYQEIQPGVNQYLYSCIQS | ..||||.| || | .|..|.. . || | . | .|| ||. |||| .|| .| ..|||...|. |||.|. |.|.| FDNKILEAKKMFPAVLRALKGRAARICLCRELNLHCQQNRHFVLDHQQFDMVVRMMNCALQDCCSMDEYGVAAALLPLSTAFCRKLCPGVHQFAYTCVQD HRLWQSTRFWCHSLYSAIQAELVRLYADVPFKKEKPKSIEEEDEDL | | . .|| . |. |. . || .....|. ....... HPVWKNQQFWEACFYQDVQNHIRELYL--NMHHDEQKTWSDWCHKQ |
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GRAM | Aque_g20958.t1.AA | GRAM | 996-1044 | 19 | 6e-06 | 24.29 | Pfam | 31-78 (78) | Show / Hide |
Range on Protein: 996-1044 Range on HMM: 31-78/78 Sequence Identity: 19% (10 aa) R---LVPAHGHVYLTSYRIVFLGSPWDPEVDPNVLVTRSMPISSIYRMKELS | ..|..|..|.|.... | ... ..|. .... .|...| |.. . RPFTKIPVQGRMYITNHHVCFYSDKFGWET----YYKMVIPWNDITRVEKMQ |
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Myotub-related | Aque_g20958.t1.AA | Myotub-related | 1193-1244 | 32 | 1.9e-13 | 53.2 | Pfam | 1-52 (121) | Show / Hide |
Range on Protein: 1193-1244 Range on HMM: 1-52/121 Sequence Identity: 32% (17 aa) FTLCETYPAVWVVPDKFSDESITRILPHFQQGRVPIVTWKHPRTKAILLRSA ...|.|||| .||| ||. . . ...||.| ..| |....| ..|.. YEICPTYPAKLVVPKSISDDELKKVAKFRSWGRFPVLCWRHQENGAVICRCS |
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Phosphatase | Aque_g20958.t1.AA | Subfamily.MTMR1.PD | 1606-1722 | 44 | 4.1e-34 | 105.8 | In-house | 9-127 (149) | Show / Hide |
Range on Protein: 1606-1722 Range on HMM: 9-127/149 Sequence Identity: 44% (53 aa) TTHQSKFYSLVEDSDWINQLSSLLQLSGAVADLMDAQGSSVLVGLEDGWDATAQVVSLAQLLMDPYYRTMKGFCALIEKEWLALGHPFTDRSCQI--QSS ....||..| .|.. |.... ..|. . .|| .... .||.| |||| |||. ||| ||.|.||||.||| |||||||..|| |..| . . sideskwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaerighgdknha SGAISPVFLQFLDCVHQEM . |||||||.||| | . dadrspvflqfidcvwqvt |
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Phosphatase | Aque_g20958.t1.AA | Family.Myotubularin.PD | 1608-1722 | 46 | 7.6e-41 | 127.4 | In-house | 3-119 (141) | Show / Hide |
Range on Protein: 1608-1722 Range on HMM: 3-119/141 Sequence Identity: 46% (54 aa) HQSKFYSLVEDSDWINQLSSLLQLSGAVADLMDAQGSSVLVGLEDGWDATAQVVSLAQLLMDPYYRTMKGFCALIEKEWLALGHPFTDRSCQIQSS--SG ...|..| .|.. |......||. . ... .. ...|||| |||| |||..||||||.||||||..|| |||||||..|||..| . ..| . eekkwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdksesee AISPVFLQFLDCVHQEM |||||||.|||.| . ersPvflqfidcvyqlt |
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Phosphatase | Aque_g20958.t1.AA | Subfamily.C2-MTMR1.PD | 1610-1734 | 42 | 5.4e-37 | 115.2 | In-house | 4-128 (137) | Show / Hide |
Range on Protein: 1610-1734 Range on HMM: 4-128/137 Sequence Identity: 42% (53 aa) SKFYSLVEDSDWINQLSSLLQLSGAVADLMDAQGSSVLVGLEDGWDATAQVVSLAQLLMDPYYRTMKGFCALIEKEWLALGHPFTDRSCQIQSSSgAISP ...| .|...|. ....|. . |.| .. . | || |||| |.|.|.|||||.||||||..|. ||||||||.|| | .| . .|.| ||. vqwlsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlggadsvs-ersp VFLQFLDCVHQEML-RPHSYQANLDI |||||||..| | ... . . iflqfldclyqvtkqfpsafeytarl |
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Phosphatase | Aque_g20958.t1.AA | Subfamily.MTMR3.PD | 1612-1721 | 50 | 1.2e-36 | 114.0 | In-house | 1-112 (135) | Show / Hide |
Range on Protein: 1612-1721 Range on HMM: 1-112/135 Sequence Identity: 50% (55 aa) FYSLVEDSDWINQLSSLLQLSGAVADLMDAQGSSVLVGLEDGWDATAQVVSLAQLLMDPYYRTMKGFCALIEKEWLALGHPFTDRSCQIQSS--SGAISP |.| .|.. |...|| ||. . |.. .| .| ||| |||| |.|.|.||.||.||||||..|| .|.|.||| .|| |.||. .. | . .|| flsalektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercp VFLQFLDCVHQE |||.|||||| vflqwldcvhql |
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C1 | Aque_g20958.t1.AA | C1 | 1907-1955 | 19 | 9e-06 | 26.41 | SMART | 1-61 (61) | Show / Hide |
Range on Protein: 1907-1955 Range on HMM: 1-61/61 Sequence Identity: 19% (12 aa) HSFQSFKVGSTQYECSYCHHIIRDKD-------AFKCKNCSGTCHNYCKRHMPS-------NC |... .. . | |..|.. |. . ...| .| .||. |....|. .| HHWHWWRF-KPTY-CCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC |
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PH | Aque_g20958.t1.AA | PH | 2001-2110 | 20 | 5.3e-15 | 57.09 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 2001-2110 Range on HMM: 1-82/82 Sequence Identity: 20% (23 aa) IELEGFLFKKGGVVKNWKERYFVLNLEKGNLAYYESDKRGAKLCGTIALEAISKVEECDPIVVPSTILKSGQVGYFFKLTTNRRVFTLMTFRTSTRSQWI ...||.| ||. .||.|.||| . | ||... |. |.| |. . .|.| . |.... |.... . ... .|. VIKEGWLYKKS--K-RWKKRWFVLFN--DCLYYYKDK----KPKGSIPLSDC-TVRE-P----------------CFEIHH-DRTYYFQCESEEEMQEWM RKLTDSSKRF . . . ... QAIQKAIHNN |
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PH | Aque_g20958.t1.AA | PH | 2001-2108 | 23 | 2.8e-14 | 54.16 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 2001-2108 Range on HMM: 1-92/92 Sequence Identity: 23% (26 aa) IELEGFLFKKGGVVKNWKERYFVLNLEKGNLAYYESDKRGAKLCGTIALEAISKVEECDPIVVPSTILKSGQVGYFFKLTTNRR-VFTLMTFRTSTRSQW ...||.|.||| |.||.|.||| ..| ||..|| ... |.| |. . .|..... . |...| | .... . . .| VIKEGWLHKKG-KRKSWKKRWFVLFN--NCLYYYKDDK--YRPKGSIPLSDC-QVTKVPDN----------KRPHCFQIRT-DRRTYYFQAESEEEMNDW IRKLTDSSK .. . . .. MQAIQSACR |
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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Aque_g20958.t1.AA | Protein | None | 2113 | None | Fasta, JSON |
Aque_g20958.t1.NA | RNA | None | 6339 | None | Fasta, JSON |