Aque_g20958.t1
Species: A.queenslandica
Alias: Aque_g20958.t1
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Myotubularin
Subfamily: MTMR5
Protein domain

Protein domains of Aque_g20958.t1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
UDENN Aque_g20958.t1.AA uDENN 2-101 22 2.1e-11 43.18 Pfam 1-95 (95) Show / Hide
Range on Protein: 2-101
Range on HMM: 1-95/95
Sequence Identity: 22% (24 aa)

SQRLVEYLVIVGPGEVISTPEIPSQNVLDDMVTKVDVKPRVCQRFPTENR----ASGSLPAGIELFCRSQGWCLTSHP---PPPSFNNFILTSELGSHFY
.|||..|.|..| .              .    ... ||.. ...|  .       . .| ....||  .|| . . .   ..|.|  |.|| | || .|
MQRLFDYFVVCGYDKD------------HMHPLGRSYKPKILDQYPPKDHMQMFWDPPFPDAVPMFCFPDGWDWVTWRDRHYDPQFFSFVLTDEDGSRWY

CCSLNFH
.. ..| 
GFCRTFY

DENN Aque_g20958.t1.AA DENN 184-384 20 1e-21 79.39 SMART 1-204 (204) Show / Hide
Range on Protein: 184-384
Range on HMM: 1-204/204
Sequence Identity: 20% (46 aa)

SEPLSL-CLVAKYPIYDALQVLLKSIYIHHV--MGDTLDKFSSSQLPVSPHSTTMEELISELLIDLRFPLPGKPLVK------RSFG-PLKEL--TLVPL
  | .. |..  .| ... . .|...| ...   .  |.  .               .|. ..    .| |||..|        .|. |...   ..  .
WTPKCIHCIISHHPWFNWFRKWLNELYRYWQSDHNQHLFHHE--------------FMIYLCHYPVPLPPPGKSIVFMSIVSYFQFHPPGNYYQPIEFCR

NIMETIPYTS--DNTYRLLKAIGVHGLLQLFSLILVDGKLLFISSSITAITSAIISVVSLMYPIGIDHFSCLLI---PSGFVEYLHCITPFLMGLHRSLL
     .| .    . . |....||  ..|||. ||   . .|.||... ..... ..|.|.||    . ....|   |   ..||.. .|..||.|.|..
PDDNRLPHIDENWDLHELFECLGVENIMQLFCCILLERRIIFHSSNYQMLSMCCHAFVALLYPF---QWQHIYIPILPASMLDYLCAPMPYIMGCHSSYF

VELDEEPLD---VTLVDLDSG
 | ..||..   | .||.|..
EEVKPEPDEEDDVVVVDIDTN

UDENN Aque_g20958.t1.AA uDENN 2-101 19 1.6e-09 38.84 SMART 1-114 (114) Show / Hide
Range on Protein: 2-101
Range on HMM: 1-114/114
Sequence Identity: 19% (24 aa)

SQRLVEYLVIVGPGEVI------------------STPEIPSQNVLDDMVTKVDVKPRVCQRFPTENRASGSLPAGIELFCRSQGWCL-----TSHPPPP
..||..|....| .  .                    .. . .        ... || . ...| . .    .| .|..||   || .      . .|.|
PHRLFDYFCVCGCPKDPGWWPDMHYACYQWEAPGRT-GC-F-C------PLQRSYKPEILYQYPEKDWWDFPFPDMIPMFCFPMGWDWCTWPRKTDRPDP

SFNNFILTSELGSHFYCCSLNFH
.|  |.||.| || .|.  ..| 
QFFTFVLTDEDGSRRYGFCRRFY

DENN Aque_g20958.t1.AA DENN 184-384 24 9.1e-20 69.54 Pfam 1-207 (207) Show / Hide
Range on Protein: 184-384
Range on HMM: 1-207/207
Sequence Identity: 24% (52 aa)

SEPLSLCLVAKYPIYDAL-QVLLKSIYIHHVMGDTLDKFSSSQLPVSPHSTTMEELISELLIDLRFPLPGKPLVKRS---FGPLKELTLVPLNIMETI-P
  | ..|.. ..| ....    |. ||.... .....  .||  | .  .  .| .|..|. .  || ||...|  |   .|    ...      ... |
WIPKCYCIISRWPWFNTFWRKWLDCIYRRYTSCPHPRIPPSS--PRVGMWNPIERYIQNLCYEVPFPPPGRTQVLFSFIPLGVYEPILFQRPSPDSELHP

YTSDNTYR-LLKAIGVHGLLQLFSLILVDGKLLFISSSITAITSAIISVVSLMYPIGIDHFSCLLIP---SGFVEYLHCITPFLMGLHRSLLV--ELDEE
 ...  .. |... |.  .|.|| ..|   . .|.||..   |... .||.|.||    . ..  ||      ..||.. .||.||.|....   .|...
VWEHIDFHPLFRCLGPENCLHLFCCVLTEHRIIFHSSHYAMLTLCCHAVVALLYPF---QWQHIYIPICPARLLDYLCAPCPFIMGVHSRYFDSKLLYDP

PLDVTLVDLDSG
|.||..|||| .
PDDVVCVDLDTN

SBF2 Aque_g20958.t1.AA SBF2 628-766 31 3e-18 61.91 Pfam 45-188 (233) Show / Hide
Range on Protein: 628-766
Range on HMM: 45-188/233
Sequence Identity: 31% (46 aa)

FSSRILEARKYFPSVTMSLRQRVTTPIFIPELVNKLMRNGA-YLSPDQFEVMVRLVNCAL-----VDEK-IAMQILPLTSVFYQEIQPGVNQYLYSCIQS
| ..||||.| || |  .|..|..  .   ||      | .  |  .||   ||. ||||     .||  .| ..|||...|.    |||.|. |.|.| 
FDNKILEAKKMFPAVLRALKGRAARICLCRELNLHCQQNRHFVLDHQQFDMVVRMMNCALQDCCSMDEYGVAAALLPLSTAFCRKLCPGVHQFAYTCVQD

HRLWQSTRFWCHSLYSAIQAELVRLYADVPFKKEKPKSIEEEDEDL
|  | . .||  . |.  |. .  ||     .....|. .......
HPVWKNQQFWEACFYQDVQNHIRELYL--NMHHDEQKTWSDWCHKQ

GRAM Aque_g20958.t1.AA GRAM 996-1044 19 6e-06 24.29 Pfam 31-78 (78) Show / Hide
Range on Protein: 996-1044
Range on HMM: 31-78/78
Sequence Identity: 19% (10 aa)

R---LVPAHGHVYLTSYRIVFLGSPWDPEVDPNVLVTRSMPISSIYRMKELS
|   ..|..|..|.|.... | ... ..|.    .... .|...| |..  .
RPFTKIPVQGRMYITNHHVCFYSDKFGWET----YYKMVIPWNDITRVEKMQ

Aque_g20958.t1.AA Myotub-related 1193-1244 32 1.9e-13 53.2 Pfam 1-52 (121) Show / Hide
Range on Protein: 1193-1244
Range on HMM: 1-52/121
Sequence Identity: 32% (17 aa)

FTLCETYPAVWVVPDKFSDESITRILPHFQQGRVPIVTWKHPRTKAILLRSA
...|.|||| .|||   ||. . .    ...||.| ..| |....| ..|..
YEICPTYPAKLVVPKSISDDELKKVAKFRSWGRFPVLCWRHQENGAVICRCS

Phosphatase Aque_g20958.t1.AA Subfamily.MTMR1.PD 1606-1722 44 4.1e-34 105.8 In-house 9-127 (149) Show / Hide
Range on Protein: 1606-1722
Range on HMM: 9-127/149
Sequence Identity: 44% (53 aa)

TTHQSKFYSLVEDSDWINQLSSLLQLSGAVADLMDAQGSSVLVGLEDGWDATAQVVSLAQLLMDPYYRTMKGFCALIEKEWLALGHPFTDRSCQI--QSS
....||..| .|.. |.... ..|. .  .|| .... .||.|   |||| |||. ||| ||.|.||||.|||  |||||||..|| |..|      . .
sideskwlsaleetkwlehiklilagavriadkvesektsvvvhcsdgwdrtaqltslamllldsyyrtikgfevliekewlsfghkfaerighgdknha

SGAISPVFLQFLDCVHQEM
 .  |||||||.||| | .
dadrspvflqfidcvwqvt

Phosphatase Aque_g20958.t1.AA Family.Myotubularin.PD 1608-1722 46 7.6e-41 127.4 In-house 3-119 (141) Show / Hide
Range on Protein: 1608-1722
Range on HMM: 3-119/141
Sequence Identity: 46% (54 aa)

HQSKFYSLVEDSDWINQLSSLLQLSGAVADLMDAQGSSVLVGLEDGWDATAQVVSLAQLLMDPYYRTMKGFCALIEKEWLALGHPFTDRSCQIQSS--SG
...|..| .|.. |......||. .  ... .. ...||||   |||| |||..||||||.||||||..||  |||||||..|||..|  . ..|  .  
eekkwlselestkWlehiklllkaavkivekvekektsvlvhcsdGWdrtaqltslaqllldpyyrtieGfevliekeWlsfGhkfaerlghgdksesee

AISPVFLQFLDCVHQEM
 |||||||.|||.| . 
ersPvflqfidcvyqlt

Phosphatase Aque_g20958.t1.AA Subfamily.C2-MTMR1.PD 1610-1734 42 5.4e-37 115.2 In-house 4-128 (137) Show / Hide
Range on Protein: 1610-1734
Range on HMM: 4-128/137
Sequence Identity: 42% (53 aa)

SKFYSLVEDSDWINQLSSLLQLSGAVADLMDAQGSSVLVGLEDGWDATAQVVSLAQLLMDPYYRTMKGFCALIEKEWLALGHPFTDRSCQIQSSSgAISP
...| .|...|.  ....|. . |.|  ..  . | ||   |||| |.|.|.|||||.||||||..|.  ||||||||.|| | .|  . .|.|   ||.
vqwlsqlestqwlayikavlkaaraiarkveklavsalvhcsdgwdrtsqlvllaqllldpyyrtidglivliekewlafghkfderlggadsvs-ersp

VFLQFLDCVHQEML-RPHSYQANLDI
|||||||..|     | ... .  . 
iflqfldclyqvtkqfpsafeytarl

Phosphatase Aque_g20958.t1.AA Subfamily.MTMR3.PD 1612-1721 50 1.2e-36 114.0 In-house 1-112 (135) Show / Hide
Range on Protein: 1612-1721
Range on HMM: 1-112/135
Sequence Identity: 50% (55 aa)

FYSLVEDSDWINQLSSLLQLSGAVADLMDAQGSSVLVGLEDGWDATAQVVSLAQLLMDPYYRTMKGFCALIEKEWLALGHPFTDRSCQIQSS--SGAISP
|.| .|.. |...|| ||. .  |.. .| .|  |||   |||| |.|.|.||.||.||||||..|| .|.|.||| .|| |.||. .. |   .  .||
flsalektkwlqhlsvllkaavkvvnavdkegrpvlvhcsdgwdrtpqivalakllldpyyrtlegfkvlverewldfghkfadrcghgedsddlnercp

VFLQFLDCVHQE
|||.||||||  
vflqwldcvhql

C1 Aque_g20958.t1.AA C1 1907-1955 19 9e-06 26.41 SMART 1-61 (61) Show / Hide
Range on Protein: 1907-1955
Range on HMM: 1-61/61
Sequence Identity: 19% (12 aa)

HSFQSFKVGSTQYECSYCHHIIRDKD-------AFKCKNCSGTCHNYCKRHMPS-------NC
|...  .. .  | |..|.. |.  .       ...| .|  .||. |....|.       .|
HHWHWWRF-KPTY-CCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC

PH Aque_g20958.t1.AA PH 2001-2110 20 5.3e-15 57.09 SMART 1-82 (82) Show / Hide
Range on Protein: 2001-2110
Range on HMM: 1-82/82
Sequence Identity: 20% (23 aa)

IELEGFLFKKGGVVKNWKERYFVLNLEKGNLAYYESDKRGAKLCGTIALEAISKVEECDPIVVPSTILKSGQVGYFFKLTTNRRVFTLMTFRTSTRSQWI
...||.| ||.    .||.|.|||    . | ||...    |. |.| |. . .|.| .                 |....  |.... .   ... .|.
VIKEGWLYKKS--K-RWKKRWFVLFN--DCLYYYKDK----KPKGSIPLSDC-TVRE-P----------------CFEIHH-DRTYYFQCESEEEMQEWM

RKLTDSSKRF
. . . ... 
QAIQKAIHNN

PH Aque_g20958.t1.AA PH 2001-2108 23 2.8e-14 54.16 Pfam 1-92 (92) Show / Hide
Range on Protein: 2001-2108
Range on HMM: 1-92/92
Sequence Identity: 23% (26 aa)

IELEGFLFKKGGVVKNWKERYFVLNLEKGNLAYYESDKRGAKLCGTIALEAISKVEECDPIVVPSTILKSGQVGYFFKLTTNRR-VFTLMTFRTSTRSQW
...||.|.|||   |.||.|.|||    ..| ||..||  ... |.| |. . .|.....              . |...|  | .... .     . .|
VIKEGWLHKKG-KRKSWKKRWFVLFN--NCLYYYKDDK--YRPKGSIPLSDC-QVTKVPDN----------KRPHCFQIRT-DRRTYYFQAESEEEMNDW

IRKLTDSSK
.. . . ..
MQAIQSACR

Sequence
Name Sequence Type Origin Length Description Download
Aque_g20958.t1.AA Protein None 2113 None Fasta, JSON
Aque_g20958.t1.NA RNA None 6339 None Fasta, JSON