Gene Aque_c2425
Aque_c2425
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein domain
Protein domains of Aque_c2425.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Phosphatase | Aque_c2425.AA | Subfamily.PPM1D.PD | 1-124 | 41 | 1.9e-39 | 125.7 | In-house | 46-174 (311) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 46-174/311 Sequence Identity: 41% (54 aa) VFDGHGGRGAAQYAKSRLFPLLETS----CSHEESVKEAMRSSFLKIHSEMSSVRESWTSTREGYLSTSGTTATVVVLQPTKLYIGNVGDSAGILAVRGP |||||||. ||..|...|. .. |..|.| ||.|..||..|..| ....|. |..|.|||.||||.||... .|||...||||. .|.|. | vfDGHGGkeAakfarehlwsvikkqkkflssepedvleAireaflatheamkkklaeWpktksgllstaGttasvviirreklyvahvGDsgivlgvkep -FGKLFPKPITANHRPNNYKECQNIEQLG || .|..| .|.|.. .| ..||.|| kekklrakeltkdHkPespeEkerieelG |
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Phosphatase | Aque_c2425.AA | Group.PPM.PD | 1-124 | 30 | 8.1e-30 | 93.8 | In-house | 71-204 (459) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 71-204/459 Sequence Identity: 30% (44 aa) VFDGHGGRGAAQYAKSRLFPLLETSCSHE-------------------ESVKEAMRSSFLKIHSEMSSVRESWTstreGYLSTSGTTATVVVLQPTKLYI |||||||. ||..|...| | ... . |.||.|.||.||......|. .... . ..|||||.|..... |||. VfDGHgGaeaaefaakkLpkilkkqlkkkkdevskksaeasldnddrgekvkkalrsafleldedlseeaneke----epgkdsGtTAvvalingkklyv GNVGDSAGILAVRGpfgklFPKPITANHRPNNYKECQNIEQLG .|.||| ..| | ..| . | |.| .| . ||..| ANaGDSravLcrng-----kavplskdHkpenpeEreRIekag |
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Phosphatase | Aque_c2425.AA | Family.PPM.PD | 1-124 | 32 | 3.1e-28 | 88.5 | In-house | 50-176 (495) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 50-176/495 Sequence Identity: 32% (45 aa) VFDGHGGRGAAQYAKSRLFPLLETSCSHE-------------ESVKEAMRSSFLKIHSEMSSVRESWTstregYLSTSGTTATVVVLQPTKLYIGNVGDS |||||||. ||..|...| |. . . . |.||||.|..||....|.|. .... ..|||||.||.....|||..|.||| vfDGhgGaeaaefaakklhkilkkqlekkddeksstsaessaekvkealrkafleldeelseelneks-----agkdsGtTAvvvlirgkklyvAnaGDs AGILAVRGpfgklFPKPITANHRPNNYKECQNIEQLG .| .| ... . | |.| .| . ||..| ravLcrng-----kavelskdHkpenpeEreRIekag |
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Phosphatase | Aque_c2425.AA | Subfamily.PPM1G2.PD | 1-122 | 28 | 6.2e-22 | 68.1 | In-house | 48-158 (275) | Show / Hide |
Range on Protein: 1-122 Range on HMM: 48-158/275 Sequence Identity: 28% (35 aa) VFDGHGGRGAAQYAKSRLFPLLETSCSH-EESVKEAMRSSFLKIHSEMSSVreswTSTREgylSTSGTTATVVVLQPTKLYIGNVGDSAGILAVRGPfgk |||||||. .|.|| ..| ... |. |........ .||.. .|. . ..... ...|.||.||... .|||..|.|||.|...| vfDGhGGakvakyagkklikkiakkksfkegaleqilkdafletDeellkd----eklkd---esaGstavvvlikeeklyvanaGDsravlsskgn--- lfPKPITANHRPNNYKECQNIEQ | .. .|.|.. .| . |.. --vkalsfDhkPqeesekkriia |
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Phosphatase | Aque_c2425.AA | PP2C | 1-124 | 31 | 2.7e-21 | 78.28 | Pfam | 40-174 (284) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 40-174/284 Sequence Identity: 31% (43 aa) VFDGHGGRGAAQYAKSRLF----PLLETSCSHEES----VKEAMRSSFLKIHSEMSSVRESWTSTR--EGYLSTSGTTATVVVLQPTK--LYIGNVGDSA |||||||. ||.|....| . |. .| .|. |..|.|.|||... | . |.... .. ..||.||........| ||. |.||| VFDGHGGHQAAKYCRKHLHKAMNTILKERKSFPEGNPKDVEQALRKSFLECDTDMMFYSAPWHEQNVMHWECWHSGCTAVCAYIRNQKNILYVANCGDSR GILAVRGPFGKLFPKPITANHRPNNYKECQNIEQLG ..|. .| .. ... | |.|.| .| |.|.| AVLCRNGNAHNW-VHQLTYDHKPSNEDERRRIRQAG |
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Phosphatase | Aque_c2425.AA | Subfamily.PPM1A.PD | 1-123 | 30 | 5e-21 | 65.2 | In-house | 46-166 (309) | Show / Hide |
Range on Protein: 1-123 Range on HMM: 46-166/309 Sequence Identity: 30% (40 aa) VFDGHGGRGAAQYAKSRLFPLLETS--------CSHEESVKEAMRSSFLKIHSEMSsVRESWTSTREgylsTSGTTATVVVLQPTKLYIGNVGDSAGILA |||||.|. ...|....| . .. |..|.||||.|..||.. ... ....... ||.||.||...|.|||. |.||| ..|. vfDGHaGskvskycakhlleaileeeefkaskeksskekvkealrkgfLelDekir-klvelskged----ksGsTavvvlvspkklylancGDsRavls VRGpfgklFPKPITANHRPNNYKECQNIEQL | . | |.| . || . ||. rng-----kvvfateDHkpsdpkEkeRienA |
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Phosphatase | Aque_c2425.AA | Subfamily.PPM1E.PD | 1-124 | 33 | 6.3e-20 | 61.5 | In-house | 52-163 (269) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 52-163/269 Sequence Identity: 33% (40 aa) VFDGHGGRGAAQYAKSRLFPLLETSCSHEESVKEAMRSSFLKIHSEMSSvreswTSTREGYlsTSGTTATVVVLQPTKLYIGNVGDSAGILAVRGPFGKL ||||||| ||.||...|. || . .|. .||....| .. . . . ...||.. .||.|| ||... .||.. .||| ..|| . .| vfDGHgGveaakyaaahlhellvrqeklkedpaealkeafkltDerflq-----kaerekl--ksGstavvvliekdqlyvaWlGDsqallvrkgeavql fpkpiTANHRPNNYKECQNIEQLG . |.|.. .| . ||..| -----mkpHkPeredEkkRieeag |
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Phosphatase | Aque_c2425.AA | Subfamily.PPM1K.PD | 1-122 | 29 | 2.8e-19 | 59.4 | In-house | 42-157 (264) | Show / Hide |
Range on Protein: 1-122 Range on HMM: 42-157/264 Sequence Identity: 29% (36 aa) VFDGHGGRGAAQYAKSRLFPLLETSCSHEESVKEAMRSSFLKIHSEMSSVRESWTSTRegYLSTSGTTATVVVLQ-PTKLYIGNVGDSAGILAVRGPfgk ||||||| ||... .| ... .|. ..| . .|... .... | . . | .|||||||..|. ..| . ..||| || .| vfdGhgGssaadfvhdkleeivrrllekekdleevlkqafeeldkklkrylefsvaea--ellssGttatvsllrdGnelvlaslGdsrailcrnGk--- lfPKPITANHRPNNYKECQNIEQ .| .| .| |.. .| . | . --akkltkdhdPerkeekerika |
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Phosphatase | Aque_c2425.AA | Subfamily.LRR-PP2C.PD | 1-124 | 29 | 1.3e-16 | 50.8 | In-house | 45-154 (257) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 45-154/257 Sequence Identity: 29% (36 aa) VFDGHGGRGAAQYAKSRLFPLLETSCSHEES-VKEAMRSSFLKIHSEMssvreswtSTREgylSTSGTTATVVVLQPTKLYIGNVGDSAGILAVRgpfgK .||||||| ||..| .|. .|. ... ..... .. .|. . | | ||||..|.. | || |||||.|. . . lfdGhgGraaakfaseelykilaelldlnnanPlkslkkaykeistqi--------serp---kfiGttaasvliiedkvyianvGdsrvvlcqk----d LFPKPITANHRPNNYKECQNIEQLG | .. .|.|.. .| . |..|| gtakrlsldhkPseeseekriselG |
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Phosphatase | Aque_c2425.AA | Subfamily.PPM1L.PD | 1-124 | 33 | 8.7e-16 | 48.2 | In-house | 47-168 (273) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 47-168/273 Sequence Identity: 33% (42 aa) VFDGHGGRGAAQYAKSRLFPLLETSCSHEESVKEAMR-SSFLKI-HSEMSSVRESWTSTREGYLSTSGTTATVVVLQPTKLYIGNVGDSAGILAVRGpfG ||||||| ||..||..| . . . .. || .| |. |. || | . . ..|||| . ..| ..| . ||||| |.| . | vfdGhGGefaaefakdvlvkaiknklieldadkentvpinfsklltdeilsvdekllekakraediaGttalialvqesdlivanvGdsrGvlydkr--G KLFpkPITANHRPNNYKECQNIEQLG | |.. .|.|.. || . |.. | kai--plsfdhkpqqvkerkrikkaG |
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Phosphatase | Aque_c2425.AA | Subfamily.ILKAP.PD | 1-124 | 25 | 1.5e-15 | 47.3 | In-house | 52-182 (298) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 52-182/298 Sequence Identity: 25% (34 aa) VFDGHGGRGAAQYAKSRLFPLLE-----TSCS-HEESVKEAMRSSFLKIHSEMSSVRESWTSTregylSTSGTTATVVVLQPTKLYIGNVGDSAGILAVR |||||.|. |...|...| . .. | .....| ... .| | .|. . .. . . .|.||.||.. .||..|.||| .|| . vfDGhaGsrasefaaeklhkviveklpkedvsakdkeikkclvdafkktDeeflklaskakPv-----WkdGstavvvlvvdnvlyvanlGDskavlaRa GPFGK------LFPKPITANHRPNNYKECQNIEQLG . |. . . ... .| | .|.| . |.. | keegdkagestiasvlLskdHtpasyeerkriqkaG |
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Phosphatase | Aque_c2425.AA | Subfamily.PDP.PD | 27-121 | 23 | 6e-14 | 42.2 | In-house | 122-221 (409) | Show / Hide |
Range on Protein: 27-121 Range on HMM: 122-221/409 Sequence Identity: 23% (23 aa) SHEESVKEAMRSSFLKIHSEMS--SVRES-WTSTREGYL--STSGTTATVVVLQPTKLYIGNVGDSAGILAVRGPFGKLFPKPITANHRPNNYKECQNIE ..|..|.||....||.. ...| ..... ....| | ..||..|.......|.|.. |.||.. .|.|. . |. ........ .|.| . |. akelkveealkkaFlrlDkdislealkkleekvleeavlkvalsGacallaliegtelhvAntGDcravlgvqeeegsweavkLskdqtadneeEveRik |
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Phosphatase | Aque_c2425.AA | Subfamily.TAB1.PD | 65-124 | 37 | 2.8e-10 | 29.7 | In-house | 137-195 (336) | Show / Hide |
Range on Protein: 65-124 Range on HMM: 137-195/336 Sequence Identity: 37% (22 aa) SGTTATVVVLQPTKLYIGNVGDSAGILAVRGPFGkLFPKPITANHRPNNYKECQNIEQLG |||| |... |||. ||||| || . ..| . | . .| .| .| . ...|| gGttavvalilnnkLyvaNvGdsrAilvesekdg-ikvkQLsvdHnvdNedElkRlkdLG |
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Phosphatase | Aque_c2425.AA | Subfamily.PPM1H.PD | 23-111 | 31 | 4.5e-09 | 25.6 | In-house | 129-205 (402) | Show / Hide |
Range on Protein: 23-111 Range on HMM: 129-205/402 Sequence Identity: 31% (28 aa) ETSCSHEESVKEAMRSSFLKIHSEMSSVreswtstREGYLSTSGTTATVVVLQPTKLYIGNVGDSAGILAVRGPFgklfpKPITANHRP | . |.|| |. |. |.||.. . .. || | . | || |... |||. | ||| || .. .|. |.. | ekkiskeeLviGalesaflemDeqiare-------reayrikGGCtalvalvllgklYvanaGDsRailvrkdei-----iplsadftP |
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Phosphatase | Aque_c2425.AA | Subfamily.PPM1G.PD | 61-124 | 33 | 5.3e-09 | 25.7 | In-house | 303-361 (482) | Show / Hide |
Range on Protein: 61-124 Range on HMM: 303-361/482 Sequence Identity: 33% (21 aa) YLSTSGTTATVVVLQPTKLYIGNVGDSAGILAVRgpfGKLFpkPITANHRPNNYKECQNIEQLG . |||||.| ... ||.. |.||| .|. || . .|.|.. .| . ||. | pGkdsGttavvaLvkgkklivanaGDsRcvlsrn---Gkal--dlsiDhkPeDeveleRiekaG |
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Phosphatase | Aque_c2425.AA | Subfamily.PPM1G.PD | 1-48 | 35 | 1.9e-07 | 20.6 | In-house | 43-91 (482) | Show / Hide |
Range on Protein: 1-48 Range on HMM: 43-91/482 Sequence Identity: 35% (17 aa) VFDGHGGRGAAQYAKSRLFPLLETSCSHE-ESVKEAMRSSFLKIHSEMS |.|||||. |.|. ..| || | ... . |..|.. .|||. ... vyDGhGGkevakycakklPdllkeskaykegdvekaleeaflkvDkkll |
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Phosphatase | Aque_c2425.AA | Family.PPTC7.PD | 31-95 | 28 | 2.6e-06 | 17.4 | In-house | 63-129 (262) | Show / Hide |
Range on Protein: 31-95 Range on HMM: 63-129/262 Sequence Identity: 28% (19 aa) SVKEAMRSSFLKIHSEMSSVRESWTSTREGYLST-SGTTATVVVLQPT--KLYIGNVGDSaGILAVRG .... ...| .| .. . ....... .| .. ..|| ||||... ||. |.||| |.| || kcerlvkeskfkplkpkkllkaayaelleekvpvvGsstAcvvvldredkklesanlGDs-gflvvRe |
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Phosphatase | Aque_c2425.AA | Subfamily.PPTC7.PD | 3-94 | 26 | 5.4e-06 | 16.3 | In-house | 42-129 (263) | Show / Hide |
Range on Protein: 3-94 Range on HMM: 42-129/263 Sequence Identity: 26% (25 aa) DGHGGRGAAQYAKSRLFPLLETSCSHEESvkeamrSSFLKIHSEMSSVRESWTSTREGYLST-SGTTATVVVLQPT--KLYIGNVGDSaGILAVR || || . . .|.. | .|.. .| | .. . ....... .| .. ..|| .|||. . ||. |.||| |.| || Dgvggwreygidpsefskelmkkcerivk------eskfkerkpkkileaayqelleekvpvvGsstacivvldredkklesaNlGDS-gflVvR |
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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Aque_c2425.AA | Protein | None | 124 | None | Fasta, JSON |
Aque_c2425.NA | RNA | None | 372 | None | Fasta, JSON |
Aque_c2425.AA.PD_1-124 | Protein Phosphatase Domain | None | 124 | None | Fasta, JSON |