• Phosphatome.Net

Gene M01A12.4

M01A12.4
Species: C.elegans
Alias: M01A12.4
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: ClassicPTP_Unclassified
Protein domain

Protein domains of M01A12.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase M01A12.4.AA PTPc 1-245 11 9.8e-12 43.39 SMART 5-308 (308) Show / Hide 
Range on Protein: 1-245
Range on HMM: 5-308/308
Sequence Identity: 11% (38 aa)

IQTHIINF--------------------------QKNRFT-NVACFDEILDR--D--------NEDFYVHANTFRT--PYGNFLISQAPNDSTNGDHLHL
.  .. ..                           |||.. .. |.|.   .  .        . ..|..||  ..   .  .   |.| ..|  |. . 
EFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIEDFWRM

MWIYNVQTVVCLVSPEEA-------------GGYFVPKEGETFTSFQKYQMKTIGIFDEKQGVTVYQCELKSYKAPK-KLNRRMIYIICCD---------
 | ......|.|....|                |.  .             .| |          .. ..||.. ..   ..| ...  ..         
VWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE------------PMTYG---------HITVTCKSEEKCPDDYTMRTFEVTNTGCNCKYSMAC

------TSVGSIRSPRQQTV-----IMEYMWAFEEANAIENG-----------VALADAKTTVLVHAIAGTRRCASFVATSVMCKQLLEAGNFSAMETWF
      |       | ...      .......... .. ...           ..  .. . ..||  ||  |...|.| ..|| |. .   ..  ... 
SETRTVTHYHYTNWPDHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVK

EMRKRRAHTCTRKHDFFSSIYTFFAFCVQ
.||. |.. .   .......|   .. ..
MMRNQRPG-MVQTEEQYIFCYRCILEYIK
Phosphatase M01A12.4.AA Y_phosphatase 7-246 17 2.9e-27 96.99 Pfam 1-243 (243) Show / Hide 
Range on Protein: 7-246
Range on HMM: 1-243/243
Sequence Identity: 17% (47 aa)

NFQKNRFTNVACFDEILD------RDNEDFYVHANTFRTPYG---NFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG------YFVPK-EGET
|  |||.... |.|           |. ..|..||  ..||.   .. . |.| ..| .|. .  | ......|.| ...| |       .. |  . ..
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

FTSFQKYQMKTIGIFDEKQGVTVYQCELKSYKA---PKKLNRRMIYIICCDTSVGSIRSPRQQTVIMEYMWAFEEANAIENGVALADAKTT---VLVHAI
. .. ..| ...     ....||.. |..  ..   ...  .   |.   | .| .     | . ...... .....         .       ..||  
PMTYGDFQVTCVSEEH-CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPES----QPKSMLDFIRQVRKWQP--------NPDHGCPPIVVHCS

AGTRRCASFVATSVMCKQLLEAGNFSAMETWFEMRKRRAHTCTRKHDFFSSIYTFFAFCVQC
||  | . |.| ..|| |. . | .. .... .||. |.. ..       . | |   |...
AGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQ-----TEEQYIFCYQCILE
Phosphatase M01A12.4.AA Subfamily.N_Nematode_5.PD 7-241 18 2e-17 54.2 In-house 25-254 (258) Show / Hide 
Range on Protein: 7-241
Range on HMM: 25-254/258
Sequence Identity: 18% (44 aa)

NFQKNRFTNVACFDEI--LDRDNEDFYVHANTFRTP--YGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG---YFVPKEGETFTSFQKYQM
| .||| ..| . ||      |..| |..|.. . .    .... | |  .|  |   ..   ....|| ||..||.      ||.| .... ..|   .
nlkknrskdvkilDetrVkltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvedeelketavsffpletgdylnlgkmfi

KTIGIFDEKQGVTVYQCELKSYKapkKLNRRMIYIICCDTSVGSiRSPRQQTVIME-YMWAFEEANAIENgvaladakTTVLVHAIAGTRRCASFVATSV
.  .  ...  . |. |. . .   . .  .. .  ..|   . . | ... ...  .  . . . ..|        ..|.|.  .|. | ..|...||.
nnrkvevkedekkeytvevlpeg---csesvfakvyhlttWkkk-kvPdkvkkvikraiekvlskkqgkn--------apvvvvsdlGlgRagtflllsv

MCKQLLEAGNFSAMETWFEMRKRRAHTCTRKhDFFSSIYTFFA
..|| .  ..   |.  ..|. |.. ..   ....|.|. .. 
aieqlnngkepnideilkkirsqRpgavesl-iqyasvyaavl
Phosphatase M01A12.4.AA Subfamily.R_Ecdysozoa.PD 7-229 17 1.6e-13 41.3 In-house 27-254 (269) Show / Hide 
Range on Protein: 7-229
Range on HMM: 27-254/269
Sequence Identity: 17% (40 aa)

NFQKNRFTNVACFDEI------LDRDNEDFYVHANTFRTP--YGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGGYfVPKEG--ETFTSFQK
|  |||. ..  ||.       .  ...  |. |.  ..     .|...|.| ..| ||   ...  .|...| |   .|..|    |. . ...  .|.
nalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknrk-cakyWpiedevqygd

YQMKTIGiFDEKQGVTVYQCELKSYKAPKKLNRRMIYIICCDTSVGSIRSPRQQTVIMEYMWAFEEANAIEngvALADAKTTVLVHAIAGTRRCASFVAT
.  .....  .  . ..   |.    ..| .      .     . |.. . .....   .| ..    |. ... ..||  ||. | . ||| ... .||
ilvklvs-eekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelykln---klsgsrsPivvhCsaGvgrsgifval

SVMCKQLLEAGNFSAMETWFEMRKRRAHTCTRK
 .  . . .||  ..|..|.   ..        
dlllqqlkaedkvdifetvkkLrsqrnllvqsl
Phosphatase M01A12.4.AA Subfamily.N_Nematode_4.PD 7-233 21 3.7e-13 40.3 In-house 26-253 (264) Show / Hide 
Range on Protein: 7-233
Range on HMM: 26-253/264
Sequence Identity: 21% (50 aa)

NFQKNRFTNVACFDE----ILDRDNEDFYVHANTFRTPYG-NFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAG----GYFVPKEGETFTSFQKY
| .|||.... | ||    . .|| .  |.||.  | | . ... .| | . |  |  |...   ...|| | . .| |..|.. |. . | ||... . 
nsdknryadilcidetrvvlknrdpdndyihaswmrmPdkfryistqGPlketlsdfwhmvytekiavvvmlcdlieegvekcaryypeksekvvkfGky

QMKTIGIFDEKQGVTVYQCeLKSYKAPKKLNRRMIYIICCDTSVgsiRSPRQQTVIMEYMWAFEEANAIENgvalADAKTTVLVHAIAGTRRCASFVATS
   |    ....  ||  .  ||..     ..     |      | |.  .. .   .   |. .     . .. . ||  ||  | |..|       ..
ritlvekkeeviadvilns-lkvtntekkkdapseplvvkhvqv---dwwrdqvaPldaapviklykavkk----kkkekPivvhcsaGvGrtatlvGid

VMCKQLLEAGNFSAMETWFEMRKRRAHTCTRKHDFF
 | ..   ..   |.|. | ..   .. |       
yatirirenseievldivrelramrlkavqshlqfl
Phosphatase M01A12.4.AA Subfamily.N_Nematode_1.PD 8-229 23 6.2e-13 39.5 In-house 27-250 (265) Show / Hide 
Range on Protein: 8-229
Range on HMM: 27-250/265
Sequence Identity: 23% (53 aa)

FQKNRFTNVACFDE---IL-DRDNEDFYVHANTFRTPYG--NFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGGYfvpKEGETFTSFQKYQMKt
.|||...| | |.   .| .      |.|||   ||     |. .||| |.|  |  ...   .|...| |    | | .|  | |.. .. ...    |
adknrykdvgcldknrvklaeeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckliekgkk---kcaeyfpakegekle-

igiFDEK-QGVTV-YQCELKSYKAP-KKLNRRMIYIICCDTSVGSIRSPRQQTVIMEyMWAFEEANAIENGVALADAKTTVLVHAIAGTRRCASFVATSV
.|| | .||  . . |  .   ....  .. .    ... ...  . .           .  |.|   |    |. ..||  ||  |  . || . .. .
---fkekgqkitvenslgvkkleedeevikvtvlevegaGektrkvthyqWtdWPdr-GvPpadlaalelleavrgskgPivvhCsaGiGrtGtivaiey

MCKQLLEAGNFSAMETWF-EMRKRRAHTCTRK
|||  . ..||    ..|..|...        
ildkllegkqiedmeklvkkireqrnysiqtd
Phosphatase M01A12.4.AA Subfamily.N9.PD 4-230 23 1.7e-12 38.3 In-house 23-261 (275) Show / Hide 
Range on Protein: 4-230
Range on HMM: 23-261/275
Sequence Identity: 23% (56 aa)

HIINFQKNRFTNVACFDE------ILDRDNEDFYVHANtFRTPY---GNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAG----GYFVPKEGET
.  | .|||.|.| |.||       || |..  |..|| |   |     |. .| | . |  |.  ..|  .| ..|     .| |    | .|.| |. 
lranleknrytdvlcydetrvklakldedeasdyinan-fvdGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgqywpleees

FTSFQKYQMKTIGIFDEKQgVTVYQCELKSYKapKKLNRRMIY-IIccdTSVGSIRSPRQQTVIMEYMWAFEEANAI-----ENGVALADAKTTVLVHAI
..| .........  |..  .| . |.|  |  .. .|....  .   .|      |.. . ... . .  |. |       .  ..  ..||  ||  |
saefgdlsvsnveveveed-ykvrvleiknvk--teesrkvthfqf---lswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPivvhcs

AGTRRCASFVATSVMCKQLLEAGNFSAMETWFEMRKRRAHTCTRKH
  .|..  .  ..| | |.   .||   .|..||..   ..     
aGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpe
Phosphatase M01A12.4.AA Subfamily.N12.PD 7-237 19 2.9e-12 37.2 In-house 32-262 (270) Show / Hide 
Range on Protein: 7-237
Range on HMM: 32-262/270
Sequence Identity: 19% (47 aa)

NFQKNRFTNVACFDE---ILDRD---NEDFYVHANTFRTPYGN--FLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG----YFVPKEGETFTSF
| .|||. ..  .|.   .|...   ... |. ||  . ..|.  .. .|.|  .|  |. ...| .||. || .    | |      . |.|||. . |
nvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCeryWpeegeeelef

QKYQMKTIGIFDEKQGVTVYQCELKSYKAPKKLNrRMIYIICCDTSVgsirsPRQQTVIMEYMWAFEEANAiengvalaDAKTTVLVHAIAGTRRCASFV
........     ... .. . ...  |. .|.. .. |    |  |     |.... ..| .....| .         . .. ..||  ||  |    .
gefevtleeekavdddflirtLkveaqkesrkvy-qfhytaWPDhgv-----Pssaksllelielvrelqe--------sedaPlvvhCsaGvGrtGtii

ATSVMCKQLLE---AGNFSAMETWFEMRKRRAHTCTrKHDFFSSIY
|   . ..| .   . ...  .   |.||.||      .. .. .|
aidyvrellkaekipeeldvfdlvlelrkqraalvq-tkeqyelvy
Phosphatase M01A12.4.AA Subfamily.N14.PD 7-224 20 3.7e-11 33.6 In-house 26-255 (275) Show / Hide 
Range on Protein: 7-224
Range on HMM: 26-255/275
Sequence Identity: 20% (47 aa)

NFQKNRFTNVACFDEI-----LDRDNEDFYVHANTFRTPYG----NFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG----YFVPKEGETFTS
| .|||| .|  ...        ..|.. |. | . ... |    .....|.| . |  |. ...|  .|| .| | . || |      ..||...   .
naeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeksfkylPkleskkkt

FQKYQMKTIGIFDEKQGVTVYqCELKSYKAPKKLNRRMIYIICCDTSvgSIRSPRQQTVIMEYMWAFEEANAIENGVA--LADAKTTVLVHAIAGTRRCA
 .  . | .  | |. . ..    || .  | | .| ....   | .    . |.  .  ....  ..      |       ..|||||  ||  |    
vefgkfkvttkfsedsdsvit-tglklkhlpskeertvwhlqytDWp--dhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPvlvhCsaGvGrtG

SFVATSVMCKQLLEAGNFSAMETWFEMRKRRAH
. . .. . | .  .    ..   .||.| .  
vlilsdlliatlehneeidikkvlarLrkqrml
Phosphatase M01A12.4.AA Subfamily.RG.PD 31-239 20 5.5e-11 33.3 In-house 57-258 (264) Show / Hide 
Range on Protein: 31-239
Range on HMM: 57-258/264
Sequence Identity: 20% (42 aa)

YVHANTFRT--PYGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEE----AGGYFVPKEgETFTSFQKYQMKTIGiFDEKQGVTVYQCELKSYKAP
|. |.  .      .....| |  .|  |  ...|  |.|..| | . .|        . ||. ..  ........ .   .... .|| .  ||. |  
YinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrdedvyWPkk-deplelealkvtlls-keklskytvrdfvlkntkdd

KKLNRRMIYIICcdTSVGSIRSPRQQTVIMEYMWAFEEANAIENGvaladaktTVLVHAIAGTRRCASFVATSVMCKQLLEAGNFSAMETWFEMRKRRAH
|...|..    .  |.   . || ...  . ..   | ||  |.|         ..||  ||. | . ..| . . .|| .  ...   .|..| . .| 
kekervvrqyhy--tkWPdmgsPestlfvlifvkkeeaankeeaG--------PivvhdsaGvgragtyialdtllqqlekeeavnvyqvlklirakRpg

TCTRKHDFfSSIYTF
. ..   ||      
lvtteEqy-vfiyda
Phosphatase M01A12.4.AA Subfamily.R_Nematode_3.PD 28-239 20 8.6e-11 32.5 In-house 50-262 (267) Show / Hide 
Range on Protein: 28-239
Range on HMM: 50-262/267
Sequence Identity: 20% (45 aa)

EDFYVHANTFRTPYGNFLI-SQAPN--------DSTNGDHLHLMWIYNVQTVVCLVSPEEaggyfvpKEGETFT--------------SFQKYQMKTIGI
.| ..|||    | |. || .|.|          ||.  .. ..  ..|. || | .  |       ..||..|.....|.. |  |.. .|   . .. 
kddfihAnvvecpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvmlcdfve-------edgeeeekcseYypekvdgelkfegvsvkctdi

FDEKQ-GVTVYQCELkSYKapkklnrrmiyiiccdtsvgsirSPRQQTVIMEYMWAFEEANAIENGVA-------LADAKTTVLVHAIAGTRRCASFVAT
...                          . || . .. . .| || |..   ||.|.|| ..|  | |...|. . .  ...   ... ..   |.|| 
kkelsedvekrtlvv-tfe-----------------------kkkeftvthllykgWkelnapeepkealelikfveksktpvvVHCsdGisRsatlaai

SVMCKQLLEAG-NFSAMETWFEMRKRRAHTCTRKHDFFSSIYTF
||.  . . ..  .|.                            
elgyqliikskgkldllslikelrkqRagaiqtelelafvilgi
Phosphatase M01A12.4.AA Subfamily.R_Nematode_2.PD 6-229 18 1.6e-10 31.5 In-house 28-246 (261) Show / Hide 
Range on Protein: 6-229
Range on HMM: 28-246/261
Sequence Identity: 18% (41 aa)

INFQKNRFTNVACFDEI---LDRDNEDFYVHANTFRTPYG--NFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAG----GYFVPKEGETFTSFQK
.. .|.|. .| | .|       |..   .|||   |.     |...|.| . |  |   ..  ..|...| |    |..| | .  ........|| . 
lpkdkhRypdvPCkpetavevivdgkrvpihanwvptagnpkrfiatqgPlentsedfWamviqekvekivmlcqkvekekekceeYfpletsqkldlgr

YQMKTIGIfDEKQGVTVYQCELKSYKAPKKLNRRMIYIICCDTsVGSIRSPRQQtvimeymwafeeANAIENGVALADAKTTVLVHAIAGTRRCASFVAT
 ..     ...  ||  .. .|.. | .              |. .            |.|   .. ...  ..||  ||  |  .|..| .. ..... 
fsiktvsa-ekilkdeiekrtlkvedstgkfatrtvthyqyee-WpdrgvPksh------------aelfeLlelvkksekPivvhCsaGiGRtmafigt

SVMCKQLLEAGNFSAMETWFEMRKRRAHTCTRK
 . .  |.  |.|. | ..  ..          
eylareveadptieltealkelrehRwkgiqte
Phosphatase M01A12.4.AA Subfamily.R_Anemone_2.PD 3-229 19 1.7e-10 31.8 In-house 23-247 (262) Show / Hide 
Range on Protein: 3-229
Range on HMM: 23-247/262
Sequence Identity: 19% (45 aa)

THIINFQKNRFTNVACFDEI------LDRDNEDFYVHANTFR--TPYGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGGYFVPKEGETFTSf
.. .| .|||..|.  .|.       |. ...  |. ||     .   ... .|||   |  |   ..|  | ...| |   ||.|   | .      | 
lepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltqeeergkakvhryWPskgs-

QKYQMKTIGIFDEkQGVTVYQCELKSYKAPKKLNRRMIYIICCdTSVGSIRSPRQQTVIMEYMWAFEEANAiengvalADAKTTVLVHAIAGTRRCASFV
..|.  .. . .|   .. |     . |  .. . |..    . ||     .| . . ... .   |.|..          .....||  ||  |   |.
rsygklvvelkee-velsdyvlrsfkvkrteeeeerqvrqfhy-tsWpdegvpesgaslldlvrqvekaqq-------esgagpivvhcsaGvGrtGvfi

ATSVMCKQLLEAGNFSAMETWFEMRKRRAHTCTRK
| ... ... . .    ..|  ..|..|      |
avdillerikaealvdvfqtvkqlreqrnlmvqtk
Phosphatase M01A12.4.AA Subfamily.N5_RR.PD 25-224 21 2.1e-10 31.3 In-house 48-245 (265) Show / Hide 
Range on Protein: 25-224
Range on HMM: 48-245/265
Sequence Identity: 21% (45 aa)

RDNEDFYVHANTFRTPYG---NFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG----YFVPKEGET--FTSFQKYQMKTIGIFdEKQGVTVYQ
.|..  |. ||  . . .    ..  | |  .|  |  ....  .|| .| |   .||       . |.. ..     ... ..|. .||... .| .  
ededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedyeiserygdveikveeiv-erndysvrk

CELKSYKApkkLNRRMIYIICcdTSVGSIRSPRQQTVIMEYMWAFEEANAIENGvALAdaktTVLVHAIAGTRRCASFVATSVMCKQLLEAGNFSAMETW
||. .    ..|.....    |.    .||.. . ... .   ||..  ||   ||     |.||  ||  |   |.|.|. ..|| | .    ...  .
lvlkyler---versvkhywy--tdWPdhksPddintlldlvleveesreeena-kla----PvvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkiv

FEMRKRRAH
.|  |    
cnlrldrGG
Phosphatase M01A12.4.AA Subfamily.RB.PD 5-232 18 1e-09 29.0 In-house 24-249 (261) Show / Hide 
Range on Protein: 5-232
Range on HMM: 24-249/261
Sequence Identity: 18% (44 aa)

IINFQKNRFTNVACFDE------ILDRDNEDFYVHANTFRTP--YGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGGYFVPKEGETFTSFQK
.| .||||||.. .|.       |. .... |. || .       ... .| |  .|  |  ...|  .....| |.   | |   . .   ... . | 
avnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeYWPadeepvl

YQMKTIGIFDEK--QGVTVYQCELKSYKApKKLNRRMIYIICCDTSVgsirsPRQQTVIMEYMWAFEEANAIEngvalaDAKTTVLVHAIAGTRRCASFV
  .. .  ||  .  .. . .... |  |.  |.. ..   | .|     |.. . ..... ...||   .       .|. ..||||  |   |.|   
yGdikvtllaekeldewvirefkiekgke-krkvrqyhftsWpdhgv-----Pektktlldfvrtvreaiekk------askkPivvHCsaGvGRtGtfi

ATSVMCKQLLEAGNFSAMETWFEMRKRRAHTCTRKHDF
. ... |      . .  |.|..|..    ....    
aldrllqaieendyvdvfgvvaelReeRnllvqtekqy
Phosphatase M01A12.4.AA PTPc_motif 127-241 16 1.6e-09 38.85 SMART 1-92 (92) Show / Hide 
Range on Protein: 127-241
Range on HMM: 1-92/92
Sequence Identity: 16% (20 aa)

LNRRMIYIICCDT-----SVGSIRSPRQQTVIMEYMWAFEEANAIENGVALADAKTTVLVHAIAGTRRCASFVATSVMCKQLLEAGNFSAMETWFEMRKR
  ... |    |      .| .         |.|.......                ..||  ||  |.. |.| ..|. |      ..  .|. |||| 
TVHHYHYTNWPDHVEKDSGVPE-------DSILEFIRHVRK---------------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQ

RAHTCTRKHDFFSSIYTFFA
|.. .. .. .   ..    
RPGMVQTEEQYIFCYRCILE
Phosphatase M01A12.4.AA Subfamily.N_Choan_1.PD 7-224 18 2.8e-09 27.7 In-house 26-242 (262) Show / Hide 
Range on Protein: 7-224
Range on HMM: 26-242/262
Sequence Identity: 18% (40 aa)

NFQKNRFTNVACFDEI---L---DRDNEDFYVHANTFRT--PYGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG----YFVPkEGETFTSF
| .|||..|.  .|     .   .....  |. ||   .     .....|.|  ..  .  ...| ..|...| .    |||. | .... ... ....|
nvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryWP-denselkl

QKYQMKTIGIFDEKQGVtVYQCELKSYKAPKKLNRRMIYIICCDTSVgsirsPRQQTVIMEYMWAFEEANAiengvalADAKTTVLVHAIAGTRRCASFV
..   ..|. .   . .|.  .. ..  ... |.   |. |     | . . ..|.  | ..|.. |.....|  ||  |  ...|   ..|.. |  . 
gdvtvkslseeekktyi-erkfkleresgetreveqlaytaWPdhGv-----Pattkellefrkavlkatk-------kktkaplvihCsaGvGrtGtyi

ATSVMCKQLLEAGNF-SAMETWFEMRKRRAH
 .  ..  |.||.|                 
alDrlvkaveekaealdvkavvaelrkernl
Phosphatase M01A12.4.AA Subfamily.N_Nematode_6.PD 4-79 29 3.8e-09 27.2 In-house 21-100 (253) Show / Hide 
Range on Protein: 4-79
Range on HMM: 21-100/253
Sequence Identity: 29% (23 aa)

HIINFQKNRFTNVACFDE--ILDRDNEDFYVHANTFR--TPYGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEA
. . ..||.||. |.|   .   |.||||.|||  .  | .  .. .||| ..|  .  ...    |. .| |.   |  
flkfkdrnrytniqCcdagrlkladdedfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelvek
Phosphatase M01A12.4.AA Subfamily.N_Choan_2.PD 23-229 19 6e-09 26.3 In-house 43-251 (266) Show / Hide 
Range on Protein: 23-229
Range on HMM: 43-251/266
Sequence Identity: 19% (40 aa)

LDRDNEDFYVHANTFR---TPYGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG----YFVPKEGETFTSFQKYQMKTIGIFDEK-QGVTVY
|..|..  |. ||  |       ... ...| ..|  ... ..|  .|...| .   || |      . |.| .. ..... ..|... .|| .|  . .
leedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkladgkikvlalseekeegyilt

QCELKSYKAPKKLNrRMIYIICCDTSVGSIRSPRqqTVIMEYMWAFEEANAIENGvaLADAKtTVLVHAIAGTRRCASFVATSVMCKQLLEAGNFSAMET
 .|.  .  ..|     |    | .| .       .   . .  ... .....   |..|.  .|||  |||   ..|.  ... | | ..   ..   |
rlrlekkgetrrlv-HfwyntWpdhgvpreedss--lstdqllkmlravrrvrke--ldkae-PllvHcsaGvgRtGtliaiDiavrlLeetkkvdvlai

WFEMRKRRAHTCTRK
.|| |          
ieelRkdRmalvqhp
Phosphatase M01A12.4.AA Subfamily.N3.PD 7-228 17 8e-09 25.9 In-house 26-245 (261) Show / Hide 
Range on Protein: 7-228
Range on HMM: 26-245/261
Sequence Identity: 17% (41 aa)

NFQKNRFTNVACFDEI---LDRDNEdFYVHANTFRT--PY----GNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG----YFVPKEGETfTS
| .|||. ... .|.    |.  .   |. ||.     |      .....| | ..|  |  ...|  .....| | .  | |      . |..... ..
nlaknryrdilpydatrvklkeset-dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGrvkChqyWPetede-le

FQKYQMKTIGIfDEKQGVTVYQCELKSYK-APKKLNRRMIYIICCDTSVgsirsPRQQTVIMEYMWAFEEANaiengvalADAKTTVLVHAIAGTRRCAS
| .....     ||.. . . .  ||  .   ..   .. |.   | .|     | ... ..|..   ...         . ... |.||  ||  |   
fgefsvrceke-detksyvlrelvlkdketkeerkilqlqylaWpdhgv-----Pddsadflefvervrklr--------sgkeePvvvhCsaGigrtGv

FVATSVMCKQLLEAGNFSAMETWFEMRKRRAHTCTR
...  .    . .| ..  ..   .|| .||     
lilletalalieaaepvypldivrtmrdqramlvqt
Phosphatase M01A12.4.AA Subfamily.R_Anemone_1.PD 7-231 20 1.5e-08 25.5 In-house 25-245 (258) Show / Hide 
Range on Protein: 7-231
Range on HMM: 25-245/258
Sequence Identity: 20% (45 aa)

NFQKNRFTNVACFDE---ILDR---DNEDFYVHANTFRTPY--GNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGGYFVPKEGETftSFQKYQ
| .|||....  .|.   .|..   |.|  |. |   |.     .|...|||  .| .|  ...| ......| | . .|...   .  | .||   .. 
nkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnliegekkkchqYwPd--stekyg

MKTIGIFDEKQGVTVYQCELKSYKAPKKlNRRMIYIICCdTSVGSIRSPRQQTVIMEYMWAFEEAnaiengvALADaKTTVLVHAIAGTRRCASFVATSV
.  ...   .  ..|.  |. .. ..|... .   |.      |...| .....   ..||. .. |.||  ||  |   |.. . | .|. .      .
elrvslrkkevfadyiirtlvlskkket-eerevvqyhf-tvWpdkgvPqyatavLglrrkvqks-------slag-arpvvvhCsaGvgRtGaflvida

MCKQLLEAGNFSAMETWFEMRKRRAHTCTRKHD
..   .|. |.|. . |.               
mleqakkekvvDifnyvkairedrphmvqtkeq
Phosphatase M01A12.4.AA Subfamily.N23.PD 42-231 17 2.3e-08 24.3 In-house 147-337 (350) Show / Hide 
Range on Protein: 42-231
Range on HMM: 147-337/350
Sequence Identity: 17% (33 aa)

GNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEA-----GGYFVPKEGETfTSFQKYQMktiGIFDEKQGVTVYQCELKSYKAPKKLNRRMIYIic
.|...|.|  || .|   ..|   ....|.|.. .|        |.  .|||| ..|.....    . ....  .  .  |.  . . .  |.  .    
PpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPideget-nlfgdlrv---slkslrssegwiervlhlqhndvstvrlvchl--

CDTSVGSIRSPRQQTVIMEYMWAFEEANAIENGVAL-ADAKTTVLVHAIAGTRRCASFVATSV-MCKQLLEAGNFSAMETWFEMRKRRAHTCTRKHD
|.   |  |    ...... . |.| | .. .    ...  ...|  ||  |   |      . .   . |    .. . ..|.| .    |.    
htttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltagngiiniprvvrrlrqqRkymvqkkvi
Phosphatase M01A12.4.AA Subfamily.R_Sponge_2.PD 6-225 19 2.8e-07 21.2 In-house 24-243 (262) Show / Hide 
Range on Protein: 6-225
Range on HMM: 24-243/262
Sequence Identity: 19% (43 aa)

INFQKNRFTNVACFDEI---LDR--DNEDFYVHAN---TFRTPyGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG-----YFVPKEGETfT
.|  ||||...  .|.    |     ..  |. |.    .. . . .. .|.|  .| .|   ..| |.|.|.| |.  || ||.  |..|. ... |. 
envgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrr-kayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPekvdee-v

SFQKYqMKTIGIFDEKQGVTVYQCELKSYKAPKKLN--RRMIYIICCDTSVgsirsPRQQTVIMEYMWAFEEANAIENgvaladaKTTVLVHAIAGTRRC
  |.    . .  .. . .|.. |. .. .  ..  ..   ...|     |...| ..| .   ..|.  ..       .... |.  .|  |  .|.| 
eygkf-kvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehev-----Pkdatsllelikrvlraqkksg-------nkaitvvCsdgvgrt

ASFVATSVMCKQLLEAGNFSAMETWFEMRKRRAHT
 .. ..| . ..    |.  ..| .|         
Gtfialdsvlerlkaeeeidvfevlktlrtkrigl
Phosphatase M01A12.4.AA Subfamily.N13.PD 7-228 17 3.5e-07 20.9 In-house 26-243 (259) Show / Hide 
Range on Protein: 7-228
Range on HMM: 26-243/259
Sequence Identity: 17% (39 aa)

NFQKNRFTNVACFDEILDR-DNEDFYVHANTFRTPYGN----FLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG-----YFVPKEGETFTSFQK
| .|||. ||  .||   . ..|  |. |.  . | |.    ....| |   |  |  ...|  ... .. . .  | |      |.  ..... .  ..
nkdknryrnvlPydetrvklgdeggyinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPerknkklkvsnr

YQMKTIGIfDEKQGVTVYQCELKSYKAPKKLN-RRMIYIICCDTSVGSirSPRQQTVIMEYMWAfeeanaiengvaLADAKTTVLVHAIAGTRRCASFVA
.... ...  ...| .| . ..|  .. .  .  .. ..   | .| |  |. .   .. ..              |.. .. ..||  ||  |  ....
levellkv-qkldgfvvralavkdsesgesrevahlnfvkwPdhgvPs--saaelvqfvaevrl------------lqtdagPivvhcsaGiGrsGvlit

TSVMCKQLLEAGNFSAMETWFEMRKRRAHTCTR
  |.   .    .|   |.  ..|..|      
idvvlglierdkefdvkeivrklreqrqgvvqt
Phosphatase M01A12.4.AA Subfamily.RK.PD 7-205 16 2.4e-06 17.8 In-house 29-228 (267) Show / Hide 
Range on Protein: 7-205
Range on HMM: 29-228/267
Sequence Identity: 16% (35 aa)

NFQKNRFTNVACFDEIL------DRDnEDFYVHANT---FRTPyGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG-----YFVPKEGET-F
| .|||....  .|  |      | | .  |. |.    .. |  .|.. | | ..|  |   |.. .|  ..| |   . . |      . |...|. .
nreknrsmdilaydrslvflisvdgd-ssdyinaalidsykrp-aafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyWPedtevry

TSFQKYQMKTIgiFDEKQGVTVYQCEL--KSYKApKKLNRRMIYIICCDTSvgsiRSPRQQTVIMEYMWAFEEANAIengvalaDAKTTVLVHAIAGTRR
  ..   ...    |..  | ... |   ..... ... |.. ..   .        | ... .....   .. ..        . ...||  ||. |  
gdikvelveae--ldadlvvrifrveklargqee-irevrqfqflgWpeyr----dvPvskrsllklirrvkksqee-------eeeGrivvhClaGaGr

CASFVATSVMCKQLLE
 |.| ..... . .  
sGtfiaidivlemier
Phosphatase M01A12.4.AA Subfamily.RA.PD 42-229 17 6.5e-06 16.6 In-house 70-251 (266) Show / Hide 
Range on Protein: 42-229
Range on HMM: 70-251/266
Sequence Identity: 17% (33 aa)

GNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEAGG----YFVPKEGETftSfqkYQMKTIGIFDEKQ--GVTVYQCELK-SYKAPKKLNRRMIYI
.|. .| | . |  |   ..| .. .|.| |   .| .      . |.||    .   |   .. . ||.    .|| .  ..   .| .. .|..  . 
dkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaqywpdeGlv--t---yGeirvevkdetvledytvrdflvtqlpdatrekksrlvrq

ICcDTSVGSIRSPRQQTVIMEYMWAFEEANAIEngvaladAKTTVLVHAIAGTRRCASFVATSVMCKQLLEAGNFSAMETWFEMRKRRAHTCTRK
  ||   .  | .   ..... . .. .  .       |. .. ||  ||. |  .|.. . . ...   .    .|.  ..|..|..    .  
fh-ftswpevGvpaegkGmlkllkkvkklqqqs-------anhpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtl
Phosphatase M01A12.4.AA Subfamily.N_Nematode_egg.PD 29-90 30 7.6e-06 16.4 In-house 54-119 (257) Show / Hide 
Range on Protein: 29-90
Range on HMM: 54-119/257
Sequence Identity: 30% (20 aa)

DFYVHANTFRT-P-YGNFLISQAPNDSTNGDHLHLMWIYNVQTVVCLVSPEEA--GGYFVPKEGET
| ..|||  .  | . .|...|||   |  |   ...  .|| .| | |  |.    |. ||  . 
ddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakeserceyywpkaese
Sequence
Name Sequence Type Origin Length Description Download
M01A12.4.AA Protein None 262 None Fasta, JSON
M01A12.4.NA RNA None 786 None Fasta, JSON
M01A12.4.AA.PD_1-246 Protein Phosphatase Domain None 246 None Fasta, JSON