M05D6.3
Species: C.elegans
Alias: M05D6.3
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Protein domain

Protein domains of M05D6.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase M05D6.3.AA PTPc 69-359 19 9.9e-47 162.49 SMART 1-308 (308) Show / Hide
Range on Protein: 69-359
Range on HMM: 1-308/308
Sequence Identity: 19% (67 aa)

LLNQMHTSAMTY-------------PNTYDKFLNNM--DMNRIP-HLYCFDHSRVELAPQDGK------DDFYNASWVDGYSKKSAYIFAQAPFNDHTEY
 ..... .  ..             . |  .. .|.  |.|| . .  |.||.|| | | .|.      .|. ||...||| .. .|| .|.|  .||  
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPL-PHTIE

IFWRMVSERKPSMILVFGDIDEK--QKRKAPYDISDRGFEKSFLHEFGAKSLEECELKAKICRKFWPEKRSKKDFPTLSIQASDDHS---ETHMKTFNLT
 ||||| . | . |    ...||                             .  ... . | ..||..  .. .  ....  . ..   . .|.||..|
DFWRMVWQQKCHIIVMLCNCMEKCTE-------------------------NR-DQNGREKCHQYWPDE--PMTYGHITVTCKSEEKCPDDYTMRTFEVT

VTEK--------KQDHQTVLMHFYEWADASKLP---EYMLDMRASIKLQYIRS-----------SKKTGVC-IGPIMLVCATGVEKCAISATIDIIVSRI
 |.         .. ..    |.  | |  . |   . .||..  .. .. .|           ||... |  |||. .|  |.  ..  ..|||.. .|
NTGCNCKYSMACSETRTVTHYHYTNWPDH-GVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQI

TEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAV
..   | ...... . .||.|.. |   |.  ........ 
EN---VDIFQIVKMMRNQRPGMVQTEEQYIFCYRCILEYIK

Phosphatase M05D6.3.AA Y_phosphatase 90-356 21 1.2e-30 108.97 Pfam 1-243 (243) Show / Hide
Range on Protein: 90-356
Range on HMM: 1-243/243
Sequence Identity: 21% (62 aa)

NMDMNRIPHLYCFDHSRVELAP--QDGKDDFYNASWVDG-YSKKSAYIFAQAPFNDHTEYIFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDRGFEKS
|.. || .   |.||.|| | |   |. .|..||...|| | .. ||| .|.|   ||   ||||| . | ..|    ...|...               
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMP-HTIEDFWRMVWQQKCTCIVMLCNCMEMGR---------------

FLHEFGAKSLEECELKAKICRK----FWPE--KRSKKDFPTLS--IQASDDHSETHMKTFNLTVTE--KKQDHQTVLMHFYEWADASKLPEY----MLDM
                   ..|    .||.  .  .. .  ..  ..  . ... .. ||..|  .  |.. ..    |. .| |  . ||     |||.
-------------------DEKTCHQYWPDNKEGQPMTYGDFQVTCVSEEHCPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDH-GVPESQPKSMLDF

RASIKLQYIRSSKKTGVCIGPIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
.  .. ..   .   |   .||. .|  |.   .  ..|||.  ....|. |  ... . .  || |.. |   |   .. .. 
IRQVRKWQP--NPDHGC--PPIVVHCSAGCGRTGTFCAIDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE

Phosphatase M05D6.3.AA Subfamily.N_Nematode_5.PD 75-357 16 8.5e-28 88.2 In-house 9-256 (258) Show / Hide
Range on Protein: 75-357
Range on HMM: 9-256/258
Sequence Identity: 16% (47 aa)

TSAMTYPN-TYDKFLNNMDMNRIPHLYCFDHSRVelAPQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDHTeYIFWRMVSERKP-SMILVFGDIDEKQKR
..... .. | ..| .|...|| ..  . |..||   ..|..|...|||...  . .  .|..| |  | .   |||||.. ||..|...| . |...  
laslkpnketckafeknlkknrskdvkilDetrV--kltdeddsYinaskiklddlekkliltQlPlpdte-edFWrmvyqekitsvvllvedeelketa

KapydisdrgfeksflhefgaksleecelkakicrKFWP-EKRSKKDFPTLSIQASDDHSETHM-KTFNLTVTEKKQDHQTV--LMHFYEWADASKLPey
                                 .|.| |. . . . .. |.     ..... | ... |  ...  ...  . |. .| . . ..    
v----------------------------------sffpletgdylnlgkmfinnrkvevkedekkeytvevlpegcsesvfakvyhlttWkkkkvPd--

mlDMRASIKLQYIRSSKKTGVCIGPIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
.  . ||..  . ..|. ..  |...|. .|... .  .......  ....  . ..|.. .|. || | . ..  |... ......  
--kvkkvikraiekvlskkqgknapvvvvsdlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavldy

Phosphatase M05D6.3.AA Subfamily.RG.PD 85-174 38 2e-21 67.5 In-house 22-112 (264) Show / Hide
Range on Protein: 85-174
Range on HMM: 22-112/264
Sequence Identity: 38% (35 aa)

DKFLNNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFNdHTEYIFWRMVSERKPSMILVFGDIDEKQKRKA
|  .|   ||  ..  ...|||.|.|  |||  |. |||..||| .. .|| .| | . .|   ||||. |.. ..| .  |.|||..|.  
skkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplk-etiedFWrmiWehnaqiivmltdldekgrrde

Phosphatase M05D6.3.AA Subfamily.R_Sponge_2.PD 86-174 38 2.5e-21 67.2 In-house 21-109 (262) Show / Hide
Range on Protein: 86-174
Range on HMM: 21-109/262
Sequence Identity: 38% (35 aa)

KFLNNMDMNRIPHLYCFDHSRVELAP-QDGKDDFYNASWVDGYSKKSAYIFAQAPFNDHTEyIFWRMVSERKPSMILVFGDIDEKQKRKA
|  .|.  || .  . .|.|||.| . .  . |. |||.|||| ...||| .|.|...  |  ||||| | | |.|... .. |..| |.
klkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrrkayiatqgPlketve-DfWRmvweykvstivmltnleengkekc

Phosphatase M05D6.3.AA Subfamily.RA.PD 89-174 35 1.4e-19 61.4 In-house 26-112 (266) Show / Hide
Range on Protein: 89-174
Range on HMM: 26-112/266
Sequence Identity: 35% (31 aa)

NNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFNdHTEYIFWRMVSERKPSMILVFGDIDEKQKRKA
.|.. ||. ..  .|.||| |. ..|..  |. |||..||| .|  .| || | . .|   ||||. |.| . |... ...|... | 
enkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpke-etvedfwrmiweqksativmltelkerkeekc

Phosphatase M05D6.3.AA Subfamily.R_Ecdysozoa.PD 88-176 35 5.1e-19 59.4 In-house 26-114 (269) Show / Hide
Range on Protein: 88-176
Range on HMM: 26-114/269
Sequence Identity: 35% (32 aa)

LNNMdMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFnDHTEYIFWRMVSERKPSMILVFGDIDEKQKRKAPY
|..  || ...  ||. || |..  ||.  |. |||.. || .|  .| ||.|  . |   ||||..|..  .| .  ...||... | | 
enal-knryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPv-eatigDfWrmiaeqevtlivmlsnlteknrkcaky

Phosphatase M05D6.3.AA Subfamily.R_Anemone_2.PD 89-174 37 2.2e-18 57.7 In-house 26-112 (262) Show / Hide
Range on Protein: 89-174
Range on HMM: 26-112/262
Sequence Identity: 37% (32 aa)

NNMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKKSAYIFAQAPFNDHTEyIFWRMVSERKPSMILVFGDIDEKQKRKA
|   ||   .  .|..||.| ...|.   |. ||...||| .| ||| .|||  .  |  ||||| |.. ..|..  .. |. |.|  
vnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetie-dfWrmvWeqnsavivmltqeeergkakv

Phosphatase M05D6.3.AA Subfamily.N9.PD 84-174 35 4.1e-18 56.7 In-house 20-111 (275) Show / Hide
Range on Protein: 84-174
Range on HMM: 20-111/275
Sequence Identity: 35% (33 aa)

YDKFLNNMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKKSAYIFAQAPFNdHTEYIFWRMVSERKPSMILVFGDIDEKQKRKA
. |   |.. ||   . |.|..|| || .|..   |. ||..|||| .| |.| .| |.. .|   ||||| |..  .|..   . |....| 
asklranleknrytdvlcydetrvklakldedeasdyinanfvdGykqkkafiatqGplk-ktvsdfwrmvweqevlvivmttrvvergrlkc

Phosphatase M05D6.3.AA Subfamily.R_Anemone_1.PD 86-174 34 5.9e-17 53.1 In-house 21-110 (258) Show / Hide
Range on Protein: 86-174
Range on HMM: 21-110/258
Sequence Identity: 34% (31 aa)

KFLNNMDMNRIPHLYCFDHSRVELAP--QDGKDDFYNASWVDGYSKKSAYIFAQAPFNDHTEyIFWRMVSERKPSMILVFGDIDEKQKRKA
.  .| . ||  ..  .||||| |    .| . |. |||......|. |.| .|||... .|  ||||| . | . | .  .. |..|.| 
rkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetve-dFWrmvwqekigviVmLtnliegekkkc

Phosphatase M05D6.3.AA Subfamily.N_Nematode_6.PD 84-348 23 6.4e-17 52.7 In-house 18-242 (253) Show / Hide
Range on Protein: 84-348
Range on HMM: 18-242/253
Sequence Identity: 23% (61 aa)

YDKFLNNMDMNRIPHLYCFDHSRVELApqdGKDDFY-NASWVDGYSKKSAYIFAQAPFNDHTEyIFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDR-
||.. |.|| . . |.| .|..||   . .|||  |. |.  .|.  .| .|||...  |  ||.|.      .|... ..|| | |.   .||. |   
ataflkfkdrnrytniqCcdagrlkla---ddedfyihanlvkistkprrlictqaplegtie-efwkmilssgveyivmlcelvekgkeksaeylsdkv

GfeksflhefgaksleecelkakicrkfwpEKRSKKDFPT-LSIQASDDHSETHMKTFNLtVTEKKQDHQTVLMHFYEWADASkLPEYMLdmRASIKLQY
                          ..|   .. | . |. .|    ... .  . | . ....|. .| |   .|. .|   |   |. ....||   
G-----------------------------darkitklctvikigrkdidkilvrslkri-vkagdeevivkhihWanWPdhG-vPdsfl--salrllsv

IRSSKKtgvcigPIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYS
   ||.. |..|| .    | | ||.  .   .  | |. ... .|| . .|.  |            
vkkdkk------PivvhCsaGvGrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqyl

Phosphatase M05D6.3.AA Subfamily.N_Choan_1.PD 87-165 32 1.2e-16 51.9 In-house 23-102 (262) Show / Hide
Range on Protein: 87-165
Range on HMM: 23-102/262
Sequence Identity: 32% (25 aa)

FLNNMDMNRIPHLYCFDHSRVELAPQ--DGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYIFWRMVSERKPSMILVFGD
.|.  ||   .  .|..||...|.  . . |. ||..|.||... .|| .|.|  . . ..||.|| |.| |.| .     
adenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPa-slvsfWqmvweqkvsaivmvtr

Phosphatase M05D6.3.AA Subfamily.RB.PD 85-174 35 5.6e-16 49.6 In-house 21-111 (261) Show / Hide
Range on Protein: 85-174
Range on HMM: 21-111/261
Sequence Identity: 35% (32 aa)

DKFLNNMDMNRIPHLYCFDHSRVELAPQ--DGKDDFYNASWVDGYSKKSAYIFAQAPFNDHTEyIFWRMVSERKPSMILVFGDIDEKQKRKA
.   | . ||  ..  .|||||.||    . ..|. ||....||...  || .| |... ..  ||||| |.| |.|...  . || | |  
aeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvd-dfWrmvwekkssiivmltqlvEkgkekc

Phosphatase M05D6.3.AA Subfamily.RK.PD 88-172 30 9.6e-16 48.6 In-house 27-111 (267) Show / Hide
Range on Protein: 88-172
Range on HMM: 27-111/267
Sequence Identity: 30% (26 aa)

LNNMDMNRIPHLYCFDHSRVELAPQDGK-DDFYNASWVDGYSKKSAYIFAQAPFNDhTEYIFWRMVSERKPSMILVFGDIDEKQKR
.| . ||. ..  .|.|.| | . ||   |. ||...|.| . .|.| .| | .. | . |||.| . . . |..  ..| .. | 
drnreknrsmdilaydrslvflisvdgdssdyinaalidsykrpaafivtqgPlqe-tvkdfWrlvydencasivmlteldvevgr

Phosphatase M05D6.3.AA Subfamily.R_Anemone_1.PD 200-349 21 2.2e-15 48.0 In-house 104-248 (258) Show / Hide
Range on Protein: 200-349
Range on HMM: 104-248/258
Sequence Identity: 21% (32 aa)

ELKAKICRKFWPEKRSKKDFPTLSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYM---LDMRASIKLQyirssKKTGVciGPIML
| . | | ..||.. .| .  ..|.. ... ..  ..|. |. ........ | .|| .|.| .  |.|.   |..| ... ....|    |... |. |
egekkkchqYwPdstekygelrvslrkkevfadyiirtlvlskkketeerevvqyhftvWpdkg-vPqyatavLglrrkvqks-----slaga--rpvvv

VCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYST
|..  .   || .. .. .|. |   ... ||. .|    .|   |.      
hCsaGvgRtGaflvidamleqakkekvvDifnyvkairedrphmvqtkeqyvf

Phosphatase M05D6.3.AA Subfamily.N_Nematode_4.PD 78-195 26 2.8e-15 47.3 In-house 14-126 (264) Show / Hide
Range on Protein: 78-195
Range on HMM: 14-126/264
Sequence Identity: 26% (31 aa)

MTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKDDFYNASWVDGYsKKSAYIFAQAPFNDhTEYIFWRMVSERKPSMILVFGDIDEKQKRKAPYD
.    |.. . .|.| ||  ...| |..|| |  .| . |.  |||.     |. || .| |... |   || || . | ...... |  |.. .|    
appnvtasaseknsdknryadilcidetrvvlknrdpdndyihaswmrmP-dkfryistqGPlke-tlsdfwhmvytekiavvvmlcdlieegvekcary

ISDRGFEksfLHEFGAKS
....  .    ..||   
ypeksek---vvkfGkyr

Phosphatase M05D6.3.AA Subfamily.R_Ecdysozoa.PD 200-348 21 6.5e-15 45.9 In-house 106-258 (269) Show / Hide
Range on Protein: 200-348
Range on HMM: 106-258/269
Sequence Identity: 21% (33 aa)

ELKAKiCRKFWPEKrSKKDFPTLSIQASDDHSETHMKTFNLTVTEKK----QDHQT-VLMHFYEWADASKLPEYMLDMRASIK-LQYIRSSKKTGVCIGP
| . | | |.||.   .. .  . ..  . .. ..    .|.|..||    .|..  |  .. .|   || ||    .   |. .. . . .|   . .|
eknrk-cakyWpie-devqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsP

IMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYS
|.. | .||.. .|  ..|... .. .|..|   ||.  .. ||   .. .  |.
ivvhCsaGvgrsgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyv

Phosphatase M05D6.3.AA Subfamily.N3.PD 204-356 16 9.8e-15 45.4 In-house 109-258 (261) Show / Hide
Range on Protein: 204-356
Range on HMM: 109-258/261
Sequence Identity: 16% (26 aa)

KICRKFWPEKRSKKDFPTLSIQASDDHSETHMKTFNLTVTEKK--QDHQTVLMHFYEWADAsKLPEYMLDMRASIklQYIRSSKKtgVCIGPIMLVCATG
. | ..|||.  . .| ..|.. . ..... . . .|....|.  .... . . . .|.|  ..|.   |.   .  . .|. ..  .   |... |..|
vkChqyWPetedelefgefsvrcekedetksyvlrelvlkdketkeerkilqlqylaWpdh-gvPddsadflefv--ervrklrs--gkeePvvvhCsaG

VEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
...  .  .... .. | ... |   . .. .. ||    .||. |   || ..|
igrtGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvCeailk

Phosphatase M05D6.3.AA PTPc_motif 250-356 20 1.6e-14 55.45 SMART 1-92 (92) Show / Hide
Range on Protein: 250-356
Range on HMM: 1-92/92
Sequence Identity: 20% (23 aa)

QTVLMHFYEWADA----SKLPEYMLDMRASIKLQYIRSSKKTGVCIGPIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVG
.   .|.. | |     |..||       .  |..||. .|      ||. .|  |.  ..  ..||.....      | ...|. ....|| | . |  
TVHHYHYTNWPDHVEKDSGVPE-------DSILEFIRHVRK------PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEE

PYSTACEMLMK
 |   ......
QYIFCYRCILE

Phosphatase M05D6.3.AA Subfamily.N12.PD 77-174 30 1.7e-14 44.5 In-house 19-117 (270) Show / Hide
Range on Protein: 77-174
Range on HMM: 19-117/270
Sequence Identity: 30% (29 aa)

AMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFNdHTEYIFWRMVSERKPSMILVFGDIDEKQKRKA
.|...  .  .|.  ||   .  .|.|||||  .....  |. ||... | ..| .|| ||.|.  .|   ||||. | . .....   .| .| |    
ekvysteagekeenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLp-ktlddfWrmiweknveivvmaCrevelgkkkC





Phosphatase M05D6.3.AA Subfamily.N1.PD 73-174 30 2.5e-14 44.3 In-house 9-109 (268) Show / Hide
Range on Protein: 73-174
Range on HMM: 9-109/268
Sequence Identity: 30% (30 aa)

MHTSAMT--YPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGkdDFYNASWVDGYSKKSAYIFAQAPFNdHTEYIFWRMVSERKPSMILVFGDIDEKQ
... . .  ..... |. .| ..||   .  .||||..|  .|   |. ||| |.    |  || .| |   ||   ||.|| |..   .... ||.. |
idkeskekeletreaklpenrglnryrdvspydhsrikleradv--dyinaslveleeakrrYiLtqGPLp-htadHFWqmvWeqnskavimLnkvvEkn

KRKA
    
qikC

Phosphatase M05D6.3.AA Subfamily.RB.PD 204-357 16 2.5e-14 44.2 In-house 109-259 (261) Show / Hide
Range on Protein: 204-357
Range on HMM: 109-259/261
Sequence Identity: 16% (25 aa)

KICRKFWPEKRSKKDFPTLSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYMLDMRASIKlqYIRSSKKTGVCIGPIMLVCATGVE
. | ..||.....  .  ....   ......  . .......|. ..   .||  |.| .  ||    . . ..   .|.. .. .  .||.|. || . 
ekceeYWPadeepvlyGdikvtllaekeldewvirefkiekgkekrkvrqyhftsWpdhg-vPektktlldfvr--tvreaiekkaskkPivvHCsaGvG

KCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
 .  ..| .. .|.|.  |    ... ....|     |   |    |.|...  
RtGtfialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl

Phosphatase M05D6.3.AA Subfamily.N9.PD 202-358 22 6.2e-14 43.0 In-house 107-274 (275) Show / Hide
Range on Protein: 202-358
Range on HMM: 107-274/275
Sequence Identity: 22% (37 aa)

KAKICRKFWP-EKRSKKDFPTLSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHF--YEWADAS--KLPEYMLDMRASIKLQ------YIRSSkKTGVC
.   |...|| |. |...| .||..  ....| . |. .|.... |....  ..||    | |    .  . .||..  .. .      .. ....| . 
grlkcgqywpleeessaefgdlsvsnveveveedykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgde-skghl

IG-PIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFA
| ||.. |..|. .    .|.|| ..|. |.  |  .||.. .. ||    .|   |      .. .| 
sgPPivvhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya

Phosphatase M05D6.3.AA Subfamily.N6.PD 198-355 19 7.7e-14 42.6 In-house 131-291 (295) Show / Hide
Range on Protein: 198-355
Range on HMM: 131-291/295
Sequence Identity: 19% (31 aa)

ECELKAKICRKFWPEKRSKKDFPTLSIQASDDHSETHMKTFNLTV--TEKKQDHQT-VLMHFYEWADAS--KLPEYMLDMRASIKLQYIRSskktgVCIG
| |   . | ..||....||.. .....  ...|... .  ...|   .|...... . .||  | |..  | |. .|..   .. .. .|||.. |..|
evergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdkeareifqyhfkaWPdhgvpkdpgvvlnfledvnkkqeel-----ekag

PIMLVCATGVEKCAISATIDIIVSRITEE---HRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLM
. .      |||... |...     . .....  ...|| |   |   |     ...         
pivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvykavq

Phosphatase M05D6.3.AA Subfamily.N14.PD 87-175 30 1.1e-13 42.0 In-house 23-113 (275) Show / Hide
Range on Protein: 87-175
Range on HMM: 23-113/275
Sequence Identity: 30% (27 aa)

FLNNMDMNRIPHLYCFDHSRVELAPQ-DGKDDFYNASWVDG--YSKKSAYIFAQAPFnDHTEYIFWRMVSERKPSMILVFGDIDEKQKRKAP
.| . ||....  ....||||.|. . .... ||| .     .|.  || ||.|  ..|  .||.|| |.. ..|.   ...|. | |.   
lpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPl-eltvqdfwqmvweqgvqlivmlteeeedgkeksf

Phosphatase M05D6.3.AA Subfamily.R_Anemone_2.PD 202-349 25 1.3e-13 42.1 In-house 109-252 (262) Show / Hide
Range on Protein: 202-349
Range on HMM: 109-252/262
Sequence Identity: 25% (38 aa)

KAKiCRKFWPEKRSKkDFPTLSIQASDDH--SETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKlPEYMldmraSIKLQYIRSSKKTG--VCIGPIMLV
||| . ..||.| |.  . .| ......   |.  ...|... ||.... |    |. .|.| .  ||       .  |. .|...|.      |||.. 
kak-vhryWPskgsr-sygklvvelkeevelsdyvlrsfkvkrteeeeerqvrqfhytsWpdegv-pesg-----aslldlvrqvekaqqesgagpivvh

CATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYST
|..|| .  .  ..||.. || .|  |   .|.. .. ||    .|   |  
csaGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyef

Phosphatase M05D6.3.AA Subfamily.R_Nematode_2.PD 87-339 20 1.6e-13 41.5 In-house 26-241 (261) Show / Hide
Range on Protein: 87-339
Range on HMM: 26-241/261
Sequence Identity: 20% (45 aa)

FLNNMDMNRIPHLYCFDHSRVELAPQDGKDDfYNASWVDGYSKKSAYIFAQAPFNDhTEYIFWRMVSERKPSMILVFGDIDEKqkrkapydisdrgfeks
.  . | .| |.. | ....||   .. . .   | ||.  ...  .| .|.|... | . || ||   |   |....   ||. ..| ...| .  .| 
aylpkdkhRypdvPCkpetavevivdgkrvp-ihanwvptagnpkrfiatqgPlen-tsedfWamviqekvekivmlcqkvek-----------------

flhefgaksleecelKAKICRKFWPEKR-SKKDFPTLSIQASDDH----SETHMKTFNLTVTEKKQDHQTVLMH-FYEWADaSKLPEYMLDMRasIKLQY
|. ..||.  . .     |.. .|.. . ...| ..||  . . ||.|   .|.  ...     |. .. |.|      ||.  |..|. .     ... 
---------------ekekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatrtvthyqyeeWpd-rgvPkshaelf--eLlel

IRSSKKtgvcigPIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFG
. ... ... . ..|.... .|                                     
vkksek------PivvhCsaGiGRtmafigteylareveadptieltealkelrehRwk

Phosphatase M05D6.3.AA Subfamily.RG.PD 203-354 18 6.1e-13 39.7 In-house 109-259 (264) Show / Hide
Range on Protein: 203-354
Range on HMM: 109-259/264
Sequence Identity: 18% (29 aa)

AKICRKFWPEKRSKKDFPTLSI--QASDDHSETHMKTFNLTVTEKKQDHQ--TVLMHFYEWADASKlPEYMLDMRASIKLQyirsSKKTGVCIGPIMLVC
.. . ..||.|    .. .|..   . . .|.  ...| |  |.......      |. .| | .  ||..|..  ..| .    .. .    |||....
rrdedvyWPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgs-Pestlfvlifvkke----eaankeeaGPivvhd

ATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEML
 .|| . ..   .| .. .. .|. |   ...  |...| | . |   |    ..|
saGvgragtyialdtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydal

Phosphatase M05D6.3.AA Subfamily.N_Nematode_1.PD 79-338 22 1.3e-12 38.5 In-house 13-244 (265) Show / Hide
Range on Protein: 79-338
Range on HMM: 13-244/265
Sequence Identity: 22% (59 aa)

TYPNTYDKFLNNMD--MNRIPHLYCFDHSRVELAPQDGKDDFYNASWVDGYSKKSAYIFAQAPFnDHTEYIFWRMVSERKPSMILVFGDIDEKQKRKAPY
. ... . | .. .   ||   . | |..|| || .    |.  | .|   ..   .| ||||  |.| . || ||   |  .|... .. || |.|   
ndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnpkrficaqaPl-dktiadfwymvlqekveaivmlckliekgkkkcae

DISDRGFEKSFLhefgakslEECELKAKIcrkfwpEKRSKKDFptlsiqASDDhsETHMKTFNLTVTEK-KQDHQTVLMHFYEWADASkLPEymLDMRAS
  . .  ||  .        .| . |  .      |. .. ..       ..|  |  .|. .|.|... ...  ... .| |    |.   |. |   |
yfpakegeklef--------kekgqkitv------enslgvkk------leed--eevikvtvlevegaGektrkvthyqWtdWPdrG-vPp--adlaal

IKLQYIRSSKktgvciGPIMLVCATGVEKCAISATIDIIVSRITEEHRVG-FKETMSAIKMQRF
. .|.||      |||.. |..|. .     .|. |. .. |...... . .|. ||       
elleavrgsk------gPivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrn

Phosphatase M05D6.3.AA Subfamily.N_Choan_2.PD 87-173 30 2.7e-12 37.3 In-house 18-106 (266) Show / Hide
Range on Protein: 87-173
Range on HMM: 18-106/266
Sequence Identity: 30% (27 aa)

FLNNMDMNRIPHLYCFDHSRVELAPQ--DGKDDFYNASWVDGYSK-KSAYIFAQAPFnDHTEYIFWRMVSERKPSMILVFGDIDEKQKRK
. .|  .||   .    ..|| |..   | .  ..|| .| |... | .|| |..|  . |   ||||. |.| . |..  .. ||..| 
yarnkrlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPl-pttlksfwrmiweekvtaivmttgleEkgrkk

Phosphatase M05D6.3.AA Subfamily.R_Sponge_2.PD 201-353 19 2.8e-12 37.6 In-house 104-256 (262) Show / Hide
Range on Protein: 201-353
Range on HMM: 104-256/262
Sequence Identity: 19% (30 aa)

LKAKICRKFWPEK-RSKKDFPTLSIQA--SDDHSETHMKTFNLTVTEKKQDHQTV-LMHFYEWADASKlPEYMLDMRASIKlQYIRSSKKTGVciGPIML
. . | |.||||   ......  ..   .   ..  .....|. .........|   || .|.. .. |..   . . || .  |. ||.|   ..|..|
ngkekcakYWPekvdeeveygkfkvtlkeeekladyiirklklskekssegeadvtqfhfvaWpehev-Pkdatsllelik-rvlraqkksgn--kaitv

VCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEM
|  || .     ..|....|. .|. .   |..  ....| |  ...  |    .. 
vCsdgvgrtGtfialdsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihda

Phosphatase M05D6.3.AA Subfamily.N_Choan_2.PD 203-357 17 9.8e-12 35.5 In-house 104-264 (266) Show / Hide
Range on Protein: 203-357
Range on HMM: 104-264/266
Sequence Identity: 17% (28 aa)

AKICRKFWPEKRSKK-DFPT--LSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKLPEYMLDMRASIK---LQYIRSSKKTGVCIGPIML
| | ..||... .| .. .  ... |. .. |.   . .|....|.. .. |  ....| | .   |    ....     |. .|..|     .|..  |
rkkCerYWpaepkekvkladgkikvlalseekeegyiltrlrlekkgetrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllv

VCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
. ||..  .  .|||.|  . |...|   . ..... .|  . ...  |  . . ....  
HcsaGvgRtGtliaiDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyellykavvey

Phosphatase M05D6.3.AA Subfamily.N13.PD 204-347 19 3.5e-11 34.0 In-house 106-247 (259) Show / Hide
Range on Protein: 204-347
Range on HMM: 106-247/259
Sequence Identity: 19% (29 aa)

KICRKFWPEKRSKKDFPT--LSI--QASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYMLDMrasikLQYIRSSKKTGVCIGPIMLVCA
|...|||...||   .  | .      ....  ....... .| .. .. . ..| .| | .  |    ..     .|...  ..     |||.  |..|
vkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhg-vPssaael-----vqfvaevrllqtdagPivvhcs

TGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPY
. .  .  |||...  |  .. .  ||..  .. || |  .|   |  
aGiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqy

Phosphatase M05D6.3.AA Subfamily.N3.PD 86-173 27 5.1e-11 33.2 In-house 22-110 (261) Show / Hide
Range on Protein: 86-173
Range on HMM: 22-110/261
Sequence Identity: 27% (25 aa)

KFLNNMDMNRIPHLYCFDHSRVELApqDGKDDFYNASWVD----GYSKKSAYIFAQAPFNdHTEYIFWRMVSERKPSMILVFGDIDEKQKRK
.  .|.. ||   .  .|. ||.|   ... |. ||..|.    . .    || .| |.. .|   ||.|| |.| ..|... .. |. . |
rkpenlaknryrdilpydatrvklk--esetdyinanyvnmeipstglvnryiatqGpla-ktakdfWqmvweqkstlivmlttlverGrvk

Phosphatase M05D6.3.AA Subfamily.N_Nematode_eak.PD 87-354 19 5.5e-11 33.2 In-house 23-276 (281) Show / Hide
Range on Protein: 87-354
Range on HMM: 23-276/281
Sequence Identity: 19% (52 aa)

FLNNMDMNRIPHLYCFDHSRVELAPQD-GKDDFYNASWVDGYSKKSAYIFAQAPFNDHTeYIFWRMVSERK-PSMILVFGDIDEKQKRKAPYdISDRGfE
|.... ||. ..  .|.  |.|..    .| . ||| ..       ||.. .. .|.  ..||.|| |.| |... .  |..|| ..   |   |.. |.
rleavnrnrvvkivpqdrylvrltssqlnrdGyinaslaefsevGrkyiltGiasedkv-fafwqmvleqkspaivqlledveekleksdky-fpdkt-e

KsflHEFGAKSLEecelkakicRKFWPEKRSKKDFPTLSIQA-SDDHSETHMKTFNLTvtEKKQDHQTVLMHFYEWADASKLPeYMLDMRASIKLQYIRS
    ..|   .|         || .  ||.. ..  | ..   . |   | | |  |  | ... ...       .  .. |....   ...  ..|  .
v---lkyGildve---------rkeyavkrniletrllilrkGnethrvlhykvfGwt--ettlpkyedflalrkvmkevGvl-llivmksallrstlkk

SKKTGVCIGPIMlVCATGVEKCAISATIDIIVSRITEEHRVGF--KETMSAIKMQRFGCFRTVGPYSTACEML
  ||.  .|.|  .. .   ||...  | .  .  .  .. .  .| .|  .  .   .|   |..       
yihtppsfapii-qsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeiv

Phosphatase M05D6.3.AA Subfamily.N_Nematode_egg.PD 88-216 25 8.2e-11 32.7 In-house 24-119 (257) Show / Hide
Range on Protein: 88-216
Range on HMM: 24-119/257
Sequence Identity: 25% (32 aa)

LNNMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKKSAYIFAQAPFNDhTEYIFWRMVSERKPSMILVFGDIDEKqkrkapydisdrgfek
|...  | ... | . |||.|  . |.  |||  |  |.|      .| ||||. . |   ||||| . |   |...|                      
dnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkn-tvedfwrmvfqekvqyivmltsakes----------------

sflhefgaksleecelkaKICRKFWPEKRSK
             . |  .||   |.     
------------------erceyywpkaese

Phosphatase M05D6.3.AA Subfamily.N5_RR.PD 88-174 26 1.4e-10 31.9 In-house 21-110 (265) Show / Hide
Range on Protein: 88-174
Range on HMM: 21-110/265
Sequence Identity: 26% (23 aa)

LNNMDMNRIPHLYCFDHSRVELAPQDGKDD---FYNASWVDGYSKK-SAYIFAQAPFNdHTEYIFWRMVSERKPSMILVFGDIDEKQKRKA
.   ||   .   ..||| | .....|.   . || .. ||...  ||. .| |.  .|   ||||. ... ..|..  .. |....|   
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlp-ntiadfWrmiyqeevqvivmltklkeanrqkc

Phosphatase M05D6.3.AA Subfamily.N_Choan_1.PD 205-345 15 1.5e-10 31.9 In-house 110-248 (262) Show / Hide
Range on Protein: 205-345
Range on HMM: 110-248/262
Sequence Identity: 15% (22 aa)

ICRKFWPEKRSKKDFPTLSIQASDDHSETHM--KTFNLtVTEKKQDHQTVLMHFYEWADA--SKLPEYMLDMRASIKlQYIRSSKKtgvciGPIMLVCAT
| ..||...|.  . .. ..    ......  ..|.|  .|. .  . . ...  | |    . .. .|. |. .. .. ....||... |..|| .   
kChryWPdenselklgdvtvkslseeekktyierkfkl-eresgetreveqlaytaWPdhGvPattkellefrkavl-katkkktk-----aplvihCsa

GVEKCAISATIDIIVSRITEEHRV-GFKETMSAIKMQRFGCFRTVG
  ..| .|....|.. .   |.... .. .|    .|.        
GvGrtGtyialDrlvkaveekaealdvkavvaelrkernlmvqtlv

Phosphatase M05D6.3.AA Subfamily.N5_RR.PD 200-356 15 1.7e-10 31.6 In-house 104-262 (265) Show / Hide
Range on Protein: 200-356
Range on HMM: 104-262/265
Sequence Identity: 15% (25 aa)

ELKAKICRKFWPEKRSK---KDFPTLSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMH-FYEWADASK--LPEYMLDMRASIklqyIRSSKKTGVCIGP
| . . | ...|....    . .  ..|. ..  .. . .  .|...  .. ...|  . . .| |      .. .||. . .     .|...   ..|.
eanrqkcavyfPdaedyeiserygdveikveeiverndysvrklvlkylerversvkhywytdWPdhksPddintlldlvlev----eesreeenaklaP

IMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
.. |..|. .  .  .|.| | .. ||. |   .... ....| |  .|   |    ..|.. 
vvvhcsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl

Phosphatase M05D6.3.AA Subfamily.N23.PD 198-323 19 2.5e-10 30.8 In-house 181-313 (350) Show / Hide
Range on Protein: 198-323
Range on HMM: 181-313/350
Sequence Identity: 19% (25 aa)

ECELKAKICRKFWPEKRSK-KDFPTLSIQASDDHSETHMK--TFNLTVTEKKQDHQTVLMHFYEWAD--ASKLPEYMLDMRASIKLQY--IRSSKKTGVC
| | . . | ..||... . . |. |..  .. .|  ..   ...|. .. .. .. . .|. .|..  . | || .|..   ..  |   |..  |   
evegnklkcdqYwPidegetnlfgdlrvslkslrssegwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeg

IGPIMLVCATGVEKCAISATIDIIVSRITEEHR
 ||.| | .||..  . . .  ..  .|...  
gkPiilhCsaGvgRtgtfcvvysaireltagng

Phosphatase M05D6.3.AA Subfamily.RN.PD 89-183 32 3e-10 30.7 In-house 26-122 (264) Show / Hide
Range on Protein: 89-183
Range on HMM: 26-122/264
Sequence Identity: 32% (30 aa)

NNMDMNRIPHLYCFDHSRVELAPQ--DGKDDFYNASWV-DGYSKKSAYIFAQAPFNdHTEYIFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDRGF
.|.. ||  ..  .|||||.|  .  . |.|. ||| . |   ...||| .|.| . .|   ||.|| |.   .|. .  ..|.. ..| |       
knvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgpls-stiadfwqmvweqGvvvivnltrleeegvkqckrywpdeGs

Phosphatase M05D6.3.AA Subfamily.RC.PD 112-173 36 8e-10 29.3 In-house 69-129 (288) Show / Hide
Range on Protein: 112-173
Range on HMM: 69-129/288
Sequence Identity: 36% (22 aa)

QDGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYIFWRMVSERKPSMILVFGDIDEKQKRK
.   .. |||..|.| |   || || | .. |   ||||. |||  .|..  ...| .. | 
seegskyinasfidsykkpekyiaaqGplke-tvddfwrmiferkvkvivmltelkeGdrek

Phosphatase M05D6.3.AA Subfamily.N12.PD 198-322 21 1.1e-09 28.7 In-house 109-230 (270) Show / Hide
Range on Protein: 198-322
Range on HMM: 109-230/270
Sequence Identity: 21% (26 aa)

ECELKAKICRKFWPEKRSKKD-FPTLSIQASDDHSET-HMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYMLDMRASIKLqyIRSSKKtgVCIGPIM
| ||. | |...|||.  ..  | ..... ....  .  .    |.|. .|. ..   .|. .| |    |. . .. . |.|  .|. ..|... |. |
evelgkkkCeryWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhytaWPDhg-vPssakslleliel--vrelqe--sedaPlv

LVCATGVEKCAISATIDIIVSRITEEH
| .  .  .||.. . . .|.      
vhCsaGvGrtGtiiaidyvrellkaek

Phosphatase M05D6.3.AA Subfamily.N14.PD 203-357 15 1.2e-09 28.7 In-house 109-273 (275) Show / Hide
Range on Protein: 203-357
Range on HMM: 109-273/275
Sequence Identity: 15% (26 aa)

AKICRKFWPEKRSK---KDFPTLSIQASDDHSETHMKTFNLTVT--EKKQDHQTVLMHFYEWADASkLPEY------MLDMRASIKLQYIRSSKKTGVCI
. . |..|.. ||    .|    ...   .. . . | .|..     |.. . . . . .|.|   .||        |..  |.. .  .... .     
keksfkylPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhg-vPeDvkgflsfLeevqsvrrktnsevesvkesk

GPIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
|... |. || .  .  . |.... . .....  |.... .. ||    .|.. |    ..|.|. 
PPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvliky

Phosphatase M05D6.3.AA Subfamily.RC.PD 203-349 15 1.4e-09 28.5 In-house 127-278 (288) Show / Hide
Range on Protein: 203-349
Range on HMM: 127-278/288
Sequence Identity: 15% (22 aa)

AKICRKFWPEkrSKKDFPT--LSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADAS--KLPEYMLDMRASIK--LQYI-RSSKKTGVCIGPIM
..| ..| |   |. .    . ..  |  |.  .. ..|    .|.  . . . . .|..    . |. .|..   .|  |    .|.|... |  |...
rekcaeywee--GkrayGdvevdlkdtdkssdyilrklelvnkkrkdsrevtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpll

LVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYST
  |  ... ..  .  |..|   . . ... .| .  ..   |           
vhcrdGsqrtGifiallallesleaeekvdvfqvvkklrkarplmvsveeqyil

Phosphatase M05D6.3.AA Subfamily.RA.PD 200-356 19 2.5e-09 27.8 In-house 106-263 (266) Show / Hide
Range on Protein: 200-356
Range on HMM: 106-263/266
Sequence Identity: 19% (31 aa)

ELKAKICRKFWPEKRSKkDFPTLSIQASDDH--SETHMKTFNLT----VTEKKQDHQTVLMHFYEWADAS--KLPEYMLDMRASIKLQYIRSSKktgvci
| | . | ..||.. .   .  . ..  |.    .  .. | .|     |..|.  .   .||  | .      .  ||.. . .| .  .|..||.. |
erkeekcaqywpdeGlv-tyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsan------

GPIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
..|| .     ..| .. |.  |...   |... ...||    .|   |    ..|..       
hpivvhcsaGvGrtGtfivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvlle

Phosphatase M05D6.3.AA Subfamily.RK.PD 202-339 19 8.7e-09 25.8 In-house 110-247 (267) Show / Hide
Range on Protein: 202-339
Range on HMM: 110-247/267
Sequence Identity: 19% (26 aa)

KAKICRKFWPEKRSK--KDFPTLSIQaSDDHSETHMKTFNLTVTEKKQDHQTV--LMHFYEWADASKLPEYMLDMrasikLQYIRSSKKTG--VCIGPIM
.  | |.|||. ..  .|.    .. .. ...  ...|...   ..|. . .   ..|  |..  . |..   .     |..||  ||.|.|.. | .| 
grvkClkyWPedtevrygdikvelve-aeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsl-----lklirrvkksqeeeeeGriv

LVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFG
 .  .  .|||..  | .|. |   ... ... ..         
vhClaGaGrsGtfiaidivlemieregvvdvfnavktlrnrkvn

Phosphatase M05D6.3.AA Subfamily.N23.PD 103-173 32 1.3e-08 25.2 In-house 115-188 (350) Show / Hide
Range on Protein: 103-173
Range on HMM: 115-188/350
Sequence Identity: 32% (24 aa)

DHSRVELA--PQ-DGKDDFYNASWVDGYSKKS-AYIFAQAPFNdHTEYIFWRMVSERKPSMILVFGDIDEKQKRK
|..||.|   .|   .||..||...   .  |  .| .|.| .  |   || || |.. |.| .  .  |..| |
dpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPia-stlaDFWlmvweqqssviVmltkevegnklk

Phosphatase M05D6.3.AA Subfamily.N1.PD 202-343 17 2.7e-08 24.5 In-house 105-252 (268) Show / Hide
Range on Protein: 202-343
Range on HMM: 105-252/268
Sequence Identity: 17% (26 aa)

KAKICRKFWPEKRSK--KDFPT--LS--IQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADAS--KLPEYMLDMrasikLQYIRSSKKTGVCIGP
.   | ..||.....    . .  |.  . . ...|.  .....|.  |... .. .  |. .|.| .  ..| ..|..     |. .|.|.||....| 
nqikCaqywpqeeeeaellleetklkvkliseerksyflvrlleLedletqetreilhfhyttwpdfgvpespaafLkf-----LfkvresgsLssdvgp

IMLVCATGVEKCAISATIDIIVSRITEEHR---VGFKETMSAIKMQRFGCFRT
.|... .  . .| .. .| ..     |  |. . ... .| |   |      
avihCsagigrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqt

Phosphatase M05D6.3.AA Subfamily.R_Nematode_3.PD 196-356 17 3.4e-08 24.1 In-house 108-264 (267) Show / Hide
Range on Protein: 196-356
Range on HMM: 108-264/267
Sequence Identity: 17% (29 aa)

LEECELKAKICRKFWPEKRS-KKDFPTLSIQA--SDDHS--ETHMKTFNLTVTeKKQDHQTVLMHFYEWADAS--KLPEYMLDMrasikLQYIRSSKKtg
||.. . . | ...|||   .  |  .|..    . .   ..  .|. .|.  ||. ..   ...  | . .  . |...|........||.      |.
veedgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvvtfe-kkkeftvthllykgWkelnapeepkealel-----ikfvekskt--

vcigPIMLVCATGVEKCAISATIDIIVSRITEEH-RVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
.  | .|. . |  | |.. .  |....  . . . ..... || |.. |   .. .  ...|      
----pvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilk

Phosphatase M05D6.3.AA Subfamily.N_Nematode_4.PD 203-340 23 4.7e-08 23.6 In-house 105-245 (264) Show / Hide
Range on Protein: 203-340
Range on HMM: 105-245/264
Sequence Identity: 23% (34 aa)

AKICRKFWPEKRSK-KDFPTLSIQASDDHSE----THMKTFNLTVTEKKQDHQT--VLMHFYEWAD--ASKLPeymLDMRASIKLQ-YIRSSKKTgvciG
. | ...|||  | ..| .  |.  . . |    . ......|.||||.|  .  ........        |   || .. |||  ...  ||     .|
vekcaryypeksekvvkfGkyritlvekkeeviadvilnslkvtntekkkdapseplvvkhvqvdwwrdqvaP---ldaapviklykavkkkkke----k

PIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGC
|.. |..|| . |    ||.   ||.|   .   . .  ..  |..  
PivvhcsaGvGrtatlvGidyatirirenseievldivrelramrlka

Phosphatase M05D6.3.AA Subfamily.N13.PD 86-172 30 1.6e-07 22.1 In-house 22-106 (259) Show / Hide
Range on Protein: 86-172
Range on HMM: 22-106/259
Sequence Identity: 30% (27 aa)

KFLNNMDMNRIPHLYCFDHSRVELAPQDGkddFYNASWVDGYSK--KSAYIFAQAPFNDHTEyIFWRMVSERKPSMILVFGDIDEKQKR
|  .|.| ||  ..  .|..||.|  . |   . |||..       .  || .| |. . ..  ||.|| |.| ..| .     ||.| 
kkkenkdknryrnvlPydetrvklgdegg---yinaslikvpvgedeyeyiacqGPlPetvk-dfwqmvweqkaeviamvtlekekgkv

Phosphatase M05D6.3.AA Subfamily.N_Fungi_PTP1.PD 93-318 20 1.8e-07 21.4 In-house 48-287 (343) Show / Hide
Range on Protein: 93-318
Range on HMM: 48-287/343
Sequence Identity: 20% (49 aa)

MNRIPHLYCFDHSRVELA----PQDGK------DDFYNASWVDGY----SKKSAY--IFAQAPFNDhTEYIFWRMVSERKPSMILVFGDIDEKQKRKAPY
||   .  ..||||.|     . |.|      .|. ||...       . .. .  | .|||    |   |.... . |  .||   . .| . .|    
knrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlps-tvddfykvillnkvkvilsltsdvelnlekcyr

DISDRGFEKSFLHEfgaKSLEECELKAKICRKFWPEkrSKKDFPtLSIQASDDHSeTHMKTFNLTVTEKKQDHQTVL-MHFYEWADASKL--PEYMLDM-
  . ....  ..    .|  |    .. . ..  .   ||...    . |||   .   . . .||.  .|. ...  | | | |  || .| .   .  
YWqegsydditvkl---askwenimgindsslysad--vkkeas-dndnksddnd-lnnnndltpvtaavsepyevyqlqvknWkDlslllnPesilqal

--RASIKLQYIRSSKKTGVCIGPIMLVCATGVEKCAISATIDIIVSRI
.  . .  |        ||.  |. || .  .  |.| ..| .     
evkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdf

Phosphatase M05D6.3.AA Subfamily.N6.PD 77-173 27 7.2e-07 19.7 In-house 27-138 (295) Show / Hide
Range on Protein: 77-173
Range on HMM: 27-138/295
Sequence Identity: 27% (27 aa)

A---------MtypntydkfLNNMDMNRIPHLYCFDHSRVELAPQ--DGK-DDFYNASWV--------DGYSKKSA-----YIFAQAPFnDHTEYIFWRM
.| . ||      |||.|| |  .  . . .|. ||...        .| ...|      || .| .. ..|||||| . .  .|..     |. | |  
eklysrkegek---------ienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcL-kdtvsdFWrm

VSERKPSMILVFGDIDEKQKRK
                      
vwqensrvivmttkevergknk

Phosphatase M05D6.3.AA Subfamily.R_Nematode_3.PD 72-171 19 9.2e-07 19.4 In-house 5-112 (267) Show / Hide
Range on Protein: 72-171
Range on HMM: 5-112/267
Sequence Identity: 19% (21 aa)

QMHTSAMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAP--QDGKDDFYNASWVDgYSKKSAYIFAQAPF-------NDHTEYIFWRMVSERKPSMILV
.....| . .. . .. ......|  .. .. ..|| |    .  |||| .|. |   ...   | .|.|        .  ||| |. . |   .   .|
afekiaklakknatslskkvsedrrvevpllektrvvLkgygkrfkddfihAnvve-cpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqvvm

FGDIDEKQK
. |...   
lcdfveedg

Phosphatase M05D6.3.AA Subfamily.N20.PD 258-352 19 1.6e-06 18.8 In-house 157-250 (257) Show / Hide
Range on Protein: 258-352
Range on HMM: 157-250/257
Sequence Identity: 19% (18 aa)

EWADASKLPEYMLDMRASIKLQYIRSSKKTGVcIGPIMLVCATGVEKCAISATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACE
.  . .| |..     |   ..||| ..|. .  ||... |..|. .  .   .|...  | ..  .   . .. .. || |  .|   |  .. 
kqlqftkwpdhgtpasadsfikyiryarkshl-tgpmvvhcsagigrtgvflcvdvvfcaivkncsfnimdivaqmreqrsgmvqtkeqyhfcyd

Phosphatase M05D6.3.AA Subfamily.RN.PD 200-344 20 3.2e-06 17.5 In-house 107-249 (264) Show / Hide
Range on Protein: 200-344
Range on HMM: 107-249/264
Sequence Identity: 20% (29 aa)

ELKAKICRKFWPEKRSKkDFPTLSIQASDDH--SET-HMKTFNLTVTEKKQDHQTVLMHFYEWADASK--LPEYMLDMRASIKLQYIRSSkktgvCigPI
|   | |...||.. |.  .    ..   .|  ..   ...| |   ....      .||  | . .    .  .|..|  .   |   ||  ||.. | 
eegvkqckrywpdeGse-vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrs-----c--pi

MLVCATGVEKCAISATIDIIVSRITEE-HRVGFKETMSAIKMQRFGCFRTV
 |. .. .   ||....|..   ...    |.  .. || |  .|      
vvhcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktk

Sequence
Name Sequence Type Origin Length Description Download
M05D6.3.AA Protein None 397 None Fasta, JSON
M05D6.3.NA RNA None 1191 None Fasta, JSON
M05D6.3.AA.PD_69-359 Protein Phosphatase Domain None 291 None Fasta, JSON