• Phosphatome.Net

Gene T28F4.3

T28F4.3
Species: C.elegans
Alias: T28F4.3
External Links:
Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Superfamily: Cx5R-I
Family: Classic_PTP
Subfamily: N_Nematode_4
Protein domain

Protein domains of T28F4.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit phosphatase group/family/subfamily, which is helpful to understand the relationship between phosphatases. Transmembrane region is predicted by TMHMM 2.0. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking. View complete domain list.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Phosphatase T28F4.3.AA PTPc 55-315 27 2.8e-98 333.71 SMART 1-308 (308) Show / Hide 
Range on Protein: 55-315
Range on HMM: 1-308/308
Sequence Identity: 27% (86 aa)

KKAKISNMTREFRNNKEY-----KPNVTTSISEKMM--DKNRYR-HIFCGDDNRVVLKERD------PSNDYIHASWMVMP-DGFQFISTQGPIKNTIAD
. ... .. .........     ... |...... .  |||||. .| | |..||.|| ..      ...|||.|... ..  ....| |||| ..||.|
GFWEEFERLQRMTPWDLMSNYDPCCSCTCACWPENREMDKNRYKCDIPCYDHTRVKLKPPPGESHCYEGSDYINANYIDGYWRPKRYICTQGPLPHTIED

FWHMVYTEKCHVIVMLCQYIEE--------DQEKCQRYFSDTSEKEYGDYRVKVVEKTVELWNPVKVTGIQVQKKNC--------PTKHMVYHYFYYDWH
||.||. .|||.|||||. .|         ..|||..|. |. ...||...|. .....   . .... ..|....|        . ...|.|| | .| 
FWRMVWQQKCHIIVMLCNCMEKCTENRDQNGREKCHQYWPDE-PMTYGHITVTCKSEEKCP-DDYTMRTFEVTNTGCNCKYSMACSETRTVTHYHYTNWP

DQVAPLDPAPMIKMYKAVLNKSS---------------------SKPIVVHCSAGVGRTSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQ
|. .| .| ........| ...|                     . |||||||||.||| ||..|     .|..   ||. .|.|..|..| |.||.  |
DHGVPESPDSFLDFIRQVRHWQSHSPNMYMNMVSSNSKYHHTCPTGPIVVHCSAGCGRTGTFCAIDIMCQQIEN---VDIFQIVKMMRNQRPGMVQTEEQ

YVYLVVLMIELFI
|...   ..|.. 
YIFCYRCILEYIK
Phosphatase T28F4.3.AA Subfamily.N_Nematode_4.PD 58-315 57 4.1e-137 447.4 In-house 1-264 (264) Show / Hide 
Range on Protein: 58-315
Range on HMM: 1-264/264
Sequence Identity: 57% (153 aa)

KISNMTREFRNNKEyKPNVTTSISEKMMDKNRYRHIFCGDDNRVVLKERDPSNDYIHASWMVMPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQ
.||..||.|...|. .||||.|.|||..|||||..|.|.|..|||||.|||.|||||||||.|||.|..||||||.|.|..||||||||||..|.||||.
aiskltrdfvkgka-ppnvtasaseknsdknryadilcidetrvvlknrdpdndyihaswmrmPdkfryistqGPlketlsdfwhmvytekiavvvmlcd

YIEEDQEKCQRYFSDTSEK--EYGDYRVKVVEKTVE-----LWNPVKVTGIQvQKKNCPTKHMVYHYFYYDWH-DQVAPLDPAPMIKMYKAVLNKSSSKP
.|||..|||.||....|||  ..|.||...|||..|     ..|..|||... .||..|....|......||. |||||||.||.||.|||| .|...||
lieegvekcaryypeksekvvkfGkyritlvekkeeviadvilnslkvtnte-kkkdapseplvvkhvqvdwwrdqvaPldaapviklykavkkkkkekP

IVVHCSAGVGRTSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIELFI
||||||||||||.|.|||....|.|||||......|...||.|||.||||.||...|.|..|||||
ivvhcsaGvGrtatlvGidyatirirenseievldivrelramrlkavqshlqflfllvvlielfi
Phosphatase T28F4.3.AA Y_phosphatase 84-312 34 1e-89 309.13 Pfam 1-243 (243) Show / Hide 
Range on Protein: 84-312
Range on HMM: 1-243/243
Sequence Identity: 34% (85 aa)

MMDKNRYRHIFCGDDNRVVLKE--RDPSNDYIHASWMVMP--DGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQ-EK-CQRYFSD---TS
...||||. | | |..||.|.    |.. |||.|... .|   ....| |||| ..||.|||.||. .||..|||||. .|  . || |..|. |     
NKEKNRYKDIPCYDHTRVKLQPIPGDEDSDYINANYIDGPYWNPKAYICTQGPMPHTIEDFWRMVWQQKCTCIVMLCNCMEMGRDEKTCHQYWPDNKEGQ

EKEYGDYRVKVVEKTVELWNPVKVTGIQVQKKN--CPTKHMVYHYFYYDWHDQVAPLD-PAPMIKMYKAVLNKSS---SK--PIVVHCSAGVGRTSTFVG
...|||..|..|....   . . |.  .|.. .  .  ...|.|| | .| |. .| . | .|... . | ....   .   |||||||||.||| ||..
PMTYGDFQVTCVSEEH--CPDYTVRTFEVTN-GDQKQETRTVTHYHYTNWPDHGVPESQPKSMLDFIRQVRKWQPNPDHGCPPIVVHCSAGCGRTGTFCA

IYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIE
|     ..... .||. .|.|..|..| |.||.  ||...  ...|
IDIMCQQMEHEGTVDIFQIVKHMRNQRPGMVQTEEQYIFCYQCILE
Phosphatase T28F4.3.AA Subfamily.R_Nematode_3.PD 63-313 29 5.7e-56 181.4 In-house 3-265 (267) Show / Hide 
Range on Protein: 63-313
Range on HMM: 3-265/267
Sequence Identity: 29% (77 aa)

TREFRNNKEYKPNVTTSISeKMMDKNRYRHIFCGDDNRVVLKE--RDPSNDYIHASWMVMPDGFQFISTQGPI--------KNTIADFWHMVYTEKCHVI
..|.. .. .....||.| | ....|. .. .  ..|||||.     ..|.|||. . .|.| ..| ||.|         |.||  || |.  || ...|
ekafekiaklakknatsls-kkvsedrrvevpllektrvvLkgygkrfkddfihAnvvecpnglklIltqsPqkkdkekkkkstieKfwwmieqekveqv

VMLCQYIE---EDQEKCQRYFSDTSEK--EYGDYRVKVVEKTVELWNPVKVTGIQVqKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVlNKSSs
|||. .|   |..||| .|...  ..  . ... || .... || . |.   ..| . .   .. ||..| .| .. || .| ..... |.| .||  .|
vmlcdfveedgeeeekcseYypekvdgelkfegvsvkctdikkelsedvekrtlvv-tfekkkeftvthllykgWkelnapeepkealelikfv-eksk-

KPIVVHCSAGVGRTSTFVG-IYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIEL
.|||||.|..|. |..  ..  | .|......|.....| || .| ||.|..|.. .... ...|  
tpvvVHCsdGisRsatlaaielgyqliikskgkldllslikelrkqRagaiqtelelafvilgilkl
Phosphatase T28F4.3.AA Subfamily.R_Nematode_2.PD 58-311 33 6.6e-56 181.1 In-house 2-257 (261) Show / Hide 
Range on Protein: 58-311
Range on HMM: 2-257/261
Sequence Identity: 33% (86 aa)

KISNMTREFRNN-KEYKPNVTTSISEKMMDKNRYRHIFCGDDNRVVLKERDPSNDyIHASWMVMPD-GFQFISTQGPIKNTIADFWHMVYTEKCHVIVML
|. |.| |...  .  | .||.|.     ||.|| .. | .. .|. .  .   . ||| |.  .    .||.||||..||  ||| ||  ||.  ||||
kvvnltiesvvvatidkesvtesaaylpkdkhRypdvPCkpetavevivdgkrvp-ihanwvptagnpkrfiatqgPlentsedfWamviqekvekivml

CQYIEEDQEKCQRYFSDTSEK--EYGDYRVKVVEKTVELWNPVKVTGIQVQKKNC--PTKhMVYHYFYYDWHDQVAPLDPAPMIKMYKAVlnKSSSKPIV
|| .|. .|||..||. . ..  . | ...|.|..   | . .... ..|....   .|.  | || |.| |.  |   | . .. ..|  | | |||||
cqkvekekekceeYfpletsqkldlgrfsiktvsaekilkdeiekrtlkvedstgkfatr-tvthyqyeeWpdrgvPkshaelfeLlelv--kksekPiv

VHCSAGVGRTSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMI
|||||.||| .|.|.   .  . .. .. . | || ||  |  ..| . |..| . ..  
vhCsaGiGRtmafigteylareveadptieltealkelrehRwkgiqtesqlywltlgal
Phosphatase T28F4.3.AA Subfamily.N_Nematode_1.PD 63-314 33 2.6e-54 175.9 In-house 3-264 (265) Show / Hide 
Range on Protein: 63-314
Range on HMM: 3-264/265
Sequence Identity: 33% (88 aa)

TREFRNNKEYKPNVTTSISEKMMD--KNRYRHIFCGDDNRVVLKERDPSNDYIHASWMVMPD-GFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYI
|||. |..... ...  ..  .  ||||. . | |.|||.|.|   ..||||| .. .|    .|| .|.|...||||||.||. ||   |||||..||.
rdefralkkfndeekvkafkeaqeadknrykdvgcldknrvklaeeplpsdyihanyvgtptnpkrficaqaPldktiadfwymvlqekveaivmlckli

EEDQEKCQRYFSDTS--EKEYGDY--RVKVvEKTVEL------WNPVKVTGIQVQKKNCpTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVlnKSSSKP
 . ||. ||. ..  ..|. .   .. | |....        . .||| ..|.   . ... | ||. || |. .|     .... .||  ..| .||||
ekgkkkcaeyfpakegeklefkekgqkitv-enslgvkkleedeevikvtvlevegaGe-ktrkvthyqWtdWPdrGvPpadlaalelleav--rgskgP

IVVHCSAGVGRTSTFVGI-YLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIELF
|||||.||| | |.| |. . .. ...  || ...|..|  |  ..|..||...  .... |    
ivvhCsaGiGrtGtivaieyildkllegkqiedmeklvkkireqrnysiqtdaqylfvhrvllnyf
Phosphatase T28F4.3.AA Subfamily.R_Sponge_2.PD 75-310 31 1.1e-53 174.1 In-house 16-257 (262) Show / Hide 
Range on Protein: 75-310
Range on HMM: 16-257/262
Sequence Identity: 31% (76 aa)

NVTTSISEKMMDKNRYRHIFCGDDNRVVLKE-RDPSNDYIHASWM-VMPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQRYFSD
..... ... . |||.. |.  |..|| |..   .  ||| ||.. ..    ..|.||||.|.|..||| ||.  | . ||||..|...|||..|. .. 
slsiaklkenvgKnRfkeilpydmsRvrLrtdgskdsDYinAsfvdgykrrkayiatqgPlketveDfWRmvweykvstivmltnleengkekcakYWPe

T--SEKEYGDYRVKVVEKTVElwNPVKVTGIQVQKKNCPTKH-MVYHYFYYDWHDQVAPLDPAPMIKMYKAV---LNKSSSKPIVVHCSAGVGRTSTFVG
  |.|||...|...|..    .  ..  ....|..   ..  | .. .  | ..  | | ...... | |.|| .|.|.|.||.||||| ||. ..  . 
kvdeeveygkfkvtlkeeekl--adyiirklklskekssegeadvtqfhfvaWpehevPkdatsllelikrvlraqkksgnkaitvvCsdgvgrtGtfia

IYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLM
 .......|. |.|| |||.| | || . |||..   .      
ldsvlerlkaeeeidvfevlktlrtkriglvqdaaqYvfihdal
Phosphatase T28F4.3.AA Subfamily.R_Anemone_1.PD 76-312 34 1.1e-53 174.2 In-house 17-255 (258) Show / Hide 
Range on Protein: 76-312
Range on HMM: 17-255/258
Sequence Identity: 34% (82 aa)

VTTSISEKMMDKNRYRHIFCGDDNRVVLKE--RDPSNDYIHASWMVMPDG-FQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQRYFSD
. ..  ..  .|||| .|   |  ||||..   |.. ||| ||..   |.  .|| ||.|...|..|||.||  ||. ||||| .|| ...||..|. | 
kevarkaenkkknryadivaldhsRvvLeklsndeesdYinasylrasdktrafiatqapleetvedFWrmvwqekigviVmLtnliegekkkchqYwPd

tSEKEYGDYRVKVVEKtvELWNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVLNKS--SSKPIVVHCSAGVGRTSTFVGIYLS
|...||..||.. .|  |    . .. . ..||.  ....|..| .  | |.  |   . .... . |..|   ..|.||||||||||| .|. |.    
-stekygelrvslrkk--evfadyiirtlvlskkketeerevvqyhftvWpdkgvPqyatavLglrrkvqksslagarpvvvhCsaGvgRtGaflvidam

QIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIE
 ....  ||. ...|..|. |  .||.. |||..  ...|  
leqakkekvvDifnyvkairedrphmvqtkeqyvfihlavle
Phosphatase T28F4.3.AA Subfamily.N12.PD 58-313 27 7e-53 171.1 In-house 8-268 (270) Show / Hide 
Range on Protein: 58-313
Range on HMM: 8-268/270
Sequence Identity: 27% (73 aa)

KISNMTREFRNNKEYKPNVTTsiSEKMMDKNRYRHIFCGDDNRVVLKERDPSN--DYIHASWMVMPDG-FQFISTQGPIKNTIADFWHMVYTEKCHVIVM
|. .........|.|. ....  .|. . ||||. |.  | .||.|.. . ..  ||| |...  ..|  ..|..|||. .|. |||.|... ...||.|
klkklsekykaekvysteage--keenvkknrykDilPydksrvelskieeeegsdyinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvm

LCQYIEEDQEKCQRYFSDTSEKE--YGDYRVKVVEKTVeLWNPVKVTGIQVQKKncPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVL--NKSSSKPI
. .| .. ||.||.... |.|  .|...|.. |.   . .   .  ..|...   ....|| . | .| |.  |  . .......|   ..|...|.|||
aCrevelgkkkCeryWpeegeeelefgefevtleeeka-vdddflirtLkveaq--kesrkvyqfhytaWPDhgvPssaksllelielvrelqesedaPl

VVHCSAGVGRTSTFVGIYLSQIMIRE-NS--SVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIEL
|||||||| | . | . . .... .   ..|. ... .||. |  .||.. ||...   ..||   
vvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael
Phosphatase T28F4.3.AA Subfamily.N13.PD 64-311 31 9.1e-52 167.7 In-house 4-255 (259) Show / Hide 
Range on Protein: 64-311
Range on HMM: 4-255/259
Sequence Identity: 31% (79 aa)

REFRNNKEYKPNVTTSISEK--MMDKNRYRHIFCGDDNRVVLKERDPsndYIHASWM---VMPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQY
||.. .| ||  |.....|   .||||||...  |. || |..  .   || ||..   |  | ...| .|||. .|..|||.||.  |..||.|. .  
eefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg---yinaslikvpvgedeyeyiacqGPlPetvkdfwqmvweqkaeviamvtle

IEEDQEKCQRYFSDTSEKEYGDY-RVKVVEKTVELWNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVLN-KSSSKPIVVHCSA
|... ||.||. .. .|.   . |..|    |.  .  .|  ..|....    . | |  . .| |   |  .|..... . | ..... |||||||||.
kekgkvkchrywPerknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaelvqfvaevrllqtdagPivvhcsa

GVGRTSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMI
||. ... |.    .|  . ..|. ||...||  | | ||.. ||..    ..  
GiGrsGvlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykail
Phosphatase T28F4.3.AA Subfamily.N5_RR.PD 83-308 34 1.1e-51 167.4 In-house 22-258 (265) Show / Hide 
Range on Protein: 83-308
Range on HMM: 22-258/265
Sequence Identity: 34% (81 aa)

KMMDKNRYRHIFCGDDNRVVLKERDPSN---DYIHASWMVMPDGFQ--FISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQRYFSDTSEK-
.   ||||. |.  .  ||.|.......   .|| | ..  .|. .  ...||||. |||||||.|.|.|...||||| .  |....||..|| |. .  
gsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntiadfWrmiyqeevqvivmltklkeanrqkcavyfPdaedye

---EYGDYRVKVVEKtvELWNPVKVTGIQVQKKNCpTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVLNKSS---S--KPIVVHCSAGVGRTSTFVGIY
   .|||  .||.|.     |  .|. . ... .   .. |.||.| || |. .| |. ..... . | .. .       |.|||||||.|||  |..| 
iserygdveikveei--verndysvrklvlkyler-versvkhywytdWPdhksPddintlldlvleveesreeenaklaPvvvhcsaGiGrtGcfiais

LSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVV
..   .||.. ||...|  .||  | | ||.. || ..  
iavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihr
Phosphatase T28F4.3.AA Subfamily.RB.PD 73-313 31 2e-51 166.5 In-house 15-259 (261) Show / Hide 
Range on Protein: 73-313
Range on HMM: 15-259/261
Sequence Identity: 31% (78 aa)

KPNVTTSISEKMMDKNRYRHIFCGDDNRVVL--KERDPSNDYIHASWMVMPD-GFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQRY
. .|... ...  .|||...|   | .|| |   . ....||| |...       ..|.||||...|. |||.||. .|...|||| | .|. .|||..|
dqavkaaeeavnraknrftnilpydhsrvkLaalkdesdtdyinanyipgynspreyiatqGPlpetvddfWrmvwekkssiivmltqlvEkgkekceeY

FSDTS-EKEYGDYRVKVVEKTV-ELWnpvKVTGIQVQKKNCptKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVLNKS----SSKPIVVHCSAGVGRTST
. ... .  ||| .|......  . |    .  ....|..   |. | .| .  | |   | ........ ..| ..     |.|||||||||||||| |
WPadeepvlyGdikvtllaekeldew---virefkiekgke--krkvrqyhftsWpdhgvPektktlldfvrtvreaiekkaskkPivvHCsaGvGRtGt

FVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIEL
|. .      |.||  ||.. .. .||. |   ||.. ||...   ...|
fialdrllqaieendyvdvfgvvaelReeRnllvqtekqyifiheclldl
Phosphatase T28F4.3.AA Subfamily.N3.PD 71-307 30 1.2e-49 160.6 In-house 11-253 (261) Show / Hide 
Range on Protein: 71-307
Range on HMM: 11-253/261
Sequence Identity: 30% (73 aa)

EYKPNVTTSISEK--MMDKNRYRHIFCGDDNRVVLKERDPsnDYIHASWMVMPD-G----FQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQ
||....|.. |   ..||||| |   |. || ||| .   ||| |... |   .     ..|.||||...| .|||.||. .|...|||| ..|. . ||
rkkpglaisaarkpenlaknryrdilpydatrvklkeset--dyinanyvnmeipstglvnryiatqGplaktakdfWqmvweqkstlivmlttlverGr

EKCQRYFSDTSE-KEYGDYRVKVVEKtvELWNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVLNK--SSSKPIVVHCSAGVGR
 .|. .|..  |.|...|.. ..  .  . . .  . ...|.   ......  | .| |.  | |.| .... . | ..  ....|.|||||||.|||  
vkChqyWPetedelefgefsvrceke--detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigr

TSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLV
.. . ..  .| .. .| ...|....|  |   ||.. || ..    
tGvlilletalalieaaepvypldivrtmrdqramlvqtvsqykfvC
Phosphatase T28F4.3.AA Subfamily.RA.PD 72-310 31 1.7e-49 160.2 In-house 15-261 (266) Show / Hide 
Range on Protein: 72-310
Range on HMM: 15-261/266
Sequence Identity: 31% (78 aa)

YKPNVTTSISEKMMDKNRYRHIFCGDDNRVVLKER--DPSNDYIHASWMV-MPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQR
| .. |.  |. ..|||. .|.  | .||.|  .   .. ||| ||..    .  .||..||| ..|. ||| |..  |.. |||| .  | ..|||..|
qkeklrtankeenkkknrvvqilpydfsrvilsvkeGeeesdyinasfidGyrekdkfiaaqGpkeetvedfwrmiweqksativmltelkerkeekcaq

YFSDTSEKEYGDYRVKVVEKTVELWNPVKVTGIQVQKKNC--PTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVL--NKS-SSKPIVVHCSAGVGRTST
. |     ||. ||.| ..||     |.   .. . ...   .. .|  . .  | .   | ..  |.|. |.|   ..  ...||||||||||||| ||
ywpdeGlvtyGeirvevkdetvledytvrdflvtqlpdatrekksrlvrqfhftswpevGvpaegkGmlkllkkvkklqqqsanhpivvhcsaGvGrtGt

FVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLM
. .     ... .  .|. |..||||. |   ||.. ||...   . 
fivldavlervkaerkldvfeavkrlrlqrpqmvqtleqyefiykvl
Phosphatase T28F4.3.AA Subfamily.N_Choan_1.PD 74-308 30 1.9e-49 160.1 In-house 16-255 (262) Show / Hide 
Range on Protein: 74-308
Range on HMM: 16-255/262
Sequence Identity: 30% (71 aa)

PNVTTSISEKMMDKNRYRHIFCGDDNRVVL--KERDPSNDYIHASWMVM-PDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQRYF
| | ... . ||||. |.  |  || .  .|.. ..||| |...    .  ..| ||||. .....||.||. .| ..|||. .||... || ||. | .
ntataskadenvlknrysnivayDatrvkvtpneenkntDyinanfvpgykgekeyiatqgPvPaslvsfWqmvweqkvsaivmvtreieagklkChryW

SDTS-EKEYGDYRVKVVEKTVELWNpVKvTGIQVQKKNCPTKHmVYHYFYYDWHDQVAPLDPAPMIKMYKAVLNK---SSSKPIVVHCSAGVGRTSTFVG
 | ..||..|| .... .    ..   ........ |.. | .  |  | |. .| ... ...  ||||...  |.|.||||||||| |....  | . .
Pdenselklgdvtvkslseeekkty-ie-rkfkleresgetre-veqlaytaWPdhGvPattkellefrkavlkatkkktkaplvihCsaGvGrtGtyia

IY-LSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVV
 .... .|. .... ||  |   ||. .|| ..          
lDrlvkaveekaealdvkavvaelrkernlmvqtlvqyefvyk
Phosphatase T28F4.3.AA Subfamily.R_Anemone_2.PD 64-311 30 2e-49 160.1 In-house 4-258 (262) Show / Hide 
Range on Protein: 64-311
Range on HMM: 4-258/262
Sequence Identity: 30% (77 aa)

REFRN---NKEYKPNVTTSISEKMMDKNRYRHIFCGDDNRVVLKE--RDPSNDYIHASWMV-MPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQ
.|. .   ..|   ........    ||||  |   |. || |..   ... ||| |...       ..|.||.|. .|| |||||.  .. ||||| | 
eeyerlsrseetsvtlksalepvnkaknryanilaydktrvklqmlegeegsdyinanyidGyrrkkayiatqaPlpetiedfWrmvWeqnsavivmltq

YIEEDQEKCQRYFSDTSEKEYGDYRVKVVEKtVELwNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVLN---KSSSKPIVVHC
 |. . |..||. ..  ..||. .|.. |. ||| .   .  ..|...... . .|  . | .| |. .| ..| .... . | .   .|. .|||||||
eeergkakvhryWPskgsrsygklvvelkee-vel-sdyvlrsfkvkrteeeeerqvrqfhytsWpdegvpesgaslldlvrqvekaqqesgagpivvhc

SAGVGRTSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMI
|||||| .|. .      |.... ||. ...|.||. |   || . ||.....    
saGvGrtGvfiavdillerikaealvdvfqtvkqlreqrnlmvqtkdqyefiydvll
Phosphatase T28F4.3.AA Subfamily.RG.PD 73-313 28 4.8e-45 145.7 In-house 16-262 (264) Show / Hide 
Range on Protein: 73-313
Range on HMM: 16-262/264
Sequence Identity: 28% (70 aa)

KPNVTTSISEKMMDKNRYRHIFCGDDNRVVLKERDP--SNDYIHASWMV-MPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQRY
. ....| .|.   |||. .|.  .  || |..     ..||| ||..       ..| ||||.|.|| |||.|.. .. ..|||| .  |. ......|
dieaesskkeenkeknReinivaversRvklsplpgkdgkDYinAsyidGyrrskeyivtqgplketiedFWrmiWehnaqiivmltdldekgrrdedvy

FSD-TSEKEYGDYRVKVVEKTVELWNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYK--AVLNKSSSKPIVVHCSAGVGRTSTFVG
. .     |.....|....|..     |.   .. .|..  ....|..| | .| |. .|   .... . |  .  ||... |||||.||||||..|.. 
WPkkdeplelealkvtllskeklskytvrdfvlkntkddkekervvrqyhytkWPdmgsPestlfvlifvkkeeaankeeaGPivvhdsaGvgragtyia

IYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIEL
.   .  ......|.. ..||..|..| | |... |||..   ..||
ldtllqqlekeeavnvyqvlklirakRpglvtteEqyvfiydallel
Phosphatase T28F4.3.AA Subfamily.N6.PD 63-309 28 7.3e-45 145.1 In-house 15-289 (295) Show / Hide 
Range on Protein: 63-309
Range on HMM: 15-289/295
Sequence Identity: 28% (78 aa)

TREFRNNK--EYKPNVTTSIS--EKMMDKNRYRHIFCGDDNRVVLKER---DPSNDYIHASWMV----------MPDG----FQFISTQGPIKNTIADFW
..|| . .  | . . . . .   .  .||||. |.  |..||.||..    | .||| |...            ..      ..| |||..|.|..|||
weefeelqkqeseklysrkegekienkeknryknilPfDhtrvilkdgepsvpgsdYiNanyirlpkaskssgenveseehqkryiatqgcLkdtvsdFW

HMVYTEKCHVIVMLCQYIEEDQEKCQRYFSDTSE-KEYGDYRVKVVEKTVELWNPVKVTGIQVQKKNCpTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKA
.||. |...||||. . .|  ..|| ||. |... ||.|...|. .. . .    ..   .. ..|.  ... ...| .  | |.  |||  .... . |
rmvwqensrvivmttkevergknkCarYWPdeetkketGvitvtsisEkstadYtlRefsvshkdkdk-eareifqyhfkaWPdhgvpkdpgvvlnfled

VLNKS----SSKPIVVHCSAGVGRTSTFVGIYL-SQIMIRE--NSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVL
 .|.    .. |||||||||.||| ||. |    .|. ..  .  .|. ...|..|. |.| ||.. || ....  
vnkkqeelekagpivvhcsaGiGrtGtfividivlkiieqsgldvdidisksikdvrsqrsglvqteaqykfvyka
Phosphatase T28F4.3.AA Subfamily.N_Nematode_6.PD 62-312 29 9.8e-45 144.6 In-house 2-250 (253) Show / Hide 
Range on Protein: 62-312
Range on HMM: 2-250/253
Sequence Identity: 29% (73 aa)

MTREFRNNKEYKPNVTTSISEKMMDKNRYRHIFCGDDNRVVLKErDpSNDYIHASWMV-MPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIE
...|...  .  .. ...   |  |.|||. | | |  |..|.. |  . ||||. .  ...  ..| ||.|...|| .||.|..   . |||||. .|.
lkkeykdspneaseseataflkfkdrnrytniqCcdagrlklad-d-edfyihanlvkistkprrlictqaplegtieefwkmilssgveyivmlcelve

EDQEKCQRYFSDT--SEKEYGDYRVKVVEKTVElWNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVlnKSSSKPIVVHCSAGV
 .||. .|.||.   .. ....  .. .. ..  . . |  ...  |.   . .| |. . .| || .    ... ..|  |.. |||||||||||||| 
kgkeksaeylsdkvGdarkitklctvikigrkd-idkilvrslkrivkagdeevivkhihWanWPdhGvPdsflsalrllsvv--kkdkkPivvhCsaGv

GRTSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIE
|.. |      .|     .. ..| .||  |. ||| ..||.|    ..|    
GrtGtlaliliilealrlpdfqgvkdllvklreerfravqtevqylyalrcvle
Phosphatase T28F4.3.AA Subfamily.N9.PD 75-312 34 1.4e-44 144.2 In-house 17-272 (275) Show / Hide 
Range on Protein: 75-312
Range on HMM: 17-272/275
Sequence Identity: 34% (85 aa)

NVTTSISEKMMDKNRYRHIFCGDDNRVVLKER--DPSNDYIHASWMvmpDGFQ----FISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQR
....| .   ..||||  . | |. ||.|...  |.. |||.|...   ||..    ||.||||.|.|. ||| ||. ... ||||  . .|.. ||..|
tflasklranleknrytdvlcydetrvklakldedeasdyinanfv---dGykqkkafiatqGplkktvsdfwrmvweqevlvivmttrvvergrlkcgq

YFS--DTSEKEYGDYRVKVVEKTVElwNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVLNKSS---------------SKPIV
.   . | .|.||..|..||. ||  .  ||. ..... .   .  | |. .  | |   | . | .... ..| .| .|||||||||.||| ||. . .
ywpleeessaefgdlsvsnveveve--edykvrvleiknvkteesrkvthfqflswPdyGvPssaaslldvlekvrekqalavkelgdeskghlsgPPiv

VHCSAGVGRTSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIE
.   ..| . ||.|| .|.||| |  ..| . ||..  . ..|                  
vhcsaGiGrtGtfitldiclarleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
Phosphatase T28F4.3.AA Subfamily.R_Ecdysozoa.PD 75-310 32 1.7e-44 143.6 In-house 16-264 (269) Show / Hide 
Range on Protein: 75-310
Range on HMM: 16-264/269
Sequence Identity: 32% (80 aa)

NVTTSIS--EKMMDKNRYRHIFCGDDNRVVLKE--RDPSNDYIHASWMVMP-DGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEkCQRY
. .|..|  .    ||||..|   |..||.||.   . . ||| ||..    . ..||  |.|...|| ||| |.   . ..|||| .  | ... |..|
skstkvsekkenalknryedikafDktrvkLkkingkedsdyinasfikgykekkkfiaaqdPveatigDfWrmiaeqevtlivmlsnlteknrk-caky

FSDTSEKEYGDYRVKVVEKTVELWNPV-KVTGIQVQKKNCPTKHMVYHYFYYDWH-DQVAPLDPAPMIKMYKAV--LNKSS-----SKPIVVHCSAGVGR
...  |..|||  ||.|..         ...  .....  . .. |  | |  |. |. .|  .  ..|.. |  |.| .       ||||||||||||.
WpiedevqygdilvklvseekhsdyiireldvskkkeesvedsrkvvqysytgWksDskvPevargllklieqvrelyklnklsgsrsPivvhCsaGvgr

TSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLM
..|| . |    .... .||..|. | ||  |   |||  |||.|   . 
sgifvaldlllqqlkaedkvdifetvkkLrsqrnllvqsleqyvflyral
Phosphatase T28F4.3.AA Subfamily.N_Nematode_5.PD 62-312 27 2.5e-44 143.0 In-house 2-255 (258) Show / Hide 
Range on Protein: 62-312
Range on HMM: 2-255/258
Sequence Identity: 27% (71 aa)

MTREFRNNKEYKPNV-TTSISEKMMDKNRYRHIFCGDDNRVvlKERDPSNDYIHASWMVMPD-GFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYI
.  ||.. ...|||. |..  || ..|||. .. . |..||  |  |. ..||.||.. ..|   ..| || | ..|..||| ||| ||.. .|.|..  
lktefeklaslkpnketckafeknlkknrskdvkilDetrV--kltdeddsYinaskiklddlekkliltQlPlpdteedFWrmvyqekitsvvllvede

EEDQEKCqRYFSDTSE--KEYGDYRVKVVEKTVELWNPvKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIK-MYKAVLNKSSS--KPIVVHC
| .. ..  .| ....  ...|.  ... . .|.  .  |   ..|  ..|  .... .| .  |...| . ...|| . . ||.|...  .|.||....
elketav-sffpletgdylnlgkmfinnrkvevkedek-keytvevlpegcsesvfakvyhlttWkkkkvPdkvkkvikraiekvlskkqgknapvvvvs

SAGVGRTSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIE
|.||. ||... .    . ........|||| .|. |.|||.|  ||.... ....  
dlGlgRagtflllsvaieqlnngkepnideilkkirsqRpgavesliqyasvyaavld
Phosphatase T28F4.3.AA Subfamily.RK.PD 77-309 29 7.5e-44 141.5 In-house 22-261 (267) Show / Hide 
Range on Protein: 77-309
Range on HMM: 22-261/267
Sequence Identity: 29% (71 aa)

TTSISEKMMDKNRYRHIFCGDDNRVVLKERD-PSNDYIHASWMvmpDGF----QFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQY-IEEDQEKCQRYF
..  ..  .|||. .|   |  .|.|.  |  |.||| |...   |..    .|| ||||...|..||| .|| |.|  |||| .  .|. .|| .|. .
diakkdrnreknrsmdilaydrslvflisvdgdssdyinaali---dsykrpaafivtqgPlqetvkdfWrlvydencasivmlteldvevgrvkClkyW

SDTSEKEYGDYRVKVVEKTVELWNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQ-VAPLDPAPMIKMYKAVLNKSS---SKPIVVHCSAGVGRTSTFVG
 .|..||| .|..|| ...    |..  ..   ..   ...| .. .  | .    |     ..|. . | ....     .|||||.|| ||. ||. | 
PedtevrygdikvelveaeldadlvvrifrveklargqeeirevrqfqflgWpeyrdvPvskrsllklirrvkksqeeeeeGrivvhClaGaGrsGtfia

IYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVL
    ||.... ||. .. | ||. .   |. . ||...     
idivlemieregvvdvfnavktlrnrkvnmveteeqykfvydv
Phosphatase T28F4.3.AA Subfamily.N_Choan_2.PD 86-308 30 1.2e-43 140.8 In-house 23-259 (266) Show / Hide 
Range on Protein: 86-308
Range on HMM: 23-259/266
Sequence Identity: 30% (70 aa)

DKNRYRHIFCGDDNRVVLKE--RDPSNDYIHASWMVMP--DGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQRYFSDTSEKE--YG
|||. |      ||.|.|  .|.   || | ..     .  ..|...|| ..|. .|| |...|| . |||. .  |....||.||..  ....  . | 
rlnRyndiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkla

DYRVKVVEKTVELWNPVKVTGIQVQKKNcpTKHMVYHYFYYDWHDQVAPLDPA------PMIKMYKAVLNKSS----SKPIVVHCSAGVGRTSTFVGIYL
 .||.  . |  .   .| ....||.  ... . |..|..| |. .| ..        ..|| .|| . ....|..|||||||||| |.. |     .. 
dgkikvlalseekeegyiltrlrlekkg--etrrlvHfwyntWpdhgvpreedsslstdqllkmlravrrvrkeldkaePllvHcsaGvgRtGtliaiDi

SQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVV
|...||...|...||  |   || . || .|        
avrlLeetkkvdvlaiieelRkdRmalvqhpeqyellyk
Phosphatase T28F4.3.AA Subfamily.N1.PD 68-309 27 9.7e-41 131.6 In-house 12-264 (268) Show / Hide 
Range on Protein: 68-309
Range on HMM: 12-264/268
Sequence Identity: 27% (69 aa)

NNKEYKPNVTTSISEKMMDKNRYRHIFCGDDNRVVLKERDpsNDYIHASWMVMPD-GFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKC
. ||.. .....  ..  ..|||| .   |  |..|.. |  .||| || . ..  . ..| ||||. .|.  ||.||. .... ..|| . .|..| ||
eskekeletreaklpenrglnryrdvspydhsriklerad--vdyinaslveleeakrrYiLtqGPLphtadHFWqmvWeqnskavimLnkvvEknqikC

QRYFSDTSEK---EYGD--YRVKVVEKTVELWNPVKVtgIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVLNKS----SSKPIVVHCSAG
  |.   .|.   .. .  ..|| . . ..  . |.   .... ..    . ..|..|  | |   |  || ..|.   |...  |.|.|||||.||. |
aqywpqeeeeaellleetklkvkliseerksyflvrl--leLedletqetreilhfhyttwpdfgvpespaafLkfLfkvresgsLssdvgpavihCsag

VGRTSTFV--GIYLSQIMIREN-SSVDMVEILKRLRTMRLGAVQS--QLQYVYLVVL
..     | .|  ... ..||. . |  ||  |.| .|   ||.. |. .|      
igrsgtlslvdtclveiektgdlnavdikkvLlelRkyRvGLiqtpdqLrFsyiail
Phosphatase T28F4.3.AA Subfamily.N14.PD 71-312 30 1.3e-40 131.0 In-house 13-272 (275) Show / Hide 
Range on Protein: 71-312
Range on HMM: 13-272/275
Sequence Identity: 30% (76 aa)

EYKPNVTTSISEKMMDKNRYRHIFCGDDNRVVLK-ERDPSNDYIHASWM---VMPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKC
. . ...|.  ..  .|||....   .|||| |.  .. |..|| || .   |     ..| .|||...|. |||.||. .. ..|||| . .|. .||.
redallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfwqmvweqgvqlivmlteeeedgkeks

QRYFSDT----SEKEYGDYRvkVVEKTVELWNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMY---KAVLNKS---------SSKPI
 .|. ..    .. |.| ..  |..| .|  . |  ||....      .  |.|  | || |.  | |. ....     ..| .|.|. |..||||||||
fkylPkleskkktvefgkfk--vttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsfLeevqsvrrktnsevesvkeskPPv

VVHCSAGVGRTSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLVVLMIE
||   .   |    . .| ..|. ..|.|||. |   ||.  || ..  ..|.         
lvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLrkqrmllvqtlaqykfvykvlik
Phosphatase T28F4.3.AA Subfamily.RN.PD 64-307 30 4.4e-39 125.9 In-house 4-256 (264) Show / Hide 
Range on Protein: 64-307
Range on HMM: 4-256/264
Sequence Identity: 30% (78 aa)

REFRNNKEYKPNVTT---SISEKMMDKNRYRHIFCGDDNRVVLKERDP--SNDYIHASWMVMPDG--FQFISTQGPIKNTIADFWHMVYTEKCHVIVMLC
.|.   ..|. . .|   . .||...|||.....  |..|| |||.    ..||| || ..  |     .|.||||. .|||||| ||. . .|||.|..
kewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplsstiadfwqmvweqGvvvivnlt

QYIEEDQEKCQRYFSDTSEKEYGDYRVKVVEKTVelW-NPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVlNKS---SSKPIVV
  ||. ..|.||. |. .. |. | |..| . .  | .   |  . ..  .      |  . .  |... .|  . ..... . | |||    | |||||
rleeegvkqckrywpdeGsevyhiyevhlvsehi--wcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkv-nksyrGrscpivv

HCSAGVGRTSTFVGIYL-SQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLV
||.|.||| ... | |  . ...    .|..  |. ||  | | |... |. . . 
hcsdGaGrtGvyilidlvlerllkGvkeidiaatlehlrdqrpglvktkdqfefal
Phosphatase T28F4.3.AA Subfamily.N23.PD 96-309 30 1.1e-38 124.8 In-house 114-346 (350) Show / Hide 
Range on Protein: 96-309
Range on HMM: 114-346/350
Sequence Identity: 30% (71 aa)

GDDNRVVLK---ERDPSNDYIHASWM--VMPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQRYFSDTS--EKEYGDYRVKVVEK
| |||.|.   .    .||| |...  . |   .|| |||||..|.|||| ||. ..  ||||| .  | .. ||..|.       . .||.|| . ...
hdpnrvklqqstqpgqqddyinatylkeltpmsPpfiatqgPiastlaDFWlmvweqqssviVmltkevegnklkcdqYwPidegetnlfgdlrvslksl

TVElwNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVLNKS-----------SSKPIVVHCSAGVGRTSTFVGIYLSQIMIRE-
    .      ...|...  |.. | |  .  | .  .|  |  .... ..| .             . |||..||||||||| ||  .|   . ... |
rss--egwiervlhlqhndvstvrlvchlhtttWseiGvPksPedllaflgevetayaqqrktetegeggkPiilhCsaGvgRtgtfcvvysaireltag

NSSVDMVEILKRLRTMRLGAVQSQ--LQYVYLVVL
  ........|||  |   || .  |. .| .|| 
ngiiniprvvrrlrqqRkymvqkkvilkklyeavl
Phosphatase T28F4.3.AA Subfamily.RC.PD 105-311 26 6.5e-37 118.9 In-house 68-284 (288) Show / Hide 
Range on Protein: 105-311
Range on HMM: 68-284/288
Sequence Identity: 26% (57 aa)

ERDPSNDYIHASWMV-MPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQRYFsDTSEKEYGDYRVKVVEKTVELWNPVKVTGIQV
. . . .|| ||..    .  ..|..||| |.|. |||.|.. .| .||||| .  | |.||| .|. .  .. |||  |.. ..       ...  .. 
dseegskyinasfidsykkpekyiaaqGplketvddfwrmiferkvkvivmltelkeGdrekcaeyw-eeGkrayGdvevdlkdtdkssdyilrklelvn

QKKNcPTkHMVYHYFYYDWHDQVAPLDPAPMIKMYKAV------------LNKSSSKPIVVHCSAGVGRTSTFVGIYLSQIMIRENSSVDMVEILKRLRT
.|.   .   |... | .| ..  | .|  ..|. . |             ..  | |..|||..|..|| .|...      .  .||. ...|.||  |
kkrk-ds-revtqiqytswsveqlpeepkellkliqvvkqklpqkrsseafknfkstpllvhcrdGsqrtGifiallallesleaeekvdvfqvvkklrk

MRLGAVQSQLQYVYLVVLMI
 . |. . ||..|   ..  
arplmvsveeqyillydvlv
Phosphatase T28F4.3.AA Subfamily.N20.PD 84-312 32 6.5e-36 115.8 In-house 26-254 (257) Show / Hide 
Range on Protein: 84-312
Range on HMM: 26-254/257
Sequence Identity: 32% (73 aa)

MMDKNRYRHIFCGDDNRVVLKErdpSNDYIHASWMVM---PDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEDQEKCQRYFSDTSEKEYGD
.||||| |.  |  || | .   |.||| ||.. .    . . .|.||||. .|| |||.||  ... || |. . ||    || .|.  ..|     ..
nreknryrdilpydstrvplgk---skdyinasyirivncgeeyfyiatqgpllstiddfwqmvlennsnviamitreieggiikcyhywpislkkplel

YRVKVVEKTVELWNPVKVTGIQVQKKNCPTKHMVYHYFYYDWHDQVAPLDPAPMIKMYKAVLNKSSSKPIVVHCSAGVGRTSTFVGIYLSQIMIRENSSV
.|. .  .. . . .  .|| .|.  | | | .  .  | |. .|     .||  .   .   . |.|||||||.|||  |.. .    | .| |.....
khfrvflenyqilqyfiirmfqvvekstgtshsvkqlqftkwpdhgtpasadsfikyiryarkshltgpmvvhcsagigrtgvflcvdvvfcaivkncsf

DMVEILKRLRTMRLGAVQSQLQYVYLVVLMIE
|. ..|  | | ||.. || .   ...|    
nimdivaqmreqrsgmvqtkeqyhfcydivle
Phosphatase T28F4.3.AA PTPc_motif 213-312 32 6.1e-33 116.67 SMART 1-92 (92) Show / Hide 
Range on Protein: 213-312
Range on HMM: 1-92/92
Sequence Identity: 32% (34 aa)

MVYHYFYYDWHDQ-----VAPLDPAPMIKMYKAVLNKSSSKPIVVHCSAGVGRTSTFVGIYLSQIMIRENSSVDMVEILKRLRTMRLGAVQSQLQYVYLV
.|.|| |..| |.      .|    ..... ..| .     |||||||||.||| ||..|..   .      ||. ...|..|..| |.||.  ||... 
TVHHYHYTNWPDHVEKDSGVPE--DSILEFIRHVRK-----PIVVHCSAGCGRTGTFCAIDMMMQQ------VDIFQTVKEMRKQRPGMVQTEEQYIFCY

VLMIE
  ..|
RCILE
Phosphatase T28F4.3.AA Subfamily.N_Nematode_egg.PD 73-311 26 5.2e-28 89.8 In-house 15-253 (257) Show / Hide 
Range on Protein: 73-311
Range on HMM: 15-253/257
Sequence Identity: 26% (63 aa)

KPNVTTSISEKMMDKNRYRHIFCGDDNRVVLKERD--PSNDYIHASWMV-MPDGFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQYIEEdqEKCQRY
. ..||..|.  ..| | ... | .  || |. |    ..|.|||  .   |   .|| .| |.|||  ||| ||. ||..||||    |   |.|. |.
eislttaasdnylekarskrvhckessrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvedfwrmvfqekvqyivmltsakes--erceyy

FSDTSE--KE--YGDYRVKVVEKTVELWNPVKVTGIQVQKKNCPTKHmVYHyFYYDWHDQVAPLDPAPMIKMYkavlnKSSSKPIVVHCSAGVGRTSTFV
  . .       | .|.. ..   .     .|| ...   .   .. . | . .|..|  ....      .  |||.||..  || ...|.| | .. . 
wpkaeseslvtvpGslrienlkvdskadplfrvtklklvGgddeelf-leh-wqgdvnylsdvysplrvlrkl-----rnlskpvvvqdilGvskaatlv

GIYLSQI-MIRENSSV-DMVEILKRLRTMRLGAVQSQLQYVYLVVLMI
..|       . .  . ||  |  .|.| |.|...  |..        
aieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
Phosphatase T28F4.3.AA Subfamily.N_Fungi_PTP1.PD 72-189 30 4.7e-21 66.7 In-house 33-164 (343) Show / Hide 
Range on Protein: 72-189
Range on HMM: 33-164/343
Sequence Identity: 30% (40 aa)

YKPNVTTSISEKMMDKNRYRHIFCGDDNRVVLK----------ERDPSNDYIHASWMVMP-------DGFQFISTQGPIKNTIADFWHMVYTEKCHVIVM
.|  |   ... ||||. |.  . .|| ||              .|||| |... ..        .|..|.||.|...|.||.....  | .||..| . 
esddviissGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvils

LCQYIEEDQEKCQRYFSDTSekeYGDYRVKVVEKT
.| . |||.||. . |   | |. ||. .|     
ltsdvelnlekcyrYWqegs---ydditvklaskw
Phosphatase T28F4.3.AA Subfamily.N_Nematode_eak.PD 60-229 27 3.3e-17 54.3 In-house 3-171 (281) Show / Hide 
Range on Protein: 60-229
Range on HMM: 3-171/281
Sequence Identity: 27% (46 aa)

SNMTREFRNNKEYKPNVTTSISEKmMDKNRYRHIFCGDDNRVVLKERD-PSNDYIHASWMVMPD-GFQFISTQGPIKNTIADFWHMVYTEKCHVIVMLCQ
||.  .. .... .    |.  |. ...||  .|   | . | |       . || || . ... | ..| |  . .. .|| ||. .|   ||.| . .
snivadlddyqrllsirvtarlea-vnrnrvvkivpqdrylvrltssqlnrdGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlle

YIEEDQEKCQRYFSDTS-EKEYGDYRVKVVEKTVELwNPVKVTGIQVQKKNcpTKHMVYHYFYYDWHDQVAPL
||. || ..|| | . . .|| . |.  | .|.  | ...  ....| |    | |.|| ..| .   |    
dveekleksdkyfpdktevlkyGildverkeyavkr-niletrllilrkGn--ethrvlhykvfGwtettlpk
Phosphatase T28F4.3.AA Family.DSP.PD 197-303 23 1.1e-10 33.0 In-house 132-236 (387) Show / Hide 
Range on Protein: 197-303
Range on HMM: 132-236/387
Sequence Identity: 23% (27 aa)

KVTGI-QVQkK---NcPTK-HMVYhYFYYDWHDQ-VAPLDPApMIKMYKaVLNK--SSSKPIVVHCSAGVGRTSTFVGIYLSQImirENSSVDmvEILKR
.|| |  .. .   .  || . .. |  . . |  . ||.   ..| .. ....  .|.. ..||| ||.||. | . .|| .    |. . .  ||. .
gvtkivnlt-ddkpq-ftkelgik-ylripidDhnapplenl-fekaid-fieegndskgvVlVHCkaGkgRsgtliiaYlmks---egltle--ealdw

LRTMRLGAVQSQLQY
|  | | .. . .. 
vrskRpgvitpnqgf
Phosphatase T28F4.3.AA Subfamily.N_Fungi_PTP1.PD 205-303 26 1e-09 29.5 In-house 207-331 (343) Show / Hide 
Range on Protein: 205-303
Range on HMM: 207-331/343
Sequence Identity: 26% (32 aa)

KKNCPTkHMVYHYFYYDWHDQVAPLDPAPMIKMYK------------AVLNKSSSKPIVVHCSAGVGRTSTFVGIY--LSQIM----IRE--------NS
..  ..||.  .  |.|    |.|  .... .              |... |.||.|||||||||| |.| .   ||......        .   |... 
aavsep-yevyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaak

SVDMVE-ILKRLRTMRLGAVQSQLQY
|...||  |.  ||.  |.       
trDlisiivnelrkqrismvqnldqf
Phosphatase T28F4.3.AA Subfamily.PTEN.PD 153-306 20 1.2e-09 29.6 In-house 31-154 (305) Show / Hide 
Range on Protein: 153-306
Range on HMM: 31-154/305
Sequence Identity: 20% (32 aa)

VMLCQYIEEDQEKcQRYFSDTSEKEYGDYRVKVVEKTVElwnpvkvtgiqvqkkncptkhmvyhyfyydwhDQVAP-LD-PAPMIKMYKAVLNKSSSKPI
..| . . ... |  | ..  .|||. |.. .| .  ..                                |  .| |.   ....  .  |....|. .
lillltvykgkgk-lrilnargekedsdfdgrvavypfd--------------------------------DhnpptleLleeivedvdkwLkedksnVv

VVHCSAGVGRTSTFVGIYLSQIMIRENSSvDMVEILKRLRTMRLGAV--QSQLQYVYL
.||| || ||| . .  || . .|... . . ..| .. ||    .|   ||. ||. 
avHCkaGkGRtGvmicayLlksgikksad-ealaiydekRtkdkkGVtiPSQrRYvqY
Phosphatase T28F4.3.AA Subfamily.CDC14.PD 233-306 32 1.2e-08 26.5 In-house 185-251 (258) Show / Hide 
Range on Protein: 233-306
Range on HMM: 185-251/258
Sequence Identity: 32% (24 aa)

PMIKMYKAVLNKSsSKPIVVHCSAGVGRTSTFVGIYLsqiMIreNSSVDMVEILKRLRTMRLGAVQSQlQYVYL
..| .  ...|. .  |.||| ||.|||.|..| ||   ..  .  .   |..  || .| | | .. |  || 
ailkkfleiteka-eGaiavhCkaGLGrtgtligcyl---ik--hyrftaaetiawlriarPGsvigp-qqtyl
Phosphatase T28F4.3.AA Subfamily.PTPDC1.PD 213-302 24 1.3e-07 22.9 In-house 134-216 (229) Show / Hide 
Range on Protein: 213-302
Range on HMM: 134-216/229
Sequence Identity: 24% (22 aa)

MVYHYfYYDWHDQVAPlDPAPMIKMYKAVLNKSSSKPIVVHCSAGVGRTSTFVGIYLsqiMIRenSSVDMVEILKRLRTMRLGAVQSQLQ
.|.|  . ..|  ..     .. . | |    .   | ||| || |||   .  ||   .    . ..  | .| .|  |  ..|.. | 
giyfy-nfglkDygva-sleriLdivkvvdfaleegkiavHCHAGlGRtGvliacyl---vya--krltaeeaiklvrskrpksiqtreq
Phosphatase T28F4.3.AA Subfamily.PRL.PD 235-303 24 1e-06 20.2 In-house 69-132 (140) Show / Hide 
Range on Protein: 235-303
Range on HMM: 69-132/140
Sequence Identity: 24% (17 aa)

IKMYKAVLNKSSSKPIVVHCSAGVGRTSTFVGIYLSQIMIRENSSVDMVeilkrlRTMRLGAVQ-SQLQY
... |.  ...... . ||| ||.||.  .| . | .  .. . .|...      |. | ||.   ||..
lellkekfkeepkstvavhcvaGlGraPvlvalalieaGmkyedavefi------rekrrgainskqlkf
Phosphatase T28F4.3.AA Subfamily.DSP23.PD 244-299 25 1.3e-06 20.2 In-house 63-113 (128) Show / Hide 
Range on Protein: 244-299
Range on HMM: 63-113/128
Sequence Identity: 25% (14 aa)

KSSSKPIVVHCSAGVGRTSTFVGIYLsqIMIRENSSVDMVeilKRLRTMRLGAVQS
. . ... |||  |.||| |..  ||  .  .. .. | .     .|  | |....
ekkeeavgvhcalGlGrtGtllacyl--vkeeglaaddai---aevrkrrkGsiet
Phosphatase T28F4.3.AA Subfamily.PTPMT1.PD 245-291 34 2e-06 19.3 In-house 84-128 (146) Show / Hide 
Range on Protein: 245-291
Range on HMM: 84-128/146
Sequence Identity: 34% (16 aa)

SSSKPIVVHCSAGVGRTSTFVGIYLsqIMIRENSSVDMVEILKRLRT
|  . . ||| || .| .| |. ||  .. .. |. . |..||. | 
skgssvYvHCkAGrtRsatlvacyl--mkkkklspeeavkflkkkRp
Phosphatase T28F4.3.AA Family.OCA.PD 207-267 18 7.8e-06 17.3 In-house 52-112 (165) Show / Hide 
Range on Protein: 207-267
Range on HMM: 52-112/165
Sequence Identity: 18% (11 aa)

NCPTKHMVYHYFYYD-WHDQVAPLDPAPMIKMYKAVLNKSsSKPIVVHCSAGVGRTSTFVGI
. .... ....  |  .... ..  . .... | .|..    |...||  |. ||.. ||. 
fveeeniklihikvdkkkkdlveieeellkrvlkilldvd-nypvlihcnkGkhrtglvvgc
Phosphatase T28F4.3.AA Subfamily.OCA.PD 207-267 18 7.8e-06 17.3 In-house 52-112 (165) Show / Hide 
Range on Protein: 207-267
Range on HMM: 52-112/165
Sequence Identity: 18% (11 aa)

NCPTKHMVYHYFYYD-WHDQVAPLDPAPMIKMYKAVLNKSsSKPIVVHCSAGVGRTSTFVGI
. .... ....  |  .... ..  . .... | .|..    |...||  |. ||.. ||. 
fveeeniklihikvdkkkkdlveieeellkrvlkilldvd-nypvlihcnkGkhrtglvvgc
Sequence
Name Sequence Type Origin Length Description Download
T28F4.3.AA Protein None 490 None Fasta, JSON
T28F4.3.NA RNA None 1470 None Fasta, JSON
T28F4.3.AA.PD_55-315 Protein Phosphatase Domain None 261 None Fasta, JSON